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Cited by 345Neural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on BehaviorSubstance Abuse Treatment and Outcomes

Inhibitory control and emotional stress regulation: Neuroimaging evidence for frontal–limbic dysfunction in psycho-stimulant addiction

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Li, Chiang-shan Ray, Sinha, Rajita·2008·Neuroscience & Biobehavioral Reviews
DOI 10.1016/j.neubiorev.2007.10.003PMC PMC2263143
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Abstract

This review focuses on neuroimaging studies that examined stress processing and regulation and cognitive inhibitory control in patients with psycho-stimulant addiction. We provide an overview of these studies, summarizing converging evidence and discrepancies as they occur in the literature. We also adopt an analytic perspective and dissect these psychological processes into their sub-components, to identify the neural pathways specific to each component process and those that are more specifically involved in psycho-stimulant addiction. To this aim we refer frequently to studies conducted in healthy individuals. Despite the separate treatment of stress/affect regulation, stress-related craving or compulsive drug seeking, and inhibitory control, neural underpinnings of these processes overlap significantly. In particular, the ventromedial prefrontal regions including the anterior cingulate cortex, amygdala and the striatum are implicated in psychostimulant dependence. Our overarching thesis is that prefrontal activity ensures intact emotional stress regulation and inhibitory control. Altered prefrontal activity along with heightened striatal responses to addicted drug and drug-related salient stimuli perpetuates habitual drug seeking. Further studies that examine the functional relationships of these neural systems will likely provide the key to understanding the mechanisms underlying compulsive drug use behaviors in psycho-stimulant dependence.

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  1. Acton G. Measurement of impulsivity in a hierachical model of personality: implications for substance use. Substance Use Misuse. 2003;38:67–83. doi: 10.1081/ja-120016566. [DOI] [PubMed] [Google Scholar] · DOI
  2. Alexander GE, DeLong MR, Strick PL. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu. Rev. Neurosci. 1986;9:357–381. doi: 10.1146/annurev.ne.09.030186.002041. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  3. Amieva H, Lafont S, Rouch-Leroyer I, Rainville C, Dartigues JF, Orgogozo JM, Fabrigoule C. Evidencing inhibitory deficits in Alzheimer's disease through interference effects and shifting disabilities in the Stroop test. Arch Clin Neuropsychol. 2004;19:791–803. doi: 10.1016/j.acn.2003.09.006. [DOI] [PubMed] [Google Scholar] · DOI
  4. Armstrong IT, Munoz DP. Inhibitory control of eye movements during oculomotor countermanding in adults with attention-deficit hyperactivity disorder. Exp Brain Res. 2003:444–452. doi: 10.1007/s00221-003-1569-3. [DOI] [PubMed] [Google Scholar] · DOI
  5. Arnsten AF, Goldman-Rakic PS. Noise stress impairs prefrontal cortical cognitive function in monkeys: evidence for a hyperdopaminergic mechanism. Arch Gen Psychiatry. 1998;55:362–368. doi: 10.1001/archpsyc.55.4.362. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  6. Aron AR, Fletcher PC, Bullmore ET, Sahakian BJ, Robbins TW. Stop-signal inhibition disrupted by damage to right inferior frontal gyrus in humans. Nature Neuroscience. 2003;6:115–116. doi: 10.1038/nn1003. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  7. Aron AR, Poldrack RA. The cognitive neuroscience of response inhibition: relevance for genetic research in attention-deficit/hyperactivity disorder. Biol Psychiatry. 2005;57:1285–1292. doi: 10.1016/j.biopsych.2004.10.026. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  8. Askenazy F, Sorci K, Benoit M, Lestideau K, Myquel M, Lecrubier Y. Anxiety and impulsivity levels identify relevant subtyps in adolescents with at-risk behavior. Journal of Affective Disorders. 2003;74:219–227. doi: 10.1016/s0165-0327(02)00455-x. [DOI] [PubMed] [Google Scholar] · DOI
  9. Back S, Dansky BS, Coffer SF, Saladin ME, Sonne S, Brady KT. Cocaine dependence with and without posttraumatic stress disorder: A comparison of substance use, trauma history and psychiatric comorbidity. The American Journal on Addictions. 2000;9:51–62. doi: 10.1080/10550490050172227. [DOI] [PubMed] [Google Scholar] · DOI
  10. Badcock JC, Michie PT, Johnson L, Combrinck J. Acts of control in schizophrenia: dissociating the components of inhibition. Psychol Med. 2002:32. doi: 10.1017/s0033291701005128. [DOI] [PubMed] [Google Scholar] · DOI
  11. Ball T, Schreiber A, Feige B, Wagner M, Lucking CH, Kristeva-Feige R. The role of higher-order motor areas in voluntary movement as revealed by high-resolution EEG and fMRI. Neuroimage. 1999;10:682–694. doi: 10.1006/nimg.1999.0507. [DOI] [PubMed] [Google Scholar] · DOI
  12. Bar-On R, Tranel D, Denburg N, Bechara A. Exploring the neurological substrate of emotional and social intelligence. Brain. 2003;126:1790–1800. doi: 10.1093/brain/awg177. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  13. Bark R, Dieckman S, Bogerts B, Northoff G. Deficit in decision making in catatonic schizophrenia: An exploratory study. Psychiatry Research. 2005;134:131–141. doi: 10.1016/j.psychres.2004.04.013. [DOI] [PubMed] [Google Scholar] · DOI
  14. Beale IL, Matthew PJ, Oliver S, Corballis MC. Performance of disabled and normal readers on the Continuous Performance Test. J Abnorm Child Psychol. 1987;15:229–238. doi: 10.1007/BF00916351. [DOI] [PubMed] [Google Scholar] · DOI
  15. Becerra L, Breiter HC, Wise R, Gonzalez RG, Borsook D. Reward circuitry activation by noxious thermal stimuli. Neuron. 2001;32:927–946. doi: 10.1016/s0896-6273(01)00533-5. [DOI] [PubMed] [Google Scholar] · DOI
  16. Bechara A, Damasio H. Decision-making and addiction (Part I): Impaired activation of somatic states in substance dependent individuals when pondering decisions with negative future consequences. Neuropsychologia. 2002;40:1675–1689. doi: 10.1016/s0028-3932(02)00015-5. [DOI] [PubMed] [Google Scholar] · DOI
  17. Bechara A, Damasio H, Damasio AR. Emotion, decision making, and the orbitofrontal cortex. Cerebral Cortex. 2000;10:295–307. doi: 10.1093/cercor/10.3.295. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  18. Bechara A, Damasio H, Tranel D, Damasio AR. The Iowa Gambling Task and the somatic marker hypothesis: Some questions and answers. Trends in Cognitive Sciences. 2005;9:159–162. doi: 10.1016/j.tics.2005.02.002. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  19. Bechara A, Martin EM. Impaired decision making related to working memory deficits in individuals with substance addictions. Neuropsychology. 2004;18:152–162. doi: 10.1037/0894-4105.18.1.152. [DOI] [PubMed] [Google Scholar] · DOI
  20. Bechara A, Tranel D, Damasio H, Damasio AR. Failure to respond autonomically to anticipated future consequences following damage to prefrontal cortex. Cereb Cortex. 1996;6:215–225. doi: 10.1093/cercor/6.2.215. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  21. Berendse HW, et al. Topographical organization and relationship with ventral striatal compartments of prefrontal corticostriatal projections in the rat. J. Comp. Neurol. 1992;316:314–347. doi: 10.1002/cne.903160305. [DOI] [PubMed] [Google Scholar] · DOI
  22. Bertelson P, Tisseyre F. The time-course of preparation with regular and irregular foreperiods. Quat J Exp Psychol. 1968;20:297–300. doi: 10.1080/14640746808400165. [DOI] [PubMed] [Google Scholar] · DOI
  23. Bertolino A, Arciero G, Rubino V, Latorre V, De Candia M, Mazzola V, Blasi G, Caforio G, Hariri AR, Kolachana B, Nardini M, Weinberger D, Scarabino T. Variation of human amygdala response during threatening stimuli as a finction of 5′HTTLPR genotype and personality style. Biological Psychiatry. 2005;57:1517–1525. doi: 10.1016/j.biopsych.2005.02.031. [DOI] [PubMed] [Google Scholar] · DOI
  24. Bickel WK, Marsch LA. Toward a behavioral economic understanding of drug dependence: delay discounting processes. Addiction. 2001;96:73–86. doi: 10.1046/j.1360-0443.2001.961736.x. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  25. Bickel WK, Miller ML, Yi R, Kowal BP, Lindquist DM, Pitcock JA. Behavioral and neuroeconomics of drug addiction: Competing neural systems and temporal discounting processes. Drug Alcohol Depend. doi: 10.1016/j.drugalcdep.2006.09.016. In Press. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI · Paper page
  26. Bindra D. How adaptive behavior is produced: a perceptual motivational alternative to response reinforcement. Behavioral and Brain Sciences. 1978;1:41–91. [Google Scholar]
  27. Bolla KI, Eldreth DA, London ED, Kiehl KA, Mouratidis M, Contoreggi C, Matochik JA, Kurian V, Cadet JL, Kimes AS, Funderburk FR, Ernst M. Orbitofrontal cortex dysfunction in abstinent cocaine abusers performing a decision-making task. Neuroimage. 2003;19:1085–1094. doi: 10.1016/s1053-8119(03)00113-7. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  28. Bolla K, Ernst M, Kiehl K, Mouratidis M, Eldreth D, Contoreggi C, Matochik J, Kurian V, Cadet J, Kimes A, Funderburk F, London E. Prefrontal cortical dysfunction in abstinent cocaine abusers. Journal of Neuropsychiatry Clin Neuroscience. 2004;16:456–464. doi: 10.1176/appi.neuropsych.16.4.456. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  29. Brady KT, Killeen T, Saladin ME, Dansky BS, Necker S. Comorbid substance abuse and post-traumatic stress disorder: Characteristics of women in teatment. American Journals on Addictions. 1994;3:160–164. [Google Scholar]
  30. Brady KT, Sinha R. Co-occurring mental and substance use disorders: the neurobiological effects of chronic stress. Am J Psychiatry. 2005;162:1483–1493. doi: 10.1176/appi.ajp.162.8.1483. [DOI] [PubMed] [Google Scholar] · DOI
  31. Brand M, Fujiwara E, Borsutsky S, Kalbe E, Kessler J, Markowitsch H. Decision-making deficits of Korsakoff patients in a new gambling task with explicit rules: Associations with executive functions. Neuropsychology. 2005;19:267–277. doi: 10.1037/0894-4105.19.3.267. [DOI] [PubMed] [Google Scholar] · DOI
  32. Breese GR, Chu K, Dayas CV, Funk D, Knapp DJ, Koob GF, Lê AD, O'Dell LE, Overstreet DH, Roberts AJ, Sinha R, Valdez GR, Weiss F. Stress enhancement of craving during sobriety and the risk of relapse. Alcoholism: Clinical and Experimental Research. 2005;29:185–195. doi: 10.1097/01.alc.0000153544.83656.3c. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  33. Bremner J, Narayan M, Staib L, Southwick S, McGlashan T, Charney D. Neural correlates of memories of childhood sexual abuse in women with and without posttraumatic stress disorder. American Journal of Psychiatry. 1999;156:1787–1795. doi: 10.1176/ajp.156.11.1787. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI · Paper page
  34. Bremner J, Vythilingam M, Vermetten E, Southwick S, McGlashan T, Staib L, Soufer R, Charney D. Neural correlates of declarative memory for emotionally valenced words in women with posttraumatic stress disorder related to early childhood sexual abuse. Biological Psychiatry. 2003;53:879–889. doi: 10.1016/s0006-3223(02)01891-7. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  35. Britton J, Phan K, Taylor S, Fig L, Liberzon I. Corticolimbic blood flow in posttraumatic stress disorder during script-driven imagery. Biological Psychiatry. 2005;57:832–840. doi: 10.1016/j.biopsych.2004.12.025. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  36. Brody AL, Mandelkern M, Lee G, Smith E, Sadeghi M, Saxena S, Jarvik M, London ED. Attentuation of cue-induced cigarette craving and anterior cingulate cortex activation in bupropion-treated smokers: A preliminary study. Psychiatry Research. 2004;130:269–281. doi: 10.1016/j.pscychresns.2003.12.006. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  37. Brody AL, Mandelkern M, London ED, Childress AR, Lee G, Bota R, Ho M, Saxena S, Baxter LRJ, Madsen D, Jarvik M. Brain metabolic changes during cigarette craving. Archives General Psychiatry. 2002;59:1162–1172. doi: 10.1001/archpsyc.59.12.1162. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  38. Brown SM, Hariri AR. Neuroimaging studies of serotonin gene polymorphisms: exploring the interplay of genes, brain, and behavior. Cogn Affect Behav Neurosci. 2006;6:44–52. doi: 10.3758/cabn.6.1.44. [DOI] [PubMed] [Google Scholar] · DOI
  39. Bush G, Luu P, Posner MI. Cognitive and emotional influences in anterior cingulate cortex. Trends in Cognitive Sciences. 2000;4:215–222. doi: 10.1016/s1364-6613(00)01483-2. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  40. Butler G, Montgomery A. Impulsivity, risk taking, and recreational 'ecstasy' (MDMA) use. Drug and Alcohol Dependence. 2004;76:55–62. doi: 10.1016/j.drugalcdep.2004.04.003. [DOI] [PubMed] [Google Scholar] · DOI
  41. Butler G, Montgomery A. Subjective self-control and behavioral impulsivity coexist in anorexia nervosa. Eating Behaviors. 2005;6:221–227. doi: 10.1016/j.eatbeh.2004.11.002. [DOI] [PubMed] [Google Scholar] · DOI
  42. Capriles N, Rodaros D, Sorge RE, J S. A role for the prefrontal cortex in stress-and-cocaine-induced reinstatement of cocaine seeking in rats. Psychopharmacology (Berl) 2003;168:66–74. doi: 10.1007/s00213-002-1283-z. [DOI] [PubMed] [Google Scholar] · DOI
  43. Carter C, Krener P, Chaderjian M, Northcutt C, Wolfe V. Abnormal processing of irrelevant information in attention deficit hyperactivity disorder. Psychiatry Research. 1995;56:59–70. doi: 10.1016/0165-1781(94)02509-h. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  44. Cavedini P, Bassi T, Ubbiali A, Casolari A, Giordani S, Zorzi C, Bellodi L. Neuropsychological investigation of decision-making in anorexia nervosa. Psychiatry Research. 2004;127:259–266. doi: 10.1016/j.psychres.2004.03.012. [DOI] [PubMed] [Google Scholar] · DOI
  45. Chamberlain SR, Muller U, Robbins TW, Sahakian BJ. Neuropharmacological modulation of cognition. Curr Opin Neurol. 2006;19:607–612. doi: 10.1097/01.wco.0000247613.28859.77. [DOI] [PubMed] [Google Scholar] · DOI
  46. Chevalier H, Metz-Lutz MN, Segalowitz SJ. Impulsivity and control of inhibition in Benign Focal Childhood Epilepsy (BFCE) Brain Cogn. 2000;43:86–90. [PubMed] [Google Scholar]
  47. Childress A, Mozely PD, McElgin W, Fitzgerald J, Reivich M, O'Brien CP. Limbic activation during cue-induced cocaine craving. Am J Psychiatry. 1999;156:11–18. doi: 10.1176/ajp.156.1.11. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI · Paper page
  48. Clark L, Robbins TW, Ersche KD, Sahakian BJ. Reflection impulsivity in current and former substance users. Biol Psychiatry. 2006;60:515–522. doi: 10.1016/j.biopsych.2005.11.007. [DOI] [PubMed] [Google Scholar] · DOI
  49. Cloninger C, Sigvardsson S, Bowman M. Childhood personality predicts alcohol abuse in young adults. Alcohol Clin Exp Res. 1988;12:494–505. doi: 10.1111/j.1530-0277.1988.tb00232.x. [DOI] [PubMed] [Google Scholar] · DOI
  50. Coffey S, Saladin M, Drobes D, Brady K, BDansky B, Kilpatrick D. Trauma and substance cue reactivity in individuals with comorbid posttraumatic stress disorder and cocaine or alcohol dependence. Drug and Alcohol Dependence. 2002;65 doi: 10.1016/s0376-8716(01)00157-0. [DOI] [PubMed] [Google Scholar] · DOI
  51. Cools R, Robbins TW. Chemistry of the adaptive mind. Philos Transact A Math Phys Eng Sci. 2004;362:2871–2888. doi: 10.1098/rsta.2004.1468. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  52. Cox WM, Fadardi JS, Pothos EM. The addiction-stroop test: Theoretical considerations and procedural recommendations. Psychol Bull. 2006;132:443–476. doi: 10.1037/0033-2909.132.3.443. [DOI] [PubMed] [Google Scholar] · DOI
  53. Daglish M, Weinstein A, Malizia A, Wilson S, Melichar J, Britten S, Brewer C, Lingford-Hughes A, Myles J, Grasby P, Nutt D. Changes in regional cerebral blood flow elicited by craving memories in abstinent opiate-dependent subjects. American Journal of Psychiatry. 2001;158:1680–1686. doi: 10.1176/appi.ajp.158.10.1680. [DOI] [PubMed] [Google Scholar] · DOI
  54. Daglish M, Weinstein A, Malizia AL, Wilson S, Melichar JK, Lingford-Hughes A, Myles JS, Grasby P, Nutt DJ. Functional connectivity analysis of the neural circuits of opiate craving: "more" rather than "different". Neuroimage. 2003;20 doi: 10.1016/j.neuroimage.2003.07.025. [DOI] [PubMed] [Google Scholar] · DOI
  55. Dalgleish T, Yiend J, Bramham J, Teasdale J, Ogilvie A, Malhi G, Howard R. Neuropsychological processing associated with recovery from depression after stereotactic subaudate tractotomy. American Journal of Psychiatry. 2004;161:1913–1916. doi: 10.1176/ajp.161.10.1913. [DOI] [PubMed] [Google Scholar] · DOI
  56. Damasio AR. Descartes' Error: Emotion, Reason and the Human Brain. New York, NY: Crosset/Putnam; 1994. [Google Scholar]
  57. David S, Munafo M, Johansen-Berg H, Smith S, Rogers RD, Matthews P, Walton R. Ventral striatum/nucleus accumbens activation to smoking-related pictorial cues in smokers and nonsmokers: A functional magnetic resonance imaging study. Biological Psychiatry. 2005;58:488–494. doi: 10.1016/j.biopsych.2005.04.028. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  58. de Wit H, Richards JB. Dual determinants of drug use in humans: reward and impulsivity. Nebraska Symposium of Motivation. 2004;50:19–55. [PubMed] [Google Scholar]
  59. DeFrank RS, Jenkins C, Rose RM. A longitudinal investigation of the relationships among alcohol consumption, psychosocial factors, and blood pressure. Psychosomatic Medicine. 1987;49:236–249. doi: 10.1097/00006842-198705000-00003. [DOI] [PubMed] [Google Scholar] · DOI
  60. Di Chiara G, Bassareo V. Reward system and addiction: what dopamine does and doesn't do. Curr Opin Pharmacol. 2007;7:69–76. doi: 10.1016/j.coph.2006.11.003. [DOI] [PubMed] [Google Scholar] · DOI
  61. Di Chiara G, Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proceedings of the National Academy of Sciences. 1988;85:5274–5278. doi: 10.1073/pnas.85.14.5274. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI · Paper page
  62. Dimitrov M, Nakic M, Elpern-Waxman J, Granetz J, O'Grady J, Phipps M, Milne E, Logan G, Hasher L, Grafman J. Inhibitory attentional control in patients with frontal lobe damage. Brain Cognition. 2003;52:258–270. doi: 10.1016/s0278-2626(03)00080-0. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  63. Dougherty DM, Bjork JM, Moeller FG, Harper RA, Marsh DM, Mathias CW, Swann AC. Familial transmission of Continuous Performance Test behavior: attentional and impulsive response characteristics. J Gen Psychol. 2003;130:5–21. doi: 10.1080/00221300309601271. [DOI] [PubMed] [Google Scholar] · DOI
  64. Dougherty DM, Mathias CW, Marsh DM, Moeller FG, Swann AC. Suicidal behaviors and drug abuse: impulsivity and its assessment. Alcohol Depend Drug. 2004;(76 Suppl):S93–S105. doi: 10.1016/j.drugalcdep.2004.08.010. [DOI] [PubMed] [Google Scholar] · DOI
  65. Dougherty DM, Moeller FG, Steinberg JL, Marsh DM, Hines SE, Bjork JM. Alcohol increases commission error rates for a continuous performance test. Alcohol Clin Exp Res. 1999;23:1342–1351. [PubMed] [Google Scholar]
  66. Drexler K, Schweitzer JB, Quinn CK, Gross R, Ely TD, Muhammad F, Kilts CD. Neural activity related to anger in cocaine-dependent men: A possible link to violence and relapse. American Journal of Addiction. 2000;9:331–339. doi: 10.1080/105504900750047382. [DOI] [PubMed] [Google Scholar] · DOI
  67. Due D, Huettel S, Hall W, Rubin D. Activation in mesolimbic and visuospatial neural circuits elicited by smoking cues: Evidence from functional magnetic resonance imaging. American Journal of Psychiatry. 2002;159:954–960. doi: 10.1176/appi.ajp.159.6.954. [DOI] [PubMed] [Google Scholar] · DOI
  68. Dunn B, Dalgleish T, Lawrence A. The somatic marker hypothesis: A critical evaluation. Neuroscience Biobehavioral Review. doi: 10.1016/j.neubiorev.2005.07.001. In press. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  69. Dunnett SB, Meldrum A, Muir JL. Frontal-striatal disconnection disrupts cognitive performance of the frontal-type in the rat. Neuroscience. 2005;135:1055–1065. doi: 10.1016/j.neuroscience.2005.07.033. [DOI] [PubMed] [Google Scholar] · DOI
  70. Durston S, Thomas KM, Worden MS, Yang Y, Casey BJ. The effect of preceding context on inhibition: an event-related fMRI study. Neuroimage. 2002;16:449–453. doi: 10.1006/nimg.2002.1074. [DOI] [PubMed] [Google Scholar] · DOI
  71. Elliott R, Deakin B. Role of the orbitofrontal cortex in reinforcement processing and inhibitory control: Evidence from functional magnetic resonance imaging studies in healthy human subjects. International Review of Neurobiology. 2005;65:89–116. doi: 10.1016/S0074-7742(04)65004-5. [DOI] [PubMed] [Google Scholar] · DOI
  72. Everitt BJ, Dickinson A, Robbins TW. The neuropsychological basis of addictive behaviour. Brain Res Brain Res Rev. 2001;36:129–138. doi: 10.1016/s0165-0173(01)00088-1. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  73. Everitt B, Robbins TW. Neural systems of reinforcement for drug addiction: from actions to habits to compulsion. Nature Neuroscience. 2005;8:1481–1489. doi: 10.1038/nn1579. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  74. Everitt BJ, Wolf ME. Psychomotor stimulant addiction: a neural systems perspective. J Neurosci. 2002;22:3312–3320. doi: 10.1523/JNEUROSCI.22-09-03312.2002. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI · Paper page
  75. Fallgatter AJ, Wiesbeck GA, Weijers HG, Boening J, Strik WK. Event-related correlates of response suppression as indicators of novelty seeking in alcoholics. Alcohol Alcohol. 1998;33:475–481. doi: 10.1093/alcalc/33.5.475. [DOI] [PubMed] [Google Scholar] · DOI
  76. Fillmore M, Rush CR. Impaired inhibitory control of behavior in chronic cocaine users. Drug & Alcohol Dependence. 2002;66:265–273. doi: 10.1016/s0376-8716(01)00206-x. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  77. Fillmore MI, Rush CR. Alcohol effects on inhibitory and activational response strategies in the acquisition of alcohol and other reinforcers: priming the motivation to drink. J Stud Alcohol. 2001;62:646–656. doi: 10.15288/jsa.2001.62.646. [DOI] [PubMed] [Google Scholar] · DOI
  78. Fillmore MT, Rush CR, Hays L. Acute effects of oral cocaine on inhibitory control of behavior in humans. Drug Alcohol Depend. 2002;67 doi: 10.1016/s0376-8716(02)00062-5. [DOI] [PubMed] [Google Scholar] · DOI
  79. Fox HC, Hong KI, Siedlarz K, Sinha R. Enhanced Sensitivity to Stress and Drug/Alcohol Craving in Abstinent Cocaine-Dependent Individuals Compared to Social Drinkers. Neuropsychopharmacology. doi: 10.1038/sj.npp.1301470. In Press. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  80. Garavan H, Pankiewicz J, Bloom A, Cho J, Sperry L, Ross T, Salmeron B, Risinger R, Kelley D, Stein E. Cue-induced cocaine craving: neuroanatomical specificity for drug users and drug stimuli. American Journal of Psychiatry. 2000;157:1789–1798. doi: 10.1176/appi.ajp.157.11.1789. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  81. Garavan H, Ross T, Stein E. Right hemispheric dominance of inhibitory control: An event-related functional MRI study. Proc National Academy of Science. 1999;96:8301–8306. doi: 10.1073/pnas.96.14.8301. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI · Paper page
  82. George MS, Anton R, Bloomer C, Teneback C, Drobes D, Lorberbaum J, Nahas Z, DJ V. Activation of prefrontal cortex and anterior thalamus in alcoholic subjects on exposure to alcohol-specific cues. Archives General Psychiatry. 2001;58:345–352. doi: 10.1001/archpsyc.58.4.345. [DOI] [PubMed] [Google Scholar] · DOI
  83. Goeders NE. The impact of stress on addiction. European Neuropsychopharmacology. 2003;13:435–441. doi: 10.1016/j.euroneuro.2003.08.004. [DOI] [PubMed] [Google Scholar] · DOI
  84. Goeders NE. Stress and cocaine addiction. Journal of Pharmacology and Experimental Therapeutics. 2003;2301:785–789. doi: 10.1124/jpet.301.3.785. [DOI] [PubMed] [Google Scholar] · DOI
  85. Goldstein RZ, Volkow ND. Drug addiction and its underlying neurobiological basis: Neuroimaging for the involvement of the frontal cortex. American Journal of Psychiatry. 2002;159:1642–1652. doi: 10.1176/appi.ajp.159.10.1642. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI · Paper page
  86. Goldstein RZ, Tomasi D, Rajaram S, Cottone LA, Zhang L, Maloney T, Telang F, Alia-Klein N, Volkow ND. Role of the anterior cingulate and medial orbitofrontal cortex in processing drug cues in cocaine addiction. Neuroscience. 2007;144:1153–1159. doi: 10.1016/j.neuroscience.2006.11.024. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  87. Gottfried J, O'Doherty J, Dolan RJ. Appetitive and aversive olfactory learning in humans studied using event-related functional magnetic resonance imaging. Journal of Neuroscience. 2002;22:10829–10837. doi: 10.1523/JNEUROSCI.22-24-10829.2002. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  88. Grace AA. Disruption of cortical-limbic interaction as a substrate for comorbidity. Neurotox Res. 2006;10:93–101. doi: 10.1007/BF03033238. [DOI] [PubMed] [Google Scholar] · DOI
  89. Graybiel AM. The basal ganglia: learning new tricks and loving it. Curr. Opin. Neurobiol. 2005;15:638–644. doi: 10.1016/j.conb.2005.10.006. [DOI] [PubMed] [Google Scholar] · DOI
  90. Grigson PS, Twining RC. Cocaine-induced suppression of saccharin intake: a model of drug-induced devaluation of natural rewards. Behav Neurosci. 2002;116:321–333. [PubMed] [Google Scholar]
  91. Grusser S, Wrase J, Klein S, Hermann D, Smolka M, Ruf M, Weber-Fahr W, Flor H, Mann K, Braus D, Heinz A. Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics. Psychopharmacology (Berl) 2004;175:296–302. doi: 10.1007/s00213-004-1828-4. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  92. Haber SN. The primate basal ganglia: parallel and intergrative networks. J Chem. Neuroanat. 2003;26:317–330. doi: 10.1016/j.jchemneu.2003.10.003. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  93. Hariri AR, Drabant EM, Weinberger DR. Imaging genetics: perspectives from studies of genetically driven variation in serotonin function and corticolimbic affective processing. Biol Psychiatry. 2006;59:888–897. doi: 10.1016/j.biopsych.2005.11.005. [DOI] [PubMed] [Google Scholar] · DOI
  94. Heinz A, Siessmeier T, Wrase J, Hermann D, Klein S, Grusser S, Flor H, Braus D, Buchholz H, Grunder G, Schrechenberger M, Smolka M, Rosch F, Mann K, Bartenstein P. Correlation between dopamine D(2) receptors in the ventral striatum and central processing of alcohol cues and craving. American Journal of Psychiatry. 2004;161:1783–1789. doi: 10.1176/appi.ajp.161.10.1783. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  95. Henik A, Singh J, Beckley D, Rafal R. Disinhibition of automatic word reading in Parkinson's disease. Cortex. 1993;29:589–599. doi: 10.1016/s0010-9452(13)80283-3. [DOI] [PubMed] [Google Scholar] · DOI
  96. Hester R, Dixon V, Garavan H. A consistent attentional bias for drug-related material in active cocaine users across word and picture versions of the emotional Stroop task. Drug Alcohol Depend. 2006;81:251–257. doi: 10.1016/j.drugalcdep.2005.07.002. [DOI] [PubMed] [Google Scholar] · DOI
  97. Higley JD, Hasert MF, Suomi SJ, Linnoila M. Nonhuman primate model of alcohol abuse: Effects of early experience, personality, and stress on alcohol consumption. Proceedings of the National Academy of Sciences of the United States of America. 1991;88:7261–7265. doi: 10.1073/pnas.88.16.7261. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  98. Horvitz JC. Dopamine gating of glutamatergic sensorimotor and incentive motivational input signals to the striatum. Behav. Brain Res. 2002;137:65–74. doi: 10.1016/s0166-4328(02)00285-1. [DOI] [PubMed] [Google Scholar] · DOI
  99. Hyman S. Addiction to cocaine and amphetamine. Neuron. 1996;16:901–904. doi: 10.1016/s0896-6273(00)80111-7. [DOI] [PubMed] [Google Scholar] · DOI
  100. Hyman SE. Addiction: a disease of learning and memory. Am J Psychiatry. 2005;162:1414–1422. doi: 10.1176/appi.ajp.162.8.1414. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  101. Hyman SE, Malenka RC, Nestler EJ. Neural mechanisms of addiction: the role of reward-related learning and memory. Annu Rev Neurosci. 2006;29:565–598. doi: 10.1146/annurev.neuro.29.051605.113009. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  102. Ikeda A, Ohara S, Matsumoto R, Kunieda T, Nagamine T, Miyamoto S, Kohara N, Taki W, Hashimoto N, Shibasaki H. Role of primary sensorimotor cortices in generating inhibitory motor responses in humans. Brain. 2000;123:1710–1721. doi: 10.1093/brain/123.8.1710. [DOI] [PubMed] [Google Scholar] · DOI
  103. Ikemoto S, Panksepp J. The role of nucleus accumbens dopamine in motivated behaviors: a unifying interpretation with special reference to reward-seeking. Brain res Brain Res Reviews. 1999;31:6–41. doi: 10.1016/s0165-0173(99)00023-5. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  104. Jacobsen LK, Southwick SM, Kosten TR. Substance use disorders in patients with posttraumatic stress disorder: A review of the literature. American Journal of Psychiatry. 2001;158:1184–1190. doi: 10.1176/appi.ajp.158.8.1184. [DOI] [PubMed] [Google Scholar] · DOI
  105. Kalivas PW. Neurobiology of cocaine addiction: implications for new pharmacotherapy. Am J Addict. 2007;16:71–78. doi: 10.1080/10550490601184142. [DOI] [PubMed] [Google Scholar] · DOI
  106. Kalivas PW, Hu XT. Exciting inhibition in psychostimulant addiction. Trends Neurosci. 2006;29:610–616. doi: 10.1016/j.tins.2006.08.008. [DOI] [PubMed] [Google Scholar] · DOI
  107. Kalivas PW, McFarland K. Brain circuitry and the reinstatement of cocaine-seeking behavior. Psychopharmacology (Berl) 2003;168:44–56. doi: 10.1007/s00213-003-1393-2. [DOI] [PubMed] [Google Scholar] · DOI
  108. Kalivas P, Volkow ND, Seamans J. Unmanageable motivation in addiction: a pathology in prefrontal-accumbens glutamate transmission. Neuron. 2005;45:647–650. doi: 10.1016/j.neuron.2005.02.005. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  109. Kaufman J, Ross T, Stein E, Garavan H. Cingulate hypoactivity in cocaine users during a GO-NOGO task as revealed by event-related functional magnetic resonance imaging. Journal of Neuroscience. 2003;23:7839–7843. doi: 10.1523/JNEUROSCI.23-21-07839.2003. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  110. Kelley AE, Schiltz CA, Landry CF. Neural systems recruited by drug- and food-related cues: studies of gene activation in corticolimbic regions. Physiology and Behavior. 2005;86:11–14. doi: 10.1016/j.physbeh.2005.06.018. [DOI] [PubMed] [Google Scholar] · DOI
  111. Kilts CD, Gross RE, Ely TD, Drexler KPG. The neural correlates of cue-induced craving in cocaine-dependent women. American Journal of Psychiatry. 2004;161:233–241. doi: 10.1176/appi.ajp.161.2.233. [DOI] [PubMed] [Google Scholar] · DOI
  112. Kleeberg J, Bruggimann L, Annoni J, van Melle G, Bogousslavsky J, Schluep M. Altered decision-making in mulitple sclerosis: A sign of impaired emotional reactivity? Annals of Neurology. 2004;56:787–795. doi: 10.1002/ana.20277. [DOI] [PubMed] [Google Scholar] · DOI
  113. Knutson B, Fong G, Adams C, Varner J, Hommer D. Dissociation of reward anticipation and outcome with event-related fMRI. NeuroReport. 2001;12:3683–3687. doi: 10.1097/00001756-200112040-00016. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  114. Konishi S, Nakajima K, Uchida I, Sekihara K, Miyashita Y. No-go dominant brain activity in human inferior prefrontal cortex revealed by functional magnetic resonance imaging. Eur J Neurosci. 1998;10:1209–1213. doi: 10.1046/j.1460-9568.1998.00167.x. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  115. Koob GF. Neuroadaptive mechanisms of addiction: studies on the extended amygdala. Eur Neuropsychopharmacol. 2003;13:442–452. doi: 10.1016/j.euroneuro.2003.08.005. [DOI] [PubMed] [Google Scholar] · DOI
  116. Koob GF. The neurobiology of addiction: a neuroadaptational view relevant for diagnosis. Addiction. 2006;101 (Suppl. 1):23–30. doi: 10.1111/j.1360-0443.2006.01586.x. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  117. Koob GF, Ahmed SH, Boutrel B, Chen SA, Kenny PJ, Markou A, O'Dell LE, Parsons LH, Sanna PP. Neurobiological mechanisms in the transition from drug use to drug dependence. Neuroscience and Biobehavioral Reviews. 2004;27:739–749. doi: 10.1016/j.neubiorev.2003.11.007. [DOI] [PubMed] [Google Scholar] · DOI
  118. Koob GF, Le Moal M. Drug abuse: Hedonic homeostatic dysregulation. Science. 1997;278:52–58. doi: 10.1126/science.278.5335.52. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  119. Kosten TA, Miserendino MJD, Kehoe P. Enhanced acquisition of cocaine self-administration in adult rats with neonatal isolation stress experience. Brain Research. 2000;875:44–50. doi: 10.1016/s0006-8993(00)02595-6. [DOI] [PubMed] [Google Scholar] · DOI
  120. Lanius RA, Williamson PC, Densmore M, Boksman K, Gupta MA, Neufeld RW, Gati JS, Menon RS. Neural correlates of traumatic memories in posttraumatic stress disorder: A functional MRI investigation. American Journal of Psychiatry. 2001;158:1920–1922. doi: 10.1176/appi.ajp.158.11.1920. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  121. Levine B, Black S, Cheung G, Campbell A, O'Toole C, Schwartz M. Gambling task performance in traumatic brain injury: Relationships to injury severity, atrophy, lesion location, and cognitive and psychosocial outcome. Cognitive Behavioral Neurology. 2005;18:45–54. [PubMed] [Google Scholar]
  122. Levitt H. Transformed up-down methods in psychoaccoustics. Journal of Acoustic Society of America. 1970;49:467–477. [PubMed] [Google Scholar]
  123. Li C-S, Kosten TR, Sinha R. Sex differences in brain activation during stress imagery in abstinent cocaine users: A functional magnetic resonance imaging study. Biological Psychiatry. 2005a;57:487–494. doi: 10.1016/j.biopsych.2004.11.048. [DOI] [PubMed] [Google Scholar] · DOI
  124. Li C-SR, Huang C, Yan P, Paliwal P, Constable R, Sinha R. Neural correlates of impulse control during stop signal inhibition in cocaine dependent men. Neuropsychopharmacology. doi: 10.1038/sj.npp.1301568. In Press. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  125. Li CS, Kosten TR, Sinha R. Antisocial personality and stress-induced brain activation in cocaine-dependent patients. Neuroreport. 2006b;17:243–247. doi: 10.1097/01.wnr.0000199471.06487.a2. [DOI] [PubMed] [Google Scholar] · DOI
  126. Li C-SR, Mathalon DH, Krystal JH. Fore-period effect and stop signal processing time. Experimental Brain Research. 2005b;167:305–309. doi: 10.1007/s00221-005-0110-2. [DOI] [PubMed] [Google Scholar] · DOI
  127. Li C-SR, Milivojevic V, Kemp KA, Hong K, Sinha R. Performance monitoring and stop signal inhibition in abstinent patients with cocaine dependence. Drug and Alcohol Dependence. 2006c;85:205–212. doi: 10.1016/j.drugalcdep.2006.04.008. [DOI] [PubMed] [Google Scholar] · DOI
  128. Li CS, Milivojevic V, Constable RT, Sinha R. Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals. Psychiatry Res. 2005c;140:271–280. doi: 10.1016/j.pscychresns.2005.09.002. [DOI] [PubMed] [Google Scholar] · DOI
  129. Li CS, Sinha R. Alexithymia and stress-induced brain activation in cocaine-dependent men and women. J Psychiatry Neurosci. 2006;31:115–121. [PMC free article] [PubMed] [Google Scholar]
  130. Liberzon I, Britton J, Phan K. Neural correlates of traumatic recall in posttraumatic stress disorder. Stress. 2003;6:151–156. doi: 10.1080/1025389031000136242. [DOI] [PubMed] [Google Scholar] · DOI
  131. Liberzon I, Phan K. Brain-imaging studies of posttraumatic stress disorder. CNS Spectrums. 2003;8:641–650. doi: 10.1017/s109285290000883x. [DOI] [PubMed] [Google Scholar] · DOI
  132. Liddle PF, Kiehl KA, Smith AM. Event-related fMRI study of response inhibition. Hum Brain Mapp. 2001;12:100–109. doi: 10.1002/1097-0193(200102)12:2<100::AID-HBM1007>3.0.CO;2-6. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  133. Logan GD. Dagenbach DC, TH, editors. Inhibitory Processes in Attention,Memory and Language. Academic Press, San Diego. 1994:189–239. [Google Scholar]
  134. Logan J, Ding Y, Lin K, Pareto D, Fowler J, Biegon A. Modeling and analysis of PET studies with noreponephrine transporter ligands: the search for a reference region. Nucl Med Biol. 2005;32:531–542. doi: 10.1016/j.nucmedbio.2005.04.005. [DOI] [PubMed] [Google Scholar] · DOI
  135. Lu L, Koya E, Zhai H, Hope BT, Shaham Y. Role of ERK in cocaine addiction. Trends Neurosci. 2006;29:695–703. doi: 10.1016/j.tins.2006.10.005. [DOI] [PubMed] [Google Scholar] · DOI
  136. Maas LC, Lukas SE, Kaufman MJ, Weiss RD, Daniels SL, Rogers VW, Kukes TJ, Renshaw PF. Functional magnetic resonance imaging of human brain activation during cue-induced cocaine craving. American Journal of Psychiatry. 1998;155:124–126. doi: 10.1176/ajp.155.1.124. [DOI] [PubMed] [Google Scholar] · DOI
  137. Maia T, McClelland J. A reexamination of the evidence for the somatic marker hypotehsis: What partcicpants really know in the Iowa gambling task. Proceedings of the National Academy of Science. 2004;101:16075–16080. doi: 10.1073/pnas.0406666101. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  138. Maldonado R, Valverde O, Berrendero F. Involvement of the endocannabinoid system in drug addiction. Trends Neurosci. 2006;29:225–232. doi: 10.1016/j.tins.2006.01.008. [DOI] [PubMed] [Google Scholar] · DOI
  139. Martin-Soelch C, Leenders KL, Chevalley AF, Missimer J, Kunig G, Magyar S, Mino A, Schultz W. Reward mechanisms in the brain and their role in dependence: evidence from neurophysiological and neuroimaging studies. Brain Res Rev. 2001;36:139–149. doi: 10.1016/s0165-0173(01)00089-3. [DOI] [PubMed] [Google Scholar] · DOI
  140. Masse L, Tremblay R. Behavior of boys in kindergarten and the onset of substance use during adolescence. Archives of General Psychiatry. 1997;54:62–68. doi: 10.1001/archpsyc.1997.01830130068014. [DOI] [PubMed] [Google Scholar] · DOI
  141. McClernon F, Hiott F, Huettel S, Rose J. Abstinence-induced changes in self-report craving correlate with event-realted fMRI responses to smoking cues. Neurpsychopharmacology. 2005;30 doi: 10.1038/sj.npp.1300780. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI · Paper page
  142. McCullough LD, Salamone JD. Anxiogenic drugs beta-CCE and FG 7142 increase extracellular dopamine levels in nucleus accumbens. Psychopharmacology (Berl.) 1992;109:379–382. doi: 10.1007/BF02245888. [DOI] [PubMed] [Google Scholar] · DOI
  143. McCusker CG. Cognitive biases and addiction: an evolution in theory and method. Addiction. 2001;96:47–56. doi: 10.1046/j.1360-0443.2001.961474.x. [DOI] [PubMed] [Google Scholar] · DOI
  144. McGeorge AJ, Faull RM. The organization of the projection from the cerebral cortex to the striatum in the rat. Neuroscience. 1989;29:503–537. doi: 10.1016/0306-4522(89)90128-0. [DOI] [PubMed] [Google Scholar] · DOI
  145. Menon V, Adleman NE, White CD, Glover GH, Reiss AL. Error-related brain activation during a Go/NoGo response inhibition task. Human Brain Mapping. 2001;12:131–143. doi: 10.1002/1097-0193(200103)12:3<131::AID-HBM1010>3.0.CO;2-C. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  146. Meyer-Lindenberg A, Buckholtz JW, Kolachana B, R Hariri A, Pezawas L, Blasi G, Wabnitz A, Honea R, Verchinski B, Callicott JH, Egan M, Mattay V, Weinberger DR. Neural mechanisms of genetic risk for impulsivity and violence in humans. Proc Natl Acad Sci U S A. 2006;103:6269–6274. doi: 10.1073/pnas.0511311103. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI · Paper page
  147. Mintzer M, Stitzer ML. Cognitive impairment in methadone maintained patients. Drug Alcohol Dep. 2002;67:41–51. doi: 10.1016/s0376-8716(02)00013-3. [DOI] [PubMed] [Google Scholar] · DOI
  148. Moeller F, Barratt ES, Dougherty DM, Schmitz JM, Swann AC. Psychiatric aspects of impulsivity. Am J Psychiatry. 2001;158:1783–1793. doi: 10.1176/appi.ajp.158.11.1783. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  149. Moeller FG, Hasan KM, Steinberg JL, Kramer LA, Dougherty DM, Santos RM, Valdes I, Swann AC, Barratt ES, Narayana PA. Reduced anterior corpus callosum white matter integrity is related to increased impulsivity and reduced discriminability in cocaine-dependent subjects: diffusion tensor imaging. Neuropsychopharmacology. 2005;30:610–617. doi: 10.1038/sj.npp.1300617. [DOI] [PubMed] [Google Scholar] · DOI
  150. Monterosso J, Ainslie G. The behavioral economics of will in recovery from addiction. Drug Alcohol Depend. doi: 10.1016/j.drugalcdep.2006.09.004. In Press. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  151. Morgan MJ. Recreational use of "ecstasy" (MDMA) is associated with elevated impulsivity. Neuropsychopharmacology. 1998;19:252–264. doi: 10.1016/S0893-133X(98)00012-8. [DOI] [PubMed] [Google Scholar] · DOI
  152. Morgan MJ, McFie L, Fleetwood H, Robinson JA. Ecstasy (MDMA): are the psychological problems associated with its use reversed by prolonged abstinence? Psychopharmacology (Berl) 2002;159:294–303. doi: 10.1007/s002130100907. [DOI] [PubMed] [Google Scholar] · DOI
  153. Morgan MJ, Impallomeni LC, Pirona A, Rogers RD. Elevated impulsivity and impaired decision-making in abstinent Ecstasy (MDMA) users compared to polydrug and drug-naïve controls. Neuropsychopharmacology. 2006;31:1562–1573. doi: 10.1038/sj.npp.1300953. [DOI] [PubMed] [Google Scholar] · DOI
  154. Mulvihill LE, Skilling TA, Vogel-Sprott M. Alcohol and the ability to inhibit behavior in men and women. J Stud Alcohol. 1997;58:600–605. doi: 10.15288/jsa.1997.58.600. [DOI] [PubMed] [Google Scholar] · DOI
  155. Myrick H, Anton R, Li X, Henderson S, Drobes D, Voronin K, George M. Differential brain activity in alcoholics and social drinkers to alcohol cues: Relationship to craving. Neuropsychopharmacology. 2004;29:393–402. doi: 10.1038/sj.npp.1300295. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  156. Nachev P, Rees G, Parton A, Kennard C, Husain M. Volition and conflict in human medial frontal cortex. Current Biology. 2005;15:122–128. doi: 10.1016/j.cub.2005.01.006. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI
  157. Nagai Y, Critchley H, Featherstone E, Trimble M, Dolan R. Activity in ventromedial prefrontal cortex covaries with sympathetic skin conductance level: A physiological account of a "default mode" of brain function. Neuroimage. 2004;22:243–251. doi: 10.1016/j.neuroimage.2004.01.019. [DOI] [PubMed] [Google Scholar] · DOI
  158. Najavits LM, Gastfriend DR, Barber JP, Reif S, Muenz LR, Blaine J, Frank A, Crits-Christoph P, Thase M, Weiss RD. Cocaine dependence with and without PTSD among subjects in the National Institute on Drug Abuse Collaborative Cocaine Treatment Study. American Journal of Psychiatry. 1998;155:214–219. doi: 10.1176/ajp.155.2.214. [DOI] [PubMed] [Google Scholar] · DOI
  159. Naqvi NH, Rudrauf D, Damasio H, Bechara A. Damage to the insula disrupts addiction to cigarette smoking. Science. 2007;315:531–534. doi: 10.1126/science.1135926. [DOI] [PMC free article] [PubMed] [Google Scholar] · DOI · Paper page
  160. Nuechterlein KH, Dawson ME. Information processing and attentional functioning in the developmental course of schizophrenic disorder. Schizophr Bull. 1984;10:160–203. doi: 10.1093/schbul/10.2.160. [DOI] [PubMed] [Google Scholar] · DOI
  161. O'Doherty J, Deichmann R, Crithcley H, Dolan R. Neural responses during anticipation of a primary taste reward. Neuron. 2002;33:815–826. doi: 10.1016/s0896-6273(02)00603-7. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  162. Oosterlaan J, Sergeant JA. Inhibition in ADHD, aggressive, and anxious children: a biologically based model of child psychopathology. J Abnorm Child Psychol. 1996;24:19–36. doi: 10.1007/BF01448371. [DOI] [PubMed] [Google Scholar] · DOI
  163. Oswald LM, Wong DF, McCaul M, Zhou Y, Kuwabara H, Choi L, Brasic J, Wand GS. Relationships among ventral striatal dopamine release, cortisol secretion, and subjective responses to amphetamine. Neuropsychopharmacology. 2005;30:821–832. doi: 10.1038/sj.npp.1300667. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  164. Oswald LM, Wong DF, McCaul ME, Zhou Y, Kuwabara H, Wand GS. Glucocorticoids, stress, impulsivity and ventral striatal dopamine release. Alcoholism: Clinical and Experimental Research. 2006;30(6):281A. doi: 10.1111/j.1530-0277.2006.00130.x. [DOI] [PubMed] [Google Scholar] · DOI
  165. Ouimette PC, Moos RH, Finney JW. Two-year mental health service use and course of remission in patients with substance use and posttraumatic stress disorders. J Stud Alcohol. 2000;61:247–253. doi: 10.15288/jsa.2000.61.247. [DOI] [PubMed] [Google Scholar] · DOI
  166. Paris J, Zelkowitz P, Guzder J, Joseph S, Feldman R. Neuropsychological factors associated with borderline pathology in children. Journal of the American Academy of Child and Adolescent Psychiatry. 1999;38:770–774. [PubMed] [Google Scholar]
  167. Petrovic P, Carlsson K, Petersson K, Hansson P, Ingvar M. Context-dependent deactivation of the amygdala during pain. Jounral of Cognitive Neuroscience. 2004;16:1289–1301. doi: 10.1162/0898929041920469. [DOI] [PubMed] [Google Scholar] · DOI
  168. Pezawas L, Meyer-Lindenberg A, Drabant E, Verchinski B, Munoz K, LKolachana B, Egan M, Mataay V, Hariri A, Weinberger D. 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: A genetic susceptibility mechanism for depression. Nature Neuroscience. 2005;8:828–834. doi: 10.1038/nn1463. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  169. Phan KL, Fitzgerald DA, Nathan P, Moore G, Uhde T, Tancer M. Neural substrates for voluntary suppression of negative affect: A functional magnetic resonance imaging study. Biological Psychiatry. 2005;57:210–219. doi: 10.1016/j.biopsych.2004.10.030. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  170. Piazza PV, Le Moal M. Pathophysiological basis of vulnerability to drug abuse: Role of an interaction between stress, glucocorticoids, and dopaminergic neurons. Annual Review of Pharmacology and Toxicology. 1996;36:359–378. doi: 10.1146/annurev.pa.36.040196.002043. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  171. Piazza PV, Deminiere JM, Le Moal M, Simon H. Factors that predict individual vulnerability to amphetamine self-administration. Science. 1989;245:1511–1513. doi: 10.1126/science.2781295. [DOI] [PubMed] [Google Scholar] · DOI
  172. Piazza PV, Le Moal M. The role of stress in drug self-administration. Trends in Pharmacological Sciences. 1998;19:67–74. doi: 10.1016/s0165-6147(97)01115-2. [DOI] [PubMed] [Google Scholar] · DOI
  173. Quirk GJ, Gehlert DR. Inhibition of the amygdala: key to pathological states? Annals of the New York Academy of Science. 2003;985:263–272. doi: 10.1111/j.1749-6632.2003.tb07087.x. [DOI] [PubMed] [Google Scholar] · DOI
  174. Rabbit PMA. Errors and error correction in choice-response tasks. J Exp Psychol. 1966;71:264–272. doi: 10.1037/h0022853. [DOI] [PubMed] [Google Scholar] · DOI
  175. Rauch SL, Whalen PJ, Shin LM, McInerney SC, Macklin M, Lasko N, Orr S, Pitman R. Exaggerated amygdala response to masked facial stimuli in posttraumatic stress disorder: A functional MRI study. Society of Biological Psychiatry. 2000;47:769–776. doi: 10.1016/s0006-3223(00)00828-3. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  176. Robinson TE, Berridge KC. The psychology and neurobiology of addiction: an incentive-sensitization view. Addiction. 2000;95 Suppl 2:S91–S117. doi: 10.1080/09652140050111681. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  177. Rubia K, Oosterlaan J, Sergeant JA, Brandeis D, von Leeuwen T. Inhibitory dysfunction in hyperactive boys. Behav Brain Res. 1998;94:25–32. doi: 10.1016/s0166-4328(97)00166-6. [DOI] [PubMed] [Google Scholar] · DOI
  178. Rubia K, Russell T, Overmeyer S, Brammer MJ, Bullmore ET, Sharma T, Simmons A, Williams SC, Giampietro V, Andrew CM, Taylor E. Mapping motor inhibition: conjunctive brain activation across different versions of go/no-go and stop tasks. Neuroimage. 2001;13:250–261. doi: 10.1006/nimg.2000.0685. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  179. Rubia K, Smith AB, Brammer MJ, Taylor E. Right inferior prefrontal cortex mediates response inhibition while mesial prefrontal cortex isresponsible for error detection. Neuroimage. 2003;20:351–358. doi: 10.1016/s1053-8119(03)00275-1. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  180. Rubia K, Smith AB, Brammer MJ, Toone B, Taylor E. Abnormal brain activation during inhibition and error detection in medication-naïve adolescents. Am J Psychiatry. 2005;162:1067–1075. doi: 10.1176/appi.ajp.162.6.1067. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  181. Salamone JD, Cousins MS, Snyder BJ. Behavioral functions of nucleus accumbens dopamine: empirical and conceptual problems with the anhedonia hypothesis. Neuroscience Biobehavioral Reviews. 1997;21:341–359. doi: 10.1016/s0149-7634(96)00017-6. [DOI] [PubMed] [Google Scholar] · DOI
  182. Schachar R, Mota VL, Logan GD, Tannock R, Klim P. Deficient inhibitory control in attention deficit hyperactivity disorder. J Abnorm Child Psychol. 1995;23:411–437. doi: 10.1007/BF01447206. [DOI] [PubMed] [Google Scholar] · DOI
  183. Schneider F, Habel U, Wagner M, Franke P, Salloum J, Shah N, Toni I, Sulzbach C, Honig K, Maier W, Gaebel W, Zilles K. Subcortical correlates of craving in recently abstinent alcoholic patients. American Journal of Psychiatry. 2001;158:1075–1083. doi: 10.1176/appi.ajp.158.7.1075. [DOI] [PubMed] [Google Scholar] · DOI
  184. Sell L, Morris JS, Bearn J, Frackowiak RS, Friston KJ, Dolan RJ. Activation of reward circuitry in human opiate addicts. European Journal of Neuroscience. 1999;11:1042–1048. doi: 10.1046/j.1460-9568.1999.00522.x. [DOI] [PubMed] [Google Scholar] · DOI
  185. Sell L, Morris JS, Bearn J, Frackowiak RS, Friston KJ, Dolan RJ. Neural responses associated with cue evoked emotional states and heroin in opiate addicts. Drug & Alcohol Dependence. 2000;60:207–216. doi: 10.1016/s0376-8716(99)00158-1. [DOI] [PubMed] [Google Scholar] · DOI
  186. Self DW, Choi KH. Extinction-induced neuroplasticity attenuates stress-induced cocaine seeking: a state-dependent learning hypothesis. Stress. 2004;7:145–155. doi: 10.1080/10253890400012677. [DOI] [PubMed] [Google Scholar] · DOI
  187. Shaham Y, Shalev U, Lu L, de Wit H, Stewart J. The reinstatement model of drug relapse: history, methodology and major findings. Psychopharmacology(Berl.) 2003;168:3–20. doi: 10.1007/s00213-002-1224-x. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  188. Shin LM, Rauch SL, Pitman RK. Amygdala, medial prefrontal cortex, and hippocampal function in PTSD. Ann N Y Acad Sci. 2006;1071:67–79. doi: 10.1196/annals.1364.007. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  189. Sinha R. Stress and drug abuse. In: Steckler T, N.H.K., Reul JMHM, editors. Handbook of Stress and the Brain. Part 2 Stress: Integrative and Clinical Aspects. vol. 15. Elsevier, Amsterdam; 2005. pp. 333–356. [Google Scholar]
  190. Sinha R, Catapano D, O'Malley S. Stress-induced craving and stress response in cocaine dependent individuals. Psychopharmacology (Berl) 1999;142:343–351. doi: 10.1007/s002130050898. [DOI] [PubMed] [Google Scholar] · DOI
  191. Sinha R, Fuse T, Renee-Aubin l, O'Malley SS. Psychological stress, drug cues and cocaine craving. Psychopharmacol. 2000;152:140–148. doi: 10.1007/s002130000499. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  192. Sinha R, Lacadie C, Skudlarski P, Fulbright RK, Rounsaville BJ, Kosten TR, Wexler BE. Neural activity associated with stress-induced cocaine craving: A functional magnetic imaging study. Psychopharmacol. 2005;183:171–180. doi: 10.1007/s00213-005-0147-8. [DOI] [PubMed] [Google Scholar] · DOI
  193. Sinha R, Lacadie C, Skudlarski P, Wexler BE. Neural circuits underlying emotional distress in humans. Annals of the New York Academy of Sciences. 2004;1032:254–257. doi: 10.1196/annals.1314.032. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  194. Sinha R, Li C-SR. Imaging stress and cue-induced drug and alcohol craving: Association to relapse and clinical implications. Drug and Alcohol Review. 2007;26:25–31. doi: 10.1080/09595230601036960. [DOI] [PubMed] [Google Scholar] · DOI · Paper page
  195. Sinha R, Talih M, Malison R, Anderson GA, Cooney N, Kreek MJ. Hypothalamic-pituitary-adrenal axis and sympatho-adreno-medullary responses during stress-induced and drug cue-induced cocaine craving states. Psychopharmacology. 2003;170:62–72. doi: 10.1007/s00213-003-1525-8. [DOI] [PubMed] [Google Scholar] · DOI
  196. Sorg BA, Kalivas PW. Effects of cocaine and footshock stress on extracellular dopamine levels in the ventral striatum. Brain Res. 1991;559:29–36. doi: 10.1016/0006-8993(91)90283-2. [DOI] [PubMed] [Google Scholar] · DOI
  197. Stewart J. Pathways to relapse: factors controlling the reinitiation of drug seeking after abstinence. Lincoln, NE: University of Nebraska Press; 2003. [PubMed] [Google Scholar]
  198. Stewart JA, Tannock R. Inhibitory control differences following mild head injury. Brain Cogn. 1999;41:411–416. doi: 10.1006/brcg.1999.1141. [DOI] [PubMed] [Google Scholar] · DOI
  199. Swann AC, Bjork JM, Moeller FG, Dougherty DM. Two models of impulsivity: relationship to personality traits and psychopathology. Biol Psychiatry. 2002;51:988–994. doi: 10.1016/s0006-3223(01)01357-9. [DOI] [PubMed] [Google Scholar] · DOI
  200. Tapert S, Brown G, Baratta M, Brown S. fMRI BOLD response to alcohol stimuli in alcohol dependent young women. Addictive Behaviors. 2004;29:33–50. doi: 10.1016/j.addbeh.2003.07.003. [DOI] [PubMed] [Google Scholar] · DOI

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Cited by

Sorted by citations

Authors
Li, C.-S. R., & Sinha, R.
Affiliations
Yale University (US)
Corresponding author
Li, Chiang-shan Ray
ORCID
Venue
Neuroscience & Biobehavioral Reviews
Publisher
Elsevier BV
Published
2008-01
Volume
32
Issue
3
Pages
581-597
ISSN
0149-7634 (ISSN-L)
DOI
10.1016/j.neubiorev.2007.10.003
PMC
PMC2263143
OpenAlex
W1970452940
Cited by
345
References
54
Citations by year
2026: 5 · 2025: 10 · 2024: 6 · 2023: 18 · 2022: 9 · 2021: 15 · 2020: 37 · 2019: 18 · 2018: 15 · 2017: 17 · 2016: 33 · 2015: 24 · 2014: 30 · 2013: 22 · 2012: 18
FWCI
1.06
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Neuroscience & Biobehavioral Reviews (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • Yale University
  • National Institutes of Health
  • National Institute on Drug Abuse (K02 DA17232, P50DA016556, K02DA017232, R03DA022395, K12DA014038, R01-DA11077, K12-DA-14038, K02DA026990, R01DA011077, P50-DA16556)
  • National Center for Research Resources (RR024139, UL1RR024139)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords
inhibitory control, ventromedial prefrontal cortex, anterior cingulate cortex, amygdala, striatum, compulsive drug seeking, drug addiction, neural pathways
MeSH terms
Central Nervous System Stimulants, Brain Mapping, Frontal Lobe, Humans, Inhibition, Psychological, Limbic System, Motivation, Neural Pathways, Stress, Psychological, Substance-Related Disorders

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