The DOI matches its Crossref record; 95 of the 95 references it cites were found in a registry or an index.
Calorie restriction and prevention of age‐associated chronic disease
Open accessAbstract
Life expectancy in the world has increased dramatically during the last century; the number of older adults is expected to rise while the number of youths will decline in the near future. This demographic shift has considerable public health and economic implications since aging is associated with the development of serious chronic diseases. Calorie restriction (CR) is the most effective nutritional intervention for slowing aging and preventing chronic disease in rodents. In non‐human and human primates, CR with adequate nutrition protects against abdominal obesity, diabetes, hypertension and cardiovascular diseases. Cancer morbidity and mortality are also diminished in CR monkeys, and data obtained from individuals practicing long‐term CR show a reduction of metabolic and hormonal factors associated with increased cancer risk.
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“Calorie restriction is another widely known lifestyle intervention that can prevent age-related metabolic disorders in multiple species217.”
From Mitochondrial and metabolic dysfunction in ageing and age-related diseases (2022) · cites this paper as [217]
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Mitochondrial and metabolic dysfunction in ageing and age-related diseases
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Metadata
- Authors
- Omodei, D., & Fontana, L.
- Affiliations
- Washington University in St. Louis (US)
- Corresponding author
- Fontana, Luigi
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2011-03-12
- Volume
- 585
- Issue
- 11
- Pages
- 1537-1542
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- PMC
- PMC3439843
- OpenAlex
- W2054879507
- Cited by
- 293
- References
- 95
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 12 · 2023: 19 · 2022: 13 · 2021: 14 · 2020: 39 · 2019: 17 · 2018: 20 · 2017: 21 · 2016: 20 · 2015: 19 · 2014: 21 · 2013: 36 · 2012: 21
- FWCI
- 2.78
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- FEBS Letters (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Institutional Research Information System (Università degli Studi di Brescia) (submittedVersion)
- Funders
- National Center for Research Resources (UL1 RR024992)
- National Institute of Diabetes and Digestive and Kidney Diseases (P30DK056341)
- Istituto Superiore di Sanità/National Institutes of Health Collaboration Program, Ministero della Salute
- Longer Life Foundation
- Bakewell Foundation
- Scott and Annie Appleby Charitable Trust
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Aging › Genetics, Aging, and Longevity in Model Organisms
- Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
- Health Sciences › Medicine › Geriatrics and Gerontology › Sirtuins and Resveratrol in Medicine
- Keywords
- caloric restriction, aging, disease prevention, dietary intervention, obesity, diabetes mellitus, hypertension, cardiovascular disease, cancer risk, metabolic factors, hormonal factors, non-human primates, rodents
- MeSH terms
- Aging, Animals, Cardiovascular Diseases, Chronic Disease, Humans, Neoplasms, Caloric Restriction
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