Cited by 34Gastrointestinal motility and disordersGut microbiota and healthInfant Health and Development

Dietary Renaissance in IBS: Has Food Replaced Medications as a Primary Treatment Strategy?

Spencer, Marisa, Chey, William D., Eswaran, Shanti·2014·Current Treatment Options in Gastroenterology

Abstract

Opinion statement The medical community has only recently started to focus attention on the role of food in the pathogenesis of irritable bowel syndrome (IBS), though the association between food and gastrointestinal (GI) symptoms has been recognized by patients for decades. Health care providers receive little formal training in the dietary management of IBS and have traditionally viewed dietary interventions with skepticism. There is mounting evidence that links food to changes in motility, visceral sensation, microbiome, permeability, immune activation, and brain-gut interactions-all key elements in the pathogenesis of IBS. The role of specific dietary modification in the management of IBS has not been rigorously investigated until recently. There is now credible evidence suggesting that targeted dietary carbohydrate exclusion provides clinical benefits to IBS patients. There is emerging evidence to suggest that proteins such as gluten, as well as food chemicals, may play a role in IBS.

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Crossref · 10.1007/s11938-014-0031-x

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  • There are multiple mechanisms by which food may trigger symptoms in IBS, including primary effects (eg, osmotic, chemical, immunological, mechanical or neuroendocrine) and secondary effects (eg, fermentation by-products, alterations in intraluminal pH or effects on the gut microbiome).

    “There are multiple mechanisms by which food may trigger symptoms in IBS, including primary effects (eg, osmotic, chemical, immunological, mechanical or neuroendocrine) and secondary effects (eg, fermentation by-products, alterations in intraluminal pH or effects on the gut microbiome).193 194”

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Authors
Spencer, M., Chey, W. D., & Eswaran, S.
Affiliations
A. Alfred Taubman Health Care Center (US)
Corresponding author
Eswaran, Shanti
Venue
Current Treatment Options in Gastroenterology
Published
2014-09-16
Volume
12
Issue
4
Pages
424-440
ISSN
  • 1092-8472 (ISSN-L)
  • 1534-309X
OpenAlex
W2074609492
Cited by
34
References
100
Citations by year
2026: 1 · 2025: 1 · 2023: 2 · 2022: 2 · 2021: 7 · 2020: 2 · 2019: 6 · 2018: 4 · 2017: 3 · 2016: 3 · 2015: 3
FWCI
2.99
Type
journal article
Language
en
Open access
closed
Locations
  • Current Treatment Options in Gastroenterology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Health Professions › Pharmacy › Infant Health and Development
Keywords
irritable bowel syndrome, dietary management, gluten, food intolerance, gut microbiota, gut-brain axis, visceral sensation, gastrointestinal motility

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