A systematic review of unified protocol applications with adult populations: facilitating widespread dissemination via adaptability

Cassiello-Robbins, Clair; Southward, Matthew W.; Tirpak, Julianne Wilner; Sauer-Zavala, Shannon

doi:10.1016/j.cpr.2020.101852

Cited by 179Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPersonality Disorders and PsychopathologyPsychotherapy Techniques and Applications

A systematic review of unified protocol applications with adult populations: facilitating widespread dissemination via adaptability

Cassiello-Robbins, Clair, Southward, Matthew W., Tirpak, Julianne Wilner, Sauer-Zavala, Shannon·2020·Clinical Psychology Review

DOI 10.1016/j.cpr.2020.101852

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Abstract

The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) was designed to be a flexible, evidence-based intervention that could treat a wide range of emotional disorders. The purpose of this systematic review is to summarize (1) the range of presenting problems to which the UP has been applied with adult patients, and (2) the settings in which the protocol has been used, as well as any modifications made to it. Using PRISMA guidelines, we conducted a literature search of PsychInfo, PubMed, Proquest Dissertations and Theses, and Web of Science. The 77 studies included in this review indicated the UP has been applied to a wide range of presenting problems including anxiety, depressive, bipolar, traumatic-stressor, substance use, eating, borderline personality, insomnia, and physical health disorders. Additionally, the UP has been applied to non-diagnosable problems such as non-suicidal self-injury, subclinical presentations, and sexual minority stress. The strongest base of evidence for the UP is among Caucasian females in the United States with anxiety-related or depressive disorders. Numerous adaptions of the UP were present in the literature. Overall, results suggest the UP can be flexibly applied to a range of diagnostic presentations. However, many studies reviewed were preliminary and further research is needed.

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The UP is a highly modifiable intervention that can promote regulatory flexibility by integrating other coping skills such as acceptance and self-compassion.
“the UP is a highly modifiable intervention that affords the opportunity to promote regulatory flexibility by integrating other coping skills, such as acceptance and self-compassion”
From RESILIENCE, COPING, AND THE COVID-19 PANDEMIC ACROSS THE GLOBE – AN UPDATE: WHAT HAVE WE LEARNED? (2023) · cites this paper as Cassiello-Robbins et al., 2020
A growing evidence base supports the utility of the UP for improving emotional and emotion-adjacent symptoms, including anxiety, depression, anger, substance misuse, self-injury, somatization, obsessive-compulsive symptoms, and trauma-related symptoms.
“A growing evidence base supports the utility of the UP for improving emotional and emotion-adjacent symptoms, including anxiety, depression, anger, substance misuse, self-injury, somatization, obsessive-compulsive symptoms, and trauma-related symptoms (26, 31–37).”
From Pilot outcomes and exploration of treatment mechanisms using a culturally adapted version of the unified protocol for transdiagnostic treatment of emotional disorders to improve mental health symptoms, alcohol misuse, functional outcomes, and sleep quality in emergency responders (2025) · cites this paper as [33]
Recent systematic reviews and meta-analysis evidence that the UP could help to manage EDs in the general population.
“Recent systematic reviews and meta-analysis evidence that the UP could help to manage EDs in the general population (Sakiris and Berle, 2019; Cassiello-Robbins et al., 2020; Carlucci et al., 2021; Longley and Gleiser, 2023) and also in individuals with comorbid medical conditions such as those living with Human Immunodeficiency Virus (HIV), cancer, chronic pain or multiple sclerosis, among others”
From Unified Protocol for the transdiagnostic treatment of emotional disorders in people with post COVID-19 condition: study protocol for a multiple baseline n-of-1 trial (2023) · cites this paper as Cassiello-Robbins et al., 2020
The most recent systematic review identified 77 studies indicating support for the UP's suitability to a wide range of psychological conditions and non-diagnosable problems.
“The most recent systematic review (Cassiello-Robbins et al., 2020) identified 77 studies indicating support for the UP’s suitability to a wide range of psychological conditions (i.e., 9 types of disorders), and also non-diagnosable problems.”
From Can We Boost Treatment Adherence to an Online Transdiagnostic Intervention by Adding Self-Enhancement Strategies? Results From a Randomized Controlled Non-inferiority Trial (2021) · cites this paper as Cassiello-Robbins et al., 2020
The UP's efficacy, effectiveness and generalizability rely on a large and robust body of evidence.
“The protocol’s efficacy, effectiveness and generalizability already rely on a large and robust body of evidence (see Sakiris and Berle, 2019; Cassiello-Robbins et al., 2020 for reviews and meta-analyses).”
From Can We Boost Treatment Adherence to an Online Transdiagnostic Intervention by Adding Self-Enhancement Strategies? Results From a Randomized Controlled Non-inferiority Trial (2021) · cites this paper as Cassiello-Robbins et al., 2020

Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859 · see citing works
Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & the PRISMA Group* (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00135 · Cited by 37,554 · see citing works
Prevalence, Severity, and Comorbidity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication
Kessler, R. C., Chiu, W. T., Demler, O., & Walters, E. E. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.6.617 · Cited by 12,052 · see citing works
The file drawer problem and tolerance for null results.
Rosenthal, R. (1979) · Psychological Bulletin · doi:10.1037/0033-2909.86.3.638 · Cited by 9,068 · cited 1× · see citing works
“That is, it is not possible to know how many studies were conducted but not reported (Rosenthal, 1979).”
Background
False-Positive Psychology: Undisclosed Flexibility in Data Collection and Analysis Allows Presenting Anything as Significant
Simmons, J. P., Nelson, L. D., & Simonsohn, U. (2011) · Psychological Science · doi:10.1177/0956797611417632 · Cited by 6,567 · see citing works
Diagnostic and Statistical Manual of Mental Disorders
Siegel, L. J., & Fletcher‐Janzen, E. (2014) · Wiley eBooks · doi:10.1002/9781118660584.ese0728 · Cited by 3,438 · see citing works
Functional Neuroimaging of Anxiety: A Meta-Analysis of Emotional Processing in PTSD, Social Anxiety Disorder, and Specific Phobia
Etkin, A., & Wager, T. D. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.07030504 · Cited by 3,391 · see citing works
Reciprocal Limbic-Cortical Function and Negative Mood: Converging PET Findings in Depression and Normal Sadness
Mayberg, H. S., Liotti, M., Brannan, S. K., McGinnis, S., Mahurin, R. K., Jerabek, P. A., Silva, J. A., Tekell, J. L., Martin, C. C., Lancaster, J. L., et al. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.5.675 · Cited by 2,416 · see citing works
The Neurocircuitry of Fear, Stress, and Anxiety Disorders
Shin, L. M., & Liberzon, I. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.83 · Cited by 2,083 · cited 1× · see citing works
“…features including overlap in diagnostic criteria (Brown & Barlow, 2009) and common neurobiological mechanisms (e.g., hyperexcitability of limbic structures and limited inhibitory control by cortical structures; Etkin & Wager, 2007; Mayberg et al., 1999; Porto et al., 2009; Shin & Liberzon, 2010).”
Background
Current and lifetime comorbidity of the DSM-IV anxiety and mood disorders in a large clinical sample.
Brown, T. A., Campbell, L. A., Lehman, C. L., Grisham, J. R., & Mancill, R. B. (2001) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.110.4.585 · Cited by 1,562 · see citing works
Toward a unified treatment for emotional disorders
Barlow, D. H., Allen, L. B., & Choate, M. L. (2004) · Behavior Therapy · doi:10.1016/s0005-7894(04)80036-4 · Cited by 1,430 · see citing works
Untitled work
(2008) · Cited by 1,397 · see citing works
Systematic Review of the Effects of Shared Decision-Making on Patient Satisfaction, Treatment Adherence and Health Status
Joosten, E. A. G., DeFuentes-Merillas, L., de Weert, G. H., Sensky, T., van der Staak, C. P. F., & de Jong, C. A. J. (2008) · Psychotherapy and Psychosomatics · doi:10.1159/000126073 · Cited by 1,135 · see citing works
The Future of Intervention Science: Process-Based Therapy
Hofmann, S. G., & Hayes, S. C. (2019) · Clinical Psychological Science · doi:10.1177/2167702618772296 · Cited by 888 · see citing works
Untitled work
(2010) · Cited by 874 · see citing works
The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders Compared With Diagnosis-Specific Protocols for Anxiety Disorders: A Randomized Clinical Trial
Barlow, D. H., Farchione, T. J., Bullis, J. R., Gallagher, M. W., Murray-Latin, H., Sauer-Zavala, S., Bentley, K. H., Thompson-Hollands, J., Conklin, L. R., Boswell, J. F., et al. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.2164 · Cited by 853 · see citing works
Self-citation
Barriers to help-seeking by men: a review of sociocultural and clinical literature with particular reference to depression
Möller-Leimkühler, A. M. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(01)00379-2 · Cited by 851 · cited 2× · see citing works
“, depression, anxiety-related, borderline personality, eating disorders) are more common in female populations (Kessler, Chiu, Demler, & Walters, 2005), and data suggest women seek treatment at higher rates than men (Möller-Leimkühler, 2002).”
Background
The Nature, Diagnosis, and Treatment of Neuroticism: Back to the Future
Barlow, D. H., Sauer-Zavala, S., Carl, J. R., Bullis, J. R., & Ellard, K. K. (2014) · Clinical Psychological Science · doi:10.1177/2167702613505532 · Cited by 850 · see citing works
Self-citation
Cognitive Behavior Therapy and Eating Disorders
Weiss, F. (2008) · American Journal of Psychotherapy · doi:10.1176/appi.psychotherapy.2008.62.4.422 · Cited by 838 · see citing works
Testing Standard and Modular Designs for Psychotherapy Treating Depression, Anxiety, and Conduct Problems in Youth: A Randomized Effectiveness Trial
Weisz, J. R. (2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.147 · Cited by 827 · cited 1× · see citing works
“Modular treatments have demonstrated steeper trajectories of improvement compared to traditional manualized treatment suggesting this approach improves treatment efficiency (Weisz et al., 2012).”
Background
Clinical Handbook of Psychological Disorders: A Step-by-Step Treatment Manual
Barnaby, B. (2015) · Occupational Medicine · doi:10.1093/occmed/kqv128 · Cited by 816 · see citing works
The psychotherapy dose-response effect and its implications for treatment delivery services.
Hansen, N. B., Lambert, M. J., & Forman, E. M. (2002) · Clinical Psychology: Science and Practice · doi:10.1093/clipsy.9.3.329 · Cited by 783 · see citing works
Unified Protocol for Transdiagnostic Treatment of Emotional Disorders: A Randomized Controlled Trial
Farchione, T. J., Fairholme, C. P., Ellard, K. K., Boisseau, C. L., Thompson-Hollands, J., Carl, J. R., Gallagher, M. W., & Barlow, D. H. (2012) · Behavior Therapy · doi:10.1016/j.beth.2012.01.001 · Cited by 746 · see citing works
A proposal for a dimensional classification system based on the shared features of the DSM-IV anxiety and mood disorders: implications for assessment and treatment
Brown, T. A., & Barlow, D. H. (2009) · Psychological Assessment · doi:10.1037/a0016608 · Cited by 639 · see citing works
Acceptability and suppression of negative emotion in anxiety and mood disorders.
Campbell-Sills, L., Barlow, D. H., Brown, T. A., & Hofmann, S. G. (2006) · Emotion · doi:10.1037/1528-3542.6.4.587 · Cited by 579 · see citing works
Unified protocol for the transdiagnostic treatment of emotional disorders: protocol development and initial outcome data
Ellard, K. K., Fairholme, C. P., Boisseau, C. L., Farchione, T. J., & Barlow, D. H. (2010) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2009.06.002 · Cited by 523 · see citing works
A national survey of practicing psychologists' attitudes toward psychotherapy treatment manuals
Addis, M. E., & Krasnow, A. D. (2000) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.68.2.331 · Cited by 509 · see citing works
A national survey of practicing psychologists' attitudes toward psychotherapy treatment manuals.
Addis, M. E., & Krasnow, A. D. (2000) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.68.2.331 · Cited by 508 · see citing works
The origins of neuroticism
Barlow, D. H., Ellard, K. K., Sauer-Zavala, S., Bullis, J. R., & Carl, J. R. (2014) · Perspectives on Psychological Science · doi:10.1177/1745691614544528 · Cited by 491 · see citing works
Self-citation
A Common Elements Treatment Approach for Adult Mental Health Problems in Low- and Middle-Income Countries
Murray, L. K., Dorsey, S., Haroz, E. E., Lee, C., Alsiary, M. M., Haydary, A., Weiss, W. M., & Bolton, P. A. (2013) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2013.06.005 · Cited by 404 · see citing works
A systematic review and meta-analysis of the Unified Protocol as a transdiagnostic emotion regulation based intervention
Sakiris, N., & Berle, D. (2019) · Clinical Psychology Review · doi:10.1016/j.cpr.2019.101751 · Cited by 369 · see citing works
Balancing fidelity and adaptation in the dissemination of empirically-supported treatments: The promise of transdiagnostic interventions
McHugh, R. K., Murray, H. W., & Barlow, D. H. (2009) · Behaviour Research and Therapy · doi:10.1016/j.brat.2009.07.005 · Cited by 320 · see citing works
Conceptual background, development, and preliminary data from the unified protocol for transdiagnostic treatment of emotional disorders
Wilamowska, Z. A., Thompson-Hollands, J., Fairholme, C. P., Ellard, K. K., Farchione, T. J., & Barlow, D. H. (2010) · Depression and Anxiety · doi:10.1002/da.20735 · Cited by 314 · see citing works
Modularity in the design and application of therapeutic interventions
Chorpita, B. F., Daleiden, E. L., & Weisz, J. R. (2005) · Applied and Preventive Psychology · doi:10.1016/j.appsy.2005.05.002 · Cited by 295 · see citing works
The Four-Function Model of Nonsuicidal Self-Injury
Bentley, K. H., Nock, M. K., & Barlow, D. H. (2014) · Clinical Psychological Science · doi:10.1177/2167702613514563 · Cited by 251 · see citing works
Modular Approach to Therapy for Children with Anxiety, Depression, Trauma, or Conduct Problems (MATCH-ADTC)
Chorpita, B. F., & Weisz, J. R. (2009) · Cited by 242 · see citing works
What is an emotional disorder? A transdiagnostic mechanistic definition with implications for assessment, treatment, and prevention
Bullis, J. R., Boettcher, H., Sauer‐Zavala, S., Farchione, T. J., & Barlow, D. H. (2019) · Clinical Psychology: Science and Practice · doi:10.1111/cpsp.12278 · Cited by 216 · see citing works
Self-citation
Does Cognitive Behavioral Therapy Change the Brain? A Systematic Review of Neuroimaging in Anxiety Disorders
Porto, P. R., Oliveira, L., Mari, J. D. J., Volchan, E., Figueira, I. L. D. V., & Ventura, P. R. (2009) · Journal of Neuropsychiatry · doi:10.1176/jnp.2009.21.2.114 · Cited by 193 · see citing works
Effectiveness of cognitive-behavioral therapy with adult ethnic minority clients: A review.
Horrell, S. C. V. (2008) · Professional Psychology Research and Practice · doi:10.1037/0735-7028.39.2.160 · Cited by 114 · see citing works
What is an emotional disorder? A transdiagnostic mechanistic definition with implications for assessment, treatment, and prevention.
Bullis, J. R., Boettcher, H. T., Sauer-Zavala, S. E., Farchione, T. J., & Barlow, D. H. (2019) · Clinical Psychology Science and Practice · doi:10.1037/h0101755 · Cited by 113 · see citing works
Self-citation
Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents
Ehrenreich, J. T., Kennedy, S. M., Sherman, J. A., Bilek, E. L., Buzzella, B. A., Bennett, S. M., & Barlow, D. H. (2017) · Oxford University Press eBooks · doi:10.1093/med-psych/9780199340989.001.0001 · Cited by 112 · see citing works
Empirical investigations of thought suppression in OCD
Purdon, C. L. (2004) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2004.04.004 · Cited by 107 · see citing works
Anger: The unrecognized emotion in emotional disorders.
Cassiello-Robbins, C. F., & Barlow, D. H. (2016) · Clinical Psychology Science and Practice · doi:10.1111/cpsp.12139 · Cited by 107 · see citing works
Self-citation
Has evidence-based psychosocial treatment for anxiety disorders permeated usual care in community mental health settings?
Wolitzky-Taylor, K., Zimmermann, M., Arch, J. J., De Guzman, E., & Lagomasino, I. (2015) · Behaviour Research and Therapy · doi:10.1016/j.brat.2015.06.010 · Cited by 104 · see citing works
Untitled work
(2011) · Cited by 104 · see citing works
The effects of venlafaxine and cognitive behavioral therapy alone and combined in the treatment of co-morbid alcohol use-anxiety disorders
Ciraulo, D. A., Barlow, D. H., Gulliver, S. B., Farchione, T. J., Morissette, S. B., Kamholz, B. W., Eisenmenger, K., Brown, B., Devine, E. G., Brown, T. A., et al. (2013) · Behaviour Research and Therapy · doi:10.1016/j.brat.2013.08.003 · Cited by 92 · see citing works
Racial and Ethnic Disparity in Major Depressive Disorder
Shao, Z., Richie, W. D., & Bailey, R. K. (2015) · Journal of Racial and Ethnic Health Disparities · doi:10.1007/s40615-015-0188-6 · Cited by 90 · see citing works
Case formulation-driven psychotherapy.
Persons, J. B. (2006) · Clinical Psychology Science and Practice · doi:10.1111/j.1468-2850.2006.00019.x · Cited by 71 · see citing works
Transdiagnostic Treatment Personalization: The Feasibility of Ordering Unified Protocol Modules According to Patient Strengths and Weaknesses
Sauer-Zavala, S., Cassiello-Robbins, C., Ametaj, A. A., Wilner, J. G., & Pagan, D. (2019) · Behavior Modification · doi:10.1177/0145445518774914 · Cited by 67 · cited 6× · see citing works
“Some amount of flexibility has been incorporated as a noted strength in the UP from the start (e.g., tailoring the length of a given module to the needs of the patient; Sauer-Zavala et al., 2019).”
BackgroundInfluentialSelf-citation
The Case for Borderline Personality Disorder as an Emotional Disorder: Implications for Treatment
Sauer-Zavala, S., & Barlow, D. (2014) · Clinical Psychology Science and Practice · doi:10.1111/cpsp.12063 · Cited by 65 · see citing works
Self-citation
Treating ethnic minority adults with anxiety disorders: Current status and future recommendations
Carter, M. M., Mitchell, F. E., & Sbrocco, T. (2012) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2012.02.002 · Cited by 64 · see citing works
Isolating the Unique Effects of the Unified Protocol Treatment Modules Using Single Case Experimental Design
Sauer-Zavala, S. E., Cassiello-Robbins, C. F., Conklin, L. R., Bullis, J. R., Thompson‐Hollands, J., & Kennedy, K. (2016) · Behavior Modification · doi:10.1177/0145445516673827 · Cited by 54 · see citing works
Self-citation
Feasibility of an Emotion Regulation Intervention to Improve Mental Health and Reduce HIV Transmission Risk Behaviors for HIV-Positive Gay and Bisexual Men with Sexual Compulsivity
Parsons, J. T., Rendina, H. J., Moody, R. L., Gurung, S., Starks, T. J., & Pachankis, J. E. (2017) · AIDS and Behavior · doi:10.1007/s10461-016-1533-4 · Cited by 51 · see citing works
Application of a transdiagnostic treatment for emotional disorders to body dysmorphic disorder: A randomized controlled trial
Mohajerin, B., Bakhtiyar, M., Olesnycky, O. S., Dolatshahi, B., & Motabi, F. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.11.058 · Cited by 45 · see citing works
Treating Suicidal Thoughts and Behaviors Within an Emotional Disorders Framework: Acceptability and Feasibility of the Unified Protocol in an Inpatient Setting
Bentley, K. H., Sauer-Zavala, S. E., Cassiello-Robbins, C. F., Conklin, L. R., Vento, S. A., & Homer, D. (2017) · Behavior Modification · doi:10.1177/0145445516689661 · Cited by 44 · see citing works
Self-citation
Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents
Halliday, E. R., & Ehrenreich, J. T. (2020) · Neuromethods · doi:10.1007/978-1-0716-0700-8_13 · Cited by 41 · see citing works
Implementing an evidence-based psychological intervention for suicidal thoughts and behaviors on an inpatient unit: Process, challenges, and initial findings
Bentley, K. H., Sauer-Zavala, S., Stevens, K. T., & Washburn, J. J. (2020) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2018.09.012 · Cited by 24 · cited 2× · see citing works
“In a pre-post implementation study in the United States, the UP was adapted for an inpatient setting to be delivered over 7 days and to incorporate explicit emotion-induction exercises (Bentley et al., 2018).”
BackgroundMethodSelf-citation
Are substance use disorders emotional disorders? Why heterogeneity matters for treatment.
McHugh, R. K., & Goodman, F. R. (2019) · Clinical Psychology Science and Practice · doi:10.1111/cpsp.12286 · Cited by 8 · see citing works

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Andersen, B. L., Lacchetti, C., Ashing, K., Berek, J. S., Berman, B. S., Bolte, S., Dizon, D. S., Given, B., Nekhlyudov, L., Pirl, W., et al. (2023) · Journal of Clinical Oncology · doi:10.1200/jco.23.00293 · Cited by 318 · see citing works
The role of emotion regulation in the characterization, development and treatment of psychopathology
Lincoln, T. M., Schulze, L., & Renneberg, B. (2022) · Nature Reviews Psychology · doi:10.1038/s44159-022-00040-4 · Cited by 234 · see citing works
CBT at the crossroads: the rise of transdiagnostic treatments.
Schaeuffele, C., Schulz, A., Knaevelsrud, C., Renneberg, B., & Boettcher, J. (2021) · International Journal of Cognitive Therapy · doi:10.1007/s41811-020-00095-2 · Cited by 150 · see citing works
Neuroticism and disorders of emotion: a new synthesis
Barlow, D. H., Curreri, A. J., & Woodard, L. S. (2021) · Current Directions in Psychological Science · doi:10.1177/09637214211030253 · Cited by 117 · see citing works
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Rosenthal, M. Z., McMahon, K., Greenleaf, A. S., Cassiello-Robbins, C. F., Guetta, R. E., Trumbull, J., Anand, D., Frazer-Abel, E., & Kelley, L. (2022) · Frontiers in Psychology · doi:10.3389/fpsyg.2022.941898 · Cited by 70 · see citing works
Self-citation
Examining emotional functioning in misophonia: The role of affective instability and difficulties with emotion regulation
Guetta, R. E., Cassiello-Robbins, C., Trumbull, J., Anand, D., & Rosenthal, M. Z. (2022) · PLOS ONE · doi:10.1371/journal.pone.0263230 · Cited by 64 · see citing works
Self-citation
Patterns of childhood maltreatment predict emotion processing and regulation in emerging adulthood
Warmingham, J. M., Duprey, E. B., Handley, E. D., Rogosch, F. A., & Cicchetti, D. (2022) · Development and Psychopathology · doi:10.1017/s0954579422000025 · Cited by 59 · see citing works
Transdiagnostic versus Diagnosis-Specific Group Cognitive Behavioral Therapy for Anxiety Disorders and Depression: A Randomized Controlled Trial
Reinholt, N., Hvenegaard, M., Christensen, A. B., Eskildsen, A., Hjorthøj, C., Poulsen, S., Arendt, M. B., Rosenberg, N. K., Gryesten, J. R., Aharoni, R. N., et al. (2022) · Psychotherapy and Psychosomatics · doi:10.1159/000516380 · Cited by 55 · see citing works
The Royal Canadian Mounted Police (RCMP) study: Protocol for a prospective investigation of mental health risk and resilience factors
Carleton, R. N., Krätzig, G. P., Sauer-Zavala, S., Neary, J. P., Lix, L. M., Fletcher, A. J., Afifi, T. O., Brunet, A., Martin, R., Hamelin, K. S., et al. (2022) · Health Promotion and Chronic Disease Prevention in Canada · doi:10.24095/hpcdp.42.8.02 · Cited by 45 · see citing works
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Scheer, J. R., Clark, K. A., McConocha, E. M., Wang, K., & Pachankis, J. E. (2022) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2022.02.019 · Cited by 45 · see citing works
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The mediating role of emotion regulation in transdiagnostic cognitive behavioural therapy for emotional disorders in primary care: Secondary analyses of the PsicAP randomized controlled trial
Muñoz‐Navarro, R., Medrano, L. A., Limonero, J. T., González‐Blanch, C., Moriana, J. A., Ruiz‐Rodríguez, P., & Vindel, A. C. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.01.029 · Cited by 42 · see citing works
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Rowland, D. P., Casey, L. M., Ganapathy, A., Cassimatis, M., & Clough, B. A. (2021) · Psychosocial Intervention · doi:10.5093/pi2021a8 · Cited by 44 · see citing works
Moderators of LGBQ-affirmative cognitive behavioral therapy: ESTEEM is especially effective among Black and Latino sexual minority men.
Keefe, J. R., Rodriguez-Seijas, C. A., Jackson, S. D., Bränström, R., Harkness, A., Safren, S. A., Hatzenbuehler, M. L., & Pachankis, J. E. (2023) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000799 · Cited by 40 · see citing works
The unified protocol as an internet-based intervention for emotional disorders: Randomized controlled trial
Schaeuffele, C., Homeyer, S. L., Perea, L., Scharf, L., Schulz, A., Knaevelsrud, C., Renneberg, B., & Boettcher, J. (2022) · PLoS ONE · doi:10.1371/journal.pone.0270178 · Cited by 39 · see citing works
Unified protocol vs trauma-focused cognitive behavioral therapy among adolescents with PTSD
Mohajerin, B., Lynn, S. J., & Cassiello-Robbins, C. (2023) · Behavior Therapy · doi:10.1016/j.beth.2023.03.003 · Cited by 35 · see citing works
Self-citation
Unified protocol for the Transdiagnostic treatment of emotional disorders in medical conditions: a systematic review
Osma, J., Martínez-García, L., Quilez-Orden, A., & Peris-Baquero, Ó. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18105077 · Cited by 34 · see citing works
A SMART approach to personalized care: preliminary data on how to select and sequence skills in transdiagnostic CBT
Sauer-Zavala, S. E., Southward, M. W., Stumpp, N. E., Semcho, S., Hood, C. O., Garlock, A., & Urs, A. (2022) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2022.2053571 · Cited by 33 · see citing works
Self-citation
PSICE Project Protocol: Evaluation of the Unified Protocol for Transdiagnostic Treatment for Adolescents with Emotional Symptoms in School Settings
Fonseca‐Pedrero, E., Pérez‐Albéniz, A., Al‐Halabí, S., Lucas‐Molina, B., Sierra, J. O., Díez-Gómez, A., Pérez‐Sáenz, J., Inchausti, F., Valero-García, A. V., García, A. G., et al. (2023) · Clínica y Salud · doi:10.5093/clysa2023a3 · Cited by 32 · see citing works
Transdiagnostic Processes as Mediators of Change in an Internet-Delivered Intervention Based on the Unified Protocol
Schaeuffele, C., Bär, J., Buengener, I., Grafiadeli, R., Heuthaler, E., Strieder, J., Ziehn, P., Knaevelsrud, C., Renneberg, B., & Boettcher, J. (2022) · Cognitive Therapy and Research · doi:10.1007/s10608-021-10272-y · Cited by 24 · see citing works
Dimensions of skill use in the unified protocol: Exploring unique effects on anxiety and depression.
Southward, M. W., & Sauer-Zavala, S. E. (2021) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000701 · Cited by 27 · see citing works
Self-citation
Aversive Reactivity: A Transdiagnostic Functional Bridge Between Neuroticism and Avoidant Behavioral Coping
Semcho, S. A., Southward, M. W., Stumpp, N. E., MacLean, D. L., Hood, C. O., Wolitzky-Taylor, K., & Sauer-Zavala, S. (2023) · Journal of Emotion and Psychopathology · doi:10.55913/joep.v1i1.9 · Cited by 26 · see citing works
Self-citation
Predicting and Moderating the Response to the Unified Protocol: Do Baseline Personality and Affective Profiles Matter?
Osma, J., Péris-Baquero, Ó., Suso‐Ribera, C., Sauer-Zavala, S. E., & Barlow, D. H. (2021) · Cognitive Therapy and Research · doi:10.1007/s10608-021-10208-6 · Cited by 24 · see citing works
Self-citation
Effectiveness of brief group transdiagnostic therapy for emotional disorders in primary care: A randomized controlled trial identifying predictors of outcome
Corpas, J., Moriana, J. A., Martínez, J. F. V., & Gálvez‐Lara, M. (2021) · Psychotherapy Research · doi:10.1080/10503307.2021.1952331 · Cited by 26 · see citing works
Efficacy of the unified protocol for transdiagnostic cognitive-behavioral treatment for depressive and anxiety disorders: a randomized controlled trial
Ito, M., Horikoshi, M., Kato, N., Oe, Y., Fujisato, H., Yamaguchi, K., Nakajima, S., Miyamae, M., Toyota, A., Okumura, Y., et al. (2022) · Psychological Medicine · doi:10.1017/s0033291721005067 · Cited by 24 · see citing works
Brief psychological treatments for emotional disorders in Primary and Specialized Care: A randomized controlled trial
Corpas, J., Moriana, J. A., Martínez, J. F. V., & Gálvez‐Lara, M. (2020) · International Journal of Clinical and Health Psychology · doi:10.1016/j.ijchp.2020.11.002 · Cited by 20 · see citing works
Delivering Transdiagnostic Treatment Over Telehealth During the COVID-19 Pandemic: Application of the Unified Protocol
Cassiello-Robbins, C., Rosenthal, M. Z., & Ammirati, R. J. (2021) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2021.04.007 · Cited by 20 · see citing works
Self-citation
Multidimensional emotional disorders inventory: Reliability and validity in a Spanish clinical sample
Osma, J., Loredo, V. M., Quilez-Orden, A. B., Péris-Baquero, Ó., Ferreres-Galán, V., Prado-Abril, J., Torres-Alfosea, M. Á., & Rosellini, A. J. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.09.140 · Cited by 18 · see citing works
A preliminary evaluation of the unified protocol among trauma-exposed adults with and without PTSD
Hood, C. O., Southward, M. W., Bugher, C., & Sauer-Zavala, S. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182111729 · Cited by 18 · see citing works
Effectiveness of the internet-based Unified Protocol transdiagnostic intervention for the treatment of depression, anxiety and related disorders in a primary care setting: a randomized controlled trial
Timulak, L., Richards, D., Bhandal-Griffin, L., Healy, P., Azevedo, J., Connon, G., Martin, E., Kearney, A., O’Kelly, C., Enrique, A., et al. (2022) · Trials · doi:10.1186/s13063-022-06551-y · Cited by 19 · see citing works
Measurement to Improve Treatment Delivery: A Commentary on the HiTOP Measure Development Project
Sauer-Zavala, S. E. (2021) · Assessment · doi:10.1177/10731911211050952 · Cited by 18 · see citing works
Self-citation
Building Emotional Awareness and Mental Health (BEAM): an open-pilot and feasibility study of a digital mental health and parenting intervention for mothers of infants
Xie, E. B., Freeman, M., Penner‐Goeke, L., Reynolds, K., Lebel, C. A., Giesbrecht, G. F., Rioux, C., MacKinnon, A., Sauer-Zavala, S. E., Roos, L. E., et al. (2023) · Pilot and Feasibility Studies · doi:10.1186/s40814-023-01245-x · Cited by 19 · see citing works
Self-citation
Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in Group Format in Spain: Results of a Noninferiority Randomized Controlled Trial at 15 Months after Treatment Onset
Péris-Baquero, Ó., & Osma, J. (2023) · Depression and Anxiety · doi:10.1155/2023/1981377 · Cited by 20 · see citing works
The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders among Japanese Children: A Pilot Study
Fujisato, H., Kato, N., Namatame, H., Ito, M., Usami, M., Nomura, T., Ninomiya, S., & Horikoshi, M. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.731819 · Cited by 17 · see citing works
Experimental Manipulations to Test Theory-Driven Mechanisms of Cognitive Behavior Therapy
Southward, M. W., & Sauer-Zavala, S. E. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.603009 · Cited by 17 · see citing works
Self-citation
RESILIENCE, COPING, AND THE COVID-19 PANDEMIC ACROSS THE GLOBE – AN UPDATE: WHAT HAVE WE LEARNED?
Polizzi, C. P., McDonald, C. W., Sleight, F. G., & Lynn, S. J. (2023) · PubMed Central · doi:10.36131/cnfioritieditore20230411 · Cited by 14 · see citing works
“…intervention that affords the opportunity to promote regulatory flexibility by integrating other coping skills, such as acceptance and self-compassion, which may help bolster resilience during the pandemic based on situational demands and individual needs (Cassiello-Robbins et al., 2020).”
Cognitive behavioural therapy and third-wave approaches for anxiety and related disorders in older people
Hendriks, G., Janssen, N., Robertson, L., van Balkom, A. J. L. M., van Zelst, W. H., Wolfe, S., Voshaar, R. C. O., & Uphoff, E. (2024) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007674.pub3 · Cited by 20 · see citing works
Developing a smartphone App based on the Unified Protocol for the transdiagnostic treatment of emotional disorders: A qualitative analysis of users and professionals' perspectives
Osma, J., Martínez‐García, L., Prado-Abril, J., Péris-Baquero, Ó., & González‐Pérez, A. (2022) · Internet Interventions · doi:10.1016/j.invent.2022.100577 · Cited by 17 · see citing works
A pilot randomized effectiveness trial of the unified protocol in trauma‐exposed veterans
Gutner, C. A., Song, J., Canale, C. A., Suvak, M. K., Litwack, S. D., Niles, B. L., & Stirman, S. W. (2022) · Depression and Anxiety · doi:10.1002/da.23288 · Cited by 15 · see citing works
The unified protocol for transdiagnostic treatment of emotional disorders for misophonia: a pilot trial exploring acceptability and efficacy
McMahon, K., Cassiello-Robbins, C. F., Greenleaf, A. S., Guetta, R. E., Frazer-Abel, E., Kelley, L., & Rosenthal, M. Z. (2024) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1294571 · Cited by 15 · see citing works
Self-citation
Efficacy of a transdiagnostic internet-based program for adolescents with emotional disorders: A randomized controlled trial
Espinosa, V., Valiente, R. M., García-Escalera, J., Chorot, P., Arnáez, S., Schmitt, J. C., & Sandín, B. (2024) · Behaviour Research and Therapy · doi:10.1016/j.brat.2024.104560 · Cited by 15 · see citing works
Can We Boost Treatment Adherence to an Online Transdiagnostic Intervention by Adding Self-Enhancement Strategies? Results From a Randomized Controlled Non-inferiority Trial
Isbăşoiu, A. B., Tulbure, B. T., Rusu, A., & Sava, F. A. (2021) · Frontiers in Psychology · doi:10.3389/fpsyg.2021.752249 · Cited by 14 · see citing works
Assessing the impact of the Royal Canadian Mounted Police (RCMP) protocol and Emotional Resilience Skills Training (ERST) among diverse public safety personnel
Carleton, R. N., McCarron, M. C. E., Krätzig, G. P., Sauer-Zavala, S. E., Neary, J. P., Lix, L. M., Fletcher, A. J., Camp, R. D., Shields, R. E., Jamshidi, L., et al. (2022) · BMC Psychology · doi:10.1186/s40359-022-00989-0 · Cited by 14 · see citing works
Self-citation
Emotion dysregulation and neuroticism as moderators of group Unified Protocol effectiveness outcomes for treating emotional disorders
Péris-Baquero, Ó., Moreno-Pérez, J. D., Haro, M. V. N., Díaz‐García, A., & Osma, J. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.03.079 · Cited by 15 · see citing works
Assessing Theories of State and Trait Change in Neuroticism and Symptom Improvement in the Unified ProtocolPreprint
Stumpp, N. E., Southward, M. W., & Sauer-Zavala, S. E. (2023) · Behavior Therapy · doi:10.1016/j.beth.2023.05.005 · Cited by 13 · see citing works
Self-citation
The Unified Protocol for Transdiagnostic Treatment of Emotional Disorders compared with diagnosis-specific protocols for anxiety disorders: A three-year follow-up
Bullis, J. R., Eustis, E. H., Curreri, A. J., Cardona, N. D., Woods, B. K., Rosellini, A. J., Barlow, D. H., & Farchione, T. J. (2023) · Journal of Mood and Anxiety Disorders · doi:10.1016/j.xjmad.2023.100024 · Cited by 11 · see citing works
Mental health disorder symptom changes among public safety personnel after emotional resilience skills training
Carleton, R. N., Sauer-Zavala, S. E., Teckchandani, T. A., Maguire, K. Q., Jamshidi, L., Shields, R. E., Afifi, T. O., Nisbet, J., Andrews, K. L., Stewart, S. H., et al. (2025) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2025.152580 · Cited by 16 · see citing works
Self-citation
Implementation, efficacy and cost effectiveness of the unified protocol in a blended format for the transdiagnostic treatment of emotional disorders: a study protocol for a multicentre, randomised, superiority controlled trial in the Spanish National Health System
Osma, J., Martínez‐García, L., Péris-Baquero, Ó., Haro, M. V. N., González‐Pérez, A., & Suso‐Ribera, C. (2021) · BMJ Open · doi:10.1136/bmjopen-2021-054286 · Cited by 13 · see citing works
Associations between improvements in aversive reactions to negative emotions and increased quality of life in the unified protocol
Elhusseini, S. A., Cravens, L. E., Southward, M. W., & Sauer-Zavala, S. (2022) · Journal of Behavioral and Cognitive Therapy · doi:10.1016/j.jbct.2021.12.001 · Cited by 7 · see citing works
Self-citation
Aplicación del protocolo unificado para el tratamiento transdiagnóstico de los trastornos emocionales en pacientes post-cirugía bariátrica: estudio de efectividad y viabilidad en formato grupal
Ferreres-Galán, V., Quilez-Orden, A. B., & Osma, J. (2022) · Anales de Psicología · doi:10.6018/analesps.482301 · Cited by 11 · see citing works
Brief psychological therapies for emotional disorders in primary care: A systematic review and meta-analysis.
Corpas, J., Moriana, J. A., Martínez, J. F. V., & Gálvez‐Lara, M. (2021) · Clinical Psychology Science and Practice · doi:10.1037/cps0000009 · Cited by 10 · see citing works
Network Structure of Transdiagnostic Dimensions of Emotional Disorders in Adolescents With Subthreshold Anxiety and Depression: Links With Psychopathology and Socio‐Emotional Adjustment
Ródenas‐Perea, G., Pérez‐Esteban, A., Pérez‐Albéniz, A., Al‐Halabí, S., & Fonseca‐Pedrero, E. (2024) · Early Intervention in Psychiatry · doi:10.1111/eip.13636 · Cited by 10 · see citing works
Application of the unified protocol for transdiagnostic treatment of emotional disorders among homeless women: A feasibility study.
Marín‐Martín, C., Guillén, A. I., Rodriguez‐Moreno, S., Diéguez, S., Panadero, S., & Farchione, T. J. (2021) · Psychotherapy · doi:10.1037/pst0000357 · Cited by 10 · see citing works
Building Emotional Awareness and Mental Health (BEAM): study protocol for a phase III randomized controlled trial of the BEAM app-based program for mothers of children 18–36 months
Xie, E. B., Simpson, K. M., Reynolds, K., Giuliano, R. J., Protudjer, J. L. P., Söderström, M., Sauer-Zavala, S. E., Giesbrecht, G. F., Lebel, C. A., MacKinnon, A., et al. (2022) · Trials · doi:10.1186/s13063-022-06512-5 · Cited by 9 · see citing works
Self-citation
Inteligencia emocional y regulación emocional: factores transdiagnósticos claves en problemas emocionales, trastornos de ansiedad y depresión
Antuña‐Camblor, C., Vindel, A. C., Carballo, M. E., Juarros‐Basterretxea, J., & Rodríguez‐Díaz, F. J. (2023) · Escritos de Psicología / Psychological Writings · doi:10.24310/espsiescpsi.v16i1.14771 · Cited by 8 · see citing works
A qualitative study on the implementation of a transdiagnostic cognitive behavioral therapy for children in a child welfare residential treatment program
Dimitropoulos, G., Lindenbach, D., Anderson, A., Rowbotham, M., Wang, E., Heintz, M., Ehrenreich, J. T., & Arnold, P. D. (2023) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2023.106487 · Cited by 9 · see citing works
Guiding future research on psychological interventions in people with COVID-19 and post COVID syndrome and comorbid emotional disorders based on a systematic review
Martínez‐Borba, V., Martínez‐García, L., Péris-Baquero, Ó., Osma, J., & Corral-Beamonte, E. D. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1305463 · Cited by 8 · see citing works
The effects of the Unified Protocol and Unified Protocol skills on loneliness in the COVID‐19 pandemic
Southward, M. W., Terrill, D. R., & Sauer‐Zavala, S. (2022) · Depression and Anxiety · doi:10.1002/da.23297 · Cited by 8 · see citing works
Self-citation
The assessment of transdiagnostic dimensions of emotional disorders: Validation of the Multidimensional Emotional Disorders Inventory (MEDI) in adolescents with subthreshold anxiety and depression
Pérez‐Esteban, A., Díez-Gómez, A., Pérez‐Albéniz, A., Al‐Halabí, S., Lucas‐Molina, B., Debbané, M., & Fonseca‐Pedrero, E. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.04.081 · Cited by 7 · see citing works
Together and beyond: A systematic review on characteristics and efficacy of transdiagnostic psychotherapeutic group-based interventions for children and adolescents
Bähr, C., Phan, D., Murawska, N., Gerber, J., Jordan, A., Hoffmann, K., & Calvano, C. (2025) · Clinical Psychology Review · doi:10.1016/j.cpr.2025.102642 · Cited by 8 · see citing works
Targeting emotional regulation using an Internet‐delivered psychological intervention for cancer survivors: A randomized controlled trial
Smith, I. S., Bind, M., Weihs, K. L., Bei, B., & Wiley, J. F. (2023) · British Journal of Health Psychology · doi:10.1111/bjhp.12679 · Cited by 9 · see citing works
Efficacy of the unified protocol for transdiagnostic treatment of comorbid emotional disorders in patients with ultra high risk for psychosis: Results of a randomized controlled trial
Peláez, T., López‐Carrilero, R., Espinosa, V., Balsells, S., Ochoa, S., & Osma, J. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.09.036 · Cited by 9 · see citing works
Exploring the Optimal Factor Structure of the Five Facet Mindfulness Questionnaire: Associations Between Mindfulness Facets and Dimensions of Psychopathology
Diehl, J. M., Rodriguez-Seijas, C. A., Thompson, J. S., Dalrymple, K. L., Chelminski, I., & Zimmerman, M. (2021) · Journal of Personality Assessment · doi:10.1080/00223891.2021.1998080 · Cited by 9 · see citing works
The importance of idiographic and functionally analytic strategies in the unified protocol for transdiagnostic treatment of emotional disorders
Barlow, D. H., & Eustis, E. H. (2022) · Journal of Contextual Behavioral Science · doi:10.1016/j.jcbs.2022.05.001 · Cited by 7 · see citing works
Are central eating disorder network symptoms sensitive to item selection and sample? Implications for conceptualization of eating disorder psychopathology from a network perspective.
Cusack, C. E., Vanzhula, I. A., Sandoval-Araujo, L. E., Pennesi, J., Kelley, S. W., & Levinson, C. A. (2023) · Journal of Psychopathology and Clinical Science · doi:10.1037/abn0000865 · Cited by 9 · see citing works
Treating co-morbid insomnia and social anxiety disorder with sequential CBT protocols: a single-case experimental study
Wallsten, D., Norell‐Clarke, A., Alfonsson, S., Gryphon, D., Eriksson, H., & Tillfors, M. (2021) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s1352465821000278 · Cited by 7 · see citing works
Do Unified Protocol modules exert general or unique effects on anxiety, depression, and transdiagnostic targets?
Southward, M. W., Lane, S. P., Shroyer, S. E., & Sauer-Zavala, S. (2023) · Journal of Mood & Anxiety Disorders · doi:10.1016/j.xjmad.2023.100022 · Cited by 6 · see citing works
Self-citation
Mechanism engagement as a potential evidence-based approach to personalized treatment termination
Sauer-Zavala, S. E., Southward, M. W., Terrill, D. R., Semcho, S., & Stumpp, N. E. (2023) · Psychotherapy Research · doi:10.1080/10503307.2023.2168574 · Cited by 6 · see citing works
Self-citation
Acceptability of and intention to use the Unified Protocol delivered in group format in the Spanish Public Health System
Péris-Baquero, Ó., Osma, J., Gil‐Lacruz, M., & Martínez‐García, L. (2021) · Journal of Evaluation in Clinical Practice · doi:10.1111/jep.13546 · Cited by 6 · see citing works
The Unified Protocol as an Internet-based Intervention for Emotional Disorders: Randomized Controlled Trial
Schaeuffele, C., Homeyer, S. L., Perea, L., Scharf, L., Schulz, A., Knaevelsrud, C., Renneberg, B., & Boettcher, J. (2020) · doi:10.31234/osf.io/528tw · Cited by 9 · see citing works
Feasibility and Acceptability of Implementing a Transdiagnostic Cognitive Behavioral Therapy for Children Impacted by Trauma Within a Residential Treatment Facility
Lindenbach, D., Anderson, A., Wang, E., Heintz, M., Rowbotham, M., Ehrenreich, J. T., Arnold, P. D., & Dimitropoulos, G. (2024) · Child & Youth Services · doi:10.1080/0145935x.2024.2340550 · Cited by 5 · see citing works
RegulEm, an unified protocol based-app for the treatment of emotional disorders: a parallel mixed methods usability and quality study
Martínez‐García, L., Fadrique‐Jiménez, A., -Galán, V.-F., Flors, C. R., & Osma, J. (2024) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-024-02679-w · Cited by 6 · see citing works
Evidence of a transdiagnostic cognitive-factor for the assessment of depression and anxiety disorders in primary care patients
Muñoz‐Navarro, R., Garrido, L. E., Esteller-Collado, G., Carpallo-González, M., Jurado-González, F. J., Gálvez‐Lara, M., Prieto-Vila, M., González‐Blanch, C., Ruiz‐Rodríguez, P., Moriana, J. A., et al. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.119821 · Cited by 6 · see citing works
Optimizing Outcomes in Psychotherapy for Anxiety Disorders Using Smartphone-Based and Passive Sensing Features: Protocol for a Randomized Controlled Trial
Müller-Bardorff, M., Schulz, A., Paersch, C., Recher, D., Schlup, B., Seifritz, E., Kolassa, I., Kowatsch, T., Fisher, A. J., Galatzer‐Levy, I. R., et al. (2022) · JMIR Research Protocols · doi:10.2196/42547 · Cited by 8 · see citing works
Analyses of prediction, moderation, and mediation of a transdiagnostic, indicated preventive intervention (PROCARE-I) for adolescents at high risk of emotional problems
Jimenez-Vazquez, D., López, L. J. G., Piqueras, J. A., Muela-Martínez, J. A., Fernández, L. E., Vivas-Fernández, M., & Díaz-Castela, M. D. M. (2024) · Evidence-Based Practice in Child and Adolescent Mental Health · doi:10.1080/23794925.2024.2384088 · Cited by 5 · see citing works
Development and Pilot Testing of an Internet-Based Version of the Unified Protocol That Targets Positive Affect Regulation: A Treatment Development Report
Eustis, E. H., Nauphal, M., Jaso, B. A., Spencer-Laitt, D., Woodard, L. S., Farchione, T. J., & Barlow, D. H. (2024) · Cognitive and Behavioral Practice · doi:10.1016/j.cbpra.2024.07.003 · Cited by 5 · see citing works
The unified protocol: patient and therapist perspectives on the utility of the group manual
Christensen, A. B., Gryesten, J. R., Kokholm, J., Vislie, K., Reinholt, N., Dichmann, K., Poulsen, S., & Arnfred, S. (2022) · Clinical Psychologist · doi:10.1080/13284207.2022.2061340 · Cited by 5 · see citing works
Effectiveness of online integrative trans-diagnostic treatment on internet addiction and high-risk behaviors in female adolescents with borderline personality disorder with comorbid depressive disorder
Mohamadpour, F., & Mohammadi, N. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1291579 · Cited by 5 · see citing works
Unified Protocols for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents
Roberts, A. G., Taylor-Cavelier, S. J., Díaz, K. I., Codd, E. L., Hawks, J. L., & Kennedy, S. M. (2025) · Advances in Psychiatry and Behavioral Health · doi:10.1016/j.ypsc.2025.02.004 · Cited by 5 · see citing works
Study on the use, acceptability and implementation of the Unified Protocol in general health psychologists in Spain
Péris-Baquero, Ó., Osma, J., & Martínez-Segura, V. (2022) · Anales de Psicología · doi:10.6018/analesps.484101 · Cited by 4 · see citing works
Translating the Transdiagnostic: Aligning Assessment Practices With Research Advances
Vize, C. E., & Wright, A. G. C. (2023) · Assessment · doi:10.1177/10731911231194996 · Cited by 6 · see citing works
Treating perfectionism via the Internet: a randomized controlled trial comparing cognitive behavior therapy to unified protocol
Rozental, A., Shafran, R., Johansson, F., Forsström, D., Jovicic, F., Gelberg, O., Molin, K., Carlbring, P., Andersson, G., & Buhrman, M. (2024) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2024.2327339 · Cited by 4 · see citing works
Cognitive processes associated with emotional disorders: implications for efficient psychological treatments
Corpas, J., Moriana, J. A., Martínez, J. F. V., & Gálvez‐Lara, M. (2021) · Journal of Mental Health · doi:10.1080/09638237.2021.1922651 · Cited by 4 · see citing works
A preliminary examination of unified protocol for transdiagnostic treatment of emotional disorders in patients with panic disorder: a single-case experimental design in Iran
Zemestani, M., Davoudi, F., Farhadi, A., & Gallagher, M. W. (2021) · Anxiety Stress & Coping · doi:10.1080/10615806.2021.1990269 · Cited by 4 · see citing works
Response and ongoing skills use following a single-session virtual cognitive behavioral workshop for graduate students
Bernstein, E. E., LeBlanc, N. J., & McNally, R. J. (2022) · Journal of American College Health · doi:10.1080/07448481.2022.2098036 · Cited by 5 · see citing works
Unified Protocol Versus Self‐Acceptance Group Therapy for Emotional Disorders in People With Severe Shame
Mohajerin, B., & Howard, R. (2024) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.3022 · Cited by 3 · see citing works
Predictors and Moderators of Panic Disorder: Cognitive Behavioral Therapy vs. Acceptance and Commitment Therapy
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Authors: Cassiello-Robbins, C., Southward, M. W., Tirpak, J. W., & Sauer-Zavala, S.
Affiliations: Duke Medical Center (US)
University of Kentucky (US)
Corresponding author: Cassiello-Robbins, Clair
ORCID: Southward, Matthew W.
Sauer-Zavala, Shannon
Venue: Clinical Psychology Review
Publisher: Elsevier BV
Published: 2020-06
Volume: 78
Pages: 101852
ISSN: 0272-7358 (ISSN-L)
DOI: 10.1016/j.cpr.2020.101852
OpenAlex: W3018886528
Cited by: 179
References: 59
Citations by year: 2026: 21 · 2025: 26 · 2024: 30 · 2023: 40 · 2022: 32 · 2021: 24 · 2020: 5
FWCI: 3.69
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Clinical Psychology Review (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
Keywords: Unified Protocol, transdiagnostic treatment, emotional disorders, adults, dissemination, intervention adaptability, anxiety disorders, depression, bipolar disorder, trauma, substance use disorders, eating disorders, borderline personality disorder, insomnia, non-suicidal self-injury, sexual minority stress, treatment setting
MeSH terms: Affective Symptoms, Mental Disorders, Clinical Protocols, Humans, Outcome and Process Assessment, Health Care, Psychotherapy, Evidence-Based Practice

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A systematic review of unified protocol applications with adult populations: facilitating widespread dissemination via adaptability

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