Suicide in older adults
Open accessAbstract
This article makes the case that late-life suicide is a cause for great concern that warrants ongoing attention from researchers, health care providers, policy makers, and society at large. It reviews the evidence for factors that place older adults at risk for suicide, or protect them from it. The authors introduce the notion that suicide preventive interventions target individuals or groups at different levels of risk at different points on the developmental trajectory toward death by suicide, offering examples and recommending their strategic, combined application to create an effective, community-level response to the mounting problem of suicide in older adults.
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Claims the paper makes
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- Findingnone given
For both black and white women, suicide rates rise through midlife and fall thereafter.
“For both black and white women, rates rise through midlife and fall thereafter; black men experience two peaks of risk, one in young adulthood and the second in old age.”
Quote in the paperNot a substantial claim - Findingnone given
Reductions in suicide rates among youth, young adults, and those over age 65 largely accounted for the US decrease.
“Reductions in rates among youth, young adults, and those over age 65 largely accounted for the decrease.”
Quote in the paperNot a substantial claim - Findingnone given
Black men experience two peaks of suicide risk, one in young adulthood and another in old age.
“For both black and white women, rates rise through midlife and fall thereafter; black men experience two peaks of risk, one in young adulthood and the second in old age.”
Quote in the paperNot a substantial claim - Interpretationreasoning
Longitudinal cohort studies with enough suicides for meaningful analyses are unfeasible because suicide is a relatively rare event.
“Longitudinal cohort studies in which sufficient numbers die by suicide to allow meaningful analyses are unfeasible because suicide is a relatively rare event.”
Quote in the paperSubstantial claim - Interpretationnone given
Risk factors taken individually give weak guidance for suicide prevention because their ability to predict individual suicide deaths is poor.
“Taken individually, however, risk factors offer relatively weak guidance for implementation of successful suicide prevention initiatives because, at the individual level, their ability to predict who will die by suicide is so poor.”
Quote in the paperSubstantial claim
- Interpretationreasoning
Suicide in older adults should be understood from a public health perspective as a developmental process shaped over time by risk and protective factors.
“We argue then from a public health perspective for understanding suicide as a developmental process to which risk and protective factors contribute in defining a trajectory to suicide over time.”
Quote in the paperNot a substantial claim - Study design and conductreasoning
The psychological autopsy method is subject to recall bias and other limitations inherent to retrospective data collection.
“Although subject to recall bias and other limitations inherent to retrospective data collection, the PA approach has advantages as well”
Quote in the paperNot a substantial claim - Premisecitation
Demographers estimate that by 2030 over 71 million US citizens will be age 65 or older, or 20 percent of the US population.
“Demographers estimate that by the year 2030 over 71 million United States citizens will be age 65 or older, or 20 percent of the US population (3).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [3] The Merck Company Foundation
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- Premisecitation
Record linkage studies consistently found individuals with malignancies other than common skin cancers at approximately twice the suicide risk of those without.
“record linkage studies have consistently found that individuals with malignancies (other than common skin cancers) are at approximately 2 times greater risk for suicide than those without (25).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [25] Harris, 1994, Suicide as an outcome for medical disorders, Medicine (Baltimore) source
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- Premisecitation
In a case-control comparison of suicides over age 50 with living matched controls, any impairment in instrumental activities of daily living was significantly associated with suicide case status independent of physical and mental health disorder diagnoses.
“in a case controlled comparison of suicides over age 50 years with living demographically matched controls, our group found in multivariate analyses that the presence of any impairment in instrumental activities in daily living (IADLs) was significantly associated with suicide case status independent of the effects of physical and mental health disorder diagnoses (21).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [21] Conwell, 2009, Health status and suicide in the second half of life, Int J Geriatr Psychiatry source
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- Interpretationnone given
Even in longitudinal studies, the time between a subject's most recent assessment and death would require retrospective analysis.
“even in longitudinal studies the time between a subject's most recent assessment and death, a critical period for understanding the more immediate precipitants of suicidal behavior, would require retrospective analysis.”
Quote in the paperSubstantial claim - Interpretationreasoning
Because base rates of physical illness and disability are high in older adults, their usefulness for identifying individual elders who need intervention is weak.
“Because the base rates of physical illness and disability are so high in this population, however, their usefulness in identifying individual elders who warrant intervention is weak.”
Quote in the paperNot a substantial claim - Premisecitation
Cognitive deficits in later life have been linked to suicide.
“Cognitive deficits in later life have also been linked to suicide.”
Quote in the paperSubstantial claim - Premisecitation
Other biological and epidemiologic data provide preliminary evidence that dementia is associated with increased suicide risk in older adults.
“Other biological (24) and epidemiologic (22) data provide at least preliminary evidence that dementia too is associated with increased risk of suicide in older adults.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [24] Rubio, 2001, Suicide and Alzheimer’s pathology in the elderly: a case–control study, Biol Psychiatry source
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- cites [22] Erlangsen, 2008, Hospital-diagnosed dementia and suicide: a longitudinal study using prospective, nationwide register data, Am J Geriatr Psychiatry source
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- Study design and conductcitation
Studies demonstrate the validity of the psychological autopsy method.
“Reinforced by studies demonstrating the validity of the PA method (5, 6)”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [5] Conner, 2001, The validity of proxy-based data in suicide research: a study of patients 50 years of age and older who attempted suicide. II. Life events, social support, and suicidal behavior, Acta Psychiatr Scand source
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- cites [6] Conner, 2001, The validity of proxy-based data in suicide research: a study of patients 50 years of age and older who attempted suicide. I. Psychiatric diagnoses, Acta Psychiatr Scand source
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- Premisecitation
Elderly suicide decedents commonly communicated a belief that they had cancer that autopsy did not confirm, without other indication of thought disorder or cognitive impairment.
“elderly suicide decedents commonly communicated a belief to others that they had cancer that on autopsy was unconfirmed. Yet there was no other indication of thought disorder or cognitive impairment (28).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [28] Conwell, 1990, Suicide and cancer in late life, Hosp Community Psychiatry
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- Interpretationreasoning
Frontal executive function may be particularly pertinent to suicidal behavior in older adulthood because of its role in managing stressful circumstances.
“Frontal executive function may be particularly pertinent to suicidal behavior in older adulthood because of its role in effective management of stressful circumstances.”
Quote in the paperSubstantial claim - Interpretationcitation
Perceived health status may ultimately prove more salient to late life suicide and its prevention than objective measures, as observed for natural death and all-cause mortality.
“Perceived health status may ultimately prove to have greater salience to late life suicide and its prevention than objective measures, just as has been observed in association with natural death and all-cause mortality (29).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [29] Kaplan, 1988, Subjective state of health and survival in elderly adults, J Gerontol source
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- Interpretationcitation
The psychological autopsy method may be poorly suited to study dementia and delirium because their signs and symptoms are less likely to be apparent in community settings to family and proxy informants.
“The PA method may be poorly suited to the study of dementia and delirium the signs and symptoms of which, particularly early in the course of illness when the patient may be at relatively greater risk (22, 23), are less likely to be apparent in community settings to family members and other proxy informants.”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [22] Erlangsen, 2008, Hospital-diagnosed dementia and suicide: a longitudinal study using prospective, nationwide register data, Am J Geriatr Psychiatry source
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- cites [23] Haw, 2009, Dementia and suicidal behavior: a review of the literature, Int Psychogeriatr source
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- Interpretationcitation
The Ahearn finding supports the hypothesis that underlying vascular disease may predispose to late life depressive illness and suicidal behavior.
“supporting the hypothesis that underlying vascular disease may predispose to late life depressive illness and suicidal behavior (38).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [38] Alexopoulos, 1997, Vascular depression hypothesis, Arch Gen Psychiatry source
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- Premisecitation
Conditions such as HIV/AIDS, epilepsy, Huntington's disease, multiple sclerosis, renal and peptic ulcer disease, heart and lung diseases, spinal cord injury, and systemic lupus erythematosus have been associated with increased suicide risk in some studies.
“Other diverse conditions such as HIV/AIDS, epilepsy, Huntington's disease and multiple sclerosis, renal and peptic ulcer disease, heart and lung diseases, spinal cord injury and systemic lupus erythematosus have also been found to be associated with increased suicide risk in some studies (25-27).”
Quote in the paperNot a substantial claim0 of 3 sources checked- cites [25] Harris, 1994, Suicide as an outcome for medical disorders, Medicine (Baltimore) source
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- cites [26] Juurlink, 2004, Medical illness and the risk of suicide in the elderly, Arch Intern Med source
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- cites [27] Quan, 2002, Association between physical illness and suicide among the elderly, Soc Psychiatry Psychiatr Epidemiol source
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- Interpretationreasoning
The counterintuitive finding of lower dementia or delirium in suicides is likely explained by high rates of cognitive disorders and confusional states in hospitalized and terminally ill elders.
“a counterintuitive finding not observed in the other studies and likely explained by high rates of cognitive disorders and confusional states in hospitalized and terminally ill elders.”
Quote in the paperSubstantial claim - Premisereasoning
Major depression is most closely associated with suicide in older adults.
“In particular, major depression is most closely associated.”
Quote in the paperSubstantial claim - Premisereasoning
The prevalence of substance use disorders in older adult suicides is highly variable, reflecting differences in measures, populations, and socio-cultural context.
“The prevalence of substance use disorders was highly variable in these studies, reflecting differences in the measures used, the populations examined, and their socio-cultural context.”
Quote in the paperNot a substantial claim - Premisecitation
Other reports support a link between suicidal behavior in older adults and brain pathology.
“Other reports support a link between suicidal behavior in older adults and brain pathology.”
Quote in the paperNot a substantial claim - Premisecitation
Psychological autopsy case-control studies provide remarkably consistent findings.
“a variety of investigators have applied it in case control studies that provide remarkably consistent findings (7-21).”
Quote in the paperNot a substantial claim0 of 10 sources checked- cites [7] Barraclough, 1971, Suicide in the elderly: recent developments in psychogeriatrics, Br J Psychiatry
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- cites [8] Carney, 1994, Suicide over 60: the San Diego study, J Am Geriatr Soc source
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- cites [9] Chiu, 2004, Elderly suicide in Hong Kong—a case-controlled psychological autopsy study, Acta Psychiatr Scand source
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- cites [10] Clark, 1991
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- cites [11] Conwell, 1996, Relationships of age and axis I diagnoses in victims of completed suicide: a psychological autopsy study, Am J Psychiatry source
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- cites [12] Harwood, 2001, Psychiatric disorder and personality factors associated with suicide in older people: a descriptive and case–control study, Int J Geriatr Psychiatry source
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- cites [13] Henriksson, 1995, Mental disorders in elderly suicide, Int Psychogeriatr source
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- cites [14] McGirr, 2008, Impulsive–aggressive behaviours and completed suicide across the life cycle: a predisposition for younger age of suicide, Psychol Med source
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- cites [15] Waern, 2002, Mental disorder in elderly suicides: a case–control study, Am J Psychiatry source
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- cites [16] Rubenowitz, 2001, Life events and psychosocial factors in elderly suicides—a case–control study, Psychol Med source
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- Premisecitation
Relative risks for suicide associated with these physical conditions are about 1.5 to 4 times higher.
“Relative risks for suicide associated with these conditions are in the range of 1.5 to 4 times higher.”
Quote in the paperNot a substantial claim - Premisecitation
Dombrovski and colleagues reported that elderly suicidal depressives performed worse on frontal executive function, memory, and attention tests than non-suicidal elderly depressives.
“Dombrovski and colleagues, for example, have reported that elderly suicidal depressives performed worse on measures of frontal executive function as well as memory and attention tests than did non-suicidal elderly depressives (32).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [32] Dombrovski, 2008, Cognitive performance in suicidal depressed elderly: preliminary report, Am J Geriatr Psychiatry source
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- Premisecitation
Ahearn and colleagues reported that elderly depressives with lifetime histories of suicide attempts had significantly more subcortical gray matter hyperintensities on MRI than carefully matched depressives with no previous suicide attempt history.
“Ahearn and colleagues, for example, reported that elderly depressives with lifetime histories of suicide attempts had significantly more subcortical gray matter hyperintensities on MRI than carefully matched depressives with no previous suicide attempt history (37)”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [37] Ahearn, 2001, MRI correlates of suicide attempt history in unipolar depression, Biol Psychiatry source
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- Premisecitation
Several studies suggest pain may be especially important for suicide among older men.
“several studies suggest that it may be an especially important issue among older men.”
Quote in the paperNot a substantial claim - Premisecitation
Family discord and employment change distinguished suicides from controls over age 50 even after adjusting for socio-demographic characteristics and mental disorders.
“Our group also has reported that family discord and employment change distinguished suicides from controls over the age of 50 years even after adjusting for socio-demographic characteristics and mental disorders (18).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [18] Duberstein, 2004, Suicide at 50 years of age and older: perceived physical illness, family discord and financial strain, Psychol Med source
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- Premisecitation
Sirey and colleagues found a stronger association between suicidal ideation and chronic pain among older adult men receiving home delivered meals than women.
“Sirey and colleagues found a stronger association between suicidal ideation and chronic pain among older adult men receiving home delivered meals than women (30)”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [30] Sirey, 2008, Depressive symptoms and suicidal ideation among older adults receiving home delivered meals, Int J Geriatr Psychiatry source
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- Premisecitation
Physical ill health and functional impairments contribute to suicide risk in later life.
“In addition to psychiatric illness, physical ill health and functional impairments contribute to risk for suicide in later life.”
Quote in the paperSubstantial claim - Interpretationown data
The perceived meaning of physical illnesses, their impact on function, pain, and threats to autonomy and personal integrity likely play pivotal roles in late life suicide.
“it is likely that the perceived meaning of those illnesses, their impact on function, pain, and threats to autonomy and personal integrity play pivotal roles as well.”
Quote in the paperSubstantial claim - Premiseown data
The odds of an older adult having any Axis I diagnosis were between 44 and 113 times higher for suicides than matched controls.
“the odds of an older adult having any Axis I diagnosis were between 44 and 113 times higher for suicides than matched controls.”
Quote in the paperSubstantial claim - Interpretationreasoning
Wide variation between studies in the strength of associations can be accounted for by methodologic differences, including choice of control group.
“The wide variation between studies in the strength of associations observed can also be accounted for by methodologic differences, including the choice of control group.”
Quote in the paperSubstantial claim - Premisenone given
Primary psychotic disorders including schizophrenia, schizoaffective illness, and delusion disorder, as well as anxiety disorders, tend to be present in lower proportions among older adult suicides.
“Primary psychotic disorders including schizophrenia, schizoaffective illness, and delusion disorder, as well as anxiety disorders, tend to be present in lower proportions.”
Quote in the paperNot a substantial claim - Premisecitation
Psychological autopsy studies clearly and consistently demonstrate a role for social factors in the pathogenesis and prevention of suicide in older adults.
“PA studies clearly and consistently demonstrate a role for social factors in the pathogenesis, and therefore prevention, of suicide in older adults as well.”
Quote in the paperSubstantial claim - Interpretationcitation
As the number of acute and chronic conditions increases, cumulative suicide risk increases.
“as the number of an individual's acute and chronic conditions increases, so does his cumulative risk.”
Quote in the paperSubstantial claim - Premisenone given
Stressful life events preceding death by suicide tend to be more numerous and severe among suicides than controls.
“It is clear that stressful life events preceding death by suicide tend to be more numerous and severe among suicides than controls.”
Quote in the paperSubstantial claim - Premisecitation
Rates of problem drinking differ markedly between East and West.
“Rates of problem drinking, for example differ markedly in the East (9) and West (21).”
Quote in the paperNot a substantial claim0 of 2 sources checked - Interpretationreasoning
The most salient stressful life events for late life suicide are those associated with aging: threats from ill health and functional impairment, and losses through bereavement or rupture of relationships.
“The events most salient to suicide in later life are those associated with aging – threats associated with ill health and functional impairment as noted above, losses through bereavement or rupture of relationships with family members and other sources of support.”
Quote in the paperSubstantial claim - Premisecitation
Juurlink and colleagues reported that the association between severe pain and suicide was somewhat stronger for men (OR = 9.9) than women (OR = 3.3).
“Juurlink and colleagues, for example, reported that the association between severe pain and suicide was somewhat stronger for men (OR = 9.9) than women (OR = 3.3) (26).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [26] Juurlink, 2004, Medical illness and the risk of suicide in the elderly, Arch Intern Med source
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- Premisereasoning
Relationships characterized by perceived burdensomeness or other forms of interpersonal discord will not protect against suicide.
“Thus, relationships characterized by perceived burdensomeness, or other forms of interpersonal discord, will not protect against suicide.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [43] Van Orden, 2010, The interpersonal theory of suicide, Psychol Rev source
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- Premisecitation
Thwarted belongingness stems from the fundamental need for connectedness posited by Baumeister and Leary, reflected in social isolation indices linked with late life suicide such as living alone, loss of spouse, loneliness, and low social support.
“The construct of thwarted belongingness stems from the fundamental need for connectedness posited by Baumeister and Leary as the “need to belong (44), reflected in indices of social isolation that have been empirically linked with late life suicide such as living alone, loss of spouse, loneliness, and low social support.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [44] Baumeister, 1995, The need to belong: desire for interpersonal attachments as a fundamental human motivation, Psychol Bull source
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- Interpretationnone given
The limitations of risk and protective factors as prediction and prevention tools are related in part to risk states being dynamic and waxing and waning over short periods.
“The limitations of risk and protective factors as tools to predict and prevent suicide are related in part to the fact that risk states are dynamic -- they wax and wane over short periods of time.”
Quote in the paperNot a substantial claim- Rests on an assumption: Risk states are dynamic and wax and wane over short periods of time.
- Interpretationcitation
The construct of social connectedness may be especially important for understanding late life suicide and its prevention.
“On both theoretical and empirical bases, the construct of “social connectedness” may be especially important when understanding late life suicide and its prevention.”
Quote in the paperSubstantial claim - Premisecitation
The influence of social connectedness on risk for death is comparable to or greater than that of well-established risk factors such as smoking, obesity, and physical inactivity.
“they noted that the influence of a social connectedness on risk for death is comparable to or greater than that associated with well-established risk factors such as smoking, obesity, and physical inactivity.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [40] Holt-Lunstad, 2010, Social relationships and mortality risk: a meta-analytic review, PLoS Med source
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- Premisecitation
Holt-Lunstad and colleagues' meta-analysis of 148 studies found a 50 percent increased likelihood of survival for participants with stronger social relationships.
“Holt-Lunstad and colleagues in a recent meta-analytic review of 148 studies to determine the extent to which social relationships influence risk for mortality (40). They found that overall there was a 50 percent increased likelihood of survival for participants with stronger social relationships.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [40] Holt-Lunstad, 2010, Social relationships and mortality risk: a meta-analytic review, PLoS Med source
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- Premisecitation
Among older adults, the ratio is about four attempts per completed suicide.
“Among older adults attempts are far less common, yielding a ratio of perhaps four attempts per completed suicide (56).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [56] McIntosh, 1994
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- Premisecitation
Anankastic (obsessional) and anxious traits significantly distinguished suicides from elder natural death controls in one study.
“anankastic (obsessional) and anxious traits were shown to significantly distinguish suicides from elder natural death controls in one study (12)”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [12] Harwood, 2001, Psychiatric disorder and personality factors associated with suicide in older people: a descriptive and case–control study, Int J Geriatr Psychiatry source
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- Premisecitation
According to the Interpersonal Theory, only connections that contribute to individuals' need to belong-connections that create positive interactions and feelings of being cared about-will be protective.
“However, according to the theory, only connections that contribute to individuals' need to belong—connections that create positive interactions and feelings of being cared about—will be protective.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [43] Van Orden, 2010, The interpersonal theory of suicide, Psychol Rev source
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- Interpretationreasoning
Suicide is better understood as a developmental process that evolves over longer periods.
“Suicide therefore, is better understood as a developmental process that evolves over longer periods.”
Quote in the paperNot a substantial claim - Premisecitation
A public health approach proposes that interventions aimed at more distal and intermediate factors and stages of the suicidal process may save more lives than interventions focused only on high-risk individuals.
“Indeed, it would propose that interventions targeting more distal and intermediate factors and stages of the process may result in more lives saved than those restricting focus to higher risk individuals (53, 54).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [53] Rose, 1992
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- cites [54] Knox, 2004, If suicide is a public health problem, what are we doing to prevent it?, Am J Public Health source
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- Interpretationreasoning
Few studies have examined neurobiological systems in suicidal older adults because high rates of medication use and medical comorbidity complicate interpretation.
“However, few studies have examined neurobiological systems in suicidal older adults because high rates of medication use and medical comorbidity in older adult suicides and attempted suicides complicate interpretation and findings in such studies.”
Quote in the paperSubstantial claim - Interpretationreasoning
Risk and protective factors are inefficient, individually or in combinations, for predicting outcomes for any individual.
“It is insufficient because they are so inefficient, either individually or in combinations, for predicting outcomes for any individual.”
Quote in the paperNot a substantial claim - Premisecitation
The CDC has identified promotion and strengthening of connectedness at personal, family, and community levels as a key strategy for preventing suicidal behavior at all ages.
“the Centers for Disease Control has identified as a key strategy for preventing suicidal behavior at all ages “the promotion and strengthening of connectedness at personal, family, and community levels” (39).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [39] Centers for Disease Control and Prevention
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- Premisecitation
Connections to other individuals and to one's community may protect older persons against developing suicidal desire in the face of stressful life circumstances.
“connections to other individuals and to his or her community may serve to protect the older person against the development of suicidal desire in the face of stressful life circumstances.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [43] Van Orden, 2010, The interpersonal theory of suicide, Psychol Rev source
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- Premisecitation
In the presence of an acquired capability for suicide, painful psychological states of thwarted belongingness and perceived burdensomeness may become lethal.
“In the presence of an acquired capability for suicide (e.g., prior experience with pain or well developed cognitive models of one's death) these painful psychological states may become lethal.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [43] Van Orden, 2010, The interpersonal theory of suicide, Psychol Rev source
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- Premisecitation
The Interpersonal Theory proposes that family discord and functional impairments are associated with late life suicide because both factors likely engender perceptions of burdensomeness on others.
“The theory proposes that both family discord and functional impairments are associated with late life suicide because both factors are likely to engender perceptions of burdensomeness on others.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [43] Van Orden, 2010, The interpersonal theory of suicide, Psychol Rev source
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- Interpretationreasoning
This public health premise may apply more directly to older adults than to younger age groups because suicidal behavior in elders is much more lethal.
“This premise may apply more directly to older adults than younger age groups because suicidal behavior in elders is so much more lethal.”
Quote in the paperSubstantial claim - Premisecitation
Numerous reports from mixed-age and younger adult samples show associations between suicidal behavior and a range of neurobiological parameters.
“Numerous reports of associations between suicidal behavior and a range of neurobiological parameters have emerged from studies of mixed age and younger adult samples (52).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [52] Mann, 1999, Toward a clinical model of suicidal behavior in psychiatric patients, Am J Psychiatry source
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- Interpretationnone given
Risk factors in psychiatric, physical and functional, and social domains operate in complex interactions against a background of culture, personality traits, and neurobiological makeup.
“Risk factors in psychiatric, physical and functional, and social domains operate in complex interactions against a background colored by one's culture, personality traits, and even neurobiological make up.”
Quote in the paperNot a substantial claim - Premisecitation
Estimates suggest that as many as 200 young adults attempt suicide for every one who dies by suicide.
“Studies estimate that as many as 200 young adults attempt suicide for each one that dies by his own hand (55).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [55] Fremouw, 1990
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- Premisecitation
The Big Five personality traits of low Openness to Experience and high Neuroticism distinguished suicides from controls in another study.
“while in another, the “Big Five” personality traits of low Openness to Experience (OTE) and high Neuroticism (49) distinguished the groups (50).”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [49] Costa, 1992
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- cites [50] Duberstein, 1995, Openness to experience and completed suicide across the second half of life, Int Psychogeriatr source
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- Premisecitation
Older adults are reluctant to seek care in mental health clinics or providers' offices.
“Because older adults are reluctant to seek care in mental health clinics or providers' offices, however, interventions delivered in primary care are likely to be more effective (59).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [59] Bartels, 2004, Improving access to geriatric mental health services: a randomized trial comparing treatment engagement with integrated versus enhanced referral care for depression, anxiety, and at-risk alcohol use, Am J Psychiatry source
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- Interpretationcitation
Results of Oyama's meta-analysis cast additional doubt on whether primary care intervention alone will be sufficient, at least for elderly men.
“Results of Oyama's meta-analysis cast additional doubt on whether primary care intervention alone will be sufficient, at least for elderly men, who are by far the highest risk group in the U.S.”
Quote in the paperSubstantial claim- Rests on an assumption: Elderly men are by far the highest risk group for suicide in the U.S.
- Premisecitation
The Telehelp/Telecheck service is a rare example of selective prevention targeting completed suicide in older adults.
“The Telehelp/Telecheck service reported by DeLeo and colleagues represents a rare example of selective prevention in which completed suicide in older adults was the targeted outcome (65).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [65] De Leo, 2002, Suicide among the elderly: the long-term impact of a telephone support and assessment intervention in northern Italy, Br J Psychiatry source
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- Rests on an assumption: Examples of selective preventive interventions for suicide are rare.
- Premisecitation
Further analyses found that the effect was only significant for women.
“Further analyses found the effect was only significant for women, possibly because of the small numbers of men enrolled in the program and/or their resistance to a social outreach intervention of this nature.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [65] De Leo, 2002, Suicide among the elderly: the long-term impact of a telephone support and assessment intervention in northern Italy, Br J Psychiatry source
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- Interpretationcitation
Older men proved relatively more resistant to the effects of preventive intervention.
“Again, older men proved relatively more resistant to the effects of preventive intervention.”
Quote in the paperSubstantial claim - Premisecitation
In the United Kingdom, after legislation limited the pack size of over-the-counter paracetamol and salicylates, morbidity and mortality from overdose with those medications decreased significantly.
“Hawton and colleagues reported that after legislation was implemented to limited the pack size of paracetamol and salicylates sold over the counter in the United Kingdom, morbidity and mortality from overdose with those medications decreased significantly (66).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [66] Hawton, 2001, Effects of legislation restricting pack sizes of paracetamol and salicylate on self poisoning in the United Kingdom: before and after study, BMJ source
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- Premisecitation
In the United States, after the Brady Handgun Violence Prevention Act, there was a significantly greater reduction in handgun suicides among people over age 55 in states that newly implemented background checks and waiting periods than in states without such changes.
“Ludwig and Cooke observed that in the years following implementation of the legislation there was a significantly greater reduction suicides with a handgun by people over the age of 55 years in those states that newly implemented background checks and waiting periods for gun purchase than states in which no changes in procedures were necessary (67).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [67] Ludwig, 2000, Homicide and suicide rates associated with implementation of the Brady Handgun Violence Prevention Act, JAMA source
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- Interpretationreasoning
The most effective prevention program for suicide in later life likely incorporates elements of universal, selective, and indicated prevention.
“Because universal, selective, and indicated prevention target the suicidal process at different levels, it is likely that the most effective prevention program for suicide in later life would be one that incorporates elements of each.”
Quote in the paperSubstantial claim - Premisecitation
In that analysis, the relative risk for suicidal ideation or behavior during antidepressant treatment was significantly reduced for participants over age 65 who received antidepressants.
“They found that the relative risk for suicidal ideation or behavior emerging during antidepressant treatment was indeed elevated for participants under age 25, no different than placebo for those aged 25 – 64, and significantly reduced for those over age 65 who received antidepressant treatment.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [60] Stone, 2009, Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration, BMJ source
Not checked in the free run.
- Interpretationreasoning
Collaborative care delivered by primary care providers informed by mental health expertise has shown promise as an indicated preventive intervention.
“Collaborative care delivered by primary care providers informed by mental health expertise has shown promise as an indicated preventive intervention, although its effect in reducing suicide among elderly men remains to be determined.”
Quote in the paperSubstantial claim- Rests on an assumption: Affective illness often goes undetected and inadequately treated in primary care settings.
- Premisecitation
In that same analysis, the relative risk for suicidal ideation or behavior during antidepressant treatment was no different from placebo for participants aged 25 to 64.
“They found that the relative risk for suicidal ideation or behavior emerging during antidepressant treatment was indeed elevated for participants under age 25, no different than placebo for those aged 25 – 64, and significantly reduced for those over age 65 who received antidepressant treatment.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [60] Stone, 2009, Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration, BMJ source
Not checked in the free run.
- Study design and conductcitation
Neither trial could assess the effectiveness of the intervention on suicidal behavior because of sample size limitations.
“Due to sample size limitations, neither trial could assess the effectiveness of the intervention on suicidal behavior, however”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [63] Alexopoulos, 2009, Reducing suicidal ideation and depression in older primary care patients: 24-month outcomes of the PROSPECT study, Am J Psychiatry source
Not checked in the free run.
- cites [64] Unutzer, 2006, Reducing suicidal ideation in depressed older primary care patients, J Am Geriatr Soc source
Not checked in the free run.
- Premisecitation
During the Telehelp/Telecheck service's 11 years of operation, there were significantly fewer suicides among its clients than anticipated in the elder population of that region.
“During the service's 11 year in operation there were significantly fewer suicides among its clients than were anticipated in the elder population of that region.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [65] De Leo, 2002, Suicide among the elderly: the long-term impact of a telephone support and assessment intervention in northern Italy, Br J Psychiatry source
Not checked in the free run.
- Interpretationcitation
Interventions delivered in primary care are likely to be more effective for older adults.
“Because older adults are reluctant to seek care in mental health clinics or providers' offices, however, interventions delivered in primary care are likely to be more effective (59).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [59] Bartels, 2004, Improving access to geriatric mental health services: a randomized trial comparing treatment engagement with integrated versus enhanced referral care for depression, anxiety, and at-risk alcohol use, Am J Psychiatry source
Not checked in the free run.
- Interpretationcitation
Ecological studies and natural experiments offer some support for the effectiveness of universal prevention in later life.
“Although there are no randomized controlled trials of universal prevention of suicide, ecological studies and “natural experiments” offer some support for their effectiveness in later life.”
Quote in the paperSubstantial claim- Rests on an assumption: There are no randomized controlled trials of universal prevention of suicide.
- Premisecitation
Two randomized trials found significantly greater reductions in depressive symptoms and suicidal ideation among depressed older primary care patients who received collaborative stepped-care interventions compared with care-as-usual.
“both studies found significantly greater reductions in depressive symptoms and suicidal ideation in depressed older adults who received the experimental interventions (63, 64).”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [63] Alexopoulos, 2009, Reducing suicidal ideation and depression in older primary care patients: 24-month outcomes of the PROSPECT study, Am J Psychiatry source
Not checked in the free run.
- cites [64] Unutzer, 2006, Reducing suicidal ideation in depressed older primary care patients, J Am Geriatr Soc source
Not checked in the free run.
- Premisecitation
In an analysis of 372 double-blind randomized placebo-controlled antidepressant trials, the relative risk for suicidal ideation or behavior during treatment was elevated for participants under age 25.
“They found that the relative risk for suicidal ideation or behavior emerging during antidepressant treatment was indeed elevated for participants under age 25, no different than placebo for those aged 25 – 64, and significantly reduced for those over age 65 who received antidepressant treatment.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [60] Stone, 2009, Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration, BMJ source
Not checked in the free run.
- May combine two claims. 24
- Classified as probably not a substantial claim. 14
May combine two claims.
Findingnone givenSince 1986, US older adult suicide rates dropped by over 35 percent, while rates among ages 35 to 64 rose by almost 20 percent over the last 8 years.
“since 1986 rates have dropped among older adults in the United States by over 35 percent, even as suicide rates have risen by almost 20 percent over the last 8 years among those ages 35 to 64.”
Quote in the paperNot a substantial claimMay combine two claims.
FindingcitationThe overall US suicide rate fell slowly but steadily from 1985 through 2000, after which it began to rise marginally.
“the overall rate of suicide fell slowly but steadily from 1985 through 2000, after which it has begun to rise again marginally (1).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [1] Centers for Disease Control and Prevention
Not checked in the free run.
May combine two claims.
FindingcitationWhite men have higher suicide rates at every point in the life course, peaking in the oldest age group at over 45 per 100,000 per year, over four times the overall age-adjusted US rate of 11.5 per 100,000 per year.
“Most striking is the higher rate at every point in the life course for white men, rising to a peak in the oldest age group of over 45 per 100,000 per year, over 4 times the nation's overall age adjusted rate of 11.5 per 100,000 per year (1).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [1] Centers for Disease Control and Prevention
Not checked in the free run.
May combine two claims.
PremisecitationIn most countries that report suicide statistics to the World Health Organization, suicide rates rise with age for both men and women and peak in old, old age.
“In most countries throughout the world that report such statistics to the World Health Organization, suicide rates tend to rise as a function of age for both men and women to a peak in old, old age (2).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [2] World Health Organization—Mental Health
Not checked in the free run.
May combine two claims.
InterpretationreasoningAs the baby boom cohort enters older adulthood in large numbers, suicide rates in men and women are anticipated to rise again, producing substantial increases in the absolute numbers of older adult suicides.
“we anticipate that the rate of suicide in men and women will rise again, resulting in substantial increases in the absolute numbers of senior citizens dying by their own hands.”
Quote in the paperSubstantial claim- Rests on an assumption: Birth cohorts carry a characteristic propensity to suicide as they age.
- Rests on an assumption: The baby boom cohort has had relatively higher suicide rates at any given age than earlier or subsequent birth cohorts.
Classified as probably not a substantial claim.
Interpretationnone givenIt remains unclear how applicable lessons from suicidal ideation and attempts in later life are to completed suicide.
“It remains unclear how applicable lessons learned from the study of suicidal ideation and attempts in later life are to the understanding of completed suicide.”
Quote in the paperSubstantial claimMay combine two claims.
Premisenone givenThe leading edge of the baby boom cohort will reach age 65 in 2011, fueling rapid growth over the next 20 years in the older adult population.
“As well, the leading edge of the baby boom cohort will reach age 65 in 2011, fueling rapid growth over the next 20 years in the total size of the older adult population.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationSerious relationship and financial problems distinguished older adult suicides and near fatal suicide attempters from controls in New Zealand, findings replicated in Sweden.
“Serious relationship and financial problems distinguished older adult suicides and near fatal suicide attempters from controls in New Zealand (20), findings replicated by Rubenowitz and colleagues in Sweden (16).”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [20] Beautrais, 2002, A case–control study of suicide and attempted suicide in older adults, Suicide Life Threat Behav source
Not checked in the free run.
- cites [16] Rubenowitz, 2001, Life events and psychosocial factors in elderly suicides—a case–control study, Psychol Med source
Not checked in the free run.
May combine two claims.
PremisecitationHarwood and colleagues compared completed suicides with controls who died of natural causes in hospital, whereas other listed studies used living community controls.
“Harwood and colleagues compared completed suicides with controls who died of natural causes in hospital (12), whereas the other listed studies used living community controls.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [12] Harwood, 2001, Psychiatric disorder and personality factors associated with suicide in older people: a descriptive and case–control study, Int J Geriatr Psychiatry source
Not checked in the free run.
May combine two claims.
PremisereasoningSpecific factors in psychiatric illness, social connectedness, physical illness, and functional capacity appear to influence suicide risk in older adults.
“Results indicate that specific factors in domains of psychiatric illness, social connectedness of the older person with his or her family, friends, and community, physical illness and functional capacity appear to influence risk for suicide.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenThe cognitive mechanisms underlying relationships between cognitive control, problem solving, and suicidal behavior remain obscure.
“The cognitive mechanisms underlying relationships between cognitive control, problem solving, and suicidal behavior remain obscure.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationPatients with three physical illnesses had approximately a threefold increase in estimated relative risk for suicide compared with those with no diagnosis, and those with seven or more illnesses had approximately nine times greater risk.
“They found that patients with three physical illnesses had approximately a threefold increase in estimated relative risk for suicide compared with subjects who had no diagnosis, whereas older adults who had seven or more illnesses had approximately nine times greater risk for suicide.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [26] Juurlink, 2004, Medical illness and the risk of suicide in the elderly, Arch Intern Med source
Not checked in the free run.
May combine two claims.
Premiseown dataPsychiatric illness is present in 71% to 97% of older adult suicides, with affective disorder being the most common.
“Psychiatric illness is present in from 71% to 97% of suicides, with affective disorder being the most common.”
Quote in the paperSubstantial claimMay combine two claims.
Premiseown dataThe highest odds ratios for suicide in older adults were observed for mood disorders, with lower and more mixed results for substance abuse and dependence, schizophrenia, and anxiety disorders.
“The highest ORs were observed for mood disorders, with lower ORs and generally more mixed results in those studies that examined substance abuse and dependence, schizophrenia, anxiety disorders.”
Quote in the paperSubstantial claimMay combine two claims.
PremisecitationLi and Conwell found that men with severe and uncontrolled pain were at especially high risk for self injury ideation, whereas no such association was observed in women.
“Li and Conwell found that men with severe and uncontrolled pain were at especially high risk for self injury ideation, whereas no such association was observed in women (31).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [31] Li, 2010, Pain and self-injury ideation in elderly men and women receiving home care, J Am Geriatr Soc source
Not checked in the free run.
May combine two claims.
PremisecitationKeilp and colleagues found that adult suicide attempters performed poorly on frontal executive tasks relative to controls, similar to King and colleagues' observation in older adult attempters.
“Keilp and colleagues found that adult suicide attempters performed poorly on frontal executive tasks relative to controls (33), a similar observation to one made by King and colleagues in older adult attempters (34).”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [33] Keilp, 2001, Neuropsychological dysfunction in depressed suicide attempters, Am J Psychiatry source
Not checked in the free run.
- cites [34] King, 2000, A neuropsychological comparison of depressed suicide attempters and nonattempters, J Neuropsychiatry Clin Neurosci source
Not checked in the free run.
May combine two claims.
InterpretationcitationDombrovski and colleagues' finding of deficits in depressed attempters supports the notion that late life suicidal behavior is in some instances associated with impaired decision-making based on impaired ability to access and use prior experience, which may relate to underlying age-related ventral prefrontal pathology.
“Their finding of deficits in depressed attempters supports the notion that late life suicidal behavior is in some instances associated with impaired decision-making based on impaired ability to access and use prior experience, which in turn may be related to underlying age-related ventral prefrontal pathology (36).”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [36] Arango, 1997, Postmortem findings in suicide victims. Implications for in vivo imaging studies, Ann N Y Acad Sci source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationHarwood and colleagues reported that dementia or delirium was significantly less common in suicides than controls.
“Harwood et al reported, for example, that the diagnosis of dementia or delirium was significantly less common in suicides than controls”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [12] Harwood, 2001, Psychiatric disorder and personality factors associated with suicide in older people: a descriptive and case–control study, Int J Geriatr Psychiatry source
Not checked in the free run.
Probably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenIn the struggle with acute and chronic medical illnesses and functional decline, some older persons become socially disconnected.
“In the struggle with acute and chronic medical illnesses and functional decline, some become socially disconnected.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenRelative suicide risk increases among those who are less resilient and develop early symptoms of psychiatric illness.
“Relative risk increases among those who are less resilient and develop early symptoms of psychiatric illness.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationSpirituality and religiousness have been cited as protective factors against the development of depression and suicidality, a relationship that might be understood as a function of connectedness at a spiritual or instrumental level.
“Spirituality and religiousness have been cited as protective factors against the development of the depression and suicidality (19, 45), a relationship that might also be understood as a function of connectedness at a spiritual or instrumental level”
Quote in the paperNot a substantial claim0 of 2 sources checkedProbably not a substantial claim: may not pass S3 (load-bearing).
InterpretationcitationDifferences in suicide risk by gender and race/ethnicity with aging might be understood in part by stronger ties to supportive others that women and some minority communities have capacity to establish relative to men and white race groups in general.
“differences in suicide risk as a function of gender and race/ethnicity with aging might be understood in part by the stronger ties to supportive others that woman and some minority communities have capacity to establish relative to men and white race groups in general (46).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [46] Goldsmith, 2002
Not checked in the free run.
Classified as probably not a substantial claim. May combine two claims.
PremisecitationThe Interpersonal Theory of Suicide proposes that thwarted belongingness and perceived burdensomeness are two proximal causes of the desire for suicide, with a particularly dangerous level of suicidal desire resulting from their simultaneous presence.
“It proposes that there are two proximal causes of the desire for suicide -- thwarted belongingness and perceived burdensomeness -- with a particularly dangerous level of suicidal desire resulting from the simultaneous presence of both factors.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [43] Van Orden, 2010, The interpersonal theory of suicide, Psychol Rev source
Not checked in the free run.
May combine two claims.
InterpretationreasoningKnowledge of factors that increase or decrease suicide risk in older adults is necessary but not sufficient for effective design of preventive interventions.
“Knowledge of factors that increase or decrease risk for suicide in older adults is necessary but not sufficient for the effective design of preventive interventions.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationPsychological autopsy studies have shown that older adult suicides were significantly less likely to have had a confidante, more likely to live alone, and less likely to participate in community activities, be active in organizations, or have a hobby.
“PA studies have shown that older adult suicides were significantly less likely to have had a confidante (41), more likely to live alone than their peers in the community (7), and less likely to participate in community activities (19), be active in organizations, or have a hobby (16).”
Quote in the paperSubstantial claim0 of 3 sources checked- cites [41] Miller, 1977, A psychological autopsy of a geriatric suicide, J Geriatr Psychiatry
Not checked in the free run.
- cites [7] Barraclough, 1971, Suicide in the elderly: recent developments in psychogeriatrics, Br J Psychiatry
Not checked in the free run.
- cites [19] Duberstein, 2004, Poor social integration and suicide: fact or artifact? A case–control study, Psychol Med source
Not checked in the free run.
May combine two claims.
PremisecitationSuicidal elders have been characterized as timid and seclusive, hostile, rigid, and with an independent style.
“Suicidal elders have been characterized as timid and seclusive (47), hostile, rigid and with an independent style (47, 48).”
Quote in the paperNot a substantial claim0 of 2 sources checkedProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThe Interpersonal Theory proposes that risk factors for suicide, including psychiatric illness, elevate risk by causing or exacerbating thwarted belongingness, perceived burdensomeness, and/or acquired capability.
“The Interpersonal Theory proposes that risk factors for suicide, including psychiatric illness, elevate risk for suicide by causing or exacerbating thwarted belongingness, perceived burdensomeness and/or acquired capability.”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [43] Van Orden, 2010, The interpersonal theory of suicide, Psychol Rev source
Not checked in the free run.
Probably not a substantial claim: may not pass S1 (asserted), S3 (load-bearing). May combine two claims.
PremisecitationDuberstein and colleagues hypothesize that older adults low in Openness to Experience are at risk for suicide because they are less well equipped socially and psychologically to manage aging, and less likely to be recognized as distressed and needing intervention.
“Duberstein and colleagues hypothesize that older adults low in OTE are at risk for suicide because they are less well equipped socially and psychologically to manage the challenges of aging, and less likely to be recognized as being in distress and need of intervention (51)”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [51] Duberstein, 2001, Are closed-minded people more open to the idea of killing themselves?, Suicide Life Threat Behav source
Not checked in the free run.
May combine two claims.
InterpretationreasoningWidespread use of risk and protective factors would produce many false positives leading to unnecessary, intrusive, expensive interventions, and many false negatives leaving at-risk elders undetected.
“The large number of “false positives” that resulted from their widespread use would lead to unnecessary, intrusive, and expensive interventions for those who did not need them, while many “false negatives” results would leave at-risk elders undetected and unprotected.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim. May combine two claims.
InterpretationreasoningSome older adults become more frankly depressed and hopeless, and the most vulnerable enter the peri-suicidal state.
“Some become more frankly depressed and hopeless, the most vulnerable of whom enter the peri-suicidal”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing), S4 (based).
Interpretationnone givenOn a foundation of personality characteristics, neurobiological factors, and cultural context, each older person encounters stressful events.
“On a foundation of personality characteristics, individual neurobiological factors, and cultural context, each older person encounters stressful events.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningInterventions to prevent the development of the suicidal state are especially critical in older adults.
“the implications are clear: interventions to prevent the development of the suicidal state are especially critical in this age group.”
Quote in the paperNot a substantial claim- Rests on an assumption: Suicidal processes unfold over time, with risks accumulating through progressively more proximal risk factors and/or loss of protective buffers.
May combine two claims.
PremisecitationIn Oyama's meta-analysis of five quasi-experimental studies in Japanese rural regions with high suicide rates (greater than 160 per 100,000), overall risk was significantly reduced in men and women when follow-up was conducted by a psychiatrist, but only in women when follow-up was conducted by general practitioners.
“Overall, risk was significantly reduced in men and women when follow-up was conducted by a psychiatrist, but only in women when follow-up was conducted by general practitioners.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [68] Oyama, 2008, Effect of community-based intervention using depression screening on elderly suicide risk: a meta-analysis of the evidence from Japan, Community Ment Health J source
Not checked in the free run.
Classified as probably not a substantial claim.
Study design and conductreasoningThe high proportions of female subjects in these trials leave open the question of how effective the interventions would be in reducing attempted and completed suicide among men, the group at greatest risk in later life.
“the relatively high proportions of female subjects leaves open the question of how effective they would be in reducing attempted and completed suicide among those at greatest risk in later life, men.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
Study design and conductreasoningThe effect of collaborative care in reducing suicide among elderly men remains to be determined.
“Collaborative care delivered by primary care providers informed by mental health expertise has shown promise as an indicated preventive intervention, although its effect in reducing suicide among elderly men remains to be determined.”
Quote in the paperSubstantial claim
The paper relies on this without support.
Birth cohorts carry a characteristic propensity to suicide as they age.
“Birth cohorts tend to carry with them a characteristic propensity to suicide as they age.”
The paper relies on this without support.
The baby boom cohort has had relatively higher suicide rates at any given age than earlier or subsequent birth cohorts.
“The “baby boom” cohort, those born between 1946 and 1964, has had relatively higher suicide rates at any given age than earlier or subsequent birth cohorts.”
The paper relies on this without support.
Risk states are dynamic and wax and wane over short periods of time.
“risk states are dynamic -- they wax and wane over short periods of time.”
The paper relies on this without support.
Identification of risk and protective factors can guide prevention efforts.
“identification of risk and protective factors can guide our prevention efforts.”
The paper relies on this without support.
Affective illness often goes undetected and inadequately treated in primary care settings.
“However, affective illness often goes undetected and inadequately treated in primary care settings.”
The paper relies on this without support.
The baby boom cohort has carried a greater propensity to suicide than earlier or later birth cohorts.
“fueled by aging of the baby boom cohort that life-long has carried a greater propensity to suicide than earlier or later birth cohorts”
The paper relies on this without support.
Depression is an important pathogenetic factor in late-life suicide.
“The importance of depression as a pathogenetic factor in late life suicide makes its detection and effective treatment of paramount importance.”
The paper relies on this without support.
Elderly men are by far the highest risk group for suicide in the U.S.
“who are by far the highest risk group in the U.S.”
The paper relies on this without support.
The older adult population is anticipated to increase rapidly.
“Anticipated rapid increases in the size of the older adult population”
The paper relies on this without support.
There are no randomized controlled trials of universal prevention of suicide.
“Although there are no randomized controlled trials of universal prevention of suicide”
The paper relies on this without support.
Examples of selective preventive interventions for suicide are rare.
“Examples of selective preventive interventions for suicide are rare”
The paper relies on this without support.
Suicidal processes unfold over time, with risks accumulating through progressively more proximal risk factors and/or loss of protective buffers.
“Risks mount over time with the accumulation of progressively more proximal risk factors and/or the loss of protective buffers.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Older men are at particularly elevated risk in countries with high rates of older adult suicide.
“Older men are at particularly elevated risk in these countries [1,2]”
From A systematic review of social factors and suicidal behavior in older adulthood (2012) · cites this paper as [2]
In many countries older adult suicidal behavior is highly lethal.
“in many countries older adult suicidal behavior is highly lethal [2]”
From A systematic review of social factors and suicidal behavior in older adulthood (2012) · cites this paper as [2]
Psychological autopsy studies indicate mental disorder is present in 71-97% of older adults who die by suicide, with depression as the most common diagnosis.
“mental disorder is present in 71–97% of older adults who die by suicide with depression as the most common diagnosis [2]”
From A systematic review of social factors and suicidal behavior in older adulthood (2012) · cites this paper as [2]
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Medical illness and the risk of suicide in the elderly
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The Interpersonal Theory of Suicide Applied to Male Prisoners
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Exergames and Depressive Symptoms in Older Adults: A Systematic Review
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Risk of Suicide Among Patients With Parkinson Disease
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Firearm Suicides in the Elderly: A Narrative Review and Call for Action
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Prevalence and correlates of depression among older urban community‐dwelling adults in Sri Lanka
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Suicidality in the geriatric population
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Shards of sorrow: Older men's accounts of their depression experience
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Path analysis of suicide ideation in older people
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- Authors
- Conwell, Y., Van Orden, K., & Caine, E. D.
- Affiliations
- University of Rochester Medicine (US)
- Corresponding author
- Conwell, Yeates
- Venue
- Psychiatric Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2011-06
- Volume
- 34
- Issue
- 2
- Pages
- 451-468
- ISSN
- 0193-953X (ISSN-L)
- PMC
- PMC3107573
- OpenAlex
- W2087539512
- Semantic Scholar
- 7cb87465569ae52771b5f449fa4313e9bfe8818f
- Cited by
- 555
- References
- 67
- Citations by year
- 2026: 25 · 2025: 33 · 2024: 41 · 2023: 32 · 2022: 40 · 2021: 52 · 2020: 83 · 2019: 42 · 2018: 33 · 2017: 42 · 2016: 27 · 2015: 36 · 2014: 35 · 2013: 23 · 2012: 8
- FWCI
- 3.23
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychiatric Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (5t32mh020061-25)
- National Institute of Mental Health (T32 MH20061, T32-MH020061)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Social Sciences › Sociology and Political Science › Homicide, Infanticide, and Child Abuse
- Social Sciences › Psychology › Clinical Psychology › Grief, Bereavement, and Mental Health
- Keywords
- suicide, older adults, late-life suicide, suicide risk factors, suicide prevention, suicide prevention interventions, community response
- MeSH terms
- Suicide Prevention, Aged, Aging, Humans, Prognosis, Risk Factors, Social Support, Stress, Psychological, Suicide, Comorbidity
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-06.
Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-06.
Statistics and arithmetic are recomputed, not judged.
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