Anti-oxidative effect of mangiferin-chitosan nanoparticles on oxidative stress-induced renal cells
Abstract
Oxidative stress is considered to be the leading cause of many chronic and degenerative diseases leading to death and disability. Antioxidant therapy could be efficient in preventing oxidative stress-induced damages in cells. In the present study the efficacy of mangiferin-chitosan nanoparticles (MCNs) as a therapeutic agent against the oxidative stress, since mangiferin (MGF), a polyphenol protects and attenuates oxidative stress against various diseases. However, the bioactivity of MGF does not result in vivo biological effect owing to its low bioavailability and poor solubility. Mangiferin nanoparticles (NPs) were developed to improve the solubility and bioavailability of mangiferin. Nanoparticles had significant free radical scavenging activity in the cell-free system and had a synergistic action with phase II antioxidant enzymes such as catalases and peroxidases. A nephropathic system was developed to investigate the attenuative role of mangiferin-chitosan nanoparticles against induced oxidative stress, on normal kidney epithelial (NKE) cells. Pre-treatment with the nanoparticles exclusively prevented the induction of cytotoxicity induced by NaF and maintained the level of intracellular antioxidant enzyme in the cells. Nanoparticles had significant lipid peroxidation and protein oxidation inhibition activities. These nanoparticles can be used in food and pharmaceutical industries as a therapeutic agent to prevent the oxidative stress-induced health disorders.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Multiple delivery approaches (nanostructured lipid carriers, polymeric and chitosan-based nanogels, phospholipid complexes, targeted nanoparticles) have improved MGF exposure in preclinical systems.
“Multiple approaches have improved exposure in preclinical systems, including nanostructured lipid carriers, polymeric and chitosan-based nanogels, phospholipid complexes (2,172,173), and targeted nanoparticles designed to enhance intestinal uptake or lymphatic transport and to stabilize MGF against rapid metabolism (172,174-176).”
From Mangiferin in human disease: Multifaceted mechanisms and applications (Review) (2026) · cites this paper as [173]
Cites
Free radicals, antioxidants and functional foods: impact on human health
Lobo, V, Patil, A., Phatak, A., & Chandra, N. (2010) · Pharmacognosy Reviews · doi:10.4103/0973-7847.70902 · Cited by 5,435 · see citing works
Weydert, C. J. D., & Cullen, J. J. (2009) · Nature Protocols · doi:10.1038/nprot.2009.197 · Cited by 1,533 · see citing works
Detection of Necrosis by Release of Lactate Dehydrogenase Activity
Chan, F. K.-M., Moriwaki, K., & Rosa, M. J. D. (2013) · Methods in molecular biology · doi:10.1007/978-1-62703-290-2_7 · Cited by 791 · see citing works
ZITKA, O., SKALICKOVA, S., GUMULEC, J., MASARIK, M., ADAM, V., HUBALEK, J., TRNKOVA, L., KRUSEOVA, J., ECKSCHLAGER, T., & KIZEK, R. (2012) · Oncology Letters · doi:10.3892/ol.2012.931 · Cited by 664 · see citing works
Mangolim, C. S., Moriwaki, C., Nogueira, A. C., Sato, F., Baesso, M. L., Neto, A. M., & Matioli, G. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2013.12.067 · Cited by 528 · see citing works
Estimation of Scavenging Activity of Phenolic Compounds Using the ABTS•+ Assay
Nenadis, N., Wang, L., Tsimidou, M. Z., & Zhang, H. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0400056 · Cited by 496 · see citing works
Direct evidence for catalase and peroxidase activities of ferritin–platinum nanoparticles
Fan, J., Yin, J., Ning, B., Wu, X., Hu, Y., Mauro Ferrari, B., Anderson, G. J., Wei, J., Zhao, Y., & Nie, G. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.11.004 · Cited by 490 · see citing works
Mangiferin: A natural miracle bioactive compound against lifestyle related disorders
Imran, M., Arshad, M. S., Butt, M. S., Kwon, J.-H., Arshad, M. U., & Sultan, M. T. (2017) · Lipids in Health and Disease · doi:10.1186/s12944-017-0449-y · Cited by 366 · see citing works
Dar, A., Faizi, S., Naqvi, S., Roome, T., Zikr-ur-Rehman, S., Ali, M., Firdous, S., & Moin, S. T. (2005) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.28.596 · Cited by 289 · see citing works
Study to explore the mechanism to form inclusion complexes of β-cyclodextrin with vitamin molecules
Saha, S., Roy, A., Roy, K., & Roy, M. N. (2016) · Scientific Reports · doi:10.1038/srep35764 · Cited by 205 · see citing works
In vitro cytotoxicity MTT assay in Vero, HepG2 and MCF -7 cell lines study of Marine Yeast
Senthilraja, P., & Kathiresan, K. (2015) · Journal of Applied Pharmaceutical Science · doi:10.7324/japs.2015.50313 · Cited by 199 · see citing works
Antibacterial Effects of Chitosan/Cationic Peptide Nanoparticles
Tamara, F. R., Lin, C., Mi, F., & Ho, Y. (2018) · Nanomaterials · doi:10.3390/nano8020088 · Cited by 149 · see citing works
Das, J., Ghosh, J., Manna, P., & Sil, P. C. (2010) · Free Radical Research · doi:10.3109/10715760903513017 · Cited by 146 · see citing works
Antioxidant activity, total phenolic, and resveratrol content in five cultivars of peanut sprouts
Limmongkon, A., Janhom, P., Amthong, A., Kawpanuk, M., Nopprang, P., Poohadsuan, J., Somboon, T., Saijeen, S., Surangkul, D., Srikummool, M., et al. (2017) · Asian Pacific Journal of Tropical Biomedicine · doi:10.1016/j.apjtb.2017.01.002 · Cited by 104 · see citing works
Antioxidant activity of the mangiferin inclusion complex with β-cyclodextrin
Ferreira, F. D. R., Valentim, I. B., Ramones, E. L. C., Trevisan, M. T. S., Olea-Azar, C., Perez-Cruz, F., de Abreu, F. C., & Goulart, M. O. F. (2013) · LWT - Food Science and Technology · doi:10.1016/j.lwt.2012.09.032 · Cited by 73 · see citing works
Mangiferin alleviates arsenic induced oxidative lung injury via upregulation of the Nrf2-HO1 axis
Mahalanobish, S., Saha, S., Dutta, S., & Sil, P. C. (2019) · Food and Chemical Toxicology · doi:10.1016/j.fct.2019.02.022 · Cited by 60 · see citing works
Sun, J., He, X.-M., Zhao, M.-M., Li, L., Li, C., & Dong, Y. (2014) · Molecules · doi:10.3390/molecules190913147 · Cited by 59 · see citing works
Antioxidant Potential and Nutritional Values of Vegetables: A Review
Nahak, G., Suar, M., & Sahu, R. K. (2014) · Research Journal of Medicinal Plant · doi:10.3923/rjmp.2014.50.81 · Cited by 55 · see citing works
Biswas, S., Biswas, K., Richmond, A. L., Ko, J. S., Ghosh, S., Simmons, M. N., Rayman, P. A., Rini, B. I., Gill, I. S., Tannenbaum, C. S., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900259 · Cited by 53 · see citing works
Design and characterization of mangiferin nanoparticles for oral delivery
Samadarsi, R., & Dutta, D. (2018) · Journal of Food Engineering · doi:10.1016/j.jfoodeng.2018.11.020 · Cited by 52 · see citing works
Self-citationPhytochemical and Ethnomedicinal Uses of Family Violaceae
Chandra, D., Kohli, G., Prasad, K., Bisht, G., Punetha, V. D., Khetwal, K., Devrani, M. K., & Pandey, H. (2015) · Current Research in Chemistry · doi:10.3923/crc.2015.44.52 · Cited by 44 · see citing works
Peng, S., Hou, Y., Yao, J., & Fang, J. (2019) · BioFactors · doi:10.1002/biof.1488 · Cited by 37 · see citing works
Mangiferin protects osteoblast against oxidative damage by modulation of ERK5/Nrf2 signaling
Xia, G., Li, X., Zhu, X., Yin, X., Ding, H., & Qiao, Y. (2017) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2017.06.184 · Cited by 35 · see citing works
Joubert, E., Botha, M., Maicu, C., de Beer, D., & Manley, M. (2012) · South African Journal of Botany · doi:10.1016/j.sajb.2012.07.019 · Cited by 25 · see citing works
Mattioli, R., Mosca, L., Sánchez-Lamar, Á., Tempera, I., & Hausmann, R. (2018) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2018/3894381 · Cited by 20 · see citing works
Sadhukhan, P., Saha, S., & Sil, P. C. (2016) · Biomarkers · Cited by 13 · see citing works
Phytochemical and Ethnomedicinal Uses of Family Gentianaceae
Chandra, D., Kohli, G., Punetha, V. D., Prasad, K., Bisht, G., Khetwal, K., & Pandey, H. K. (2015) · Current Research in Chemistry · doi:10.3923/crc.2016.1.9 · Cited by 12 · see citing works
(2015) · Cited by 9 · see citing works
Self-citation
Flagged first, then by citations
1 of the 29 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Application of chitosan-based nanoparticles in skin wound healing
Loo, H. L., Goh, B. H., Lee, L., & Chuah, L. (2022) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2022.04.001 · Cited by 164 · see citing works
Deng, X., Lin, B., Wang, F., Xu, P., & Wang, N. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.155282 · Cited by 100 · see citing works
Mangiferin: a review of dietary sources, absorption, metabolism, bioavailability, and safety
Mei, S., Perumal, M., Battino, M., Kitts, D. D., Xiao, J., Ma, H., & Chen, X. (2023) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1983767 · Cited by 93 · see citing works
Wang, M., Huang, Z., Zhu, Y., He, P., & Fan, Q. (2023) · Food & Function · doi:10.1039/d3fo01157g · Cited by 73 · see citing works
El‐Saadony, M. T., Saad, A. M., Sitohy, M. Z., Alkafaas, S. S., Dladla, M., Ghosh, S. B., Mohammed, D. M., Soliman, T. N., Ibrahim, E. H., Fahmy, M. A., et al. (2025) · Materials Today Bio · doi:10.1016/j.mtbio.2025.102358 · Cited by 68 · see citing works
Application of nanotechnology in acute kidney injury: From diagnosis to therapeutic implications
Zhao, Y., Pu, M., Wang, Y., Yu, L., Song, X., & He, Z. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.06.026 · Cited by 62 · see citing works
Effectuality of chitosan biopolymer and its derivatives during antioxidant applications
Negm, N. A. M., Kana, M. T. H. A., Abubshait, S. A., & Betiha, M. A. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.07.197 · Cited by 57 · see citing works
The management of diabetes mellitus by mangiferin: advances and prospects
Wang, M., Liang, Y., Chen, K., Wang, M., Long, X., Liu, H., Sun, Y., & He, B. (2022) · Nanoscale · doi:10.1039/d1nr06690k · Cited by 56 · see citing works
Kang, L., Zhang, H., Jia, C.-Y., Zhang, R., & Shen, C. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.956355 · Cited by 55 · see citing works
The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view
Hassanein, E. H. M., Mohamed, W. R., Ahmed, O. S., Abdel‐Daim, M. M., & Sayed, A. M. M. (2022) · Life Sciences · doi:10.1016/j.lfs.2022.120971 · Cited by 47 · see citing works
Wang, M., Zhang, Z., Huo, Q., Wang, M., Sun, Y. Y., Liu, H., Chang, J., He, B., & Liang, Y. (2022) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.1c22964 · Cited by 45 · see citing works
Mangiferin: the miraculous xanthone with diverse pharmacological properties
Dutta, T., Das, T., Gopalakrishnan, A. V., Saha, S. C., Ghorai, M., Nandy, S., Kumar, M., Radha, Ghosh, A., Mukerjee, N., et al. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-022-02373-6 · Cited by 45 · see citing works
Therapeutic potential of mangiferin against kidney disorders and its mechanism of action: A review
Lum, P. T., Sekar, M., Gan, S. H., Jeyabalan, S., Bonam, S. R., Rani, N. N. I. M., Ku-Mahdzir, K.-M., Seow, L.-J., Wu, Y. S., Subramaniyan, V., et al. (2021) · Saudi Journal of Biological Sciences · doi:10.1016/j.sjbs.2021.11.016 · Cited by 40 · see citing works
Renoprotective Effects of Mangiferin: Pharmacological Advances and Future Perspectives
Akter, S., Moni, A., Faisal, G. M., Uddin, M. R., Jahan, N., Hannan, M. A., Rahman, A., & Uddin, M. J. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19031864 · Cited by 36 · see citing works
Design of Nanotechnological Carriers for Ocular Delivery of Mangiferin: Preformulation Study
Santonocito, D., Vivero-Lopez, M., Lauro, M. R., Torrisi, C., Castelli, F., Sarpietro, M. G., & Puglia, C. (2022) · Molecules · doi:10.3390/molecules27041328 · Cited by 32 · see citing works
Recent Formulation Advances of Mangiferin
Barakat, S., Nasr, M., Ahmed, R. F., Badawy, S., & Mortada, N. (2022) · Revista Brasileira de Farmacognosia · doi:10.1007/s43450-022-00297-z · Cited by 28 · see citing works
Tian, Y., Zhang, X., Du, M., Li, F., Xiao, M., & Zhang, W. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/9996040 · Cited by 28 · see citing works
de Queiroz, N. F., Steffani, J. A., Machado, L., Longhi, P., Montano, M. A. E., Martins, M., Machado, S. A., Machado, A. K., & Cadoná, F. C. (2021) · Journal of Toxicology and Environmental Health · doi:10.1080/15287394.2021.1945515 · Cited by 25 · see citing works
Demeyer, S., Athipornchai, A., Pabunrueang, P., & Trakulsujaritchok, T. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2021.117905 · Cited by 24 · see citing works
Mehany, H. M., El‐Shafai, N. M., Attia, A. M., Ibrahim, M. M., & El‐Mehasseb, I. M. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.06.171 · Cited by 23 · see citing works
Mangiferin: An effective agent against human malignancies
Irshad, N., Naeem, H., Shahbaz, M., Imran, M., Mujtaba, A., Hussain, M., Abdulmonem, W. A., Alsagaby, S. A., Yehuala, T. F., Abdelgawad, M. A., et al. (2024) · Food Science & Nutrition · doi:10.1002/fsn3.4434 · Cited by 14 · see citing works
Li, J., Duan, J., Hua, C., Pan, S., Li, G., Feng, Q., Liu, D., & Liu, Z. (2024) · Burns & Trauma · doi:10.1093/burnst/tkae044 · Cited by 15 · see citing works
Lopes, F. F. D. S., Lúcio, F. N. M., da Rocha, M. N., de Oliveira, V. M., Roberto, C. H. A., Marinho, M. M., Marinho, E. S., & de Morais, S. M. (2024) · 3 Biotech · doi:10.1007/s13205-024-03978-9 · Cited by 14 · see citing works
Ma, X., Allahou, L. W., Yang, R., Ma, Y., Dimoula, M., Chau, D. Y. S., Williams, G. R., Knowles, J. C., & Poma, A. (2025) · Materials Science and Engineering R Reports · doi:10.1016/j.mser.2025.101099 · Cited by 13 · see citing works
Potential of electro-sprayed purified mangiferin nanoparticles for anti-aging cosmetic applications
Chomchoei, N., Leelapornpisid, P., Tipduangta, P., Sangthong, P., Papan, P., Sirithunyalug, B., & Samutrtai, P. (2023) · RSC Advances · doi:10.1039/d3ra06308a · Cited by 12 · see citing works
Cao, W., Zhang, J., Yu, S., Gan, X., & An, R.-H. (2024) · Urolithiasis · doi:10.1007/s00240-023-01527-2 · Cited by 11 · see citing works
Lv, W., Chen, H., Zhou, P., Du, A., & Lei, Y. (2025) · International Journal of Rheumatic Diseases · doi:10.1111/1756-185x.70096 · Cited by 10 · see citing works
Abosharaf, H. A., Gebreel, D. T., Allam, S., El‐Atrash, A., & Tousson, E. (2024) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.13988 · Cited by 10 · see citing works
Multifunctional Nanosystem Based on Ultrasmall Carbon Dots for the Treatment of Acute Kidney Injury
Yao, H., Zhu, Z., Liu, M., Sun, F., Du, M., Sun, Y., & Du, B. (2024) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.4c00616 · Cited by 10 · see citing works
Environmental and toxicological implications of chitosan nanostructures
Khan, Z., Maqsood, Q., Baradokė, A., Ferreira, L. F. R., Franco, M., Schmidt, J. E., & Hussain, N. (2023) · Advances in chemical pollution, environmental management and protection · doi:10.1016/bs.apmp.2023.09.002 · Cited by 9 · see citing works
Alabrahim, O. A. A., Mohamad, K. A., Qaysson, B. T., Alwakeel, R., Chen, Y., Shui, M., Wang, S., & Farag, M. A. (2025) · RSC Advances · doi:10.1039/d5ra07267k · Cited by 12 · see citing works
Study of polysaccharide–gallic acid interaction and digestion behavior in biomimetic dietary fiber
Zhang, W., Zhang, Y., Zhang, Q., Ren, X., & Ge, J. (2025) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.14152 · Cited by 8 · see citing works
Melo-Betances, E., Rodríguez-Bautista, C. C., & Sellés, A. J. N. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1598719 · Cited by 8 · see citing works
Madbouly, N. A., Ooda, A., Nabil, A., Nasser, A., Ahmed, E., Ali, F., Mohamed, F., Faried, H., Badran, M., Ahmed, M., et al. (2024) · Inflammopharmacology · doi:10.1007/s10787-024-01464-5 · Cited by 8 · see citing works
Delgado, F. J. P., García-Villa, M. D., Fernández‐Quiroz, D., Villegas‐Ochoa, M. A., Domínguez-Avila, J. A., González-Aguilar, G. A., Ayala-Zavala, J. F., Martı́nez-Martı́nez, A., & Montiel‐Herrera, M. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.134343 · Cited by 8 · see citing works
Emerging Nanomedicine Strategies for Chronic Disease Management Based on Chitosan
Pacheco, Y. P., Parajuli, D., & Garcia‐Valls, R. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27031387 · Cited by 6 · see citing works
Goshtasbi, H., Abdolahinia, E. D., Fathi, M., Movafeghi, A., Omidian, H., Barar, J., & Omidi, Y. (2024) · Journal of Microencapsulation · doi:10.1080/02652048.2024.2319048 · Cited by 6 · see citing works
Vishwakarma, K. K., Hafeez, A., Usmani, S. A., Noor, L., & Khan, I. R. (2025) · Current Pharmaceutical Biotechnology · doi:10.2174/0113892010318524240907135527 · Cited by 4 · see citing works
Mangiferin in human disease: Multifaceted mechanisms and applications (Review)
Dai, Y., Huang, Q., Tan, M., Wang, Z., Jiang, C., Liu, Z., Zhang, S., & Song, S. (2026) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2026.5736 · Cited by 3 · see citing works
“…exposure in preclinical systems, including nanostruc‑ tured lipid carriers, polymeric and chitosan‑based nanogels, phospholipid complexes (2,172,173), and targeted nanoparticles designed to enhance intestinal uptake or lymphatic transport and to stabilize MGF against rapid metabolism…”
Emerging applications of nanotechnology in the treatment of acute kidney injury
Zeng, L., Kim, J., Choi, H. S., & Hutchens, M. P. (2025) · Nanomedicine · doi:10.1080/17435889.2025.2557747 · Cited by 3 · see citing works
A review on formulation and analytical aspect of mangiferin a natural phenolic xanthonoid
Shaikh, I., & Tatapudi, H. K. (2025) · Discover Chemistry · doi:10.1007/s44371-025-00193-0 · Cited by 3 · see citing works
Samadarsi, R., Nayak, A., & Dutta, D. (2023) · BioNanoScience · doi:10.1007/s12668-023-01275-y · Cited by 3 · see citing works
Self-citationda Silva, S. A., Souza, N. M. P., Trindade, G. A. D. M., Flauzino, M. W. P., de Oliveira, C. F., Brucker, N., Vinardell, M. P., Sari, M. H. M., Ferreira, L. M., & Reolon, J. B. (2026) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2026.112041 · Cited by 3 · see citing works
Alahmadi, S., Alanazi, M. M., Alasmari, F. F., Al-Qahtani, W. S., & Albasher, G. I. (2025) · Frontiers in Bioscience-Landmark · doi:10.31083/fbl26871 · Cited by 2 · see citing works
Torres, A. H. F., Soares, T. A., Dalcin, L. D. L., Rodrigues, G. F. D. S., Ribeiro, E. B., Honório‐França, A. C., & França, E. L. (2021) · Science of Advanced Materials · doi:10.1166/sam.2021.4048 · Cited by 2 · see citing works
Li, W., Chen, S., Wan, J., Chen, L., Xing, L., Gao, Z., & Chen, L. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1679774 · Cited by 1 · see citing works
Jie, L., Huang, H., Sha, L., Zhang, L., Wang, Y., & Cao, Y. T. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115924 · Cited by 1 · see citing works
Sabzevari, A., & Kakanejadifard, A. (2025) · Polymer Bulletin · doi:10.1007/s00289-025-05907-z · Cited by 1 · see citing works
Kamath, A. P., Kumar, L., Mutalik, S., Nayak, P. G., & Nandakumar, K. (2026) · ACS Omega · doi:10.1021/acsomega.5c12935 · Cited by 1 · see citing works
El‐Raghi, A. A., Elmorsy, E. M., Alyamani, S. A., Hifni, B. A., Al-Ghafari, A. B., Doghaither, H. A. A., Essawi, W. M., & Elzeer, A. A. (2026) · Cryobiology · doi:10.1016/j.cryobiol.2026.105634 · Cited by 1 · see citing works
Application of chitosan-based nanoparticles for the treatment of kidney diseases
Adeyomoye, O., Adetunji, C. O., Oyewole, O. A., Adetunji, J. B., Ogundolie, F. A., Mathew, J. T., & Inobeme, A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13997-0.00012-6
Aqil, A., Yasmeen, I., Parveen, I., Nadaf, A., Jiba, U., Adil, M., Hasan, N., Kesharwani, P., & Ahmad, F. J. (2025) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2025.177354
RetractedSustainable antioxidants, anti-UV, antiaging, and thermal stabilizers
Fatrıasarı, W., Bakshi, M. I., Javaid, S., & Ghozali, M. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-23806-2.00009-9
Molecular Insight of Mangiferin in Cancer Chemoprevention: A Review Article
Ateeb, M., Nazar, M. S., Zakki, S. A., Raza, A., & Hafeez, U. (2026) · Pakistan BioMedical Journal · doi:10.54393/pbmj.v9i2.1342
黄新余, Zhu, S., Feng, K., Wu, X., Wang, H., & Xu, D. (2026) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2026.115220
Zhou, Z., Li, W., Xu, Y., Wang, Y., Huang, W., Liu, Q., Pan, X., & Shi, C. (2026) · Journal of Materials Chemistry B · doi:10.1039/d6tb00672h
Molecular Insight of Mangiferin in Cancer Chemoprevention: A Review Article
Ateeb, M., Nazar, M. S., Zakki, S. A., Raza, A., & Hafeez, U. (2026) · Pakistan BioMedical Journal · doi:10.54393/pbmj.v9i3.1342
Mangiferin: A Natural Xanthone from Therapeutic Potential to In Silico Insights
Bhardwaj, S., Kapil, A., Gora, R., Garud, N., & Kumar, D. (2026) · In Silico Research in Biomedicine · doi:10.1016/j.insi.2026.100701
- Authors
- Samadarsi, R., & Dutta, D.
- Affiliations
- National Institute of Technology Durgapur (IN)
- Corresponding author
- Dutta, Debjani
- ORCID
- Dutta, Debjani
- Venue
- International Journal of Biological Macromolecules
- Publisher
- Elsevier BV
- Published
- 2020-05
- Volume
- 151
- Pages
- 36-46
- ISSN
- 0141-8130 (ISSN-L)
- OpenAlex
- W3006639456
- Cited by
- 57
- References
- 29
- Citations by year
- 2026: 9 · 2025: 14 · 2024: 11 · 2023: 6 · 2022: 8 · 2021: 8 · 2020: 1
- FWCI
- 6.37
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Biological Macromolecules (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Mangiferin and Mango Extracts
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Keywords
- mangiferin, chitosan nanoparticles, oxidative stress, antioxidant activity, renal epithelial cells, lipid peroxidation, protein oxidation, catalase, peroxidase, phase II antioxidant enzymes, bioavailability enhancement, kidney disease
- MeSH terms
- Antioxidants, Cell Survival, Cells, Cultured, Kidney, Models, Biological, Oxidation-Reduction, Spectrum Analysis, Reactive Oxygen Species, Oxidative Stress, Intracellular Space, Xanthones, Chitosan, Nanoparticles
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
