Cited by 120Endometriosis Research and TreatmentPreterm Birth and ChorioamnionitisReproductive System and Pregnancy

Inflammation: A link between endometriosis and preterm birth

Open access
Petraglia, Felice, Arcuri, Felice, de Ziegler, Dominique, Chapron, Charles·2012·Fertility and Sterility

Abstract

Endometriosis is a chronic inflammatory disease affecting women's health. Pain and infertility are the major symptoms caused by a hormonal/immunological dysfunction, which causes an endometrial impairment. The same pathogenetic mechanisms are also associated with preterm birth: hormones, cytokines, neurohormones, and growth factors interact in modulating extracellular matrix and prostaglandin secretion, thus activating the inflammatory process in placental membranes and myometrium. An overlap of molecules and mechanisms may explain the evidence that preterm birth is a common outcome in pregnant patients with endometriosis.

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Crossref · 10.1016/j.fertnstert.2012.04.051

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Authors
Petraglia, F., Arcuri, F., de Ziegler, D., & Chapron, C.
Affiliations
  • University of Siena (IT)
  • Sorbonne Paris Cité (FR)
Corresponding author
Petraglia, Felice
Venue
Fertility and Sterility
Publisher
Elsevier BV
Published
2012-07
Volume
98
Issue
1
Pages
36-40
ISSN
0015-0282 (ISSN-L)
OpenAlex
W2054323092
Cited by
120
References
55
Citations by year
2026: 3 · 2025: 10 · 2024: 7 · 2023: 10 · 2022: 10 · 2021: 17 · 2020: 13 · 2019: 7 · 2018: 6 · 2017: 11 · 2016: 8 · 2015: 7 · 2014: 7 · 2013: 3 · 2012: 1
FWCI
0.79
Type
journal article
Language
en
Open access
Locations
  • Fertility and Sterility (publishedVersion)
  • PubMed (publishedVersion)
  • Florence Research (University of Florence) (submittedVersion)
  • Use Siena air (University of Siena) (submittedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
  • Health Sciences › Medicine › Epidemiology › Preterm Birth and Chorioamnionitis
  • Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
Keywords
endometriosis, preterm birth, inflammation, cytokines, neurohormones, growth factors, prostaglandins, extracellular matrix, placental membranes, myometrium, infertility, pregnancy outcomes
MeSH terms
Endometriosis, Female, Humans, Infant, Newborn, Inflammation, Pregnancy, Pregnancy Complications, Risk Factors, Uterine Diseases, Premature Birth

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