Analyzing Schizophrenia by DNA Microarrays

Mapping and quantifying mammalian transcriptomes by RNA-Seq

Mortazavi, A., Williams, B. A., McCue, K., Schaeffer, L., & Wold, B. (2008) · Nature Methods · doi:10.1038/nmeth.1226 · Cited by 13,696 · see citing works

Gene Expression Omnibus: NCBI gene expression and hybridization array data repository

Edgar, R. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.1.207 · Cited by 13,288 · see citing works

RNA-Seq: a revolutionary tool for transcriptomics

Wang, Z., Gerstein, M., & Snyder, M. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2484 · Cited by 13,174 · see citing works

Next-generation DNA sequencing

Shendure, J., & Ji, H. (2008) · Nature Biotechnology · doi:10.1038/nbt1486 · Cited by 4,509 · see citing works

Minimum information about a microarray experiment (MIAME)-toward standards for microarray data

Brazma, A., Hingamp, P., Quackenbush, J., Sherlock, G., Spellman, P., Stoeckert, C., Aach, J., Ansorge, W., Ball, C. A., Causton, H. C., et al. (2001) · Nature Genetics · doi:10.1038/ng1201-365 · Cited by 4,109 · see citing works

Serial Analysis of Gene Expression

Velculescu, V. E., Zhang, L., Vogelstein, B., & Kinzler, K. W. (1995) · Science · doi:10.1126/science.270.5235.484 · Cited by 3,713 · see citing works

RNA-seq: An assessment of technical reproducibility and comparison with gene expression arrays

Marioni, J. C., Mason, C. E., Mane, S. M., Stephens, M., & Gilad, Y. (2008) · Genome Research · doi:10.1101/gr.079558.108 · Cited by 2,771 · see citing works

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

Harrison, P. J., & Weinberger, D. R. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001558 · Cited by 2,020 · see citing works

Neuregulin 1 and Susceptibility to Schizophrenia

Stefánsson, H., Pétursson, H., Sigurðsson, E., Steinthórsdóttir, V., Bjornsdottir, S., Sigmundsson, T., Ghosh, S., Brynjolfsson, J., Gunnarsdottir, S., Ivarsson, O., et al. (2002) · The American Journal of Human Genetics · doi:10.1086/342734 · Cited by 1,671 · see citing works

Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays.

Brenner, S., Johnson, M., Bridgham, J., Golda, G., Lloyd, D. H., Johnson, D., Luo, S., McCurdy, S., Foy, M., Ewan, M., et al. (2000) · Nature Biotechnology · doi:10.1038/76469 · Cited by 1,360 · see citing works

Understanding alternative splicing: towards a cellular code

Matlin, A. J., Clark, F., & Smith, C. W. J. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1645 · Cited by 1,299 · see citing works

Disruption of two novel genes by a translocation co-segregating with schizophrenia

Millar, J. K. (2000) · Human Molecular Genetics · doi:10.1093/hmg/9.9.1415 · Cited by 1,254 · see citing works

Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia

Hakak, Y., Walker, J. R., Li, C., Wong, W. H., Davis, K. L., Buxbaum, J. D., Haroutunian, V., & Fienberg, A. A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.081071198 · Cited by 1,192 · see citing works

Mitochondria in neuroplasticity and neurological disorders

Mattson, M. P., Gleichmann, M., & Cheng, A. (2008) · Neuron · doi:10.1016/j.neuron.2008.10.010 · Cited by 1,081 · see citing works

Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

Ishihara, N., Nomura, M., Jofuku, A., Kato, H., Suzuki, S. O., Masuda, K., Otera, H., Nakanishi, Y., Nonaka, I., Goto, Y.-I., et al. (2009) · Nature Cell Biology · doi:10.1038/ncb1907 · Cited by 1,066 · see citing works

Gene Expression Deficits in a Subclass of GABA Neurons in the Prefrontal Cortex of Subjects with Schizophrenia

Hashimoto, T., Volk, D. W., Eggan, S. M., Mirnics, K., Pierri, J. N., Sun, Z., Sampson, A. R., & Lewis, D. A. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-15-06315.2003 · Cited by 938 · see citing works

Molecular Characterization of Schizophrenia Viewed by Microarray Analysis of Gene Expression in Prefrontal Cortex

Mirnics, K., Middleton, F. A., Marquez, A., Lewis, D. A., & Levitt, P. (2000) · Neuron · doi:10.1016/s0896-6273(00)00085-4 · Cited by 882 · see citing works

Genetic Variation in the 6p22.3 Gene DTNBP1, the Human Ortholog of the Mouse Dysbindin Gene, Is Associated with Schizophrenia

Straub, R. E., Jiang, Y., MacLean, C. J., Ma, Y., Webb, B. T., Myakishev, M. V., Harris‐Kerr, C., Wormley, B., Sadek, H., Kadambi, B., et al. (2002) · The American Journal of Human Genetics · doi:10.1086/341750 · Cited by 857 · see citing works

Cap analysis gene expression for high-throughput analysis of transcriptional starting point and identification of promoter usage

Shiraki, T., Kondo, S., Katayama, S., Waki, K., Kasukawa, T., Kawaji, H., Kodzius, R., Watahiki, A., Nakamura, M., Arakawa, T., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2136655100 · Cited by 772 · see citing works

ArrayExpress--a public database of microarray experiments and gene expression profiles

Parkinson, H., Kapushesky, M., Shojatalab, M., Abeygunawardena, N., Coulson, R., Farne, A., Holloway, E., Kolesnykov, N., Lilja, P., Lukk, M., et al. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl995 · Cited by 754 · see citing works

Functional organization of the transcriptome in human brain

Oldham, M. C., Konopka, G., Iwamoto, K., Langfelder, P., Kato, T., Horvath, S., & Geschwind, D. H. (2008) · Nature Neuroscience · doi:10.1038/nn.2207 · Cited by 752 · cited 1× · see citing works

Gene expression profiles of laser-captured adjacent neuronal subtypes

Luo, L., Salunga, R. C., Guo, H., Bittner, A., Joy, K. C., Galindo, J. E., Xiao, H., Rogers, K. E., Wan, J. S., Jackson, M. R., et al. (1999) · Nature Medicine · doi:10.1038/4806 · Cited by 691 · see citing works

Advanced sequencing technologies: methods and goals

Shendure, J., Mitra, R. D., Varma, C., & Church, G. M. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1325 · Cited by 559 · see citing works

An RNA map predicting Nova-dependent splicing regulation

Ule, J., Stefani, G., Mele, A., Ruggiu, M., Wang, X., Taneri, B., Gaasterland, T., Blencowe, B. J., & Darnell, R. B. (2006) · Nature · doi:10.1038/nature05304 · Cited by 528 · see citing works

Novel RNAs Identified From an In-Depth Analysis of the Transcriptome of Human Chromosomes 21 and 22Preprint

Kampa, D., Cheng, J., Kapranov, P., Yamanaka, M., Brubaker, S., Cawley, S. E., Drenkow, J., Piccolboni, A., Bekiranov, S., Helt, G. A., et al. (2004) · Genome Research · doi:10.1101/gr.2094104 · Cited by 527 · see citing works

[19] Gene Expression Omnibus: Microarray Data Storage, Submission, Retrieval, and Analysis

Barrett, T., & Edgar, R. (2006) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(06)11019-8 · Cited by 511 · see citing works

Schizophrenia

Carpenter, W. T., & Buchanan, R. W. (1994) · New England Journal of Medicine · doi:10.1056/nejm199403103301006 · Cited by 510 · see citing works

Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis

Iwamoto, K., Bundo, M., & Kato, T. (2004) · Human Molecular Genetics · doi:10.1093/hmg/ddi022 · Cited by 496 · see citing works

Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia

Hashimoto, T., Arion, D., Unger, T., Maldonado-Avilés, J. G., Morris, H. M., Volk, D. W., Mirnics, K., & Lewis, D. A. (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002011 · Cited by 490 · see citing works

The neurodevelopmental hypothesis of schizophrenia: Following a trail of evidence from cradle to grave

Marenco, S., & Weinberger, D. R. (2000) · Development and Psychopathology · doi:10.1017/s0954579400003138 · Cited by 482 · see citing works

Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia

Hashimoto, T., Bazmi, H. H., Mirnics, K., Wu, Q., Sampson, A. R., & Lewis, D. A. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07081223 · Cited by 457 · see citing works

Neuregulin 1 and Schizophrenia: Genetics, Gene Expression, and Neurobiology

Harrison, P. J., & Law, A. J. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.11.002 · Cited by 453 · see citing works

Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia

Mirnics, K., Middleton, F. A., Stanwood, G. D., Lewis, D. A., & Levitt, P. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000866 · Cited by 446 · see citing works

Gene Expression Profiling Reveals Alterations of Specific Metabolic Pathways in Schizophrenia

Middleton, F. A., Mirnics, K., Pierri, J. N., Lewis, D. A., & Levitt, P. R. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-07-02718.2002 · Cited by 428 · see citing works

ArrayExpress update--from an archive of functional genomics experiments to the atlas of gene expression

Parkinson, H., Kapushesky, M., Kolesnikov, N. N., Rustici, G., Shojatalab, M., Abeygunawardena, N., Bérubé, H., Dyląg, M., Emam, I., Farne, A., et al. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn889 · Cited by 418 · see citing works

Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5′ SNPs associated with the disease

Law, A. J., Lipska, B. K., Weickert, C. S., Hyde, T. M., Straub, R. E., Hashimoto, R., Harrison, P. J., Kleinman, J. E., & Weinberger, D. R. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602002103 · Cited by 403 · see citing works

Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse

Mirnics, K., Middleton, F. A., Lewis, D. A., & Levitt, P. R. (2001) · Trends in Neurosciences · doi:10.1016/s0166-2236(00)01862-2 · Cited by 393 · see citing works

Association and linkage analyses of RGS4 polymorphisms in schizophrenia

Chowdari, K. V. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.12.1373 · Cited by 368 · see citing works

Human Dysbindin (DTNBP1) Gene Expression inNormal Brain and in Schizophrenic Prefrontal Cortex and Midbrain

Weickert, C. S., Straub, R. E., McClintock, B., Matsumoto, M., Hashimoto, R., Hyde, T. M., Herman, M. M., Weinberger, D. R., & Kleinman, J. E. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.6.544 · Cited by 352 · see citing works

A global map of human gene expression

Lukk, M., Kapushesky, M., Nikkilä, J., Parkinson, H., Gonçalves, Â., Huber, W. K., Ukkonen, E., & Brāzma, A. (2010) · Nature Biotechnology · doi:10.1038/nbt0410-322 · Cited by 351 · see citing works

The beginning of the end for microarrays?

Shendure, J. (2008) · Nature Methods · doi:10.1038/nmeth0708-585 · Cited by 331 · see citing works

Molecular Evidence for Increased Expression of Genes Related to Immune and Chaperone Function in the Prefrontal Cortex in Schizophrenia

Arion, D., Unger, T. L., Lewis, D. A., Levitt, P. R., & Mirnics, K. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.12.021 · Cited by 328 · see citing works

Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia

Glatt, S. J., Everall, I., Kremen, W. S., Corbeil, J., Šášik, R., Khanlou, N., Han, M., Liew, C., & Tsuang, M. T. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507666102 · Cited by 322 · see citing works

Deficient Hippocampal Neuron Expression of Proteasome, Ubiquitin, and Mitochondrial Genes in Multiple Schizophrenia Cohorts

Altar, C. A., Jurata, L. W., Charles, V., Lemire, A., Liu, P., Bukhman, Y., Young, T. A., Bullard, J., Yokoe, H., Webster, M. J., et al. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.03.031 · Cited by 318 · see citing works

Microarray analysis of postmortem temporal cortex from patients with schizophrenia

Aston, C., Jiang, L., & Sokolov, B. P. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20208 · Cited by 283 · see citing works

Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study

Vawter, M. (2002) · Schizophrenia Research · doi:10.1016/s0920-9964(01)00377-2 · Cited by 275 · see citing works

Inflammation-related genes up-regulated in schizophrenia brains

Saetre, P., Emilsson, L., Axelsson, E., Kreuger, J., Lindholm, E., & JAZIN, E. E. (2007) · BMC Psychiatry · doi:10.1186/1471-244x-7-46 · Cited by 266 · see citing works

A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia

Huffaker, S. J., Chen, J., Nicodemus, K. K., Sambataro, F., Yang, F., Mattay, V. S., Lipska, B. K., Hyde, T. M., Song, J., Rujescu, D., et al. (2009) · Nature Medicine · doi:10.1038/nm.1962 · Cited by 249 · see citing works

In situ localized amplification and contact replication of many individual DNA molecules

Mitra, R. D. (1999) · Nucleic Acids Research · doi:10.1093/nar/27.24.e34 · Cited by 239 · see citing works

A simple spreadsheet-based, MIAME-supportive format for microarray data: MAGE-TAB

Rayner, T. F., Rocca‐Serra, P., Spellman, P. T., Causton, H. C., Farne, A., Holloway, E., Irizarry, R. A., Liu, J., Maier, D. S., Miller, M., et al. (2006) · BMC Bioinformatics · doi:10.1186/1471-2105-7-489 · Cited by 218 · see citing works

The MGED Ontology: a resource for semantics-based description of microarray experiments

Whetzel, P. L., Parkinson, H., Causton, H. C., Fan, L., Fostel, J. M., Fragoso, G., Gamé, L., Heiskanen, M. A., Morrison, N., Rocca‐Serra, P., et al. (2006) · Bioinformatics · doi:10.1093/bioinformatics/btl005 · Cited by 212 · see citing works

GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss

Addington, A. M., Gornick, M., Duckworth, J., Sporn, A. L., Gogtay, N., Bobb, A., GREENSTEIN, D. K., Lenane, M., Gochman, P., Baker, N., et al. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001599 · Cited by 207 · see citing works

Minimum Information About a Microarray Experiment (MIAME) – Successes, Failures, Challenges

Brāzma, A. (2009) · The Scientific World JOURNAL · doi:10.1100/tsw.2009.57 · Cited by 205 · see citing works

Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia

Martins‐de‐Souza, D., Gattaz, W. F., Schmitt, A., Rewerts, C., Maccarrone, G., Dias‐Neto, E., & Turck, C. W. (2009) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-008-0847-2 · Cited by 203 · see citing works

Support for involvement of neuregulin 1 in schizophrenia pathophysiology

Petryshen, T. L., Middleton, F. A., Kirby, A. W., Aldinger, K. A., Purcell, S., Tahl, A. R., Morley, C. P., McGann, L., Gentile, K. L., Rockwell, G. N., et al. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001608 · Cited by 195 · see citing works

Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection

Ruzicka, W. B., Zhubi, A., Veldić, M., Grayson, D. R., Costa, E., & Guidotti, A. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4001954 · Cited by 186 · see citing works

Fluorescent in situ sequencing on polymerase colonies

Mitra, R. D., Shendure, J., Olejnik, J., Edyta-Krzymanska-Olejnik, & Church, G. M. (2003) · Analytical Biochemistry · doi:10.1016/s0003-2697(03)00291-4 · Cited by 183 · see citing works

Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs

Lipska, B. K., Peters, T., Hyde, T. M., Halim, N., Horowitz, C., Mitkus, S., Weickert, C. S., Matsumoto, M., Sawa, A., Straub, R. E., et al. (2006) · Human Molecular Genetics · doi:10.1093/hmg/ddl040 · Cited by 168 · see citing works

Review: The group II metabotropic glutamate receptor 3 (mGluR3, mGlu3, GRM3): expression, function and involvement in schizophrenia

Harrison, P. J., Lyon, L., Sartorius, L. J., Burnet, P., & Lane, T. A. (2008) · Journal of Psychopharmacology · doi:10.1177/0269881108089818 · Cited by 166 · see citing works

Progress in the use of microarray technology to study the neurobiology of disease

Mirnics, K., & Pevsner, J. (2004) · Nature Neuroscience · doi:10.1038/nn1230 · Cited by 150 · see citing works

Critical Appraisal of DNA Microarrays in Psychiatric Genomics

Mirnics, K., Levitt, P. R., & Lewis, D. A. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.02.003 · Cited by 138 · see citing works

Confirming <i>RGS4</i> as a susceptibility gene for schizophrenia

Morris, D. W., Rodgers, A., McGhee, K. A., Schwaiger, S., Scully, P., Quinn, J., Meagher, D., Waddington, J. L., Gill, M., & Corvin, A. P. (2004) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.20109 · Cited by 137 · see citing works

Support for RGS4 as a susceptibility gene for schizophrenia

Williams, N. M., Preece, A. C., Spurlock, G., Norton, N., Williams, H. J., McCreadie, R. G., Buckland, P. R., Sharkey, V., Chowdari, K. V., Zammit, S., et al. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2003.11.002 · Cited by 133 · see citing works

Brain banking: opportunities, challenges and meaning for the future

Kretzschmar, H. A. (2008) · Nature reviews. Neuroscience · doi:10.1038/nrn2535 · Cited by 120 · see citing works

Prefrontal Abnormality of Schizophrenia Revealed by DNA Microarray: Impact on Glial and Neurotrophic Gene Expression

Sugai, T., Kawamura, M., Iritani, S., Araki, K., Makifuchi, T., Imai, C., Nakamura, R., Kakita, A., Takahashi, H., & Nawa, H. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1316.011 · Cited by 115 · see citing works

The organization of the transcriptional network in specific neuronal classes

Winden, K. D., Oldham, M. C., Mirnics, K., Ebert, P. J., Swan, C. H., Levitt, P., Rubenstein, J. L., Horvath, S., & Geschwind, D. H. (2009) · Molecular Systems Biology · doi:10.1038/msb.2009.46 · Cited by 112 · see citing works

Identification of YWHAE, a gene encoding 14-3-3epsilon, as a possible susceptibility gene for schizophrenia

Ikeda, M., Hikita, T., Taya, S., Uraguchi‐Asaki, J., Toyo‐oka, K., Wynshaw-Boris, A. J., Ujike, H., Inada, T., Takao, K., Miyakawa, T., et al. (2008) · Human Molecular Genetics · doi:10.1093/hmg/ddn217 · Cited by 112 · see citing works

Gene Expression Profiling with DNA Microarrays: Advancing Our Understanding of Psychiatric Disorders

Pongrac, J. L., Middleton, F. A., Lewis, D. A., Levitt, P. R., & Mirnics, K. (2002) · Neurochemical Research · doi:10.1023/a:1020904821237 · Cited by 108 · see citing works

The Cerebral Microvasculature in Schizophrenia: A Laser Capture Microdissection Study

Harris, L. W., Wayland, M. T., Lan, M. J., Ryan, M., Giger, T., Lockstone, H. E., Wüthrich, I., Mimmack, M. L., Wang, L., Kotter, M., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003964 · Cited by 104 · see citing works

Variations in oligodendrocyte-related gene expression across multiple cortical regions: implications for the pathophysiology of schizophrenia

Haroutunian, V. H., Katsel, P., Dracheva, S. M., Stewart, D. G., & Davis, K. L. (2007) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145706007310 · Cited by 102 · see citing works

Detection and measurement of alternative splicing using splicing-sensitive microarrays

Srinivasan, K., Shiue, L., Hayes, J. D., Centers, R., Fitzwater, S. P., Loewen, R., Edmondson, L. R., Bryant, J., Smith, M., & Rommelfanger, C. (2005) · Methods · doi:10.1016/j.ymeth.2005.09.007 · Cited by 101 · see citing works

Single-Cell Gene Expression Analysis: Implications for Neurodegenerative and Neuropsychiatric Disorders

Ginsberg, S. D., Elarova, I., Ruben, M., Tan, F., Counts, S. E., Eberwine, J. H., Trojanowski, J. Q., Hemby, S. E., Mufson, E. J., & Che, S. (2004) · Neurochemical Research · doi:10.1023/b:nere.0000023593.77052.f7 · Cited by 97 · see citing works

Regulator of G‐protein signaling 4 (RGS4) gene is associated with schizophrenia in Irish high density families

Chen, X., Dunham, C., Kendler, S., et al. (2004) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30078 · Cited by 96 · see citing works

Association of SNPs and haplotypes in GABAA receptor β2 gene with schizophrenia

Lo, W.-S., Lau, C.-F., Xuan, Z., Chan, C.-F., Feng, G.-Y., He, L., Cao, Z.-C., Liu, H., Luan, Q.-M., & Xue, H. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001461 · Cited by 79 · see citing works

Altered Expression of 14-3-3 Genes in the Prefrontal Cortex of Subjects with Schizophrenia

Middleton, F. A., Peng, L., Lewis, D. A., Levitt, P. R., & Mirnics, K. (2005) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300674 · Cited by 76 · see citing works

Altered gene expression in the superior temporal gyrus in schizophrenia

Bowden, N. A., Scott, R. J., & Tooney, P. A. (2008) · BMC Genomics · doi:10.1186/1471-2164-9-199 · Cited by 74 · see citing works

The Stanley Neuropathology Consortium Integrative Database: a Novel, Web-Based Tool for Exploring Neuropathological Markers in Psychiatric Disorders and the Biological Processes Associated with Abnormalities of Those Markers

Kim, S., & Webster, M. J. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.151 · Cited by 73 · see citing works

Microarrays in brain research: the good, the bad and the ugly

Mirnics, K. (2001) · Nature reviews. Neuroscience · doi:10.1038/35077587 · Cited by 72 · see citing works

Psychosocial competence of unselected young adults with sex chromosome abnormalities

Bender, B. G., Harmon, R. J., Linden, M. G., Bucher‐Bartelson, B., & Robinson, A. (1999) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19990416)88:2 · Cited by 61 · see citing works

Molecular markers distinguishing supragranular and infragranular layers in the human prefrontal cortex

Arion, D., Unger, T. L., Lewis, D. A., & Mirnics, K. (2007) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2007.05396.x · Cited by 60 · see citing works

Synaptic activity-dependent modulation of mitochondrial gene expression in the rat hippocampus

Williams, J. M., Thompson, V. L., Mason‐Parker, S. E., Abraham, W. C., & Tate, W. P. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(98)00165-x · Cited by 58 · see citing works

Elevated GRIA1 mRNA expression in Layer II/III and V pyramidal cells of the DLPFC in schizophrenia

O’Connor, J. A., & Hemby, S. E. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.09.022 · Cited by 53 · see citing works

Recent advances in postmortem pathology and neurochemistry in schizophrenia

Dean, B., Boer, S., Gibbons, A. S., Money, T., & Scarr, E. (2009) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e328323d52e · Cited by 51 · see citing works

Immunohistochemical and immunoblot study of GABAA α1 and β2/3 subunits in the prefrontal cortex of subjects with schizophrenia and bipolar disorder

Ishikawa, M., Mizukami, K., Iwakiri, M., Hidaka, S., & Asada, T. (2004) · Neuroscience Research · doi:10.1016/j.neures.2004.06.006 · Cited by 51 · see citing works

Platform influence on DNA microarray data in postmortem brain research

Hollingshead, D. J., Lewis, D. A., & Mirnics, K. (2005) · Neurobiology of Disease · doi:10.1016/j.nbd.2004.10.020 · Cited by 51 · see citing works

Thalamic transcriptome screening in three psychiatric states

Chu, T., Liu, Y., & Kemether, E. M. (2009) · Journal of Human Genetics · doi:10.1038/jhg.2009.93 · Cited by 51 · see citing works

Genetic and post-mortem mRNA analysis of the 14-3-3 genes that encode phosphoserine/threonine-binding regulatory proteins in schizophrenia and bipolar disorder

Wong, A. H. C., Likhodi, O., Trakalo, J., Yusuf, M., Sinha, A., Pato, C. N., Pato, M. T., Tol, H. H. M. V., & Kennedy, J. L. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2005.06.009 · Cited by 47 · see citing works

An association study between polymorphisms in three genes of 14-3-3 (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein) family and paranoid schizophrenia in northern Chinese population

Jia, Y., Yu, X., Zhang, B., et al. (2004) · European Psychiatry · doi:10.1016/j.eurpsy.2004.07.006 · Cited by 45 · see citing works

Infragranular gene expression disturbances in the prefrontal cortex in schizophrenia: Signature of altered neural development?

Arion, D., Horváth, S., Lewis, D. A., & Mirnics, K. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.12.013 · Cited by 45 · see citing works

Heat shock protein 12A shows reduced expression in the prefrontal cortex of subjects with schizophrenia

Pongrac, J. L., Middleton, F. A., Peng, L., Lewis, D. A., Levitt, P. R., & Mirnics, K. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.09.005 · Cited by 42 · see citing works

Schizophrenia and sex associated differences in the expression of neuronal and oligodendrocyte-specific genes in individual thalamic nuclei

Byne, W. M., Dracheva, S. M., Chin, B., Schmeidler, J., Davis, K. L., & Haroutunian, V. H. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.09.034 · Cited by 36 · see citing works

RGS4 is not a susceptibility gene for schizophrenia in Japanese: Association study in a large case-control population

Ishiguro, H., Horiuchi, Y., Koga, M., Inada, T., Iwata, N., Ozaki, N., Ujike, H., Muratake, T., Someya, T., & Arinami, T. (2006) · Schizophrenia Research · doi:10.1016/j.schres.2006.09.015 · Cited by 35 · see citing works

Novel animal models for studying complex brain disorders: BAC-driven miRNA-mediated in vivo silencing of gene expression

Garbett, K., Horváth, S., Ebert, P., Schmidt, M., Lwin, K., Mitchell, A., Levitt, P., & Mirnics, K. (2010) · Molecular Psychiatry · doi:10.1038/mp.2010.1 · Cited by 35 · see citing works

A cross-laboratory comparison of expression profiling data from normal human postmortem brain

Mistry, M., & Pavlidis, P. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.01.016 · Cited by 33 · see citing works

RGS4 polymorphisms and risk of schizophrenia: An association study in Han Chinese plus meta-analysis

Guo, S., Tang, W. D., Shi, Y., Huang, K., Xi, Z., Xu, Y., Feng, G., & He, L. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.07.028 · Cited by 31 · see citing works

DNA Microarray Analysis of Postmortem Brain Tissue

Mirnics, K., Levitt, P. R., & Lewis, D. A. (2004) · International review of neurobiology · doi:10.1016/s0074-7742(04)60006-7 · Cited by 25 · see citing works

Impact of neuregulin-1 on the pathophysiology of schizophrenia in human post-mortem studies

Schmitt, A., Parlapani, E., Gruber, O., et al. (2008) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-008-5019-x · Cited by 23 · see citing works

Breaking the gene barrier in schizophrenia

Horváth, S., & Mirnics, K. (2009) · Nature Medicine · doi:10.1038/nm0509-488 · Cited by 22 · see citing works

What is in the brain soup?

Mirnics, K. (2008) · Nature Neuroscience · doi:10.1038/nn1108-1237 · Cited by 8 · see citing works

Microarrays in Brain Research: Data Quality and Limitations Revisited

Mirnics, K. (2006) · Current Genomics · doi:10.2174/138920206776389739 · Cited by 4 · see citing works

Gene expression elucidates functional impact of polygenic risk for schizophrenia

Fromer, M., Roussos, P., Sieberts, S. K., Johnson, J. S., Kavanagh, D. H., Perumal, T. M., Ruderfer, D. M., Oh, E. C., Topol, A., Shah, H. R., et al. (2016) · Nature Neuroscience · doi:10.1038/nn.4399 · Cited by 1,091 · see citing works

Epigenetic changes at gene promoters in response to immune activation in utero

Tang, B., Jia, H., Kast, R. J., & Thomas, E. A. (2013) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2013.01.086 · Cited by 91 · see citing works

Targeting G protein coupled receptor-related pathways as emerging molecular therapies

Ghanemi, A. (2015) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2013.07.007 · Cited by 53 · see citing works

Proteome effects of antipsychotic drugs: Learning from preclinical models

Carboni, L., & Domenici, E. (2016) · PROTEOMICS – Clinical Applications · doi:10.1002/prca.201500087 · Cited by 16 · see citing works

Shared probe design and existing microarray reanalysis using PICKY

Chou, H.-H. (2010) · BMC Bioinformatics · doi:10.1186/1471-2105-11-196 · Cited by 25 · see citing works

[Study on development of DNA microarrays for human papillomavirus (HPV) diagnosis].

Liu, C., Ma, W., Bao, Z., et al. (2003) · PubMed · Cited by 1 · see citing works

DNA Microarray Technology

Zhou, J. Z., & Thompson, D. K. (2004) · doi:10.1002/0471647527.ch6 · Cited by 62 · see citing works

Deep learning identifies erroneous microarray-based, gene-level conclusions in literature

Qin, Y., Yi, D., Chen, X., & Guan, Y. (2021) · NAR Genomics and Bioinformatics · doi:10.1093/nargab/lqab089 · Cited by 1 · see citing works

Microarray Analysis of Gene Expression Changes in Aging

Hudson, F. N., Kaeberlein, M. R., Linford, N. J., Pritchard, D. K., Beyer, R., & Rabinovitch, P. S. (2005) · Elsevier eBooks · doi:10.1016/b978-012088387-5/50014-5 · Cited by 4 · see citing works