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Cited by 579Autism Spectrum Disorder ResearchChild and Adolescent Psychosocial and Emotional DevelopmentTreatment of Major Depression

Depression in Persons with Autism: Implications for Research and Clinical Care

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Ghaziuddin, Mohammad, Ghaziuddin, Neera, Greden, John·2002·Journal of Autism and Developmental Disorders
DOI 10.1023/a:1016330802348
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Abstract

Although several studies have investigated the occurrence of medical and neurological conditions in persons with autism, relatively few reports have focused on the phenomenology and treatment of psychiatric disorders in this population. There is emerging evidence that depression is probably the most common psychiatric disorder that occurs in autistic persons. In this review, we examine the factors that influence the presence of depression in this population, such as the level of intelligence, age, gender, associated medical conditions, and the role of genetic factors and life events. We discuss the various forms of treatment available and highlight the need for early detection.

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  • Co-occurring depression among individuals with ASD, especially among those with low IQs, has been associated with an increase in repetitive and restricted behaviors.

    “Co-occurring depression among individuals with ASD, especially among those with low IQs, has been associated with an increase in RRBs (Ghaziuddin et al. 2002).”

    From The Diagnosis of Autism: From Kanner to DSM-III to DSM-5 and Beyond (2021) · cites this paper as Ghaziuddin et al. 2002

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Research works printed but not linked: 5

  1. [5]5. Attwood, A., Frith, U., & Hermelin, B. (1988). The understanding of interpersonal gestures by autistic and Down syndrome chil- dren. Journal of Autism and Developmental Disorders, 18, 241-257.
  2. [41]41. McDougle, C. J. (1998). Repetitive thoughts and behaviors in per- vasive developmental disorders: phenomenology and pharma- cotherapy. In E. Schopler, G. B. Mesibov, & L. J. Kunce (Eds.). Asperger syndrome or High-Functioning Autism (pp. 293-316). New York: Plenum Press.
  3. [48]48. Riddle, M. A. (1987). Individual and parental psychotherapy in autism. In D. J. Cohen, & A. Donnellan (Eds.), Handbook of Autism and Pervasive Developmental Disorders, 1st ed. New York: Wiley, pp. 528-544.
  4. [56]56. Sigman, M., & Mundy, P. (1989). Social attachment in autistic chil- dren. Journal of the American Academy of Child and Adoles- cent Psychiatry, 28, 74 -81.
  5. [61]61. Tantam, D. (1988). Asperger's syndrome. Journal of Child Psy- chology and Psychiatry, 29, 245-253.

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Authors
Ghaziuddin, M., Ghaziuddin, N., & Greden, J.
Affiliations
University of Michigan (US)
Corresponding author
Ghaziuddin, Mohammad
ORCID
Venue
Journal of Autism and Developmental Disorders
Publisher
Springer Science and Business Media LLC
Published
2002-08
Volume
32
Issue
4
Pages
299-306
ISSN
  • 0162-3257 (ISSN-L)
  • 1573-3432
DOI
10.1023/a:1016330802348
OpenAlex
W1546207985
Semantic Scholar
4d8051a1b77a04b327a9b05e8234d2ee7ec4897b
Cited by
579
References
73
Citations by year
2026: 10 · 2025: 13 · 2024: 14 · 2023: 14 · 2022: 22 · 2021: 22 · 2020: 33 · 2019: 34 · 2018: 24 · 2017: 37 · 2016: 37 · 2015: 47 · 2014: 32 · 2013: 45 · 2012: 33
FWCI
0.69
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Autism and Developmental Disorders (publishedVersion)
  • PubMed (publishedVersion)
  • Deep Blue (University of Michigan) (submittedVersion)
Funders
  • Deutsches Krebsforschungszentrum
  • National Alliance for Research on Schizophrenia and Depression
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Keywords
depression, autism spectrum disorder, psychiatric comorbidity, risk factors, intelligence level, gender differences, health conditions, genetic factors, life events, depression treatment, early detection
MeSH terms
Antidepressive Agents, Autistic Disorder, Combined Modality Therapy, Major Depressive Disorder, Depressive Disorder, Major, Humans, Psychotherapy, Comorbidity

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