Physical activity and suicidal ideation: A systematic review and meta-analysis
Open accessAbstract
Background A potential approach to suicide prevention that has not been closely examined, but which holds promise in terms of widespread dissemination without major side-effects, is physical activity (PA). This systematic review and meta-analysis set out to: (a) explore associations between PA and suicidal ideation (SI) levels, and (b) investigate the effect of PA interventions on SI.Methods Major electronic databases were searched from inception up to 05/2017 to identify quantitative studies reporting an association between PA and SI. A quantitative correlates synthesis and random effects meta-analysis were conducted.Results Fourteen of 21 studies in adults (67%) (n = 130,737), 7/14 (50%) in adolescents (n = 539,170) and 2/3 (67%) in older adults (n = 50,745) found a significant negative association between PA- and SI-levels. Pooled adjusted meta-analysis of 14 effect sizes over eight studies and 80,856 people found that those who were "active" versus those who were "inactive" were less likely to have SI (OR = 0.87, 95%CI = 0.76-0.98). Additionally, meeting PA guidelines conferred a significant protective effect against SI (OR = 0.91, 95%CI = 0.51-0.99, P = 0.03; N studies = 3, n people = 122,395), while not meeting guidelines was associated with increased SI (OR = 1.16, 95%CI = 1.09-1.24, P < 0.001; N = 4, n = 78,860). Data from the intervention studies (N = 3, n = 121) was mixed and limited.Limitations Our findings are based mainly on cross-sectional studies, while the majority of studies did not include a rigorous physical activity assessment.Conclusions The current study suggests that higher PA levels are associated with lower SI. However, the associations observed need to be confirmed in prospective observational studies and controlled trials.
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Individuals who reported meeting current physical activity guidelines were significantly less likely to report suicidal ideation, while individuals who did not meet current physical activity guidelines were significantly more likely to report suicidal ideation.
“Further, individuals who reported meeting current physical activity guidelines were significantly less likely to report suicidal ideation, while individuals who did not meet current physical activity guidelines were significantly more likely to report suicidal ideation [148].”
From The Cyclical Battle of Insomnia and Mental Health Impairment in Firefighters: A Narrative Review (2024) · cites this paper as [148]
There is a significant negative association between physical activity and suicidal ideation.
“While the results are based on cross-sectional data, there was a significant negative association between physical activity and suicidal ideation.”
From The Cyclical Battle of Insomnia and Mental Health Impairment in Firefighters: A Narrative Review (2024) · cites this paper as [148]
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Jia, C.-X., Li, S.-B., Han, M., & Bo, Q.-G. (2015) · OMEGA - Journal of Death and Dying · doi:10.1177/0030222815576126 · Cited by 6 · see citing works
Jeong, K. C., Koo, K.-M., & Kim, C.-J. (2016) · Indian Journal of Science and Technology · doi:10.17485/ijst/2016/v9i25/97186 · Cited by 3 · see citing works
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Physical Exercise in Major Depression: Reducing the Mortality Gap While Improving Clinical Outcomes
Belvederi Murri, M., Ekkekakis, P., Magagnoli, M., Zampogna, D., Cattedra, S., Capobianco, L., Serafini, G., Calcagno, P., Zanetidou, S., & Amore, M. (2019) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2018.00762 · Cited by 163 · see citing works
Physical exercise for late-life depression: Effects on symptom dimensions and time course.
Murri, M. B., Ekkekakis, P., Menchetti, M., Neviani, F., Trevisani, F., Tedeschi, S., Latessa, P. M., Nerozzi, E., Ermini, G., Zocchi, D., et al. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.01.004 · Cited by 106 · see citing works
The Cyclical Battle of Insomnia and Mental Health Impairment in Firefighters: A Narrative Review
Holland-Winkler, A. M., Greene, D. R., & Oberther, T. J. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13082169 · Cited by 9 · see citing works
- Authors
- Vancampfort, D., Hallgren, M., Firth, J., Rosenbaum, S., Schuch, F. B., Mugisha, J., Probst, M., Van Damme, T., Carvalho, A. F., & Stubbs, B.
- Affiliations
- KU Leuven (BE)
- Karolinska Institutet (SE)
- University of Manchester (GB)
- Black Dog Institute (AU)
- Hospital de Clínicas de Porto Alegre (BR)
- Butabika Hospital (UG)
- National Health Service (GB)
- Corresponding author
- Vancampfort, Davy
- ORCID
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2018-01
- Volume
- 225
- Pages
- 438-448
- ISSN
- 0165-0327 (ISSN-L)
- OpenAlex
- W2748449302
- Cited by
- 255
- References
- 92
- Citations by year
- 2026: 24 · 2025: 36 · 2024: 41 · 2023: 31 · 2022: 30 · 2021: 30 · 2020: 32 · 2019: 23 · 2018: 6 · 2017: 1
- FWCI
- 2.57
- Type
- journal article
- Language
- en
- Open access
- green
- kclpure.kcl.ac.uk
- Licence
- cc-by-nc-nd
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- Locations
- Journal of Affective Disorders (publishedVersion)
- PubMed (publishedVersion)
- Figshare (submittedVersion)
- Research Portal (King's College London) (submittedVersion, cc-by-nc-nd)
- Lirias (submittedVersion)
- Research Explorer (The University of Manchester) (submittedVersion)
- Funders
- National Institute for Health and Care Research (ICA-CL-2017-03-001, NIHR-INF-0685)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- physical activity, suicidal ideation, suicide prevention, physical activity interventions, physical activity guidelines, physical inactivity, adolescents, older adults, adults
- MeSH terms
- Suicide Prevention, Adolescent, Adult, Age Factors, Aged, Attitude to Health, Cross-Sectional Studies, Humans, Middle Aged, Motor Activity, Prospective Studies, Suicide, Health Behavior, Exercise, Young Adult, Suicidal Ideation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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