Depression in Youth with Autism Spectrum Disorder
Open accessAbstract
Depression is both common and impactful in youth with autism spectrum disorder (ASD) and is swiftly growing in recognition as a major public health concern within the autism community. This article is intended to provide a brief overview of the prevalence, impact, presentation, and risk factors associated with cooccurring depression in children and adolescents with ASD. Clinical guidelines for the assessment and treatment of depression in the ASD population are offered in line with the small existing evidence base.
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Consensus has been reached on which interventions have more supporting evidence, termed naturalistic developmental behavioural interventions.
“Although some consensus has been reached on the interventions that have more supporting evidence (termed 'naturalistic developmental behavio u ral interventions' 171 )”
From Autism spectrum disorder (2020) · cites this paper as [171]
The Treatment of Depression in ASD section describes evidence-based practice as emerging and discusses adapted psychotherapy, but does not identify a consensus category of interventions. Searches for “naturalistic developmental behavioural interventions” and related terms found no passage in our copy addressing that category or the claimed consensus. Page numbers were not available in the indexed copy. (LLM, conf=0.76)
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Emerging Treatments and Therapies for Autism Spectrum Disorder: A Narrative Review
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Neuroticism Drives Associations Between Repetitive Behaviors and Depression in Autistic Adults
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Patterns of Mental Disorders in a Large Child Psychiatric Sample (N = 65,363): A DREAMS Study
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Prevalence and profile of depressive mixed state in patients with autism spectrum disorder
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Exploring the Symptom Profiles of Intolerance of Uncertainty in Autistic Children
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Psychopathologies Associated with ASD: Anxiety, OCD, Depression, and ADHD
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Addressing suicidality in autistic youth: Implications for school mental health professionals
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The importance of social relationships in depression in autistic adolescents: a narrative-review
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Patterns in Medication Use for Treatment of Depression in Autistic Spectrum Disorder
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Transforming the Well-Being of Persons with Autism
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Depressive symptomatology in autism and intellectual disability: A network analysis
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Symptoms of depression in autistic children and adolescents
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Stability and Validity of Self-Reported Depression and Anxiety in Autistic Youth
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Transition-Age Youth with Autism Spectrum Disorder
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Drug-refractory irritability and related factors in autistic children
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Psychometric Properties of Measuring Tools for Depression in Autistic Youths: A Systematic Review
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- Authors
- Pezzimenti, F., Han, G. T., Vasa, R. A., & Gotham, K.
- Affiliations
- Vanderbilt University Medical Center (US)
- Vanderbilt University (US)
- Kennedy Krieger Institute (US)
- Corresponding author
- Gotham, Katherine
- Venue
- Child and Adolescent Psychiatric Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2019-07
- Volume
- 28
- Issue
- 3
- Pages
- 397-409
- ISSN
- 1056-4993 (ISSN-L)
- PMC
- PMC6512853
- OpenAlex
- W2933052044
- Cited by
- 144
- References
- 61
- Citations by year
- 2026: 20 · 2025: 23 · 2024: 27 · 2023: 28 · 2022: 15 · 2021: 20 · 2020: 10 · 2019: 1
- FWCI
- 1.46
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Child and Adolescent Psychiatric Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01-MH113576, K01-MH103500, T32-MH18921)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Keywords
- depression, autism spectrum disorder, youth, children and adolescents, comorbidities, prevalence, risk factors, clinical evaluation, treatment, clinical guidelines
- MeSH terms
- Autism Spectrum Disorder, Adolescent, Child, Depression, Humans, Quality of Life, United States, Comorbidity, Prevalence
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