The management of diabetes mellitus by mangiferin: advances and prospects

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Suppression of methylglyoxal hyperactivity by mangiferin can prevent diabetes-associated cognitive decline in rats

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Up-regulation of glyoxalase 1 by mangiferin prevents diabetic nephropathy progression in streptozotocin-induced diabetic rats

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Mangiferin from <i>Salacia chinensis</i> Prevents Oxidative Stress and Protects Pancreatic <b> <i>β</i> </b> -Cells in Streptozotocin-Induced Diabetic Rats

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Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases

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Recent advances of nanomedicine-based strategies in diabetes and complications management: Diagnostics, monitoring, and therapeutics

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Mangiferin stimulates carbohydrate oxidation and protects against metabolic disorders induced by high-fat diets

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Mangiferin Alleviates Renal Interstitial Fibrosis in Streptozotocin-Induced Diabetic Mice through Regulating the PTEN/PI3K/Akt Signaling Pathway

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Mangiferin Attenuates Renal Fibrosis Through Down-Regulation of Osteopontin in Diabetic Rats: EFFECTS OF MANGIFERIN ON RENAL FIBROSIS IN DIABETES

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Pyruvate dehydrogenase kinase 4 mediates lipogenesis and contributes to the pathogenesis of nonalcoholic steatohepatitis

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Therapy of Type 2 Diabetes

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Topical administration of mangiferin promotes healing of the wound of streptozotocin-nicotinamide-induced type-2 diabetic male rats

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Anti-oxidative effect of mangiferin-chitosan nanoparticles on oxidative stress-induced renal cells

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C hina type 2 diabetes treatment status survey of treatment pattern of oral drugs users

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Clinical Pharmacology of Incretin Therapies for Type 2 Diabetes Mellitus: Implications for Treatment

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Acute Effects of a Polyphenol-Rich Leaf Extract of Mangifera indica L. (Zynamite) on Cognitive Function in Healthy Adults: A Double-Blind, Placebo-Controlled Crossover Study

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The impact of chemical engineering and technological advances on managing diabetes: present and future concepts

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Adhesive nanoparticles with inflammation regulation for promoting skin flap regeneration

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Mangiferin and its aglycone, norathyriol, improve glucose metabolism by activation of AMP-activated protein kinase

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Antidiabetic effect of mangiferin in combination with oral hypoglycemic agents metformin and gliclazide

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Comparative Pharmacokinetic Study of Mangiferin After Oral Administration of Pure Mangiferin and US Patented Polyherbal Formulation to Rats

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Acute and 28-day subchronic toxicity studies of mangiferin, a glucosylxanthone isolated from Mangifera indica L. stem bark

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Phytochemicals as modulators of β-cells and immunity for the therapy of type 1 diabetes: Recent discoveries in pharmacological mechanisms and clinical potential

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A novel strategy of nanotized herbal drugs and their delivery in the treatment of diabetes: Present status and future prospects

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The potential role of sodium glucose co‐transporter 2 inhibitors in the early treatment of type 2 diabetes mellitus

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Mangiferin mitigates diabetic cardiomyopathy in streptozotocin-diabetic rats

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Mangiferin suppresses endoplasmic reticulum stress in perivascular adipose tissue and prevents insulin resistance in the endothelium

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The Ayurvedic Medicine Salacia oblonga Attenuates Diabetic Renal Fibrosis in Rats: Suppression of Angiotensin II/AT1 Signaling

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High Serum Advanced Glycation End Products Are Associated with Decreased Insulin Secretion in Patients with Type 2 Diabetes: A Brief Report

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Natural dipeptidyl peptidase-IV inhibitor mangiferin mitigates diabetes- and metabolic syndrome-induced changes in experimental rats

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Mangiferin inhibits cell migration and angiogenesis via PI3K/AKT/mTOR signaling in high glucose‑ and hypoxia‑induced RRCECs

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Pharmacogenomics of Glinides

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In Vitro and In Vivo Effects of Norathyriol and Mangiferin on α-Glucosidase

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Mitigation of Insulin Resistance by Mangiferin in a Rat Model of Fructose-Induced Metabolic Syndrome Is Associated with Modulation of CD36 Redistribution in the Skeletal Muscle

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Pharmacokinetic and metabolomic analyses of Mangiferin calcium salt in rat models of type 2 diabetes and non-alcoholic fatty liver disease

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A comparison study of metformin only therapy and metformin combined with Chinese medicine jianyutangkang therapy in patients with type 2 diabetes: A randomized placebo-controlled double-blind study

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Mangiferin aglycone attenuates radiation‐induced damage on human intestinal epithelial cells

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Mangiferin inhibits high-fat diet induced vascular injury via regulation of PTEN/AKT/eNOS pathway

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Central nervous system activities of extract Mangifera indica L.

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An Amphiphilic PEGylated Peptide Dendron‐Gemcitabine Prodrug‐Based Nanoagent for Cancer Therapy

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Pyruvate dehydrogenase kinase 4 (PDK4) could be involved in a regulatory role in apoptosis and a link between apoptosis and insulin resistance

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Rhizome of <i>Anemarrhena asphodeloides</i> Counteracts Diabetic Ophthalmopathy Progression in Streptozotocin‐Induced Diabetic Rats

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Mangiferin Accelerates Glycolysis and Enhances Mitochondrial Bioenergetics

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Effects of Resveratrol and Mangiferin onPPARγandFALDHGene Expressions in Adipose Tissue of Streptozotocin-Nicotinamide-Induced Diabetes in Rats

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An Investigation of the Mechanism of Rapid Relief of Ulcerative Colitis Induced by Five-flavor Sophora Flavescens Enteric-coated Capsules Based on Network Pharmacology

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Positive interaction of mangiferin with selected oral hypoglycemic drugs: a therapeutic strategy to alleviate diabetic nephropathy in experimental rats

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Advances in newer basal and bolus insulins: impact on type 1 diabetes

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Effects of ethanol extract of bombax ceiba leaves and its main constituent mangiferin on diabetic nephropathy in mice

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Mangiferin ameliorates insulin resistance by inhibiting inflammation and regulatiing adipokine expression in adipocytes under hypoxic condition

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“DAK”, a traditional decoction in Palau, as adjuvant for patients with insufficient control of diabetes mellitus type II

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Oral treatment for diabetes using α-glucosidase inhibitors was a risk factor for chronic obstructive pulmonary disease: a cohort study

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People with Type Diabetes Mellitus (T1DM) self-reported views on their own condition management reveal links to potentially improved outcomes and potential areas for service improvement

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Effect of JYTK on Antioxidant Status and Inflammation in Patients With Type 2 Diabetes: A Randomized Double-Blind Clinical Trial

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Stimuli-responsive therapeutic systems for the treatment of diabetic infected wounds

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Advances in plant-derived C-glycosides: Phytochemistry, bioactivities, and biotechnological production

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Targeting Oxidative Stress and Inflammation in Intervertebral Disc Degeneration: Therapeutic Perspectives of Phytochemicals

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Ameliorative effects of mangiferin derivative TPX on insulin resistance via PI3K/AKT and AMPK signaling pathways in human HepG2 and HL-7702 hepatocytes

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Environment-triggered nanoagent with programmed gas release performance for accelerating diabetic infected wound healing

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Microneedles coated with composites of phenylboronic acid-containing polymer and carbon nanotubes for glucose measurements in interstitial fluids

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Stimuli‐Responsive NO Delivery Platforms for Bacterial Infection Treatment

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Mangiferin alleviates diabetic pulmonary fibrosis in mice via inhibiting endothelial-mesenchymal transition through AMPK/FoxO3/SIRT3 axis

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Enzyme‐Like Photocatalytic Octahedral Rh/Ag 2 MoO 4 Accelerates Diabetic Wound Healing by Photo‐Eradication of Pathogen and Relieving Wound Hypoxia

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From Nature to Nanotechnology: The Bioactivities of Mangiferin Explored

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“Multiomics” Analyses Combined with Systems Pharmacology Reveal the Renoprotection of Mangiferin Monosodium Salt in Rats with Diabetic Nephropathy: Focus on Improvements in Renal Ferroptosis, Renal Inflammation, and Podocyte Insulin Resistance

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In-depth analysis of the chemical composition, pharmacological effects, pharmacokinetics, and patent history of mangiferin

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Ferroptosis: a new strategy for Chinese herbal medicine treatment of diabetic nephropathy

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Mangiferin (mango) attenuates AOM-induced colorectal cancer in rat’s colon by augmentation of apoptotic proteins and antioxidant mechanisms

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Phospholipid-Based Topical Nano-Hydrogel of Mangiferin: Enhanced Topical Delivery and Improved Dermatokinetics

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Crosstalk between oxidative stress and inflammatory pathways: Natural therapeutic approaches for diabetic wound healing

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Endogenous stimuli-activatable photothermal therapy for bacterial infections

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Butterfly-shaped dendrimers with photosensitizer recruitment function for enhanced light-controlled precise cascaded ROS and NO release in multimodal diabetic foot ulcers infections treatment

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Signal pathways in the treatment of Rheumatoid Arthritis with traditional Chinese medicine

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Activation of Heme Oxygenase-1 by Mangiferin in Human Retinal Pigment Epithelial Cells Contributes to Blocking Oxidative Damage

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A GP130-Targeting Small Molecule, LMT-28, Reduces LPS-Induced Bone Resorption around Implants in Diabetic Models by Inhibiting IL-6/GP130/JAK2/STAT3 Signaling

Liu, Q., Wu, W., Yang, J., Wang, R.-B., Yuan, L., Peng, P., Zeng, M., & Yu, K. (2023) · Mediators of Inflammation · doi:10.1155/2023/9330439 · Cited by 16 · see citing works

Lipidomics of the erythrocyte membrane and network pharmacology to explore the mechanism of mangiferin from Anemarrhenae rhizoma in treating type 2 diabetes mellitus rats.

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Combination of mangiferin and T0901317 targeting autophagy promotes cholesterol efflux from macrophage foam cell in atherosclerosis

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Antioxidative myricetin-enriched nanoparticles towards acute liver injury

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Exploring the influence of polysaccharide on gastrointestinal stability, drug release and formation mechanism of nanoparticles in Zhimu and Huangbai herb pair decoction

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Antioxidant Potential of Ethiopian Medicinal Plants and Their Phytochemicals: A Review of Pharmacological Evaluation

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Progress in experimental models to investigate the in vivo and in vitro antidiabetic activity of drugs

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Nonmetallic N/C Nanozyme Performs Continuous Consumption of Glu for Inhibition of Colorectal Cancer Cells

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Transcriptome analysis and exploration of genes involved in the biosynthesis of secoiridoids in Gentiana rhodantha

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The effect of maternal dietary polyphenol consumption on offspring metabolism

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Study on Optimal Extraction and Hypoglycemic Effect of Quercetin

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Food Minor Bioactive Compounds of Polyphenolic and Polyprenolic Nature Are Promising Agents for the Prevention and Therapy of Non-Alcoholic Fatty Liver Disease

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Mangiferin promotes the osteogenic differentiation of human periodontal ligament stem cells via TGF‑β/SMAD2 signaling

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A novel fullerene-lysine derivative with noticeable ROS scavenging capabilities for improving type 2 diabetes mellitus

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Natural products in antidiabetic drug discovery: advances and opportunities

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Effective enrichment of glycated proteome using ultrasmall gold nanoclusters functionalized with boronic acid

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Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

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Unlocking Mangiferin: A Therapeutic Candidate Revolutionizing Liver Disease Therapy

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Herbal intervention targeting NLRP3 inflammasome in the treatment of liver diseases

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Mangiferin Induces Post-Implant Osteointegration in Male Diabetic Rats

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Tailored electronic properties of PdAu nanocatalysts via one-step electrodeposition for high-performance glucose sensors

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., S., Mazumder, A., Bansal, P., Pentela, B., Tyagi, P. K., & Khurana, N. (2024) · Journal of Natural Remedies · doi:10.18311/jnr/2024/36061 · Cited by 1 · see citing works

Actividad hipoglucémica de las hojas de Yaca (Artocarpus heterophyllus Lam)

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(2023) · PeerJ · doi:10.7287/peerj.14968v0.3/reviews/3

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(2023) · PeerJ · doi:10.7287/peerj.14968v0.1/reviews/1

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(2023) · PeerJ · doi:10.7287/peerj.14968v0.2/reviews/3

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(2023) · PeerJ · doi:10.7287/peerj.14968v0.2/reviews/1

Peer Review #3 of "Transcriptome analysis and exploration of genes involved in the biosynthesis of secoiridoids in Gentiana rhodantha (v0.1)"

(2023) · PeerJ · doi:10.7287/peerj.14968v0.1/reviews/3

Peer Review #2 of "Transcriptome analysis and exploration of genes involved in the biosynthesis of secoiridoids in Gentiana rhodantha (v0.1)"

(2023) · PeerJ · doi:10.7287/peerj.14968v0.1/reviews/2

Mangiferin and norathyriol acting on Alzheimer’s disease biomarkers: acetylcholinesterase, β-secretase (BACE-1), and amyloid β-peptide

de Oliveira, T. B., Galeriani, A. C. B., de Souza, J. R. R., Kawano, D. F., Trevisan, M. T. S., & Almeida, W. P. (2025) · Journal of Pharmacy and Pharmacology · doi:10.1093/jpp/rgaf055

Additional file 1 of Combination of mangiferin and T0901317 targeting autophagy promotes cholesterol efflux from macrophage foam cell in atherosclerosis

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Zhimu-Huangbai codecoction for the treatment of type II diabetes mellitus through its self-assembling nanoparticles

Nie, W., Jiang, M., Li, Y., Lan, J., Li, Z., Bi, Z., Gu, D., Zhang, M., Ding, Y., & Zhang, T. (2026) · Chinese Medicine · doi:10.1186/s13020-025-01290-z

Scavenging multiple reactive carbonyl species simultaneously by mangiferin and its aglycone norathyriol in vitro and in vivo

Du, R., Jiang, X., Wang, Y., Wang, J., Si, B., Chang, C. H., Lu, Y., & Lv, L. (2026) · Food Research International · doi:10.1016/j.foodres.2026.118639

Psidium guajava Leaf Phytochemical-Assisted One-Step Synthesis of Metformin/ZnO Nanoconjugate for Enhanced Solubility, Hydrophilicity, Biocompatibility, and Broad-Spectrum Therapeutic Potential

Mathew, D., Thomas, B., Sudheep, N. M., Varghese, S., Yesudas, V., Thomas, J. B., & Radhakrishnan, E. K. (2026) · Journal of Cluster Science · doi:10.1007/s10876-026-03057-4

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Fernández, M. C., Cruz, G. K. M., Zambrano, W. A. Z., Castro, N. L. M., Cuesta‐Rubio, O., Hernández, I. M., & Tocto-León, J. (2026) · Revista Colombiana de Química · doi:10.15446/rev.colomb.quim.v55n1.120573

Medicine–Food Homology Plants and Bioactive Compounds in Polyendocrine Metabolic Ovarian Syndrome: Multi-Target Mechanisms and Functional Food Potential—A Review

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Phytosomes: An Ideal way to Enhance Bioavailability of Mangiferin

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Aswal, S., Kumar, A., Chauhan, A., Semwal, R. B., Kumar, A., & Semwal, D. K. (2019) · Current Diabetes Reviews · doi:10.2174/1573399815666191004112023 · Cited by 24 · see citing works

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MANGIFERIN A NATURALLY OCCURRING GLUCOSYLXANTHONE OBTAINED BY SPRAY DRY WITH INCREASED SOLUBILITY USING HPMC, AS AN ACTIVE PHARMACEUTICAL INGREDIENT FOR NEW PHARMACOTHERAPEUTIC APPLICATIONS

González, A. F., Gaitén, Y. I. G., Delgado, R., Scull, R., Pieters, L. A. C., Kiekens, F., Baars, A., Peña, C. M. G., Nogueira, A., & Berghe, W. V. (2018) · Proceedings for Annual Meeting of The Japanese Pharmacological Society · doi:10.1254/jpssuppl.wcp2018.0_po4-8-32

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Maulina, D., & Estuningtyas, A. (2020) · Journal of Critical Reviews