Cited by 107Malaria Research and ControlBlood groups and transfusionHemoglobinopathies and Related Disorders

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Plasmodium falciparum: Chondroitin sulfate A is the major receptor for adhesion of parasitized erythrocytes in the placenta

Fried, Michal, Domingo, Gonzalo J., Gowda, Channe D., Mutabingwa, Theonest K., Duffy, Patrick E.·2006·Experimental Parasitology

DOI 10.1016/j.exppara.2005.12.003

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Abstract

Plasmodium falciparum parasites that sequester in the placenta bind to the molecule chondroitin sulfate A (CSA). Women become resistant to malaria during pregnancy as they acquire antibodies that inhibit parasite adhesion to CSA, suggesting that a vaccine against placental malaria is feasible. Hyaluronic acid (HA) and non-immune IgG have also been proposed as receptors for P. falciparum adhesion in the placenta, but evidence for their roles is inconclusive. In this study, CSA, HA, and IgG were simultaneously assessed for their relative contributions to placental adhesion. Placental parasites collected in Tanzania uniformly adhered to the molecule CSA, and soluble CSA completely inhibited adhesion of most samples to placental cryosections. Three of 46 placental parasite samples also adhered to immobilized HA, but HA failed to inhibit adhesion of any placental parasites to placental cryosections. Similarly, non-immune IgG and protein A failed to inhibit adhesion of parasite samples to placental cryosection. P. falciparum adhesion in the placenta appears to be a non-redundant process that requires CSA as a receptor. Vaccines that elicit functional antibodies against CSA-binding parasites may confer resistance to pregnancy malaria.

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Miller, L. H., Mason, S. J., CLYDE, D. F., & McGinniss, M. H. (1976) · New England Journal of Medicine · doi:10.1056/nejm197608052950602 · Cited by 1,259
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Beeson, J. G., Rogerson, S. J., Cooke, B. M., Reeder, J. C., Chai, W., Lawson, A. M., Molyneux, M. E., & Brown, G. V. (2000) · Nature Medicine · doi:10.1038/71582 · Cited by 310
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Beeson, J. G., Brown, G. V., Molyneux, M. E., Mhango, C., Dzinjalamala, F., & Rogerson, S. J. (1999) · The Journal of Infectious Diseases · doi:10.1086/314899 · Cited by 266
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Ockenhouse, C., Ho, M., Tandon, N., van Seventer, G. A., Shaw, S., White, N. J., Jamieson, G., Chulay, J. D., & Webster, H. K. (1991) · The Journal of Infectious Diseases · doi:10.1093/infdis/164.1.163 · Cited by 215
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Ismail, K. A., Abdelwahab, M. M., Rezk, H. M., & Khalifa, A. M. (2016) · Infectious Diseases in Clinical Practice · doi:10.1097/ipc.0000000000000412
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Mitran, C. J. (2021) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3-qs9p-em57
Conclusion
Leuridan, E. E., Nunes, M. C., & Jones, C. E. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-814582-1.00016-4
Faculty Opinions recommendation of HIV impairs opsonic phagocytic clearance of pregnancy-associated malaria parasites.
Duffy, P. A. (2007) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.1088087.541071
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Disease Models in Malarial Research
Banerjee, P., & Sanyal, S. (2023) · Springer eBooks · doi:10.1007/978-3-031-20521-7_8
Additional file 2 of Plasmodium falciparum alters the trophoblastic barrier and stroma villi organization of human placental villi explants
López-Guzmán, C., García, A. M., Ramirez, J. D., Aliaga, T. T., Fernández-Moya, A., Kemmerling, U., & Vásquez, A. M. (2024) · Figshare · doi:10.6084/m9.figshare.25734694

Authors: Fried, M., Domingo, G. J., Gowda, C. D., Mutabingwa, T. K., & Duffy, P. E.
Affiliations: Center for Infectious Disease Research (US)
Pennsylvania State University (US)
Corresponding author: Fried, Michal
ORCID: Fried, Michal
Domingo, Gonzalo J.
Duffy, Patrick E.
Venue: Experimental Parasitology
Publisher: Elsevier BV
Published: 2006-05
Volume: 113
Issue: 1
Pages: 36-42
ISSN: 0014-4894 (ISSN-L)
DOI: 10.1016/j.exppara.2005.12.003
OpenAlex: W2084381085
Cited by: 107
References: 27
Citations by year: 2026: 4 · 2025: 2 · 2024: 5 · 2023: 2 · 2022: 2 · 2021: 4 · 2020: 5 · 2019: 5 · 2018: 1 · 2017: 8 · 2016: 4 · 2015: 1 · 2014: 2 · 2013: 3 · 2012: 7
FWCI: 15.31
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Experimental Parasitology (publishedVersion)
PubMed (publishedVersion)
Funders: Bill and Melinda Gates Foundation
National Institutes of Health
National Institute of Allergy and Infectious Diseases (AI52059, R01AI052059)
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
Health Sciences › Medicine › Hematology › Blood groups and transfusion
Health Sciences › Medicine › Genetics (clinical) › Hemoglobinopathies and Related Disorders
Keywords: Plasmodium falciparum, chondroitin sulfate A, placental malaria, parasite adhesion, receptor specificity, hyaluronic acid, placental sequestration
MeSH terms: Adolescent, Adult, Animals, Cell Adhesion, Chondroitin Sulfates, Erythrocytes, Female, Humans, Hyaluronic Acid, Immunoglobulin G, Middle Aged, Placenta, Plasmodium falciparum, Pregnancy, Tanzania, Malaria Vaccines

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Plasmodium falciparum: Chondroitin sulfate A is the major receptor for adhesion of parasitized erythrocytes in the placenta

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