Cited by 25Mindfulness and Compassion InterventionsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychotherapy Techniques and Applications

Psychological outcomes and mechanisms of mindfulness-based training for generalised anxiety disorder: A systematic review and meta-analysis

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Williams, Monique, Honan, Cynthia, Skromanis, Sarah, Sanderson, Ben, Matthews, Allison J.·2024·Current Psychology

Abstract

Abstract This systematic review aimed to identify 1) the effect of mindfulness training on pre-post measures of anxiety and attention among adults experiencing high levels of generalised anxiety; and 2) the impact of predictors, mediators and moderators on post-intervention changes in anxiety or attention. Trait mindfulness and distress measures were included as secondary outcomes. A systematic search was conducted in November 2021 in electronic databases using relevant search terms. Eight articles comprising four independent studies were included ( N = 334). All studies included participants diagnosed with generalised anxiety disorder (GAD) who participated in an 8-week manualised program. The meta-analysis indicated that mindfulness training had a large effect on anxiety symptoms ( g = -1.92, 95% CI [-3.44, -0.40]) when compared to inactive (i.e., care as usual, waitlist) or non-specified (i.e., condition not defined) controls. However, a significant effect was not found when compared to active controls. Effects for depression, worry and trait mindfulness did not reach statistical significance, despite small-large effect sizes favouring mindfulness compared to inactive/non-specified controls. Our narrative review found evidence that changes in aspects of trait mindfulness mediate anxiety reduction following mindfulness training. However, a small number of studies were available for inclusion in the review, with high risk of bias and low certainty of evidence present. Overall, the findings support the use of mindfulness training programs for GAD and indicate mechanisms that may differ from those involved in other cognitive therapy approaches. Further RCTs with evidence-based controls are needed to clarify techniques most beneficial for generalised anxiety to support individually tailored treatment.

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  • Meta-analyses and systematic reviews have presented contradictory results regarding the improvement of anxiety symptoms with MBI compared with inactive control groups.

    “Metaanalyses and systematic reviews (Che-Sheng et al., 2018; Williams et al., 2023) have presented contradictory results regarding the improvement of anxiety symptoms with MBI compared with inactive control groups.”

    From Analysis of the Efficacy of Mindfulness Meditation in a Mutual Aid Group for Bipolar Disorder (2024) · cites this paper as Williams et al., 2023

    The Results of Syntheses report significantly greater reductions in anxiety symptoms with mindfulness programs than with inactive/non-specified controls. The Discussion notes substantial heterogeneity, but does not say that reviews reached contradictory conclusions for this comparison. This source supports one result in the cited contrast, not the characterization of the results as contradictory. (LLM, conf=0.79)

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  • The pharmacological management of anxiety disorders in BD involves drugs that lead to adverse events.

    “The pharmacological management of anxiety disorders in BD involves drugs that lead to adverse events (Williams et al., 2023).”

    From Analysis of the Efficacy of Mindfulness Meditation in a Mutual Aid Group for Bipolar Disorder (2024) · cites this paper as Williams et al., 2023

    The Introduction and Discussion passages address generalized anxiety disorder and mindfulness-based treatment, not pharmacological management of anxiety in BD. Searches for BD, pharmacological treatment, and adverse drug effects found no passage in our copy that addresses the attributed claim. (LLM, conf=0.75)

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2 of the 75 references couldn’t be matched to a known paper.

Research works printed but not linked: 4

  1. Clarivate (2022, June 23). Journal citation reports. https://jcr-clarivate-com.ezproxy.utas.edu.au/jcr/home?app=jcr&Init=Yes&authCode=null&SrcApp=IC2LS
  2. Higgins, J. P. T., Thomas, J., Chandler, J., Cumpston, M., Li, T., Page, M. J., & Welch, V. A. (Eds.). (2022). Cochrane handbook for systematic reviews of interventions version 6.3 (updated February 2022). Cochrane, 2022. https://www.training.cochrane.org/handbook
  3. NICE (National Institute for Health and Care Excellence) (2020). Generalised anxiety disorder and panic disorder in adults: Management. https://www.nice.org.uk/guidance/cg113 31961629
  4. Veritas Health Innovation Covidence systematic review software 2022 Retrieved from www.covidence.org

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Authors
Williams, M., Honan, C., Skromanis, S., Sanderson, B., & Matthews, A. J.
Affiliations
University of Tasmania (AU)
Corresponding author
Williams, Monique
Venue
Current Psychology
Published
2023-05-11
Volume
43
Issue
6
Pages
5318-5340
ISSN
  • 1046-1310 (ISSN-L)
  • 1936-4733
OpenAlex
W4382182044
Cited by
25
References
75
Citations by year
2026: 7 · 2025: 8 · 2024: 8 · 2023: 2
FWCI
1.27
Type
journal article
Language
en
Open access
Locations
  • Current Psychology (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
University of Tasmania
Topics
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Keywords
mindfulness training, generalized anxiety disorder, anxiety symptoms, trait mindfulness, attention, mediation, moderators, predictive factors, worry, depression

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