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Ultrasonic Vocalizations as an Index of Positive Emotional State.
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“Research (see Bombail et al., 2021; LaFollette et al., 2017 for reviews) has shown that when rats are tickled by the human hand, they often produce 50 kHz USVs, which are understood to indicate positive affect in rats ( e.g., Barker, 2018, Figure 2i).”
From Stage 2 Registered Report: Refinement of tickling protocols to improve positive animal welfare in laboratory rats (2025) · cites this paper as Barker, 2018
In the citing paper
“We analysed 50 kHz USV as indicators of positive affective state ( e.g., Barker, 2018; Brudzynski, 2013).”
From Stage 2 Registered Report: Refinement of tickling protocols to improve positive animal welfare in laboratory rats (2025) · cites this paper as Barker, 2018
Citations
Cites
Drevets, W. C., Price, J. L., & Furey, M. L. (2008) · Brain Structure and Function · doi:10.1007/s00429-008-0189-x · Cited by 2,241
Encoding Predictive Reward Value in Human Amygdala and Orbitofrontal Cortex
Gottfried, J. A., O'Doherty, J., & Dolan, R. J. (2003) · Science · doi:10.1126/science.1087919 · Cited by 1,165
Orbitofrontal cortex, decision-making and drug addiction
Schoenbaum, G., Roesch, M. R., & Stalnaker, T. A. (2006) · Trends in Neurosciences · doi:10.1016/j.tins.2005.12.006 · Cited by 499
Burgdorf, J., Kroes, R. A., Moskal, J. R., Pfaus, J. G., Brudzynski, S. M., & Panksepp, J. (2008) · Journal of Comparative Psychology · doi:10.1037/a0012889 · Cited by 469
Reconstructing the evolution of laughter in great apes and humans
Davila Ross, M., J Owren, M., & Zimmermann, E. (2009) · Current Biology · doi:10.1016/j.cub.2009.05.028 · Cited by 286
Human neural learning depends on reward prediction errors in the blocking paradigm.
Tobler, P. N., O’Doherty, J. P., Dolan, R. J., & Schultz, W. (2006) · Journal of Neurophysiology · doi:10.1152/jn.00762.2005 · Cited by 209
Thompson, B., Leonard, K. C., & Brudzynski, S. M. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.10.012 · Cited by 182
Flagged first, then by citations
Research works printed but not linked: 49
- Achterberg, 2016, Dissociating the role of endocannabinoids in the pleasurable and motivational properties of social play behaviour in rats, Pharmacological Research, 110, 151, 10.1016/j.phrs.2016.04.031 · DOI
- Aharon, 2001, Beautiful faces have variable reward value: fMRI and behavioral evidence, Neuron, 32, 537, 10.1016/S0896-6273(01)00491-3 · DOI · Paper page
- Barfield, 1986, The role of ultrasonic vocalizations in the regulation of reproduction in rats, Annals of the New York Academy of Sciences, 474, 33, 10.1111/j.1749-6632.1986.tb27996.x · DOI
- Barker, 2014, Rat ultrasonic vocalizations demonstrate that the motivation to contextually reinstate cocaine-seeking behavior does not necessarily involve a hedonic response, Addiction Biology, 19, 781, 10.1111/adb.12044 · DOI
- Barker, 2014, Automated detection of 50-kHz ultrasonic vocalizations using template matching in XBAT, Journal of Neuroscience Methods, 236, 68, 10.1016/j.jneumeth.2014.08.007 · DOI
- Barker, 2010, Dose-dependent differences in short ultrasonic vocalizations emitted by rats during cocaine self-administration, Psychopharmacology, 211, 435, 10.1007/s00213-010-1913-9 · DOI
- Barker, 2014, Ultrasonic vocalizations: evidence for an affective opponent process during cocaine self-administration, Psychopharmacology, 231, 909, 10.1007/s00213-013-3309-0 · DOI
- Barker, 2015, Ultrasonic vocalizations as a measure of affect in preclinical models of drug abuse: a review of current findings, Current Neuropharmacology, 13, 193, 10.2174/1570159X13999150318113642 · DOI
- Bensafi, 2012, Dissociated representations of pleasant and unpleasant olfacto-trigeminal mixtures: an fMRI study, PLoS One, 7, 10.1371/journal.pone.0038358 · DOI
- Biały, 2000, Precontact 50-kHz vocalizations in male rats during acquisition of sexual experience, Behavioral Neuroscience, 114, 983, 10.1037/0735-7044.114.5.983 · DOI
- Blanchard, 1993, High-frequency (35-70 kHz) ultrasonic vocalizations in rats confronted with anesthetized conspecifics: effects of gepirone, ethanol, and diazepam, Pharmacology, Biochemistry, and Behavior, 44, 313, 10.1016/0091-3057(93)90467-8 · DOI
- Breiter, 2001, Functional imaging of neural responses to expectancy and experience of monetary gains and losses, Neuron, 30, 619, 10.1016/S0896-6273(01)00303-8 · DOI · Paper page
- Browning, 2011, Positive affective vocalizations during cocaine and sucrose self-administration: a model for spontaneous drug desire in rats, Neuropharmacology, 61, 268, 10.1016/j.neuropharm.2011.04.012 · DOI
- Brudzynski, 2014, The ascending mesolimbic cholinergic system—a specific division of the reticular activating system involved in the initiation of negative emotional states, Journal of Molecular Neuroscience, 53, 436, 10.1007/s12031-013-0179-1 · DOI
- Brudzynski, 1992, Ultrasonic vocalization of laboratory rats in response to handling and touch, Physiology and Behavior, 52, 655, 10.1016/0031-9384(92)90393-G · DOI
- Brudzynski, 2002, Social contacts and production of 50-kHz short ultrasonic calls in adult rats, Journal of Comparative Psychology, 116, 73, 10.1037/0735-7036.116.1.73 · DOI
- Buck, 2014, Dopamine D1 and μ-opioid receptor antagonism blocks anticipatory 50 kHz ultrasonic vocalizations induced by palatable food cues in Wistar rats, Psychopharmacology, 231, 929, 10.1007/s00213-013-3307-2 · DOI
- Burgdorf, 2017, Positive emotional learning induces resilience to depression: a role for NMDA receptor-mediated synaptic plasticity, Current Neuropharmacology, 15, 3, 10.2174/1570159X14666160422110344 · DOI
- Burgdorf, 2000, Anticipation of rewarding electrical brain stimulation evokes ultrasonic vocalization in rats, Behavioral Neuroscience, 114, 320, 10.1037/0735-7044.114.2.320 · DOI
- Burgdorf, 2007, Neurobiology of 50-kHz ultrasonic vocalizations in rats: electrode mapping, lesion, and pharmacology studies, Behavioural Brain Research, 182, 274, 10.1016/j.bbr.2007.03.010 · DOI
- Coffey, 2013, Effects of varying reinforcement probability on pavlovian approach behavior and ultrasonic vocalizations in rats, Behavioural Brain Research, 237, 256, 10.1016/j.bbr.2012.09.041 · DOI
- Davidson, 2002, Depression: perspectives from affective neuroscience, Annual Review of Psychology, 53, 545, 10.1146/annurev.psych.53.100901.135148 · DOI · Paper page
- Estes, 1941, Some quantitative properties of anxiety, Journal of Experimental Psychology, 29, 390, 10.1037/h0062283 · DOI
- Everitt, 1987, Studies of instrumental behavior with sexual reinforcement in male rats (Rattus norvegicus): I. Control by brief visual stimuli paired with a receptive female, Journal of Comparative Psychology, 101, 395, 10.1037/0735-7036.101.4.395 · DOI
- Galvan, 2005, The role of ventral frontostriatal circuitry in reward-based learning in humans, The Journal of Neuroscience, 25, 8650, 10.1523/JNEUROSCI.2431-05.2005 · DOI · Paper page
- Garavan, 2000, Cue-induced cocaine craving: neuroanatomical specificity for drug users and drug stimuli, American Journal of Psychiatry, 157, 1789, 10.1176/appi.ajp.157.11.1789 · DOI · Paper page
- Goldstein, 2002, Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex, American Journal of Psychiatry, 159, 1642, 10.1176/appi.ajp.159.10.1642 · DOI · Paper page
- Heath, 1963, Electrical self-stimulation of the brain in man, American Journal of Psychiatry, 120, 571, 10.1176/ajp.120.6.571 · DOI
- Johnson, 2011, Targeted training of ultrasonic vocalizations in aged and Parkinsonian rats, Journal of Visualized Experiments: JoVE, 54, e2835
- Keller, 2013, Trait anhedonia is associated with reduced reactivity and connectivity of mesolimbic and paralimbic reward pathways, Journal of Psychiatric Research, 47, 1319, 10.1016/j.jpsychires.2013.05.015 · DOI
- Knutson, 2001, Anticipation of increasing monetary reward selectively recruits nucleus accumbens, Journal of Neuroscience, 21, RC159, 10.1523/JNEUROSCI.21-16-j0002.2001 · DOI · Paper page
- Knutson, 1998, Anticipation of play elicits high-frequency ultrasonic vocalizations in young rats, Journal of Comparative Psychology, 112, 65, 10.1037/0735-7036.112.1.65 · DOI
- Knutson, 2002, Ultrasonic vocalizations as indices of affective states in rats, Psychological Bulletin, 128, 961, 10.1037/0033-2909.128.6.961 · DOI · Paper page
- McGinnis, 2003, Characterization of 50-kHz ultrasonic vocalizations in male and female rats, Physiology and Behavior, 80, 81, 10.1016/S0031-9384(03)00227-0 · DOI
- Moskal, 2011, A novel NMDA receptor glycine-site partial agonist, GLYX-13, has therapeutic potential for the treatment of autism, Neuroscience and Biobehavioral Reviews, 35, 1982, 10.1016/j.neubiorev.2011.06.006 · DOI
- O'Doherty, 2002, Neural responses during anticipation of a primary taste reward, Neuron, 33, 815, 10.1016/S0896-6273(02)00603-7 · DOI · Paper page
- Olds, 1954, Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain, Journal of Comparative and Physiological Psychology, 47, 419, 10.1037/h0058775 · DOI · Paper page
- Olds, 1963, Approach-avoidance analysis of rat diencephalon, Journal of Comparative Neurology, 120, 259, 10.1002/cne.901200206 · DOI
- Panksepp, 2000, 50-kHz chirping (laughter?) in response to conditioned and unconditioned tickle-induced reward in rats: effects of social housing and genetic variables, Behavioural Brain Research, 115, 25, 10.1016/S0166-4328(00)00238-2 · DOI · Paper page
- Sadananda, 2008, Playback of 22-kHz and 50-kHz ultrasonic vocalizations induces differential c-fos expression in rat brain, Neuroscience Letters, 435, 17, 10.1016/j.neulet.2008.02.002 · DOI
- Scardochio, 2015, The effects of electrical and optical stimulation of midbrain dopaminergic neurons on rat 50-kHz ultrasonic vocalizations, Frontiers in Behavioral Neuroscience, 9, 331, 10.3389/fnbeh.2015.00331 · DOI
- Schoenbaum, 1999, Neural encoding in orbitofrontal cortex and basolateral amygdala during olfactory discrimination learning, Journal of Neuroscience, 19, 1876, 10.1523/JNEUROSCI.19-05-01876.1999 · DOI · Paper page
- Simola, 2015, Rat ultrasonic vocalizations and behavioral neuropharmacology: from the screening of drugs to the study of disease, Current Neuropharmacology, 13, 164, 10.2174/1570159X13999150318113800 · DOI
- Thomas, 1985, Ultrasonic vocalization of the female rat (Rattus norvegicus) during mating, Animal Behaviour, 33, 720, 10.1016/S0003-3472(85)80002-6 · DOI
- Verleye, 2004, Effects of etifoxine on stress-induced hyperthermia, freezing behavior and colonic motor activation in rats, Physiology and Behavior, 82, 891, 10.1016/S0031-9384(04)00313-0 · DOI
- Wintink, 2001, The related roles of dopamine and glutamate in the initiation of 50-kHz ultrasonic calls in adult rats, Pharmacology Biochemistry and Behavior, 70, 317, 10.1016/S0091-3057(01)00615-3 · DOI
- Wise, 1996, Addictive drugs and brain stimulation reward, Annual Review of Neuroscience, 19, 319, 10.1146/annurev.ne.19.030196.001535 · DOI · Paper page
- Wittman, 2008, Mesolimbic interaction of emotional valence and reward improves memory formation, Neuropsychologia, 46, 1000, 10.1016/j.neuropsychologia.2007.11.020 · DOI
- Wöhr, 2007, Ultrasonic communication in rats: can playback of 50-kHz calls induce approach behavior?, PLoS One, 2, 10.1371/journal.pone.0001365 · DOI
Cited by
Sorted by citations
Bombail, V., Jerôme, N., Lam, H., Muszlak, S., Meddle, S. L., Lawrence, A. B., & Nielsen, B. L. (2019) · PLOS ONE · doi:10.1371/journal.pone.0212829 · Cited by 17
Bombail, V., Brown, S. M., Beyts, C., Martin, J. E., Li, T., Meddle, S. L., Mendl, M., Robinson, E. S., Hammond, T. J., Nielsen, B. L., et al. (2025) · F1000Research · doi:10.12688/f1000research.166417.2 · Cited by 4
“Research (see Bombail et al., 2021; LaFollette et al., 2017 for reviews) has shown that when rats are tickled by the human hand, they often produce 50 kHz USVs, which are understood to indicate positive affect in rats ( e.g. , Barker, 2018, Figure 2i).”
Metadata
- Authors
- Barker, D. J.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Barker, David J.
- Venue
- Handbook of Behavioral Neuroscience
- Publisher
- Elsevier
- Published
- 2018
- Pages
- 253-260
- ISSN
- 1569-7339 (ISSN-L)
- OpenAlex
- W2800599708
- Cited by
- 12
- References
- 7
- Citations by year
- 2025: 1 · 2024: 2 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 4
- FWCI
- 2.83
- Type
- book chapter
- Language
- en
- Open access
- closed
- Locations
- Handbook of behavioral neuroscience (publishedVersion)
- Rutgers University Community Repository (Rutgers University) (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Animal Vocal Communication and Behavior
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- ultrasonic vocalizations, 50-kHz vocalizations, positive emotions, reward processing, emotional behavior, psychopathology, mood disorders, anxiety disorders, drug addiction, eating disorders, autism spectrum disorder, rats
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