Nanostructured platinum grass enables superior impedance reduction for neural microelectrodes
Open accessAbstract
Micro-sized electrodes are essential for highly sensitive communication at the neural interface with superior spatial resolution. However, such small electrodes inevitably suffer from high electrical impedance and thus high levels of thermal noise deteriorating the signal to noise ratio. In order to overcome this problem, a nanostructured Pt-coating was introduced as add-on functionalization for impedance reduction of small electrodes. In comparison to platinum black deposition, all used chemicals in the deposition process are free from cytotoxic components. The grass-like nanostructure was found to reduce the impedance by almost two orders of magnitude compared to untreated samples which was lower than what could be achieved with conventional electrode coatings like IrOx or PEDOT. The realization of the Pt-grass coating is performed via a simple electrochemical process which can be applied to virtually any possible electrode type and accordingly shows potential as a universal impedance reduction strategy. Elution tests revealed non-toxicity of the Pt-grass and the coating was found to exhibit strong adhesion to the metallized substrate.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Deposition processes for platinum black have reportedly caused cytotoxic reactions due to lead traces found in the electroplating electrolyte, whereas this was not observed for nanostructured platinum grass.
“The deposition processes for platinum black have reportedly caused cytotoxic reactions due to lead traces found in the electroplating electrolyte (Schuettler et al. 2005b). This was not observed for nanostructured platinum grass (Boehler et al. 2015).”
From Realizing flexible bioelectronic medicines for accessing the peripheral nerves – technology considerations (2018) · cites this paper as Boehler et al. 2015
Cites
Mosmann, T. (1983) · Journal of Immunological Methods · doi:10.1016/0022-1759(83)90303-4 · Cited by 56,104 · see citing works
Restoring natural sensory feedback in real-time bidirectional hand prostheses
Raspopovic, S., Capogrosso, M., Petrini, F. M., Bonizzato, M., Rigosa, J., Di Pino, G., Carpaneto, J., Controzzi, M., Boretius, T., Fernandez, E., et al. (2014) · Science Translational Medicine · doi:10.1126/scitranslmed.3006820 · Cited by 1,001 · see citing works
Self-citationThe electrical properties of metal microelectrodes
Robinson, D. A. (1968) · Proceedings of the IEEE · doi:10.1109/proc.1968.6458 · Cited by 470 · see citing works
Rose, T. L., & Robblee, L. S. (1990) · IEEE Transactions on Biomedical Engineering · doi:10.1109/10.61038 · Cited by 359 · see citing works
Micromachined, Polyimide-Based Devices for Flexible Neural Interfaces
Stieglitz, T., Beutel, H., Schuettler, M., & Meyer, J.-U. (2000) · Biomedical Microdevices · doi:10.1023/a:1009955222114 · Cited by 343 · see citing works
Self-citationSun, S., Jaouen, F., & Dodelet, J. (2008) · Advanced Materials · doi:10.1002/adma.200800491 · Cited by 329 · see citing works
Organic electrode coatings for next-generation neural interfaces
Robles, U. A. A., Woolley, A. J., Poole-Warren, L. A., Lovell, N. H., & Green, R. A. (2014) · Frontiers in Neuroengineering · doi:10.3389/fneng.2014.00015 · Cited by 255 · see citing works
Substrate dependent stability of conducting polymer coatings on medical electrodes
Green, R. A., Hassarati, R. T., Bouchinet, L., Lee, C. S., Cheong, G. L. M., Yu, J., Dodds, C. W. D., Suaning, G. J., Poole-Warren, L. A., & Lovell, N. H. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.05.017 · Cited by 207 · see citing works
Blood pressure control with selective vagal nerve stimulation and minimal side effects
Plachta, D. T. T., Gierthmuehlen, M., Cota, O. F., Espinosa, N., Boeser, F., Herrera, T. C., Stieglitz, T., & Zentner, J. (2014) · Journal of Neural Engineering · doi:10.1088/1741-2560/11/3/036011 · Cited by 187 · see citing works
Self-citationGrowing Pt Nanowires as a Densely Packed Array on Metal Gauze
Lee, E. P., Peng, Z., Cate, D. M., Yang, H., Campbell, C. T., & Xia, Y. (2007) · Journal of the American Chemical Society · doi:10.1021/ja074312e · Cited by 184 · see citing works
Chapman, C. A. R., Chen, H., Stamou, M., Biener, J., Biener, M. M., Lein, P. J., & Şeker, E. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b00410 · Cited by 150 · see citing works
Sputtered iridium oxide films (SIROFs) for low-impedance neural stimulation and recording electrodes
Cogan, S. F., Plante, T. D., & Ehrlich, J. (2005) · The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society · doi:10.1109/iembs.2004.1404158 · Cited by 138 · see citing works
Desai, S. A. (2010) · Frontiers in Neuroengineering · doi:10.3389/fneng.2010.00005 · Cited by 124 · see citing works
Sensors and Decoding for Intracortical Brain Computer Interfaces
Homer, M. L., Nurmikko, A. V., Donoghue, J. P., & Hochberg, L. R. (2013) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-071910-124640 · Cited by 121 · see citing works
Thin films and microelectrode arrays for neuroprosthetics
Ordonez, J., Schuettler, M., Boehler, C., Boretius, T., & Stieglitz, T. (2012) · MRS Bulletin · doi:10.1557/mrs.2012.117 · Cited by 118 · see citing works
Self-citationElectrical Stimuli in the Central Nervous System Microenvironment
Thompson, D. M., Koppes, A. N., Hardy, J. G., & Schmidt, C. E. (2014) · Annual Review of Biomedical Engineering · doi:10.1146/annurev-bioeng-121813-120655 · Cited by 107 · see citing works
Preparation of strongly adherent platinum black coatings
Marrese, C. A. (1987) · Analytical Chemistry · doi:10.1021/ac00128a049 · Cited by 96 · see citing works
Stability of poly(3,4‐ethylene dioxythiophene) materials intended for implants
Thaning, E., Asplund, M., Nyberg, T., Inganäs, O., & von Holst, H. (2010) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.31597 · Cited by 92 · see citing works
Self-citationLaser patterning of platinum electrodes for safe neurostimulation
Green, R. A., Matteucci, P. B., Dodds, C. W. D., Palmer, J., Dueck, W. F., Hassarati, R. T., Byrnes-Preston, P., Lovell, N. H., & Suaning, G. J. (2014) · Journal of Neural Engineering · doi:10.1088/1741-2560/11/5/056017 · Cited by 77 · see citing works
Bionic vision: system architectures – a review
Guenther, T., Lovell, N. H., & Suaning, G. J. (2011) · Expert Review of Medical Devices · doi:10.1586/erd.11.58 · Cited by 76 · see citing works
Managing Chronic Pain With Spinal Cord Stimulation
Epstein, L. J., & Palmieri, M. (2012) · Mount Sinai Journal of Medicine A Journal of Translational and Personalized Medicine · doi:10.1002/msj.21289 · Cited by 68 · see citing works
Deep Brain Stimulation for Psychiatric Disorders
Holtzheimer, P., & Mayberg, H. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113638 · Cited by 65 · see citing works
Brain–computer interfaces: an overview of the hardware to record neural signals from the cortex
Stieglitz, T., Rubehn, B., Henle, C., Kisban, S., Herwik, S., Ruther, P., & Schüettler, M. (2009) · Progress in brain research · doi:10.1016/s0079-6123(09)17521-0 · Cited by 63 · see citing works
Self-citationOn the Stability of Poly‐Ethylenedioxythiopene as Coating Material for Active Neural Implants
Boretius, T., Schüettler, M., & Stieglitz, T. (2011) · Artificial Organs · doi:10.1111/j.1525-1594.2011.01210.x · Cited by 52 · see citing works
Self-citationBoehler, C., & Asplund, M. (2014) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.35252 · Cited by 47 · see citing works
Self-citationFabrication of strongly adherent platinum black coatings on microelectrodes array
Tang, R., Pei, W., Chen, S., Zhao, H., Chen, Y., Han, Y. F., Wang, C., & Chen, H. (2013) · Science China Information Sciences · doi:10.1007/s11432-013-4825-6 · Cited by 44 · see citing works
Human control model in teleoperation rendezvous
Zhang, B., Li, H., & Tang, G.-J. (2014) · Science China Information Sciences · doi:10.1007/s11432-013-5055-7 · Cited by 42 · see citing works
Schuettler, M. (2007) · Conference proceedings · doi:10.1109/iembs.2007.4352254 · Cited by 37 · see citing works
Dexter, S. J., Pearson, R. G., Davies, M. C., C�mara, M., & Shakesheff, K. M. (2001) · Journal of Biomedical Materials Research · doi:10.1002/1097-4636(200108)56:2 · Cited by 35 · see citing works
The influence of gold surface texture on microglia morphology and activation
Tan, Y. H., Terrill, S. E., Paranjape, G. S., Stine, K. J., & Nichols, M. R. (2013) · Biomaterials Science · doi:10.1039/c3bm60096c · Cited by 30 · see citing works
High-porous platinum electrodes for functional electrical stimulation
Boretius, T., Jurzinsky, T., Koehler, C., Kerzenmacher, S., Hillebrecht, H., & Stieglitz, T. (2011) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/iembs.2011.6091336 · Cited by 23 · see citing works
Self-citationCytotoxicity of platinum black
Schüettler, M., Doerge, T., Wien, S. L., Becker, S., Staiger, A., Hanauer, M., Kammer, S., & Stieglitz, T. (2005) · Publikationsdatenbank der Fraunhofer-Gesellschaft (Fraunhofer-Gesellschaft) · Cited by 18 · see citing works
Self-citationEffects of electrode size on the performance of neural recording microelectrodes
Hughes, M. P., Bustamante, K. D., Banks, D., & Ewins, D. J. (2002) · International IEEE-EMBS Special Topic Conference on Microtechnologies in Medicine and Biology (MMB) · doi:10.1109/mmb.2000.893776 · Cited by 14 · see citing works
Arrayed hybrid nanoporous Pt pillars
Park, S., Song, Y. J., Boo, H., Han, J., & Chung, T. D. (2009) · Electrochemistry Communications · doi:10.1016/j.elecom.2009.09.036 · Cited by 11 · see citing works
Flagged first, then by citations
1 of the 35 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Piech, D. K., Johnson, B. C., Shen, K., Ghanbari, M. M., Li, K. Y., Neely, R. M., Kay, J. E., Carmena, J. M., Maharbiz, M. M., & Muller, R. (2020) · Nature Biomedical Engineering · doi:10.1038/s41551-020-0518-9 · Cited by 442 · see citing works
Two-Dimensional Ti 3 C 2 MXene for High-Resolution Neural Interfaces
Driscoll, N., Richardson, A. G., Maleski, K., Anasori, B., Adewole, D. O., Lelyukh, P., Escobedo, L., Cullen, D. K., Lucas, T. H., Gogotsi, Y. G., et al. (2018) · ACS Nano · doi:10.1021/acsnano.8b06014 · Cited by 317 · see citing works
Boehler, C., Carli, S., Fadiga, L., Stieglitz, T., & Asplund, M. (2020) · Nature Protocols · doi:10.1038/s41596-020-0389-2 · Cited by 311 · see citing works
Self-citationMachine Learning‐Driven Biomaterials Evolution
Suwardi, A., Wang, F., Xue, K., Han, M., Teo, P., Wang, P., Wang, S., Liu, Y., Ye, E., Zibiao, L., et al. (2021) · Advanced Materials · doi:10.1002/adma.202102703 · Cited by 307 · see citing works
Emerging Modalities and Implantable Technologies for Neuromodulation
Won, S. M., Song, E., Reeder, J. T., & Rogers, J. A. (2020) · Cell · doi:10.1016/j.cell.2020.02.054 · Cited by 293 · see citing works
Graphene in the design and engineering of next‐generation neural interfaces
Kostarelos, K., Vincent, M., Hebert, C., & Garrido, J. A. (2017) · Advanced Materials · doi:10.1002/adma.201700909 · Cited by 206 · see citing works
Boehler, C., Oberueber, F., Schlabach, S., Stieglitz, T., & Asplund, M. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b13468 · Cited by 203 · see citing works
Self-citationHigh‐Performance Graphene‐Fiber‐Based Neural Recording Microelectrodes
Wang, K., Frewin, C. L., Esrafilzadeh, D., Yu, C., Wang, C., Pancrazio, J. J., Romero‐Ortega, M. I., Jalili, R., & Wallace, G. G. (2019) · Advanced Materials · doi:10.1002/adma.201805867 · Cited by 193 · see citing works
Gulino, M., Kim, D., Pané, S., Santos, S. D., & Pêgo, A. P. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00689 · Cited by 159 · see citing works
Wen, X., Wang, B., Huang, S., Liu, T. “., Lee, M., Chung, P., Chow, Y. T., Huang, I.-W., Monbouquette, H. G., Maidment, N. T., et al. (2019) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2019.01.060 · Cited by 162 · see citing works
A wearable freestanding electrochemical sensing system
Zhao, Y., Wang, B., Hojaiji, H., Wang, Z., Lin, S., Yeung, C. J., Lin, H., Nguyen, P., Chiu, K., Salahi, K., et al. (2020) · Science Advances · doi:10.1126/sciadv.aaz0007 · Cited by 142 · see citing works
Implantable intracortical microelectrodes: reviewing the present with a focus on the future
Wang, Y., Yang, X., Zhang, X., Wang, Y., & Pei, W. (2023) · Microsystems & Nanoengineering · doi:10.1038/s41378-022-00451-6 · Cited by 145 · see citing works
Optimal Electrode Size for Multi-Scale Extracellular-Potential Recording From Neuronal Assemblies
Viswam, V., Obien, M. E. J., Franke, F., Frey, U., & Hierlemann, A. R. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00385 · Cited by 136 · see citing works
Gold nanostructures: synthesis, properties, and neurological applications
Zare, I., Yaraki, M. T., Speranza, G., Najafabadi, A. H., Shourangiz-Haghighi, A., Nik, A. B., Manshian, B. B., Saraiva, C., Soenen, S. J., Kogan, M. J., et al. (2022) · Chemical Society Reviews · doi:10.1039/d1cs01111a · Cited by 132 · see citing works
Zeng, Q., & Huang, Z. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202301223 · Cited by 103 · see citing works
Conducting polymers for neuronal microelectrode array recording and stimulation
Aqrawe, Z., Montgomery, J. M., Travaš‐Sejdić, J., & Svirskis, D. M. (2017) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2017.11.023 · Cited by 92 · see citing works
Bianchi, M., Salvo, A. D., Asplund, M., Carli, S., Lauro, M. D., Schulze‐Bonhage, A., Stieglitz, T., Fadiga, L., & Biscarini, F. (2022) · Advanced Science · doi:10.1002/advs.202104701 · Cited by 89 · see citing works
Self-citationNanoPtA Nanostructured Electrode Coating for Neural Recording and Microstimulation
Boehler, C., Vieira, D. M., Egert, U., & Asplund, M. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b22798 · Cited by 88 · see citing works
Self-citationFiáth, R., Raducanu, B. C., Musa, S., Andrei, A., López, C. M., Hoof, C. A. V., Ruther, P., Aarts, A. A. A., Horváth, D., & Ulbert, I. (2018) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2018.01.060 · Cited by 81 · see citing works
Electrodeposited PEDOT:Nafion Composite for Neural Recording and Stimulation
Carli, S., Bianchi, M., Zucchini, E., Lauro, M. D., Prato, M., Murgia, M., Fadiga, L., & Biscarini, F. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201900765 · Cited by 80 · see citing works
Micro- and nanotechnology for neural electrode-tissue interfaces
Liu, S., Zhao, Y., Hao, W., Zhang, X., & Ming, D. (2020) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2020.112645 · Cited by 79 · see citing works
Scalable batch fabrication of ultrathin flexible neural probes using a bioresorbable silk layer
Cointe, C., Laborde, A., Nowak, L. G., Arvanitis, D. N., Bourrier, D., Bergaud, C., & Maziz, A. (2022) · Microsystems & Nanoengineering · doi:10.1038/s41378-022-00353-7 · Cited by 78 · see citing works
Neural interfaces engineered via micro- and nanostructured coatings
Chen, N., Tian, L., Patil, A. C., Peng, S., Yang, I. H., Thakor, N. V., & Ramakrishna, S. (2017) · Nano Today · doi:10.1016/j.nantod.2017.04.007 · Cited by 74 · see citing works
Boehler, C., Oberueber, F., & Asplund, M. (2019) · Journal of Controlled Release · doi:10.1016/j.jconrel.2019.05.017 · Cited by 68 · see citing works
Self-citationInterfacing with the Brain: How Nanotechnology Can Contribute
Ahmed, A. A. A., Alegret, N., Almeida, B., Álvarez‐Puebla, R. A., Andrews, A. M., Ballerini, L., Barrios‐Capuchino, J. J., Becker, C., Blick, R. H., Bonakdar, S., et al. (2025) · ACS Nano · doi:10.1021/acsnano.4c10525 · Cited by 68 · see citing works
Zeng, Q., Xia, K., Sun, B., Yin, Y., Wu, T., & Humayun, M. S. (2017) · Electrochimica Acta · doi:10.1016/j.electacta.2017.03.213 · Cited by 65 · see citing works
Giagka, V., & Serdijn, W. A. (2018) · Bioelectronic Medicine · doi:10.1186/s42234-018-0010-y · Cited by 58 · see citing works
Park, Y., Chung, T. S., Lee, G., & Rogers, J. A. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00639 · Cited by 60 · see citing works
Recording Quality Is Systematically Related to Electrode Impedance
Lewis, C. M., Boehler, C., Liljemalm, R., Fries, P., Stieglitz, T., & Asplund, M. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202303401 · Cited by 58 · see citing works
Self-citationAlcaide, M. J., Taylor, A., Fjorback, M. V., Zachar, V., & Pennisi, C. P. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00087 · Cited by 53 · see citing works
Electrochemical Evaluations of Fractal Microelectrodes for Energy Efficient Neurostimulation
Park, H., Takmakov, P. A., & Lee, H. (2018) · Scientific Reports · doi:10.1038/s41598-018-22545-w · Cited by 53 · see citing works
Engineering strategies towards overcoming bleeding and glial scar formation around neural probes
Otte, E., Vlachos, A., & Asplund, M. (2022) · Cell and Tissue Research · doi:10.1007/s00441-021-03567-9 · Cited by 50 · see citing works
Self-citationAqrawe, Z., Wright, B. E., Patel, N. D., Vyas, Y., Malmström, J., Montgomery, J. M., Williams, D. E., Travaš‐Sejdić, J., & Svirskis, D. M. (2018) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2018.10.099 · Cited by 49 · see citing works
Yin, P., Liu, Y., Xiao, L., & Zhang, C. (2021) · Polymers · doi:10.3390/polym13162834 · Cited by 42 · see citing works
An autonomous wearable system for diurnal sweat biomarker data acquisition
Hojaiji, H., Zhao, Y., Gong, M. C., Mallajosyula, M., Tan, J., Lin, H., Hojaiji, A. M., Lin, S., Milla, C. E., Madni, A. M., et al. (2020) · Lab on a Chip · doi:10.1039/d0lc00820f · Cited by 41 · see citing works
Chen, Z., Boyajian, N., Lin, Z., Yin, R. T., Obaid, S. N., Tian, J., Brennan, J. A., Chen, S. W., Miniovich, A. N., Lin, L., et al. (2021) · Advanced Materials Technologies · doi:10.1002/admt.202100225 · Cited by 38 · see citing works
Electrical Stimulation of Cells: Drivers, Technology, and Effects
Kadan-Jamal, K., Wronowski, F., Jin, A. T., Naegele, T. E., Montes, V. R., Tao, X., Dominguez‐Alfaro, A., Lee, C., & Malliaras, G. G. (2025) · Chemical Reviews · doi:10.1021/acs.chemrev.4c00468 · Cited by 38 · see citing works
Vallejo‐Giraldo, C., Krukiewicz, K., Calaresu, I., Zhu, J., Palma, M., Fernández, M., McDowell, B. W., Peixoto, N., Farid, N., O’Connor, G. M., et al. (2018) · Small · doi:10.1002/smll.201800863 · Cited by 39 · see citing works
Zeng, Q., Yu, S., Fan, Z., Huang, Y., Song, B., & Zhou, T. (2022) · Nanomaterials · doi:10.3390/nano12193445 · Cited by 37 · see citing works
Biomimetic Nanostructures Fabricated by Nanoimprint Lithography for Improved Cell‐Coupling
Nowduri, B., Schulte, S., Decker, D., Schäfer, K., & Saumer, M. (2020) · Advanced Functional Materials · doi:10.1002/adfm.202004227 · Cited by 36 · see citing works
Multifunctional Neural Interfaces for Closed‐Loop Control of Neural Activity
Chapman, C. A. R., Goshi, N., & Şeker, E. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201703523 · Cited by 35 · see citing works
Electroresponsive Hydrogels for Therapeutic Applications in the Brain
Khan, Z. M., Wilts, E. M., Vlaisavljevich, E., Long, T. E., & Verbridge, S. S. (2021) · Macromolecular Bioscience · doi:10.1002/mabi.202100355 · Cited by 36 · see citing works
Gao, W., Yan, Z., Zhou, H., Xie, Y., Wang, H., Yang, J., Yu, J., Ni, C., Liu, P., Xie, M., et al. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03573-x · Cited by 38 · see citing works
Harland, B. C., Aqrawe, Z., Vomero, M., Boehler, C., Cheah, E., Raos, B. J., Asplund, M., O’Carroll, S. J., & Svirskis, D. M. (2022) · Advanced Science · doi:10.1002/advs.202105913 · Cited by 30 · see citing works
Self-citationMicro/Nano Technologies for High-Density Retinal Implant
Zeng, Q., Zhao, S., Yang, H., Zhang, Y., & Wu, T. (2019) · Micromachines · doi:10.3390/mi10060419 · Cited by 31 · see citing works
Wang, B., Wen, X., Cao, Y. F., Huang, S., Lam, H. A., Liu, T. “., Chung, P., Monbouquette, H. G., Chiou, P.-Y. E., & Maidment, N. T. (2020) · Lab on a Chip · doi:10.1039/d0lc00021c · Cited by 29 · see citing works
Wang, B., Wen, X., Chiou, P.-Y. E., & Maidment, N. T. (2019) · Electroanalysis · doi:10.1002/elan.201900362 · Cited by 28 · see citing works
Shokoohimehr, P., Čepkenović, B., Miloš, F., Bednár, J., Hassani, H., Maybeck, V., & Offenhäusser, A. (2022) · Small · doi:10.1002/smll.202200053 · Cited by 27 · see citing works
Amini, S., Seche, W., May, N., Choi, H., Tavousi, P., & Shahbazmohamadi, S. (2022) · Scientific Reports · doi:10.1038/s41598-022-18161-4 · Cited by 27 · see citing works
Zeng, Q., Xia, K., Zhang, Y., & Wu, T. (2019) · Advanced Materials Interfaces · doi:10.1002/admi.201900356 · Cited by 27 · see citing works
Lee, J., Gänswein, T., Uluşan, H., Emmenegger, V., Saguner, A. M., Duru, F., & Hierlemann, A. R. (2022) · ACS Sensors · doi:10.1021/acssensors.2c01678 · Cited by 25 · see citing works
Rapid prototyping of flexible intrafascicular electrode arrays by picosecond laser structuring
Mueller, M. C., de la Oliva, N., del Valle, J., Delgado-Martínez, I., Navarro, X., & Stieglitz, T. (2017) · Journal of Neural Engineering · doi:10.1088/1741-2552/aa7eea · Cited by 24 · see citing works
Self-citationEffects of nanostructuration on the electrochemical performance of metallic bioelectrodes
Mobini, S., González, M. U., Caballero‐Calero, O., Patrick, E. E., Martín‐González, M., & García‐Martín, J. M. (2022) · Nanoscale · doi:10.1039/d1nr06280h · Cited by 24 · see citing works
Fiáth, R., Hofer, K. T., Csikós, V., Horváth, D., Nánási, T., Tóth, K., Pothof, F., Böhler, C., Asplund, M., Ruther, P., et al. (2018) · Biomedizinische Technik/Biomedical Engineering · doi:10.1515/bmt-2017-0154 · Cited by 24 · see citing works
Self-citationIn vitro and in vivo stability of black-platinum coatings on flexible, polymer microECoG arrays
Zátonyi, A., Fedor, F. Z., Borhegyi, Z., & Fekete, Z. (2018) · Journal of Neural Engineering · doi:10.1088/1741-2552/aacf71 · Cited by 25 · see citing works
Fabrication of Ti3C2 MXene Microelectrode Arrays for In Vivo Neural Recording
Driscoll, N., Maleski, K., Richardson, A. G., Murphy, B. B., Anasori, B., Lucas, T. H., Gogotsi, Y. G., & Vitale, F. (2020) · Journal of Visualized Experiments · doi:10.3791/60741 · Cited by 24 · see citing works
Zhao, Q., Zhu, M. J., Tian, G., Liang, C., Liu, Z., Huang, J., Yu, Q. Y., Tang, S., Chen, J., Zhao, X., et al. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202203344 · Cited by 23 · see citing works
Deciphering platinum dissolution in neural stimulation electrodes: Electrochemistry or biology?
Shah, D., Carter, P., Shivdasani, M. N., Fong, N., Duan, W., Esrafilzadeh, D., Poole-Warren, L. A., & Robles, U. A. A. (2024) · Biomaterials · doi:10.1016/j.biomaterials.2024.122575 · Cited by 26 · see citing works
Lee, Y. J., Kim, H., Kang, J. Y., Hee, S., & Lee, S. H. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201601022 · Cited by 23 · see citing works
Self-supporting carbon nanotube films as flexible neural interfaces
Krukiewicz, K., Janas, D. W., Vallejo‐Giraldo, C., & Biggs, M. J. P. (2018) · Electrochimica Acta · doi:10.1016/j.electacta.2018.10.157 · Cited by 23 · see citing works
Think big, see small—A review of nanomaterials for neural interfaces
Zeng, Q., Li, X., Zhang, S., Deng, C., & Wu, T. (2021) · Nano Select · doi:10.1002/nano.202100256 · Cited by 22 · see citing works
Qian, S., Lin, H., Pan, Q., Zhang, S., Zhang, Y., Geng, Z. H., Wu, Q. Y., He, Y. W., & Zhu, B. (2023) · Bioactive Materials · doi:10.1016/j.bioactmat.2023.02.010 · Cited by 22 · see citing works
Advanced Electrical and Optical Microsystems for Biointerfacing
Obaid, S. N., Chen, Z., & Lu, L. (2020) · Advanced Intelligent Systems · doi:10.1002/aisy.202000091 · Cited by 21 · see citing works
Functional Two-Dimensional Materials for Bioelectronic Neural Interfacing
Akbari, M. K., Lopa, N. S., Shahriari, M., Najafzadehkhoee, A., Galusek, D., & Zhuiykov, S. (2023) · Journal of Functional Biomaterials · doi:10.3390/jfb14010035 · Cited by 20 · see citing works
Highly Porous Platinum Electrodes for Dry Ear-EEG Measurements
Eickenscheidt, M., Schäfer, P., Baslan, Y., Schwarz, C., & Stieglitz, T. (2020) · Sensors · doi:10.3390/s20113176 · Cited by 20 · see citing works
Self-citationSim, S., Shin, H., Bae, K., Han, H., Kang, Y., Woo, J., Cho, Y., Cho, I., & Kim, J. (2023) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2023.134124 · Cited by 19 · see citing works
An Implantable Biohybrid Neural Interface Toward Synaptic Deep Brain Stimulation
Sifringer, L., Fratzl, A., Clément, B., Chansoria, P., Mönkemöller, L. S., Duru, J., Ihle, S. J., Steffens, S., Beltraminelli, A., Ceylan, E., et al. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202416557 · Cited by 23 · see citing works
Kelly, A., Farid, N., Krukiewicz, K., Belisle, N., Groarke, J. D., Waters, E. M., Trotier, A., Laffir, F. R., Kilcoyne, M., O’Connor, G. M., et al. (2020) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.9b01321 · Cited by 18 · see citing works
System for recording from multiple flexible polyimide neural probes in freely behaving animals
van Daal, R. J. J., Sun, J.-J., Ceyssens, F., Michon, F., Kraft, M., Puers, R., & Kloosterman, F. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/ab5e19 · Cited by 18 · see citing works
Lichtenstein, M. P., Pérez, E., Ballesteros, L. A., Sunol, C. E., & Casañ-Pastor, N. (2017) · Applied Materials Today · doi:10.1016/j.apmt.2016.12.002 · Cited by 18 · see citing works
Ramesh, V., Stratmann, N., Schaufler, V., Angelov, S. D., Nordhorn, I. D., Heissler, H. E., Martínez‐Hincapié, R., Čolić, V., Rehbock, C., Schwabe, K., et al. (2022) · Advanced Healthcare Materials · doi:10.1002/adhm.202102637 · Cited by 18 · see citing works
Kleber, C., Lienkamp, K., Rühe, J., & Asplund, M. (2019) · Advanced Biosystems · doi:10.1002/adbi.201900072 · Cited by 18 · see citing works
Self-citationArray-wide uniform PEDOT:PSS electroplating from potentiostatic deposition
Shin, Y., Ryu, J., Bai, T., Qiang, Y., Qi, Y., Li, G., Huang, Y., Seo, K. J., & Fang, H. (2024) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2024.116418 · Cited by 17 · see citing works
Torres-Martinez, N., Crétallaz, C., Ratel, D., Mailley, P., Gaude, C., Costecalde, T., Hébert, C., Bergonzo, P., Scorsone, E., Mazellier, J.-P., et al. (2019) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2019.05.007 · Cited by 16 · see citing works
Maiolo, L., Polese, D., & Convertino, A. (2019) · Advances in Physics X · doi:10.1080/23746149.2019.1664319 · Cited by 18 · see citing works
Vandekerckhove, B., Missinne, J., Vonck, K. E. J., Bauwens, P., Verplancke, R., Boon, P., Raedt, R., & Vanfleteren, J. (2020) · Micromachines · doi:10.3390/mi12010038 · Cited by 15 · see citing works
Koenen, S., Rehbock, C., Heissler, H. E., Angelov, S. D., Schwabe, K., Krauss, J. K., & Barcikowski, S. (2017) · ChemPhysChem · doi:10.1002/cphc.201601180 · Cited by 15 · see citing works
3D conductive material strategies for modulating and monitoring cells
Li, X., Mao, M., Han, K., Yao, C., Gu, B., He, J., & Li, D. (2022) · Progress in Materials Science · doi:10.1016/j.pmatsci.2022.101041 · Cited by 14 · see citing works
Li, L., Jiang, C., & Li, L. (2023) · Micromachines · doi:10.3390/mi15010070 · Cited by 13 · see citing works
Aqrawe, Z., Patel, N. D., Vyas, Y., Bansal, M., Montgomery, J. M., Travaš‐Sejdić, J., & Svirskis, D. M. (2020) · PLoS ONE · doi:10.1371/journal.pone.0237709 · Cited by 13 · see citing works
Nanostructured platinum as an electrochemically and mechanically stable electrode coating
Boehler, C., Oberueber, F., Stieglitz, T., & Asplund, M. (2017) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2017.8037009 · Cited by 13 · see citing works
Self-citationRamesh, V., Rehbock, C., Giera, B., Karnes, J. J., Forien, J., Angelov, S. D., Schwabe, K., Krauss, J. K., & Barcikowski, S. (2021) · Langmuir · doi:10.1021/acs.langmuir.1c01081 · Cited by 13 · see citing works
Cortelli, G., Grob, L., Patruno, L., Cramer, T., Mayer, D., Fraboni, B., Wolfrum, B. L., & de Miranda, S. (2023) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.2c21921 · Cited by 12 · see citing works
It's the little things: On the complexity of planar electrode heating in MRI
Erhardt, J. B., Lottner, T., Martinez, J., Özen, A. Ç., Schüettler, M., Stieglitz, T., Ennis, D. B., & Bock, M. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.03.061 · Cited by 12 · see citing works
Self-citationYang, X., Pei, W., Wei, C., Yang, X., Zhang, H., Wang, Y., Yuan, M., Gui, Q., Liu, Y., Wang, Y., et al. (2022) · Sensors and Actuators A Physical · doi:10.1016/j.sna.2022.114022 · Cited by 11 · see citing works
Khosla, H., Seche, W., Ammerman, D., Elyahoodayan, S., Caputo, G. A., Hettinger, J. D., Amini, S., & Feng, G. (2023) · Scientific Reports · doi:10.1038/s41598-023-47256-9 · Cited by 11 · see citing works
Porous PU/PEDOT:PSS electrodes for probing bioelectricity in Oscillatoria sp. Cohorts
Cotta, F. C., Correia, D., Amaral, R., Bacellar, F. L., Duci, D., Lopes, L., Cortes, L., Zalar, P., Perkins, R. G., & Rocha, P. R. F. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.155480 · Cited by 11 · see citing works
Neural Electrode Based on 3D Microscale/Nanoscale Porous Graphene Structures for Neural Stimulation
Movaghgharnezhad, S., Kim, H., Khan, M. A., Ross, S. E., Kim, B. G., & Kang, P. (2024) · ACS Applied Nano Materials · doi:10.1021/acsanm.4c03772 · Cited by 11 · see citing works
Highly Flexible Precisely Braided Multielectrode Probes and Combinatorics for Future Neuroprostheses
Kim, T., Schmidt, K., Deemie, C., Wycech, J., Liang, H., & Giszter, S. F. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00613 · Cited by 10 · see citing works
Fabrication of vertically aligned PEDOT nanotube arrays on microelectrodes to interface neurons
Chen, H., Tian, G., Yan, H., Yang, S., & Kim, D. (2021) · Electrochimica Acta · doi:10.1016/j.electacta.2021.139583 · Cited by 11 · see citing works
Ramesh, V., Giera, B., Karnes, J. J., Stratmann, N., Schaufler, V., Li, Y., Rehbock, C., & Barcikowski, S. (2022) · Journal of The Electrochemical Society · doi:10.1149/1945-7111/ac51f8 · Cited by 11 · see citing works
Page, N., Lucchi, J., Buchan, J., Fones, A., Hamilton, H., Scabarozi, T. H., Yu, L., Amini, S., & Hettinger, J. D. (2021) · Materials Today Communications · doi:10.1016/j.mtcomm.2021.102967 · Cited by 11 · see citing works
Krukiewicz, K., Fernández, J., Skorupa, M., Więcławska, D., Poudel, A., Sarasua, J.-R., Quinlan, L. R., & Biggs, M. J. P. (2019) · BMC Biomedical Engineering · doi:10.1186/s42490-019-0010-3 · Cited by 11 · see citing works
Acquisition of bioelectrical signals with small electrodes
Viswam, V., Obien, M. E. J., Frey, U., Franke, F., & Hierlemann, A. R. (2017) · IEEE Biomedical Circuits and Systems Conference (BioCAS) · doi:10.1109/biocas.2017.8325216 · Cited by 10 · see citing works
Slippery Epidural ECoG Electrode for High-Performance Neural Recording and Interface
Alahi, M. E. E., Liu, Y., Khademi, S., Nag, A., Wang, H., Wu, T., & Mukhopadhyay, S. C. (2022) · Biosensors · doi:10.3390/bios12111044 · Cited by 10 · see citing works
Toward the Next Generation of Neural Iontronic Interfaces
Forró, C., Musall, S., Montes, V. R., Linkhorst, J., Walter, P., Weßling, M., Offenhäusser, A., Ingebrandt, S., Weber, Y. G., Lampert, A., et al. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202301055 · Cited by 8 · see citing works
Vajrala, V. S., Elkhoury, K., Pautot, S., Bergaud, C., & Maziz, A. (2022) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2023.115182 · Cited by 9 · see citing works
Improving Fast Ripples Recording With Model-Guided Design of Microelectrodes
Harrach, M. A., Dauly, G., Mousavi, H., Dieuset, G., Benquet, P., Ismailova, E., & Wendling, F. (2023) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2023.3250763 · Cited by 9 · see citing works
Evaluation of Polymer-Coated Carbon Nanotube Flexible Microelectrodes for Biomedical Applications
Ruhunage, C. K., Dhawan, V., Nawarathne, C. P., Hoque, A., Cui, X. T., & Alvarez, N. T. (2023) · Bioengineering · doi:10.3390/bioengineering10060647 · Cited by 9 · see citing works
Jiao, Y., Miao, L., Zhu, J., Chang, R., & Qu, X. (2023) · PubMed Central · doi:10.12336/biomatertransl.2023.04.003 · Cited by 9 · see citing works
- Authors
- Boehler, C., Stieglitz, T., & Asplund, M.
- Affiliations
- University of Freiburg (DE)
- Corresponding author
- Boehler, C.
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2015-10
- Volume
- 67
- Pages
- 346-353
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W1190686642
- Cited by
- 179
- References
- 35
- Citations by year
- 2026: 16 · 2025: 19 · 2024: 19 · 2023: 21 · 2022: 21 · 2021: 17 · 2020: 19 · 2019: 22 · 2018: 10 · 2017: 11 · 2016: 4
- FWCI
- 3.87
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Biomaterials (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- FreiDok plus (Universitätsbibliothek Freiburg) (submittedVersion)
- Funders
- German Research Foundation (EXC 1086)
- Freiburg Institute for Advanced Studies (FRIAS), funded by the German Excellence Initiative
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
- Physical Sciences › Chemistry › Electrochemistry › Electrochemical Analysis and Applications
- Keywords
- neural microelectrodes, platinum coating, platinum black, electrodeposition, neural interfaces, thermal noise, signal-to-noise ratio, electrode functionalization, cytotoxicity, coating adhesion
- MeSH terms
- Cell Survival, Humans, Imides, Microelectrodes, Neurons, Platinum, Electric Impedance, Cell Line, Tumor, Nanostructures, Electrochemical Techniques, Optical Imaging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
