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Treatment of psychiatric illness by stereotactic cingulotomy
Abstract
The treatment of 198 psychiatrically disabled patients with stereotactic cingulotomy was evaluated prospectively for a mean follow-up of 8.6 years. Patients with major affective disorders and anxiety disorders fared the best, with a return to normal functioning in the majority. Patients with obsessive-compulsive disorders, schizophrenia, and personality disorders improved less predictably, with an uneven improvement in functioning that required active ongoing psychiatric treatment. Low mortality and morbidity, a reduction of violent behavior, a possible reduction of suicidal risk, and a lessening of the intractable suffering of chronic psychiatric illness all indicate that cingulotomy can be an effective, safe treatment for patients with affective disorders that are unresponsive to all other forms of therapy.
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“A prospective analysis of 198 cases with bilateral cingulum bundle lesions (Ballantine et al., 1987) pointed to lasting improvements in approximately half of those treated for obsessive compulsive disorders (OCD)”
From The cingulum bundle: Anatomy, function, and dysfunction (2018) · cites this paper as Ballantine et al., 1987
In the citing paper
“with slightly better outcomes for anxiety disorders and affective disorders, including depression (Ballantine et al., 1987; Shields et al., 2008).”
From The cingulum bundle: Anatomy, function, and dysfunction (2018) · cites this paper as Ballantine et al., 1987
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Metadata
- Authors
- Ballantine, H. T., Bouckoms, A. J., Thomas, E. K., & Giriunas, I. E.
- Affiliations
- Harvard University (US)
- Massachusetts General Hospital (US)
- Corresponding author
- Ballantine, H.Thomas
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 1987-07
- Volume
- 22
- Issue
- 7
- Pages
- 807-819
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2064542914
- Cited by
- 328
- References
- 13
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 6 · 2023: 3 · 2022: 6 · 2021: 8 · 2020: 7 · 2019: 4 · 2018: 21 · 2017: 5 · 2016: 6 · 2015: 10 · 2014: 12 · 2013: 18 · 2012: 11
- FWCI
- 3.68
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
- Keywords
- mental illness, mood disorders, anxiety disorders, obsessive-compulsive disorder, schizophrenia, personality disorders, treatment outcomes, long-term follow-up, violent behavior, suicide risk, refractory psychiatric disorders
- MeSH terms
- Adolescent, Adult, Aged, Anxiety Disorders, Mental Disorders, Child, Female, Follow-Up Studies, Gyrus Cinguli, Humans, Male, Middle Aged, Personality Disorders, Psychomotor Performance, Schizophrenia, Social Adjustment, Stereotaxic Techniques, Mood Disorders
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