The role of acetylcholine in learning and memory

Brain-state- and cell-type-specific firing of hippocampal interneurons in vivo

Klausberger, T., Magill, P. J., Márton, L. F., Roberts, J. D. B., Cobden, P. M., Buzsáki, G., & Somogyi, P. (2003) · Nature · doi:10.1038/nature01374 · Cited by 1,345

A proposed function for hippocampal theta rhythm: separate phases of encoding and retrieval enhance reversal of prior learning

Hasselmo, M. E., Bodelón, C., & Wyble, B. P. (2002) · Neural Computation · doi:10.1162/089976602317318965 · Cited by 875

Nicotinic effects on cognitive function: behavioral characterization, pharmacological specification, and anatomic localization

Levin, E. D., McClernon, F. J., & Rezvani, A. H. (2006) · Psychopharmacology · doi:10.1007/s00213-005-0164-7 · Cited by 820

Neuromodulation: acetylcholine and memory consolidation

Hasselmo, M. E. (1999) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(99)01365-0 · Cited by 809

Bidirectional synaptic plasticity induced by a single burst during cholinergic theta oscillation in CA1 in vitro

Huerta, P. T., & Lisman, J. E. (1995) · Neuron · doi:10.1016/0896-6273(95)90094-2 · Cited by 673

Differential regulation of neocortical synapses by neuromodulators and activity

Gil, Z., Connors, B. W., & Amitai, Y. (1997) · Neuron · doi:10.1016/s0896-6273(00)80380-3 · Cited by 553

High acetylcholine levels set circuit dynamics for attention and encoding and low acetylcholine levels set dynamics for consolidation

Hasselmo, M. E., & McGaughy, J. (2004) · Progress in Brain Research · doi:10.1016/s0079-6123(03)45015-2 · Cited by 525

Theta band oscillation and synchrony in the hippocampal formation and associated structures: the case for its role in sensorimotor integration

Bland, B. H., & Oddie, S. D. (2001) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00358-8 · Cited by 520

Laminar selectivity of the cholinergic suppression of synaptic transmission in rat hippocampal region CA1: computational modeling and brain slice physiology

Hasselmo, M., & Schnell, E. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-06-03898.1994 · Cited by 466

Dynamics of learning and recall at excitatory recurrent synapses and cholinergic modulation in rat hippocampal region CA3

Hasselmo, M. E., Schnell, E., & Barkai, E. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-07-05249.1995 · Cited by 463

Vitamin A and Retinoic Acid in Cognition and Cognitive Disease

Wołoszynowska-Fraser, M. U., Kouchmeshky, A., & McCaffery, P. J. A. (2020) · Annual Review of Nutrition · doi:10.1146/annurev-nutr-122319-034227 · Cited by 143

Cholinergic modulation of spatial learning, memory and navigation

Solari, N., & Hangya, B. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.14089 · Cited by 146

The brain in motion: How ensemble fluidity drives memory-updating and flexibility

Mau, W., Hasselmo, M. E., & Cai, D. J. (2020) · eLife · doi:10.7554/elife.63550 · Cited by 148

Cholinergic Blockade Reduces Theta-Gamma Phase Amplitude Coupling and Speed Modulation of Theta Frequency Consistent with Behavioral Effects on Encoding

Newman, E. L., Gillet, S. N., Climer, J. R., & Hasselmo, M. E. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.2586-13.2013 · Cited by 140

Tebuconazole alters morphological, behavioral and neurochemical parameters in larvae and adult zebrafish (Danio rerio)

Altenhofen, S., Nabinger, D. D., Wiprich, M. T., Pereira, T. C. B., Bogo, M. R., & Bonan, C. D. (2017) · Chemosphere · doi:10.1016/j.chemosphere.2017.04.029 · Cited by 135

Regulation of cholinergic activity by the vesicular acetylcholine transporter

Prado, V. F., Roy, A., Kolisnyk, B., Gros, R., & Prado, M. A. M. (2013) · Biochemical Journal · doi:10.1042/bj20121662 · Cited by 137

Cholinergic Modulation of Glial Function During Aging and Chronic Neuroinflammation

Gamage, R. V., Wagnon, I. M., Rossetti, I., Childs, R., Niedermayer, G., Chesworth, R., & Gyengési, E. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.577912 · Cited by 134

A literature review on the neurophysiological underpinnings and cognitive effects of transcutaneous vagus nerve stimulation: challenges and future directions

Colzato, L. S., & Beste, C. (2020) · Journal of Neurophysiology · doi:10.1152/jn.00057.2020 · Cited by 130

Pupil-linked phasic arousal predicts a reduction of choice bias across species and decision domains

de Gee, J. W., Tsetsos, K., Schwabe, L., Urai, A. E., McCormick, D. A., McGinley, M. J., & Donner, T. H. (2020) · eLife · doi:10.7554/elife.54014 · Cited by 135

Tinnitus: Does Gain Explain?

Sedley, W. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.01.027 · Cited by 130

Pupil size signals novelty and predicts later retrieval success for declarative memories of natural scenes

Naber, M., Frässle, S., Rutishauser, U., & Einhäuser, W. (2013) · Journal of Vision · doi:10.1167/13.2.11 · Cited by 146

Sex differences in fear extinction

Velasco, E. R., Florido, A., Milad, M. R., & Andero, R. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.05.020 · Cited by 132

Endosulfan exposure inhibits brain AChE activity and impairs swimming performance in adult zebrafish (Danio rerio)

Pereira, V. M., Bortolotto, J. W., Kist, L. W., de Azevedo, M. B., Fritsch, R. S., Oliveira, R. D. L., Pereira, T. C. B., Bonan, C. D., Vianna, M. R. M. R., & Bogo, M. R. (2012) · NeuroToxicology · doi:10.1016/j.neuro.2012.03.005 · Cited by 128

The cholinergic system and depression

Dagytė, G., den Boer, J. A., & Trentani, A. (2010) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.02.023 · Cited by 127

Muscarinic Receptor Pharmacology and Circuitry for the Modulation of Cognition

Bubser, M., Byun, N. E., Wood, M. R., & Jones, C. K. (2011) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-23274-9_7 · Cited by 130

State-dependencies of learning across brain scales

Ritter, P., Jan Born, A., Brecht, M., Dinse, H. R., Heinemann, U., Pleger, B., Schmitz, D., Schreiber, S., Villringer, A., & Kempter, R. (2015) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2015.00001 · Cited by 123

In situ decorating the surface and interlayer of montmorillonite with Co0.5Ni0.5Fe2O4 nanoparticles: A sustainable, biocompatible colorimetric platform for H2O2 and acetylcholine

Zhu, X., Li, H., Wu, T., Zhao, H. C., Wu, K., Xu, W., Qin, F., Chen, W., Zheng, J., & Liu, Q. (2022) · Nano Research · doi:10.1007/s12274-022-4594-x · Cited by 127

Cortical ChAT+ neurons co-transmit acetylcholine and GABA in a target- and brain-region-specific manner

Granger, A. J., Wang, W., Robertson, K., El-Rifai, M., Zanello, A. F., Bistrong, K., Saunders, A., Chow, B. W., Nuñez, V., Turrero García, M., et al. (2020) · eLife · doi:10.7554/elife.57749 · Cited by 124

Microplastics alone or co-exposed with copper induce neurotoxicity and behavioral alterations on zebrafish larvae after a subchronic exposure

Santos, D., Luzio, A., Matos, C., Bellas, J., Monteiro, S. M., & Félix, L. M. (2021) · Aquatic Toxicology · doi:10.1016/j.aquatox.2021.105814 · Cited by 124

Prediction errors disrupt hippocampal representations and update episodic memories

Sinclair, A. H., Manalili, G. M., Brunec, I. K., Adcock, R. A., & Barense, M. D. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2117625118 · Cited by 145

Toward an integration of deep learning and neuroscience

Marblestone, A. H., Wayne, G., & Kording, K. P. (2016) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2016.00094 · Cited by 119

Dopamine Precursor Depletion Impairs Timing in Healthy Volunteers by Attenuating Activity in Putamen and Supplementary Motor Area

Coull, J. T., Hwang, H. J., Leyton, M., & Dagher, A. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.1258-12.2012 · Cited by 119

Switching between internal and external modes: A multiscale learning principle

Honey, C. J., Newman, E. L., & Schapiro, A. C. (2017) · Network Neuroscience · doi:10.1162/netn_a_00024 · Cited by 115

Impairments of spatial memory in an Alzheimer’s disease model via degeneration of hippocampal cholinergic synapses

Zhu, H., Yan, H., Tang, N., Li, X., Pang, P., Li, H., Chen, W., Guo, Y. A., Shu, S., Cai, Y., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-01943-0 · Cited by 121

Spatiotemporal Coupling between Hippocampal Acetylcholine Release and Theta OscillationsIn Vivo

Zhang, H., Lin, S., & Nicolelis, M. A. L. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1144-10.2010 · Cited by 118

A novel touchscreen-automated paired-associate learning (PAL) task sensitive to pharmacological manipulation of the hippocampus: a translational rodent model of cognitive impairments in neurodegenerative disease

Talpos, J. C., Winters, B. D., Dias, R. S., Saksida, L. M., & Bussey, T. J. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1526-3 · Cited by 122

Cholinergic control of GABA release: emerging parallels between neocortex and hippocampus

Lawrence, J. J. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2008.03.008 · Cited by 115

The Neuron Identity Problem: Form Meets Function

Fishell, G., & Heintz, N. (2013) · Neuron · doi:10.1016/j.neuron.2013.10.035 · Cited by 115

Effects of combined treatment with vitamins C and E on passive avoidance learning and memory in diabetic rats

Hasanein, P., & Shahidi, ‬. (2010) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2010.01.004 · Cited by 115

Enhancing plasticity in central networks improves motor and sensory recovery after nerve damage

Meyers, E., Kasliwal, N., Solorzano, B. R., Lai, E., Bendale, G. S., Berry, A., Ganzer, P. D., Romero‐Ortega, M. I., Rennaker, R. L., Kilgard, M. P., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-13695-0 · Cited by 115

Acetylcholinesterase Inhibitory Potential of Various Sesquiterpene Analogues for Alzheimer’s Disease Therapy

Arya, A., Chahal, R., Rao, R., Rahman, M. H., Kaushik, D., Akhtar, M. F., Saleem, A., Khalifa, S. M. A., El-Seedi, H. R., Kamel, M., et al. (2021) · Biomolecules · doi:10.3390/biom11030350 · Cited by 111

Cholinergic modulation of multivesicular release regulates striatal synaptic potency and integration

Higley, M. J., Soler-Llavina, G. J., & Sabatini, B. L. (2009) · Nature Neuroscience · doi:10.1038/nn.2368 · Cited by 110

Forebrain Cholinergic Signaling: Wired and Phasic, Not Tonic, and Causing Behavior

Sarter, M. F., & Lustig, C. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.1305-19.2019 · Cited by 118

Neuroprotective effects of Syringic acid against aluminium chloride induced oxidative stress mediated neuroinflammation in rat model of Alzheimer's disease

Zhao, Y., Dang, M., Zhang, W., Lei, Y., Ramesh, T., Veeraraghavan, V. P., & Hou, X. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104009 · Cited by 116

State of the art on insect nicotinic acetylcholine receptor function in learning and memory.

Gauthier, M. (2010) · Advances in Experimental Medicine and Biology · doi:10.1007/978-1-4419-6445-8_9 · Cited by 103

Adenosine A2A receptor blockade prevents memory dysfunction caused by β-amyloid peptides but not by scopolamine or MK-801

Cunha, G. M. A., Canas, P. M., Melo, C. S., Hockemeyer, J., Müller, C. E., Oliveira, C. R., & Cunha, R. A. (2007) · Experimental Neurology · doi:10.1016/j.expneurol.2007.11.013 · Cited by 109

Cholinergic influences on cortical development and adult neurogenesis

Bruel‐Jungerman, E., Lucassen, P. J., & Francis, F. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.01.021 · Cited by 114

Plants-derived neuroprotective agents: cutting the cycle of cell death through multiple mechanisms

Elufioye, T. O., Berida, T. I., & Habtemariam, S. (2017) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2017/3574012 · Cited by 107

Deep brain stimulation of the forniceal area enhances memory functions in experimental dementia: The role of stimulation parameters

Hescham, S., Lim, L. W., Jahanshahi, A., Steinbusch, H. W. M., Prickaerts, J., Blokland, A., & Temel, Y. (2012) · Brain stimulation · doi:10.1016/j.brs.2012.01.008 · Cited by 106

Effects of harmine, an acetylcholinesterase inhibitor, on spatial learning and memory of APP/PS1 transgenic mice and scopolamine-induced memory impairment mice

He, D., Wu, H., Wei, Y., Liu, W., Huang, F., Shi, H., Zhang, B., Wu, X., & Wang, C. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.10.037 · Cited by 105

Failing to Ignore: Paradoxical Neural Effects of Perceptual Load on Early Attentional Selection in Normal Aging

Schmitz, T. W., Cheng, F. H. T., & Rosa, E. D. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.2687-10.2010 · Cited by 113

A novel pyramidal cell type promotes sharp-wave synchronization in the hippocampus

Hunt, D. L., Linaro, D., Si, B., Romani, S., & Spruston, N. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0172-7 · Cited by 109

Cholinergic suppression of hippocampal sharp-wave ripples impairs working memory

Zhang, Y., Cao, L., Varga, V., Jing, M., Karadas, M., Li, Y., & Buzsáki, G. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2016432118 · Cited by 111

Cognitive Aging: A Common Decline of Episodic Recollection and Spatial Memory in Rats

Robitsek, R. J., Fortin, N. J., Koh, M. T., Gallagher, M., & Eichenbaum, H. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.1893-08.2008 · Cited by 103

Mnemonic prediction errors bias hippocampal states

Bein, O., Duncan, K. D., & Davachi, L. (2020) · Nature Communications · doi:10.1038/s41467-020-17287-1 · Cited by 103

An insula hierarchical network architecture for active interoceptive inference

Fermin, A. S. R., Friston, K., & Yamawaki, S. (2022) · Royal Society Open Science · doi:10.1098/rsos.220226 · Cited by 101

Cholinergic Enhancement Reduces Spatial Spread of Visual Responses in Human Early Visual Cortex

Silver, M. A., Shenhav, A., & D'Esposito, M. (2008) · Neuron · doi:10.1016/j.neuron.2008.09.038 · Cited by 100

Neuromodulators and Long-Term Synaptic Plasticity in Learning and Memory: A Steered-Glutamatergic Perspective

Bazzari, A. H., & Parri, H. R. (2019) · Brain Sciences · doi:10.3390/brainsci9110300 · Cited by 107

M3 Muscarinic Acetylcholine Receptor Expression Confers Differential Cholinergic Modulation to Neurochemically Distinct Hippocampal Basket Cell Subtypes

Cea-del Rio, C. A., Lawrence, J. J., Tricoire, L., Erdelyi, F., Szabo, G., & McBain, C. J. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.5040-09.2010 · Cited by 99

Hippocampal Place Cell Firing Patterns Can Induce Long-Term Synaptic Plasticity In Vitro

Isaac, J. T. R., Buchanan, K. A., Muller, R. U., & Mellor, J. R. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.0731-09.2009 · Cited by 100

The Neuropsychology of Anxiety

McNaughton, N., & Gray, J. A. (2024) · doi:10.1093/oso/9780198843313.001.0001 · Cited by 99

New perspectives on the basal forebrain cholinergic system in Alzheimer’s disease

Berry, A. S., & Harrison, T. M. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105192 · Cited by 102

A specific role for septohippocampal acetylcholine in memory?

Easton, A., Douchamps, V., Eacott, M. J., & Lever, C. (2012) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2012.07.022 · Cited by 106

A fast genetically encoded fluorescent sensor for faithful in vivo acetylcholine detection in mice, fish, worms and fliesPreprint

Borden, P. M., Zhang, P., Shivange, A. V., Marvin, J. S., Cichon, J., Dan, C., Podgorski, K., Figueiredo, A. M. P. D., Novák, O., Tanimoto, M., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.02.07.939504 · Cited by 98

Phellodendron amurenseand Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats

Lee, B., Sur, B., Shim, I., Lee, H., & Hahm, D. (2012) · Korean Journal of Physiology and Pharmacology · doi:10.4196/kjpp.2012.16.2.79 · Cited by 96

Such stuff as dreams are made on? Elaborative encoding, the ancient art of memory, and the hippocampus

Llewellyn, S. (2013) · Behavioral and Brain Sciences · doi:10.1017/s0140525x12003135 · Cited by 95

Layer-specific cholinergic control of human and mouse cortical synaptic plasticity

Verhoog, M. B., Obermayer, J., Kortleven, C., Wilbers, R., Wester, J., Baayen, J. C., de Kock, C. P. J., Meredith, R. M., & Mansvelder, H. D. (2016) · Nature Communications · doi:10.1038/ncomms12826 · Cited by 104

How Hippocampal Memory Shapes, and Is Shaped by, Attention

Aly, M., & Turk-Browne, N. B. (2017) · The Hippocampus from Cells to Systems · doi:10.1007/978-3-319-50406-3_12 · Cited by 97

The effects of cholinergic neuromodulation on neuronal phase-response curves of modeled cortical neurons

Stiefel, K. M., Gutkin, B. S., & B, T. J. S. A. (2008) · Journal of Computational Neuroscience · doi:10.1007/s10827-008-0111-9 · Cited by 95

Spike–wave discharges in adult Sprague–Dawley rats and their implications for animal models of temporal lobe epilepsy

Pearce, P. S., Friedman, D. J., LaFrancois, J. J., Iyengar, S. S., Fenton, A. A., MacLusky, N. J., & Scharfman, H. E. (2014) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2014.01.004 · Cited by 93

Distinct synaptic properties of perisomatic inhibitory cell types and their different modulation by cholinergic receptor activation in the CA3 region of the mouse hippocampus

Szabo, G. G., Holderith, N. B., Gulyás, A. I., Freund, T. F., & Hájos, N. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07292.x · Cited by 94

Acupuncture stimulation improves scopolamine-induced cognitive impairment via activation of cholinergic system and regulation of BDNF and CREB expressions in rats

Lee, B., Sur, B., Shim, J., Hahm, D., & Lee, H. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-338 · Cited by 92

A Unified Dynamic Model for Learning, Replay, and Sharp-Wave/Ripples

Jahnke, S., Timme, M., & Memmesheimer, R.-M. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.3977-14.2015 · Cited by 90

Focused ultrasound-induced blood-brain barrier opening improves adult hippocampal neurogenesis and cognitive function in a cholinergic degeneration dementia rat model

Shin, J., Kong, C., Lee, J., Choi, B. Y., Sim, J., Koh, C. S., Park, M., Na, Y. C., Suh, S. W., Chang, W. S., et al. (2019) · Alzheimer s Research & Therapy · doi:10.1186/s13195-019-0569-x · Cited by 93

Characterization and Exploration of Potential Neuroprotective Peptides in Walnut ( Juglans regia ) Protein Hydrolysate against Cholinergic System Damage and Oxidative Stress in Scopolamine-Induced Cognitive and Memory Impairment Mice and Zebrafish

Wang, S., Su, G., Zhang, X., Song, G., Zhang, L., Zheng, L. P., & Zhao, M. (2021) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c07798 · Cited by 92

Persistent Sodium Current Drives Conditional Pacemaking in CA1 Pyramidal Neurons under Muscarinic Stimulation

Yamada-Hanff, J., & Bean, B. P. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0577-13.2013 · Cited by 94

Transforming Sensory Cues into Aversive Emotion via Septal-Habenular Pathway

Zhang, G., Shen, L., Zhong, W., Xiong, Y., Zhang, L. I., & Tao, H. W. (2018) · Neuron · doi:10.1016/j.neuron.2018.07.023 · Cited by 95

Action Mechanisms of Curcumin in Alzheimer’s Disease and Its Brain Targeted Delivery

Ege, D. (2021) · Materials · doi:10.3390/ma14123332 · Cited by 97

Cognitive Enhancers (Nootropics). Part 1: Drugs Interacting with Receptors

Froestl, W., Muhs, A., & Pfeifer, A. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-121186 · Cited by 94

Alzheimer’s disease and its treatment–yesterday, today, and tomorrow

Kim, A. Y., Jerdi, S. A., MacDonald, R., & Triggle, C. R. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1399121 · Cited by 99

Nootropic, anxiolytic and CNS-depressant studies on different plant sources ofshankhpushpi

Malik, J., Karan, M., & Vasisht, K. (2011) · Pharmaceutical Biology · doi:10.3109/13880209.2011.584539 · Cited by 89

Selectionist and Evolutionary Approaches to Brain Function: A Critical Appraisal

Fernando, C., Szathmáry, E., & Husbands, P. (2012) · Frontiers in Computational Neuroscience · doi:10.3389/fncom.2012.00024 · Cited by 90

From the cell to the clinic: A comparative review of the partial D2/D3 receptor agonist and α2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease

Millan, M. J. (2010) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2010.06.002 · Cited by 92

Modulation of Hippocampal Circuits by Muscarinic and Nicotinic Receptors

Dannenberg, H., Young, K., & Hasselmo, M. E. (2017) · Frontiers in Neural Circuits · doi:10.3389/fncir.2017.00102 · Cited by 89

Age-dependent disruption in hippocampal theta oscillation in amyloid-β overproducing transgenic mice

Scott, L., Feng, J., Kiss, T., Needle, E., Atchison, K. P., Kawabe, T. T., Milici, A. J., Hajós‐Korcsok, É., Riddell, D. R., & Hajós, M. (2012) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.12.010 · Cited by 93

Alzheimer's disease and age-related memory decline (preclinical)

Terry, A. V., Callahan, P. M., Hall, B. J., & Webster, S. J. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.02.002 · Cited by 86

Reevaluating the Role of Persistent Neural Activity in Short-Term Memory

Masse, N. Y., Rosen, M. C., & Freedman, D. J. (2020) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2019.12.014 · Cited by 84

Differential Relation between Neuronal and Behavioral Discrimination during Hippocampal Memory Encoding

Allegra, M., Posani, L., Gómez-Ocádiz, R., & Schmidt‐Hieber, C. (2020) · Neuron · doi:10.1016/j.neuron.2020.09.032 · Cited by 83

Naturally Occurring Antioxidant Therapy in Alzheimer’s Disease

Collins, A. E., Saleh, T. M., & Kalisch, B. E. (2022) · Antioxidants · doi:10.3390/antiox11020213 · Cited by 93

In Pursuit of Healthy Aging: Effects of Nutrition on Brain Function

Melzer, T. M., Manosso, L. M., Yau, S., Gil‐Mohapel, J., & Brocardo, P. S. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22095026 · Cited by 97

Donepezil Protects Against Doxorubicin-Induced Chemobrain in Rats via Attenuation of Inflammation and Oxidative Stress Without Interfering With Doxorubicin Efficacy

Ongnok, B., Khuanjing, T., Chunchai, T., Pantiya, P., Kerdphoo, S., Arunsak, B., Nawara, W., Jaiwongkam, T., Apaijai, N., Chattipakorn, N., et al. (2021) · Neurotherapeutics · doi:10.1007/s13311-021-01092-9 · Cited by 86

Acetylcholine deficiency disrupts extratelencephalic projection neurons in the prefrontal cortex in a mouse model of Alzheimer’s disease

Sun, Q., Zhang, J., Li, A., Yao, M., Liu, G., Chen, S., Luo, Y., Wang, Z., Gong, H., Li, X., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28493-4 · Cited by 87

Working memory capacity as a moderator of load-related frontal midline theta variability in Sternberg task

Zakrzewska, M., & Brzezicka, A. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00399 · Cited by 84

Supramammillary nucleus synchronizes with dentate gyrus to regulate spatial memory retrieval through glutamate release

Li, Y., Bao, H., Luo, Y., Chérasse, Y., Sullivan, H. A., Quintanilla, L., Wickersham, I. R., Lazarus, M., Shih, Y. I., & Song, J. (2020) · eLife · doi:10.7554/elife.53129 · Cited by 83

Hyperglycemia induces memory impairment linked to increased acetylcholinesterase activity in zebrafish (Danio rerio)

Capiotti, K. M., Moraes, D. A. D., Menezes, F. P., Kist, L. W., Bogo, M. R., & da Silva, R. S. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.08.033 · Cited by 81

Tanshinone congeners improve memory impairments induced by scopolamine on passive avoidance tasks in mice

Kim, D. H., Jeon, S. J., Jung, J. W., Lee, S., Yoon, B. H., Shin, B. Y., Son, K. H., Cheong, J. H., Kim, Y. S., Kang, S. S., et al. (2007) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2007.07.042 · Cited by 81

Estrogens and memory in physiological and neuropathological conditions

Pompili, A., Arnone, B., & Gasbarri, A. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2012.01.007 · Cited by 84

Cholinergic Stimulation Enhances Neural Activity Associated with Encoding but Reduces Neural Activity Associated with Retrieval in Humans

Kukolja, J., Thiel, C. M., & Fink, G. R. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.0203-09.2009 · Cited by 86

Evaluation of a Combined Therapeutic Regimen of 8-OH-DPAT and Environmental Enrichment after Experimental Traumatic Brain Injury

Kline, A. E., McAloon, R. L., Henderson, K. A., Bansal, U. K., Ganti, B. M., Ahmed, R. H., Gibbs, R. B., & Sozda, C. N. (2010) · Journal of Neurotrauma · doi:10.1089/neu.2010.1535 · Cited by 80

Fast gamma rhythms in the hippocampus promote encoding of novel object-place pairings

Zheng, C., Bieri, K. W., Hwaun, E., & Colgin, L. L. (2016) · eNeuro · doi:10.1523/eneuro.0001-16.2016 · Cited by 79

Impact of perinatal hypoxia on the developing brain

Piešová, M., & Mach, M. (2020) · Physiological Research · doi:10.33549/physiolres.934198 · Cited by 88

Brain activity is not only for thinking

Laumann, T. O., & Snyder, A. Z. (2021) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2021.04.002 · Cited by 78

Offline memory consolidation during waking rest

Wamsley, E. J. (2022) · Nature Reviews Psychology · doi:10.1038/s44159-022-00072-w · Cited by 84

Possible role of acetylcholine in regulating spatial novelty effects on theta rhythm and grid cells

Barry, C., Heys, J. G., & Hasselmo, M. E. (2012) · Frontiers in Neural Circuits · doi:10.3389/fncir.2012.00005 · Cited by 81

The role of acetylcholine in negative encoding bias: Too much of a good thing?

Mineur, Y. S., & Picciotto, M. R. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.14641 · Cited by 78

The short- and long-term effects of orally administered high-dose reduced graphene oxide nanosheets on mouse behaviors

Zhang, D., Zhang, Z., Liu, Y., Chu, M., Yang, C., Li, W., Shao, Y., Yue, Y., & Xu, R. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.07.060 · Cited by 78

Nicotinic mechanisms influencing synaptic plasticity in the hippocampus

Placzek, A. N., Zhang, T. A., & Dani, J. A. (2009) · Acta Pharmacologica Sinica · doi:10.1038/aps.2009.39 · Cited by 77

Modeling new neuron function: a history of using computational neuroscience to study adult neurogenesis

Aimone, J. B., & Gage, F. H. (2011) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2011.07615.x · Cited by 79

Boosting visual cortex function and plasticity with acetylcholine to enhance visual perception

Kang, J. I., Huppé‐Gourgues, F., & Vaucher, E. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00172 · Cited by 75

Acetylcholine and the complex interdependence of memory and attention

Decker, A. L., & Duncan, K. D. (2020) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2020.01.013 · Cited by 85

Septohippocampal acetylcholine and theta oscillations can modulate memory encoding and retrieval: Insights from a neural masses network

Pirazzini, G., & Ursino, M. (2025) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2025.111465 · Cited by 4

Enhanced cholinergic suppression of previously strengthened synapses enables the formation of self-organized representations in olfactory cortex

Linster, C., Maloney, M. E., Patil, M. M., & Hasselmo, M. E. (2003) · Neurobiology of Learning and Memory · doi:10.1016/s1074-7427(03)00078-9 · Cited by 56

Acetylcholine and memory

Hasselmo, M. E., & Bower, J. M. (1993) · Trends in Neurosciences · doi:10.1016/0166-2236(93)90159-j · Cited by 429

Cholinergic-sensitive theta oscillations in memory encoding in mice

Gu, Z., Stevanovic, K. D., Cushman, J. D., & Yakel, J. L. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.1313-23.2024 · Cited by 4

The Critical Role of Cholinergic Basal Forebrain Neurons in Morphological Change and Memory Encoding: A Hypothesis

Woolf, N. J. (1996) · Neurobiology of Learning and Memory · doi:10.1006/nlme.1996.0068 · Cited by 60