Clinical studies show no effects of soy protein or isoflavones on reproductive hormones in men: Results of a meta-analysis

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How should meta‐regression analyses be undertaken and interpreted?

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The clinical importance of the metabolite equol-a clue to the effectiveness of soy and its isoflavones

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INTENSIVE LIFESTYLE CHANGES MAY AFFECT THE PROGRESSION OF PROSTATE CANCER

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Testosterone action on skeletal muscle

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Estimated Asian adult soy protein and isoflavone intakes

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Soy Isoflavones and Cancer Prevention

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Estrogen Receptor β-Selective Transcriptional Activity and Recruitment of Coregulators by Phytoestrogens

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Effects of the Phytoestrogen Genistein on Bone Metabolism in Osteopenic Postmenopausal Women

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Hormonal Predictors of Prostate Cancer: A Meta-Analysis

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Chapter 2: The Role of Steroid Hormones in Prostate Carcinogenesis

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Phytoestrogens Modulate Binding Response of Estrogen Receptors α and β to the Estrogen Response Element

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Factors Affecting the Bioavailability of Soy Isoflavones in Humans after Ingestion of Physiologically Relevant Levels from Different Soy Foods

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Short-term Effects of Phytoestrogen-rich Diet on Postmenopausal Women

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Dietary soy-phytoestrogens decrease testosterone levels and prostate weight without altering LH, prostate 5alpha-reductase or testicular steroidogenic acute regulatory peptide levels in adult male Sprague-Dawley rats

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Reproductive effects in male and female rats of neonatal exposure to genistein

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Effect of a phytoestrogen food supplement on reproductive health in normal males

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Genistein as an Inducer of Tumor Cell Differentiation: Possible Mechanisms of Action

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Isoflavone treatment for acute menopausal symptoms

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Effects of a diet rich in phytoestrogens on prostate-specific antigen and sex hormones in men diagnosed with prostate cancer

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Soy Isoflavones in the Treatment of Prostate Cancer

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The specific role of isoflavones in reducing prostate cancer risk

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Influence of 10 wk of soy consumption on plasma concentrations and excretion of isoflavonoids and on gut microflora metabolism in healthy adults

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An Overview of the Health Effects of Isoflavones with an Emphasis on Prostate Cancer Risk and Prostate-Specific Antigen Levels

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Soy isoflavone genistein in prevention and treatment of prostate cancer

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Randomized, Double-Blind, Placebo-Controlled Crossover Study in Men with Prostate Cancer and Rising PSA: Effectiveness of a Dietary Supplement

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Effects of a genistein-rich extract on PSA levels in men with a history of prostate cancer

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Induction of apoptosis in low to moderate-grade human prostate carcinoma by red clover-derived dietary isoflavones.

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Genistein exerts estrogen-like effects in male mouse reproductive tract

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Phase II trial of isoflavone in prostate-specific antigen recurrent prostate cancer after previous local therapy

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Andropause: is androgen replacement therapy indicated for the aging male?

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Isoflavone supplements containing predominantly genistein reduce hot flash symptoms

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Clinical Characteristics and Pharmacokinetics of Purified Soy Isoflavones: Multiple-Dose Administration to Men with Prostate Neoplasia

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Effects of the phytoestrogen genistein on hot flushes, endometrium, and vaginal epithelium in postmenopausal women

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A Combination of Tomato and Soy Products for Men With Recurring Prostate Cancer and Rising Prostate Specific Antigen

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Ligands Differentially Modulate the Protein Interactions of the Human Estrogen Receptors α and β

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Effects of Chronic Dietary Exposure to Genistein, a Phytoestrogen, During Various Stages of Development on Reproductive Hormones and Spermatogenesis in Rats

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The differential ability of the phytoestrogen genistein and of estradiol to induce uterine weight and proliferation in the rat is associated with a substance specific modulation of uterine gene expression

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Isoflavone-Rich Soy Protein Isolate Suppresses Androgen Receptor Expression without Altering Estrogen Receptor-β Expression or Serum Hormonal Profiles in Men at High Risk of Prostate Cancer

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Effect of soymilk consumption on serum estrogen and androgen concentrations in Japanese men.

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Effects of replacing meat with soyabean in the diet on sex hormone concentrations in healthy adult males

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Free testosterone plasma levels are negatively associated with the intima-media thickness of the common carotid artery in overweight and obese glucose-tolerant young adult men

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A Phase II Randomized, Placebo-Controlled Clinical Trial of Purified Isoflavones in Modulating Steroid Hormones in Men Diagnosed With Localized Prostate Cancer

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Effects of raloxifene, hormone therapy, and soy isoflavone on serum high-sensitive C-reactive protein in postmenopausal women

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Effect of protein source and resistance training on body composition and sex hormones

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Minimal effect of a low-fat/high soy diet for asymptomatic, hormonally naive prostate cancer patients.

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Soy protein isolates of varying isoflavone content exert minor effects on serum reproductive hormones in healthy young men

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The effects of soy protein in women and men with elevated plasma lipids

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Dietary supplements of soya flour lower serum testosterone concentrations and improve markers of oxidative stress in men

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The effect of the phytoestrogen genistein and hormone replacement therapy on homocysteine and C-reactive protein level in postmenopausal women

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Serum prostate-specific antigen but not testosterone levels decrease in a randomized soy intervention among men

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Dietary Soy Protein Isolate Modifies Hepatic Retinoic Acid Receptor-β Proteins and Inhibits Their DNA Binding Activity in Rats

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Clinical and Biological Activity of Soy Protein Powder Supplementation in Healthy Male Volunteers

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Effects of Soy Protein on Levels of Remnant-like Particles Cholesterol and Vitamin E in Healthy Men.

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Development of Rat Prostatitis Model by Oral Administration of Isoflavone and Its Characteristics

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Feasibility of a low-fat/high-fiber diet intervention with soy supplementation in prostate cancer patients after prostatectomy

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Estrogen receptor expression in the prostate of rats treated with dietary genistein

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The effect of isoflavone extract ingestion, as Trinovin, on plasma steroids in normal men

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The effects of short-term oral phytoestrogen supplementation on the hypothalamic-pituitary-testicular axis in prostate cancer patients

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Hormonal Response to Diets High in Soy or Animal Protein Without and With Isoflavones in Moderately Hypercholesterolemic Subjects

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Soy protein intake by active young adult men raises plasma antioxidant capacity without altering plasma testosterone

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Increased one week soybean consumption affects spatial abilities but not sex hormone status in men

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Plant Proteins: Assessing Their Nutritional Quality and Effects on Health and Physical Function

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Sustaining Protein Nutrition Through Plant-Based Foods

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Adverse Effects of Nutraceuticals and Dietary Supplements

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Soy, phytoestrogens and their impact on reproductive health

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Effects of Dietary Phytoestrogens on Hormones throughout a Human Lifespan: A Review

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Healthy Plant-Based Diets Are Associated with Lower Risk of All-Cause Mortality in US Adults

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Efficacy and Safety of Short-Term Genistein Intervention in Patients with Localized Prostate Cancer Prior to Radical Prostatectomy: A Randomized, Placebo-Controlled, Double-Blind Phase 2 Clinical Trial

Lazarevic, B., Boezelijn, G., Diep, L. M., Kvernrød, K., Øgren, O., Ramberg, H., Moen, A. R., Wessel, N., Berg, R. E., Egge-Jacobsen, W. M., et al. (2011) · Nutrition and Cancer · doi:10.1080/01635581.2011.582221 · Cited by 159 · see citing works

Soy and soy isoflavones in prostate cancer: a systematic review and meta‐analysis of randomized controlled trials

van Die, M. D., Bone, K. M., Williams, S., & Pirotta, M. V. (2013) · British Journal of Urology · doi:10.1111/bju.12435 · Cited by 130 · see citing works

The Role of Soy in Vegetarian Diets

Messina, M. J., & Messina, V. (2010) · Nutrients · doi:10.3390/nu2080855 · Cited by 133 · see citing works

Improvement of Testicular Steroidogenesis Using Flavonoids and Isoflavonoids for Prevention of Late-Onset Male Hypogonadism

Martin, L. J., & Touaibia, M. (2020) · Antioxidants · doi:10.3390/antiox9030237 · Cited by 120 · see citing works

The Influence of Metabolic Factors and Diet on Fertility

Łakoma, K., Kukharuk, O., & Śliż, D. (2023) · Nutrients · doi:10.3390/nu15051180 · Cited by 97 · see citing works

Soy and Isoflavone Consumption and Multiple Health Outcomes: Umbrella Review of Systematic Reviews and Meta‐Analyses of Observational Studies and Randomized Trials in Humans

Li, N., Wu, X., Zhuang, W., Xia, L., Chen, Y., Zhao, R., Yi, M., Wan, Q., Du, L., & Zhou, Y. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201900751 · Cited by 83 · see citing works

Soybean isoflavone exposure does not have feminizing effects on men: a critical examination of the clinical evidence

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Short-Term Soy Isoflavone Intervention in Patients with Localized Prostate Cancer: A Randomized, Double-Blind, Placebo-Controlled Trial

Hamilton‐Reeves, J. M., Banerjee, S., Banerjee, S. K., Holzbeierlein, J. M., Thrasher, J. B., Kambhampati, S., Keighley, J., & Veldhuizen, P. J. V. (2013) · PLoS ONE · doi:10.1371/journal.pone.0068331 · Cited by 76 · see citing works

Neither soyfoods nor isoflavones warrant classification as endocrine disruptors: a technical review of the observational and clinical data

Messina, M. J., Mejía, S. B., Cassidy, A., Duncan, A. M., Kurzer, M. S., Nagato, C., Ronis, M. J. J., Rowland, I. R., Sievenpiper, J. L., & Barnes, S. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1895054 · Cited by 75 · see citing works

Isoflavones derived from plant raw materials: bioavailability, anti-cancer, anti-aging potentials, and microbiome modulation

Aboushanab, S. A., Khedr, S. M., Гетте, И. Ф., Danilova, I. G., Кольберг, Н. А., Ravishankar, G. A., Rao, A. R., & Kovaleva, E. G. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1946006 · Cited by 75 · see citing works

Biochemical investigation and gene analysis of equol: A plant and soy‐derived isoflavonoid with antiaging and antioxidant properties with potential human skin applications

Gopaul, R., Knaggs, H. E., & Lephart, E. D. (2012) · BioFactors · doi:10.1002/biof.191 · Cited by 72 · see citing works

Health impact of childhood and adolescent soy consumption

Messina, M. J., Rogero, M. M., Fisberg, M., & Waitzberg, D. L. (2017) · Nutrition Reviews · doi:10.1093/nutrit/nux016 · Cited by 73 · see citing works

Effects of soy containing diet and isoflavones on cytochrome P450 enzyme expression and activity

Ronis, M. J. J. (2016) · Drug Metabolism Reviews · doi:10.1080/03602532.2016.1206562 · Cited by 68 · see citing works

Neither soy nor isoflavone intake affects male reproductive hormones: An expanded and updated meta-analysis of clinical studies

Reed, K. E., Camargo, J. T., Hamilton‐Reeves, J. M., Kurzer, M. S., & Messina, M. J. (2020) · Reproductive Toxicology · doi:10.1016/j.reprotox.2020.12.019 · Cited by 71 · see citing works

Protein Supplementation Has Minimal Effects on Muscle Adaptations during Resistance Exercise Training in Young Men: A Double-Blind Randomized Clinical Trial

Reidy, P. T., Borack, M. S., Markofski, M. M., Dickinson, J. M., Deer, R. R., Husaini, S. H., Walker, D. K., Igbinigie, S., Robertson, S. M., Cope, M. B., et al. (2016) · The Journal of Nutrition · doi:10.3945/jn.116.231803 · Cited by 67 · see citing works

Dietary Soy Intake Is Not Associated with Risk of Cardiovascular Disease Mortality in Singapore Chinese Adults

Talaei, M., Koh, W., van Dam, R. M., Yuan, J., & Pan, A. (2014) · Journal of Nutrition · doi:10.3945/jn.114.190454 · Cited by 58 · see citing works

Effect of Soy in Men With Type 2 Diabetes Mellitus and Subclinical Hypogonadism – A Randomized Controlled Study

Sathyapalan, T., Rigby, A. S., Bhasin, S., Thatcher, N. J., Kilpatrick, E. S., & Atkin, S. L. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-2875 · Cited by 56 · see citing works

Does equol production determine soy endocrine effects?

Shor, D., Sathyapalan, T., Atkin, S. L., & Thatcher, N. J. (2012) · European Journal of Nutrition · doi:10.1007/s00394-012-0331-7 · Cited by 56 · see citing works

The Potential Toxic Side Effects of Flavonoids

Tang, Z., & Zhang, Q. (2021) · Biocell · doi:10.32604/biocell.2022.015958 · Cited by 54 · see citing works

Systematic review and meta-analysis of soy products consumption in patients with type 2 diabetes mellitus.

Yang, B., Chen, Y., Xu, T., Yu, Y., Huang, T., Hu, X., & Li, D. (2011) · PubMed · Cited by 54 · see citing works

Isoflavones and Prostate Cancer

Zhang, H., Cui, J., Zhang, Y., Wang, Z., Chong, T., & Wang, Z. (2016) · Chinese Medical Journal · doi:10.4103/0366-6999.174488 · Cited by 54 · see citing works

Phytoestrogens (Resveratrol and Equol) for Estrogen-Deficient Skin—Controversies/Misinformation versus Anti-Aging In Vitro and Clinical Evidence via Nutraceutical-Cosmetics

Lephart, E. D. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222011218 · Cited by 55 · see citing works

Soy Isoflavones Genistein and Daidzein Exert Anti-Apoptotic Actions via a Selective ER-mediated Mechanism in Neurons following HIV-1 Tat1–86 Exposure

Adams, S. M., Aksenova, M. V., Aksenov, M. Y., Mactutus, C. F., & Booze, R. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037540 · Cited by 52 · see citing works

Development of genomic resources for the narrow-leafed lupin (Lupinus angustifolius): construction of a bacterial artificial chromosome (BAC) library and BAC-end sequencing

Gao, L., Hane, J. K., Kamphuis, L. G., Foley, R. C., Shi, B.-J., Atkins, C. A., & Singh, K. B. (2011) · BMC Genomics · doi:10.1186/1471-2164-12-521 · Cited by 52 · see citing works

The essential role of genetic resources in narrow-leafed lupin improvement

Berger, J. D., Clements, J. C., Nelson, M. N., Kamphuis, L. G., Singh, K. B., & Buirchell, B. J. (2013) · Australian Journal of Agricultural Research · doi:10.1071/cp13092 · Cited by 50 · see citing works

Androgen receptor and soy isoflavones in prostate cancer (Review)

Sivoňov�, M., Kapl�n, P., Tatarkov�, Z., Lichardusov�, L., Dusenka, R., & Jurečekov�, J. (2018) · Molecular and Clinical Oncology · doi:10.3892/mco.2018.1792 · Cited by 47 · see citing works

Soy Bioactive Components in Functional Perspective: A Review

Garg, S., Lule, V. K., Malik, R. K., & Tomar, S. K. (2016) · International Journal of Food Properties · doi:10.1080/10942912.2015.1136936 · Cited by 48 · see citing works

The Role of Nutraceuticals in Male Fertility

Ko, E., & Sabanegh, E. S. (2013) · Urologic Clinics of North America · doi:10.1016/j.ucl.2013.08.003 · Cited by 41 · see citing works

Dietary Soy Intake Is Inversely Associated with Risk of Type 2 Diabetes in Japanese Women but Not in Men

Konishi, K., Wada, K., Yamakawa, M., Goto, Y., Mizuta, F., Koda, S., Uji, T., Tsuji, M., & Nagata, C. (2019) · Journal of Nutrition · doi:10.1093/jn/nxz047 · Cited by 35 · see citing works

The role of soy and soy isoflavones on women’s fertility and related outcomes: An update

Rizzo, G., Feraco, A., Storz, M. A., & Lombardo, M. (2022) · Journal of Nutritional Science · doi:10.1017/jns.2022.15 · Cited by 34 · see citing works

The Soy Isoflavone Genistein Blunts Nuclear Factor Kappa-B, MAPKs and TNF-α Activation and Ameliorates Muscle Function and Morphology in Mdx Mice

Messina, S., Bitto, A., Aguennouz, M., Vita, G. L., Polito, F., Irrera, N., Altavilla, D., Marini, H., Migliorato, A., Squadrito, F., et al. (2011) · Neuromuscular Disorders · doi:10.1016/j.nmd.2011.04.014 · Cited by 33 · see citing works

How Food Choices Impact on Male Fertility

Pecora, G., Sciarra, F., Gangitano, E., & Venneri, M. A. (2023) · Current Nutrition Reports · doi:10.1007/s13668-023-00503-x · Cited by 33 · see citing works

Phytoestrogens in Human Pregnancy

Jarrell, J. F., Foster, W. G., & Kinniburgh, D. W. (2012) · Obstetrics and Gynecology International · doi:10.1155/2012/850313 · Cited by 33 · see citing works

The relationship between diet, energy balance and fertility in men

Suliga, E., & Głuszek, S. (2019) · International Journal for Vitamin and Nutrition Research · doi:10.1024/0300-9831/a000577 · Cited by 32 · see citing works

Sex-specific associations of habitual intake of soy protein and isoflavones with risk of type 2 diabetes

Woo, H. W., Kim, M. K., Lee, Y. H., Shin, D. H., Shin, M., & Choi, B. Y. (2020) · Clinical Nutrition · doi:10.1016/j.clnu.2020.04.035 · Cited by 32 · see citing works

Phenolics in Human Nutrition: Importance of the Intestinal Microbiome for Isoflavone and Lignan Bioavailability

Clavel, T., & Mapesa, J. O. (2013) · Springer eBooks · doi:10.1007/978-3-642-22144-6_94 · Cited by 31 · see citing works

Role of soybean-derived bioactive compounds in inflammatory bowel disease

Juritsch, A. F., & Moreau, R. F. (2018) · Nutrition Reviews · doi:10.1093/nutrit/nuy021 · Cited by 31 · see citing works

Flavonoids and Related Members of the Aromatic Polyketide Group in Human Health and Disease: Do They Really Work?

Tauchen, J., Huml, L., Rimpelová, S., & Jurášek, M. (2020) · Molecules · doi:10.3390/molecules25173846 · Cited by 30 · see citing works

Human-relevant potency threshold (HRPT) for ERα agonism

Borgert, C. J., Matthews, J. C., & Baker, S. P. (2018) · Archives of Toxicology · doi:10.1007/s00204-018-2186-z · Cited by 26 · see citing works

Application of the BRAFO-tiered approach for benefit-risk assessment to case studies on natural foods

Watzl, B., Gelencsér, É., Hoekstra, J., Kulling, S. E., Lydeking-Olsen, E., Rowland, I. R., Schilter, B., van Klaveren, J., & Chiodini, A. M. (2011) · Food and Chemical Toxicology · doi:10.1016/j.fct.2011.02.010 · Cited by 25 · see citing works

Manipulation of Dietary Intake on Changes in Circulating Testosterone Concentrations

Zamir, A., Ben‐Zeev, T., & Hoffman, J. R. (2021) · Nutrients · doi:10.3390/nu13103375 · Cited by 23 · see citing works

Review: Anti-Oxidant and Anti-Aging Properties of Equol in Prostate Health (BPH)

Lephart, E. D. (2014) · Open Journal of Endocrine and Metabolic Diseases · doi:10.4236/ojemd.2014.41001 · Cited by 22 · see citing works

Impact of soy consumption on human health: integrative review

Nogueira‐de‐Almeida, C. A., Ferraz, I. S., Ued, F. D. V., Almeida, A. C. F., & Ciampo, L. A. D. (2020) · Brazilian journal of food technology/Brazilian Journal of Food Technology · doi:10.1590/1981-6723.12919 · Cited by 23 · see citing works

Principles of herbal pharmacology

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Soy isoflavone consumption and age at pubarche in adolescent males

Segovia‐Siapco, G., Pribis, P., Oda, K., & Sabaté, J. (2017) · European Journal of Nutrition · doi:10.1007/s00394-017-1504-1 · Cited by 21 · see citing works

Phytoestrogen biomonitoring: an extractionless LC-MS/MS method for measuring urinary isoflavones and lignans by use of atmospheric pressure photoionization (APPI)

Parker, D. L., Rybak, M. E., & Pfeiffer, C. M. (2011) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-011-5550-x · Cited by 20 · see citing works

The Effect of Soy Isoflavones on Steroid Metabolism

Swart, A. C., Johannes, I. D., Sathyapalan, T., & Atkin, S. L. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00229 · Cited by 18 · see citing works

Effective Anti-aging Strategies in an Era of Super-aging

Park, S., Yang, M.-J., Ha, S.-N., & Lee, J. (2014) · Journal of Menopausal Medicine · doi:10.6118/jmm.2014.20.3.85 · Cited by 18 · see citing works

The chronic alcohol consumption influences the gonadal axis in men: Results from a meta‐analysis

Santi, D., Cignarelli, A., Baldi, M., Sansone, A., Spaggiari, G., Simoni, M., & Corona, G. (2024) · Andrology · doi:10.1111/andr.13526 · Cited by 17 · see citing works

Prevention of Male Late-Onset Hypogonadism by Natural Polyphenolic Antioxidants

Martin, L. J., & Touaibia, M. (2024) · Nutrients · doi:10.3390/nu16121815 · Cited by 16 · see citing works

Regulation of the neuroendocrine axis in male rats by soy-based diets is independent of age and due specifically to isoflavone action†

Jeminiwa, B. O., Knight, R. M., Braden, T. D., Cruz‐Espindola, C., Boothe, D. M., & Akingbemi, B. T. (2020) · Biology of Reproduction · doi:10.1093/biolre/ioaa101 · Cited by 17 · see citing works

Phytoestrogens as Pharma Foods

Gupta, C., Prakash, D., & Gupta, S. L. (2016) · Advanced in Food Technology and Nutritional Sciences - Open Journal · doi:10.17140/aftnsoj-2-127 · Cited by 16 · see citing works

The effects of tamoxifen and soy on dark neuron production in hippocampal formation after pentylenetetrazole-induced repeated seizures in rats

Ebrahimzadeh‐Bideskan, A., Ataei, M. L., Mansouri, S., & Hosseini, M. (2015) · Pathophysiology · doi:10.1016/j.pathophys.2015.04.001 · Cited by 15 · see citing works

Secondary Hypogonadism due to Excessive Ingestion of Isoflavone in a Man

Imai, H., Nishikawa, H., Suzuki, A., Kodama, E., Iida, T., Mikura, K., Hashizume, M., Kigawa, Y., Tadokoro, R., Sugisawa, C., et al. (2022) · Internal Medicine · doi:10.2169/internalmedicine.8578-21 · Cited by 15 · see citing works

The relationship between plant and animal based protein with semen parameters: A cross-sectional study in infertile men

Abdollahi, N., Nouri, M., Leilami, K., Mustafa, Y. F., & Shirani, M. (2022) · Clinical Nutrition ESPEN · doi:10.1016/j.clnesp.2022.03.019 · Cited by 13 · see citing works

Sociodemographic and Lifestyle Variables Are Compound- and Class-Specific Correlates of Urine Phytoestrogen Concentrations in the U.S. Population

Rybak, M. E., Sternberg, M., & Pfeiffer, C. M. (2013) · Journal of Nutrition · doi:10.3945/jn.112.172981 · Cited by 12 · see citing works

Impact of 18-Month Soy Protein Supplementation on Steroid Hormones and Serum Biomarkers of Angiogenesis, Apoptosis, and the Growth Hormone/IGF-1 Axis: Results of a Randomized, Placebo-Controlled Trial in Males Following Prostatectomy

Bosland, M. C., Huang, J. H., Schlicht, M. J., Enk, E., Xie, H. W., & Kato, I. (2021) · Nutrition and Cancer · doi:10.1080/01635581.2020.1870706 · Cited by 12 · see citing works

Exploring the Soyfood Controversy

Messina, M. J., & Messina, V. (2013) · Nutrition Today · doi:10.1097/nt.0b013e31828fff54 · Cited by 11 · see citing works

Does soy protein affect circulating levels of unbound IGF-1?

Messina, M. J., & Magee, P. J. (2017) · European Journal of Nutrition · doi:10.1007/s00394-017-1459-2 · Cited by 11 · see citing works

Gender Differences in Protein Consumption and Body Composition: The Influence of Socioeconomic Status on Dietary Choices

Lombardo, M. (2025) · Foods · doi:10.3390/foods14050887 · Cited by 11 · see citing works

How Food Intakes Modify Testosterone Level

Terrier, J., & Isidori, A. M. (2016) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2016.07.001 · Cited by 10 · see citing works

Determination of S- and/or R-equol in plant-based food products and efficacy of topical or oral 4′,7-isoflavandiol (R/S equol) to improve skin health in adult men, a Placebo-controlled pilot study

Lephart, E. D. (2021) · Journal of Functional Foods · doi:10.1016/j.jff.2021.104563 · Cited by 10 · see citing works

Combined effects of urinary phytoestrogens metabolites and polymorphisms in metabolic enzyme gene on idiopathic male infertility

Qin, Y., Du, G., Chen, M., Hu, W., Lu, C., Wu, W., Hang, B., Zhou, Z., Wang, X., & Xia, Y. (2014) · Archives of Toxicology · doi:10.1007/s00204-014-1205-y · Cited by 10 · see citing works

Isoflavones: toxicological aspects and efficacy

Esch, H. L., & Lehmann, L. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-821038-3.00045-8 · Cited by 9 · see citing works

Potential Intervention Targets in Utero and Early Life for Prevention of Hormone Related Cancers

Schooling, C. M., Houghton, L. C., & Terry, M. B. (2016) · PEDIATRICS · doi:10.1542/peds.2015-4268e · Cited by 9 · see citing works

Long time exposure to soy/isoflavone-rich diet enhances testicular and prostate health in Long-Evans rats

Blake, C., Hansen, T., Simmons, T. C., & Lephart, E. D. (2013) · Journal of Functional Foods · doi:10.1016/j.jff.2013.04.009 · Cited by 8 · see citing works

Soy Protein Isolate Suppresses Bone Resorption and Improves Trabecular Microarchitecture in Spontaneously Hyperphagic, Rapidly Growing Male OLETF Rats

Dirkes, R. K., Richard, M. W., Meers, G. M.-E., Butteiger, D. N., Krul, E. S., Thyfault, J. P., Rector, R. S., & Hinton, P. S. (2018) · Current Developments in Nutrition · doi:10.1093/cdn/nzy010 · Cited by 8 · see citing works

Les aliments au soja : consommation en France, qualités nutritionnelles et données scientifiques récentes sur la santé

Chevalier, D., Debeuf, C., Joubrel, G., Kocken, M., & Planchenault, N. (2016) · OCL · doi:10.1051/ocl/2016025 · Cited by 6 · see citing works

Environment-wide association study to comprehensively test and validate associations between nutrition and lifestyle factors and testosterone deficiency: NHANES 1988–1994 and 1999–2004

López, D. S., Wulaningsih, W., Tsilidis, K. K., Baillargeon, J., Williams, S., Urban, R. J., & Rohrmann, S. (2020) · HORMONES · doi:10.1007/s42000-020-00179-w · Cited by 7 · see citing works

Isoflavones

Esch, H. L., Kleider, C., Scheffler, A., & Lehmann, L. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802147-7.00034-6 · Cited by 6 · see citing works

Soy protein isolate feeding does not result in reproductive toxicity in the pre-pubertal rat testis

Ronis, M. J. J., Gómez-Acevedo, H., Shankar, K., Sharma, N., Blackburn, M. L., Singhal, R., Mercer, K. E., & Badger, T. M. (2018) · Experimental Biology and Medicine · doi:10.1177/1535370218771333 · Cited by 5 · see citing works

If we eat soy, do we keep the beneficial effects of the Mediterranean diet?

Aulisa, G., Binda, C., Padua, E., Pratesi, A., Bellia, A., Bellia, C., & Lombardo, M. (2020) · Nutrition & Food Science · doi:10.1108/nfs-10-2019-0322 · Cited by 5 · see citing works

Antioxidant Treatment and Prevention of Human Sperm DNA Fragmentation: Role in Health and Fertility

Abad, C., Frau, J. G., Hannaoui, N., & García-Peiró, A. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-800872-0.00035-4 · Cited by 5 · see citing works

Potential beneficial effects of oral administration of isoflavones in patients with chronic mountain sickness

Cui, J., GAO, L., Hai-jun, Y., Wang, F., Jiang, C., & Gao, Y. (2013) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2013.1388 · Cited by 4 · see citing works

The association between soy consumption and metabolic syndrome in Chinese adults: a cross-sectional study

Hidayat, K., Huang, Y., Qian, X., Chen, X., Yu, L., Zhou, H., & Qin, L. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1637413 · Cited by 4 · see citing works

Symposium on Plant Polyphenols: Nutrition, Health and Innovations, June 2009

Chang, A. S., Yeong, B.-Y., & Koh, W. (2010) · Nutrition Reviews · doi:10.1111/j.1753-4887.2010.00283.x · Cited by 3 · see citing works

Consumption of soy isoflavones during the prepubertal phase delays puberty and causes hypergonadotropic hypogonadism with disruption of hypothalamic-pituitary gonadotropins regulation in male rats

Oliveira, J. M., de Oliveira, I. M., Sleiman, H. K., Forno, G. O. D., Romano, M. A., & Romano, R. M. (2022) · Toxicology Letters · doi:10.1016/j.toxlet.2022.08.004 · Cited by 3 · see citing works

Urinary equol is associated with bioavailable testosterone but not total testosterone in women

Dong, H., Xiong, F., Zhong, Q.-W., Li, Y.-H., Liu, M., Ling, W., Tang, X., & Chen, Y. (2019) · Endocrine Journal · doi:10.1507/endocrj.ej19-0319 · Cited by 3 · see citing works

Evidence does not support the conclusion that soy is an endocrine disruptor

Messina, M. J. (2011) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem.2011.271 · Cited by 3 · see citing works

The Impact of Soy Products and Isoflavones on Male Reproductive Hormones: A Systematic Review and Dose–Response Meta‐Analysis of Randomized Controlled Trials

Rajaie, S. H., Mohseni‐Takalloo, S., Sadeghi, O., & Hashempur, M. H. (2025) · Food Frontiers · doi:10.1002/fft2.70090 · Cited by 2 · see citing works

Modification of milk protein concentrate and applicability in high-protein nutrition bars

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Sex-specific associations between dietary legume subtypes and type 2 diabetes in a prospective cohort study

Woo, H. W., Hong, S., Shin, M., Koh, S. B., Kim, H. C., Kim, Y., & Kim, M. K. (2024) · Epidemiology and Health · doi:10.4178/epih.e2024083 · Cited by 1 · see citing works

Associations of dietary patterns and lower urinary tract symptoms (LUTS) in Korean adults

Lim, J.-S., Hwang, W., Kim, J. K., Kim, M., Kwon, O., Han, S., Oh, B., & Kim, J. S. (2025) · Nutrition Research and Practice · doi:10.4162/nrp.2025.19.2.318 · Cited by 1 · see citing works

Nutritional Value of Grain Legumes in Relation for Global Food Security

Січкар, В. І. (2025) · Acta fytotechnica et zootechnica/Acta fytotechnica et zootechnica · doi:10.15414/afz.2025.28.01.40-51 · Cited by 1 · see citing works

Soybean Phytoestrogens – Friends or Foes?

Šošić‐Jurjević, B., Filipovi, B., & SEKULI, M. I. (2011) · InTech eBooks · doi:10.5772/19078 · Cited by 1 · see citing works

Queer, Toxic Soybeans and Estrogen Panic: Gendered Food Fearmongering

Vaughn, R. (2022) · Media+Environment · doi:10.1525/001c.37271 · Cited by 1 · see citing works

Impact of Soybean Phytoestrogen-Rich Extract on Hormonal Imbalance and Ovarian Function in Menopausal Rat Induced with 4-Vinylcyclohexene Diepoxide: A Neglected Naturaceutical

Olaniyan, S. O., Abiodun, E. M., Oyakhire, F. O., Olaniyan, O., Juliana, E., Uwumarongie, O. H., Ugege, C. O., Kelly, E. I., & Efenarhua, S. (2024) · Scholars Journal of Applied Medical Sciences · doi:10.36347/sjams.2024.v12i04.013 · Cited by 1 · see citing works

Prostate cancer chemoprevention in men of African descent: current state of the art and opportunities for future research

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Isoflavones

Frankenfeld, C. L. (2020) · doi:10.1002/9781119563754.ch6 · Cited by 1 · see citing works

Letters to the Editor

Messina, M. J., Melby, M. K., Kronenberg, F., Kurzer, M. S., & Taku, K. (2013) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e318284e64a · Cited by 1 · see citing works

Neither soy nor isoflavone intake affects male reproductive hormones: An expanded and updated meta-analysis of clinical studies

Reed, K. E., Camargo, J. T., Hamilton‐Reeves, J. M., Kurzer, M. S., & Messina, M. J. (2020) · Reproductive Toxicology · doi:10.1016/j.reprotox.2020.12.019 · Cited by 71 · see citing works

Soybean isoflavone exposure does not have feminizing effects on men: a critical examination of the clinical evidence

Messina, M. J. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.03.002 · Cited by 79 · see citing works

The Impact of Soy Products and Isoflavones on Male Reproductive Hormones: A Systematic Review and Dose–Response Meta‐Analysis of Randomized Controlled Trials

Rajaie, S. H., Mohseni‐Takalloo, S., Sadeghi, O., & Hashempur, M. H. (2025) · Food Frontiers · doi:10.1002/fft2.70090 · Cited by 2 · see citing works

Re: Clinical Studies Show No Effects of Soy Protein or Isoflavones on Reproductive Hormones in Men: Results of a Meta-Analysis

Niederberger, C. (2011) · The Journal of Urology · doi:10.1016/s0022-5347(11)60138-9 · Cited by 2 · see citing works

Effect of soy isoflavone consumption on serum reproductive hormones in healthy young men

Dillingham, B. L. (2004) · The Atrium (University of Guelph)