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Cited by 66Substance Abuse Treatment and OutcomesMindfulness and Compassion InterventionsOpioid Use Disorder Treatment

Mindfulness-Based Relapse Prevention for Stimulant Dependent Adults: A Pilot Randomized Clinical Trial

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Glasner, Suzette, Mooney, Larissa J., Ang, Alfonso, Garneau, Hélène Chokron, Hartwell, Emily, Brecht, Mary-Lynn, Rawson, Richard A.·2017·Mindfulness
DOI 10.1007/s12671-016-0586-9PMC PMC5300086
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Abstract

In light of the known associations between stress, negative affect, and relapse, mindfulness strategies hold promise as a means of reducing relapse susceptibility. In a pilot randomized clinical trial, we evaluated the effects of Mindfulness Based Relapse Prevention (MBRP), relative to a health education control condition (HE) among stimulant dependent adults receiving contingency management. All participants received a 12-week contingency management (CM) intervention. Following a 4-week CM-only lead in phase, participants were randomly assigned to concurrently receive MBRP (n=31) or HE (n=32). Stimulant dependent adults age 18 and over. A university based clinical research center. The primary outcomes were stimulant use, measured by urine drug screens weekly during the intervention and at 1-month post-treatment, negative affect, measured by the Beck Depression Inventory and Beck Anxiety Inventory, and psychiatric severity, measured by the Addiction Severity Index. Medium effect sizes favoring MBRP were observed for negative affect and overall psychiatric severity outcomes. Depression severity changed differentially over time as a function of group, with MBRP participants reporting greater reductions through follow-up (p=0.03; Effect Size=0.58). Likewise, the MBRP group evidenced greater declines in psychiatric severity, (p=0.01; Effect Size=0.61 at follow-up). Among those with depressive and anxiety disorders, MBRP was associated with lower odds of stimulant use relative to the control condition (Odds Ratio= 0.78, p=0.03 and OR=0.68, p=0.04). MBRP effectively reduces negative affect and psychiatric impairment, and is particularly effective in reducing stimulant use among stimulant dependent adults with mood and anxiety disorders.

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  • A recent randomized trial comparing MBRP to contingency management showed greater reductions in stimulant use in the MBRP arm, particularly among those with depression and anxiety disorders.

    “A recent randomized trial compared MBRP to contingency management and showed greater reductions in stimulant use in the MBRP arm, particularly among those with depression and anxiety disorders (Glasner et al., 2017).”

    From Mindfulness-Based Relapse Prevention in a Jail Drug Treatment Program. (2019) · cites this paper as Glasner et al., 2017

    The Abstract and Introduction say the trial compared MBRP with health education while all participants received contingency management; it did not compare MBRP against contingency management. The Results report no significant overall difference in stimulant use between groups, but significantly lower odds of use with MBRP among participants with major depressive disorder or generalized anxiety disorder. (LLM, conf=0.91)

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  • For people living with major depressive and general anxiety disorders, eight 60-minute weekly mindfulness relapse prevention group sessions reduced ratings of depression and anxiety symptoms over a health education group in the setting of a 12-week contingency management program.

    “For people living with major depressive and general anxiety disorders, eight 60-minute weekly mindfulness relapse prevention group sessions reduced ratings of depression and anxiety symptoms over a health education group in the setting of a 12-week contingency management program (62).”

    From Clinical management of psychostimulant withdrawal: review of the evidence (2023) · cites this paper as [62]

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Authors
Glasner, S., Mooney, L. J., Ang, A., Garneau, H. C., Hartwell, E., Brecht, M.-L., & Rawson, R. A.
Affiliations
University of California, Los Angeles (US)
Corresponding author
Glasner, Suzette
ORCID
Venue
Mindfulness
Publisher
Springer Science and Business Media LLC
Published
2016-08-04
Volume
8
Issue
1
Pages
126-135
ISSN
  • 1868-8527 (ISSN-L)
  • 1868-8535
DOI
10.1007/s12671-016-0586-9
PMC
PMC5300086
OpenAlex
W2478117043
Cited by
66
References
49
Citations by year
2026: 1 · 2025: 2 · 2024: 7 · 2023: 8 · 2022: 6 · 2021: 12 · 2020: 8 · 2019: 4 · 2018: 9 · 2017: 7 · 2016: 1 · 2015: 1
FWCI
6.57
Type
journal article
Language
en
Open access
Licence
Locations
  • Mindfulness (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Funders
National Institute on Drug Abuse (K23 DA020085, T32 DA07272-21)
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Keywords
mindfulness-based relapse prevention, stimulant use disorder, contingency management, relapse prevention, negative affect, depression, anxiety, psychiatric symptom severity, stimulant use, substance use disorders, mood disorders, anxiety disorders

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