CoChat
Sign Up
Cited by 86Treatment of Major DepressionPhysical Activity and HealthAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Exercise and severe depression: preliminary results of an add-on study.

Schuch, F.B., Vasconcelos-Moreno, M.P., Borowsky, C., Fleck, M.P.·2011·Journal of Affective Disorders
DOI 10.1016/j.jad.2011.04.030
Open this paper in CoChat — free account

Abstract

Background Physical exercise has been extensively researched as a therapeutic option for treatment of major depression.Methods In a randomized controlled trial, we analyze the effects of aerobic physical exercise as an add-on strategy for treatment of severe depressed inpatients. The exercise has a "Dose" of 16.5 kcal/kg/week, three times a week during all the hospitalization.Results Our preliminary results show that there is no significant difference in scores of Hamilton in the second week between groups (Mean[SD]=8.2[5.96] × 11.18[5.03], p=0.192). However, there is a significant reduction in Hamilton scores of patients in exercise group at discharge (Mean[SD]=5.93[4.46] × 9.45[3.56], p=0.041). Regarding Quality of Life (QoL), no significant difference were found between groups in the second week in physical domain (Mean[SD]=56.98[8.96] × 54.54[9.18], p=0.511) and psychological domain (Mean[SD]=50.88[13.88] × 42.04[12.42], p=0.106). However, there is a significant difference in psychological domain (Mean[SD]=55.88[9.92] v 41.66[13.04], p=0.004) and a trend but no statistical significance in the physical (Mean[SD]=58.80[9.14] × 52.12[8.70], p=0.07) at discharge.Limitations Many patients receive different treatment strategies, like ECT (1 patient at exercise group × 3 at control group). Other limitation is the small number of participants included until this moment.Conclusion Our preliminary results suggest that physical exercise could be a feasible and effective add-on strategy for treatment of severe depressed inpatients, improving their depressive symptoms and QoL.

Integrity signals

Registry

Crossref · 10.1016/j.jad.2011.04.030

Cites

31 of 31 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The inclusion of AE to a traditional antidepressant intervention has been shown to have a greater impact on reducing depressive symptoms in patients with MDD than antidepressant treatment alone.

    “Additionally, the inclusion of AE to a traditional antidepressant intervention has been shown to have greater impact on reducing depressive symptoms in patients with MDD, than antidepressant treatment alone (Knubben et al., 2007; Schuch et al., 2011; Legrand and Neff, 2016).”

    From Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment (2016) · cites this paper as Schuch et al., 2011

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Schuch, F. B., Vasconcelos-Moreno, M. P., Borowsky, C., & Fleck, M. P.
Affiliations
  • Universidade Federal do Rio Grande do Sul (BR)
  • Hospital de Clínicas de Porto Alegre (BR)
Corresponding author
Schuch, F.B.
ORCID
Venue
Journal of Affective Disorders
Publisher
Elsevier BV
Published
2011-10
Volume
133
Issue
3
Pages
615-618
ISSN
0165-0327 (ISSN-L)
DOI
10.1016/j.jad.2011.04.030
OpenAlex
W2002609178
Cited by
86
References
30
Citations by year
2026: 5 · 2025: 3 · 2024: 6 · 2022: 7 · 2021: 10 · 2020: 6 · 2019: 1 · 2018: 6 · 2017: 6 · 2016: 9 · 2015: 10 · 2014: 6 · 2013: 8 · 2012: 3
FWCI
3.98
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Journal of Affective Disorders (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Hospital de Clínicas de Porto Alegre
  • Fundação Instituto de Pesquisas Econômicas
Topics
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
physical activity, aerobic exercise, severe depression, major depressive disorder, hospitalized patients, adjunctive therapy, quality of life, depressive symptoms, exercise dose, electroconvulsive therapy
MeSH terms
Adult, Energy Intake, Depression, Major Depressive Disorder, Depressive Disorder, Exercise Therapy, Female, Humans, Male, Middle Aged, Quality of Life, Exercise, Treatment Outcome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review