CoChat
Sign Up
Cited by 36

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress

Napoletano, Francesco, Ferrari Bravo, Gloria, Voto, Ilaria Anna Pia, Santin, Aurora, Celora, Lucia, Campaner, Elena, Dezi, Clara, Bertossi, Arianna, Valentino, Elena, Santorsola, Mariangela, Rustighi, Alessandra, Fajner, Valentina, Maspero, Elena, Ansaloni, Federico, Cancila, Valeria, Valenti, Cesare Fabio, Santo, Manuela, Artimagnella, Osvaldo Basilio, Finaurini, Sara, Gioia, Ubaldo, Polo, Simona, Sanges, Remo, Tripodo, Claudio, Mallamaci, Antonello, Gustincich, Stefano, d’Adda di Fagagna, Fabrizio, Mantovani, Fiamma, Specchia, Valeria, Del Sal, Giannino·2021·Cell Reports
DOI 10.1016/j.celrep.2021.109694
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.celrep.2021.109694

Cites

10 of 10 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Show all 10 references

Research works printed but not linked: 92

  1. Allshire, 2018, Ten principles of heterochromatin formation and function, Nat. Rev. Mol. Cell Biol., 19, 229, 10.1038/nrm.2017.119 · DOI
  2. Ansaloni, 2019, Exploratory analysis of transposable elements expression in the C. elegans early embryo, BMC Bioinformatics, 20, 484, 10.1186/s12859-019-3088-7 · DOI
  3. Atchison, 2003, Pin1 regulates the timing of mammalian primordial germ cell proliferation, Development, 130, 3579, 10.1242/dev.00584 · DOI
  4. Bao, 2015, Repbase Update, a database of repetitive elements in eukaryotic genomes, Mob. DNA, 6, 11, 10.1186/s13100-015-0041-9 · DOI
  5. Bertolio, 2019, Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism, Nat. Commun., 10, 1326, 10.1038/s41467-019-09152-7 · DOI
  6. Blalock, 2004, Incipient Alzheimer’s disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses, Proc. Natl. Acad. Sci. USA, 101, 2173, 10.1073/pnas.0308512100 · DOI · Paper page
  7. Blalock, 2011, Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer’s disease, J. Chem. Neuroanat., 42, 118, 10.1016/j.jchemneu.2011.06.007 · DOI · Paper page
  8. Bolger, 2014, Trimmomatic: a flexible trimmer for Illumina sequence data, Bioinformatics, 30, 2114, 10.1093/bioinformatics/btu170 · DOI · Paper page
  9. Buxboim, 2014, Matrix elasticity regulates lamin-A,C phosphorylation and turnover with feedback to actomyosin, Curr. Biol., 24, 1909, 10.1016/j.cub.2014.07.001 · DOI
  10. Chaturvedi, 2010, Lamin A rod domain mutants target heterochromatin protein 1α and β for proteasomal degradation by activation of F-box protein, FBXW10, PLoS ONE, 5, e10620, 10.1371/journal.pone.0010620 · DOI
  11. Campaner, 2017, A covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action, Nat. Commun., 8, 15772, 10.1038/ncomms15772 · DOI
  12. Chaturvedi, 2012, Ubiquitin ligase RNF123 mediates degradation of heterochromatin protein 1α and β in lamin A/C knock-down cells, PLoS ONE, 7, e47558, 10.1371/journal.pone.0047558 · DOI
  13. Chen, 2021, Increased expression of LAP2β eliminates nuclear membrane ruptures in nuclear lamin-deficient neurons and fibroblasts, Proc. Natl. Acad. Sci. USA, 118
  14. Cho, 2019, Mechanosensing by the Lamina Protects against Nuclear Rupture, DNA Damage, and Cell-Cycle Arrest, Dev. Cell, 49, 920, 10.1016/j.devcel.2019.04.020 · DOI
  15. Dobin, 2013, STAR: ultrafast universal RNA-seq aligner, Bioinformatics, 29, 15, 10.1093/bioinformatics/bts635 · DOI · Paper page
  16. Earle, 2020, Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells, Nat. Mater., 19, 464, 10.1038/s41563-019-0563-5 · DOI
  17. Fajner, 2021, The ubiquitin ligase Hecw controls oogenesis and neuronal homeostasis by promoting the liquid state of ribonucleoprotein particles, bioRxiv
  18. Frost, 2016, Lamin Dysfunction Mediates Neurodegeneration in Tauopathies, Curr. Biol., 26, 129, 10.1016/j.cub.2015.11.039 · DOI · Paper page
  19. Gallazzini, 2011, High NaCl-induced activation of CDK5 increases phosphorylation of the osmoprotective transcription factor TonEBP/OREBP at threonine 135, which contributes to its rapid nuclear localization, Mol. Biol. Cell, 22, 703, 10.1091/mbc.e10-08-0681 · DOI
  20. Girardini, 2011, A Pin1/mutant p53 axis promotes aggressiveness in breast cancer, Cancer Cell, 20, 79, 10.1016/j.ccr.2011.06.004 · DOI
  21. Girardini, 2014, Cooperation of p53 mutations with other oncogenic alterations in cancer, Subcell. Biochem., 85, 41, 10.1007/978-94-017-9211-0_3 · DOI
  22. Guastella, 2016, Cartoon filter via adaptive abstraction, J. Vis. Commun. Image Represent., 36, 149, 10.1016/j.jvcir.2016.01.012 · DOI
  23. Guelen, 2008, Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions, Nature, 453, 948, 10.1038/nature06947 · DOI
  24. Guo, 2018, Tau Activates Transposable Elements in Alzheimer’s Disease, Cell Rep, 23, 2874, 10.1016/j.celrep.2018.05.004 · DOI · Paper page
  25. Gyori, 2014, OpenComet: an automated tool for comet assay image analysis, Redox Biol., 2, 457, 10.1016/j.redox.2013.12.020 · DOI
  26. Halfmann, 2019, Repair of nuclear ruptures requires barrier-to-autointegration factor, J. Cell Biol., 218, 2136, 10.1083/jcb.201901116 · DOI
  27. Hildebrand, 2020, Mechanisms and Functions of Chromosome Compartmentalization, Trends Biochem. Sci., 45, 385, 10.1016/j.tibs.2020.01.002 · DOI
  28. Holla, 2020, Positioning Heterochromatin at the Nuclear Periphery Suppresses Histone Turnover to Promote Epigenetic Inheritance, Cell, 180, 150, 10.1016/j.cell.2019.12.004 · DOI
  29. Holzinger, 2009, Jasplakinolide: an actin-specific reagent that promotes actin polymerization, Methods Mol. Biol., 586, 71, 10.1007/978-1-60761-376-3_4 · DOI
  30. Hu, 2011, An integrative approach to ortholog prediction for disease-focused and other functional studies, BMC Bioinformatics, 12, 357, 10.1186/1471-2105-12-357 · DOI · Paper page
  31. Huang, 2009, Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources, Nat. Protoc., 4, 44, 10.1038/nprot.2008.211 · DOI · Paper page
  32. Humphries, 2015, Integrated whole transcriptome and DNA methylation analysis identifies gene networks specific to late-onset Alzheimer’s disease, J. Alzheimers Dis., 44, 977, 10.3233/JAD-141989 · DOI
  33. Johnson, 2004, A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation, Proc. Natl. Acad. Sci. USA, 101, 9677, 10.1073/pnas.0403250101 · DOI
  34. Kaneko, 2011, DICER1 deficit induces alu rna toxicity, 471, 325
  35. Kang, 2015, Drosophila peptidyl-prolyl isomerase Pin1 modulates circadian rhythms via regulating levels of PERIOD, Biochem. Biophys. Res. Commun., 463, 235, 10.1016/j.bbrc.2015.05.033 · DOI
  36. Kidiyoor, 2020, ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration, Nat. Commun., 11, 4828, 10.1038/s41467-020-18580-9 · DOI
  37. Kirby, 2018, Emerging views of the nucleus as a cellular mechanosensor, Nat. Cell Biol., 20, 373, 10.1038/s41556-018-0038-y · DOI
  38. Kourmouli, 2000, Dynamic associations of heterochromatin protein 1 with the nuclear envelope, EMBO J., 19, 6558, 10.1093/emboj/19.23.6558 · DOI
  39. Krishnamoorthy, 2018, E3 ubiquitin ligase HECW2 mediates the proteasomal degradation of HP1 isoforms, Biochem. Biophys. Res. Commun., 503, 2478, 10.1016/j.bbrc.2018.07.003 · DOI
  40. Kumar, 2014, ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress, Cell, 158, 633, 10.1016/j.cell.2014.05.046 · DOI
  41. Lanke, 2018, Integrative analysis of hippocampus gene expression profiles identifies network alterations in aging and Alzheimer’s disease, Front. Aging Neurosci., 10, 153, 10.3389/fnagi.2018.00153 · DOI · Paper page
  42. Larson, 2012, Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis, PLoS Genet., 8, e1002473, 10.1371/journal.pgen.1002473 · DOI · Paper page
  43. Lenz-Böhme, 1997, Insertional mutation of the Drosophila nuclear lamin Dm0 gene results in defective nuclear envelopes, clustering of nuclear pore complexes, and accumulation of annulate lamellae, J. Cell Biol., 137, 1001, 10.1083/jcb.137.5.1001 · DOI
  44. Li, 2009, The Sequence Alignment/Map format and SAMtools, Bioinformatics, 25, 2078, 10.1093/bioinformatics/btp352 · DOI · Paper page
  45. Liou, 2002, Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes, Proc. Natl. Acad. Sci. USA, 99, 1335, 10.1073/pnas.032404099 · DOI
  46. Liou, 2003, Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration, Nature, 424, 556, 10.1038/nature01832 · DOI
  47. Liou, 2011, Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins, Trends Biochem. Sci., 36, 501, 10.1016/j.tibs.2011.07.001 · DOI
  48. Love, 2014, Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2, Genome Biol., 15, 550, 10.1186/s13059-014-0550-8 · DOI · Paper page
  49. Machowska, 2015, Regulation of lamin properties and functions: does phosphorylation do it all?, Open Biol., 5, 150094, 10.1098/rsob.150094 · DOI
  50. Mahmood, 2020, β-actin dependent chromatin remodeling mediates compartment level changes in 3D genome architecture, bioRxiv
  51. Marshall, 2017, Chromatin state changes during neural development revealed by in vivo cell-type specific profiling, Nat. Commun., 8, 2271, 10.1038/s41467-017-02385-4 · DOI
  52. Maspero, 2016, In vitro ubiquitination: Self-ubiquitination, chain formation, and substrate ubiquitination assays, Methods Mol. Biol., 1449, 153, 10.1007/978-1-4939-3756-1_7 · DOI
  53. McCullers, 2017, Transposable elements in Drosophila, Mob. Genet. Elements, 7, 1, 10.1080/2159256X.2017.1318201 · DOI
  54. Meijer, 1997, Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5, Eur. J. Biochem., 243, 527, 10.1111/j.1432-1033.1997.t01-2-00527.x · DOI · Paper page
  55. 2018, Medical image computing and computer assisted intervention – MICCAI 2018
  56. Milbradt, 2016, The Prolyl Isomerase Pin1 Promotes the Herpesvirus-Induced Phosphorylation-Dependent Disassembly of the Nuclear Lamina Required for Nucleocytoplasmic Egress, PLoS Pathog., 12, e1005825, 10.1371/journal.ppat.1005825 · DOI
  57. Napoletano, 2011, Polyglutamine Atrophin provokes neurodegeneration in Drosophila by repressing fat, EMBO J., 30, 945, 10.1038/emboj.2011.1 · DOI
  58. Napoletano, 2017, p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis, PLoS Genet., 13, e1007024, 10.1371/journal.pgen.1007024 · DOI
  59. Nava, 2020, Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage, Cell, 181, 800, 10.1016/j.cell.2020.03.052 · DOI
  60. Payer, 2019, Transposable elements in human genetic disease, Nat. Rev. Genet., 20, 760, 10.1038/s41576-019-0165-8 · DOI
  61. Pindyurin, 2018, The large fraction of heterochromatin in Drosophila neurons is bound by both B-type lamin and HP1a, Epigenetics Chromatin, 11, 65, 10.1186/s13072-018-0235-8 · DOI
  62. Pocaterra, 2019, F-actin dynamics regulates mammalian organ growth and cell fate maintenance, J. Hepatol., 71, 130, 10.1016/j.jhep.2019.02.022 · DOI · Paper page
  63. Poleshko, 2013, The human protein PRR14 tethers heterochromatin to the nuclear lamina during interphase and mitotic exit, Cell Rep., 5, 292, 10.1016/j.celrep.2013.09.024 · DOI
  64. Quinlan, 2010, BEDTools: a flexible suite of utilities for comparing genomic features, Bioinformatics, 26, 841, 10.1093/bioinformatics/btq033 · DOI · Paper page
  65. Raab, 2016, ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death, Science, 352, 359, 10.1126/science.aad7611 · DOI
  66. Robin, 2019, Drosophila p53 integrates the antagonism between autophagy and apoptosis in response to stress, Autophagy, 15, 771, 10.1080/15548627.2018.1558001 · DOI
  67. Rustighi, 2009, The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer, Nat. Cell Biol., 11, 133, 10.1038/ncb1822 · DOI
  68. Rustighi, 2014, Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast, EMBO Mol. Med., 6, 99, 10.1002/emmm.201302909 · DOI
  69. Salvany, 2012, Functional association between eyegone and HP1a mediates wingless transcriptional repression during development, Mol. Cell. Biol., 32, 2407, 10.1128/MCB.06311-11 · DOI
  70. Seugnet, 2009, Aversive phototaxic suppression: evaluation of a short-term memory assay in Drosophila melanogaster, Genes Brain Behav., 8, 377, 10.1111/j.1601-183X.2009.00483.x · DOI
  71. Sharma, 2020, A kinase of many talents: non-neuronal functions of CDK5 in development and disease, Open Biol., 10, 190287, 10.1098/rsob.190287 · DOI
  72. Solovei, 2013, LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation, Cell, 152, 584, 10.1016/j.cell.2013.01.009 · DOI · Paper page
  73. Specchia, 2010, Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons, Nature, 463, 662, 10.1038/nature08739 · DOI
  74. Uchida, 2003, Pin1 and Par14 peptidyl prolyl isomerase inhibitors block cell proliferation, Chem. Biol., 10, 15, 10.1016/S1074-5521(02)00310-1 · DOI
  75. Uhler, 2017, Regulation of genome organization and gene expression by nuclear mechanotransduction, Nat. Rev. Mol. Cell Biol., 18, 717, 10.1038/nrm.2017.101 · DOI
  76. Van Den Brink, 2018, Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila and mice retina, PLoS Genet., 14, e1007627, 10.1371/journal.pgen.1007627 · DOI · Paper page
  77. Vazquez, 2019, SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina, Nucleic Acids Res., 47, 7870, 10.1093/nar/gkz519 · DOI · Paper page
  78. Xie, 2018, β-Actin-dependent global chromatin organization and gene expression programs control cellular identity, FASEB J., 32, 1296, 10.1096/fj.201700753R · DOI
  79. Xie, 2018, β-actin regulates a heterochromatin landscape essential for optimal induction of neuronal programs during direct reprograming, PLoS Genet., 14, e1007846, 10.1371/journal.pgen.1007846 · DOI
  80. Xu, 2011, Actin interaction and regulation of cyclin-dependent kinase 5/p35 complex activity, J. Neurochem., 116, 192, 10.1111/j.1471-4159.2010.06824.x · DOI
  81. Yang, 2019, SQuIRE reveals locus-specific regulation of interspersed repeat expression, Nucleic Acids Res., 47, e27, 10.1093/nar/gky1301 · DOI
  82. Ye, 1996, Interaction between an integral protein of the nuclear envelope inner membrane and human chromodomain proteins homologous to Drosophila HP1, J. Biol. Chem., 271, 14653, 10.1074/jbc.271.25.14653 · DOI
  83. Ye, 1997, Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR, J. Biol. Chem., 272, 14983, 10.1074/jbc.272.23.14983 · DOI
  84. Young, 2020, BAF facilitates interphase nuclear membrane repair through recruitment of nuclear transmembrane proteins, Mol. Biol. Cell, 31, 1551, 10.1091/mbc.E20-01-0009 · DOI
  85. Zacchi, 2002, The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults, Nature, 419, 853, 10.1038/nature01120 · DOI
  86. Zamudio, 2010, Transposable elements in the mammalian germline: a comfortable niche or a deadly trap?, Heredity, 105, 92, 10.1038/hdy.2010.53 · DOI
  87. Zannini, 2019, Oncogenic Hijacking of the PIN1 Signaling Network, Front. Oncol., 9, 94, 10.3389/fonc.2019.00094 · DOI
  88. Zerbino, 2018, Ensembl 2018, Nucleic Acids Res., 46, D754, 10.1093/nar/gkx1098 · DOI · Paper page
  89. Zhang, 2011, Distinct tissue distributions and subcellular localizations of differently phosphorylated forms of the myosin regulatory light chain in Drosophila, Gene Expr. Patterns, 11, 93, 10.1016/j.gep.2010.09.008 · DOI
  90. Zhang, 2019, Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity, Science, 363, eaav2606, 10.1126/science.aav2606 · DOI
  91. Zhang, 2020, The ageing epigenome and its rejuvenation, Nat. Rev. Mol. Cell Biol., 21, 137, 10.1038/s41580-019-0204-5 · DOI · Paper page
  92. Zhou, 2016, The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target, Nat. Rev. Cancer, 16, 463, 10.1038/nrc.2016.49 · DOI

Cited by

Sorted by citations

See all 36

Metadata

Authors
Napoletano, F., Ferrari Bravo, G., Voto, I. A. P., Santin, A., Celora, L., Campaner, E., Dezi, C., Bertossi, A., Valentino, E., Santorsola, M., Rustighi, A., Fajner, V., Maspero, E., Ansaloni, F., Cancila, V., Valenti, C. F., Santo, M., Artimagnella, O. B., Finaurini, S., Gioia, U., Polo, S., Sanges, R., Tripodo, C., Mallamaci, A., Gustincich, S., d’Adda di Fagagna, F., Mantovani, F., Specchia, V., & Del Sal, G.
Venue
Cell Reports
Publisher
Elsevier BV
Published
2021-09
Volume
36
Issue
11
Pages
109694
ISSN
2211-1247
DOI
10.1016/j.celrep.2021.109694
Cited by
36
References
10
Language
en
Licence
Funders
  • Ministero dell’Istruzione, dell’Università e della Ricerca
  • Associazione Italiana per la Ricerca sul Cancro
  • Airc Italian Foundation for Cancer Research (22174, 22759)
  • Fondazione Cariplo (2014-0812)
  • Ministero della Salute (RBFR10V8K6, RF-2019-12368718)
  • European Research Council (21762, TELORNAGING 835103)
  • Fondazione Telethon (21091, 5x1000, FIREQUENCER 875139, GGP17111)
  • Horizon 2020
  • Fondazione per la Ricerca Biomedica (EJP RD COFUND-EJP 825575)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review