Cited by 167Obsessive-Compulsive Spectrum DisordersNeural and Behavioral Psychology StudiesDeep Brain Stimulation and Movement Disorders

The DOI matches its Crossref record; 58 of the 58 references it cites were found in a registry or an index.

Functional magnetic resonance imaging study of regional brain activation during implicit sequence learning in obsessive-compulsive disorder

Rauch, Scott L., Wedig, Michelle M., Wright, Christopher I., Martis, Brian, McMullin, Katherine G., Shin, Lisa M., Cannistraro, Paul A., Wilhelm, Sabine·2007·Biological Psychiatry

DOI 10.1016/j.biopsych.2005.12.012

Open this paper in CoChat — free account

Abstract

Background Corticostriatal circuitry has been implicated in the pathophysiology of obsessive-compulsive disorder (OCD). The serial reaction time (SRT) task, a paradigm that tests implicit sequence learning, has been used with imaging to probe striatal function. Initial studies have indicated that OCD patients exhibit deficient striatal activation and aberrant hippocampal recruitment compared with healthy control (HC) subjects. Here, we used the SRT and functional magnetic resonance imaging (fMRI) to replicate prior results in a larger sample and to test for relationships between regional activation and OCD symptom dimensions.Methods Using SPM99, fMRI-SRT data from 12 OCD and 12 matched HC subjects were analyzed. Symptom dimensions followed a four-factor model scored on a 0- to 10-point scale.Results For the implicit learning versus random contrast, group by condition interactions revealed aberrant recruitment within the hippocampus as well as orbitofrontal cortex (OCD > HC) but no striatal group differences. However, an inverse correlation was found between striatal activation and specific symptom factors.Conclusions These results replicate previous smaller studies showing aberrant hippocampal recruitment in OCD during SRT performance. Although findings of deficient striatal activation in OCD were not replicated, correlation results suggest that this inconsistency may be attributable to differences among OCD symptom dimensions.

Integrity signals

Registry

Crossref · 10.1016/j.biopsych.2005.12.012

Cites

58 of 58 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

An inventory for measuring depression
BECK, A. T. (1961) · Archives of General Psychiatry · doi:10.1001/archpsyc.1961.01710120031004 · Cited by 38,032
The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900
The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability
Goodman, W. K. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810110048007 · Cited by 7,712
J Neuropsychiatry Clin Neurosci
Yudofsky, S. C., & Hales, R. E. (1992) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.4.4.359 · Cited by 3,818
Attentional requirements of learning: Evidence from performance measures
Nissen, M. J., & Bullemer, P. (1987) · Cognitive Psychology · doi:10.1016/0010-0285(87)90002-8 · Cited by 2,966
The Yale-Brown Obsessive Compulsive Scale: II. Validity
Goodman, W. K. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810110054008 · Cited by 2,799
The Yale-Brown Obsessive-Compulsive Scale: measures of internal consistency.
Kim, S.-W., Dysken, M., Pheley, A., & Hoover, K. M. (1994) · Psychiatry Research · doi:10.1016/0165-1781(94)90039-6 · Cited by 2,333
Response and Habituation of the Human Amygdala during Visual Processing of Facial Expression
Breiter, H. C., Etcoff, N. L., Whalen, P. J., Kennedy, W. A., Rauch, S. L., Buckner, R. L., Strauss, M. M., Hyman, S. E., & Rosen, B. R. (1996) · Neuron · doi:10.1016/s0896-6273(00)80219-6 · Cited by 1,711
Self-citation
Comparing Functional (PET) Images: The Assessment of Significant Change
Friston, K. J., Frith, C., Liddle, P. F., & Frackowiak, R. S. J. (1991) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1991.122 · Cited by 1,626
Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive-compulsive disorder
Baxter, L. R. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820090009002 · Cited by 1,293

Show all 57 references

Sorted by citations

Habits, Rituals, and the Evaluative Brain
Graybiel, A. M. (2008) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.29.051605.112851 · Cited by 1,697
Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: The orbitofronto-striatal model revisited
Menzies, L., Chamberlain, S. R., Laird, A. R., Thelen, S. M., Sahakian, B. J., & Bullmore, E. T. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.09.005 · Cited by 1,190
A Heuristic for Developing Transdiagnostic Models of Psychopathology: Explaining Multifinality and Divergent Trajectories
Nolen-Hoeksema, S., & Watkins, E. R. (2011) · Perspectives on Psychological Science · doi:10.1177/1745691611419672 · Cited by 863
Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways
Milad, M. R., & Rauch, S. L. (2012) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2011.11.003 · Cited by 847
Self-citation
Disruption in the balance between goal-directed behavior and habit learning in obsessive-compulsive disorder
Gillan, C. M., Papmeyer, M., Morein-Zamir, S., Sahakian, B. J., Fineberg, N. A., Robbins, T. W., & de Wit, S. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2011.10071062 · Cited by 609
Altered corticostriatal functional connectivity in obsessive-compulsive disorder
Harrison, B. J., Soriano-Mas, C., Pujol, J., Ortiz, H., López-Solà, M., Hernández-Ribas, R., Deus, J., Alonso, P., Yücel, M., Pantelis, C., et al. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.152 · Cited by 571
Neurocognitive endophenotypes of obsessive-compulsive disorder
Menzies, L., Achard, S., Chamberlain, S. R., Fineberg, N., Chen, C.-H., del Campo, N., Sahakian, B. J., Robbins, T. W., & Bullmore, E. (2007) · Brain · doi:10.1093/brain/awm205 · Cited by 443
Obsessive-compulsive disorder: a review of the diagnostic criteria and possible subtypes and dimensional specifiers for DSM-V
Leckman, J. F., Denys, D., Simpson, H. B., Mataix-Cols, D., Hollander, E., Saxena, S., Miguel, E. C., Rauch, S. L., Goodman, W. K., Phillips, K. A., et al. (2010) · Depression and Anxiety · doi:10.1002/da.20669 · Cited by 411
Self-citation
The neural bases of obsessive-compulsive disorder in children and adults
Maia, T. V., Cooney, R. E., & Peterson, B. S. (2008) · Development and Psychopathology · doi:10.1017/s0954579408000606 · Cited by 362
“A more recent study using the same paradigm confirmed abnormal recruitment of the hippocampus in patients with OCD, even though it failed to detect differences in activation of the striatum between patients with OCD and healthy controls (Rauch et al., 2007).”
Background
Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice
Shmelkov, S. V., Hormigo, A., Jing, D., Proenca, C. C., Bath, K. G., Milde, T., Shmelkov, E., Kushner, J. S., Baljevic, M., Dincheva, I., et al. (2010) · Nature Medicine · doi:10.1038/nm.2125 · Cited by 361
Invasive circuitry-based neurotherapeutics: stereotactic ablation and deep brain stimulation for OCD
Greenberg, B. D., Rauch, S. L., & Haber, S. N. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.128 · Cited by 359
Self-citation
Dysfunctional reward circuitry in obsessive-compulsive disorder
Figee, M., Vink, M., de Geus, F., Vulink, N., Veltman, D. J., Westenberg, H., & Denys, D. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.12.003 · Cited by 315
The Role of the Orbitofrontal Cortex in Anxiety Disorders
Milad, M. R., & Rauch, S. L. (2007) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1401.006 · Cited by 329
Self-citation
Deficits in Conditioned Fear Extinction in Obsessive-Compulsive Disorder and Neurobiological Changes in the Fear Circuit
Milad, M. R., Furtak, S. C., Greenberg, J. L., Keshaviah, A., Im, J. J., Falkenstein, M. J., Jenike, M., Rauch, S. L., & Wilhelm, S. (2013) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.914 · Cited by 308
Self-citation
Resting-state functional connectivity between fronto-parietal and default mode networks in obsessive-compulsive disorder
Stern, E. R., Fitzgerald, K. D., Welsh, R. C., Abelson, J. L., & Taylor, S. F. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036356 · Cited by 245
A compensatory role for declarative memory in neurodevelopmental disorders
Ullman, M. T., & Pullman, M. Y. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.01.008 · Cited by 263
Learning-related coordination of striatal and hippocampal theta rhythms during acquisition of a procedural maze task
DeCoteau, W. E., Thorn, C. A., Gibson, D. J., Courtemanche, R., Mitra, P. P., Kubota, Y., & Graybiel, A. M. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700818104 · Cited by 261
Brain corticostriatal systems and the major clinical symptom dimensions of obsessive-compulsive disorder
Harrison, B. J., Pujol, J., Cardoner, N., Deus, J., Alonso, P., López-Solà, M., Contreras-Rodríguez, O., Real, E., Segalàs, C., Blanco-Hinojo, L., et al. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.10.006 · Cited by 234
Procedural learning is impaired in dyslexia: Evidence from a meta-analysis of serial reaction time studies
Lum, J. A. G., Ullman, M. T., & Conti‐Ramsden, G. (2013) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2013.07.017 · Cited by 215
Procedural learning deficits in specific language impairment (SLI): A meta-analysis of serial reaction time task performance
Lum, J. A. G., Conti‐Ramsden, G., Morgan, A. T., & Ullman, M. T. (2013) · Cortex · doi:10.1016/j.cortex.2013.10.011 · Cited by 217
Should OCD be classified as an anxiety disorder in DSM-V?
Stein, D. J., Fineberg, N. A., Bienvenu, O. J., Denys, D., Lochner, C., Nestadt, G., Leckman, J. F., Rauch, S. L., & Phillips, K. A. (2010) · Depression and Anxiety · doi:10.1002/da.20699 · Cited by 212
Self-citation
Functional neuroimaging in obsessive-compulsive disorder
Del Casale, A., Kotzalidis, G. D., Rapinesi, C., Serata, D., Ambrosi, E., Simonetti, A., Pompili, M., Ferracuti, S., Tatarelli, R., & Girardi, P. (2011) · Neuropsychobiology · doi:10.1159/000325223 · Cited by 210
Intact implicit learning in autism spectrum conditions
Brown, J., Aczél, B., Jiménez, L., Kaufman, S. B., & Grant, K. P. (2010) · Quarterly Journal of Experimental Psychology · doi:10.1080/17470210903536910 · Cited by 190
Imbalance in habitual versus goal directed neural systems during symptom provocation in obsessive-compulsive disorder
Banca, P., Voon, V., Vestergaard, M. D., Philipiak, G., Almeida, I., Pocinho, F., Relvas, J., & Castelo-Branco, M. (2015) · Brain · doi:10.1093/brain/awu379 · Cited by 148
Activation in striatum and medial temporal lobe during sequence learning in younger and older adults: Relations to performance
Rieckmann, A., Fischer, H., & Bäckman, L. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.01.015 · Cited by 141
Decreased limbic and increased fronto‐parietal connectivity in unmedicated patients with obsessive‐compulsive disorder
Göttlich, M., Krämer, U. M., Kordon, A., Hohagen, F., & Zurowski, B. (2014) · Human Brain Mapping · doi:10.1002/hbm.22574 · Cited by 123
Slitrks as emerging candidate genes involved in neuropsychiatric disorders
Proenca, C. C., Gao, K. P., Shmelkov, S. V., Rafii, S., & Lee, F. S. (2011) · Trends in Neurosciences · doi:10.1016/j.tins.2011.01.001 · Cited by 120
Paediatric obsessive-compulsive disorder, a neurodevelopmental disorder?
Huyser, C., Veltman, D. J., de Haan, E., & Boer, F. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.01.003 · Cited by 108
Voxel-Based Morphometry Study of Gray Matter Abnormalities in Obsessive-Compulsive Disorder
Yoo, S. Y., Roh, M., Choi, J., Kang, D.-H., Ha, T. H., Lee, J., Kim, I. Y., Kim, S. I., & Kwon, J. S. (2008) · Journal of Korean Medical Science · doi:10.3346/jkms.2008.23.1.24 · Cited by 107
Symptom dimensions and subtypes of obsessive-compulsive disorder: a developmental perspective
Leckman, J. F., Bloch, M. H., & King, R. A. (2009) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2009.11.1/jfleckman · Cited by 108
Neural correlates of altered response inhibition and dysfunctional connectivity at rest in obsessive–compulsive disorder
Kang, D.-H., Jang, J. H., Han, J. Y., Kim, J.-H., Jung, W. H., Choi, J.-S., Choi, C.-H., & Kwon, J. S. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2012.11.001 · Cited by 105
Implicit Learning in Aging: Extant Patterns and New Directions
Rieckmann, A., & Bäckman, L. (2009) · Neuropsychology Review · doi:10.1007/s11065-009-9117-y · Cited by 99
Searching for an anchor in an unpredictable world: A computational model of obsessive-compulsive disorder
Fradkin, I., Adams, R. A., Parr, T., Roiser, J. P., & Huppert, J. D. (2020) · Psychological Review · doi:10.1037/rev0000188 · Cited by 89
Cognitive inflexibility and frontal–cortical activation in pediatric obsessive–compulsive disorder
Britton, J. C., Rauch, S. L., Rosso, I. M., Killgore, W. D. S., Price, L. M., Ragan, J., Chosak, A., Hezel, D. M., Pine, D. S., Leibenluft, E., et al. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2010.05.006 · Cited by 92
Self-citation
Motivation and value influences in the relative balance of goal-directed and habitual behaviours in obsessive-compulsive disorder
Voon, V., Baek, K., Enander, J., Worbe, Y., Morris, L. S., Harrison, N. A., Robbins, T. W., Rück, C., & Daw, N. D. (2015) · Translational Psychiatry · doi:10.1038/tp.2015.165 · Cited by 91
Subcortical and cortical morphological anomalies as an endophenotype in obsessive-compulsive disorder
Shaw, P., Sharp, W. S., Sudre, G. P., Wharton, A., GREENSTEIN, D. K., Raznahan, A., Evans, A. C., Chakravarty, M. M., Lerch, J. P., & Rapoport, J. L. (2014) · Molecular Psychiatry · doi:10.1038/mp.2014.3 · Cited by 89
The involvement of the orbitofrontal cortex in psychiatric disorders: an update of neuroimaging findings
Jackowski, A. P., Filho, G. M. D. A., Almeida, A. G.-D., de Araújo, C. M., dos Reis, M. A., Nery, F., Batista, I. R., Silva, I., & Lacerda, A. L. T. (2012) · Brazilian Journal of Psychiatry · doi:10.1590/s1516-44462012000200014 · Cited by 85
Hypoactivation and Dysconnectivity of a Frontostriatal Circuit During Goal-Directed Planning as an Endophenotype for Obsessive-Compulsive Disorder
Vaghi, M. M. S., Hampshire, A., Fineberg, N. A., Kaşer, M., Brühl, A. B., Sahakian, B. J., Chamberlain, S. R., & Robbins, T. W. (2017) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2017.05.005 · Cited by 86
Altered activation in fronto-striatal circuits during sequential processing of conflict in unmedicated adults with obsessive-compulsive disorder
Marsh, R., Horga, G., Parashar, N., Wang, Z., Peterson, B. S., & Simpson, H. B. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2013.02.004 · Cited by 79
Motor Learning in Individuals With Autism Spectrum Disorder: Activation in Superior Parietal Lobule Related to Learning and Repetitive Behaviors
Travers, B. G., Kana, R. K., Klinger, L. G., Klein, C. L., & Klinger, M. R. (2014) · Autism Research · doi:10.1002/aur.1403 · Cited by 77
Immune system and obsessive-compulsive disorder
Marazziti, D., Mucci, F., & Fontenelle, L. F. (2018) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2018.04.013 · Cited by 82
Cerebral activation in children and adolescents with obsessive–compulsive disorder before and after treatment: A functional MRI study
Lázaro, L., Caldú, X., Junqué, C., Bargalló, N., Andrés, S., Morer, A., & Castro-Fornieles, J. (2008) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2007.12.007 · Cited by 74
The role of the lateral orbitofrontal cortex in creating cognitive maps
Costa, K. M., Scholz, R., Lloyd, K., Moreno‐Castilla, P., Gardner, M., Dayan, P., & Schoenbaum, G. M. (2022) · Nature Neuroscience · doi:10.1038/s41593-022-01216-0 · Cited by 78
Symptom Dimensions in Obsessive-Compulsive Disorder:Implications for theDSM-V
Leckman, J. F., Rauch, S. L., & Mataix‐Cols, D. (2007) · CNS Spectrums · doi:10.1017/s1092852900021179 · Cited by 73
Self-citation
Ritual Behavior in Obsessive and Normal Individuals: Moderating Anxiety and Reorganizing the Flow of Action
Boyer, P., & Liénard, P. (2008) · Current Directions in Psychological Science · doi:10.1111/j.1467-8721.2008.00592.x · Cited by 65
Executive functions in obsessive–compulsive disorder: an activation likelihood estimate meta-analysis of fMRI studies
Del Casale, A., Rapinesi, C., Kotzalidis, G. D., De Rossi, P., Curto, M., Janiri, D., Criscuolo, S., Alessi, M. C., Ferri, V. R., De Giorgi, R., et al. (2016) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2015.1102323 · Cited by 63
Executive functions and the obsessive-compulsive disorder: on the importance of subclinical symptoms and other concomitant factors
Bedard, M.-J., Joyal, C. C., Godbout, L., & Chantal, S. (2009) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/acp052 · Cited by 62
Arbitration between action strategies in obsessive-compulsive disorder
Gruner, P., Anticevic, A., Lee, D., & Pittenger, C. (2016) · The Neuroscientist · doi:10.1177/1073858414568317 · Cited by 62
Neurocognitive Performance in Children with ADHD and OCD
Vloet, T. D., Marx, I., Kahraman-Lanzerath, B., Zepf, F. D., Herpertz-Dahlmann, B., & Konrad, K. (2010) · Journal of Abnormal Child Psychology · doi:10.1007/s10802-010-9422-1 · Cited by 58
Impaired implicit learning and reduced pre-supplementary motor cortex size in early-onset major depression with melancholic features
Exner, C., Lange, C., & Irle, E. (2009) · Journal of Affective Disorders · doi:10.1016/j.jad.2009.03.015 · Cited by 61
OCD is associated with an altered association between sensorimotor gating and cortical and subcortical 5-HT1b receptor binding
Pittenger, C., Adams, T. G., Gallezot, J., Crowley, M. J., Nabulsi, N., Ropchan, J., Gao, H., Kichuk, S. A., Simpson, R., Billingslea, E., et al. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.02.021 · Cited by 55
Long-term follow-up of patients with obsessive–compulsive disorder treated by anterior capsulotomy: A neuropsychological study
Csigó, K., Harsányi, A., Demeter, G., Rajkai, C., Németh, A., & Racsmány, M. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.02.127 · Cited by 57
Fronto-striatal correlates of impaired implicit sequence learning in major depression: An fMRI study
Naismith, S. L., Lagopoulos, J., Ward, P. B., Davey, C. G., Little, C. L., & Hickie, I. B. (2010) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.02.114 · Cited by 57
Impaired visuospatial associative memory and attention in obsessive compulsive disorder but no evidence for differential dopaminergic modulation
Morein-Zamir, S., Craig, K. J., Ersche, K. D., Abbott, S., Muller, U., Fineberg, N. A., Bullmore, E. T., Sahakian, B. J., & Robbins, T. W. (2010) · Psychopharmacology · doi:10.1007/s00213-010-1963-z · Cited by 54
Altered intrinsic insular activity predicts symptom severity in unmedicated obsessive-compulsive disorder patients: a resting state functional magnetic resonance imaging study
Zhu, Y., Fan, Q., Zhang, H., Qiu, J., Tan, L., Xiao, Z., Tong, S., Chen, J., & Li, Y. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0806-9 · Cited by 56
Reward-based spatial learning in unmedicated adults with obsessive-compulsive disorder
Marsh, R., Tau, G. Z., Wang, Z., Huo, Y., Liu, G., Hao, X., Packard, M. G., Peterson, B. S., & Simpson, H. B. (2015) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2014.13121700 · Cited by 53
Brain activation during cognitive planning in twins discordant or concordant for obsessive-compulsive symptoms
den Braber, A., Ent, D. V. ‘., Cath, D. C., Wagner, J., Boomsma, D. I., & de Geus, E. J. C. (2010) · Brain · doi:10.1093/brain/awq229 · Cited by 51
An initial investigation of the orbitofrontal cortex hyperactivity in obsessive-compulsive disorder: Exaggerated representations of anticipated aversive events?
Ursu, S., & Carter, C. S. (2009) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2009.03.018 · Cited by 49
Enhanced Recognition Memory after Incidental Encoding in Children with Developmental Dyslexia
Hedenius, M., Ullman, M. T., Alm, P. A., Jennische, M., & Persson, J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0063998 · Cited by 54
Punishment promotes response control deficits in obsessive-compulsive disorder: evidence from a motivational go/no-go task
Morein-Zamir, S., Papmeyer, M., Gillan, C. M., Crockett, M. J., Fineberg, N. A., Sahakian, B. J., & Robbins, T. W. (2013) · Psychological Medicine · doi:10.1017/s0033291712001018 · Cited by 43
Altered Cortico-Striatal Functional Connectivity in Obsessive-Compulsive Disorder
Harrison, B. J., Soriano‐Mas, C., Pujol, J., Ortiz, H., López‐Solà, M., Hernández‐Ribas, R., Deus, J., Alonso, P., Yücel, M., Pantelis, C., et al. (2009) · NeuroImage · doi:10.1016/s1053-8119(09)70103-x · Cited by 46
Functional connectivity in obsessive-compulsive disorder and its subtypes
Ravindran, A. V., Richter, M. A., Jain, T., Ravindran, L. N., Rector, N. A., & Farb, N. A. S. (2019) · Psychological Medicine · doi:10.1017/s0033291719001090 · Cited by 45
Disgust affects TNF-α, IL-6 and noradrenalin levels in patients with obsessive–compulsive disorder
Fluitman, S. B. A. H. A., Denys, D. A. J. P., Heijnen, C. J., & Westenberg, H. G. M. (2009) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2009.12.005 · Cited by 46
Stress-induced changes in sleep and associated neuronal activity in rat hippocampus and amygdala
Hegde, P., Singh, K., Chaplot, S. P., Rao, B. S. S., Chattarji, S., Kutty, B. M., & Laxmi, T. R. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.01.042 · Cited by 44
Deficits in auditory P50 inhibition in obsessive-compulsive disorder
Hashimoto, T., Shimizu, E., Koike, K., Orita, Y., Suzuki, T., Kanahara, N., Matsuzawa, D., Fukami, G., Miyatake, R., Shinoda, N., et al. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.08.021 · Cited by 41
Brain activation during implicit sequence learning in individuals with trichotillomania.
Rauch, S., Wright, C. I., Savage, C., Martis, B., McMullin, K., Wedig, M., Gold, A. L., & Keuthen, N. (2007) · Psychiatry Research · doi:10.1016/j.pscychresns.2006.09.002 · Cited by 38
Self-citation
Neuromodulation of OCD: a review of invasive and non-invasive methods
Kammen, A., Cavaleri, J., Lam, J., Frank, A. C., Mason, X., Choi, W., Penn, M., Brasfield, K., Van Noppen, B., Murray, S. B., et al. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2022.909264 · Cited by 38
Cognitive Neuroscience of Obsessive-Compulsive Disorder
Stern, E. R., & Taylor, S. F. (2014) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2014.05.004 · Cited by 40
Reduction of N-acetylaspartate in the medial prefrontal cortex correlated with symptom severity in obsessive-compulsive disorder: meta-analyses of 1H-MRS studies
Aoki, Y. Y., Aoki, A., & Suwa, H. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.78 · Cited by 37
From Thought to Action: How the Interplay Between Neuroscience and Phenomenology Changed Our Understanding of Obsessive-Compulsive Disorder
Barahona-Corrêa, B., Camacho, M., Castro-Rodrigues, P., Costa, R. M., & Oliveira-Maia, A. J. (2015) · Frontiers in Psychology · doi:10.3389/fpsyg.2015.01798 · Cited by 37
An fMRI investigation of the fronto-striatal learning system in women who exhibit eating disorder behaviors
Celone, K., Thompson‐Brenner, H., Ross, R. S., Pratt, E. M., & Stern, C. E. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.03.026 · Cited by 35
Oral N-acetylcysteine in the treatment of obsessive-compulsive disorder: A systematic review of the clinical evidence
Couto, J. P., & Moreira, R. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.06.005 · Cited by 34
Strain and sex based characterization of behavioral expressions in non-induced compulsive-like mice
Mitra, S., Bastos, C. P., Chesworth, S., Frye, C. A., & Bult‐Ito, A. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.11.002 · Cited by 35
Memantine augmentation of sertraline in the treatment of symptoms and executive function among patients with obsessive-compulsive disorder: A double-blind placebo-controlled, randomized clinical trial
Askari, S., Mokhtari, S., Shariat, S. V., Shariati, B., Yarahmadi, M., & Shalbafan, M. (2022) · BMC Psychiatry · doi:10.1186/s12888-021-03642-z · Cited by 32
Is Obsessive–Compulsive symptomatology a risk factor for Alzheimer-type dementia?
Döndü, A., Sevincoka, L., Akyol, A., & Tataroğlu, C. (2014) · Psychiatry Research · doi:10.1016/j.psychres.2014.12.010 · Cited by 30
Role of Glutamatergic System in Obsessive-Compulsive Disorder with Possible Therapeutic Implications
Vlček, P., Polák, J., Brunovský, M., & Horáček, J. (2017) · Pharmacopsychiatry · doi:10.1055/s-0043-118665 · Cited by 32
Theta-Burst Repetitive Transcranial Magnetic Stimulation for Treatment-Resistant Obsessive-Compulsive Disorder With Concomitant Depression
Wu, C., Tsai, C., Lu, M., Chen, C., Shen, W., & Su, K. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.09l05426blu · Cited by 29
Clinical features of pure obsessive-compulsive disorder
Torres, A. R., Shavitt, R. G., Torresan, R. C., Ferrão, Y. A., Miguel, E. C., & Fontenelle, L. F. (2013) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2013.04.013 · Cited by 36
Neuregulin 3 Signaling Mediates Nicotine-Dependent Synaptic Plasticity in the Orbitofrontal Cortex and Cognition
Zhou, L., Fisher, M. L., Cole, R. D., Gould, T. J., Parikh, V., Ortinski, P. I., & Turner, J. R. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.278 · Cited by 29
Functional connectivity changes and symptoms improvement after personalized, double-daily dosing, repetitive transcranial magnetic stimulation in obsessive-compulsive disorder: A pilot study
Mantovani, A., Neri, F., D’Urso, G., Mencarelli, L., Tatti, E., Momi, D., Menardi, A., Sprugnoli, G., Santarnecchi, E., & Rossi, S. (2020) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2020.10.030 · Cited by 28
Impaired P50 suppression in fear extinction in obsessive–compulsive disorder
Nanbu, M., Kurayama, T., Nakazawa, K., Matsuzawa, D., Komiya, Z., Haraguchi, T., Ogura, H., Hashimoto, T., Yoshida, S., Iyo, M., et al. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.12.005 · Cited by 27
Explicit instructions facilitate performance of OCD participants but impair performance of non-OCD participants on a serial reaction time task
Soref, A., Liberman, N., Amitai Abramovitch, A., & Dar, R. (2018) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2018.02.003 · Cited by 27
Heart rate after trauma and the specificity of fear circuitry disorders
Bryant, R. A., Creamer, M., O'Donnell, M. L., Silove, D. M., & McFARLANE, A. C. (2011) · Psychological Medicine · doi:10.1017/s0033291711000948 · Cited by 25
Alterations in resting-state local functional connectivity in obsessive-compulsive disorder
Hao, H., Chen, C., Mao, W., Xia, W., Yi, Z., Zhao, P., Pan, P., & Dai, Z. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.10.112 · Cited by 26
A voxel-based morphometric MRI study of stabilized obsessive–compulsive adolescent patients
Lázaro, L., Castro‐Fornieles, J., Cullell, C., Andrés, S., Falcón, C., Calvo, R. M., & Bargalló, N. (2011) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2011.07.016 · Cited by 24
Research Paper: Neuropsychological Functioning in Obsessive-Compulsive Washers: Drug-Naive Without Depressive Symptoms
Saremi, A. A., Department of Cognitive Neuroscience, I. F. C. S. S. (., Shariat, S. V., Mental Health Research Center, T. I. O. P., Nazari, M. A., Department of Psychology, F. O. E. &. P., Dolatshahi, B., & Department of Psychology, U. O. S. W. A. R. S. (2017) · Basic and Clinical Neuroscience Journal · doi:10.18869/nirp.bcn.8.3.233 · Cited by 22
Neurobiología del trastorno obsesivo-compulsivo: aportaciones desde la resonancia magnética funcional (II)
Pena-Garijo, J., Rodríguez, M. Á. R., & Loscertales, A. B. (2010) · Revista de Neurología · doi:10.33588/rn.5009.2010154 · Cited by 22
Feedback associated with expectation for larger-reward improves visuospatial working memory performances in children with ADHD
Hammer, R., Tennekoon, M., Cooke, G. E., Gayda, J., Stein, M. A., & Booth, J. R. (2015) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2015.06.002 · Cited by 21
Video telemetry and behavioral analysis discriminate between compulsive cleaning and compulsive checking in obsessive-compulsive disorder
Zor, R., Fineberg, N. A., Eilam, D., & Hermesh, H. (2011) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2011.03.006 · Cited by 21
Study of symptom dimensions and clinical characteristics in Chinese patients with OCD
Zhang, X., Liu, J., Cui, J., & Liu, C. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.07.025 · Cited by 20
A closer look to neural pathways and psychopharmacology of obsessive compulsive disorder
Gargano, S. P., Santos, M. G., Taylor, S. M., & Pastis, I. (2023) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2023.1282246 · Cited by 18
Effects of glutamate-related drugs on anxiety and compulsive behavior in rats with obsessive-compulsive disorder
Zhan, Y., Xia, J., & Wang, X. (2019) · International Journal of Neuroscience · doi:10.1080/00207454.2019.1684276 · Cited by 21
Obsessive–Compulsive Disorder
Vahabzadeh, A. B. N., & McDougle, C. J. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-386456-7.05213-8 · Cited by 18
Implicit sequence learning in juvenile anorexia nervosa: neural mechanisms and the impact of starvation
Firk, C., Mainz, V., Schulte‐Rüther, M., Fink, G. R., Herpertz‐Dahlmann, B., & Konrad, K. (2015) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12384 · Cited by 16
Probing implicit learning in obsessive-compulsive disorder: Moderating role of medication on the weather prediction task
Kelmendi, B., Adams, T. G., Jakubovski, E., Hawkins, K. A., Coric, V., & Pittenger, C. (2016) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2016.03.003 · Cited by 16
Spontaneous neural activity in the right fusiform gyrus and putamen is associated with consummatory anhedonia in obsessive compulsive disorder
Du, H., Xia, J., Fan, J., Gao, F., Wang, X., Han, Y., Tan, C., & Zhu, X. (2022) · Brain Imaging and Behavior · doi:10.1007/s11682-021-00619-0 · Cited by 14
The cytokine profile of OCD: pathophysiological insights
Marazziti, D., Lombardi, A., Falaschi, V., Dell’Osso, L., & Mucci, F. (2015) · International Journal of Interferon Cytokine and Mediator Research · doi:10.2147/ijicmr.s76710 · Cited by 15
Connectivity Patterns of Deep Brain Stimulation Targets in Patients with Gilles de la Tourette Syndrome
Heiden, P., Hoevels, M., Bayram, D., Baldermann, J. C., Schüller, T., Huys, D., Visser-Vandewalle, V. E. R. M., & Andrade, P. (2021) · Brain Sciences · doi:10.3390/brainsci11010087 · Cited by 14
Structural and functional brain imaging after treatment with selective-serotonin reuptake-inhibitors in obsessive-compulsive disorder: A mini review
Bracco, L., Dusi, N., Moltrasio, C., Brambilla, P., & Delvecchio, G. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.10.034 · Cited by 14
Habitual or hyper-controlled behavior: OCD symptoms and explicit sequence learning
Barzilay, S., Fradkin, I., & Huppert, J. D. (2022) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2022.101723 · Cited by 15

Authors: Rauch, S. L., Wedig, M. M., Wright, C. I., Martis, B., McMullin, K. G., Shin, L. M., Cannistraro, P. A., & Wilhelm, S.
Affiliations: Harvard University (US)
Brigham and Women's Hospital (US)
University of Michigan (US)
Tufts University (US)
Corresponding author: Rauch, Scott L.
ORCID: Rauch, Scott L.
Wright, Christopher I.
Shin, Lisa M.
Wilhelm, Sabine
Venue: Biological Psychiatry
Publisher: Elsevier BV
Published: 2007-02
Volume: 61
Issue: 3
Pages: 330-336
ISSN: 0006-3223 (ISSN-L)
DOI: 10.1016/j.biopsych.2005.12.012
OpenAlex: W2063217688
Cited by: 167
References: 57
Citations by year: 2026: 2 · 2025: 6 · 2024: 2 · 2023: 4 · 2022: 10 · 2021: 6 · 2020: 5 · 2019: 7 · 2018: 7 · 2017: 7 · 2016: 10 · 2015: 12 · 2014: 11 · 2013: 11 · 2012: 7
FWCI: 10.69
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Biological Psychiatry (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5t32eb001632-05, 5r01mh060219-05)
National Institute of Mental Health (K23MH64806, K23MH064806, R01MH60219)
National Institute of Biomedical Imaging and Bioengineering (T32EB001632-01)
Topics: Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
Keywords: obsessive-compulsive disorder, implicit sequence learning, serial reaction time task, striatal activation, orbitofrontal cortex, corticostriatal circuits, OCD symptom dimensions, regional brain activation
MeSH terms: Adult, Brain, Cerebral Cortex, Female, Hippocampus, Humans, Learning, Magnetic Resonance Imaging, Male, Neural Pathways, Obsessive-Compulsive Disorder, Psychomotor Performance, Reaction Time, Recruitment, Neurophysiological, Cohort Studies, Neostriatum

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Functional magnetic resonance imaging study of regional brain activation during implicit sequence learning in obsessive-compulsive disorder

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks