Comorbid painful physical symptoms and depression: prevalence, work loss, and help seeking
Abstract
Background Painful physical symptoms (PPS) are frequent in patients with Major Depressive Episode (MDE). Here, the 12-month prevalence and sociodemographic characteristics of PPS were examined taking into account somatic comorbidity; quantitative and qualitative aspects of MDE with or without PPS were investigated as well as their impact on work loss days (WLD). Finally, help seeking and delay in help seeking were explored.Methods In a cross-sectional, population-based study, a representative random sample of non-institutionalised adults from Belgium, France, Germany, Italy, the Netherlands and Spain (N = 21,425) was interviewed using the World Mental Health Composite Diagnostic Interview (CIDI 3.0 of the WHO).Results PPS were reported by 29% of respondents without MDE and by 50% in those with MDE. Female gender, higher age and lower educational level were predictive of PPS. PPS were more frequent in more severely depressed patients but no qualitative differences were found in MDE with and MDE without PPS. An additive effect of MDE and PPS was found on the WLD score. Whether a comorbid somatic disorder was present or not did not change the findings. Finally, respondents with MDE and PPS had lower rates of help seeking for emotional reasons and show a trend to delay their help seeking longer.Limitations The most important limitation of this study was its reliance on self-report data about somatic disorders.Conclusion Approximately one in two persons with a mood disorder also reported the presence of PPS. MDE and PPS result in decreased productivity and in lower rates of help seeking.
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Previous studies report that patients with co-existing depression and pain tend to delay seeking help.
“and that patients with co-existing depression and pain tend to delay seeking help (Demyttenaere et al., 2006).”
From Presence and predictors of pain in depression: Results from the FINDER study (2010) · cites this paper as Demyttenaere et al., 2006
Previous findings show an inverse relationship between educational attainment and pain.
“These con fi rm previous fi ndings of an inverse relationship betweeneducational attainmentand pain (Demyttenaereetal., 2006).”
From Presence and predictors of pain in depression: Results from the FINDER study (2010) · cites this paper as Demyttenaere et al., 2006
Previous studies show that older age is associated with increased pain severity.
“These latter fi ndings are consistent with previous studies that older age is associated with increased pain severity (Bair et al., 2004; Demyttenaere et al., 2006).”
From Presence and predictors of pain in depression: Results from the FINDER study (2010) · cites this paper as Demyttenaere et al., 2006
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- Authors
- Demyttenaere, K., Bonnewyn, A., Bruffaerts, R., Brugha, T., De Graaf, R., & Alonso, J.
- Affiliations
- Universitair Ziekenhuis Leuven (BE)
- Corresponding author
- Demyttenaere, Koen
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2006-06
- Volume
- 92
- Issue
- 2-3
- Pages
- 185-193
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W2145151645
- Cited by
- 217
- References
- 33
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 13 · 2023: 5 · 2022: 10 · 2021: 11 · 2020: 1 · 2019: 4 · 2018: 8 · 2017: 13 · 2016: 8 · 2015: 11 · 2014: 14 · 2013: 25 · 2012: 14
- FWCI
- 9.16
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- Leicester Research Archive (University of Leicester) (submittedVersion)
- Funders
- John D. and Catherine T. MacArthur Foundation
- GlaxoSmithKline
- World Health Organization
- European Commission
- National Institutes of Health (5r13mh066849-04, 5r01mh069864-04)
- Pan American Health Organization
- National Institute of Mental Health (1R13 MH066849, MH069864)
- National Institute on Drug Abuse (R01DA016558)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Keywords
- major depressive episode, depression, somatic comorbidity, work loss, help-seeking, help-seeking delay, prevalence, sociodemographic predictors, depression severity, productivity loss
- MeSH terms
- Adolescent, Adult, Aged, Chronic Disease, Cross-Sectional Studies, Depressive Disorder, Major, Major Depressive Disorder, Female, Humans, Male, Middle Aged, Pain, Pain Measurement, Patient Acceptance of Health Care, Population Surveillance, Surveys and Questionnaires, Severity of Illness Index, Unemployment, Comorbidity, Prevalence
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