Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension)

2018 ESC/ESH Guidelines for the management of arterial hypertension

Williams, B., Mancia, G., Spiering, W., Agabiti Rosei, E., Azizi, M., Burnier, M., Clement, D. L., Coca, A., de Simone, G., Dominiczak, A., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy339 · Cited by 10,286

Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38

(1998) · BMJ · doi:10.1136/bmj.317.7160.703 · Cited by 6,683

Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the hypertension optimal treatment (HOT) randomised trial

Hansson, L., Zanchetti, A., Carruthers, S. G., Dahlöf, B., Elmfeldt, D., Julius, S., Ménard, J., Rahn, K. H., Wedel, H., & Westerling, S. (1998) · The Lancet · doi:10.1016/s0140-6736(98)04311-6 · Cited by 5,728

2013 ESH/ESC Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)

Mancia, G., Fagard, R., Narkiewicz, K., Redón, J., Zanchetti, A., Böhm, M., Christiaens, T., Cifkova, R., De Backer, G., Dominiczak, A., et al. (2013) · Journal of Hypertension · doi:10.1097/01.hjh.0000431740.32696.cc · Cited by 5,655

Cardiovascular morbidity and mortality in the losartan intervention for endpoint reduction in hypertension study (LIFE): A randomised trial against atenolol

Dahlöf, B., Devereux, R. B., Kjeldsen, S. E., Julius, S., Beevers, G., de Faire, U., Fyhrquist, F., Ibsen, H., Kristiansson, K., Lederballe-Pedersen, O., et al. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08089-3 · Cited by 5,407

2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension: Endorsed by the International Society of Hypertension (ISH) and the European Renal Association (ERA)

Mancia, G., Kreutz, R., Brunström, M., Burnier, M., Grassi, G., Januszewicz, A., Muiesan, M. L., Tsioufis, K., Agabiti-Rosei, E., Algharably, E. A. E., et al. (2023) · Journal of Hypertension · doi:10.1097/hjh.0000000000003480 · Cited by 3,473

Treatment of hypertension in patients 80 years of age or older

Beckett, N. S., Peters, R., Fletcher, A. E., Staessen, J. A., Liu, L., Dumitrascu, D., Stoyanovsky, V., Antikainen, R. L., Nikitin, Y., Anderson, C., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0801369 · Cited by 3,092

Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension

Staessen, J. A., Fagard, R., Thijs, L., Celis, H., Arabidze, G. G., Birkenhäger, W. H., Bulpitt, C. J., de Leeuw, P. W., Dollery, C. T., Fletcher, A. E., et al. (1997) · The Lancet · doi:10.1016/s0140-6736(97)05381-6 · Cited by 2,989

2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension

Williams, B., Mancia, G., Spiering, W., Agabiti Rosei, E., Azizi, M., Burnier, M., Clement, D. L., Coca, A., de Simone, G., Dominiczak, A., et al. (2018) · Journal of Hypertension · doi:10.1097/hjh.0000000000001940 · Cited by 2,885

Long-term trends in the incidence of and survival with heart failure

Levy, D., Kenchaiah, S., Larson, M. G., Benjamin, E. J., Kupka, M. J., Ho, K. K. L., Murabito, J. M., & Vasan, R. S. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020265 · Cited by 2,152

The progression from hypertension to congestive heart failure

Levy, D. (1996) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1996.03530440037034 · Cited by 2,155

Reappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force document

Mancia, G., Laurent, S., Agabiti-Rosei, E., Ambrosioni, E., Burnier, M., Caulfield, M. J., Cifkova, R., Clément, D., Coca, A., Dominiczak, A., et al. (2009) · Journal of Hypertension · doi:10.1097/hjh.0b013e328333146d · Cited by 1,643

Metformin: An Old Drug for the Treatment of Diabetes But a New Drug for the Protection of the Endothelium

Kinaan, M., Ding, H., & Triggle, C. R. (2015) · Medical Principles and Practice · doi:10.1159/000381643 · Cited by 1,515

Prevention of coronary heart disease in clinical practice Recommendations of the Second Joint Task Force of European and other Societies on Coronary Prevention

Second Joint Task Force of European (1998) · European Heart Journal · doi:10.1053/euhj.1998.1243 · Cited by 1,131

A Comparison of Outcomes with Angiotensin-Converting–Enzyme Inhibitors and Diuretics for Hypertension in the Elderly

Wing, L. M. H., Reid, C. M., Ryan, P., Beilin, L. J., Brown, M. A., Jennings, G. L. R., Johnston, C. I., McNeil, J. J., Macdonald, G. J., Marley, J. E., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa021716 · Cited by 1,130

The UKPDS risk engine: a model for the risk of coronary heart disease in Type II diabetes (UKPDS 56)

STEVENS, R. J., KOTHARI, V., ADLER, A. I., & STRATTON, I. M. (2001) · Clinical Science · doi:10.1042/cs20000335 · Cited by 1,084

Effects of antihypertensive-drug class on interindividual variation in blood pressure and risk of stroke: a systematic review and meta-analysis

Webb, A. J., Fischer, U., Mehta, Z., & Rothwell, P. M. (2010) · The Lancet · doi:10.1016/s0140-6736(10)60235-8 · Cited by 729

Hypertension Is Related to Cognitive Impairment: A 20-Year Follow-up of 999 Men

Kilander, L., Nyman, H., Boberg, M., Hansson, L., & Lithell, H. (1998) · Hypertension · doi:10.1161/01.hyp.31.3.780 · Cited by 630

Controlled Trial of Continuous Positive Airway Pressure in Obstructive Sleep Apnea and Heart Failure

Mansfield, D. R., Gollogly, N. C., Kaye, D. M., Richardson, M., Bergin, P., & Naughton, M. T. (2004) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200306-752oc · Cited by 617

Atenolol in hypertension: is it a wise choice?

Carlberg, B., Samuelsson, O., & Lindholm, L. H. (2004) · The Lancet · doi:10.1016/s0140-6736(04)17355-8 · Cited by 562

Expert consensus document on ?-adrenergic receptor blockersThe Task Force on Beta-Blockers of the European Society of Cardiology

(2004) · European Heart Journal · doi:10.1016/j.ehj.2004.06.002 · Cited by 557

The Exclusion of the Elderly and Women From Clinical Trials in Acute Myocardial Infarction

Gurwitz, J. H. (1992) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1992.03490110055029 · Cited by 532

Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): randomised controlled trial

Poole-Wilson, P. A., Lubsen, J., Kirwan, B.-A., van Dalen, F. J., Wagener, G., Danchin, N., Just, H., Fox, K. A., Pocock, S. J., Clayton, T. C., et al. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16980-8 · Cited by 511

Comparative Antihypertensive Effects of Hydrochlorothiazide and Chlorthalidone on Ambulatory and Office Blood Pressure

Ernst, M. E., Carter, B. L., Goerdt, C. J., Steffensmeier, J. J. G., Phillips, B. B., Zimmerman, M. B., & Bergus, G. R. (2006) · Hypertension · doi:10.1161/01.hyp.0000203309.07140.d3 · Cited by 433

Effects of blood pressure lowering on outcome incidence in hypertension. 1. Overview, meta-analyses, and meta-regression analyses of randomized trials

Thomopoulos, C., Parati, G., & Zanchetti, A. (2014) · Journal of Hypertension · doi:10.1097/hjh.0000000000000378 · Cited by 388

Effect of antihypertensive treatment at different blood pressure levels in patients with diabetes mellitus: systematic review and meta-analyses

Brunström, M., & Carlberg, B. (2016) · BMJ · doi:10.1136/bmj.i717 · Cited by 375

Long-term effect of diuretic-based therapy on fatal outcomes in subjects with isolated systolic hypertension with and without diabetes

Kostis, J. B., Wilson, A. C., Freudenberger, R. S., Cosgrove, N. M., Pressel, S. L., & Davis, B. R. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2004.08.059 · Cited by 325

Elevated systolic blood pressure and risk of cardiovascular and renal disease: overview of evidence from observational epidemiologic studies and randomized controlled trials

He, J., & Whelton, P. K. (1999) · American Heart Journal · doi:10.1016/s0002-8703(99)70312-1 · Cited by 325

Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia

McGuinness, B., Todd, S., Passmore, P., & Bullock, R. (2009) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004034.pub3 · Cited by 315

Current evidence supporting the role of diuretics in heart failure: a meta analysis of randomised controlled trials

Faris, R., Flather, M., Purcell, H., Henein, M., Poole-Wilson, P., & Coats, A. (2002) · International Journal of Cardiology · doi:10.1016/s0167-5273(01)00600-3 · Cited by 260

Cardiovascular Protection Using Beta-Blockers

Bangalore, S., Messerli, F. H., Kostis, J. B., & Pepine, C. J. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.04.060 · Cited by 233

Effects of blood-pressure-lowering treatment on outcome incidence in hypertension: 10 – Should blood pressure management differ in hypertensive patients with and without diabetes mellitus? Overview and meta-analyses of randomized trials

Thomopoulos, C., Parati, G., & Zanchetti, A. (2017) · Journal of Hypertension · doi:10.1097/hjh.0000000000001276 · Cited by 206

Dementia and Disability Outcomes in Large Hypertension Trials: Lessons Learned from the Systolic Hypertension in the Elderly Program (SHEP) Trial

Di Bari, M., Pahor, M., Franse, L. V., Shorr, R. I., Wan, J. Y., Ferrucci, L., Somes, G. W., & Applegate, W. B. (2001) · American Journal of Epidemiology · doi:10.1093/aje/153.1.72 · Cited by 193

Cardiovascular drug therapy in the elderly: benefits and challenges

Fleg, J. L., Aronow, W. S., & Frishman, W. H. (2011) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2010.162 · Cited by 186

Treatment of hypertension in patients 80 years and older: the lower the better? A meta-analysis of randomized controlled trials

Bejan-Angoulvant, T., Saadatian-Elahi, M., Wright, J. M., Schron, E. B., Lindholm, L. H., Fagard, R., Staessen, J. A., & Gueyffier, F. (2010) · Journal of Hypertension · doi:10.1097/hjh.0b013e328339f9c5 · Cited by 178

Disease drivers of aging

Hodes, R. J., Sierra, F., Austad, S. N., Epel, E., Neigh, G. N., Erlandson, K. M., Schafer, M. J., LeBrasseur, N. K., Wiley, C., Campisi, J., et al. (2016) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13299 · Cited by 132

A new method for CHD prediction and prevention based on regional risk scores and randomized clinical trials; PRECARD(R) and the Copenhagen Risk Score

Thomsen, T. F., Davidsen, M., Ibsen, H., Jorgensen, T., Jensen, G., & Borch-Johnsen, K. (2001) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1177/174182670100800508 · Cited by 127

Dietary sodium and risk of stroke in the Northern Manhattan Study

Gardener, H., Rundek, T., Wright, C. B., Elkind, M. S. V., & Sacco, R. L. (2012) · Stroke · doi:10.1161/strokeaha.111.641043 · Cited by 124

Chronic Management of Blood Pressure After Stroke

Pedelty, L., & Gorelick, P. B. (2004) · Hypertension · doi:10.1161/01.hyp.0000129170.50448.5f · Cited by 122

The Study on COgnition and Prognosis in the Elderly (SCOPE); outcomes in patients not receiving add-on therapy after randomization

Lithell, H., Hansson, L., Skoog, I., Elmfeldt, D., Hofman, A., Olofsson, B., Trenkwalder, P., & Zanchetti, A. (2004) · Journal of Hypertension · doi:10.1097/01.hjh.0000133730.47372.4c · Cited by 104

Epidemiological Perspective of Body Position and Arm Level in Blood Pressure Measurement

Terént, A., & Breig-åsberg, E. (1994) · Blood Pressure · doi:10.3109/08037059409102246 · Cited by 70

Orthostatic hypotension and anti-hypertensive therapy in the elderly

Fotherby, M. D., & Potter, J. F. (1994) · Postgraduate Medical Journal · doi:10.1136/pgmj.70.830.878 · Cited by 54

Second Australian National Blood Pressure Study (ANBP2). Australian Comparative Outcome Trial of ACE inhibitor- and diuretic-based treatment of hypertension in the elderly. Management Committee on Behalf of the High Blood Pressure Research Council of Australia

Wing, L. M. H., Reid, C. M., Ryan, P., Beilin, L. J., Brown, M. A., Jennings, G. L. R., Johnston, C. I., McNeil, J. J., Marley, J. E., Morgan, T. O., et al. (1997) · Clinical and Experimental Hypertension · doi:10.3109/10641969709083186 · Cited by 49

Progression of arterial stiffness is associated with midlife diastolic blood pressure and transition to late-life hypertensive phenotypes

Webb, A. J. S. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.119.014547 · Cited by 47

Identification of Risk Factors in Hypertensive Patients: Contribution of Randomized Controlled Trials Through an Individual Patient Database

Gueyffier, F., Boissel, J.-P., Pocock, S., Boutitie, F., Coope, J., Cutler, J., Ekbom, T., Fagard, R., Friedman, L., Kerlikowske, K., et al. (1999) · Circulation · doi:10.1161/01.cir.100.18.e88 · Cited by 46

Defining Thresholds for Home Blood Pressure Monitoring in Octogenarians

Aparicio, L. S., Thijs, L., Boggia, J., Jacobs, L., Barochiner, J., Odili, A. N., Alfie, J., Asayama, K., Cuffaro, P. E., Nomura, K., et al. (2015) · Hypertension · doi:10.1161/hypertensionaha.115.05800 · Cited by 45

Pharmacological treatment of hypertension in people without prior cerebrovascular disease for the prevention of cognitive impairment and dementia

Cunningham, E. L., Todd, S. A., Passmore, P., Bullock, R., & McGuinness, B. (2021) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004034.pub4 · Cited by 45

Doctors??? estimation of cardiovascular risk and willingness to give drug treatment in hypertension: fair risk assessment but defensive treatment policy

Persson, M., Carlberg, B., Tavelin, B., & Lindholm, L. H. (2004) · Journal of Hypertension · doi:10.1097/00004872-200401000-00014 · Cited by 37

Twenty-Four Hour Antihypertensive Efficacy of Indapamide, 1.5-Mg Sustained Release: Results of Two Randomized Double-Blind Controlled Studies

Mallion, J.-M., Asmar, R., Boutelant, S., & Guez, D. (1998) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-199810000-00023 · Cited by 32

Efficacy and safety of two treatment combinations of hypertension in very elderly patients

Fogari, R., Zoppi, A., Mugellini, A., Corradi, L., Lazzari, P., Preti, P., & Derosa, G. (2009) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2008.03.012 · Cited by 33

Cardiovascular disease in women: gender-specific aspects of hypertension and the consequences of treatment

LEGATO, M. J. (1998) · Journal of Women's Health · doi:10.1089/jwh.1998.7.199 · Cited by 22

Effects of gender and ethnic group on blood pressure control in the elderly

Svetkey, L. (1996) · American Journal of Hypertension · doi:10.1016/0895-7061(96)00026-x · Cited by 22

Review of nifedipine GITS in the treatment of high risk patients with coronary artery disease and hypertension

Lundy, A.-L. (2009) · Vascular Health and Risk Management · doi:10.2147/vhrm.s3066 · Cited by 19