Effects of a D1 and a D2 dopamine antagonist on the self-administration of cocaine and piribedil by Rhesus monkeys

Woolverton, William L.

doi:10.1016/0091-3057(86)90553-8

Cited by 182Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology ResearchSchizophrenia research and treatment

Effects of a D1 and a D2 dopamine antagonist on the self-administration of cocaine and piribedil by Rhesus monkeys

Woolverton, William L.·1986·Pharmacology Biochemistry and Behavior

DOI 10.1016/0091-3057(86)90553-8

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Abstract

Rhesus monkeys were surgically prepared with chronic intravenous catheters and allowed to self-administer the indirect dopamine (DA) agonist cocaine (0.03 or 0.1 mg/kg/inj) or the direct D2 agonist piribedil (0.1 or 0.2 mg/kg/inj) on a fixed-ratio 10 schedule of drug delivery during daily 2 hour experimental sessions. When responding was stable, they were injected IV with SCH 23390, a selective D1 antagonist (0.003-0.3 mg/kg, 30 min pre-session) or pimozide, a selective D2 antagonist (0.003-0.3 mg/kg, 2 hours pre-session). Intermediate doses of pimozide generally increased self-administration of cocaine or piribedil, though increases in piribedil self-administration were more reliable. In contrast, intermediate doses of SCH 23390 either did not affect or decreased cocaine and piribedil self-administration. High doses of each antagonist decreased the rate of self-administration of each compound and produced catalepsy. The selective increase in responding maintained by cocaine or piribedil following pimozide pretreatment suggests a role for a D2-like receptor in psychomotor stimulant self-administration.

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D2R is necessary for reward and incentive learning and maintenance of reward- and incentive-related responding, and rats will self-administer drugs that activate these receptors.
“D2R is also necessary for reward and incentive learning, as well as maintenance of reward- and incentive-related responding, and rats will readily self-administer drugs that activate these receptors (Woolverton et al 1984; Sanger 1986; Woolverton 1986; Hoffman et al 1988; for an early review of the roles of D1R and D2R in reward and reinforcement, see Beninger et al 1989).”
From The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction (2012) · cites this paper as Woolverton 1986

Multiple receptors for dopamine
Kebabian, J. W., & Calne, D. B. (1979) · Nature · doi:10.1038/277093a0 · Cited by 3,742 · see citing works
Brain dopamine receptors.
Seeman, P. M. (1980) · Pharmacological Reviews · doi:10.1016/s0031-6997(25)06839-5 · Cited by 1,888 · see citing works
SCH 23390, a potential benzazepine antipsychotic with unique interactions on dopaminergic systems.
Iorio, L. C., Barnett, A., Leitz, F. H., Houser, V. P., & Korduba, C. A. (1983) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)21599-3 · Cited by 896 · see citing works
SCH 23390—The first selective dopamine D-1 antagonist
Hyttel, J. (1983) · European Journal of Pharmacology · doi:10.1016/0014-2999(83)90381-3 · Cited by 740 · see citing works
On the role of ascending catecholaminergic systems in intravenous self-administration of cocaine
Roberts, D. C. S., Corcoran, M. E., & Fibiger, H. C. (1977) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(77)90084-3 · Cited by 728 · see citing works
Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide, but not with the noradrenergic blockers phentolamine or phenoxybenzamine.
de Wit, H., & Wise, R. A. (1977) · Canadian Journal of Psychology / Revue canadienne de psychologie · doi:10.1037/h0081662 · Cited by 491 · see citing works
Disruption of cocaine self-administration following 6-hydroxydopamine lesions of the ventral tegmental area in rats
Roberts, D. C. S., & Koob, G. F. (1982) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(82)90469-5 · Cited by 448 · see citing works
Pharmacological effects of a specific dopamine D-1 antagonist SCH 23390 in comparison with neuroleptics
Christensen, A. V., Arnt, J., Hyttel, J., Larsen, J. ‐., & Svendsen, O. (1984) · Life Sciences · doi:10.1016/0024-3205(84)90607-6 · Cited by 373 · see citing works
Dopaminergic behaviour stereospecifically promoted by the D1 agonist R-SK & F 38393 and selectively blocked by the D1 antagonist SCH 23390
Molloy, A. G., & Waddington, J. L. (1984) · Psychopharmacology · doi:10.1007/bf00427697 · Cited by 352 · see citing works
Induction of oral dyskinesias in naive rats by D1 stimulation
Rosengarten, H., Schweitzer, J. W., & Friedhoff, A. J. (1983) · Life Sciences · doi:10.1016/0024-3205(83)90155-8 · Cited by 250 · see citing works
Intravenous self-administration of dopamine receptor agonists by rhesus monkeys.
Woolverton, W. L., Goldberg, L. I., & Ginos, J. Z. (1984) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)21719-0 · Cited by 204 · see citing works
Self-citation
Amphetamine-type reinforcement by dopaminergic agonists in the rat
Yokel, R. A., & Wise, R. A. (1978) · Psychopharmacology · doi:10.1007/bf00427393 · Cited by 181 · see citing works
The effects of chlorpromazine on psychomotor stimulant self-administration in the Rhesus monkey
Wilson, M. C., & Schuster, C. R. (1972) · Psychopharmacology · doi:10.1007/bf00422098 · Cited by 181 · see citing works
Evidence that apomorphine and pergolide induce rotation in rats by different actions on D1 and D2 receptor sites
Herrera‐Marschitz, M., & Ungerstedt, U. (1984) · European Journal of Pharmacology · doi:10.1016/0014-2999(84)90587-9 · Cited by 125 · see citing works
Separation of peripheral dopamine receptors by a selective DA1 antagonist, SCH 23390.
Goldberg, L. I., Glock, D., Kohli, J. D., & Barnett, A. (1984) · Hypertension · doi:10.1161/01.hyp.6.2_pt_2.i25 · Cited by 84 · see citing works
The effects of stimulants and depressants on cocaine self-administration behavior in the Rhesus monkey
Wilson, M. C., & Schuster, C. R. (1973) · Psychopharmacology · doi:10.1007/bf00421274 · Cited by 53 · see citing works
Cocaine, d-amphetamine, and pentobarbital effects on responding maintained by food or cocaine in rhesus monkeys
Herling, S., Downs, D. A., & Woods, J. H. (1979) · Psychopharmacology · doi:10.1007/bf00427508 · Cited by 39 · see citing works
CHLORPROMAZINE-AND HALOPERIDOL-INDUCED CHANGES IN SOME BEHAVIORAL EFFECTS OF COCAINE AND AMPHETAMINE
Woods, J. H., Herling, S., & Winger, G. D. (1978) · Elsevier eBooks · doi:10.1016/b978-1-4832-8322-7.50190-4 · Cited by 20 · see citing works
PHARMACOLOGICAL MODIFICATION OF COCAINE AND APOMORPHINE SELF-ADMINISTRATION IN THE SQUIRREL MONKEY
GILL, C. A., Holz, W. C., Zirkle, C. L., & Hill, H. F. (1978) · Elsevier eBooks · doi:10.1016/b978-1-4832-8322-7.50189-8 · Cited by 18 · see citing works

Flagged first, then by citations

2 of the 21 references couldn’t be matched to a known paper.

Sorted by citations

Drug abuse: hedonic homeostatic dysregulation
Koob, G. F., & Moal, M. L. (1997) · Science · doi:10.1126/science.278.5335.52 · Cited by 2,535 · see citing works
Cellular and molecular mechanisms of drug dependence
Koob, G. F., & Bloom, F. E. (1988) · Science · doi:10.1126/science.2903550 · Cited by 2,070 · see citing works
The dopamine hypothesis of the reinforcing properties of cocaine
Kuhar, M. J., Ritz, M. C., & Boja, J. W. (1991) · Trends in Neurosciences · doi:10.1016/0166-2236(91)90141-g · Cited by 989 · see citing works
Brain Reward Circuitry
Wise, R. A. (2002) · Neuron · doi:10.1016/s0896-6273(02)00965-0 · Cited by 881 · see citing works
The mesolimbic dopamine system: The final common pathway for the reinforcing effect of drugs of abuse?
Pierce, R. C., & Kumaresan, V. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.04.016 · Cited by 913 · see citing works
The role of dopamine in drug abuse viewed from the perspective of its role in motivation
Chiara, G. D. (1995) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(95)01118-i · Cited by 624 · see citing works
Dopamine Signaling in reward-related behaviors
Baik, J. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00152 · Cited by 534 · see citing works
Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses
Xu, M., Moratalla, R., Gold, L. H., Hiroi, N., Koob, G. F., Graybiel, A. M., & Tonegawa, S. (1994) · Cell · doi:10.1016/0092-8674(94)90557-6 · Cited by 484 · see citing works
Reinforcing effects of psychostimulants in humans are associated with increases in brain dopamine and occupancy of D(2) receptors.
Volkow, N. D., Wang, G.-J., Fowler, J., Logan, J., Gatley, S., Wong, C., Hitzemann, R., & Pappas, N. (1999) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)35115-8 · Cited by 434 · see citing works
The neurocircuitry of addiction: an overview
Feltenstein, M. W., & See, R. E. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.51 · Cited by 421 · see citing works
Involvement of cAMP-dependent protein kinase in the nucleus accumbens in cocaine self-administration and relapse of cocaine-seeking behavior
Self, D. W., Genova, L. M., Hope, B. T., Barnhart, W. J., Spencer, J. J., & Nestler, E. J. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-05-01848.1998 · Cited by 325 · see citing works
The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction
Burkett, J. P., & Young, L. J. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2794-x · Cited by 307 · see citing works
“D2R is also necessary for reward and incentive learning, as well as maintenance of reward- and incentive-related responding, and rats will readily self-administer drugs that activate these receptors (Woolverton et al. 1984; Sanger 1986; Woolverton 1986; Hoffman et al. 1988; for an early review of the roles of D1R and…”
Dopamine D1-like Receptors and Reward-related Incentive Learning
Beninger, R. J. (1998) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(97)00019-5 · Cited by 299 · see citing works
Effects of the dopamine D-1 antagonist SCH 23390 microinjected into the accumbens, amygdala or striatum on cocaine self-administration in the rat
Caine, S. B., Heinrichs, S. C., Coffin, V. L., & Koob, G. F. (1995) · Brain Research · doi:10.1016/0006-8993(95)00598-k · Cited by 286 · see citing works
Selective dopamine antagonists reduce nicotine self-administration
Corrigall, W. A., & Coen, K. M. (1991) · Psychopharmacology · doi:10.1007/bf02244174 · Cited by 276 · see citing works
Controversies in translational research: drug self-administration.
Haney, M., & Spealman, R. (2008) · Psychopharmacology · doi:10.1007/s00213-008-1079-x · Cited by 270 · see citing works
Monoamine transporters and psychostimulant addiction
Howell, L. L., & Kimmel, H. L. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.08.003 · Cited by 249 · see citing works
Effects of increasing the magnitude of an alternative reinforcer on drug choice in a discrete-trials choice procedure
Nader, M. A., & Woolverton, W. L. (1991) · Psychopharmacology · doi:10.1007/bf02244304 · Cited by 253 · see citing works
Self-citation
Critical assessment of how to study addiction and its treatment: Human and non-human animal models
O’Brien, C. P., & Gardner, E. L. (2005) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.06.018 · Cited by 221 · see citing works
Parameters of self-administration of cocaine in rats under a progressive-ratio schedule
Depoortère, R., Li, D. H., Lane, J. D., & Emmett‐Oglesby, M. W. (1993) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(93)90503-l · Cited by 215 · see citing works
Cocaine-induced alterations in dopamine receptor signaling: Implications for reinforcement and reinstatement
Anderson, S. M., & Pierce, R. C. (2005) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2004.12.004 · Cited by 200 · see citing works
Pharmacotherapies for Treatment of Cocaine Abuse: Preclinical Aspects
Carroll, F. I., Howell, L. L., & Kuhar, M. J. (1999) · Journal of Medicinal Chemistry · doi:10.1021/jm9706729 · Cited by 203 · see citing works
Drugs acting on brain dopamine receptors: A conceptual re-evaluation five years after the first selective D-1 antagonist
Waddington, J. L., & O’Boyle, K. M. (1989) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(89)90046-6 · Cited by 203 · see citing works
High Dose Pimozide Does Not Block Amphetamine-Induced Euphoria in Normal Volunteers
Brauer, L. H. (1997) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(96)00240-7 · Cited by 194 · see citing works
Baclofen Attenuates the Reinforcing Effects of Cocaine in Rats
Roberts, D. C. S. (1996) · Neuropsychopharmacology · doi:10.1016/0893-133x(96)00002-4 · Cited by 193 · see citing works
Effects of ecopipam, a selective dopamine D1 antagonist, on smoked cocaine self-administration by humans
Haney, M., Ward, A. S., Foltin, R. W., & Fischman, M. W. (2001) · Psychopharmacology · doi:10.1007/s002130100725 · Cited by 187 · see citing works
Differential behavioral responses to dopaminergic stimulation of nucleus accumbens subregions in the rat
Swanson, C. J., Heath, S., Stratford, T. R., & Kelley, A. E. (1997) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(97)00043-9 · Cited by 176 · see citing works
Effects of selective D1 and D2 dopamine antagonists on cocaine self-administration in the rat
Hubner, C. B., & Moreton, J. E. (1991) · Psychopharmacology · doi:10.1007/bf02244301 · Cited by 167 · see citing works
A neuroendocrine role in cocaine reinforcement
Goeders, N. E. (1997) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(97)00027-9 · Cited by 168 · see citing works
Buprenorphine Suppresses Cocaine Self-Administration by Rhesus Monkeys
Mello, N. K., Mendelson, J. H., Bree, M. P., & Lukas, S. E. (1989) · Science · doi:10.1126/science.2772637 · Cited by 165 · see citing works
Opiate antagonists reduce cocaine but not nicotine self-administration
Corrigall, W. A., & Coen, K. M. (1991) · Psychopharmacology · doi:10.1007/bf02244173 · Cited by 156 · see citing works
The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats
Paterson, N. E., & Markou, A. (2004) · Psychopharmacology · doi:10.1007/s00213-004-2070-9 · Cited by 155 · see citing works
Locating Reward Cue at Response Manipulandum (CAM) Induces Symptoms of Drug Abuse
Tomie, A. (1996) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(95)00023-2 · Cited by 138 · see citing works
The D1 agonists SKF 82958 and SKF 77434 are self-administered by rats
Self, D. W., & Stein, L. (1992) · Brain Research · doi:10.1016/0006-8993(92)90155-3 · Cited by 130 · see citing works
What We Have Learned about Addiction from Animal Models of Drug Self‐Administration
Gardner, E. L. (2000) · American Journal on Addictions · doi:10.1080/105504900750047355 · Cited by 130 · see citing works
Cocaine self-administration is increased by both D1 and D2 dopamine antagonists
Corrigall, W. A., & Coen, K. M. (1991) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(91)90168-2 · Cited by 130 · see citing works
Drug abuse and bipolar disorder: comorbidity or misdiagnosis?
Brown, E. S., Suppes, T. M., Adinoff, B. H., & Thomas, N. R. (2001) · Journal of Affective Disorders · doi:10.1016/s0165-0327(00)00169-5 · Cited by 130 · see citing works
The dopamine D-1 receptor antagonist SCH 23390 injected into the dorsolateral bed nucleus of the stria terminalis decreased cocaine reinforcement in the rat
Epping-Jordan, M. P., Markou, A., & Koob, G. F. (1998) · Brain Research · doi:10.1016/s0006-8993(97)01190-6 · Cited by 131 · see citing works
The effects of a D1 and a D2 dopamine antagonist on behavior maintained by cocaine or food
Woolverton, W. L., & Virus, R. M. (1989) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(89)90019-1 · Cited by 129 · see citing works
Self-citation
Blockade of striatal dopamine transporters by intravenous methylphenidate is not sufficient to induce self-reports of “high”
Volkow, N. D., Wang, G.-J., Fowler, J. S., Gatley, S. J., Logan, J., Ding, Y.-S., Dewey, S. L., Hitzemann, R., Gifford, A. N., & Pappas, N. R. (1999) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37918-2 · Cited by 125 · see citing works
Sensitization and Tolerance in Psychostimulant Self-Administration
Schenk, S., & Partridge, B. (1997) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(96)00447-9 · Cited by 123 · see citing works
Functional significance of mesolimbic dopamine
Kiyatkin, E. A. (1995) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(95)00029-1 · Cited by 122 · see citing works
Alterations in offspring behavior induced by chronic prenatal cocaine dosing
Smith, R. F., Mattran, K. M., Kurkjian, M. F., & Kurtz, S. L. (1989) · Neurotoxicology and Teratology · doi:10.1016/0892-0362(89)90082-2 · Cited by 119 · see citing works
Pharmacological regulation of intravenous cocaine and heroin self-administration in rats: A variable dose paradigm
Gerber, G. J., & Wise, R. A. (1989) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(89)90192-5 · Cited by 118 · see citing works
Bilateral intra-accumbens self-administration ofd-amphetamine: Antagonism with intra-accumbens SCH-23390 and sulpiride
Phillips, G. D., Robbins, T. W., & Everitt, B. J. (1994) · Psychopharmacology · doi:10.1007/bf02249339 · Cited by 116 · see citing works
The emerging roles of human trace amines and human trace amine-associated receptors (hTAARs) in central nervous system
Khan, M. Z., & nawaz, W. (2016) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2016.07.002 · Cited by 116 · see citing works
Dopamine receptor agonists, partial agonists and psychostimulant addiction
Pulvirenti, L., & Koob, G. F. (1994) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(94)90158-9 · Cited by 114 · see citing works
Receptor subtype-specific dopaminergic agents and conditioned behavior
Beninger, R. J., Hoffman, D. C., & Mazurski, E. J. (1989) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(89)80019-3 · Cited by 109 · see citing works
Behavioral effects of cocaine and dopaminergic strategies for preclinical medication development
Platt, D. M., Rowlett, J. K., & Spealman, R. D. (2002) · Psychopharmacology · doi:10.1007/s00213-002-1137-8 · Cited by 107 · see citing works
COCAINE VERSUS FOOD CHOICE PROCEDURE IN RATS: ENVIRONMENTAL MANIPULATIONS AND EFFECTS OF AMPHETAMINE
Thomsen, M., Barrett, A. C., Negus, S. S., & Caine, S. B. (2013) · Journal of the Experimental Analysis of Behavior · doi:10.1002/jeab.15 · Cited by 101 · see citing works
Dopamine D-1 and D-2 receptors in relation to reward and performance: A case for the D-1 receptor as a primary site of therapeutic action of neuroleptic drugs
Miller, R. J., Wickens, J. R., & Beninger, R. J. (1990) · Progress in Neurobiology · doi:10.1016/0301-0082(90)90005-2 · Cited by 100 · see citing works
Cocaine modulation of central monoaminergic neurotransmission
Pitts, D. K., & Marwah, J. (1987) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(87)90147-x · Cited by 99 · see citing works
Self-administration of D1 receptor agonists by squirrel monkeys
Grech, D. M., Spealman, R. D., & Bergman, J. (1996) · Psychopharmacology · doi:10.1007/bf02249407 · Cited by 96 · see citing works
Involvement of Accumbal Glycine Receptors in the Regulation of Voluntary Ethanol Intake in the Rat
Molander, A., L??f, E., Stomberg, R., Ericson, M., & S�derpalm, B. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000150009.78622.e0 · Cited by 93 · see citing works
Isolation rearing impairs the reinforcing efficacy of intravenous cocaine or intra-accumbensd-amphetamine: impaired response to intra-accumbens D1 and D2/D3 dopamine receptor antagonists
Phillips, G. D., Howes, S. R., Whitelaw, R. B., Robbins, T. W., & Everitt, B. J. (1994) · Psychopharmacology · doi:10.1007/bf02245085 · Cited by 90 · see citing works
Dopamine ligands and the stimulus effects of amphetamine: animal models versus human laboratory data
Brauer, L. H., Goudie, A. J., & de Wit, H. (1997) · Psychopharmacology · doi:10.1007/s002130050207 · Cited by 91 · see citing works
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Woolverton, W. L. (1987) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(87)90618-6 · Cited by 88 · see citing works
Self-citation
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Pitts, D. K., Udom, C., & Marwah, J. (1987) · Life Sciences · doi:10.1016/0024-3205(87)90573-x · Cited by 89 · see citing works
Parallel Roles for Dopamine in Pathological Gambling and Psychostimulant Addiction
Zack, M. H., & Poulos, C. X. (2009) · Current Drug Abuse Reviews · doi:10.2174/1874473710902010011 · Cited by 84 · see citing works
Lesions of central serotonin systems affect responding on a progressive ratio schedule reinforced either by intravenous cocaine or by food
Roberts, D. C. S., Loh, E. A., Baker, G. B., & Vickers, G. (1994) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(94)90473-1 · Cited by 84 · see citing works
Self -Administration of Psychomotor Stimulants Using Progressive Ratio Schedules of Reinforcement
Roberts, D. C. S., & Richardson, N. R. (2003) · Humana Press eBooks · doi:10.1385/0-89603-217-5:233 · Cited by 84 · see citing works
Inhibition by MK-801 of cocaine-induced sensitization, conditioned place preference, and dopamine-receptor supersensitivity in mice
Kim, H.-S., Park, W.-K., Jang, C., & Oh, S. (1996) · Brain Research Bulletin · doi:10.1016/0361-9230(96)00006-8 · Cited by 82 · see citing works
Neural Substrates and Circuits of Drug AddictionPreprint
Feltenstein, M. W., See, R. E., & Fuchs, R. A. (2020) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a039628 · Cited by 88 · see citing works
Fluctuations in nucleus accumbens dopamine during cocaine self-administration behavior: An in vivo electrochemical study
Kiyatkin, E. A., & Stein, E. A. (1995) · Neuroscience · doi:10.1016/0306-4522(94)00436-9 · Cited by 80 · see citing works
Pharmacotherapy of cocaine abuse: Preclinical development
Witkin, J. M. (1994) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(94)90042-6 · Cited by 80 · see citing works
Receptor Subtypes in Opioid and Stimulant Reward
Self, D. W., & Stein, L. (1992) · Pharmacology & Toxicology · doi:10.1111/j.1600-0773.1992.tb00435.x · Cited by 79 · see citing works
Selective D1 and D2 dopamine agonists produce opposing effects in place conditioning but not in conditioned taste aversion learning
Hoffman, D. C., & Beninger, R. J. (1988) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(88)90302-4 · Cited by 77 · see citing works
Neurochemical interactions of cocaine with dopaminergic systems
Galloway, M. P. (1988) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(88)90137-x · Cited by 77 · see citing works
Effects of dopaminergic agents on alcohol consumption by rats in a limited access paradigm
Linseman, M. A. (1990) · Psychopharmacology · doi:10.1007/bf02244405 · Cited by 75 · see citing works
Tolerance to self-administration of cocaine in rats: time course and dose-response determination using a multi-dose method
Emmett‐Oglesby, M. W., Peltier, R., Depoortère, R., Pickering, C. L., Hooper, M. L., Gong, Y. H., & Lane, J. D. (1993) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(93)90089-9 · Cited by 75 · see citing works
Subtypes of dopamine receptors involved in the mechanism of reinforcement
Nakajima, S. (1989) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(89)80020-x · Cited by 73 · see citing works
Drug Discrimination in Methamphetamine-Trained Monkeys: Agonist and Antagonist Effects of Dopaminergic Drugs
Tidey, J. W., & Bergman, J. (1998) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)37511-1 · Cited by 72 · see citing works
Dopamine mediation of positive reinforcing effects of amphetamine in stimulant naïve healthy volunteers: results from a large cohort.
Abi-Dargham, A., Kegeles, L., Martinez, D., Innis, R., & Laruelle, M. (2003) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2003.08.007 · Cited by 73 · see citing works
Increased operant responding for ethanol in male C57BL/6J mice: specific regulation by the ERK1/2, but not JNK, MAP kinase pathway
Faccidomo, S., Besheer, J., Stanford, P. C., & Hodge, C. W. (2009) · Psychopharmacology · doi:10.1007/s00213-008-1444-9 · Cited by 64 · see citing works
Presynaptic G Protein-Coupled Receptors: Gatekeepers of Addiction?
Johnson, K. A., & Lovinger, D. M. (2016) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2016.00264 · Cited by 66 · see citing works
Self-administration of GBR 12909 on a fixed ratio and progressive ratio schedule in rats
Roberts, D. C. S. (1993) · Psychopharmacology · doi:10.1007/bf02245524 · Cited by 63 · see citing works
Self-administration of the D1 agonist SKF 82958 is mediated by D1, not D2, receptors
Self, D. W., Belluzzi, J. D., Kossuth, S. R., & Stein, L. (1996) · Psychopharmacology · doi:10.1007/bf02246638 · Cited by 64 · see citing works
Cocaine and central monoaminergic neurotransmission: A review of electrophysiological studies and comparison to amphetamine and antidepressants
Pitts, D. K., & Marwah, J. (1988) · Life Sciences · doi:10.1016/0024-3205(88)90425-0 · Cited by 62 · see citing works
Dopamine D4 Receptors in Psychostimulant Addiction
Ciano, P. D., Grandy, D. K., & Foll, B. L. (2014) · Advances in pharmacology · doi:10.1016/b978-0-12-420118-7.00008-1 · Cited by 58 · see citing works
Preclinical research on cocaine self-administration: environmental determinants and their interaction with pharmacological treatment
LeSage, M. G., Stafford, D. A., & Glowa, J. R. (1999) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(99)00015-9 · Cited by 58 · see citing works
Dopamine D1 receptors in the nucleus accumbens: involvement in the reinforcing effect of tegmental stimulation
Kurumiya, S., & Nakajima, S. (1988) · Brain Research · doi:10.1016/0006-8993(88)91095-5 · Cited by 57 · see citing works
Lethal effects of cocaine are reduced by the dopamine-1 receptor antagonist SCH 23390 but not by haloperidol
Witkin, J. M., Goldberg, S. R., & Katz, J. L. (1989) · Life Sciences · doi:10.1016/0024-3205(89)90366-4 · Cited by 56 · see citing works
Antagonism of behavioral effects of cocaine by selective dopamine receptor blockers
Spealman, R. D. (1990) · Psychopharmacology · doi:10.1007/bf02253732 · Cited by 55 · see citing works
Cocaine-induced changes in extracellular dopamine determined by microdialysis in awake squirrel monkeys
Czoty, P., Justice, J. B., & Howell, L. (2000) · Psychopharmacology · doi:10.1007/s002130050054 · Cited by 57 · see citing works
A single injection of either flupenthixol decanoate or haloperidol decanoate produces long-term changes in cocaine self-administration in rats
Richardson, N. R. (1994) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(94)90005-1 · Cited by 52 · see citing works
Dopamine D1 and D3 receptor polypharmacology as a potential treatment approach for substance use disorder
Galaj, E., Ewing, S., & Ranaldi, R. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.03.020 · Cited by 47 · see citing works
Dopamine D3 receptor ligands for drug addiction treatment
Foll, B. L., Collo, G., Rabiner, E. A., Boileau, I., Pich, E. M., & Sokoloff, P. (2014) · Progress in brain research · doi:10.1016/b978-0-444-63425-2.00011-8 · Cited by 48 · see citing works
Olanzapine attenuates the reinforcing effects of cocaine
Meil, W. M., & Schechter, M. (1997) · European Journal of Pharmacology · doi:10.1016/s0014-2999(97)01351-4 · Cited by 46 · see citing works
Brain stimulation and morphine reward deficits in dopamine D2 receptor-deficient mice
Elmer, G. I., Pieper, J. O., Levy, J., Rubinstein, M., Low, M. J., Grandy, D. K., & Wise, R. A. (2005) · Psychopharmacology · doi:10.1007/s00213-005-0051-2 · Cited by 44 · see citing works
Systems Level Neuroplasticity in Drug AddictionPreprint
Feltenstein, M. W., & See, R. E. (2013) · Cold Spring Harbor Perspectives in Medicine · doi:10.1101/cshperspect.a011916 · Cited by 43 · see citing works
Effects of bromocriptine and desipramine on behavior maintained by cocaine or food presentation in rhesus monkeys
Kleven, M. S., & Woolverton, W. L. (1990) · Psychopharmacology · doi:10.1007/bf02244128 · Cited by 43 · see citing works
Self-citation
Effects of buspirone and gepirone on IV cocaine self-administration in rhesus monkeys
Gold, L. H., & Balster, R. L. (1992) · Psychopharmacology · doi:10.1007/bf02245114 · Cited by 42 · see citing works
Recent methods for measuring dopamine D3 receptor occupancy in vivo: importance for drug development
Foll, B. L., Wilson, A. A., Graff, A., Boileau, I., & Ciano, P. D. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2014.00161 · Cited by 41 · see citing works
Effects of bromocriptine pretreatment on subjective and physiological responses to IV cocaine
Kumor, K. M., Sherer, M. A., & Jaffe, J. H. (1989) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(89)90478-4 · Cited by 41 · see citing works
Comparative Behavioral Pharmacology of Cocaine and the Selective Dopamine Uptake Inhibitor RTI-113 in the Squirrel Monkey
Howell, L. L., Czoty, P. W., Kuhar, M. J., & Carroll, F. I. (2000) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)35321-2 · Cited by 40 · see citing works
Role of D1 and D2 dopamine receptors in the behavioral effects of cocaine
Spealman, R. D., Bergman, J., Madras, B. K., Kamien, J. B., & Melia, K. F. (1992) · Neurochemistry International · doi:10.1016/0197-0186(92)90228-j · Cited by 40 · see citing works
D1 receptor hypersensitivity in mice with low striatal D2 receptors facilitates select cocaine behaviors
Dobbs, L. K., Kaplan, A. R., Bock, R., Phamluong, K., Shin, J. H., Bocarsly, M. E., Eberhart, L., Dorit Ron, A., & Alvarez, V. A. (2018) · Neuropsychopharmacology · doi:10.1038/s41386-018-0286-3 · Cited by 39 · see citing works
Restructuring of basal ganglia circuitry and associated behaviors triggered by low striatal D2 receptor expression: implications for substance use disorders
Dobbs, L. K., Lemos, J. C., & Alvarez, V. A. (2016) · Genes Brain & Behavior · doi:10.1111/gbb.12361 · Cited by 39 · see citing works
Serotonergic modulation of the discriminative-stimulus effects of cocaine in squirrel monkeys
Schama, K. F., Howell, L. L., & Byrd, L. D. (1997) · Psychopharmacology · doi:10.1007/s002130050316 · Cited by 38 · see citing works
Neuronal spike activity in rat nucleus accumbens during cocaine self-administration under different fixed-ratio schedules
Chang, J., Paris, J. M., Sawyer, S. F., Kirillov, A. B., & Woodward, D. J. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00144-3 · Cited by 38 · see citing works

Antagonism of cocaine self-administration by selective dopamine D1 and D2 antagonists
Bergman, J., Kamien, J. B., & Spealman, R. D. (1990) · Behavioural Pharmacology · doi:10.1097/00008877-199001040-00009 · Cited by 9 · see citing works
The D1 dopamine receptor antagonist SCH 23390 increases cocaine self-administration in the rat
Koob, G. F., Le, H. T., & Creese, I. (1987) · Neuroscience Letters · doi:10.1016/0304-3940(87)90451-4 · Cited by 274 · see citing works
Cocaine self-administration is increased by both D1 and D2 dopamine antagonists
Corrigall, W. A., & Coen, K. M. (1991) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(91)90168-2 · Cited by 130 · see citing works
Self-administration of D1 receptor agonists by squirrel monkeys
Grech, D. M., Spealman, R. D., & Bergman, J. (1996) · Psychopharmacology · doi:10.1007/bf02249407 · Cited by 96 · see citing works
PHARMACOLOGICAL MODIFICATION OF COCAINE AND APOMORPHINE SELF-ADMINISTRATION IN THE SQUIRREL MONKEY
GILL, C. A., Holz, W. C., Zirkle, C. L., & Hill, H. F. (1978) · Elsevier eBooks · doi:10.1016/b978-1-4832-8322-7.50189-8 · Cited by 18 · see citing works

Authors: Woolverton, W. L.
Affiliations: University of Chicago (US)
Corresponding author: Woolverton, William L.
Venue: Pharmacology Biochemistry and Behavior
Publisher: Elsevier BV
Published: 1986-03
Volume: 24
Issue: 3
Pages: 531-535
ISSN: 0091-3057 (ISSN-L)
DOI: 10.1016/0091-3057(86)90553-8
OpenAlex: W1977382144
Cited by: 181
References: 21
Citations by year: 2024: 1 · 2022: 1 · 2021: 1 · 2020: 3 · 2019: 1 · 2018: 2 · 2016: 6 · 2015: 1 · 2014: 7 · 2013: 7 · 2012: 3
FWCI: 3.50
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Pharmacology Biochemistry and Behavior (publishedVersion)
PubMed (publishedVersion)
Funders: Massachusetts Department of Agricultural Resources
National Institute on Drug Abuse (DA00250)
Janssen Pharmaceuticals
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Keywords: cocaine self-administration, piribedil, dopamine D1 receptor, dopamine D2 receptor, dopamine antagonists, pimozide, SCH 23390, psychostimulants, rhesus monkeys, catalepsy, fixed-ratio schedules
MeSH terms: Animals, Benzazepines, Cocaine, Drug Interactions, Female, Macaca mulatta, Male, Pimozide, Piperazines, Piribedil, Receptors, Dopamine, Self Administration, Antipsychotic Agents

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Effects of a D1 and a D2 dopamine antagonist on the self-administration of cocaine and piribedil by Rhesus monkeys

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