Sleep and suicide: A systematic review and meta-analysis of longitudinal studies
Open accessAbstract
The current review provides a quantitative synthesis of the empirical literature on sleep disturbance as a risk factor for suicidal thoughts and behaviors (STBs). A systematic search of PsycINFO, MEDLINE, and the references of prior reviews resulted in 41 eligible studies included in this meta-analysis. Sleep disturbance, including insomnia, prospectively predicted STBs, yielding small-to-medium to medium effect sizes for these associations. Complicating interpretation of these findings however, is that few studies of suicidal ideation and suicide attempts, as well as none of suicide deaths, assessed short-term risk (i.e., employed follow-up assessments of under a month). Such studies are needed to evaluate current conceptualizations of sleep dysregulation as being involved in acute risk for suicidal behavior. This want of short-term risk studies also suggests that current clinical recommendations to monitor sleep as a potential warning sign of suicide risk has a relatively modest empirical basis, being largely driven by cross-sectional or retrospective research. The current review ends with recommendations for generating future research on short-term risk and greater differentiation between acute and chronic aspects of sleep disturbance, and by providing a model of how sleep disturbance may confer risk for STBs through neuroinflammatory and stress processes and associated impairments in executive control.
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Claims the paper makes
22 of 62 cited sources checked · 17 supported · 0 flagged · accuracy not yet measured
- Premisecitation
Four of the prior systematic reviews were meta-analyses.
“Although four of these prior systematic reviews were meta-analyses (Chiu et al., 2018; Liu, Tu, et al., 2019; Malik et al., 2014; Pigeon et al., 2012)”
Quote in the paperSubstantial claim1 of 3 sources checked - Premisecitation
Risk factors found in non-clinical or community samples may generalize poorly to clinical or high-risk individuals seen by mental health providers.
“Furthermore, risk factors identified in non-clinical or community samples may be of limited generalizability to the clinical or high-risk individuals more often encountered by mental health care providers (for examples, see King, Berona, Czyz, Horwitz, & Gipson, 2015; Yen et al., 2013; for a related discussion, see Millman, Gold, Mittal, & Schiffman, 2019).”
Quote in the paperNot a substantial claim3 of 3 sources checked- cites King, Berona, Czyz, Horwitz, & Gipson, 2015 source
The Methods describe a study of adolescents who screened positive for suicide risk in a general emergency department, so the paper serves as an example of research in a high-risk care-seeking group. The Discussion questions whether its own findings generalize to adolescents in other EDs, but it does not assess whether risk factors identified in non-clinical or community samples generalize poorly to clinical or high-risk individuals. Page numbers were not available in our copy. (LLM, conf=0.84)
Experimental — accuracy not yet measured - cites Yen et al., 2013 sourceExperimental — accuracy not yet measured
- cites Millman, Gold, Mittal, & Schiffman, 2019 source
- Premisereasoning
Longer follow-up periods are most often used to maximize the number of suicidal thoughts and behaviors available for analysis.
“an obstacle most often addressed by including longer follow-up periods so as to maximize the number of STBs available for analysis (Bredemeier & Miller, 2015; Franklin et al., 2017; Wenzel et al., 2011), thus the pattern found in the current review of median follow-up lengths increasing substantially with severity of STB.”
Quote in the paperSubstantial claim1 of 3 sources checked- cites Bredemeier & Miller, 2015 source
The Discussion section (‘Alternative study designs’; page not provided) identifies extending follow-up as a way to address the low incidence of suicidality in prospective studies. It does not say longer follow-ups are the most often used approach or report how frequently researchers use them. (LLM, conf=0.84)
Experimental — accuracy not yet measured - cites Franklin et al., 2017 source
- cites Wenzel et al., 2011 source
- Rests on an assumption: Suicide attempts and deaths are low-base-rate events, with attempts relatively infrequent in the general population and deaths considerably rarer.
- Premisereasoning
Achieving sufficient statistical power for meaningful analysis is a methodological challenge in suicide research.
“This introduces the not insignificant methodological challenge in the study of suicide of achieving sufficient statistical power for meaningful analysis (American Psychiatric Association, 2004; Borges et al., 2006; Klonsky et al., 2016; Nock et al., 2008; Prinstein, 2008; Prinstein et al., 2008), an obstacle most often addressed by including longer follow-up periods so as to maximize the number of”
Quote in the paperSubstantial claim1 of 3 sources checked- cites American Psychiatric Association, 2004
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Borges et al., 2006 source
- cites Klonsky et al., 2016 source
- Rests on an assumption: Suicide attempts and deaths are low-base-rate events, with attempts relatively infrequent in the general population and deaths considerably rarer.
- Premisecitation
There is some experimental evidence that ketamine may reduce suicidality through normalizing sleep.
“Even more implicative of a possible causal role for sleep disturbance in suicide risk, again in terms of suicidal ideation, there is some experimental evidence that ketamine may exert an anti-suicidal effect through its effect on normalizing sleep (Vande Voort et al., 2017).”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Vande Voort et al., 2017 source
- Premisecitation
Heightened expression of several pro-inflammatory cytokines, such as IL-6, has been found in the prefrontal cortex of suicide decedents.
“More directly supportive of this hypothesis, heightened expression of several pro-inflammatory cytokines (e.g., IL-6) has been found in the prefrontal cortex of suicide decedents (Pandey et al., 2012; also see Lutz, Mechawar, & Turecki, 2017).”
Quote in the paperSubstantial claim1 of 2 sources checked - Premisecitation
Disrupted sleep may activate inflammatory processes, such as elevations in IL-6 and CRP, according to observational and experimental studies.
“That disrupted sleep may lead to activation of inflammatory processes (e.g., elevations in interleukin-6 [IL-6] and C-reactive protein [CRP]) has received substantial support from observational and experimental studies (Irwin et al., 2016; Irwin & Piber, 2018).”
Quote in the paperSubstantial claim1 of 2 sources checked- cites Irwin et al., 2016 source
The Results and Discussion report that sleep disturbance was associated with higher circulating IL-6 and CRP, supporting the observational part of the claim. The Discussion says experimental sleep loss activated cellular inflammatory pathways but did not raise circulating inflammatory markers; thus experimental evidence does not support the cited example of elevated IL-6 and CRP. (LLM, conf=0.88)
Experimental — accuracy not yet measured - cites Irwin & Piber, 2018 source
- Premisecitation
Peripheral cytokines may produce neuroinflammatory responses through pathways including the vagus nerve and microglial activation.
“Indeed, peripheral cytokines may produce neuroinflammatory responses through several pathways and processes, including communicating through the vagus nerve and microglial activation (Debnath et al., 2011), and abnormal elevations in these pro-inflammatory cytokines have been identified in the cerebrospinal fluid and post-mortem brain samples of suicidal individuals (Black & Miller, 2015).”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Debnath et al., 2011 source
- Premisecitation
Different facets of executive control have been associated with suicide risk.
“Finally, different facets of executive control have, in turn, been associated with suicide risk (Liu et al., 2017; Miranda et al., 2012).”
Quote in the paperSubstantial claim2 of 2 sources checked - Premisecitation
A sleep-deprivation study found that it led adolescents to show negative affect, conflict, withdrawal, and dominance during a social conflict task.
“In line with this possibility, a study using a sleep-deprivation paradigm found it to lead adolescents to behave in ways characterized by negative affect, conflict, withdrawal, and dominance during a social conflict task (McMakin et al., 2016).”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites McMakin et al., 2016 source
- Premisecitation
Executive functions are the cognitive systems first and most severely impaired by sleep deprivation.
“Also relevant are findings that executive functions are the cognitive systems to be first, and most severely, impaired by sleep deprivation (Diamond, 2013).”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Diamond, 2013 source
- Findingown data
The pooled effect size for sleep disturbance predicting suicide attempts was small-to-medium (d = .39, 95% CI .16-.63).
“In the case of sleep disturbance prospectively predicting suicide attempts, the pooled effect size was small-to-medium (d = .39, 95% CI = .16 – .63)”
Quote in the paperSubstantial claim - Findingown data
The pooled effect size for sleep disturbance predicting suicidal ideation was small-to-medium (d = .41, 95% CI .30-.51).
“The pooled effect size for sleep disturbances in relation to suicidal ideation was small-to-medium (d = .41, 95% CI = .30 – .51)”
Quote in the paperSubstantial claim - Findingown data
The pooled effect size for sleep disturbance predicting suicide deaths was medium (d = .50, 95% CI .14-.85).
“As for the relation between sleep disturbance and suicide deaths, a medium pooled effect size was obtained (d = .50, 95% CI = .14 – .85)”
Quote in the paperSubstantial claim - Findingown data
This multivariate model accounted for 45% of the variance in the effect sizes for sleep disturbance in relation to future suicidal ideation.
“This multivariate model accounted for 45% of the variance in the effect sizes for sleep disturbance in relation to future suicidal ideation.”
Quote in the paperNot a substantial claim - Findingown data
The strength of the association between sleep disturbance and suicide deaths varied as a function of the sleep measure used, with larger effects evident for questionnaire measures (d = .36, 95% CI .28-.44) than interview-based ones (d = .18, 95% CI .05-.30).
“Finally, the strength of the association between sleep disturbance and suicide deaths varied as a function of the sleep measure used, with larger effects evident for questionnaire measures (d = .36, 95% CI = .28 – .44) than interview-based ones (d = .18, 95% CI = .05 – .30).”
Quote in the paperSubstantial claim - Findingown data
Only one effect was available for nightmares and suicide deaths, d = .50, 95% CI .18 to .83.
“Only one effect was available for the relation between nightmares and suicide deaths (d = .50, 95% CI = .18 – .83).”
Quote in the paperNot a substantial claim - Findingown data
A larger weighted effect was found for questionnaire measures of sleep disturbance (d = .43, 95% CI .33-.52) than for interview-based measures (d = .10, 95% CI −.11-.32) in relation to prospective suicidal ideation.
“a larger weighted effect was found for questionnaire measures of sleep disturbance (d = .43, 95% CI = .33 – .52) than for interview-based measures (d = .10, 95% CI = −.11 – .32)”
Quote in the paperNot a substantial claim - Findingown data
Only one effect was available for hypersomnia and suicide deaths, d = .84, 95% CI .25 to 1.42.
“There was only one effect for hypersomnia and suicide deaths (d = .84, 95% CI = .25 – 1.42).”
Quote in the paperNot a substantial claim - Findingown data
For insomnia and later suicidal ideation, the pooled effect was small-to-medium, d = .45, 95% CI .32 to .58, with follow-ups from three days to seven years and a median of 10.5 months.
“A small-to-medium pooled effect was observed for insomnia in relation to suicidal ideation (d = .45, 95% CI = .32 – .58), with follow-ups ranging from three days to seven years (median follow-up length = 10.5 months).”
Quote in the paperSubstantial claim - Findingown data
A larger pooled effect was obtained for study follow-up assessments of a month or briefer (d = .61, 95% CI −.49-.73) than for follow-up lengths of over a month (d = .34, 95% CI −.23-.44) in relation to suicidal ideation.
“A larger pooled effect was obtained for study follow-up assessments of a month or briefer (d = .61, 95% CI = −.49 – .73) than for follow-up lengths of over a month (d = .34, 95% CI = −.23 – .44).”
Quote in the paperNot a substantial claim - Findingreasoning
Interview-based measures of sleep disturbance yielded smaller effects than self-report measures.
“We also found that interview-based measures of sleep disturbance produced smaller effects than did self-report measures of this construct.”
Quote in the paperSubstantial claim - Findingown data
For nightmares and later suicide attempts, the weighted effect was medium, d = .64, 95% CI .43 to .84.
“In the case of nightmares, the current evidence, although preliminary, was stronger for an association with STBs, with a small-to-medium weighted effect for prospective suicidal ideation (d = .40, 95% CI = .06 – .74) and medium weighted effect for prospective suicide attempts (d = .64, 95% CI = .43 – .84).”
Quote in the paperSubstantial claim - Findingown data
For nightmares and later suicidal ideation, the weighted effect was small-to-medium, d = .40, 95% CI .06 to .74.
“In the case of nightmares, the current evidence, although preliminary, was stronger for an association with STBs, with a small-to-medium weighted effect for prospective suicidal ideation (d = .40, 95% CI = .06 – .74) and medium weighted effect for prospective suicide attempts (d = .64, 95% CI = .43 – .84).”
Quote in the paperSubstantial claim - Findingown data
After trim-and-fill correction for publication bias, the pooled effect linking overall sleep disturbance to later suicidal ideation stayed small-to-medium, d = .35, 95% CI .25 to .45.
“After adjusting for publication bias in the trim-and-fill analysis, the weighted effect remained small-to-medium (d = .35, 95% CI = .25 – .45).”
Quote in the paperSubstantial claim - Findingown data
In a meta-regression including sleep measure type and length of follow-up assessment, only length of follow-up remained a significant moderator of the strength of the association between sleep disturbance and subsequent suicidal ideation (b = .20, p = .03) when follow-up lengths of under a year versus a year or longer were considered.
“In a meta-regression analysis including sleep measure type and length of follow-up assessment, only the latter variable remained a significant moderator of the strength of the association between sleep disturbance and subsequent suicidal ideation (b = .20, p =. 03) when follow-up lengths of under a year versus a year or longer were considered.”
Quote in the paperSubstantial claim - Findingown data
A larger weighted effect was found for study follow-up assessments of under a year (d = .54, 95% CI .39-.68) than for follow-up assessments of at least a year (d = .27, 95% CI .15-.39) in relation to prospective suicidal ideation.
“as well as for study follow-up assessments of under a year (d = .54, 95% CI = .39 – .68) than for follow-up assessments of at least a year (d = .27, 95% CI = .15 – .39).”
Quote in the paperSubstantial claim - Findingown data
For insomnia and later suicide attempts, the weighted effect was small-to-medium, d = .38, 95% CI .15 to .61, with follow-ups from three days to 36 years and a median of two years.
“With regards to the association between insomnia and subsequent suicide attempts, a small-to-medium weighted effect was also found (d = .38, 95% CI = .15 – .61), with follow-ups ranging from three days to 36 years (median follow-up length = two years).”
Quote in the paperSubstantial claim - Findingown data
Follow-up length did not significantly moderate the association between overall sleep disturbance and suicide attempts.
“Although follow-up length did not also significantly moderate the strength of the association between overall sleep disturbance and suicide attempts, only four of the included studies featured follow-ups of under a year, in contrast to 13 in the case of suicidal ideation.”
Quote in the paperNot a substantial claim - Findingnone given
The included studies, with few exceptions, assessed sleep at one time-point in isolation as a predictor of later suicidal thoughts and behaviors.
“Second, the studies included in the current review, with few exceptions (e.g., Littlewood et al., 2019), focused on evaluating whether sleep assessed at one time-point in isolation predicts STBs at a subsequent time-point.”
Quote in the paperSubstantial claim - Premisenone given
Most studies included in these prior meta-analyses employed cross-sectional designs or analyses.
“most of the studies included in these meta-analyses employed cross-sectional designs or analyses.”
Quote in the paperSubstantial claim - Premisecitation
Six systematic reviews have provided evidence that a range of sleep disturbances are correlates of suicidal thoughts and behaviors.
“To date, there have been six systematic reviews (Bernert et al., 2015; Chiu et al., 2018; Kearns et al., 2020; Liu, Tu, et al., 2019; Malik et al., 2014; Pigeon et al., 2012), all providing evidence suggesting that a range of sleep disturbances are indeed correlates of STBs.”
Quote in the paperSubstantial claim0 of 3 sources checked - Interpretationreasoning
Current clinical recommendations to monitor sleep as a potential warning sign of suicide risk have a relatively modest empirical basis, being largely driven by cross-sectional or retrospective research.
“This want of short-term risk studies also suggests that current clinical recommendations to monitor sleep as a potential warning sign of suicide risk has a relatively modest empirical basis, being largely driven by cross-sectional or retrospective research.”
Quote in the paperSubstantial claim - Premisecitation
A longitudinal design is necessary to assess whether a variable is a risk factor, because it establishes temporal precedence.
“A longitudinal design is necessary to assess the extent to which a variable may be considered a risk factor, temporally preceding the outcome of interest (Kraemer et al., 1997).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Kraemer et al., 1997 source
- Interpretationnone given
This study is the first systematic review and meta-analysis of prospective associations between sleep disturbance and suicidal thoughts and behaviors.
“The current study provided the first systematic review and meta-analysis of prospective associations between sleep disturbance and STBs.”
Quote in the paperSubstantial claim - Premisecitation
An earlier meta-analysis that evaluated whether the strength of association between sleep disturbance and suicidality was moderated by cross-sectional versus longitudinal design featured only seven studies eligible for the current review.
“an earlier meta-analysis (Pigeon et al., 2012) that evaluated whether the strength of association between sleep disturbance and suicidality was moderated by the adoption of a cross-sectional versus longitudinal design featured only seven studies that were eligible for the current review.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Pigeon et al., 2012 source
- Study design and conductown data
No evidence of publication bias was found for insomnia as a predictor of later suicide deaths.
“No evidence of publication bias was found for insomnia as a prospective predictor of suicide deaths.”
Quote in the paperNot a substantial claim - Study design and conductown data
For overall sleep disturbance and later suicide attempts, only Egger's regression test suggested publication bias.
“For the relation between sleep disturbance and prospective suicide attempts, only Egger’s regression test indicated the presence of publication bias.”
Quote in the paperNot a substantial claim - Premisereasoning
Random-effects models are more fitting than fixed-effects models when high heterogeneity is expected because they account for sampling and study-level errors.
“Random-effects models are more fitting than fixed-effects models in this case because they are able to account for this high heterogeneity by including sampling and study-level errors”
Quote in the paperSubstantial claim - Study design and conductreasoning
Random-effects models were generated for all analyses to account for expected high heterogeneity across studies.
“Random-effects models were generated for all analyses to account for the expected high heterogeneity across studies due to differences in design, measures, and samples.”
Quote in the paperSubstantial claim - Interpretationreasoning
The evidence base for treating sleep disturbance as a warning sign for suicidal behavior is relatively modest, resting mainly on cross-sectional or retrospective studies.
“This means that the evidence base for this conceptualization of sleep disturbance as a warning sign is relatively modest, being based essentially on cross-sectional or retrospective studies.”
Quote in the paperSubstantial claim - Study design and conductown data
Evidence of publication bias was found for insomnia in relation to later suicidal ideation and later suicide attempts.
“Evidence of publication bias was found for insomnia in relation to prospective suicidal ideation and suicide attempts, respectively.”
Quote in the paperSubstantial claim - Study design and conductown data
For overall sleep disturbance and later suicide deaths, Egger's regression test found no evidence of publication bias.
“As for sleep disturbance in relation to prospective suicide deaths, Egger’s regression test yielded no evidence of publication bias whereas both the trim-and-fill analysis and the corresponding funnel plot (Figure 2c) suggested that the existing literature may underestimate the strength of this association (adjusted d = .58, 95% CI = .31 – .86).”
Quote in the paperNot a substantial claim - Interpretationcitation
Greater representation of cross-sectional studies in prior meta-analyses may have led to an overestimate of the strength of the relation between sleep disturbance indices and suicide risk.
“it is possible that the greater representation of cross-sectional studies in these prior meta-analyses may have led to an overestimate of the strength of the relation between sleep disturbance indices and suicide risk”
Quote in the paperSubstantial claim - Premisecitation
Even among traditionally high-risk populations, most individuals do not engage in suicidal behavior.
“This is an important consideration because even among traditionally high-risk populations, the majority of individuals do not engage in suicidal behavior (American Psychiatric Association, 2004; Lau et al., 2004; Liu et al., 2012; Nock et al., 2008; Sokero et al., 2006).”
Quote in the paperSubstantial claim0 of 3 sources checked - Study design and conductown data
For overall sleep disturbance predicting later suicidal ideation, the meta-analysis found evidence of publication bias according to Egger's regression test, trim-and-fill, and an asymmetric funnel plot.
“Evidence of publication bias was found for the association between sleep disturbance and future suicidal ideation (see Table 2), based on Egger’s regression test, Trim-and-fill analysis, and an asymmetrical funnel plot (Figure 2a).”
Quote in the paperSubstantial claim - Premisecitation
Several markers of inflammation, such as IL-6, have been implicated in suicide risk.
“Several markers of inflammation (e.g., IL-6), in turn, have been implicated in suicide risk (Black & Miller, 2015).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Black & Miller, 2015 source
- Interpretationreasoning
Without repeated assessments before or after, it is unclear how much such sleep measures reflect chronic versus acute irregularities.
“Specifically, without the reference point of repeated assessments taken before or after, it is unclear to what degree such measures of sleep index irregularities that are chronic versus acute (i.e., deviations from the individual’s baseline).”
Quote in the paperSubstantial claim - Premisecitation
Abnormal elevations in pro-inflammatory cytokines have been found in cerebrospinal fluid and post-mortem brain samples of suicidal individuals.
“Indeed, peripheral cytokines may produce neuroinflammatory responses through several pathways and processes, including communicating through the vagus nerve and microglial activation (Debnath et al., 2011), and abnormal elevations in these pro-inflammatory cytokines have been identified in the cerebrospinal fluid and post-mortem brain samples of suicidal individuals (Black & Miller, 2015).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Black & Miller, 2015 source
- Interpretationown data
In summary, sleep disturbance, including insomnia, appears to prospectively predict suicidal thoughts and behaviors with small-to-medium to medium effect sizes.
“In summary, sleep disturbance, including insomnia, appears to be prospectively predictive of STBs, with small-to-medium to medium effect sizes for these associations.”
Quote in the paperSubstantial claim - Premisecitation
Cognitive behavioral therapy for insomnia has been found to reduce some markers of inflammation.
“Additionally, therapeutic interventions for insomnia (i.e., cognitive behavioral therapy for insomnia [CBT-I]) have been found to produce reductions in some markers of inflammation (Irwin & Piber, 2018).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Irwin & Piber, 2018 source
- Classified as probably not a substantial claim. 22
- May combine two claims. 42
- The quote only partly states this claim. 1
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationSleep disruption has been conceptualized as a manifestation of the over-arousal characteristic of acute suicide risk.
“sleep disruption has been conceptualized as a manifestation of the over-arousal characteristic of this period of acute suicide risk (Ribeiro et al., 2015; Rogers et al., 2016; Tucker et al., 2016).”
Quote in the paperNot a substantial claim1 of 3 sources checkedClassified as probably not a substantial claim.
PremisecitationSeveral current theoretical perspectives hold that acute suicide risk occurs during relatively short-lived periods of heightened arousal or agitation.
“several current theoretical perspectives hold that acute suicide risk occurs during relatively short-lived periods of heightened arousal or agitation (Deisenhammer et al., 2009; Miller & Prinstein, 2019; Tucker et al., 2016; Wolfe-Clark & Bryan, 2017)”
Quote in the paperSubstantial claim1 of 3 sources checkedMay combine two claims.
PremisecitationA more recent meta-analysis focusing exclusively on psychiatric patient samples categorized 11 studies as employing a longitudinal design, and just six of these featured longitudinal analyses.
“A more recent meta-analysis, focusing exclusively on psychiatric patient samples (Malik et al., 2014) categorized 11 studies as employing a longitudinal design, and just six of these featured longitudinal analyses.”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Malik et al., 2014 source
The Results section (‘Description and quality of included studies’; page unavailable) reports that 11 of 19 studies were prospective, supporting the count of longitudinal designs. The paper concerns psychiatric patients, but the passages do not establish that only six of those studies performed longitudinal analyses; searches for that distinction found no supporting passage. (LLM, conf=0.86)
Experimental — accuracy not yet measured
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationI2 values of approximately 25%, 50%, and 75% indicate low, moderate, and substantial heterogeneity, respectively.
“Low heterogeneity is indicated by I2 values of approximately 25%, and moderate heterogeneity by I2 values of 50%. Substantial heterogeneity attributed to real differences in study samples and methodology is indicated by an I2 value of 75%”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Higgins et al., 2003 source
In “How much is too much heterogeneity?” (page not indicated), the paper tentatively labels I² values of 25%, 50%, and 75% as low, moderate, and high. It cautions that these labels are not appropriate in every circumstance; a value of 75% alone does not establish that differences in study samples and methodology caused the heterogeneity. (LLM, conf=0.84)
Experimental — accuracy not yet measured
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationPsychosocial stress impairs sleep.
“Although it has been proposed that this theory may apply to suicide (Bernert & Joiner, 2007) and psychosocial stress does indeed impair sleep (Kim & Dimsdale, 2007), this possibility remains untested.”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites Kim & Dimsdale, 2007 source
May combine two claims.
PremisecitationChronic or relatively stable processes and characteristics are likely more relevant to long-term or general risk, and their low temporal variance makes them less able to predict short-term risk robustly.
“This is an important consideration because chronic or relatively stable processes and characteristics are likely more relevant to understanding long-term or general risk (Glenn et al., 2017), and their relatively low temporal variance means they lack the temporal sensitivity required to be robust predictors of short-term risk.”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Glenn et al., 2017 source
May combine two claims.
PremisecitationA few studies found evidence that the sleep-STB association is unidirectional: sleep predicts later suicidal thoughts and behaviors, at least suicidal ideation, but suicidal ideation does not predict later sleep behavior.
“It is therefore noteworthy that in addition to demonstrating temporal precedence in the relation between sleep disturbance and STBs, a few studies have found evidence that this association is unidirectional; not only does sleep temporally predict STBs, at least in the case of suicidal ideation, but suicidal ideation, in turn, does not predict subsequent sleep behavior (Littlewood et al., 2019;”
Quote in the paperSubstantial claim1 of 2 sources checkedMay combine two claims.
PremisecitationState-sensitive phenomena are more promising for short-term risk and likely poor indicators of long-term risk.
“Contrastingly, state-sensitive phenomena are more promising candidates for short-term risk (Glenn & Nock, 2014) and likely poor indicators of long-term risk.”
Quote in the paperSubstantial claim1 of 1 sources checked- cites Glenn & Nock, 2014 source
May combine two claims.
Findingown dataSleep disturbance, including insomnia, prospectively predicted suicidal thoughts and behaviors, with effect sizes ranging from small-to-medium to medium.
“Sleep disturbance, including insomnia, prospectively predicted STBs, yielding small-to-medium to medium effect sizes for these associations.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFew studies of suicidal ideation and suicide attempts, and none of suicide deaths, assessed short-term risk using follow-up assessments of under a month.
“few studies of suicidal ideation and suicide attempts, as well as none of suicide deaths, assessed short-term risk (i.e., employed follow-up assessments of under a month).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataOnly two studies examined sleep disturbance in relation to suicide attempts over a follow-up of one month or less, and none examined this for suicide deaths.
“As only two studies evaluated sleep disturbance in relation to suicide attempts over a follow-up period of one month or briefer, and none in the case of sleep disturbance predicting suicide deaths”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataStudies of overall sleep disturbance predicting later suicidal ideation over less than a year had significantly larger effects than studies with follow-ups of a year or more, and follow-up length remained a significant moderator in meta-regression.
“Supportive of an influence of length of follow-up on weighted effect sizes, studies of overall sleep disturbance prospectively predicting suicidal ideation over a period of under a year yielded significantly larger effects than did those with follow-ups of a year or more, and the moderator effect of follow-up length remained significant in a meta-regression analysis.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor insomnia and later suicide attempts, Egger's test indicated significant publication bias, and trim-and-fill correction produced a larger pooled effect, adjusted d = .44, 95% CI .15 to .73.
“In both cases, Egger’s regression test indicated the existence of significant publication bias. Trim-and-fill analyses and corresponding funnel plots (Figures 2d and 2e), however, indicated whereas correcting for publication bias would yield a smaller pooled effect for suicidal ideation (adjusted d = .37, 95% CI = .25 – .49), it would produce a larger pooled effect in the case of suicide attempts”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataIn the case of sleep disturbance in relation to later suicide attempts, only suicide measure type emerged as a significant moderator, with a larger pooled effect observed for questionnaire measures (d = .53, 95% CI .27-.79) than for interview-based ones (d = .12, 95% CI −.08-.32).
“In the case of sleep disturbance in relation to later suicide attempts, only suicide measure type emerged as a significant moderator, with a larger pooled effect observed for questionnaire measures (d = .53, 95% CI = .27 – .79) than for interview-based ones (d = .12, 95% CI = −.08 – .32).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor insomnia, median follow-up increased from 10.5 months for suicidal ideation to two years for suicide attempts to 8.7 years for suicide deaths.
“A nearly identical pattern was observed for insomnia, with median follow-ups increasing from 10.5 months for suicidal ideation to two years for suicide attempts to 8.7 years for suicide deaths.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor hypersomnia and suicidal ideation, the pooled effect was trivial and non-significant, d = .09, 95% CI −.07 to .25.
“Overall, evidence for an association between hypersomnia and STBs appeared modest, with non-significant pooled effects that were trivial for suicidal ideation (d = .09, 95% CI = −.07 – .25) and small-to-medium for suicide attempts (d = .31, 95% CI = −.56 – 1.17).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataIn univariate moderator analyses, sleep measure type and length of study follow-up assessment moderated the association between sleep disturbance and prospective suicidal ideation.
“In univariate moderator analyses, sleep measure type and length of study follow-up assessment moderated the association between sleep disturbance and prospective suicidal ideation.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor overall sleep disturbance and later suicide deaths, trim-and-fill and the funnel plot indicated that the literature may underestimate the association, with adjusted d = .58, 95% CI .31 to .86.
“As for sleep disturbance in relation to prospective suicide deaths, Egger’s regression test yielded no evidence of publication bias whereas both the trim-and-fill analysis and the corresponding funnel plot (Figure 2c) suggested that the existing literature may underestimate the strength of this association (adjusted d = .58, 95% CI = .31 – .86).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataWhen follow-up lengths of a month or briefer versus over a month were considered, both length of follow-up assessment (b = .26, p < .01) and sleep measure type (b = .26, p = .02) remained significant moderators, with this multivariate model accounting for 67% of the variance in effect sizes for the association between sleep disturbance and suicidal ideation.
“When follow-up lengths of a month or briefer versus over a month were considered, both length of follow-assessment (b = .26, p < .01) and sleep measure type (b = .26, p = .02) remained significant moderators, with this multivariate model account for 67% of the variance in effect sizes for the association between sleep disturbance and suicidal ideation.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataFor insomnia predicting suicide deaths, the pooled effect was small-to-medium, d = .30, 95% CI .20 to .41, with follow-ups from one to 36 years and a median of 8.7 years.
“As for insomnia as a predictor of suicide deaths, a small-to-medium pooled effect was found (d = .30, 95% CI = .20 – .41), with follow-ups ranging from one to 36 years (median follow-up length = 8.7 years).”
Quote in the paperSubstantial claimMay combine two claims. The quote only partly states this claim.
Findingown dataFor hypersomnia and suicide attempts, the pooled effect was small-to-medium and non-significant, d = .31, 95% CI −.56 to 1.17.
“Overall, evidence for an association between hypersomnia and STBs appeared modest, with non-significant pooled effects that were trivial for suicidal ideation (d = .09, 95% CI = −.07 – .25) and small-to-medium for suicide attempts (d = .31, 95% CI = −.56 – 1.17).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor insomnia and later suicidal ideation, Egger's test indicated significant publication bias, and trim-and-fill correction produced a smaller pooled effect, adjusted d = .37, 95% CI .25 to .49.
“In both cases, Egger’s regression test indicated the existence of significant publication bias. Trim-and-fill analyses and corresponding funnel plots (Figures 2d and 2e), however, indicated whereas correcting for publication bias would yield a smaller pooled effect for suicidal ideation (adjusted d = .37, 95% CI = .25 – .49), it would produce a larger pooled effect in the case of suicide attempts”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataSignificant heterogeneity was present for suicidal ideation, suicide attempt, and suicide death, and thus moderator analyses were indicated.
“Significant heterogeneity was present for suicidal ideation, suicide attempt, and suicide death, and thus moderator analyses were indicated.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingnone givenNone of the studies with suicide deaths had follow-ups shorter than a year.
“Incidentally, none of the studies with suicide deaths included follow-ups briefer than a year.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataWhen follow-ups of one month or less were compared with longer follow-ups, the pooled effect was medium-to-large for up to one month and small-to-medium for longer follow-ups.
“This finding held when follow-ups of a month or briefer were compared to longer follow-ups, with a medium-to-large pooled effect observed for follow-ups of up to one month compared to a small-to-medium pooled effect in the case of longer follow-ups.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor suicide deaths, moderator analyses could not be conducted for age as a categorical variable, time-frame covered by the sleep measure, suicide measure type, time-frame covered by the suicide measure, and length of follow-up assessment.
“In the case of suicide deaths, it was not possible to conduct moderator analyses for age as a categorical variable (i.e., all but one sample was with adults), time-frame covered by the sleep measure (i.e., all studies either had time-frames of less than a month or provided no information on this design feature), suicide measure type (i.e., all studies used death records), time-frame covered by the”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataOnly four included studies of overall sleep disturbance and suicide attempts had follow-ups under a year, compared with 13 studies for suicidal ideation.
“Although follow-up length did not also significantly moderate the strength of the association between overall sleep disturbance and suicide attempts, only four of the included studies featured follow-ups of under a year, in contrast to 13 in the case of suicidal ideation.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataFor overall sleep disturbance, median follow-up increased with outcome severity: 10.5 months for suicidal ideation, two years for suicide attempts, and 10 years for suicide deaths.
“For overall sleep disturbance, median follow-ups were quite substantial, increasing in duration with increasing severity of STB, from 10.5 months for suicidal ideation to two years for suicide attempts to 10 years for suicide deaths.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataA notable proportion of included studies did not report sample race data, and even fewer reported ethnicity, though reporting appears to have improved in recent years.
“First, a notable proportion of studies did not report data on the race of their samples, and even fewer on ethnicity, although there appears to be improvement in reporting practices in more recent years.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataSix studies of overall sleep disturbance and suicidal ideation had follow-ups of one month or less, while only two studies with suicide attempts had comparable follow-up intervals.
“Six studies of overall sleep disturbance and suicidal ideation included follow-ups of one month or briefer, whereas only two studies with suicide attempts as the outcome featured follow-up intervals of comparable length.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
FindingreasoningThe final set comprised 41 articles included in the review.
“This resulted in a final set of 41 articles included in the current review”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataA total of 26 unique effects were obtained for the association between sleep disturbance and prospective suicidal ideation, 13 for future suicide attempts, and 14 for associations with suicide deaths.
“A total of 26 unique effects were obtained for the association between sleep disturbance and prospective suicidal ideation, 13 for future suicide attempts, and 14 for associations with suicide deaths”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThe study with the shortest follow-up for suicide attempts, three days, had the largest effect among studies with that outcome, d = .85.
“Of note, the study with the briefest follow-up period for suicide attempts (i.e., three days; Ribeiro, Huang, Fox, Walsh, & Linthicum, 2019) yielded the largest effect (d = .85) among studies”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Ribeiro, Huang, Fox, Walsh, & Linthicum, 2019 source
May combine two claims.
PremisereasoningSignificantly less empirical research has focused on the relationship between sleep indices and suicide outcomes using longitudinal designs, leaving unclear the strength of sleep disturbance as a true risk factor for suicidal thoughts and behaviors.
“Significantly less empirical research has focused on the relationship between sleep indices and suicide outcomes utilizing longitudinal designs, leaving unclear the strength of sleep disturbance as a true risk factor for STBs.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim. May combine two claims.
PremisereasoningCorrelates are determined with cross-sectional designs, lack evidence of temporal precedence, cannot establish prospective prediction, and cannot be ruled out as concomitants or epiphenomena of the mental health outcome.
“In contrast to risk factors, correlates are determined with cross-sectional designs and therefore lack evidence of temporal precedence; correlates cannot establish prospective prediction and cannot be ruled out as concomitants or epiphenomena of the mental health outcome of interest.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationThe pooled effects for sleep disturbance and suicidal thoughts and behaviors are generally similar in size to those in meta-analyses of psychological and psychopharmacology treatments for mental health conditions, often over shorter periods.
“As additional context for interpreting these pooled effects, it may be noted that they are generally comparable in size to those found in meta-analyses of psychological and psychopharmacology therapies for a variety of mental health conditions, often over much briefer periods of time (e.g., Cuijpers et al., 2010, 2014; Weisz et al., 2017).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites Cuijpers et al., 2010, 2014
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Weisz et al., 2017 source
Classified as probably not a substantial claim. May combine two claims.
PremisereasoningStudies with small effect sizes or non-significant findings are less likely to be published, may be more likely to be excluded from meta-analyses, and can result in a potentially inflated estimate of the overall effect size.
“As studies with small effect sizes or non-significant findings are less likely to be published, these studies may be more likely to be excluded from meta-analyses, resulting in a potentially inflated estimate of the overall effect size.”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataExcept for a preliminary non-significant association between hypersomnia and later suicidal ideation, results across overall sleep disturbance, insomnia, hypersomnia, and nightmares consistently showed positive associations with all later suicidal thoughts and behaviors.
“With the exception of a preliminary finding of a non-significant relation between hypersomnia and subsequent suicidal ideation, the results of analyses across several manifestations of sleep disturbance (i.e., overall disturbance, insomnia, hypersomnia, and nightmares) were consistent in yielding positive associations with all subsequent STBs (i.e., suicidal ideation, suicide attempts, and suicide”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationStandard guidelines classify Cohen's d of .20 as small, .50 as medium, and .80 as large.
“Standard guidelines for Cohen’s d were used to determine the size of the effect (i.e., .20 = small effect size, .50 = medium, and .80 = large; Kraemer et al., 2003).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Kraemer et al., 2003 source
Probably not a substantial claim: may not pass S4 (based).
InterpretationreasoningSleep disturbance may confer risk for suicidal thoughts and behaviors through neuroinflammatory and stress processes and associated impairments in executive control.
“providing a model of how sleep disturbance may confer risk for STBs through neuroinflammatory and stress processes and associated impairments in executive control.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThese reporting findings are generally consistent with a recent systematic review of sample-characteristic reporting in the suicide literature.
“These findings are generally consistent with those in a recent systematic review of reporting practices of sample characteristics in the suicide literature (Cha et al., 2018).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Cha et al., 2018 source
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisereasoningSignificant heterogeneity suggests the need to conduct moderator analyses to identify potential sources.
“Significant heterogeneity suggests the need to conduct moderator analyses to identify potential sources of this heterogeneity.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Study design and conductcitationDuval and Tweedie's trim-and-fill analysis and Egger's regression intercept were used to account for potential publication bias.
“To account for the presence of potential publication bias, Duval and Tweedie’s trim-and-fill analysis (Duval & Tweedie, 2000) and Egger’s regression intercept (Egger et al., 1997) were used.”
Quote in the paperSubstantial claim0 of 2 sources checked- The authors state this as an assumption: Duval and Tweedie’s trim-and-fill procedure assumes homogeneity of effect sizes.
May combine two claims.
InterpretationreasoningThe body of literature has expanded considerably since the earlier meta-analysis, such that there are now sufficient longitudinal studies to observe the distinction between each form of suicidal thought and behavior in separate meta-analyses.
“The body of literature has expanded considerably since then such that the small number of available longitudinal studies at the time necessitated collapsing across STBs in evaluating the association between sleep disturbance and suicide, whereas there are now a sufficient number of longitudinal studies to observe the important distinction between each form of STB in separate meta-analyses.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationThe two remaining meta-analyses focused exclusively on sleep behavior in adolescents, with one featuring only two studies with longitudinal analyses included in the current review, and the other none.
“The two remaining meta-analyses focused exclusively on sleep behavior in adolescents, with one featuring only two studies with longitudinal analyses included in the current review (Liu, Tu, et al., 2019), and the other none (Chiu et al., 2018).”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites Liu, Tu, et al., 2019
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites Chiu et al., 2018 source
May combine two claims.
PremisecitationOnly one systematic review has focused specifically on longitudinal associations between sleep and suicide, a narrative review of adolescent studies.
“there has been only one systematic review focusing specifically on longitudinal associations between sleep and suicide, a narrative review of adolescent studies.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Kearns et al., 2020 source
Classified as probably not a substantial claim.
InterpretationreasoningA possible reason for the smaller interview effects is that most interview measures were not designed to assess sleep and instead used items from diagnostic depression interview modules.
“It is possible that this finding emerged given that the majority of the interview measures used were not specifically designed to measure sleep, and instead used items pulled from diagnostic interview depression modules (e.g., Hamilton Depression Rating Scale, the Schedule for Affective Disorders and Schizophrenia).”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataFor overall sleep disturbance and insomnia, pooled effect sizes fell in the small-to-medium to medium range, ds = .30 to .50, and changed little after publication-bias adjustment.
“For overall sleep disturbance and insomnia, both having a sizeable number of unique effects for quantitative analyses, the pooled effect sizes were all within the small-to-medium to medium range (ds = .30 to .50), which remained largely unchanged after adjusting for potential publication bias.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenEach search result was independently reviewed for eligibility by two authors, with discrepancies resolved by a third author.
“Each search result was independently reviewed for eligibility by two authors. In the event of a discrepancy between authors, it was resolved independently by a third author.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataSleep disturbance and insomnia have enough predictive power to yield pooled effect sizes of ds ≥ .39 and .30, respectively, over long follow-up periods, which indicates their value for understanding suicide risk.
“That sleep disturbance and insomnia have sufficient predictive power to produce pooled effect sizes of ds ≥ .39 and .30, respectively, for these outcomes over such lengthy stretches of time speaks to their value in understanding suicide risk.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
PremisecitationOne prior meta-analysis found that cross-sectional designs may produce larger effect sizes (RR = 3.14) than longitudinal designs (RR = 1.94) in the relation between sleep disturbance and suicide risk.
“one of these prior meta-analyses has found that cross-sectional designs may produce larger effect sizes (RR = 3.14) than longitudinal designs (RR = 1.94) in this relation (Pigeon et al., 2012).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Pigeon et al., 2012 source
Classified as probably not a substantial claim.
PremisecitationThe majority of studies in that narrative review provided evidence of a prospective relation between sleep problems and suicidal thoughts and behaviors.
“The majority of the studies in this review provided evidence of a prospective relation between sleep problems and suicidal thoughts and behaviors (Kearns et al., 2020).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites Kearns et al., 2020 source
Probably not a substantial claim: may not pass S2 (checkable).
PremisereasoningPublication bias is an important consideration when conducting meta-analyses.
“Publication bias is an important consideration when conducting meta-analyses.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
InterpretationreasoningA conceptual model is outlined in which sleep disturbance participates in stress processes to confer suicide risk through neuroinflammation-induced impairments in executive control.
“Finally, as a potential framework for future work in this area, a conceptual model is outlined, wherein sleep disturbance is involved in stress processes to confer suicide risk through neuroinflammation-induced impairments in executive control.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationLife stress, especially interpersonal stressors, may play a prominent role in risk for suicidal thoughts and behaviors, particularly short-term risk.
“There is accumulating evidence that life stress, particularly interpersonal stressors, may play a prominent role in risk for STB (Liu & Miller, 2014), especially short-term risk (Bagge et al., 2013).”
Quote in the paperNot a substantial claim0 of 2 sources checkedMay combine two claims.
Interpretationnone givenMost studies to date have evaluated sleep disturbance as a long-term risk factor for suicidal thoughts and behaviors, leaving unclear how well disrupted sleep predicts short-term risk.
“The vast majority of studies to date, however, have evaluated sleep disturbance as a long-term risk factor for STBs, leaving unclear the degree to which disrupted sleep predicts short-term risk, a question of considerable clinical relevance, given that clinical risk assessments are more focused on determining whether an individual will engage in suicidal behavior in the near future.”
Quote in the paperSubstantial claim- Rests on an assumption: Clinical risk assessments focus on determining whether an individual will engage in suicidal behavior in the near future.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationSocial zeitgeber theory holds that psychosocial stress may increase depression risk by disrupting social routines and thereby biological circadian rhythms.
“Interestingly, theoretical support for interpersonal stress leading to sleep dysregulation relevant to suicide risk may be found in the social zeitgeber theory (Ehlers et al., 1988). This theory holds that psychosocial stress may increase risk for depression by disrupting an individual’s social routines, and thereby their biological circadian rhythms.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Ehlers et al., 1988 source
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationSuicide risk has been found to be elevated or increasing in several traditionally underrepresented racial and ethnic populations.
“Thorough reporting of sample sociodemographic characteristics is important for evaluating the generalizability of findings to traditionally underrepresented racial and ethnic groups, especially as risk for suicide has been found to be elevated or increasing in several of these populations (Sheftall et al., 2016).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites Sheftall et al., 2016 source
The authors state this as an assumption.
Duval and Tweedie’s trim-and-fill procedure assumes homogeneity of effect sizes.
“Of note, this procedure assumes homogeneity of effect sizes, so the results must be interpreted with caution in the context of significant heterogeneity.”
The paper relies on this without support.
Suicide attempts and deaths are low-base-rate events, with attempts relatively infrequent in the general population and deaths considerably rarer.
“The reason for the want of research on short-term risk is that, although suicide is a leading cause of death (Centers for Disease Control and Prevention, 2019; World Health Organization, 2019), it is nevertheless a low-base-rate event; suicide attempts occur with relatively low frequency in the general population, and suicide deaths are considerably rarer still.”
The paper relies on this without support.
Clinical risk assessments focus on determining whether an individual will engage in suicidal behavior in the near future.
“a question of considerable clinical relevance, given that clinical risk assessments are more focused on determining whether an individual will engage in suicidal behavior in the near future.”
The paper relies on this without support.
Several prominent suicide prevention organizations highlight sleep disturbance as a warning sign for suicidal behavior.
“The want of short-term risk studies is all the more concerning when considered together with the fact that sleep disturbance, as mentioned above, is highlighted by several prominent suicide prevention organizations as a warning sign (i.e., precipitant) for suicidal behavior.”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Discussion overlooks a second nonsignificant hypersomnia result
MinorThe discussion singles out hypersomnia and suicidal ideation as the nonsignificant exception, but the results also describe the pooled hypersomnia-suicide-attempt effect as nonsignificant.
“With the exception of a preliminary finding of a non-significant relation between hypersomnia and subsequent suicidal ideation, the results of analyses across several manifestations of sleep disturbance (i.e., overall disturbance, insomnia, hypersomnia, and nightmares) were consistent in yielding positive associations with all subsequent STBs”
“with non-significant pooled effects that were trivial for suicidal ideation (d = .09, 95% CI = −.07 – .25) and small-to-medium for suicide attempts (d = .31, 95% CI = −.56 – 1.17).”
Short-follow-up effect is off-center in its confidence interval
MinorThe reported effect of 0.61 is not centered in its stated 95% confidence interval: the limits have a midpoint of 0.12. The other reported meta-analytic intervals are approximately centered on their effects.
Reported 0.61 · recomputed 0.12
“a month or briefer (d = .61, 95% CI = −.49 – .73)”
Longer-follow-up effect is off-center in its confidence interval
MinorThe stated interval for the 0.34 effect has a midpoint of 0.105, far from the reported estimate. This exceeds any difference attributable to rounding.
Reported 0.34 · recomputed 0.105
“over a month (d = .34, 95% CI = −.23 – .44)”
Longer-follow-up effect is not centered in its confidence interval
MinorThe reported effect of .34 is not the midpoint of its stated 95% confidence interval; the midpoint is .105. This discrepancy exceeds rounding to the printed precision.
Reported 0.34 · recomputed 0.105
“(d = .34, 95% CI = −.23 – .44)”
Short-follow-up effect is not centered in its confidence interval
MinorThe reported effect of .61 is not the midpoint of its stated 95% confidence interval; the midpoint is .12. The other reported effect and confidence interval in this comparison have the same problem.
Reported 0.61 · recomputed 0.12
“(d = .61, 95% CI = −.49 – .73)”
Cites
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139 · see citing works
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722 · cited 1× · see citing works
“To account for the presence of potential publication bias, Duval and Tweedie’s trim-and-fill analysis (Duval & Tweedie, 2000) and Egger’s regression intercept (Egger et al., 1997) were used.”
MethodDuval, S., & Tweedie, R. (2000) · Biometrics · doi:10.1111/j.0006-341x.2000.00455.x · Cited by 14,099 · see citing works
Diamond, A. (2013) · Annual Review of Psychology · doi:10.1146/annurev-psych-113011-143750 · Cited by 13,268 · cited 1× · see citing works
“Also relevant are findings that executive functions are the cognitive systems to be first, and most severely, impaired by sleep deprivation (Diamond, 2013).”
BackgroundRisk factors for suicidal thoughts and behaviors: A meta-analysis of 50 years of research
Franklin, J. C., Ribeiro, J. D., Fox, K. R., Bentley, K. H., Kleiman, E. M., Huang, X., Musacchio, K. M., Jaroszewski, A. C., Chang, B. P., & Nock, M. K. (2017) · Psychological Bulletin · doi:10.1037/bul0000084 · Cited by 3,784 · cited 2× · see citing works
“A uthor M anuscript A uthor M anuscript A uthor M anuscript A uthor M anuscript analysis (Bredemeier & Miller, 2015; Franklin et al., 2017; Wenzel et al., 2011), thus the pattern found in the current review of median follow-up lengths increasing substantially with severity of STB.”
MethodNock, M. K., Borges, G., Bromet, E. J., Cha, C. B., Kessler, R. C., & Lee, S. (2008) · Epidemiologic Reviews · doi:10.1093/epirev/mxn002 · Cited by 2,897 · cited 2× · see citing works
“This is an important consideration because even among traditionally high-risk populations, the majority of individuals do not engage in suicidal behavior (American Psychiatric Association, 2004; Lau et al., 2004; Liu et al., 2012; Nock et al., 2008; Sokero et al., 2006).”
BackgroundIrwin, M. R., Olmstead, R., & Carroll, J. E. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.05.014 · Cited by 2,085 · cited 1× · see citing works
“, elevations in interleukin-6 [IL-6] and C-reactive protein [CRP]) has received substantial support from observational and experimental studies (Irwin et al., 2016; Irwin & Piber, 2018).”
BackgroundWeb-based Injury Statistics Query and Reporting System (WISQARS)
:unav (2009) · Harvard Dataverse · doi:10.7910/dvn/n8emxe · Cited by 1,803 · see citing works
Suicide, Suicide Attempts, and Suicidal Ideation
Klonsky, E. D., May, A. M., & Saffer, B. Y. (2016) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-021815-093204 · Cited by 1,675 · cited 2× · see citing works
“In particular, one approach for increasing the number of observations of events occurring at a low base rate is to include very large samples, although this strategy has feasibility challenges of its own (Klonsky et al., 2016; Prinstein, 2008).”
BackgroundComing to terms with the terms of risk
Kraemer, H. C. (1997) · Archives of General Psychiatry · doi:10.1001/archpsyc.1997.01830160065009 · Cited by 1,432 · cited 1× · see citing works
“A longitudinal design is necessary to assess the extent to which a variable may be considered a risk factor, temporally preceding the outcome of interest (Kraemer et al., 1997).”
BackgroundTime-related predictors of suicide in major affective disorder
FAWCETT, J. A., Scheftner, W. A., Fogg, L., Clark, D. C., Young, M. A., Hedeker, D., & Gibbons, R. D. (1990) · American Journal of Psychiatry · doi:10.1176/ajp.147.9.1189 · Cited by 1,058 · see citing works
Weisz, J. R., Kuppens, S., Ng, M. Y., Eckshtain, D., Ugueto, A. M., Vaughn-Coaxum, R., Jensen-Doss, A., Hawley, K. M., Krumholz Marchette, L. S., Chu, B. C., et al. (2017) · American Psychologist · doi:10.1037/a0040360 · Cited by 862 · cited 2× · see citing works
“As additional context for interpreting these pooled effects, it may be noted that they are generally comparable in size to those found in meta-analyses of psychological and psychopharmacology therapies for a variety of mental health conditions, often over much briefer periods of time (e.g., Cuijpers et al., 2010, 2014…”
ResultMeta-analysis of sleep disturbance and suicidal thoughts and behaviors
Pigeon, W. R., Pinquart, M., & Conner, K. (2012) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.11r07586 · Cited by 815 · cited 4× · see citing works
“Although four of these prior systematic reviews were meta-analyses (Chiu et al., 2018; Liu, Tu, et al., 2019; Malik et al., 2014; Pigeon et al., 2012), which offer a unique advantage over narrative reviews in that they allow for quantitative estimates of the magnitude of the association between sleep disturbance and S…”
BackgroundMethodInfluentialEhlers, C. L. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800340076012 · Cited by 707 · cited 1× · see citing works
“Interestingly, theoretical support for interpersonal stress leading to sleep dysregulation relevant to suicide risk may be found in the social zeitgeber theory (Ehlers et al., 1988).”
BackgroundMars, B., Heron, J., Klonsky, E. D., Moran, P., O'Connor, R. C., Tilling, K., Wilkinson, P., & Gunnell, D. (2019) · The Lancet Psychiatry · doi:10.1016/s2215-0366(19)30030-6 · Cited by 546 · see citing works
The Effect of Psychosocial Stress on Sleep: A Review of Polysomnographic Evidence
Kim, E.-J., & Dimsdale, J. E. (2007) · Behavioral Sleep Medicine · doi:10.1080/15402000701557383 · Cited by 448 · see citing works
Prinstein, M. J., Nock, M. K., Simon, V., Aikins, J. W., Cheah, C. S. L., & Spirito, A. (2008) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.76.1.92 · Cited by 435 · cited 3× · see citing works
“…statistical power for meaningful analysis (American Psychiatric Association, 2004; Borges et al., 2006; Klonsky et al., 2016; Nock et al., 2008; Prinstein, 2008; Prinstein et al., 2008), an obstacle most often addressed by including longer follow-up periods so as to maximize the number of STBs…”
BackgroundPaffenbarger, R. S., Lee, I.-M., & Leung, R. (1994) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1994.tb05796.x · Cited by 430 · see citing works
Cuijpers, P., Sijbrandij, M., Koole, S. L., Andersson, G., Beekman, A. T., & Reynolds, C. F. (2014) · World Psychiatry · doi:10.1002/wps.20089 · Cited by 424 · see citing works
Sleep disturbances as an evidence-based suicide risk factor
Bernert, R. A., Kim, J. S., Iwata, N. G., & Perlis, M. L. (2015) · Current Psychiatry Reports · doi:10.1007/s11920-015-0554-4 · Cited by 406 · cited 2× · see citing works
“To date, there have been six systematic reviews (Bernert et al., 2015; Chiu et al., 2018; Kearns et al., 2020; Liu, Tu, et al., 2019; Malik et al., 2014; Pigeon et al., 2012), all providing evidence suggesting that a range of sleep disturbances are indeed correlates of STBs.”
BackgroundMethodAdolescent Insomnia as a Risk Factor for Early Adult Depression and Substance Abuse
Roane, B. M., & Taylor, D. J. (2008) · SLEEP · doi:10.5665/sleep/31.10.1351 · Cited by 396 · see citing works
Proinflammatory cytokines in the prefrontal cortex of teenage suicide victims
Pandey, G. N., Rizavi, H. S., Ren, X., Fareed, J., Hoppensteadt, D. A., Roberts, R. C., Conley, R. R., & Dwivedi, Y. (2012) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.08.006 · Cited by 378 · cited 1× · see citing works
“, IL-6) has been found in the prefrontal cortex of suicide decedents (Pandey et al., 2012; also see Lutz, Mechawar, & Turecki, 2017).”
BackgroundMeasures of Clinical Significance
KRAEMER, H. C., MORGAN, G. A., LEECH, N. L., GLINER, J. A., VASKE, J. J., & HARMON, R. J. (2003) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200312000-00022 · Cited by 367 · cited 1× · see citing works
“Standard guidelines for Cohen’s d were used to determine the size of the effect (i.e., .20 = small effect size, .50 = medium, and .80 = large; Kraemer et al., 2003).”
MethodBlack, C., & Miller, B. J. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.10.014 · Cited by 366 · see citing works
Improving the Short-Term Prediction of Suicidal Behavior
Glenn, C. R., & Nock, M. K. (2014) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2014.06.004 · Cited by 328 · see citing works
Life events and suicidal ideation and behavior: a systematic review
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Self-citationPsychotherapy for chronic major depression and dysthymia: A meta-analysis
Cuijpers, P., van Straten, A., Schuurmans, J., van Oppen, P., Hollon, S. D., & Andersson, G. (2010) · Clinical Psychology Review · doi:10.1016/j.cpr.2009.09.003 · Cited by 320 · see citing works
Deisenhammer, E. A., Ing, C.-M., Strauss, R., Kemmler, G., Hinterhuber, H., & Weiss, E. M. (2009) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.07m03904 · Cited by 315 · cited 1× · see citing works
“Consistent with this position, several current theoretical perspectives hold that acute suicide risk occurs during relatively short-lived periods of heightened arousal or agitation (Deisenhammer et al., 2009; Miller & Prinstein, 2019; Tucker et al., 2016; Wolfe-Clark & Bryan, 2017), and sleep disruption has been conce…”
BackgroundRibeiro, J. D., Pease, J. L., Gutierrez, P. M., Silva, C., Bernert, R. A., Rudd, M. D., & Joiner, T. E. (2012) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.09.049 · Cited by 304 · see citing works
Suicide in elementary school-aged children and early adolescents
Sheftall, A. H., Asti, L., Horowitz, L. M., Felts, A., Fontanella, C. A., Campo, J. V., & Bridge, J. A. (2016) · Pediatrics · doi:10.1542/peds.2016-0436 · Cited by 271 · cited 1× · see citing works
“Thorough reporting of sample sociodemographic characteristics is important for evaluating the generalizability of findings to traditionally underrepresented racial and ethnic groups, especially as risk for suicide has been found to be elevated or increasing in several of these populations (Sheftall et al., 2016).”
BackgroundSleep disturbances and suicide risk: A review of the literature
Bernert, R. A. (2008) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s1248 · Cited by 260 · see citing works
Bernert, R. A., Turvey, C. L., Conwell, Y., & Joiner, T. E. (2014) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2014.1126 · Cited by 248 · see citing works
A risk index for 12-month suicide attempts in the National Comorbidity Survey Replication (NCS-R)
BORGES, G., ANGST, J., NOCK, M. K., RUSCIO, A. M., WALTERS, E. E., & KESSLER, R. C. (2006) · Psychological Medicine · doi:10.1017/s0033291706008786 · Cited by 246 · cited 2× · see citing works
“…challenge in the study of suicide of achieving sufficient statistical power for meaningful analysis (American Psychiatric Association, 2004; Borges et al., 2006; Klonsky et al., 2016; Nock et al., 2008; Prinstein, 2008; Prinstein et al., 2008), an obstacle most often addressed by including…”
BackgroundDeisenhammer, E., Ing, C.-M., Strauss, R., Kemmler, G., Hinterhuber, H., & Weiss, E. M. (2009) · PubMed · Cited by 237 · see citing works
Adolescent Suicide as a Failure of Acute Stress-Response Systems.
Miller, A. B., & Prinstein, M. J. (2019) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050718-095625 · Cited by 235 · see citing works
Lau, M. A., Segal, Z. V., & Williams, J. M. G. (2004) · Behaviour Research and Therapy · doi:10.1016/j.brat.2004.03.003 · Cited by 232 · cited 1× · see citing works
“This is an important consideration because even among traditionally high-risk populations, the majority of individuals do not engage in suicidal behavior (American Psychiatric Association, 2004; Lau et al., 2004; Liu et al., 2012; Nock et al., 2008; Sokero et al., 2006).”
BackgroundSleep problems, suicidal ideation, and self-harm behaviors in adolescence
Wong, M. M.-H., Brower, K. J., & Zucker, R. A. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2010.09.005 · Cited by 227 · see citing works
Nightmares as Predictors of Suicide
Tanskanen, A. J., Tuomilehto, J., Viinamäki, H. T., Vartiainen, E. A., Lehtonen, J., & Puska, P. (2001) · SLEEP · doi:10.1093/sleep/24.7.845 · Cited by 222 · see citing works
Littlewood, D. L., Kyle, S. D., Carter, L.-A., Peters, S., Pratt, D., & Gooding, P. (2019) · Psychological Medicine · doi:10.1017/s0033291718001009 · Cited by 209 · cited 2× · see citing works
“This resulted in additional data required for meta-analysis being obtained from the authors of three studies (Kivelä et al., 2019; Littlewood et al., 2019; Wang et al., 2019).”
BackgroundMethodMalik, S., Kanwar, A., Sim, L. A., Prokop, L. J., Wang, Z., Benkhadra, K., & Murad, M. H. (2014) · Systematic Reviews · doi:10.1186/2046-4053-3-18 · Cited by 206 · cited 4× · see citing works
“Although four of these prior systematic reviews were meta-analyses (Chiu et al., 2018; Liu, Tu, et al., 2019; Malik et al., 2014; Pigeon et al., 2012), which offer a unique advantage over narrative reviews in that they allow for quantitative estimates of the magnitude of the association between sleep disturbance and S…”
BackgroundMethodInfluentialLiu, R. T., Trout, Z. M., Hernandez, E. M., Cheek, S. M., & Gerlus, N. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.09.019 · Cited by 201 · cited 1× · see citing works
“Finally, different facets of executive control have, in turn, been associated with suicide risk (Liu et al., 2017; Miranda et al., 2012).”
BackgroundSelf-citationQuantifying the impact of recent negative life events on suicide attempts
Bagge, C. L., Glenn, C. R., & Lee, H.-J. (2013) · Journal of Abnormal Psychology · doi:10.1037/a0030371 · Cited by 201 · cited 1× · see citing works
“There is accumulating evidence that life stress, particularly interpersonal stressors, may play a prominent role in risk for STB (Liu & Miller, 2014), especially short-term risk (Bagge et al., 2013).”
BackgroundPrinstein, M. J. (2008) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.76.1.1 · Cited by 195 · cited 3× · see citing works
“…statistical power for meaningful analysis (American Psychiatric Association, 2004; Borges et al., 2006; Klonsky et al., 2016; Nock et al., 2008; Prinstein, 2008; Prinstein et al., 2008), an obstacle most often addressed by including longer follow-up periods so as to maximize the number of STBs…”
BackgroundPersistent nightmares are associated with repeat suicide attempt
Sjöström, N., Hetta, J. E., & Wærn, M. (2009) · Psychiatry Research · doi:10.1016/j.psychres.2008.09.006 · Cited by 174 · see citing works
Chiu, H.-Y., Lee, H.-C., Chen, P.-Y., Lai, Y.-F., & Tu, Y.-K. (2018) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2018.07.003 · Cited by 165 · cited 3× · see citing works
“Although four of these prior systematic reviews were meta-analyses (Chiu et al., 2018; Liu, Tu, et al., 2019; Malik et al., 2014; Pigeon et al., 2012), which offer a unique advantage over narrative reviews in that they allow for quantitative estimates of the magnitude of the association between sleep disturbance and S…”
BackgroundMethodWinsler, A., Deutsch, A., Vorona, R. D., Payne, P. A., & Szklo-Coxe, M. (2015) · Journal of Youth and Adolescence · doi:10.1007/s10964-014-0170-3 · Cited by 164 · cited 1× · see citing works
“Indeed, a decrease of even just one hour of sleep may be associated with significantly greater likelihood of these outcomes (Winsler et al., 2014).”
BackgroundExecutive function and suicidality: A systematic qualitative review
Bredemeier, K., & Miller, I. W. (2015) · Clinical Psychology Review · doi:10.1016/j.cpr.2015.06.005 · Cited by 160 · see citing works
Miranda, R., Gallagher, M., Bauchner, B., Vaysman, R., & Marroquín, B. (2012) · Depression and Anxiety · doi:10.1002/da.20915 · Cited by 159 · cited 6× · see citing works
“Furthermore, sleep disturbance is prominently featured as a warning sign (i.e., precipitating risk factor) for STBs by the American Association of Suicidology (American Association of Suicidology, 2019), the American Foundation for Suicide Prevention (American Foundation for Suicide Prevention, 2019), the National Ins…”
BackgroundInfluentialNeuropathology of suicide: Recent findings and future directions
Lutz, P.-E., Mechawar, N., & Turecki, G. (2017) · Molecular Psychiatry · doi:10.1038/mp.2017.141 · Cited by 158 · see citing works
Prospective predictors of adolescent suicidality: 6-month post-hospitalization follow-up
Yen, S., Weinstock, L. M., Andover, M. S., Sheets, E. S., Selby, E. A., & Spirito, A. (2013) · Psychological Medicine · doi:10.1017/s0033291712001912 · Cited by 154 · cited 2× · see citing works
“Furthermore, risk factors identified in non-clinical or community samples may be of limited generalizability to the clinical or high-risk individuals more often encountered by mental health care providers (for examples, see King, Berona, Czyz, Horwitz, & Gipson, 2015; Yen et al., 2013; for a related discussion, see Mi…”
BackgroundFujino, Y., Mizoue, T., Tokui, N., & Yoshimura, T. (2005) · Suicide and Life-Threatening Behavior · doi:10.1521/suli.35.2.227.62876 · Cited by 140 · see citing works
Liu, J.-W., Tu, Y.-K., Lai, Y.-F., Lee, H.-C., Tsai, P.-S., Chen, T.-J., Huang, H.-C., Chen, Y.-T., & Chiu, H.-Y. (2019) · Sleep · doi:10.1093/sleep/zsz054 · Cited by 137 · see citing works
Sleeping Problems and Suicide in 75,000 Norwegian Adults: A 20 Year Follow-up of the HUNT I Study
Bjørngaard, J. H., Bjerkeset, O. A., Romundstad, P., & Gunnell, D. (2011) · SLEEP · doi:10.5665/sleep.1228 · Cited by 133 · see citing works
Nocturnal Sleep Disturbances as a Predictor of Suicide Attempts Among Psychiatric Outpatients
Li, S. X., Lam, S. P., Yu, M. W. M., Zhang, J., & Wing, Y. K. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.09m05661gry · Cited by 123 · see citing works
Kearns, J. C., Coppersmith, D. D. L., Santee, A. C., Insel, C., Pigeon, W. R., & Glenn, C. R. (2020) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2018.09.011 · Cited by 115 · cited 3× · see citing works
“To date, there have been six systematic reviews (Bernert et al., 2015; Chiu et al., 2018; Kearns et al., 2020; Liu, Tu, et al., 2019; Malik et al., 2014; Pigeon et al., 2012), all providing evidence suggesting that a range of sleep disturbances are indeed correlates of STBs.”
BackgroundMethodGlenn, C. R., Cha, C. B., Kleiman, E. M., & Nock, M. K. (2017) · Clinical Psychological Science · doi:10.1177/2167702616686854 · Cited by 113 · cited 1× · see citing works
“This is an important consideration because chronic or relatively stable processes and characteristics are likely more relevant to understanding long-term or general risk (Glenn et al., 2017), and their relatively low temporal variance means they lack the temporal sensitivity required to be robust predictors of short-t…”
BackgroundNrugham, L., Larsson, B. S., & Sund, A. M. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.02.010 · Cited by 111 · see citing works
The prevention of recurrent suicidal acts.
Montgomery, S. A., Roy, D. H., & Montgomery, D. (1983) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1983.tb05864.x · Cited by 108 · see citing works
Sleep Disturbances and Suicide Risk
Bernert, R. A., & Nadorff, M. R. (2014) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2014.11.004 · Cited by 107 · see citing works
McMakin, D. L., Dahl, R. E., Buysse, D. J., Cousins, J. C., Forbes, E. E., Silk, J. S., Siegle, G. J., & Franzen, P. L. (2016) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12568 · Cited by 105 · cited 1× · see citing works
“In line with this possibility, a study using a sleep-deprivation paradigm found it to lead adolescents to behave in ways characterized by negative affect, conflict, withdrawal, and dominance during a social conflict task (McMakin et al., 2016).”
Li, S. X., Lam, S. P., Chan, J. W. Y., Yu, M. W. M., & Wing, Y. K. (2012) · SLEEP · doi:10.5665/sleep.2008 · Cited by 101 · see citing works
Construct validity of a proposed new diagnostic entity: Acute Suicidal Affective Disturbance (ASAD)
Tucker, R. P., Michaels, M. S., Rogers, M. L., Wingate, L. R., & Joiner, T. E. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.07.049 · Cited by 100 · cited 2× · see citing works
“, 2016; Wolfe-Clark & Bryan, 2017), and sleep disruption has been conceptualized as a manifestation of the over-arousal characteristic of this period of acute suicide risk (Ribeiro et al., 2015; Rogers et al., 2016; Tucker et al., 2016).”
BackgroundWenzel, A., Berchick, E. R., Tenhave, T., Halberstadt, S., Brown, G. K., & Beck, A. T. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2011.03.006 · Cited by 99 · cited 1× · see citing works
“analysis (Bredemeier & Miller, 2015; Franklin et al., 2017; Wenzel et al., 2011), thus the pattern found in the current review of median follow-up lengths increasing substantially with severity of STB.”
A prospective study of risk factors for traumatic deaths in a retirement community
Ross, R. K., Bernstein, L., Trent, L. S., Henderson, B. E., & Paganini‐Hill, A. (1990) · Preventive Medicine · doi:10.1016/0091-7435(90)90032-f · Cited by 93 · see citing works
Risk factors for suicidal thoughts in adolescence-a prospective cohort study: the Young-HUNT study
Strandheim, A., Bjerkeset, O. A., Gunnell, D., Bjørnelv, S., Holmen, T. L., & Bentzen, N. (2014) · BMJ Open · doi:10.1136/bmjopen-2014-005867 · Cited by 82 · see citing works
Sleep and suicide: an analysis of a cohort of 394,000 Taiwanese adults
Gunnell, D., Chang, S.-S., Tsai, M. K., Tsao, C. K., & Wen, C. P. (2013) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-013-0675-1 · Cited by 80 · see citing works
Cha, C. B., Tezanos, K. M., Peros, O. M., Ng, M. Y., Ribeiro, J. D., Nock, M. K., & Franklin, J. C. (2018) · Suicide and Life-Threatening Behavior · doi:10.1111/sltb.12344 · Cited by 77 · cited 1× · see citing works
“These findings are generally consistent with those in a recent systematic review of reporting practices of sample characteristics in the suicide literature (Cha et al., 2018).”
ResultPredicting imminent suicidal thoughts and nonfatal attempts: The role of complexity
Ribeiro, J. D., Huang, X., Fox, K. R., Walsh, C. G., & Linthicum, K. P. (2019) · Clinical Psychological Science · doi:10.1177/2167702619838464 · Cited by 75 · see citing works
Wang, H. E., Campbell‐Sills, L., Kessler, R. C., Sun, X., Heeringa, S. G., Nock, M. K., Ursano, R. J., Jain, S., & Stein, M. B. (2018) · SLEEP · doi:10.1093/sleep/zsy229 · Cited by 74 · cited 1× · see citing works
“This resulted in additional data required for meta-analysis being obtained from the authors of three studies (Kivelä et al., 2019; Littlewood et al., 2019; Wang et al., 2019).”
MethodA 6-year longitudinal study of predictors for suicide attempts in major depressive disorder
Eikelenboom, M., Beekman, A. T. F., Penninx, B. W. J. H., & Smit, J. H. (2018) · Psychological Medicine · doi:10.1017/s0033291718001423 · Cited by 72 · see citing works
Nightmares Are Associated With Future Suicide Attempt and Non-Suicidal Self-Injury in Adolescents
Liu, X., Liu, Z., Chen, R.-H., Cheng, X.-Z., Bo, Q.-G., Wang, Z.-Y., Yang, Y., Fan, F., & Jia, C.-X. (2019) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.18m12181 · Cited by 65 · see citing works
Vande Voort, J. L., Ballard, E. D., Luckenbaugh, D. A., Bernert, R. A., Richards, E. M., Niciu, M. J., Park, L. T., Machado-Vieira, R., Duncan, W. C., & Zarate, C. A. (2017) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.15m10440 · Cited by 65 · see citing works
Insomnia and inflammation: A two hit model of depression risk and prevention
Irwin, M. R., & Piber, D. (2018) · World Psychiatry · doi:10.1002/wps.20556 · Cited by 65 · see citing works
Sokero, P., Eerola, M., Rytsälä, H. J., Melartin, T. K., Leskelä, U. S., Lestelä-Mielonen, P. S., & Isometsä, E. T. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.04.028 · Cited by 64 · cited 1× · see citing works
“This is an important consideration because even among traditionally high-risk populations, the majority of individuals do not engage in suicidal behavior (American Psychiatric Association, 2004; Lau et al., 2004; Liu et al., 2012; Nock et al., 2008; Sokero et al., 2006).”
BackgroundBryan, C. J., Gonzales, J., Rudd, M. D., Bryan, A. O., Clemans, T. A., Ray-Sannerud, B. N., Wertenberger, E. G., Leeson, B., Heron, E. A., Morrow, C. E., et al. (2015) · Depression and Anxiety · doi:10.1002/da.22383 · Cited by 61 · see citing works
Identifying adolescents at highly elevated risk for suicidal behavior in the emergency department
King, C. A., Berona, J., Czyz, E., Horwitz, A. G., & Gipson, P. Y. (2015) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2014.0049 · Cited by 54 · see citing works
Longitudinal course of suicidal ideation and predictors of its persistence – A NESDA study
Kivelä, L. M. M., Krause-Utz, A., Mouthaan, J., Schoorl, M., de Kleine, R. A., Elzinga, B. M., Eikelenboom, M., Penninx, B. W. J. H., van der Does, W. A. J., & Antypa, N. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.07.042 · Cited by 53 · cited 1× · see citing works
“This resulted in additional data required for meta-analysis being obtained from the authors of three studies (Kivelä et al., 2019; Littlewood et al., 2019; Wang et al., 2019).”
MethodRibeiro, J. D., Yen, S., Joiner, T., & Siegler, I. C. (2015) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.07.037 · Cited by 48 · cited 1× · see citing works
“, 2016; Wolfe-Clark & Bryan, 2017), and sleep disruption has been conceptualized as a manifestation of the over-arousal characteristic of this period of acute suicide risk (Ribeiro et al., 2015; Rogers et al., 2016; Tucker et al., 2016).”
BackgroundSuicidal ideation in elderly Korean population: a two-year longitudinal study
Kang, H., Stewart, R. J., Jeong, B.-O., Kim, S., Bae, K., Kim, S., Kim, J., Shin, I., & Yoon, J. (2013) · International Psychogeriatrics · doi:10.1017/s1041610213001634 · Cited by 48 · see citing works
Integrating Two Theoretical Models to Understand and Prevent Military and Veteran Suicide
Wolfe-Clark, A. L., & Bryan, C. J. (2016) · Armed Forces & Society · doi:10.1177/0095327x16646645 · Cited by 41 · see citing works
Zuromski, K. L., Cero, I., & Witte, T. K. (2017) · Journal of Abnormal Psychology · doi:10.1037/abn0000282 · Cited by 37 · see citing works
Hartwig, E. M., Rufino, K. A., Palmer, C. A., Shepard, C. A., Alfano, C. A., Schanzer, B., Mathew, S. J., & Patriquin, M. A. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.03.069 · Cited by 33 · see citing works
Stange, J. P., Kleiman, E. M., Sylvia, L. G., Magalhães, P. V. D. S., Berk, M., Nierenberg, A. A., & Deckersbach, T. (2016) · Depression and Anxiety · doi:10.1002/da.22464 · Cited by 33 · see citing works
The critical need for help-seeking controls in clinical high-risk research
Millman, Z. B., Gold, J. M., Mittal, V. A., & Schiffman, J. (2019) · Clinical Psychological Science · doi:10.1177/2167702619855660 · Cited by 33 · see citing works
Allan, N. P., Conner, K. R., Pigeon, W. R., Grös, D. F., Salami, T. K., & Stecker, T. A. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.03.009 · Cited by 32 · see citing works
Na, E. J., Lee, H., Myung, W., D, M. F. M., Mischoulon, D., Paik, J., Hong, J. P., Choi, K. W., Kim, H., & Jeon, H. J. (2019) · Psychiatry Investigation · doi:10.30773/pi.2019.02.19 · Cited by 31 · see citing works
A comparison of delay discounting among substance users with and without suicide attempt history
Liu, R. T., Vassileva, J., Gonzalez, R., & Martin, E. M. (2012) · Psychology of Addictive Behaviors · doi:10.1037/a0027384 · Cited by 30 · cited 1× · see citing works
“This is an important consideration because even among traditionally high-risk populations, the majority of individuals do not engage in suicidal behavior (American Psychiatric Association, 2004; Lau et al., 2004; Liu et al., 2012; Nock et al., 2008; Sokero et al., 2006).”
BackgroundSelf-citationPredicting suicide in older adults – a community-based cohort study in Taipei City, Taiwan
Hung, G. C., Kwok, C.-L., Yip, P. S. F., Gunnell, D., & Chen, Y. (2014) · Journal of Affective Disorders · doi:10.1016/j.jad.2014.09.037 · Cited by 30 · see citing works
Presence and Persistence of Sleep-Related Symptoms and Suicidal Ideation in Psychiatric Inpatients
Nadorff, M. R., Ellis, T. E., Allen, J. G., Winer, E. S., & Herrera, S. (2014) · Crisis · doi:10.1027/0227-5910/a000279 · Cited by 30 · see citing works
Hom, M. A., Stanley, I. H., Chu, C., Sanabria, M., Christensen, K., Albury, E. A., Rogers, M. L., & Joiner, T. E. (2019) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.7570 · Cited by 29 · see citing works
Recent advances in psychoneuroimmunology: Inflammation in psychiatric disorders
Debnath, M., Doyle, K., Langan, C., McDonald, C., Leonard, B., & Cannon, D. (2011) · Translational Neuroscience · doi:10.2478/s13380-011-0019-0 · Cited by 28 · cited 1× · see citing works
“communicating through the vagus nerve and microglial activation (Debnath et al., 2011), and abnormal elevations in these pro-inflammatory cytokines have been identified in the cerebrospinal fluid and post-mortem brain samples of suicidal individuals (Black & Miller, 2015).”
BackgroundPredicting Suicidal Ideation in College Students with Mental Health Screening Questionnaires
Shim, G., & Jeong, B. (2018) · Psychiatry Investigation · doi:10.30773/pi.2018.08.21.3 · Cited by 24 · see citing works
Rogers, M. L., Tucker, R. P., Law, K. C., Michaels, M. S., Anestis, M. D., & Joiner, T. E. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.12.014 · Cited by 24 · cited 1× · see citing works
“, 2016; Wolfe-Clark & Bryan, 2017), and sleep disruption has been conceptualized as a manifestation of the over-arousal characteristic of this period of acute suicide risk (Ribeiro et al., 2015; Rogers et al., 2016; Tucker et al., 2016).”
BackgroundSuicide in Male Alcoholics with Peptic Ulcers
Berglund, M. (1986) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1986.tb05158.x · Cited by 17 · see citing works
Sleep complaints associated with wish to die after a suicide crisis—an exploratory study
Mîrșu-Păun, A., Jaussent, I., Komar, G., Courtet, P., & López‐Castromán, J. (2017) · Journal of Sleep Research · doi:10.1111/jsr.12537 · Cited by 15 · cited 5× · see citing works
“Furthermore, sleep disturbance is prominently featured as a warning sign (i.e., precipitating risk factor) for STBs by the American Association of Suicidology (American Association of Suicidology, 2019), the American Foundation for Suicide Prevention (American Foundation for Suicide Prevention, 2019), the National Ins…”
BackgroundInfluentialLau, J. W., Stewart, S. M., King, J. D., Kennard, B. D., & Emslie, G. J. (2019) · Psychiatry Research · doi:10.1016/j.psychres.2019.112527 · Cited by 14 · see citing works
Psychological Symptoms in Late Adolescence and Long‐Term Risk of Suicide and Suicide Attempt
Hogstedt, C., Forsell, Y., Hemmingsson, T., Lundberg, I., & Lundin, A. (2017) · Suicide and Life-Threatening Behavior · doi:10.1111/sltb.12362 · Cited by 13 · see citing works
Philip III and the restoration of Spanish government, 1598–16031
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Hom, M. A., Duffy, M. E., Rogers, M. L., Hanson, J. E., Gutierrez, P. M., & Joiner, T. E. (2018) · Psychological Medicine · doi:10.1017/s0033291718003124 · Cited by 9 · see citing works
Anxiety and Suicide in Depression
Roy, A. (1993) · The Canadian Journal of Psychiatry · doi:10.1177/070674379303801018 · Cited by 2 · see citing works
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Sleep Deprivation and Insomnia in Adolescence: Implications for Mental Health
Uccella, S., Cordani, R., Salfi, F., Gorgoni, M., Scarpelli, S., Gemignani, A., Geoffroy, P. A., Gennaro, L. D., Palagini, L., Ferrara, M., et al. (2023) · Brain Sciences · doi:10.3390/brainsci13040569 · Cited by 153 · see citing works
“Recent findings have shown that alterations in sleep and circadian rhythms are also predictive factors of non-suicidal self-injuries (NSSIs), suicidal ideation (SI), and suicidal attempts (SA) [69].”
BackgroundCoppersmith, D. D. L., Dempsey, W., Kleiman, E. M., Bentley, K. H., Murphy, S. A., & Nock, M. K. (2022) · Psychiatry · doi:10.1080/00332747.2022.2092828 · Cited by 130 · see citing works
“For example, emotion dysregulation, sleep, and social connectedness are dynamic, modifiable constructs that have been associated with STB risk (Baumeister, 1990; C. L. Dempsey et al., 2021; Liu et al., 2020).”
BackgroundWu, T., Zou, Y., Xu, K. D., Jiang, X. R., Zhou, M., Zhang, S. B., & Song, C. (2023) · Public Health · doi:10.1016/j.puhe.2022.11.021 · Cited by 107 · see citing works
Hamilton, J. L., Tsypes, A., Zelazny, J., Sewall, C. J. R., Rode, N., Merranko, J., Brent, D. A., Goldstein, T. R., & Franzen, P. L. (2023) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13651 · Cited by 71 · see citing works
Self-citationWang, D., Ross, B., Zhou, X., Meng, D., Zhu, Z., Zhao, J., Fan, F., & Liu, X. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.09.038 · Cited by 68 · see citing works
The use of advanced technology and statistical methods to predict and prevent suicide
Kleiman, E. M., Glenn, C. R., & Liu, R. T. (2023) · Nature Reviews Psychology · doi:10.1038/s44159-023-00175-y · Cited by 63 · see citing works
“The link between subjectively assessed poor sleep and increased risk for suicide 65–67 (including studies that used EMA or daily diary assessments of subjective sleep quality 56,58,59 ) provides a strong foundation for work that explores whether objective measures of sleep are associated with…”
BackgroundSelf-citationSutar, R. F., Kumar, A., & Yadav, V. (2023) · Psychiatry Research · doi:10.1016/j.psychres.2023.115492 · Cited by 55 · see citing works
Glenn, C. R., Kleiman, E. M., Kearns, J. C., Boatman, A. E., Conwell, Y., Alpert‐Gillis, L. J., & Pigeon, W. R. (2021) · Development and Psychopathology · doi:10.1017/s0954579421000699 · Cited by 45 · see citing works
“…potential affective (Baum et al., 2014; Ben-Zeev, Young, & Depp, 2012), cognitive (De Bruin, van Run, Staaks, & Meijer, 2017; Keilp et al., 2001), and inflammatory mechanisms (Black & Miller, 2015; Irwin & Piber, 2018) that may mediate this association (Kearns et al., 2020; Liu et al., 2020).”
BackgroundResultInfluentialQi, X., Malone, S. K., Pei, Y., Zhu, Z., & Wu, B. (2023) · Psychiatry Research · doi:10.1016/j.psychres.2023.115266 · Cited by 47 · see citing works
Romier, A., Maruani, J., López‐Castromán, J., Palagini, L., Serafini, G., Lejoyeux, M., d’Ortho, M., & Geoffroy, P. A. (2023) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2023.101760 · Cited by 44 · see citing works
Self-Referential Processing and Depression: A Systematic Review and Meta-Analysis
Collins, A. C., & Winer, E. S. (2023) · Clinical Psychological Science · doi:10.1177/21677026231190390 · Cited by 45 · see citing works
“As done in previous work (Liu, Bettis, & Burke, 2020; Liu, Steele, et al., 2020), we conducted additional moderator analyses to examine potential causes of heterogeneity (i.e., age of depressed group, gender [% female] of depressed group, recall delay [in minutes], and study bias) when our results…”
Chan, C. S., Wong, C. Y.-F., Yu, B. Y., Hui, V. K., Ho, F. Y., & Cuijpers, P. J. (2021) · Psychological Medicine · doi:10.1017/s0033291721003421 · Cited by 42 · see citing works
Sleep, Sleep Disorders, and Mental Health: A Narrative Review
Howarth, N. E., & Miller, M. A. (2024) · Heart and Mind · doi:10.4103/hm.hm-d-24-00030 · Cited by 46 · see citing works
Sleep irregularity and nonsuicidal self-injurious urges and behaviors
Burke, T. A., Hamilton, J. L., Seigel, D., Kautz, M. M., Liu, R. T., Alloy, L. B., & Barker, D. (2022) · SLEEP · doi:10.1093/sleep/zsac084 · Cited by 36 · see citing works
Self-citationHamilton, J. L., Hutchinson, E., Evankovich, M. R., Ladouceur, C. D., & Silk, J. S. (2022) · Journal of Sleep Research · doi:10.1111/jsr.13611 · Cited by 38 · see citing works
“Given that sleep is a major risk factor for depression and suicidal thoughts and behaviors (Liu et al., 2020), it is critical to identify modifiable risk factors for sleep among adolescent girls, especially during the high-stress period of the pandemic (Racine et al., 2021).”
Self-citationSocial and Circadian Rhythm Dysregulation and Suicide: A Systematic Review and Meta-Analysis
Walsh, R., Maddox, M. A., Smith, L., Liu, R. T., & Alloy, L. B. (2024) · Neuroscience and Biobehavioral Reviews · doi:10.1016/j.neubiorev.2024.105560 · Cited by 28 · see citing works
Self-citationKönig, L., Zitzmann, S., Fütterer, T., Campos, D., Scherer, R., & Hecht, M. (2024) · Research Synthesis Methods · doi:10.1002/jrsm.1762 · Cited by 33 · see citing works
Specific aspects of sleep disturbance associated with suicidal thoughts and attempts
Batterham, P. J., Werner‐Seidler, A., Calear, A. L., McCallum, S. M., & Gulliver, A. (2020) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.12.150 · Cited by 29 · see citing works
Examining sleep disturbance components as near-term predictors of suicide ideation in daily life
Cox, R. C., Brown, S. L., Chalmers, B. N., & Scott, L. N. (2023) · Psychiatry Research · doi:10.1016/j.psychres.2023.115323 · Cited by 25 · see citing works
Pei, C., Fan, C., Luo, H., Bai, A., Ni, S., Luo, M., Huang, J., Zhou, Y., & Huo, L. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.05.095 · Cited by 26 · see citing works
Flannigan, K., McMorris, C. A., Ewasiuk, A., Badry, D., Mela, M., Gibbard, W. B., Unsworth, K., Cook, J. L., & Harding, K. D. (2021) · The Canadian Journal of Psychiatry · doi:10.1177/07067437211053288 · Cited by 24 · see citing works
Miller, B. J., & McCall, W. V. (2021) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.9646 · Cited by 24 · see citing works
“17 – 21 However, no previous studies have specifically investigated whether improvement in insomnia is associated with decreased SIB during treatment with either clozapine or lithium.”
InfluentialAssociation between hospital-diagnosed sleep disorders and suicide: a nationwide cohort study
Høier, N. K., Madsen, T., Spira, A. P., Hawton, K. E., Benros, M. E., Nordentoft, M., & Erlangsen, A. (2022) · SLEEP · doi:10.1093/sleep/zsac069 · Cited by 25 · see citing works
Sleep, hopelessness, and suicidal ideation: An ecological momentary assessment and actigraphy study
Kivelä, L. M. M., van der Does, W. A. J., & Antypa, N. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.06.039 · Cited by 23 · see citing works
Que, J., Shi, L., Yan, W., Chen, S., Wu, P., Sun, S., Yuan, K., Liu, Z., Zhu, Z., Fan, J.-Y., et al. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.02.033 · Cited by 23 · see citing works
Probing the digital exposome: associations of social media use patterns with youth mental health
Pagliaccio, D., Tran, K. T., Visoki, E., DiDomenico, G. E., Auerbach, R. P., & Barzilay, R. (2024) · NPP—Digital Psychiatry and Neuroscience · doi:10.1038/s44277-024-00006-9 · Cited by 23 · see citing works
“Code for all analyses can be found at https://github.com/barzilab1/ABCD_digital_exposome.”
Yu, Z., Zhu, X., & Li, Y. (2024) · BMC Public Health · doi:10.1186/s12889-024-19191-5 · Cited by 23 · see citing works
“There are small-to-medium to medium effect sizes for sleep disturbance and suicidal ideation, attempts, and death (see [21], for meta-analysis).”
BackgroundGoldstein, T., & Franzen, P. (2022) · Current Sleep Medicine Reports · doi:10.1007/s40675-022-00222-9 · Cited by 27 · see citing works
McCarthy, E., DeViva, J. C., Southwick, S. M., & Pietrzak, R. H. (2021) · Journal of Sleep Research · doi:10.1111/jsr.13447 · Cited by 20 · see citing works
Fetter, A. K., Wiglesworth, A., Rey, L. F., Azarani, M., Chicken, M. L. P., Young, A. R., Riegelman, A., & Gone, J. P. (2022) · Clinical Psychological Science · doi:10.1177/21677026221126732 · Cited by 19 · see citing works
“Sleep problems, which have been a large focus in the general suicide literature (Liu et al., 2020), were examined in only one study among youths (Farrell, 2013).”
BackgroundCoppersmith, D. D. L., Dempsey, W., Kleiman, E. M., et al. (2021) · doi:10.31234/osf.io/eg9fx · Cited by 18 · see citing works
Sleep and next-day negative affect and suicidal ideation in borderline personality disorder.
Kaurin, A., Hisler, G. C., Dombrovski, A. Y., Hallquist, M. N., & Wright, A. G. C. (2021) · Personality Disorders Theory Research and Treatment · doi:10.1037/per0000496 · Cited by 21 · see citing works
Longitude-based time zone partitions and rates of suicide
Reis, D. J., Yen, P., Tizenberg, B., Gottipati, A., Postolache, S. Y., Riggs, D. D., Nance, M., Dagdag, A., Plater, L. Y., Federline, A., et al. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.07.080 · Cited by 18 · see citing works
Chen, X., Dai, Z., Fu, J., Si, M., Jing, S., Wu, Y., Wang, H., Huang, Y., Cui, D., Qu, Y., et al. (2023) · QJM · doi:10.1093/qjmed/hcad083 · Cited by 19 · see citing works
Liu, Z., Jia, C.-X., & Liu, X. (2022) · SLEEP · doi:10.1093/sleep/zsac221 · Cited by 19 · see citing works
Sun, L., Li, K., Zhang, Y., & Zhang, L. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.10.126 · Cited by 16 · see citing works
Kirschbaum‐Lesch, I., Holtmann, M. H., & Legenbauer, T. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.622833 · Cited by 19 · see citing works
Saulnier, K. G., Singh, R., Lenker, K. P., Calhoun, S. L., He, F., Liao, D., Vgontzas, A. N., Bixler, E. O., & Fernández‐Mendoza, J. (2022) · Sleep Health · doi:10.1016/j.sleh.2022.05.004 · Cited by 17 · see citing works
Misiak, B., Pytel, A., & Stańczykiewicz, B. (2025) · Psychological Medicine · doi:10.1017/s0033291725000261 · Cited by 18 · see citing works
“Nevertheless, it is needed to note that both sleep disturbance, especially insomnia, and PLEs have been associated with suicide risk as demonstrated by previous meta-analyses (Liu et al. 2020; Yates et al. 2019).”
Mournet, A. M., & Kleiman, E. M. (2024) · Journal of Sleep Research · doi:10.1111/jsr.14133 · Cited by 16 · see citing works
Lü, X., Lai, S., Luo, A., Huang, X., Wang, Y., Zhang, Y., He, J., Chen, G., Zhong, S., & Jia, Y. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.04.132 · Cited by 14 · see citing works
Landa–Blanco, M., Romero, K., Caballero, I., Gálvez-Pineda, E., Fúnes-Henríquez, M. J., & Romero, R. (2024) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1352889 · Cited by 18 · see citing works
Bu, L., Wang, D., Fan, Y., Ye, H., Liu, W., & Fan, F. (2024) · SLEEP · doi:10.1093/sleep/zsae013 · Cited by 14 · see citing works
Liu, X., Yang, Y., Liu, Z., & Jia, C.-X. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.01.153 · Cited by 14 · see citing works
Lv, D., Ou, Y., Xiao, D., Li, H., Liu, F., Li, P., Zhao, J., & Guo, W. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-05305-7 · Cited by 11 · see citing works
“Meta-analyses have shown that SD is positively correlated with the over-all severity of MDD and its impact on quality of life [6, 7].”
BackgroundKhazaie, H., Najafi, F., Chehri, A., Rahimi‐Movaghar, A., Amin‐Esmaeili, M., Moradinazar, M., Zakiei, A., Pasdar, Y., Brühl, A. B., Brand, S., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12082821 · Cited by 13 · see citing works
“The latter was observed among individuals with major depressive disorder, specifically [36], and generally among individuals with psychiatric diagnoses [37], among different cohort studies [38] including adolescents [39–42], and in longitudinal studies [43].”
BackgroundAdvances in Research on Adolescent Suicide and a High Priority Agenda for Future Research
Clayton, M. G., Pollak, O. H., Owens, S., Miller, A. B., & Prinstein, M. J. (2021) · Journal of Research on Adolescence · doi:10.1111/jora.12614 · Cited by 11 · see citing works
“A recent meta-analysis of adult-and adolescent-based longitudinal studies found evidence for prospective associations between sleep problems and STBs, with small-to-medium effect sizes (Liu et al., 2020).”
The Night and Day Challenge of Sleep Disorders and Insomnia: A Narrative Review.
San, L., & Arranz, B. (2024) · Actas Españolas de Psiquiatría · Cited by 10 · see citing works
Dewa, L. H., Broyd, J. G., Hira, R., Dudley, A., Hafferty, J. D., Bates, R., & Aylin, P. P. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-05437-w · Cited by 10 · see citing works
“This was despite the evidence showing the paradoxical impact of poor sleep being linked to subsequent aggression [3, 4] and suicide risk [18, 19] in line with other studies [20].”
Rogers, E. N., Gresswell, D. M., & Durrant, S. J. (2023) · Schizophrenia Research · doi:10.1016/j.schres.2023.10.010 · Cited by 11 · see citing works
“…the importance of recognising sleep disturbance as a long-term predictor of suicidal ideation and behaviours in both adults (Liu et al., 2020a,Liu et al., 2020b) and adolescents (Lee et al., 2012) with work indicating a U-shaped dose-response relationship between sleep duration and…”
Tadros, M., Li, S. H., Upton, E. L., Newby, J. M., & Werner‐Seidler, A. (2023) · JMIR Human Factors · doi:10.2196/44145 · Cited by 11 · see citing works
“It can also heighten the risk of suicidal thoughts and behaviors [16], worsen comorbid mental health conditions, increase the likelihood of relapse [17], prolong the course of depression [18,19], and blunt treatment effects [20].”
BackgroundFarah, N., Obeïd, S., Malaeb, D. N., Haddad, C., Fekih‐Romdhane, F., & Hallit, S. R. (2023) · BMC Psychiatry · doi:10.1186/s12888-023-04778-w · Cited by 11 · see citing works
“In particular, increasing evidence from longitudinal studies evidenced a significant and positive relationship between PLEs and suicidal ideation and behavior (SIB) [11–14].”
BackgroundInfluentialYu, Z., & Zhu, X. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.02.093 · Cited by 13 · see citing works
Tubbs, A., Taneja, K., Ghani, S. B., Nadorff, M. R., Drapeau, C. W., Karp, J., Fernandez, F., Perlis, M., & Grandner, M. (2023) · Journal of American College Health · doi:10.1080/07448481.2022.2155828 · Cited by 14 · see citing works
“…in sleep duration and efficiency to worsening clinical insomnia and nightmares, and these deficits likely raise the risk for future STBs. 23,24 Fortunately, sleep interventions such as cognitive behavioral therapy for insomnia (CBT-I) or imagery rehearsal therapy for nightmares (IRT) have…”
Manasse, S. M., Lampe, E. W., Gillikin, L. M., Trainor, C. M., Abber, S. R., Fitzpatrick, B., Sanchez, H., & Juarascio, A. S. (2022) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-022-01445-z · Cited by 12 · see citing works
“For example, results from two large literature reviews show that short sleep duration and poor sleep quality are prospectively associated with increased negative affect and deficits in emotion regulation [4, 5], both of which are positively associated with engagement in BE and other * Elizabeth W.”
ResultAssociations between treatment with melatonin and suicidal behavior: a nationwide cohort study
Høier, N. K., Madsen, T., Spira, A. P., Hawton, K. E., Jennum, P., Nordentoft, M., & Erlangsen, A. (2022) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.10118 · Cited by 12 · see citing works
Manasse, S. M., Haedt‐Matt, A. A., Smith, K. E., Egbert, A. H., O’Sullivan, K. L., Koren, D., Engel, S. G., & Goldschmidt, A. B. (2022) · European Eating Disorders Review · doi:10.1002/erv.2908 · Cited by 11 · see citing works
Patel, K. K., Kearns, J. C., Foti, D., Pigeon, W. R., Kleiman, E. M., & Glenn, C. R. (2024) · Research on Child and Adolescent Psychopathology · doi:10.1007/s10802-024-01275-w · Cited by 10 · see citing works
“Lastly, although existing research has linked sleep prob - lems and STBs (Kearns et al., 2020; Liu et al., 2020a; Pigeon et al., 2012, 2016), minimal research has focused on explicating the mechanisms underlying this relation, which could inform targets for intervention and prevention of STBs.”
IL-6 predicts non-suicidal self-injury over 3 months in high-risk adolescents
Bai, S., Asarnow, J. R., Babeva, K. N., & Irwin, M. R. (2024) · BJPsych Open · doi:10.1192/bjo.2023.656 · Cited by 10 · see citing works
“25,26 Consistent with past studies, we hypothesised that higher levels of inflammation would predict higher levels of suicidal ideation, depression symptoms and poorer sleep.”
BackgroundQiao, X., Shi, X., Chen, X., & Ya, Z. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.07.108 · Cited by 10 · see citing works
A Suicide-Specific Diagnosis – The Case Against
Berman, A. L., & Silverman, M. M. (2023) · Crisis · doi:10.1027/0227-5910/a000912 · Cited by 11 · see citing works
Self-Referential Processing and Depression: A Systematic Review and Meta-AnalysisPreprint
Collins, A. C., & Winer, E. S. (2022) · doi:10.31219/osf.io/u7fw5 · Cited by 8 · see citing works
Dosogne, M., Wacquier, B., Faker, M. A., Willame, H., Point, C., Loas, G., & Hein, M. (2021) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2021.11.034 · Cited by 10 · see citing works
Nightmares and insomnia within the acute aftermath of trauma prospectively predict suicidal ideation
Reffi, A. N., Kalmbach, D. A., Cheng, P., Moore, D. A., Jennings, M. B., Mahr, G., Seymour, G. M., Jankowiak, L., & Drake, C. L. (2025) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.11744 · Cited by 9 · see citing works
“6 By contrast, most longitudinal studies on sleep and suicide utilize longer-term follow-ups (median = 10.5 months 6 ) that are more conducive to examining predictors of delayed risk for suicide.”
InfluentialGarcia, M. A., & Cooper, T. V. (2024) · Psychiatric Quarterly · doi:10.1007/s11126-024-10085-8 · Cited by 12 · see citing works
“…[ 38], and thus poor sleep health (e.g., short sleep duration, poor sleep quality) is associated with multiple adverse outcomes including: poor mental health [ 39, 40 ], impaired decision making, loss of motivation [ 41 ], obesity, diabetes [ 42], heart disease [ 43 ], and suicide risk [ 44].”
Shepard, C. A., Rufino, K. A., Lee, J., Tran, T. M., Paddock, K., Wu, C., Oldham, J. M., Mathew, S. J., & Patriquin, M. A. (2022) · Behavioral Sleep Medicine · doi:10.1080/15402002.2022.2050724 · Cited by 9 · see citing works
“However, there are well-established risk factors of suicide risk including prior suicidal thoughts (Baca-Garcia et al., 2011; Park et al., 2017; R. T. Liu et al., 2020), hopelessness (Ribeiro et al., 2018), and nonsuicidal self-injury (Klonksy et al., 2013; Whitlock et al., 2013).”
BackgroundPalagini, L., Arango, C., Bassetti, C. L., Bastien, C., Geoffroy, P. A., Elder, G. J., Ellis, J. G., Hedner, J. A., Khullar, A., Nobili, L., et al. (2025) · Sleep Medicine · doi:10.1016/j.sleep.2025.106763 · Cited by 12 · see citing works
“…bidirectional relationship between insomnia and psychiatric disorders, including depression and suicide risk, the prioritization of insomnia in public health policies may also represent a strategic step toward suicide prevention and overall mental health improvement [38,39] (Tables 2 and 3).”
Dewa, L. H., Pappa, S., Greene, T., Cooke, J., Mitchell, L., Hadley, M., Simplicio, M. C. D., Woodcock, T. M., & Aylin, P. P. (2022) · JMIR Research Protocols · doi:10.2196/33817 · Cited by 5 · see citing works
“The temporal nature of the relationship between sleep disturbance and suicidality was the focus of the most recent systematic review [10].”
BackgroundLamontagne, S. J., Ballard, E. D., & Zarate, C. A. (2022) · Neurobiology of Stress · doi:10.1016/j.ynstr.2022.100450 · Cited by 9 · see citing works
Häberling, I. S., Preisig, M., Emery, S., Baumgartner, N., Albermann, M., Strumberger, M. A., Schmeck, K., Wöckel, L., Erb, S., Rhiner, B., et al. (2025) · Frontiers in Child and Adolescent Psychiatry · doi:10.3389/frcha.2025.1510961 · Cited by 7 · see citing works
“It is possible that sleep dysregulation affects executive control (80), increasing the risk for suicidal behavior.”
Walsh, R. F. L., Maddox, M. A., Smith, L. T., Olino, T. M., Zee, P. C., Nusslock, R., & Alloy, L. B. (2025) · Journal of Sleep Research · doi:10.1111/jsr.14468 · Cited by 9 · see citing works
“Further, insofar as sleep disturbances have been touted as a potentially modifiable risk factor to improve health (Franzen & Buysse, 2008; Liu et al., 2020), identifying the specific aspect of disturbed sleep to target for intervention is paramount.”
Zhang, X., Zhang, Y., Bu, L., Li, H., Ye, H., Wang, D., & Fan, F. (2024) · Sleep Medicine · doi:10.1016/j.sleep.2024.10.031 · Cited by 8 · see citing works
Dewa, L. H., Thibaut, B., Pattison, N. A., Campbell, S. J., Woodcock, T. M., Aylin, P. P., & Archer, S. (2024) · SLEEP Advances · doi:10.1093/sleepadvances/zpae003 · Cited by 7 · see citing works
“Moreover, there is a well-recognized relationship between sleep disturbance and suicidal ideation, behavior, and deaths due to suicide [7–9].”
BackgroundLiu, X., Yang, Y., Liu, Z., & Jia, C.-X. (2023) · SLEEP · doi:10.1093/sleep/zsad121 · Cited by 7 · see citing works
Cruz-Sanabria, F., Violi, M., Bazzani, A., Bruno, S., Massoni, L., Bertelloni, C., Dell'Oste, V., Frumento, P., Faraguna, U., Dell'Osso, L., et al. (2023) · CNS Spectrums · doi:10.1017/s1092852923001207 · Cited by 5 · see citing works
“68 Considering the evidence in the literature and our results, further studies could explore whether, in ETs, objective measurements of sleep duration, sleep regularity, and sleep-phase may mediate the appearance of mood disturbances, including symptoms related to suicidal ideation in both clinical…”
BackgroundZemestani, M., Abdolmaleki, S., McGrew, S. J., & Vujanovic, A. A. (2023) · Archives of Suicide Research · doi:10.1080/13811118.2023.2190366 · Cited by 8 · see citing works
“Imperative to the development of prevention plans for suicide is the identification of modifiable risk factors (Bishop, Walsh, Ashrafioun, Lavigne, & Pigeon, 2020; Hallard, Wells, Aadahl, Emsley, & Pratt, 2021; Liu et al., 2020).”
BackgroundBradford, D. R. R., Biello, S. M., & Russell, K. (2021) · Archives of Suicide Research · doi:10.1080/13811118.2021.1885537 · Cited by 8 · see citing works
“Insomnia has been identified as an independent risk factor for SIBs (Becker, Dvorsky, Holdaway, & Luebbe, 2018; Bernert, Hom, Iwata, & Joiner, 2017; Liu et al., 2020; Nadorff, Nazem, & Fiske, 2011; Pigeon, Pinquart, & Conner, 2012).”
Teresi, G. I., Merranko, J. A., Porta, G., Bero, K., Poling, K. D., Brent, D. A., & Goldstein, T. R. (2024) · Suicide and Life-Threatening Behavior · doi:10.1111/sltb.13141 · Cited by 6 · see citing works
“…conclusions from recent meta-analyses demonstrating small prospective effects between sleep and mood in youth (Marino et al., 2021) and small- to-medium prospective effects be-tween sleep and suicide risk in all ages (Liu et al., 2020), clinical implications of these findings may be considerable.”
Sadeghi-Bahmani, D., Rigotti, V., Stanga, Z., Lang, U. E., Blais, R. K., Kelley, M. L., & Brand, S. (2024) · Frontiers in Public Health · doi:10.3389/fpubh.2024.1390636 · Cited by 6 · see citing works
McIntyre, R. S., Wong, S., Kwan, A. T. H., Rhee, T. G., Teopiz, K. M., Ho, R., Cao, B., Mansur, R. B., Rosenblat, J. D., & Le, G. H. (2024) · Expert Opinion on Drug Safety · doi:10.1080/14740338.2024.2361300 · Cited by 8 · see citing works
“In addition to the aforementioned risk, chronic insomnia is a risk factor for suicidality [6].”
Huang, J., Yang, Z., Wang, Q., Liu, J., Xie, W., & Sun, Y. (2024) · BMC Psychiatry · doi:10.1186/s12888-024-05700-8 · Cited by 7 · see citing works
Tsai, Y., Chuang, T.-J., Mudiyanselage, S. P. K., Ku, H., Wu, Y., Li, C., & Ko, N. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.10.045 · Cited by 6 · see citing works
Zhang, J., Mi, L., Zhao, J., Chen, H., Wang, D., Ma, Z., & Fan, F. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.830383 · Cited by 6 · see citing works
Age Moderates the Relation between Sleep Problems and Suicide Risk
Bolstad, C. J., Cui, R., Fiske, A., & Nadorff, M. R. (2022) · Clinical Gerontologist · doi:10.1080/07317115.2022.2044951 · Cited by 5 · see citing works
“Sleep problems have been well established as a major risk factor for psychiatric illness and suicide in adults and older adults (Liu et al., 2020; Nadorff, Drapeau, & Pigeon, 2018).”
BackgroundUsing Psychologically-Informed Priors for Suicide Prediction in the CLPsych 2021 Shared Task
Gamoran, A., Kaplan, Y., Orr, R. I., Simchon, A., & Gilead, M. (2021) · Workshop on Computational Linguistics and Clinical Psychology (CLPsych) · doi:10.18653/v1/2021.clpsych-1.12 · Cited by 7 · see citing works
“The proportion of tweets written late at night (23:00 – 5:00) was measured, as sleep disorders are re-lated to depression and suicidal ideation (Liu et al., 2020).”
MethodJiang, Y., & Jiang, C.-Y. (2025) · Acta Psychologica · doi:10.1016/j.actpsy.2025.105504 · Cited by 7 · see citing works
The Intersection of sleep disturbance and suicidal behavior among older Adults: A systematic review
Saeed, F., Rashedi, V., Kashaninasab, F., Khoozan, M., Moghadam, A. P., Hussaini, S. S., Validabady, Z., & Shoib, S. (2025) · Sleep Medicine · doi:10.1016/j.sleep.2025.106557 · Cited by 5 · see citing works
Influence of Pelvic Floor Disorders on Sleep Quality in Women
Peinado‐Molina, R. A., Martínez‐Vázquez, S., Hernández‐Martínez, A., & Martínez‐Galiano, J. M. (2024) · Journal of Personalized Medicine · doi:10.3390/jpm14030320 · Cited by 6 · see citing works
König, L., Zitzmann, S., Fütterer, T., Campos, D., Scherer, R., & Hecht, M. (2023) · doi:10.31234/osf.io/ybu3w · Cited by 33 · see citing works
Liao, J., Rosenheck, R. A., Sun, B., et al. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.11.072 · Cited by 5 · see citing works
Maity, A., Wang, A. W., Dreier, M. J., Wallace, V., Orchard, F., Schleider, J. L., Loades, M. E., & Hamilton, J. L. (2023) · Clinical Child Psychology and Psychiatry · doi:10.1177/13591045231205475 · Cited by 7 · see citing works
Self-citationBuitron, V., Maron, M. M., Kudinova, A. Y., Thompson, E., Barker, D., & Wolff, J. C. (2023) · Journal of Clinical Psychology · doi:10.1002/jclp.23558 · Cited by 6 · see citing works
Emerging evidence for sleep instability as a risk mechanism for nonsuicidal self-injury
Tubbs, A. S., Fernandez, F., Grandner, M. A., & Perlis, M. L. (2022) · SLEEP · doi:10.1093/sleep/zsac095 · Cited by 5 · see citing works
Warum brauchen wir Leitlinien für Suizidprävention?
Schneider, B., Reif, A., Wagner, B., & Wolfersdorf, M. (2021) · Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz · doi:10.1007/s00103-021-03468-w · Cited by 5 · see citing works
Time to Suicide and Suicide Attempt among Army Enlisted Soldiers’ First Year of Service
Smith, J. D., Schaughency, K. C., Christopher, P., Watkins, E. Y., & Anke, K. M. (2020) · Military Behavioral Health · doi:10.1080/21635781.2020.1860169 · Cited by 5 · see citing works
“Sleep disturbances may also prospectively predict some suicidal behaviors, as well as exasperate other behavioral health conditions (Liu et al., 2020).”
BackgroundKim, A. W. (2024) · American Journal of Human Biology · doi:10.1002/ajhb.24038 · Cited by 5 · see citing works
Wang, Y., Wang, Q., Gong, W., Shang, X., Ruan, J., Liang, W., Lin, Z., & Li, S. (2025) · BMC Public Health · doi:10.1186/s12889-025-23840-8 · Cited by 5 · see citing works
“Sleep disturbances are increasingly recognized as a crucial factor in self-injury and suicide, and they have been identified as prominent warning signals and contributing risk factors by many suicide organizations, such as the National Institute of Mental Health [14].”
InfluentialLoose, T., Perret, L. C., Choi, M., Geoffroy, M., Chon, D., Kim, J., & Ki, M. (2025) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2025.05.014 · Cited by 4 · see citing works
Kim, H., Kwon, S., Park, S., Kang, C., & Kim, H. (2025) · BMC Nursing · doi:10.1186/s12912-025-03432-y · Cited by 4 · see citing works
- Authors
- Liu, R. T., Steele, S. J., Hamilton, J. L., Do, Q. B. P., Furbish, K., Burke, T. A., Martinez, A. P., & Gerlus, N.
- Affiliations
- Harvard University (US)
- Williams College (US)
- University of Pittsburgh (US)
- Boston University (US)
- Brown University (US)
- Duke University (US)
- Corresponding author
- Liu, Richard T.
- ORCID
- Venue
- Clinical Psychology Review
- Publisher
- Elsevier BV
- Published
- 2020-11
- Volume
- 81
- Pages
- 101895
- ISSN
- 0272-7358 (ISSN-L)
- PMC
- PMC7731893
- OpenAlex
- W3048003475
- Semantic Scholar
- e2061d58ba7d987818cbae9d256c9ca92ce8bd2a
- Cited by
- 239
- References
- 100
- Citations by year
- 2026: 49 · 2025: 53 · 2024: 49 · 2023: 40 · 2022: 25 · 2021: 20 · 2020: 3
- FWCI
- 1.74
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Clinical Psychology Review (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Smith ScholarWorks (Smith College) (submittedVersion)
- Funders
- National Institute of Mental Health
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Keywords
- sleep disorders, insomnia, suicidal ideation, suicide attempts, suicide risk, short-term risk, sleep dysregulation, neuroinflammation, stress, executive function, suicide warning signs
- MeSH terms
- Suicide, Completed, Adult, Aged, Female, Humans, Sleep Initiation and Maintenance Disorders, Longitudinal Studies, Male, Middle Aged, Risk Factors, Sleep Wake Disorders, Suicide, Attempted, Young Adult, Suicidal Ideation
About these checks
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