Cited by 157Algal biology and biofuel productionSeaweed-derived Bioactive CompoundsAquaculture Nutrition and Growth

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Using green alga Haematococcus pluvialis for astaxanthin and lipid co-production: Advances and outlook

Ren, Yuanyuan, Deng, Jinquan, Huang, Junchao, Wu, Zhaoming, Yi, Lanbo, Bi, Yuge, Chen, Feng·2021·Bioresource Technology

DOI 10.1016/j.biortech.2021.125736

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Abstract

Astaxanthin is one of the secondary carotenoids involved in mediating abiotic stress of microalgae. As an important antioxidant and nutraceutical compound, astaxanthin is widely applied in dietary supplements and cosmetic ingredients. However, most astaxanthin in the market is chemically synthesized, which are structurally heterogeneous and inefficient for biological uptake. Astaxanthin refinery from Haematococcus pluvialis is now a growing industrial sector. H. pluvialis can accumulate astaxanthin to ∼5% of dry weight. As productivity is a key metric to evaluate the production feasibility, understanding the biological mechanisms of astaxanthin accumulation is beneficial for further production optimization. In this review, the biosynthesis mechanism of astaxanthin and production strategies are summarized. The current research on enhancing astaxanthin accumulation and the potential joint-production of astaxanthin with lipids was also discussed. It is conceivable that with further improvement on the productivity of astaxanthin and by-products, the algal-derived astaxanthin would be more accessible to low-profit applications.

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See all 157

Authors: Ren, Y., Deng, J., Huang, J., Wu, Z., Yi, L., Bi, Y., & Chen, F.
Affiliations: Shenzhen University (CN)
Corresponding author: Chen, Feng
ORCID: Ren, Yuanyuan
Huang, Junchao
Chen, Feng
Venue: Bioresource Technology
Publisher: Elsevier BV
Published: 2021-11
Volume: 340
Pages: 125736
ISSN: 0960-8524 (ISSN-L)
DOI: 10.1016/j.biortech.2021.125736
OpenAlex: W3188437852
Cited by: 155
References: 147
Citations by year: 2026: 17 · 2025: 38 · 2024: 32 · 2023: 37 · 2022: 27 · 2021: 4
FWCI: 1.27
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
doi.org/10.15223/policy-017 (stm-asf)
doi.org/10.15223/policy-037 (stm-asf)
doi.org/10.15223/policy-012 (stm-asf)
doi.org/10.15223/policy-029 (stm-asf)
doi.org/10.15223/policy-004 (stm-asf)
Locations: Bioresource Technology (publishedVersion)
PubMed (publishedVersion)
Funders: Science, Technology and Innovation Commission of Shenzhen Municipality (KQTD20180412181334790)
National Natural Science Foundation of China (31471717)
Peking University
Shenzhen University
Topics: Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Aquaculture Nutrition and Growth
Keywords: Haematococcus pluvialis, astaxanthin, astaxanthin biosynthesis, astaxanthin accumulation, microalgae, carotenoids, nutraceuticals, production optimization, abiotic stress
MeSH terms: Chlorophyceae, Lipids, Xanthophylls, Microalgae

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Using green alga Haematococcus pluvialis for astaxanthin and lipid co-production: Advances and outlook

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