Microalgae as a future food source
Open accessAbstract
One of the key challenges that we face in the 21st century is the need to feed an ever-increasing human population with increasingly limited natural resources. Even today it is estimated that roughly 1 out of 9 people in the world are undernourished, of which the most important factor is protein-energy malnutrition. By establishing microalgae as a new food and feed platform, we have the opportunity to increase the supply of these essential products to address global demands in a more efficient and environmentally sustainable way. Many types of algae are nutritionally complete foods, their yields outperform most plant crops, and there is a growing set of tools to develop improved strains of algae. Similar improvements were achieved in traditional crops through thousands of years of breeding and strain selection, whereas with the newest genetic engineering tools and advanced strain selection techniques, similar changes can be implemented in microalgae in just a few years. Here we describe different strategies that could be used to enhance the nutritional content, productivity, and organoleptic traits of algae to help drive development of this new crop. Clearly developing more efficient, sustainable, and nutritious foods and feed would be an enormous benefit for the planet, and algae represents an opportunity to develop a new crop that would complement traditional agriculture, and one that could potential result in a more efficient means to meet the world's food and feed supply.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Direct extraction from wet biomass is a promising alternative.
“A promising alternative is direct extraction from wet biomass.”
From Microalgae biotechnology and its role in sustainable and healthy food design (2025) · cites this paper as Torres-Tiji et al., 2020
Figure 1 (section 1144) mentions optimizing downstream processing but does not describe extraction from wet biomass. Searches for “direct extraction,” “wet biomass,” and extraction without drying found no passage in our copy assessing that approach as a promising alternative. (LLM, conf=0.72)
Experimental — accuracy not yet measuredDirect extraction from wet biomass enables the use of aqueous-compatible techniques such as solution-based extraction and intensification technologies including ultrasound, electric fields, and alternative solvents.
“This approach enables the use of aqueous-compatible techniques—such as solution-based extraction—and intensification technologies, including ultrasound, electric fields, and alternative solvents (Torres-Tiji et al., 2020).”
From Microalgae biotechnology and its role in sustainable and healthy food design (2025) · cites this paper as Torres-Tiji et al., 2020
Figure 1 mentions optimizing downstream processing, but does not describe extraction from wet biomass or the techniques claimed. Searches for wet-biomass and solution-based extraction, ultrasound, electric fields, and solvents found no passage in our copy addressing those methods. (LLM, conf=0.76)
Experimental — accuracy not yet measuredArthrospira platensis, Auxenochlorella protothecoides, Dunaliella bardawil, Dunaliella salina, Schizochytrium sp., and Ulkenia sp. are GRAS.
“Other GRAS species are Arthrospira platensis, Auxenochlorella protothecoides, Dunaliella bardawil, Dunaliella salina, Schizochytrium sp., and Ulkenia sp. [194,208].”
From Microalgae n-3 PUFAs Production and Use in Food and Feed Industries (2021) · cites this paper as [208]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Brennan, L., & Owende, P. (2010) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2009.10.009 · Cited by 4,894 · see citing works
Commercial Applications of Microalgae
Spolaore, P., Joannis-Cassan, C., Duran, E., & Isambert, A. (2006) · Journal of Bioscience and Bioengineering · doi:10.1263/jbb.101.87 · Cited by 4,285 · see citing works
Liu, L., Johnson, H. L., Cousens, S., Perin, J., Scott, S., Lawn, J. E., Rudan, I., Campbell, H., Cibulskis, R., Li, M., et al. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60560-1 · Cited by 3,934 · see citing works
Where and why are 10 million children dying every year?
Black, R. E., Morris, S. S., & Bryce, J. (2003) · The Lancet · doi:10.1016/s0140-6736(03)13779-8 · Cited by 2,437 · see citing works
Micro-algae as a source of protein
Becker, E. W. (2007) · Biotechnology Advances · doi:10.1016/j.biotechadv.2006.11.002 · Cited by 2,311 · see citing works
Recovery of microalgal biomass and metabolites: Process options and economics
Molina Grima, E., Belarbi, E.-H., Acién Fernández, F. G., Robles Medina, A., & Chisti, Y. (2003) · Biotechnology Advances · doi:10.1016/s0734-9750(02)00050-2 · Cited by 2,286 · see citing works
Protein and amino acid requirements in human nutrition.
(2007) · PubMed · Cited by 2,227 · see citing works
Valuable Products from Biotechnology of Microalgae
Pulz, O., & Gross, W. (2004) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-004-1647-x · Cited by 2,132 · see citing works
Sheehan, J., Dunahay, T., Benemann, J., & Roessler, P. (1998) · doi:10.2172/15003040 · Cited by 1,753 · see citing works
Omega-3 fatty acids EPA and DHA: Health benefits throughout life
Swanson, D., Block, R., & Mousa, S. A. (2012) · Advances in Nutrition · doi:10.3945/an.111.000893 · Cited by 1,575 · see citing works
Algae as nutritional and functional food sources: revisiting our understanding.
Wells, M. L., Potin, P., Craigie, J. S., Raven, J. A., Merchant, S. S., Helliwell, K. E., Smith, A. G., Camire, M. E., & Brawley, S. H. (2017) · Journal of Applied Phycology · doi:10.1007/s10811-016-0974-5 · Cited by 1,562 · see citing works
Lipid productivity as a key characteristic for choosing algal species for biodiesel production
Griffiths, M. J., & Harrison, S. T. L. (2009) · Journal of Applied Phycology · doi:10.1007/s10811-008-9392-7 · Cited by 1,421 · see citing works
Commercial production of microalgae: ponds, tanks, tubes and Fermenters.
Borowitzka, M. A. (1999) · Journal of Biotechnology · doi:10.1016/s0168-1656(99)00083-8 · Cited by 1,317 · see citing works
Encapsulation in the food industry: a review
Kermasha, S. (1999) · International Journal of Food Sciences and Nutrition · doi:10.1080/096374899101256 · Cited by 1,202 · see citing works
Commercial potential for Haematococcus microalgae as a natural source of astaxanthin
Lorenz, R. T., & Cysewski, G. R. (2000) · Trends in biotechnology · doi:10.1016/s0167-7799(00)01433-5 · Cited by 1,190 · see citing works
Protein content and amino acid composition of commercially available plant-based protein isolates
Gorissen, S. H. M., Crombag, J. J. R., Senden, J. M. G., Waterval, W. A. H., Bierau, J., Verdijk, L. B., & van Loon, L. J. C. (2018) · Amino Acids · doi:10.1007/s00726-018-2640-5 · Cited by 1,169 · see citing works
A process model to estimate biodiesel production costs
Haas, M. J., McAloon, A. J., Yee, W., & Foglia, T. A. (2005) · Bioresource Technology · doi:10.1016/j.biortech.2005.03.039 · Cited by 1,157 · see citing works
Genetic Engineering of Algae for Enhanced Biofuel Production
Radakovits, R., Jinkerson, R. E., Darzins, A., & Posewitz, M. C. (2010) · Eukaryotic Cell · doi:10.1128/ec.00364-09 · Cited by 1,142 · see citing works
Fatty acid biosynthesis in microorganisms being used for Single Cell Oil production
Ratledge, C. (2004) · Biochimie · doi:10.1016/j.biochi.2004.09.017 · Cited by 1,125 · see citing works
Techno-Economic Analysis of Autotrophic Microalgae for Fuel Production
Davis, R., Aden, A., & Pienkos, P. T. (2011) · Applied Energy · doi:10.1016/j.apenergy.2011.04.018 · Cited by 1,069 · see citing works
Liang, Y., Sarkany, N., & Cui, Y. (2009) · Biotechnology Letters · doi:10.1007/s10529-009-9975-7 · Cited by 1,059 · see citing works
Handbook of Microalgal Culture: Applied Phycology and Biotechnology
(2013) · doi:10.1002/9781118567166 · Cited by 979 · see citing works
Nutritional and Health Benefits of Soy Proteins
Friedman, M., & Brandon, D. L. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0009246 · Cited by 919 · see citing works
Microalgal production — A close look at the economics
Norsker, N.-H., Barbosa, M. J., Vermuë, M. H., & Wijffels, R. H. (2011) · Biotechnology Advances · doi:10.1016/j.biotechadv.2010.08.005 · Cited by 819 · see citing works
Biofuels from algae: Challenges and potential
Hannon, M., Gimpel, J., Tran, M., Rasala, B., & Mayfield, S. (2010) · Biofuels · doi:10.4155/bfs.10.44 · Cited by 813 · see citing works
Self-citationAquatic phototrophs: efficient alternatives to land-based crops for biofuels
Dismukes, G. C., Carrieri, D., Bennette, N., Ananyev, G. M., & Posewitz, M. C. (2008) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2008.05.007 · Cited by 733 · see citing works
Carotenoids from microalgae: A review of recent developments
Gong, M., & Bassi, A. S. (2016) · Biotechnology Advances · doi:10.1016/j.biotechadv.2016.10.005 · Cited by 727 · see citing works
Monte Verde: Seaweed, Food, Medicine, and the Peopling of South America
Dillehay, T. D., Ramírez, C., Pino, M., Collins, M. B., Rossen, J., & Pino-Navarro, J. D. (2008) · Science · doi:10.1126/science.1156533 · Cited by 695 · see citing works
(2013) · doi:10.1007/978-94-007-5479-9 · Cited by 670 · see citing works
Microalgal biofactories: A promising approach towards sustainable omega-3 fatty acid production
Adarme-Vega, T. C., Lim, D. K. Y., Timmins, M., Vernen, F., Li, Y., & Schenk, P. M. (2012) · Microbial Cell Factories · doi:10.1186/1475-2859-11-96 · Cited by 641 · see citing works
Microalgae as versatile cellular factories for valued products
Koller, M., Muhr, A., & Braunegg, G. (2014) · Algal Research · doi:10.1016/j.algal.2014.09.002 · Cited by 639 · see citing works
Trends in Microalgae Incorporation Into Innovative Food Products With Potential Health Benefits
Caporgno, M. P., & Mathys, A. (2018) · Frontiers in Nutrition · doi:10.3389/fnut.2018.00058 · Cited by 639 · see citing works
Calkins, C. R., & Hodgen, J. M. (2007) · Meat Science · doi:10.1016/j.meatsci.2007.04.016 · Cited by 635 · see citing works
Miao, X., & Wu, Q. (2004) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2004.01.013 · Cited by 603 · see citing works
Stephenson, A. L., Kazamia, E., Dennis, J. S., Howe, C. J., Scott, S. A., & Smith, A. G. (2010) · Energy & Fuels · doi:10.1021/ef1003123 · Cited by 571 · see citing works
Beta Glucan: Health Benefits in Obesity and Metabolic Syndrome
Khoury, D. T. D. E., Cuda, C., Luhovyy, B. L., & Anderson, G. H. (2011) · Journal of Nutrition and Metabolism · doi:10.1155/2012/851362 · Cited by 548 · see citing works
Wang, Z. T., Ullrich, N., Joo, S., Waffenschmidt, S., & Goodenough, U. W. (2009) · Eukaryotic Cell · doi:10.1128/ec.00272-09 · Cited by 542 · see citing works
Microalgal mass culture systems and methods: their limitation and potential
Lee, Y.-K. (2001) · Journal of Applied Phycology · doi:10.1023/a:1017560006941 · Cited by 528 · see citing works
State of World Population 2017
Fund, U. N. P. (2017) · The state of world population/The State of world population · doi:10.18356/b19523c6-en · Cited by 513 · see citing works
Innovative natural functional ingredients from microalgae
Plaza, M., Herrero, M., Cifuentes, A., & Ibáñez, E. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf901070g · Cited by 509 · see citing works
High-Efficiency Transformation of Chlamydomonas reinhardtii by Electroporation
Shimogawara, K., Fujiwara, S., Grossman, A. R., & Usuda, H. (1998) · Genetics · doi:10.1093/genetics/148.4.1821 · Cited by 488 · see citing works
Flux balance analysis of primary metabolism in Chlamydomonas reinhardtii
Boyle, N. R., & Morgan, J. A. (2009) · BMC Systems Biology · doi:10.1186/1752-0509-3-4 · Cited by 455 · see citing works
van der Wel, H., & Loeve, K. (1972) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1972.tb02522.x · Cited by 443 · see citing works
Stable nuclear transformation of the diatomPhaeodactylum tricornutum
Apt, K. E., Grossman, A. R., & Kroth, P. G. (1996) · Molecular and General Genetics MGG · doi:10.1007/bf02172403 · Cited by 435 · see citing works
Food commodities from microalgae
Draaisma, R. B., Wijffels, R. H., (Ellen) Slegers, P., Brentner, L. B., Roy, A., & Barbosa, M. J. (2013) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2012.09.012 · Cited by 432 · see citing works
Vlasov, Y. G., Legin, A. V., Rudnitskaya, A. M., Natale, C. D., & D’Amico, A. (2005) · Pure and Applied Chemistry · doi:10.1351/pac200577111965 · Cited by 424 · see citing works
CRISPR/Cas9-induced knockout and knock-in mutations in Chlamydomonas reinhardtii
Shin, S.-E., Lim, J., Koh, H. G., Kim, E. K., Kang, N. K., Jeon, S., Kwon, S., Shin, W.-S., Lee, B., Hwangbo, K., et al. (2016) · Scientific Reports · doi:10.1038/srep27810 · Cited by 421 · see citing works
High-efficiency homologous recombination in the oil-producing alga Nannochloropsis sp.
Kilian, O., Benemann, C. S. E., Niyogi, K., & Vick, B. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1105861108 · Cited by 421 · see citing works
A CRISPR/Cas9 system adapted for gene editing in marine algae
Nymark, M., Sharma, A. K., Sparstad, T., Bones, A. M., & Winge, P. (2016) · Scientific Reports · doi:10.1038/srep24951 · Cited by 413 · see citing works
Ben‐Amotz, A., Katz, A., & Avron, M. (1982) · Journal of Phycology · doi:10.1111/j.1529-8817.1982.tb03219.x · Cited by 377 · see citing works
Metabolic engineering of algae for fourth generation biofuels production
Lu, J. J., Sheahan, C., & Fu, P. (2011) · Energy & Environmental Science · doi:10.1039/c0ee00593b · Cited by 371 · see citing works
Habib, M. A. B. (2008) · FAO eBooks · Cited by 368 · see citing works
Olaizola, M. (2000) · Journal of Applied Phycology · doi:10.1023/a:1008159127672 · Cited by 359 · see citing works
Work, V. H., Radakovits, R., Jinkerson, R. E., Meuser, J. E., Elliott, L. G., Vinyard, D. J., Laurens, L. M. L., Dismukes, G. C., & Posewitz, M. C. (2010) · Eukaryotic Cell · doi:10.1128/ec.00075-10 · Cited by 351 · see citing works
The Nature of Child Malnutrition and Its Long-Term Implications
Martorell, R. (1999) · Food and Nutrition Bulletin · doi:10.1177/156482659902000304 · Cited by 341 · see citing works
Natural genetic transformation: prevalence, mechanisms and function
Johnsborg, O., Eldholm, V., & Håvarstein, L. S. (2007) · Research in Microbiology · doi:10.1016/j.resmic.2007.09.004 · Cited by 338 · see citing works
Extremophilic micro-algae and their potential contribution in biotechnology
Varshney, P., Mikulic, P., Vonshak, A., Beardall, J., & Wangikar, P. P. (2014) · Bioresource Technology · doi:10.1016/j.biortech.2014.11.040 · Cited by 330 · see citing works
Genome editing of model oleaginous microalgae <i>Nannochloropsis</i> spp. by <scp>CRISPR</scp> /Cas9
Wang, Q., Lu, Y., Xin, Y., Wei, L., Huang, S., & Xu, J. (2016) · The Plant Journal · doi:10.1111/tpj.13307 · Cited by 312 · see citing works
Trophic Conversion of an Obligate Photoautotrophic Organism Through Metabolic Engineering
Zaslavskaia, L. A., Lippmeier, J. C., Shih, C., Ehrhardt, D., Grossman, A. R., & Apt, K. E. (2001) · Science · doi:10.1126/science.160015 · Cited by 307 · see citing works
Transformation of Nonselectable Reporter Genes in Marine Diatoms
Falciatore, A., Casotti, R., Leblanc, C., Abrescia, C., & Bowler, C. (1999) · Marine Biotechnology · doi:10.1007/pl00011773 · Cited by 300 · see citing works
Wakasugi, T., Nagai, T., Kapoor, M., Sugita, M., Ito, M. N., Ito, S., Tsudzuki, J., Nakashima, K., Tsudzuki, T., Suzuki, Y., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.11.5967 · Cited by 296 · see citing works
Belarbi, E. H., Molina, E., & Chisti, Y. (2000) · Enzyme and Microbial Technology · doi:10.1016/s0141-0229(99)00191-x · Cited by 281 · see citing works
Lönnerdal, B. (2014) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.071993 · Cited by 263 · see citing works
MOLECULAR GENETIC MANIPULATION OF THE DIATOM THALASSIOSIRA PSEUDONANA (BACILLARIOPHYCEAE)1
Poulsen, N., Chesley, P. M., & Kröger, N. (2006) · Journal of Phycology · doi:10.1111/j.1529-8817.2006.00269.x · Cited by 261 · see citing works
Comparative cost analysis of algal oil production for biofuels
Sun, A., Davis, R., Starbuck, M., Ben-Amotz, A., Pate, R., & Pienkos, P. T. (2011) · Energy · doi:10.1016/j.energy.2011.06.020 · Cited by 250 · see citing works
Glutamate: from discovery as a food flavor to role as a basic taste (umami)
Kurihara, K. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.27462d · Cited by 246 · see citing works
Electronic Tongue—A Tool for All Tastes?
Podrażka, M., Bączyńska, E., Kundys, M., Jeleń, P. S., & Nery, E. W. (2017) · Biosensors · doi:10.3390/bios8010003 · Cited by 242 · see citing works
Brazzein, a new high‐potency thermostable sweet protein from Pentadiplandra brazzeana B
Ming, D., & Hellekant, G. (1994) · FEBS Letters · doi:10.1016/0014-5793(94)01184-2 · Cited by 238 · see citing works
Multichannel taste sensor using lipid membranes
Hayashi, K., Yamanaka, M., Toko, K., & Yamafuji, K. (1990) · Sensors and Actuators B Chemical · doi:10.1016/0925-4005(90)85006-k · Cited by 231 · see citing works
Steinbrenner, J., & Sandmann, G. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.01461-06 · Cited by 226 · see citing works
Chae, S.-R., Hwang, E.-J., & Shin, H. (2005) · Bioresource Technology · doi:10.1016/j.biortech.2005.02.037 · Cited by 223 · see citing works
MICROALGAE AND CYANOBACTERIA: FOOD FOR THOUGHT1
Gantar, M., & Svirčev, Z. B. (2008) · Journal of Phycology · doi:10.1111/j.1529-8817.2008.00469.x · Cited by 223 · see citing works
Guccione, A., Biondi, N., Sampietro, G., Rodolfi, L., Bassi, N., & Tredici, M. R. (2014) · Biotechnology for Biofuels · doi:10.1186/1754-6834-7-84 · Cited by 217 · see citing works
Purification of monellin, the sweet principle of Dioscoreophyllum cumminsii
Morris, J. A., & Cagan, R. H. (1972) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/0304-4165(72)90320-0 · Cited by 207 · see citing works
Chlamydomonas reinhardtii chloroplasts as protein factories
Mayfield, S. P., Manuell, A. L., Chen, S., Wu, J., Tran, M., Siefker, D., Muto, M., & Marin-Navarro, J. (2007) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2007.02.001 · Cited by 201 · see citing works
Self-citationPotential of sponges and microalgae for marine biotechnology
Wijffels, R. H. (2008) · Trends in biotechnology · doi:10.1016/j.tibtech.2007.10.002 · Cited by 201 · see citing works
Biotechnological production of limonene in microorganisms
Jongedijk, E., Cankar, K., Buchhaupt, M., Schrader, J., Bouwmeester, H. J., & Beekwilder, J. (2016) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-016-7337-7 · Cited by 200 · see citing works
Hejazi, M. A., & Wijffels, R. H. (2004) · Trends in biotechnology · doi:10.1016/j.tibtech.2004.02.009 · Cited by 196 · see citing works
Development of a GFP reporter gene for Chlamydomonas reinhardtii chloroplast
Franklin, S. E., Ngo, B. X., Efuet, E. T., & Mayfield, S. P. (2002) · The Plant Journal · doi:10.1046/j.1365-313x.2002.01319.x · Cited by 194 · see citing works
Self-citationCordero, B. F., Couso, I., León, R., Rodrı́guez, H., & Vargas, M. A. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-011-3262-y · Cited by 190 · see citing works
Production of unique immunotoxin cancer therapeutics in algal chloroplasts
Tran, M., Van, C., Barrera, D. J., Pettersson, P. L., Peinado, C. D., Bui, J. D., & Mayfield, S. P. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1214638110 · Cited by 186 · see citing works
Self-citationJoy, J. M., Lowery, R. P., Wilson, J. M., Purpura, M., De Souza, E. O., Wilson, S. M., Kalman, D. S., Dudeck, J. E., & Jäger, R. (2013) · Nutrition Journal · doi:10.1186/1475-2891-12-86 · Cited by 179 · see citing works
Industrial‐strength ecology: trade‐offs and opportunities in algal biofuel production
Shurin, J. B., Abbott, R. L., Deal, M. S., Kwan, G. T., Litchman, E., McBride, R. C., Mandal, S., & Smith, V. H. (2013) · Ecology Letters · doi:10.1111/ele.12176 · Cited by 176 · see citing works
Chlamydomonas reinhardtii Genome Project. A Guide to the Generation and Use of the cDNA Information
Shrager, J., Hauser, C. R., Chang, C.-W., Harris, E. H., Davies, J. P., McDermott, J., Kuehn, R., Zhang, Z., & Grossman, A. R. (2003) · PLANT PHYSIOLOGY · doi:10.1104/pp.016899 · Cited by 173 · see citing works
Sweet proteins – Potential replacement for artificial low calorie sweeteners
Kant, R. (2005) · Nutrition Journal · doi:10.1186/1475-2891-4-5 · Cited by 172 · see citing works
Brown, M. R., & Jeffrey, S. W. (1992) · Journal of Experimental Marine Biology and Ecology · doi:10.1016/0022-0981(92)90192-d · Cited by 172 · see citing works
Borowitzka, M. A., & Moheimani, N. R. (2013) · Algae for Biofuels and Energy · doi:10.1007/978-94-007-5479-9_8 · Cited by 167 · see citing works
An integrated optofluidic platform for Raman-activated cell sorting
Lau, A. Y., Lee, L. P., & Chan, J. W. (2008) · Lab on a Chip · doi:10.1039/b803598a · Cited by 165 · see citing works
Vitamin content of four marine microalgae. Potential use as source of vitamins in nutrition
Fábregas, J., & Herrero, C. (1990) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/bf01569683 · Cited by 162 · see citing works
Advances in genetic engineering of marine algae
Qin, S., Lin, H., & Jiang, P. (2012) · Biotechnology Advances · doi:10.1016/j.biotechadv.2012.05.004 · Cited by 162 · see citing works
Iwamoto, H. (2003) · doi:10.1002/9780470995280.ch11 · Cited by 157 · see citing works
Barsanti, L. A., Vismara, R., Passarelli, V., & Gualtieri, P. (2001) · Journal of Applied Phycology · doi:10.1023/a:1008105416065 · Cited by 156 · see citing works
Analysis of the self-shading effect on algal vertical distribution in natural waters
Shigesada, N., & Ōkubo, A. (1981) · Journal of Mathematical Biology · doi:10.1007/bf00276919 · Cited by 156 · see citing works
Raman-Activated Cell Sorting Based on Dielectrophoretic Single-Cell Trap and Release
Zhang, P., Ren, L., Zhang, X., Shan, Y., Wang, Y., Ji, Y., Yin, H., Huang, W. E., Xu, J., & Ma, B. (2015) · Analytical Chemistry · doi:10.1021/ac503974e · Cited by 154 · see citing works
Robust expression of a bioactive mammalian protein in <i>Chlamydomonas</i> chloroplast
Manuell, A. L., Beligni, M. V., Elder, J. H., Siefker, D. T., Tran, M., Weber, A., McDonald, T. L., & Mayfield, S. P. (2007) · Plant Biotechnology Journal · doi:10.1111/j.1467-7652.2007.00249.x · Cited by 154 · see citing works
Self-citationChemical Composition of Spirulina platensis Cultivated in Uzbekistan
Babadzhanov, A. S., Abdusamatova, N., Yusupova, F. M., Faizullaeva, N. S., Mezhlumyan, L. G., & Маликова, М. Х. (2004) · Chemistry of Natural Compounds · doi:10.1023/b:conc.0000039141.98247.e8 · Cited by 143 · see citing works
Arterburn, L. M., Oken, H. A., Hoffman, J. P., Bailey‐Hall, E., Chung, G., Rom, D., Hamersley, J., & McCarthy, D. (2007) · Lipids · doi:10.1007/s11745-007-3098-5 · Cited by 135 · see citing works
Commercial production of microalgae: ponds, tanks, and fermenters
Borowitzka, M. A. (1999) · Progress in industrial microbiology · doi:10.1016/s0079-6352(99)80123-4 · Cited by 129 · see citing works
Enhanced Genetic Tools for Engineering Multigene Traits into Green Algae
Rasala, B. A., Chao, S.-S., Pier, M. M., Barrera, D. J., & Mayfield, S. P. (2014) · PLoS ONE · doi:10.1371/journal.pone.0094028 · Cited by 126 · see citing works
Self-citationNi, J., Tao, F., Du, H., & Xu, P. (2015) · Scientific Reports · doi:10.1038/srep13670 · Cited by 109 · see citing works
Song, Y., Yin, H., & Huang, W. E. (2016) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2016.04.002 · Cited by 108 · see citing works
Acquired flavor acceptance and intake facilitated by monosodium glutamate in humans
Yeomans, M. R., Gould, N. J., Mobini, S., & Prescott, J. (2007) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.12.009 · Cited by 107 · see citing works
Effects of the microalgae Chlamydomonas on gastrointestinal health
Fields, F. J., Lejzerowicz, F., Schroeder, D., Ngoi, S. M., Tran, M., McDonald, D., Jiang, L., Chang, J. T., Knight, R., & Mayfield, S. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2019.103738 · Cited by 104 · see citing works
Self-citationElectrotransformation of Chlorella vulgaris
Chow, K.-C., & Tung, W. L. (1999) · Plant Cell Reports · doi:10.1007/s002990050660 · Cited by 103 · see citing works
Evaluation of a taste sensor instrument (electronic tongue) for use in formulation development
Lorenz, J. K., Reo, J., Hendl, O., Worthington, J. H., & Petrossian, V. D. (2008) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2008.09.042 · Cited by 98 · see citing works
Terashima, M., Freeman, E. S., Jinkerson, R. E., & Jonikas, M. C. (2014) · The Plant Journal · doi:10.1111/tpj.12682 · Cited by 97 · see citing works
Doetsch, N., Favreau, M. R., Kuscuoglu, N., Thompson, M. D., & Hallick, R. B. (2001) · Current Genetics · doi:10.1007/s002940000174 · Cited by 97 · see citing works
Genetic and metabolic engineering in diatoms
Huang, W., & Daboussi, F. (2017) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2016.0411 · Cited by 97 · see citing works
Wang, C., Chin, C., Ho, C., Hwang, C., Polashock, J. J., & Martin, C. E. (1996) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf960174t · Cited by 96 · see citing works
Yang, B., Liu, J., Jiang, Y., & Chen, F. (2016) · Biotechnology Journal · doi:10.1002/biot.201500617 · Cited by 94 · see citing works
Turner, N. J. (2003) · Canadian Journal of Botany · doi:10.1139/b03-029 · Cited by 93 · see citing works
Scranton, M. A., Ostrand, J. T., Georgianna, D. R., Lofgren, S., Li, D. D., Ellis, R. C., Carruthers, D. N., Dräger, A., Masica, D. L., & Mayfield, S. P. (2016) · Algal Research · doi:10.1016/j.algal.2016.02.011 · Cited by 93 · see citing works
Self-citationTetali, S. D., Mitra, M., & Melis, A. (2006) · Planta · doi:10.1007/s00425-006-0392-z · Cited by 88 · see citing works
Systems metabolic engineering strategies for the production of amino acids
Ma, Q., Zhang, Q., Xu, Q., Zhang, C., Li, Y., Fan, X., Xie, X., & Chen, N. (2017) · Synthetic and Systems Biotechnology · doi:10.1016/j.synbio.2017.07.003 · Cited by 87 · see citing works
Establishment ofAgrobacterium tumefaciens-mediated genetic transformation inDunaliella bardawil
Anila, N., Chandrashekar, A., Ravishankar, G. A., & Sarada, R. (2011) · European Journal of Phycology · doi:10.1080/09670262.2010.550386 · Cited by 81 · see citing works
Beacham, T. A., Macia, V. M., Rooks, P., White, D. A., & Ali, S. T. (2015) · Biotechnology Reports · doi:10.1016/j.btre.2015.05.007 · Cited by 80 · see citing works
Fallah, A. A., Sarmast, E., Saied, H. D., Engardeh, J., Mahmoodnia, L., Khaledifar, A., & Jafari, T. (2017) · Clinical Nutrition · doi:10.1016/j.clnu.2017.09.019 · Cited by 80 · see citing works
Towards high-throughput microfluidic Raman-activated cell sorting
Zhang, Q., Zhang, P., Gou, H., Mou, C., Huang, W. E., Yang, M., Xu, J., & Ma, B. (2015) · The Analyst · doi:10.1039/c5an01074h · Cited by 77 · see citing works
Loera-Quezada, M. M., Leyva‐González, M. A., Velázquez‐Juárez, G., Sánchez-Calderón, L., Nascimento, M. D., López-Arredondo, D. L., & Herrera‐Estrella, L. (2016) · Plant Biotechnology Journal · doi:10.1111/pbi.12564 · Cited by 77 · see citing works
Human serum amyloid A3 peptide enhances intestinal MUC3 expression and inhibits EPEC adherence
Larson, M. A., Wei, S. H., Weber, A. M., Mack, D. R., & McDonald, T. L. (2003) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)02901-7 · Cited by 73 · see citing works
Fed-batch mixotrophic cultivation of Chlamydomonas reinhardtii for high-density cultures
Fields, F. J., Ostrand, J. T., & Mayfield, S. P. (2018) · Algal Research · doi:10.1016/j.algal.2018.05.006 · Cited by 66 · see citing works
Self-citationMolino, J. V. D., de Carvalho, J. C. M., & Mayfield, S. P. (2018) · PLoS ONE · doi:10.1371/journal.pone.0192433 · Cited by 61 · see citing works
Self-citationStable nuclear transformation of the diatom Chaetoceros sp.
Miyagawa‐Yamaguchi, A., Okami, T., Kira, N., Yamaguchi, H., Ohnishi, K., & Adachi, M. (2011) · Phycological Research · doi:10.1111/j.1440-1835.2011.00607.x · Cited by 58 · see citing works
Feng, X., Walker, T., Bridges, W. C., Thornton, C. D., & Gopalakrishnan, K. (2014) · Bioresource Technology · doi:10.1016/j.biortech.2014.03.120 · Cited by 58 · see citing works
Insertion mutagenesis of Chlamydomonas reinhardtii by electroporation and heterologous DNA.
Tang, D. K. H., Qiao, S. Y., & Wu, M. (1995) · PubMed · Cited by 54 · see citing works
Cheng, K., Ren, M., & Ogden, K. L. (2012) · Bioresource Technology · doi:10.1016/j.biortech.2012.09.085 · Cited by 54 · see citing works
Safety evaluation of Whole Algalin Protein (WAP) from Chlorella protothecoides
Szabo, N. J., Matulka, R. A., & Chan, T. (2013) · Food and Chemical Toxicology · doi:10.1016/j.fct.2013.05.035 · Cited by 52 · see citing works
Biological roles of milk osteopontin
Jiang, R., & Lönnerdal, B. L. (2016) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000275 · Cited by 49 · see citing works
High‐value Recombinant Protein Production in Microalgae
Barrera, D. J., & Mayfield, S. P. (2013) · doi:10.1002/9781118567166.ch27 · Cited by 48 · see citing works
Self-citationKawata, Y., Yano, S., Kojima, H., & Toyomizu, M. (2004) · Marine Biotechnology · doi:10.1007/s10126-003-0037-1 · Cited by 48 · see citing works
Kanaga, K., Pandey, A., Kumar, S., & Geetanjali, G. (2015) · Bioresource Technology · doi:10.1016/j.biortech.2015.11.017 · Cited by 44 · see citing works
Matsuda, F., Hayashi, M., & Kondo, A. (2011) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.110482 · Cited by 41 · see citing works
The Selective Breeding of the Freshwater Microalga Chlamydomonas reinhardtii for Growth in Salinity
Takouridis, S. J., Tribe, D. E., Gras, S. L., & Martin, G. J. O. (2015) · Bioresource Technology · doi:10.1016/j.biortech.2014.10.120 · Cited by 40 · see citing works
Dunaliella salina as a novel host for the production of recombinant proteins
Feng, S., Li, X., Xu, Z., & Qi, J. (2014) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-014-5636-4 · Cited by 38 · see citing works
A role for algae as human food in antiquity
Aaronson, S. (1986) · Food and Foodways · doi:10.1080/07409710.1986.9961891 · Cited by 33 · see citing works
Fields, F. J., Ostrand, J. T., Tran, M., & Mayfield, S. P. (2019) · Algal Research · doi:10.1016/j.algal.2019.101523 · Cited by 33 · see citing works
Self-citationThe European Food Safety Authority
Silano, M., & Silano, V. (2020) · CRC Press eBooks · doi:10.1201/9781003088493-11 · Cited by 29 · see citing works
Jia, Y., Li, S., Allen, G. C., Feng, S., & Xue, L. (2012) · Current Microbiology · doi:10.1007/s00284-012-0102-y · Cited by 20 · see citing works
Anderson, M. S., Muff, T. J., Georgianna, D. R., & Mayfield, S. P. (2016) · Algal Research · doi:10.1016/j.algal.2016.12.002 · Cited by 20 · see citing works
Self-citationPromoter Trapping in Microalgae Using the Antibiotic Paromomycin as Selective Agent
Vilà, M., Díaz‐Santos, E., de la Vega, M., Rodrı́guez, H., Vargas, Á., & León, R. (2012) · Marine Drugs · doi:10.3390/md10122749 · Cited by 18 · see citing works
Şapcı, Z., & Morken, J. (2014) · Energy Conversion and Management · doi:10.1016/j.enconman.2013.12.010 · Cited by 18 · see citing works
Intestinal Absorption of IgA in the Newborn
Vukavić, T. (1983) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-198302020-00006 · Cited by 18 · see citing works
Carcelén, J. N., Marchante-Gayón, J. M., Rodríguez‐González, P., Valledor, L., Cañal, M. J., & Alonso, J. I. G. (2017) · Microbial Cell Factories · doi:10.1186/s12934-017-0759-9 · Cited by 14 · see citing works
(2006) · Chemistry International · doi:10.1515/ci.2006.28.2.32 · Cited by 9 · see citing works
Intestinal Absorption of IgA in the Newborn
Vukavić, T. (1983) · Journal of Pediatric Gastroenterology and Nutrition · doi:10.1097/00005176-198305000-00006 · Cited by 5 · see citing works
Fecal Streptococcus as an indicator in disinfected water and waste water
Kott, Y. (1983) · Antonie van Leeuwenhoek · doi:10.1007/bf00399553 · Cited by 4 · see citing works
Binnal, P., & Babu, P. N. (2017) · Biofuels · doi:10.1080/17597269.2017.1336351 · Cited by 2 · see citing works
(1994) · Industrial chemistry library · doi:10.1016/b978-0-444-88887-7.50010-6 · Cited by 2 · see citing works
Flagged first, then by citations
4 of the 152 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
The Potential Impact of Probiotics on Human Health: An Update on Their Health-Promoting Properties
Maftei, N.-M., Raileanu, C. R., Balta, A. A., Ambrose, L., Boev, M., Marin, D. B., & Lisa, E. L. (2024) · Microorganisms · doi:10.3390/microorganisms12020234 · Cited by 381 · see citing works
Algal proteins: Production strategies and nutritional and functional properties
Geada, P., Moreira, C., Silva, M., Nunes, R., Madureira, L., Rocha, C. M. R., Pereira, R. N., Vicente, A. A., & Teixeira, J. A. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.125125 · Cited by 290 · see citing works
Role of Microalgae in Achieving Sustainable Development Goals and Circular Economy
Olabi, A. G., Shehata, N., Sayed, E. T., Rodriguez, C., Anyanwu, R. C., Russell, C., & Abdelkareem, M. A. (2023) · Science of The Total Environment · doi:10.1016/j.scitotenv.2022.158689 · Cited by 273 · see citing works
Zhang, D., Zhong, D., Ouyang, J., He, J., Qi, Y., Chen, W., Zhang, X., Tao, W., & Zhou, M. (2022) · Nature Communications · doi:10.1038/s41467-022-28744-4 · Cited by 257 · see citing works
Algae as Food in Europe: An Overview of Species Diversity and Their Application
Mendes, M., Navalho, S., Ferreira, A., Paulino, C., Figueiredo, D., Silva, D., Gao, F., Gama, F., Bombo, G., Jacinto, R., et al. (2022) · Foods · doi:10.3390/foods11131871 · Cited by 234 · see citing works
Recent advancements in the genetic engineering of microalgae
Sproles, A. E., Fields, F. J., Smalley, T. N., Le, C. H., Badary, A., & Mayfield, S. P. (2021) · Algal Research · doi:10.1016/j.algal.2020.102158 · Cited by 228 · see citing works
Self-citationChallenging microalgal vitamins for human health
Del Mondo, A., Smerilli, A., Sané, E., Sansone, C., & Brunet, C. (2020) · Microbial Cell Factories · doi:10.1186/s12934-020-01459-1 · Cited by 220 · see citing works
Microalgae n-3 PUFAs Production and Use in Food and Feed Industries
Remize, M., Brunel, Y., Silva, J. L., Berthon, J.-Y., & Filaire, E. (2021) · Marine Drugs · doi:10.3390/md19020113 · Cited by 214 · see citing works
Nagarajan, D., Varjani, S., Lee, D., & Chang, J. (2021) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2021.111549 · Cited by 206 · see citing works
A hybrid inorganic–biological artificial photosynthesis system for energy-efficient food production
Hann, E. C., Overa, S., Harland‐Dunaway, M., Narvaez, A. F., Le, D. N., Orozco-Cárdenas, M. L., Jiao, F., & Jinkerson, R. E. (2022) · Nature Food · doi:10.1038/s43016-022-00530-x · Cited by 202 · see citing works
Developing algae as a sustainable food source
Diaz, C. J., Douglas, K. J., Kang, K., Kolarik, A. L., Malinovski, R., Torres-Tiji, Y., Molino, J. V., Badary, A., & Mayfield, S. P. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2022.1029841 · Cited by 194 · see citing works
Self-citationCarotenoid Production from Microalgae: Biosynthesis, Salinity Responses and Novel Biotechnologies
Ren, Y., Sun, H., Deng, J., Huang, J., & Chen, F. (2021) · Marine Drugs · doi:10.3390/md19120713 · Cited by 193 · see citing works
Arif, M., Li, Y., El-Dalatony, M. M., Zhang, C., Li, X., & Salama, E. (2020) · Renewable Energy · doi:10.1016/j.renene.2020.10.066 · Cited by 182 · see citing works
Digestibility, bioaccessibility and bioactivity of compounds from algae
Demarco, M., de Moraes, J. O., Matos, Â. P., Dérner, R. B., Neves, F. D. F., & Tribuzi, G. (2022) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2022.02.004 · Cited by 181 · see citing works
Empowering blue economy: From underrated ecosystem to sustainable industry
Choudhary, P., Subhash, G. V., Khade, M., Savant, S., Musale, A. S., Raja Krishna Kumar, G., Chelliah, M. S., & Dasgupta, S. (2021) · Journal of Environmental Management · doi:10.1016/j.jenvman.2021.112697 · Cited by 169 · see citing works
Microalgae-Based Biodiesel Production and Its Challenges and Future Opportunities: A Review
Gaurav, K., Neeti, K., & Singh, R. (2024) · Green Technologies and Sustainability · doi:10.1016/j.grets.2023.100060 · Cited by 165 · see citing works
Chen, L., Giesy, J. P., Adamovský, O., Svirčev, Z. B., Meriluoto, J. A. O., Codd, G. A., Mijović, B., Shi, T., Tuo, X., Li, S.-C., et al. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.142319 · Cited by 165 · see citing works
Ren, Y., Deng, J., Huang, J., Wu, Z., Yi, L., Bi, Y., & Chen, F. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.125736 · Cited by 155 · see citing works
Trovão, M., Schüler, L., Machado, A., Bombo, G., Navalho, S., Barros, A. I. R. N. A., Pereira, H., Silva, J., Freitas, F., & Varela, J. C. S. (2022) · Marine Drugs · doi:10.3390/md20070440 · Cited by 160 · see citing works
Bioproducts from microalgae biomass: Technology, sustainability, challenges and opportunities
Calijuri, M. L., Silva, T. A., Magalhães, I. B., Pereira, A. S. A. D. P., Marangon, B. B., de Assis, L. R., & Lorentz, J. F. (2022) · Chemosphere · doi:10.1016/j.chemosphere.2022.135508 · Cited by 149 · see citing works
Alternative Protein Sources and Novel Foods: Benefits, Food Applications and Safety Issues
Quintieri, L., Nitride, C., Angelis, E. D., Lamonaca, A., Pilolli, R., Russo, F., & Monaci, L. (2023) · Nutrients · doi:10.3390/nu15061509 · Cited by 155 · see citing works
Microalgae‐Based Hydrogel for Inflammatory Bowel Disease and Its Associated Anxiety and Depression
Zhong, D., Jin, K., Wang, R., Chen, B., Zhang, J., Ren, C., Chen, X. S., Lu, J., & Zhou, M. (2024) · Advanced Materials · doi:10.1002/adma.202312275 · Cited by 148 · see citing works
Vegan probiotic products: A modern tendency or the newest challenge in functional foods
Pimentel, T. C., da Costa, W. K. A., Barão, C. E., Rosset, M., & Magnani, M. (2020) · Food Research International · doi:10.1016/j.foodres.2020.110033 · Cited by 143 · see citing works
Microalgae proteins as sustainable ingredients in novel foods: recent developments and challenges
Mosibo, O. K., Ferrentino, G., & Udenigwe, C. C. (2024) · Foods · doi:10.3390/foods13050733 · Cited by 140 · see citing works
Artificial Intelligence and/or Machine Learning Algorithms in Microalgae Bioprocesses
Imamoglu, E. (2024) · Bioengineering · doi:10.3390/bioengineering11111143 · Cited by 143 · see citing works
Oral drug delivery platforms for biomedical applications
Ouyang, J., Zhang, Z., Deng, B., Liu, J., Wang, L., Liu, H., Koo, S., Chen, S., Li, Y., Yaremenko, A. V., et al. (2023) · Materials Today · doi:10.1016/j.mattod.2023.01.002 · Cited by 136 · see citing works
Barros de Medeiros, V. P., da Costa, W. K. A., da Silva, R. T., Pimentel, T. C., & Magnani, M. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1879729 · Cited by 134 · see citing works
Su, M., Bastiaens, L., Verspreet, J., & Hayes, M. (2023) · Foods · doi:10.3390/foods12203878 · Cited by 129 · see citing works
Michel, F., Knaapila, A., Hartmann, C., & Siegrist, M. (2021) · Food Quality and Preference · doi:10.1016/j.foodqual.2021.104195 · Cited by 127 · see citing works
Protein Sources Alternative to Meat: State of the Art and Involvement of Fermentation
Molfetta, M., de Morais, E. G., Barreira, L. A., Bruno, G. L., Porcelli, F., Dugat‐Bony, É., Bonnarme, P., & Minervini, F. (2022) · Foods · doi:10.3390/foods11142065 · Cited by 133 · see citing works
Thanigaivel, S., Priya, A. K., Dutta, K., Rajendran, S., & Vasseghian, Y. (2022) · Fuel · doi:10.1016/j.fuel.2021.122827 · Cited by 126 · see citing works
Spirulina platensis Protein as Sustainable Ingredient for Nutritional Food Products Development
Ramírez-Rodrigues, M. M., Estrada-Beristain, C., Metri-Ojeda, J., Pérez-Alva, A., & Baigts-Allende, D. K. (2021) · Sustainability · doi:10.3390/su13126849 · Cited by 125 · see citing works
Microalgal Cell Biofactory—Therapeutic, Nutraceutical and Functional Food Applications
Kiran, B. R., & Venkata Mohan, S. (2021) · Plants · doi:10.3390/plants10050836 · Cited by 124 · see citing works
Microalgae: potential novel protein for sustainable human nutrition
Williamson, E., Ross, I. L., Wall, B. T., & Hankamer, B. D. (2023) · Trends in Plant Science · doi:10.1016/j.tplants.2023.08.006 · Cited by 120 · see citing works
Thoré, E. S. J., Muylaert, K., Bertram, M. G., & Brodin, T. (2023) · Current Biology · doi:10.1016/j.cub.2022.12.032 · Cited by 113 · see citing works
Algae as a potential source of protein meat alternatives
Espinosa‐Ramírez, J., Mondragón, A. D. C., Rodríguez, J. A., Lorenzo, J. M., & Santos, E. M. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1254300 · Cited by 119 · see citing works
Isolation, structures and biological activities of polysaccharides from Chlorella: a review
Yuan, Q., Li, H., Wei, Z., Lv, K., Gao, C., Liu, Y., & Zhao, L. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.09.080 · Cited by 104 · see citing works
Sutherland, D. L., McCauley, J. I., Labeeuw, L., Ray, P., Kuzhiumparambil, U., Hall, C., Doblin, M. A., Nguyen, L. N., & Ralph, P. J. (2021) · Current Research in Environmental Sustainability · doi:10.1016/j.crsust.2021.100050 · Cited by 103 · see citing works
Gouda, M., Tadda, M. A., Zhao, Y., Farmanullah, F., Chu, B., Li, X., & He, Y. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.806692 · Cited by 105 · see citing works
Machado, L. F., Carvalho, G., & Pereira, R. N. (2022) · Biomass · doi:10.3390/biomass2020006 · Cited by 100 · see citing works
Key Challenges for the Commercial Expansion of Ingredients from Algae into Human Food Products
Hosseinkhani, N., McCauley, J. I., & Ralph, P. J. (2022) · Algal Research · doi:10.1016/j.algal.2022.102696 · Cited by 98 · see citing works
Chlamydomonas reinhardtii: A Factory of Nutraceutical and Food Supplements for Human Health
Masi, A., Leonelli, F., Scognamiglio, V., Gasperuzzo, G., Antonacci, A., & Terzidis, M. A. (2023) · Molecules · doi:10.3390/molecules28031185 · Cited by 96 · see citing works
Environmental impacts on commercial microalgae-based products: Sustainability metrics and indicators
Deprá, M. C., Severo, I. A., dos Santos, A. M., Zepka, L. Q., & Lopes, E. J. (2020) · Algal Research · doi:10.1016/j.algal.2020.102056 · Cited by 95 · see citing works
Microbial applications for sustainable space exploration beyond low Earth orbit
Koehle, A. P., Brumwell, S. L., Seto, E. P., Lynch, A. M., & Urbaniak, C. (2023) · npj Microgravity · doi:10.1038/s41526-023-00285-0 · Cited by 101 · see citing works
Bioremediation of phenolic pollutants by algae - current status and challenges
Wu, P., Zhang, Z., Luo, Y., Bai, Y., & Fan, J. (2022) · Bioresource Technology · doi:10.1016/j.biortech.2022.126930 · Cited by 95 · see citing works
Gohara-Beirigo, A. K., Matsudo, M. C., Cezare-Gomes, E. A., de Carvalho, J. C. M., & Danesi, E. D. G. (2022) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2022.04.030 · Cited by 97 · see citing works
Recent advancements in mixotrophic bioprocessing for production of high value microalgal products
Patel, A. K., Singhania, R. R., Sim, S. J., & Dong, C. (2020) · Bioresource Technology · doi:10.1016/j.biortech.2020.124421 · Cited by 91 · see citing works
Liu, F., Li, M., Wang, Q., Yan, J., Han, S., Ma, C., Ma, P., Liu, X., & McClements, D. J. (2022) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2033683 · Cited by 93 · see citing works
Podgórska-Kryszczuk, I. (2024) · Molecules · doi:10.3390/molecules29225387 · Cited by 88 · see citing works
Innovative and Healthier Dairy Products through the Addition of Microalgae: A Review
Hernández, H., Nunes, M. C., Prista, C., & Raymundo, A. (2022) · Foods · doi:10.3390/foods11050755 · Cited by 91 · see citing works
Oral Microalgae-Nano Integrated System against Radiation-Induced Injury
Zhang, D., He, J., Cui, J., Wang, R., Tang, Z., Yu, H., & Zhou, M. (2023) · ACS Nano · doi:10.1021/acsnano.3c01502 · Cited by 88 · see citing works
Karabulut, G., Purkiewicz, A., & Goksen, G. (2024) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.13372 · Cited by 85 · see citing works
Waste-to-nutrition: a review of current and emerging conversion pathways
Javourez, U., O’Donohue, M. J., & Hamelin, L. (2021) · Biotechnology Advances · doi:10.1016/j.biotechadv.2021.107857 · Cited by 85 · see citing works
General approaches to biopolymer-based Pickering emulsions
Rayees, R., Gani, A., Noor, N., Ayoub, A., & Ashraf, Z. U. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.131430 · Cited by 83 · see citing works
Yu, B. S., Pyo, S., Lee, J., & Han, K. (2024) · Microbial Cell Factories · doi:10.1186/s12934-024-02588-7 · Cited by 95 · see citing works
Cheng, P., Zhou, C., Chu, R., Chang, T., Xu, J., Ruan, R. R., Chen, P. L., & Yan, X. (2020) · Algal Research · doi:10.1016/j.algal.2020.102076 · Cited by 80 · see citing works
Advances of Amifostine in Radiation Protection: Administration and Delivery
Ji, L., Cui, P., Zhou, S., Qiu, L., Huang, H. H., Wang, C., & Wang, J. (2023) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.3c00600 · Cited by 82 · see citing works
Yin, Z., Chu, R., Zhu, L., Li, S., Mo, F., Hu, D., & Liu, C. (2021) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2021.111159 · Cited by 81 · see citing works
Fermentation of microalgal biomass for innovative food production
Garofalo, C., Norici, A., Mollo, L., Osimani, A., & Aquilanti, L. (2022) · Microorganisms · doi:10.3390/microorganisms10102069 · Cited by 80 · see citing works
Potential applications of algae in biochemical and bioenergy sector
Arora, K., Kumar, P., Bose, D., Li, X., & Kulshrestha, S. (2021) · 3 Biotech · doi:10.1007/s13205-021-02825-5 · Cited by 86 · see citing works
Ahmed, N., Sheikh, M. A., Ubaid, M., Chauhan, P., Kumar, K., & Choudhary, S. (2024) · Measurement Food · doi:10.1016/j.meafoo.2024.100163 · Cited by 84 · see citing works
Challenges in Functional Food Products with the Incorporation of Some Microalgae
Çelekli, A., Özbal, B., & Bozkurt, H. (2024) · Foods · doi:10.3390/foods13050725 · Cited by 80 · see citing works
Patel, A. K., Singhania, R. R., Dong, C., Obulisami, P. K., & Sim, S. J. (2021) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2021.111669 · Cited by 78 · see citing works
Priorities for ocean microbiome research
Abreu, A., Bourgois, E., Gristwood, A., Troublé, R., Oceans, T., Acinas, S. G., Peer Bork, B., Boss, E., Bowler, C., Budinich, M., et al. (2022) · Nature Microbiology · doi:10.1038/s41564-022-01145-5 · Cited by 76 · see citing works
Insight on Current Advances in Food Science and Technology for Feeding the World Population
Valoppi, F., Agustin, M. B., Abik, F., de Carvalho, D. M., Sithole, J., Bhattarai, M., Varis, J. J., Arzami, A. N., Pulkkinen, E., & Mikkonen, K. S. (2021) · Frontiers in Sustainable Food Systems · doi:10.3389/fsufs.2021.626227 · Cited by 75 · see citing works
Landscape of microalgae omics and metabolic engineering research for strain improvement: An overview
Stavridou, E., Karapetsi, L., Nteve, G., Tsintzou, G. P., Chatzikonstantinou, M., Tsaousi, M., Martı́nez, Á. T., Flores, P., Merino, M., Dobrovic, L., et al. (2024) · Aquaculture · doi:10.1016/j.aquaculture.2024.740803 · Cited by 74 · see citing works
AlMomani, F. A., Hosseinzadeh-Bandbafha, H., Aghbashlo, M., Omar, A., Joo, S., Vasseghian, Y., Karimi‐Maleh, H., Lam, S. S., Tabatabaei, M., & Rezania, S. (2022) · Chemical Engineering Journal · doi:10.1016/j.cej.2022.140588 · Cited by 71 · see citing works
Algae-derived bioactive molecules for the potential treatment of SARS-CoV-2
Alam, M. A., Parra-Saldivar, R., Bilal, M., Afroze, C. A., Ahmed, M. N., Iqbal, H. M. N., & Xu, J. (2021) · Molecules · doi:10.3390/molecules26082134 · Cited by 69 · see citing works
Recent Advances in Astaxanthin as an Antioxidant in Food Applications
Dang, Y., Li, Z., & Yu, F. (2024) · Antioxidants · doi:10.3390/antiox13070879 · Cited by 69 · see citing works
Guo, J., Cui, L., Huang, Y., & Meng, Z. (2022) · Food Research International · doi:10.1016/j.foodres.2022.111815 · Cited by 68 · see citing works
Tahir, F., Ashfaq, H., Khan, A. Z., Amin, M., Akbar, I., Malik, H. A., Abdullah, M., Alessa, A. H., Alsaigh, A. A., Ralph, P. J., et al. (2024) · Reviews in Environmental Science and Bio/Technology · doi:10.1007/s11157-024-09697-0 · Cited by 67 · see citing works
The Importance and Prospects of the Use of Algae in Agribusiness
Piwowar, A., & Harasym, J. (2020) · Sustainability · doi:10.3390/su12145669 · Cited by 67 · see citing works
New Trends in Biotechnological Applications of Photosynthetic Microorganisms
Dawiec-Liśniewska, A., Podstawczyk, D., Bastrzyk, A., Czuba, K., Pacyna-Iwanicka, K., Okoro, O. V., & Shavandi, A. (2022) · Biotechnology Advances · doi:10.1016/j.biotechadv.2022.107988 · Cited by 66 · see citing works
Wang, H., Deng, L., Qi, Z., & Wang, W. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2021.150082 · Cited by 64 · see citing works
Micro-algae: Revolutionizing food production for a healthy and sustainable future
Naik, B., Mishra, R., Kumar, V., Mishra, S., Gupta, U., Rustagi, S., Gupta, A. K., Preet, M. S., Bhatt, S. C., & Rizwanuddin, S. (2024) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2023.100939 · Cited by 65 · see citing works
Production of recombinant and therapeutic proteins in microalgae
Banerjee, A., & Ward, V. C. A. (2022) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2022.102784 · Cited by 64 · see citing works
Disruptive potential of microalgae proteins: Shaping the future of the food industry
Severo, I. A., de Lira, G. S., Ambati, R. R., Gokare, R. A., Vargas, J. V. C., Ordonez, J., & Mariano, A. B. (2024) · Future Foods · doi:10.1016/j.fufo.2024.100318 · Cited by 62 · see citing works
Kselíková, V., Singh, A., Bialevich, V., Čížková, M., & Bišová, K. (2021) · Biotechnology Advances · doi:10.1016/j.biotechadv.2021.107885 · Cited by 61 · see citing works
Lv, K., Yuan, Q., Li, H., Li, T., Ma, H., Gao, C., Zhang, S., Liu, Y., & Zhao, L. (2022) · Foods · doi:10.3390/foods11050725 · Cited by 63 · see citing works
Drying Microalgae Using an Industrial Solar Dryer: A Biomass Quality Assessment
Schmid, B., Navalho, S., Schulze, P. S. C., Walle, S. V. D., Royen, G. V., Schüler, L., Maia, I. B., Bastos, C. R. V., Baune, M., Januschewski, E., et al. (2022) · Foods · doi:10.3390/foods11131873 · Cited by 61 · see citing works
Microbial meat: A sustainable vegan protein source produced from agri-waste to feed the world
Alves, S. C., Díaz-Ruíz, E., Lisboa, B., Sharma, M., Mussatto, S. I., Thakur, V. K., Kalaskar, D. M., Gupta, V. K., & Chandel, A. K. (2023) · Food Research International · doi:10.1016/j.foodres.2023.112596 · Cited by 61 · see citing works
Harnessing genetic engineering to drive economic bioproduct production in algae
Gupta, A., Kang, K., Pathania, R., Saxton, L., Saucedo, B., Malik, A., Torres-Tiji, Y., Diaz, C. J., Dutra Molino, J. V., & Mayfield, S. P. (2024) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2024.1350722 · Cited by 60 · see citing works
Self-citationMicroalgal lipids: biochemistry and biotechnology
Manning, S. R. (2021) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2021.10.018 · Cited by 59 · see citing works
Yang, S., Wang, Y., Wang, J., Cheng, K., Liu, J., He, Y., Zhang, Y., Mou, H., & Sun, H. (2024) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2023.104278 · Cited by 55 · see citing works
Guo, X. J., Wang, Q., Wu, Y., Liu, X., & Gong, Z. (2024) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2024.110112 · Cited by 58 · see citing works
Aditi, Bhardwaj, R., Yadav, A., Swapnil, P., & Meena, M. (2025) · Biotechnology for Biofuels and Bioproducts · doi:10.1186/s13068-025-02612-x · Cited by 61 · see citing works
Carullo, D., Abera, B. D., Scognamiglio, M., Donsı̀, F., Ferrari, G., & Pataro, G. (2022) · Foods · doi:10.3390/foods11030471 · Cited by 57 · see citing works
Helmy, M., Elhalis, H., Liu, Y., Chow, Y., & Selvarajoo, K. (2023) · Advances in Nutrition · doi:10.1016/j.advnut.2022.11.002 · Cited by 54 · see citing works
Fernandes, A. S., Caetano, P. A., Lopes, E. J., Zepka, L. Q., & de Rosso, V. V. (2024) · Food Chemistry · doi:10.1016/j.foodchem.2024.139939 · Cited by 56 · see citing works
Lu, L., Li, F., Gao, Y., Kang, S., Li, J., & Guo, J. (2024) · Molecular Medicine · doi:10.1186/s10020-024-00873-0 · Cited by 59 · see citing works
Wang, M., Zhou, J., Castagnini, J. M., Berrada, H., & Barba, F. J. (2022) · Food Chemistry · doi:10.1016/j.foodchem.2022.134615 · Cited by 55 · see citing works
(EFSA), E. F. S. A., Dujardin, B., de Sousa, R. F., & Ruiz, J. Á. G. (2023) · EFSA Journal · doi:10.2903/j.efsa.2023.7798 · Cited by 55 · see citing works
Bueno, M., Gallego, R., Chourio, A. M., Ibáñez, E., Herrero, M., & Saldaña, M. D. A. (2020) · Innovative Food Science & Emerging Technologies · doi:10.1016/j.ifset.2020.102532 · Cited by 54 · see citing works
Tavakoli, S., Regenstein, J. M., Daneshvar, E., Bhatnagar, A., Luo, Y., & Hong, H. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1895065 · Cited by 54 · see citing works
Production, Processing, and Protection of Microalgal n-3 PUFA-Rich Oil
Ren, X., Liu, Y., Fan, C., Hong, H., Wu, W., Zhang, W. Y., & Wang, Y. (2022) · Foods · doi:10.3390/foods11091215 · Cited by 56 · see citing works
Recent Discoveries on Marine Organism Immunomodulatory Activities
Montuori, E., de Pascale, D., & Lauritano, C. (2022) · Marine Drugs · doi:10.3390/md20070422 · Cited by 54 · see citing works
Ahmed, J., & Kumar, V. (2022) · Algal Research · doi:10.1016/j.algal.2021.102617 · Cited by 53 · see citing works
Gouda, M., Chen, K., Li, X., Liu, Y., & He, Y. (2020) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2020.129229 · Cited by 52 · see citing works
Microalgae as future food: rich nutrients, safety, production costs and environmental effects
Gao, L., Qin, Y., Zhou, X., Jin, W., He, Z., Li, X., & Wang, Q. (2024) · Science of The Total Environment · doi:10.1016/j.scitotenv.2024.172167 · Cited by 55 · see citing works
Stiefvatter, L., Lehnert, K., Frick, K., Montoya‐Arroyo, A., Frank, J., Vetter, W., Schmid‐Staiger, U., & Bischoff, S. C. (2021) · Marine Drugs · doi:10.3390/md19120700 · Cited by 49 · see citing works
- Authors
- Torres-Tiji, Y., Fields, F. J., & Mayfield, S. P.
- Affiliations
- University of California San Diego (US)
- Corresponding author
- Torres-Tiji, Yasin
- Venue
- Biotechnology Advances
- Publisher
- Elsevier BV
- Published
- 2020-07
- Volume
- 41
- Pages
- 107536
- ISSN
- 0734-9750 (ISSN-L)
- OpenAlex
- W3011712150
- Cited by
- 559
- References
- 152
- Citations by year
- 2026: 65 · 2025: 110 · 2024: 114 · 2023: 91 · 2022: 98 · 2021: 62 · 2020: 19
- FWCI
- 3.12
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Biotechnology Advances (acceptedVersion)
- PubMed (publishedVersion)
- OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion)
- Funders
- U.S. Department of Energy (DOEEE0007689)
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Aquaculture Nutrition and Growth
- Life Sciences › Agricultural and Biological Sciences › Food Science › Food Industry and Aquatic Biology
- Keywords
- microalgae, protein-energy malnutrition, malnutrition, genetic engineering of algae, nutritional enhancement, productivity improvement, organoleptic traits, sustainable food supply, alternative protein sources
- MeSH terms
- Agriculture, Food Supply, Genetic Engineering, Humans, Crops, Agricultural, Microalgae
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review