Toward prevention of bipolar disorder in at-risk children: Potential strategies ahead of the data
Open accessAbstract
BACKGROUND: Despite the well-documented negative impact of untreated bipolar illness, approaches to early intervention in childhood-onset bipolar and related disorders are not well delineated. METHODS: We reviewed the extant treatment literature on children at high risk for bipolar disorder, with definitions based on family history, childhood adversity, and prodromal symptoms. RESULTS: A panoply of approaches have been described, but most interventions are based on an inadequate database to support their routine implementation. We classify early stage interventions as a function of their safety and tolerability with the hope that these might generate more rigorous study and a stronger database. LIMITATIONS: Critics may rightly argue that identifying viable treatment methods is premature given our lack of ability to reliably predict illness trajectory in very young children. However, many of the psychosocial and pharmacological interventions we present could have nonspecific positive effects across a variety of symptoms, syndromes, and diagnoses, further enhancing the rationale for more rigorous study. CONCLUSIONS: Early stage interventions have the potential to improve functioning in prodromal illness and exert long-term positive effects on the course of illness. Many of the safest interventions deserve consideration for implementation and dissemination studies.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Indicated prevention in bipolar disorder was developed only fifteen years ago and is rapidly emerging, but its supporting evidence lags behind that for CHR-P.
“Indicated prevention in bipolar disorder was developed, following the CHR-P template, only fifteen years ago 96,97 , and is rapidly emerging 98-101 . The supporting evidence lags behind that for CHR-P 99,102 .”
From Preventive psychiatry: a blueprint for improving the mental health of young people (2021) · cites this paper as [102]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Merikangas, K. R., He, J.-P., Burstein, M., Swanson, S. A., Avenevoli, S., Cui, L., Benjet, C., Georgiades, K., & Swendsen, J. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2010.05.017 · Cited by 6,278 · see citing works
The Lifelong Effects of Early Childhood Adversity and Toxic Stress
Shonkoff, J. P., Garner, A. S., THE COMMITTEE ON PSYCHOSOCIAL ASPECTS OF CHILD AND FAMILY HEALTH, C. O. E. C., Siegel, B. S., Dobbins, M. I., Earls, M. F., Garner, A. S., McGuinn, L., Pascoe, J., & Wood, D. L. (2012) · Pediatrics · doi:10.1542/peds.2011-2663 · Cited by 5,164 · cited 1× · see citing works
“Such a study should have a very high priority given the multiplicity of difficult medical and psychiatric illness associated with toxic stress in childhood (Shonkoff and Garner, 2012).”
BackgroundAccelerated telomere shortening in response to life stress
Epel, E. S., Blackburn, E. H., Lin, J., Dhabhar, F. S., Adler, N. E., Morrow, J. D., & Cawthon, R. M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407162101 · Cited by 3,002 · see citing works
Manuscripts Accepted for Publication
(2005) · Child Development · doi:10.1111/j.1467-8624.2005.00876.x · Cited by 2,051 · see citing works
The NIMH Research Domain Criteria (RDoC) Project: Precision Medicine for Psychiatry
Insel, T. R. (2014) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2014.14020138 · Cited by 1,472 · see citing works
Olds, D., Henderson, Jr., Cole, R., Eckenrode, J., Kitzman, H., Luckey, D., Pettitt, L., Sidora, K., Morris, P., & Powers, J. (1998) · JAMA · doi:10.1001/jama.280.14.1238 · Cited by 1,122 · see citing works
Spearing, M. K., Post, R. M., Leverich, G. S., Brandt, D., & Nolen, W. (1997) · Psychiatry Research · doi:10.1016/s0165-1781(97)00123-6 · Cited by 978 · see citing works
Self-citationGalletly, C., Castle, D., Dark, F., Humberstone, V., Jablensky, A., Killackey, E., Kulkarni, J., McGorry, P., Nielssen, O., & Tran, N. (2016) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867416641195 · Cited by 877 · cited 1× · see citing works
“Most of these criticisms have been addressed and overcome in successful efforts to study effective approaches and develop national programs for early recognition and treatment (Galletly et al., 2016; Lieberman et al., 2019).”
BackgroundPerlis, R. H., Miyahara, S., Marangell, L. B., Wisniewski, S. R., Ostacher, M., DelBello, M. P., Bowden, C. L., Sachs, G. S., & Nierenberg, A. A. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.01.022 · Cited by 852 · see citing works
Self-citationFamily Management in the Prevention of Morbidity of Schizophrenia
Falloon, I. R. H. (1985) · Archives of General Psychiatry · doi:10.1001/archpsyc.1985.01790320059008 · Cited by 587 · see citing works
Birmaher, B., Axelson, D., Goldstein, B., Strober, M., Gill, Hunt, J., Houck, P., Ha, W., Iyengar, S., Kim, E., et al. (2009) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.08101569 · Cited by 524 · see citing works
Self-citationA Placebo-Controlled Study of Lamotrigine and Gabapentin Monotherapy in Refractory Mood Disorders
Frye, M. A., Ketter, T. A., Kimbrell, T. A., Dunn, R. T., Speer, A. M., Osuch, E. A., Luckenbaugh, D. A., Corá-Locatelli, G., Leverich, G. S., & Post, R. M. (2000) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-200012000-00004 · Cited by 446 · see citing works
Self-citationThe promise of N-acetylcysteine in neuropsychiatry
Berk, M., Malhi, G. S., Gray, L. J., & Dean, O. M. (2013) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2013.01.001 · Cited by 434 · cited 2× · see citing works
“N-acetylcysteine has positive data in bipolar depression in adults and in multiple common comorbidities of bipolar disorder including substance abuse (Berk et al., 2013).”
BackgroundEarly-Onset Bipolar Disorder and Treatment Delay Are Risk Factors for Poor Outcome in Adulthood
Post, R. M., Leverich, G. S., Kupka, R. W., Keck, P. E., McElroy, S. L., Altshuler, L. L., Frye, M. A., Luckenbaugh, D. A., Rowe, M., Grunze, H., et al. (2010) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08m04994yel · Cited by 360 · see citing works
Self-citationBirmaher, B., Axelson, D., Monk, K., Kalas, C., Goldstein, B., Hickey, M. B., Obreja, M., Ehmann, M., Iyengar, S., Shamseddeen, W., et al. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2008.546 · Cited by 360 · see citing works
Self-citationMeta-Analysis of Epidemiologic Studies of Pediatric Bipolar Disorder
Meter, A. V., Moreira, A. L. R., & Youngstrom, E. A. (2011) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.10m06290 · Cited by 352 · see citing works
The role of childhood trauma in bipolar disorders
Aas, M., Henry, C., Andreassen, O. A., Bellivier, F., Melle, I. S., & Étain, B. (2016) · International Journal of Bipolar Disorders · doi:10.1186/s40345-015-0042-0 · Cited by 345 · see citing works
Poston, L., Harthoorn, L. F., & van der Beek, E. M. (2010) · Pediatric Research · doi:10.1203/pdr.0b013e3182055ede · Cited by 283 · see citing works
Geller, B. (2012) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2011.1508 · Cited by 281 · see citing works
Bipolar Disorder at Prospective Follow-Up of Adults Who Had Prepubertal Major Depressive Disorder
Geller, B., Zimerman, B., Williams, M., Bolhofner, K., & Craney, J. L. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.1.125 · Cited by 270 · see citing works
Axelson, D., Goldstein, B. I., Goldstein, T. R., Monk, K., Yu, H., Hickey, M. B., Sakolsky, D. J., Diler, R. S., Hafeman, D., Merranko, J. A., et al. (2015) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2014.14010035 · Cited by 263 · see citing works
Self-citationMcGorry, P. D., Nelson, B., Markulev, C., Yuen, H. P., Schäfer, M. R., Mossaheb, N., Schlögelhofer, M., Smesny, S., Hickie, I. B., Berger, G. E., et al. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.2902 · Cited by 262 · see citing works
Wagner, K. D., Kowatch, R. A., Emslie, G. J., Findling, R. L., Wilens, T. E., McCague, K., D’Souza, J., Wamil, A., Lehman, R. B., Berv, D., et al. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.7.1179 · Cited by 259 · see citing works
Self-citationGoldstein, B. I., Birmaher, B. B., Carlson, G. A., DelBello, M. P., Findling, R. L., Fristad, M. A., Kowatch, R. A., Miklowitz, D. J., Nery, F. G., Algorta, G. P., et al. (2017) · Bipolar Disorders · doi:10.1111/bdi.12556 · Cited by 245 · see citing works
Self-citationEfficacy and Safety of Lamotrigine as Add-On Treatment to Lithium in Bipolar Depression
van der Loos, M. L. M., Mulder, P. G. H., Hartong, E. G. T. M., Blom, M. B. J., Vergouwen, A. C. M., de Keyzer, H. J. U. E. M., Notten, P., Luteijn, M. L., Timmermans, M. A. Y., Vieta, E., et al. (2008) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.08m04152 · Cited by 243 · see citing works
Family‐Focused Therapy for Bipolar Disorder: Reflections on 30 Years of Research
Miklowitz, D. J., & Chung, B. (2016) · Family Process · doi:10.1111/famp.12237 · Cited by 243 · see citing works
Self-citationKeck, P. E., Mintz, J., McElroy, S. L., Freeman, M. P., Suppes, T., Frye, M. A., Altshuler, L. L., Kupka, R., Nolen, W. A., Leverich, G. S., et al. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.056 · Cited by 234 · see citing works
Self-citationMiklowitz, D. J., Schneck, C. D., Singh, M. K., Taylor, D. O., George, E. L., Cosgrove, V. E., Howe, M. E., Dickinson, L. M., Garber, J., & Chang, K. (2013) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2012.10.007 · Cited by 220 · see citing works
Self-citationKessing, L. V., Hansen, H. V., Hvenegaard, A., Christensen, E. M., Dam, H., Gluud, C., Wetterslev, J., & The Early Intervention Affective Disorders (EIA) Trial Group (2013) · British Journal of Psychiatry · doi:10.1192/bjp.bp.112.113548 · Cited by 219 · see citing works
Staging in bipolar disorder: from theoretical framework to clinical utility
Berk, M., Post, R., Ratheesh, A., Gliddon, E., Singh, A., Vieta, E., Carvalho, A. F., Ashton, M. M., Berk, L., Cotton, S. M., et al. (2017) · World Psychiatry · doi:10.1002/wps.20441 · Cited by 216 · see citing works
Self-citationHafeman, D. M., Merranko, J., Axelson, D., Goldstein, B. I., Goldstein, T., Monk, K., Hickey, M. B., Sakolsky, D., Diler, R., Iyengar, S., et al. (2016) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2015.15040414 · Cited by 212 · see citing works
Self-citationWICKRAMARATNE, P. J., Gameroff, M. J., Pilowsky, D. J., Hughes, C. W., Garber, J., Malloy, E., King, C. A., Cerda, G., Sood, A. B., Alpert, J. E., et al. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.10010032 · Cited by 190 · see citing works
Hudziak, J. J., Albaugh, M. D., Ducharme, S., Karama, S., Spottswood, M., Crehan, E. T., Evans, A. C., & Botteron, K. N. (2014) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2014.06.015 · Cited by 189 · see citing works
Longer-term outcome in the prevention of psychotic disorders by the Vienna omega-3 study
Amminger, G. P., Schäfer, M. R., Schlögelhofer, M., Klier, C. M., & McGorry, P. D. (2015) · Nature Communications · doi:10.1038/ncomms8934 · Cited by 188 · see citing works
Casillas, K. L., Fauchier, A., Derkash, B. T., & Garrido, E. F. (2015) · Child Abuse & Neglect · doi:10.1016/j.chiabu.2015.10.009 · Cited by 184 · see citing works
Supplementation with Omega-3 Fatty Acids in Psychiatric Disorders: A Review of Literature Data
Bozzatello, P., Brignolo, E., Grandi, E. D., & Bellino, S. (2016) · Journal of Clinical Medicine · doi:10.3390/jcm5080067 · Cited by 180 · see citing works
A Pilot Controlled Trial of Topiramate for Mania in Children and Adolescents With Bipolar Disorder
DelBello, M. P., Findling, R. L., Kushner, S. F., Wang, D., Olson, W. H., Capece, J. A., Fazzio, L., & Rosenthal, N. R. (2005) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/01.chi.0000159151.75345.20 · Cited by 179 · see citing works
Self-citationRosenblat, J. D., & McIntyre, R. S. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.10.042 · Cited by 179 · see citing works
Combination Lithium and Divalproex Sodium in Pediatric Bipolarity
Findling, R. L., McNamara, N., Gracious, B., Youngstrom, E. A., Stansbrey, R. J., Reed, M. D., Demeter, C., BRANICKY, L. A., FISHER, K. E., & Calabrese, J. R. (2003) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/01.chi.0000046893.27264.53 · Cited by 174 · see citing works
Self-citationHafeman, D., Merranko, J. A., Goldstein, T. R., Axelson, D., Goldstein, B. I., Monk, K., Hickey, M. B., Sakolsky, D. J., Diler, R. S., Iyengar, S., et al. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.1763 · Cited by 173 · see citing works
Self-citationDelBello, M. P., Chang, K., Welge, J. A., Adler, C. M., Rana, M., Howe, M. E., Bryan, H., Vogel, D., Sampang, S. J., Delgado, S. V., et al. (2009) · Bipolar Disorders · doi:10.1111/j.1399-5618.2009.00728.x · Cited by 172 · see citing works
Self-citationThe potential use of biomarkers as an adjunctive tool for staging bipolar disorder
Kapczinski, F. P., Dias, V. V., Kauer‐Sant’Anna, M., Brietzke, E. M., Vázquez, G. H., Vieta, E., & Berk, M. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.07.027 · Cited by 167 · see citing works
Omega-3 fatty acid monotherapy for pediatric bipolar disorder: A prospective open-label trial
Wozniak, J. R., Biederman, J., Mick, E. O., Waxmonsky, J. G., Hantsoo, L. V., Best-Popescu, C. A., Cluette‐Brown, J. E., & Laposata, M. (2007) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2006.11.006 · Cited by 167 · see citing works
Parental Expressed Emotion and Youth Psychopathology: New Directions for an Old Construct
Peris, T. S., & Miklowitz, D. J. (2014) · Child Psychiatry & Human Development · doi:10.1007/s10578-014-0526-7 · Cited by 166 · see citing works
Self-citationOutpatient Visits and Medication Prescribing for US Children With Mental Health Conditions
Anderson, L. E., Chen, M. L., Perrin, J. M., & Cleave, J. M. V. (2015) · PEDIATRICS · doi:10.1542/peds.2015-0807 · Cited by 166 · see citing works
Facial Emotion Labeling Deficits in Children and Adolescents at Risk for Bipolar Disorder
Brotman, M. A., Guyer, A. E., Lawson, E. S., Horsey, S. E., Rich, B. A., Dickstein, D. P., Pine, D. S., & Leibenluft, E. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2007.06122050 · Cited by 164 · see citing works
Lithium in the Acute Treatment of Bipolar I Disorder: A Double-Blind, Placebo-Controlled Study
Findling, R. L., Robb, A. S., McNamara, N., Pavuluri, M. N., Kafantaris, V., Scheffer, R. E., Frazier, J. A., Rynn, M. A., DelBello, M. P., Kowatch, R. A., et al. (2015) · PEDIATRICS · doi:10.1542/peds.2015-0743 · Cited by 158 · see citing works
Self-citationEarly Detection and Preventive Intervention in Schizophrenia: From Fantasy to Reality
Lieberman, J. A., Small, S. A., & Girgis, R. R. (2019) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2019.19080865 · Cited by 158 · see citing works
Acetyl- <scp>l</scp> -carnitine deficiency in patients with major depressive disorder
Nasca, C., Bigio, B., Lee, F. S., Young, S. P., Kautz, M. M., Albright, A., Beasley, J., Millington, D. S., Mathé, A. A., Kocsis, J. H., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1801609115 · Cited by 152 · see citing works
Hoang, U., Goldacre, M. J., & James, A. C. (2014) · International Journal of Eating Disorders · doi:10.1002/eat.22249 · Cited by 149 · see citing works
Updated Meta-Analysis of Epidemiologic Studies of Pediatric Bipolar Disorder
Meter, A. V., Moreira, A. L. R., & Youngstrom, E. A. (2019) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.18r12180 · Cited by 146 · see citing works
Lifelong Impact of Early Self-Control
Caspi, A., Moffitt, T. E., & Poulton, R. (2013) · American Scientist · doi:10.1511/2013.104.352 · Cited by 142 · see citing works
Neurobiological correlates of illness progression in the recurrent affective disorders
Post, R. M., Fleming, J., & Kapczinski, F. P. (2012) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.02.004 · Cited by 139 · see citing works
Self-citationSavitz, J. B., Teague, T. K., Misaki, M., Macaluso, M., Wurfel, B. E., Meyer, M., Drevets, D. A., Yates, W. R., Gleason, O. C., Drevets, W. C., et al. (2018) · Translational Psychiatry · doi:10.1038/s41398-017-0073-7 · Cited by 138 · see citing works
DelBello, M. P., Goldman, R., Phillips, D., Deng, L., Cucchiaro, J., & Loebel, A. (2017) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2017.10.006 · Cited by 135 · see citing works
Self-citationSubstance use disorders among adolescents with bipolar spectrum disorders
Goldstein, B. I., Strober, M. A., Birmaher, B. B., Axelson, D., Esposito-Smythers, C. L., Goldstein, T. R., Leonard, H., Hunt, J., Gill, M. K., Iyengar, S., et al. (2008) · Bipolar Disorders · doi:10.1111/j.1399-5618.2008.00584.x · Cited by 132 · see citing works
Self-citationClinical Expression of Bipolar Disorder Type I as a Function of Age and Polarity at Onset
Étain, B., Lajnef, M., Bellivier, F., Mathieu, F., Raust, A., Cochet, B., Gard, S., M’Baïlara, K., Kahn, J., Wajsbrot‐Elgrabli, O., et al. (2012) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.10m06504 · Cited by 125 · see citing works
Ross, R. G., Hunter, S. K., Hoffman, M. C., McCarthy, L., Chambers, B. M., Law, A. J., Leonard, S., Zerbe, G. O., & Freedman, R. (2016) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2015.15091188 · Cited by 123 · cited 1× · see citing works
“However, an accompanying editorial by Rapoport (2016) suggested that clinical extrapolation of these findings might be premature, and instead encouraged a good diet and prevention of infection.”
BackgroundEpigenetic Regulation of Monocyte and Macrophage Function
Hoeksema, M. A., & de Winther, M. P. J. (2016) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6695 · Cited by 123 · see citing works
Early identification and high‐risk strategies for bipolar disorder
Correll, C. U., Penzner, J. B., Lencz, T., Auther, A. M., Smith, C. W., Malhotra, A. K., Kane, J. M., & Cornblatt, B. A. (2007) · Bipolar Disorders · doi:10.1111/j.1399-5618.2007.00487.x · Cited by 121 · see citing works
Expressed Emotion Moderates the Effects of Family-Focused Treatment for Bipolar Adolescents
Miklowitz, D. J., Axelson, D., George, E. L., Taylor, D. O., Schneck, C. D., Sullivan, A. E., Dickinson, L. M., & Birmaher, B. B. (2009) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e3181a0ab9d · Cited by 118 · see citing works
Self-citationFindling, R. L., Frazier, T. W., Youngstrom, E. A., McNamara, N., Stansbrey, R. J., Gracious, B., Reed, M. D., Demeter, C., & Calabrese, J. R. (2007) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v68n0519 · Cited by 115 · see citing works
Self-citationGeddes, J. R., Gardiner, A., Rendell, J., Voysey, M., Tunbridge, E., Hinds, C., Yu, L.-M., Hainsworth, J., Attenburrow, M.-J., Simon, J., et al. (2016) · The Lancet Psychiatry · doi:10.1016/s2215-0366(15)00450-2 · Cited by 112 · see citing works
Correll, C. U., Hauser, M., Penzner, J. B., Auther, A. M., Kafantaris, V., Saito, E., Olvet, D. M., Carrión, R. E., Birmaher, B. B., Chang, K., et al. (2014) · Bipolar Disorders · doi:10.1111/bdi.12194 · Cited by 111 · see citing works
Self-citationPhenotypic spectra of bipolar disorder in responders to lithium versus lamotrigine
Passmore, M. J., Garnham, J., Duffy, A., MacDougall, M., Munro, A., Slaney, C., Teehan, A., & Alda, M. (2003) · Bipolar Disorders · doi:10.1034/j.1399-5618.2003.00026.x · Cited by 109 · see citing works
Geller, B., Cooper, T. B., Zimerman, B., Frazier, J., Williams, M., Heath, J., & Warner, K. (1998) · Journal of Affective Disorders · doi:10.1016/s0165-0327(98)00178-5 · Cited by 109 · see citing works
The New News about Lithium: An Underutilized Treatment in the United States
Post, R. M. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.238 · Cited by 108 · see citing works
Self-citationDelBello, M. P., Adler, C. M., Whitsel, R. M., Stanford, K. E., & Strakowski, S. M. (2007) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v68n0520 · Cited by 103 · see citing works
Self-citationStarting lithium prophylaxis earlyv.late in bipolar disorder
Kessing, L. V., Vradi, E., & Andersen, P. K. (2014) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.113.142802 · Cited by 101 · see citing works
Pazzaglia, P. J., Post, R. M., Ketter, T. A., Callahan, A. M., Marangell, L. B., Frye, M. A., George, M. S., Kimbrell, T. A., Leverich, G. S., Cora‐Locatelli, G., et al. (1998) · Journal of Clinical Psychopharmacology · doi:10.1097/00004714-199810000-00009 · Cited by 100 · see citing works
Self-citationMaternal inflammation during pregnancy and childhood adiposity
Gaillard, R., Rifas‐Shiman, S. L., Perng, W., Oken, E., & Gillman, M. W. (2016) · Obesity · doi:10.1002/oby.21484 · Cited by 99 · see citing works
Soutullo, C. A., DelBello, M. P., Ochsner, J. E., McElroy, S. L., Taylor, S. A., Strakowski, S. M., & Keck, P. E. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(01)00336-6 · Cited by 98 · see citing works
Self-citationLifelong Impact of Early Self-Control
Moffitt, T. E., Poulton, R., & Caspi, A. (2013) · American Scientist · doi:10.1511/2013.104.1 · Cited by 98 · see citing works
Cotton, S., Luberto, C. M., Sears, R. W., Strawn, J. R., Stahl, L., Wasson, R. S., Blom, T. J., & Delbello, M. P. (2016) · Early Intervention in Psychiatry · doi:10.1111/eip.12216 · Cited by 96 · see citing works
Self-citationVitamin D deficiency and psychotic features in mentally ill adolescents: A cross-sectional study
Gracious, B., Finucane, T. L., Friedman-Campbell, M., Messing, S. P., & Parkhurst, M. N. (2012) · BMC Psychiatry · doi:10.1186/1471-244x-12-38 · Cited by 95 · see citing works
Early symptoms of mania and the role of parental risk
Findling, R. L., Youngstrom, E. A., McNamara, N., Stansbrey, R. J., Demeter, C., Bedoya, D., Kahana, S. Y., & Calabrese, J. R. (2005) · Bipolar Disorders · doi:10.1111/j.1399-5618.2005.00260.x · Cited by 94 · see citing works
Self-citationStrawn, J. R., Cotton, S., Luberto, C. M., Patino, L. R., Stahl, L., Weber, W. A., Eliassen, J. C., Sears, R. W., & DelBello, M. P. (2016) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2015.0054 · Cited by 93 · see citing works
Self-citationPersonalized medicine in psychiatry
Wium‐Andersen, I. K., Vinberg, M., Kessing, L. V., & McIntyre, R. S. (2016) · Nordic Journal of Psychiatry · doi:10.1080/08039488.2016.1216163 · Cited by 91 · see citing works
Back, S. E., McCauley, J. L., Korte, K. J., Grös, D. F., Leavitt, V., Gray, K. M., Hamner, M. B., DeSantis, S. M., Malcolm, R. J., Brady, K. T., et al. (2016) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.15m10239 · Cited by 91 · see citing works
Is High Folic Acid Intake a Risk Factor for Autism?—A Review
Wiens, D. J., & DeSoto, M. C. (2017) · Brain Sciences · doi:10.3390/brainsci7110149 · Cited by 91 · see citing works
Duffy, A. C., Alda, M., Milin, R., & Grof, P. (2007) · The Canadian Journal of Psychiatry · doi:10.1177/070674370705200606 · Cited by 90 · see citing works
Age at onset in bipolar I affective disorder in the USA and Europe
Bellivier, F., Etain, B., Malafosse, A., Henry, C., Kahn, J.-P., Elgrabli-Wajsbrot, O., Jamain, S., Azorin, J.-M., Frank, E., Scott, J., et al. (2014) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2011.639801 · Cited by 86 · see citing works
Medicare Payment for Behavioral Health Integration
Press, M. J., Howe, R., Schoenbaum, M., Cavanaugh, S., Marshall, A., Baldwin, L., & Conway, P. H. (2016) · New England Journal of Medicine · doi:10.1056/nejmp1614134 · Cited by 86 · see citing works
Miklowitz, D. J., Schneck, C. D., Walshaw, P. D., Singh, M. K., Sullivan, A. E., Suddath, R. L., Forgey Borlik, M., Sugar, C. A., & Chang, K. D. (2020) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2019.4520 · Cited by 84 · see citing works
Self-citationHafeman, D. M., Rooks, B., Merranko, J., Liao, F., Gill, M. K., Goldstein, T. R., Diler, R., Ryan, N., Goldstein, B. I., Axelson, D. A., et al. (2020) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2019.06.013 · Cited by 83 · see citing works
Self-citationClinical course of children with a depressive spectrum disorder and transient manic symptoms
Nadkarni, R., & Fristad, M. A. (2010) · Bipolar Disorders · doi:10.1111/j.1399-5618.2010.00847.x · Cited by 82 · see citing works
Birmaher, B., Merranko, J. A., Goldstein, T. R., Gill, M. K., Goldstein, B. I., Hower, H., Yen, S., Hafeman, D., Strober, M., Diler, R. S., et al. (2018) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2018.05.023 · Cited by 81 · see citing works
Self-citationRichmond-Rakerd, L., Caspi, A., Arseneault, L., Baldwin, J., Danese, A., Houts, R., Matthews, T., Wertz, J., & Moffitt, T. (2019) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2018.18060740 · Cited by 80 · see citing works
Preventative Strategies for Early-Onset Bipolar Disorder
McNamara, R. K., Nandagopal, J. J., Strakowski, S. M., & DelBello, M. P. (2010) · CNS Drugs · doi:10.2165/11539700-000000000-00000 · Cited by 79 · see citing works
Self-citationAntidepressants and Psychostimulants in Pediatric Populations: Is there an Association with Mania?
Goldsmith, M., Singh, M., & Chang, K. (2011) · Pediatric Drugs · doi:10.2165/11591660-000000000-00000 · Cited by 79 · see citing works
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., Leverich, G. S., Grunze, H., Suppes, T. M., Keck, P. E., et al. (2014) · Bipolar Disorders · doi:10.1111/bdi.12268 · Cited by 78 · see citing works
Self-citationAbou-Saleh, M. T., Müller-Oerlinghausen, B., & Coppen, A. J. (2017) · International Journal of Bipolar Disorders · doi:10.1186/s40345-017-0080-x · Cited by 74 · see citing works
Post, R. M. (2016) · Bipolar Disorders · doi:10.1111/bdi.12401 · Cited by 73 · see citing works
Self-citationFristad, M. A., Young, A. S., Vesco, A. T., Nader, E. S., Healy, K. Z., Gardner, W. P., Wolfson, H. L., & Arnold, L. E. (2015) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2015.0132 · Cited by 72 · see citing works
Berk, M., Daglas, R., Dandash, O., Yücel, M., Henry, L. P., Hallam, K. T., Macneil, C. A., Hasty, M. K., Pantelis, C., Murphy, B., et al. (2017) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.116.186833 · Cited by 71 · see citing works
Strawn, J. R., Adler, C. M., McNamara, R. K., Welge, J. A., Bitter, S. M., Mills, N. P., Barzman, D. H., Cerullo, M. A., Chang, K. D., Strakowski, S. M., et al. (2014) · Bipolar Disorders · doi:10.1111/bdi.12113 · Cited by 70 · see citing works
Self-citationTrends in Serious Emotional Disturbance Among Youths Exposed to Hurricane Katrina
McLaughlin, K. A., Fairbank, J. A., Gruber, M. J., Jones, R. T., Osofsky, J. D., Pfefferbaum, B. J., Sampson, N. A., & Kessler, R. C. (2010) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2010.06.012 · Cited by 70 · see citing works
Owais, S., Chow, C. H. T., Furtado, M., Frey, B. N., & Lieshout, R. J. V. (2018) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2018.01.005 · Cited by 69 · see citing works
Self-citationPrevalence of child sexual abuse among adults and youths with bipolar disorder: A systematic review
Maniglio, R. (2013) · Clinical Psychology Review · doi:10.1016/j.cpr.2013.03.002 · Cited by 67 · see citing works
Prevalence and Correlates of Prolonged Fatigue in a U.S. Sample of Adolescents
Lamers, F., Hickie, I. B., & Merikangas, K. R. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.12040454 · Cited by 63 · see citing works
Do young adults with bipolar disorder benefit from early intervention?
Kessing, L. V., Hansen, H. V., Christensen, E. M., Dam, H., Gluud, C. N., & Wetterslev, J. (2013) · Journal of Affective Disorders · doi:10.1016/j.jad.2013.10.001 · Cited by 63 · see citing works
Tompson, M. C., Sugar, C. A., Langer, D. A., & Asarnow, J. R. (2017) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2017.03.018 · Cited by 61 · see citing works
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., Grunze, H., Suppes, T. M., Keck, P. E., Leverich, G. S., et al. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.01.022 · Cited by 60 · see citing works
Self-citationFristad, M. A., Vesco, A. T., Young, A. S., Healy, K. Z., Nader, E. S., Gardner, W. P., Seidenfeld, A. M., Wolfson, H. L., & Arnold, L. E. (2016) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2016.1233500 · Cited by 57 · see citing works
Findling, R. L., McNamara, N., Pavuluri, M. N., Frazier, J. A., Rynn, M. A., Scheffer, R. E., Kafantaris, V., Robb, A. S., DelBello, M. P., Kowatch, R. A., et al. (2018) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2018.07.901 · Cited by 57 · see citing works
Self-citationAlbert, U., Tomassi, S., Maina, G., & Tosato, S. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.09.028 · Cited by 56 · see citing works
Geller, B., Tillman, R., Bolhofner, K., & Zimerman, B. (2010) · Bipolar Disorders · doi:10.1111/j.1399-5618.2010.00791.x · Cited by 55 · see citing works
Goldstein, T. R., Merranko, J. A., Krantz, M. L., Garcia, M., Franzen, P. L., Levenson, J. C., Axelson, D., Birmaher, B. B., & Frank, E. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.04.049 · Cited by 55 · see citing works
Self-citationRole of epigenetic factors in the development of mental illness throughout life
Guintivano, J., & Kaminsky, Z. A. (2014) · Neuroscience Research · doi:10.1016/j.neures.2014.08.003 · Cited by 54 · see citing works
Kozicky, J.-M., Torres, I. J., Silveira, L. E., Bond, D. J., Lam, R. W., & Yatham, L. N. (2014) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.13m08928 · Cited by 52 · see citing works
Arnold, L. E., Young, A. S., Belury, M. A., Cole, R. M., Gracious, B., Seidenfeld, A. M., Wolfson, H. L., & Fristad, M. A. (2017) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2016.0123 · Cited by 52 · see citing works
Cotton, S., Kraemer, K. M., Sears, R. W., Strawn, J. R., Wasson, R. S., McCune, N. R., Welge, J. A., Blom, T. J., Durling, M., & DelBello, M. P. (2019) · Early Intervention in Psychiatry · doi:10.1111/eip.12848 · Cited by 50 · see citing works
Self-citationThe Role of Circadian Rhythms in Postpartum Sleep and Mood
Gallaher, K. G. H., Slyepchenko, A., Frey, B. N., Urstad, K. H., & Dørheim, S. K. (2018) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2018.04.006 · Cited by 48 · see citing works
Self-citationPost, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., Grunze, H., Suppes, T. M., Keck, P. E., Leverich, G. S., et al. (2016) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2016.06.008 · Cited by 47 · see citing works
Self-citationThe 24‐month course of manic symptoms in children
Findling, R. L., Jo, B., Frazier, T. W., Youngstrom, E. A., Demeter, C., Fristad, M. A., Birmaher, B. B., Kowatch, R. A., Arnold, L. E., Axelson, D., et al. (2013) · Bipolar Disorders · doi:10.1111/bdi.12100 · Cited by 45 · see citing works
Self-citationKrawczak, E. M., Minuzzi, L., Hidalgo, M. P. L., & Frey, B. N. (2016) · Archives of Women s Mental Health · doi:10.1007/s00737-016-0612-x · Cited by 43 · see citing works
Self-citationPost, R. M., Chang, K., & Frye, M. A. (2013) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.12com08136 · Cited by 41 · see citing works
Self-citationHutchison, S. L., GHUMAN, J. K., Ghuman, H. S., Karpov, I. O., & Schuster, J. M. (2016) · Therapeutic Advances in Psychopharmacology · doi:10.1177/2045125316647686 · Cited by 41 · see citing works
Goldstein, B. I., Blanco, C., He, J., & Merikangas, K. R. (2016) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2016.08.010 · Cited by 40 · see citing works
Self-citationTrim the fat: the role of omega-3 fatty acids in psychopharmacology
Nasir, M., & Bloch, M. H. (2019) · Therapeutic Advances in Psychopharmacology · doi:10.1177/2045125319869791 · Cited by 37 · see citing works
Mesman, E., Birmaher, B. B., Goldstein, B. I., Goldstein, T. R., Derks, E. M., Vleeschouwer, M., Hickey, M. B., Axelson, D., Monk, K., Diler, R. S., et al. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.06.011 · Cited by 36 · see citing works
Self-citationMyriad of implications of acetyl- l -carnitine deficits in depression
Post, R. M. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1811389115 · Cited by 36 · see citing works
Self-citationThe effects on children of depressed mothers' remission and relapse over 9 months
Weissman, M. M., WICKRAMARATNE, P. J., Pilowsky, D. J., Poh, E., Hernandez, M., Batten, L. A., Flament, M. F., Stewart, J. W., & Blier, P. (2014) · Psychological Medicine · doi:10.1017/s003329171400021x · Cited by 35 · see citing works
Treatment of Bipolar Depression
Post, R. M. (2016) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2015.09.001 · Cited by 33 · see citing works
Self-citationFindling, R. L., Youngstrom, E. A., Rowles, B. M., Deyling, E. A., Lingler, J., Stansbrey, R. J., McVoy, M. K., Lytle, S., Calabrese, J. R., & McNamara, N. (2017) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2016.0160 · Cited by 33 · see citing works
Self-citationFeasibility of a Nutritional Supplement as Treatment for Pediatric Bipolar Spectrum Disorders
Frazier, E. A., Fristad, M. A., & Arnold, L. E. (2012) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2011.0270 · Cited by 32 · see citing works
Lithium Levels in Tap Water and the Mental Health Problems of Adolescents
Ando, S., Koike, S., Shimodera, S., Fujito, R., Sawada, K., Terao, T., Furukawa, T. A., Sasaki, T., Inoue, S., Asukai, N., et al. (2017) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.15m10220 · Cited by 32 · see citing works
A Pilot Pharmacotherapy Trial for Depressed Youths at High Genetic Risk for Bipolarity
Findling, R. L., Lingler, J., Rowles, B. M., McNamara, N., & Calabrese, J. R. (2008) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2008.018 · Cited by 31 · see citing works
Self-citationVesco, A. T., Young, A. S., Arnold, L. E., & Fristad, M. A. (2017) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.12830 · Cited by 31 · see citing works
C-reactive protein and response to lurasidone in patients with bipolar depression
Raison, C. L., Pikalov, A., SIU, C. O., Tsai, J., Koblan, K. S., & Loebel, A. D. (2018) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2018.08.009 · Cited by 31 · see citing works
Dysphoria: a Desperate Vitality
Stanghellini, G. (2015) · European Psychiatry · doi:10.1016/s0924-9338(15)30022-5 · Cited by 30 · see citing works
Dominick, K. C., Wink, L. K., McDougle, C. J., & Erickson, C. A. (2015) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2014.0111 · Cited by 30 · see citing works
Treatment of bipolar illness: a casebook for clinicians and patients
Post, R. M., & Leverich, G. S. (2008) · Cited by 30 · see citing works
Self-citationWhat Have We Learned about Trial Design From NIMH-Funded Pragmatic Trials?
March, J. S., KRAEMER, H. C., Trivedi, M. H., Csernansky, J. G., Davis, J. M., Ketter, T. A., & Glick, I. D. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.115 · Cited by 29 · see citing works
Parry, P. I., Allison, S. C., & Bastiampillai, T. J. (2017) · Child and Adolescent Mental Health · doi:10.1111/camh.12231 · Cited by 28 · see citing works
Findling, R. L., Pathak, S., Earley, W. R., Liu, S., & DelBello, M. P. (2013) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2012.0092 · Cited by 27 · see citing works
Self-citationNimodipine Treatment of an Adolescent with Ultradian Cycling Bipolar Affective Illness
Davanzo, P. A., KRAH, N., Kleiner, J., & McCracken, J. T. (1999) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.1999.9.51 · Cited by 24 · see citing works
Psychological interventions for young people at risk for bipolar disorder: A systematic review
Perich, T., & Mitchell, P. B. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.04.058 · Cited by 23 · see citing works
Hu, C., Torres, I. J., Qian, H., Wong, H., Halli, P., Dhanoa, T., Ahn, S., Wang, G., Bond, D. J., Lam, R. W., et al. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.08.048 · Cited by 22 · see citing works
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., Grunze, H., Suppes, T. M., Keck, P. E., Leverich, G. S., et al. (2018) · Bipolar Disorders · doi:10.1111/bdi.12668 · Cited by 22 · see citing works
Self-citationZhang, L., Liu, H., Kuang, L., Meng, H., & Zhou, X. (2019) · Child and Adolescent Psychiatry and Mental Health · doi:10.1186/s13034-019-0296-x · Cited by 21 · see citing works
Post, R. M., Leverich, G. S., Kupka, R., Keck, P. E., McElroy, S. L., Altshuler, L. L., Frye, M. A., Rowe, M., Grunze, H., Suppes, T. M., et al. (2015) · Psychiatric Genetics · doi:10.1097/ypg.0000000000000093 · Cited by 20 · see citing works
Self-citationYoung, A. S., Arnold, L. E., Wolfson, H. L., & Fristad, M. A. (2016) · Research on Child and Adolescent Psychopathology · doi:10.1007/s10802-016-0203-3 · Cited by 20 · see citing works
Age at Onset of Bipolar Disorder Related to Parental and Grandparental Illness Burden
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., Grunze, H., Suppes, T. M., Keck, P. E., Leverich, G. S., et al. (2016) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.15m09811 · Cited by 20 · see citing works
Self-citationFurther Evidence of a Cohort Effect in Bipolar Disorder
Post, R. M., Kupka, R., Keck, P. E., McElroy, S. L., Altshuler, L. L., Frye, M. A., Rowe, M., Grunze, H., Suppes, T. M., Leverich, G. S., et al. (2016) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.15m10121 · Cited by 19 · see citing works
Self-citationCourse of neurocognitive function in first treatment bipolar I disorder: One-year follow-up study
Demmo, C., Lagerberg, T. V., Aminoff, S. R., Hellvin, T., Kvitland, L. R., Simonsen, C., Haatveit, B. C., Andreassen, O. A., Melle, I. S., & Ueland, T. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2016.12.048 · Cited by 19 · see citing works
Treatment of Bipolar Illness: A Case Book for Clinicians and Patients
Frye, M. A. (2009) · Journal of Psychiatric Practice · doi:10.1097/01.pra.0000364295.39446.1a · Cited by 17 · see citing works
Castillo, M. F. R., Murata, S., Schwarz, M., Schütze, G. A., Moll, N., Martin, B., Burger, B., Weidinger, E., Mueller, N., & Halaris, A. E. (2019) · Neurology Psychiatry and Brain Research · doi:10.1016/j.npbr.2019.03.005 · Cited by 17 · see citing works
Omega-3 Supplementation for Psychotic Mania and Comorbid Anxiety in Children
Vesco, A. T., Lehmann, J., Gracious, B., Arnold, L. E., Young, A. S., & Fristad, M. A. (2015) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2013.0141 · Cited by 16 · see citing works
Raison, C. L., SIU, C. O., Pikalov, A., Tocco, M., & Loebel, A. D. (2019) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2019.12.010 · Cited by 16 · see citing works
Wozniak, J. R., Uchida, M., Faraone, S. V., Fitzgerald, M., Vaudreuil, C., Carrellas, N. W., Davis, J., Wolenski, R. A., & Biederman, J. (2017) · Bipolar Disorders · doi:10.1111/bdi.12494 · Cited by 12 · see citing works
Neuroprogression and Staging in Bipolar Disorder
Kapczinski, F., Vieta, E., Magalhães, P. V. D. S., & Berk, M. (2015) · Oxford University Press eBooks · doi:10.1093/med/9780198709992.001.0001 · Cited by 10 · see citing works
Vitamin D status of psychiatric inpatients at a community teaching hospital in the Midwest
Zeng, Q., Dellenbaugh, T., Maldonado, M., Moon, J. F., & Hornstra, R. (2015) · Nordic Journal of Psychiatry · doi:10.3109/08039488.2015.1080297 · Cited by 9 · see citing works
The Child Network for Parents to Track Their Child's Mood and Behavior
Post, R. M., Rowe, M., Kaplan, D. M., & Findling, R. L. (2017) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2017.0002 · Cited by 9 · see citing works
Self-citationDebate: Fomenting controversy regarding pediatric bipolar disorder
Goldstein, B. I., Post, R. M., & Birmaher, B. B. (2019) · Child and Adolescent Mental Health · doi:10.1111/camh.12318 · Cited by 9 · see citing works
Self-citationA Multisymptomatic Child With Bipolar Disorder
Post, R. M., Rowe, M., Kaplan, D. M., & Findling, R. L. (2017) · The Primary Care Companion For CNS Disorders · doi:10.4088/pcc.17r02122 · Cited by 8 · see citing works
Self-citationMcNamara, R. K., Moser, A. B., Jones, R. I., Jandacek, R. J., Patino, L. R., Strawn, J. R., Strakowski, S. M., & DelBello, M. P. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.10.042 · Cited by 7 · see citing works
Self-citationNew perspectives on the course and treatment of bipolar disorder
Post, R. M. (2017) · Minerva Psychiatry · doi:10.23736/s0391-1772.17.01921-5 · Cited by 7 · see citing works
Self-citationNimodipine in treatment of bipolar disorder
Romanov, D. V., Sheyanov, A. M., Samsonova, M. D., & Iuzbashian, P. G. (2023) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro202312312120 · Cited by 7 · see citing works
Vitamin D Deficiency in Children with Psychiatric Illness in a Tertiary Care Hospital in North India
Chauhan, N., Padhy, S. K., Shah, R., & Malhotra, S. (2019) · Journal of Neurosciences in Rural Practice · doi:10.4103/jnrp.jnrp_169_18 · Cited by 6 · see citing works
Ashton, M. M., Berk, M., Ng, C. H., Hopwood, M., Kavanagh, B. E., Williams, L. J., Sarris, J. J., & Dean, O. M. (2019) · BMJ Open · doi:10.1136/bmjopen-2018-025640 · Cited by 6 · see citing works
Clinical staging in bipolar disorder: a historical perspective
Post, R. M. (2015) · Oxford University Press eBooks · doi:10.1093/med/9780198709992.003.0001 · Cited by 5 · see citing works
Self-citationLacunae in the evidence for pediatric bipolar disorder: A response to the ISBD Task Force Report
Parry, P. I., Allison, S. C., & Bastiampillai, T. J. (2018) · Bipolar Disorders · doi:10.1111/bdi.12692 · Cited by 3 · see citing works
Pawełczyk, T., Grancow-Grabka, M., Kotlicka‐Antczak, M., & Pawełczyk, A. M. (2015) · European Psychiatry · doi:10.1016/s0924-9338(15)31346-8 · Cited by 1 · see citing works
Flagged first, then by citations
2 of the 167 references couldn’t be matched to a known paper.
Research works printed but not linked: 3
- Post RM, 2016b. Preventing sensitization and kindling-like progression in the recurrent affective disorders. In: Chiccetti D (Ed.), Developmental Psychopathy. John Wiley & Sons, Hoboken, NJ, pp. 971– 996.
- Post RM, Leverich GS, Kupka R, Keck PE Jr., McElroy SL, Altshuler LL, Frye MA, Rowe M, Grunze H, Suppes T, Nolen WA, 2015c. Increases in multiple psychiatric disorders in parents and grandparents of patients with bipolar disorder from the USA compared with The Netherlands and Germany. Psychiatr. Genet. 25, 194– 200. 26146875
- Ross RG, Hunter SK, Hoffman MC, McCarthy L, Chambers BM, Law AJ, Leonard S, Zerbe GO, Freedman R, 2016. Perinatal phosphatidylcholine supplementation and early childhood behavior problems: evidence for CHRNA7 moderation. Am. J. Psychiatry 173, 509– 516. 26651393 PMC5892450
Cited by
Sorted by citations
Preventive psychiatry: a blueprint for improving the mental health of young people
Fusar‐Poli, P., Correll, C. U., Arango, C., Berk, M., Patel, V., & Ioannidis, J. P. A. (2021) · World Psychiatry · doi:10.1002/wps.20869 · Cited by 497 · see citing works
Uher, R., Pavlová, B., Raduà, J., Provenzani, U., Najafi, S., Fortea, L., Ortuño, M., Nazarova, A., Perroud, N. A., Palaniyappan, L. K., et al. (2023) · World Psychiatry · doi:10.1002/wps.21147 · Cited by 135 · see citing works
Quidé, Y., Tozzi, L., Corcoran, M., Cannon, D. M., & Dauvermann, M. R. (2020) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s285540 · Cited by 51 · see citing works
The Challenges of Children with Bipolar Disorder
Post, R. M., & Grunze, H. (2021) · Medicina · doi:10.3390/medicina57060601 · Cited by 32 · see citing works
Self-citationPapolos, D. F., Teicher, M. H., & Post, R. M. (2025) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13817 · Cited by 31 · see citing works
Self-citationDouble jeopardy in the United States: Early onset bipolar disorder and treatment delay
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Rowe, M., Grunze, H., Suppes, T. M., Keck, P. E., & Nolen, W. A. (2020) · Psychiatry Research · doi:10.1016/j.psychres.2020.113274 · Cited by 28 · see citing works
Self-citationPsychosocial Treatments for Bipolar Disorder in Children and Adolescents
Brickman, H. M., & Fristad, M. A. (2022) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-072220-021237 · Cited by 28 · see citing works
25 Years of the International Bipolar Collaborative Network (BCN)
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Grunze, H., Suppes, T. M., Keck, P. E., & Nolen, W. A. (2021) · International Journal of Bipolar Disorders · doi:10.1186/s40345-020-00218-w · Cited by 15 · see citing works
Self-citationSapmaz, Ş. Y., Ermiş, Ç., Çakır, B., Öztekin, S., Guinart, D., Güney, S. A., Correll, C. U., İnal, N., & Aydemır, Ö. (2022) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2021.0071 · Cited by 13 · see citing works
Beyond the Window of Risk? The Dutch Bipolar Offspring Study: 22-Year Follow-Up
Helmink, F. G. L., Mesman, E., & Hillegers, M. H. J. (2024) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2024.05.024 · Cited by 12 · see citing works
Singh, M. K., Chang, K., Goldstein, B. I., Miklowitz, D. J., Soutullo, C. A., Youngstrom, E. A., Birmaher, B. B., Axelson, D., Post, R. M., & DelBello, M. P. (2020) · Bipolar Disorders · doi:10.1111/bdi.12987 · Cited by 6 · see citing works
Self-citationWozniak, J. R., DiSalvo, M., Farrell, A., Joshi, G., Uchida, M., Faraone, S. V., Cook, E., & Biederman, J. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.04.008 · Cited by 6 · see citing works
What Patients with Bipolar Disorder Need to Know about Lithium
Post, R. M., & RYBAKOWSKI, J. K. (2024) · Pharmaceuticals · doi:10.3390/ph17091223 · Cited by 5 · see citing works
Self-citationElevation of C-reactive protein in adolescent bipolar disorder vs. anxiety disorders
Whitney, M. S., Scott, S. L., Perez, J. A., Barnes, S., & McVoy, M. K. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.09.019 · Cited by 6 · see citing works
A shocking deficit in bipolar disorder treatment research funding
Post, R. M. (2020) · Bipolar Disorders · doi:10.1111/bdi.13010 · Cited by 5 · see citing works
Self-citationİnal, N., Ermiş, Ç., Koç, D., Aksoy, S., Karaçetin, G., Tunçtürk, M., Eray, Ş., Karabina, B., Akça, Ö. F., Ozgul, D., et al. (2021) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13333 · Cited by 5 · see citing works
Bipolar Disorder in pediatric patients: A nationwide retrospective study from 2000 to 2015
Campos, A., Ferreira, A. R., Gonçalves‐Pinho, M., Freitas, A., & Fernandes, L. P. N. S. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.10.113 · Cited by 4 · see citing works
Guillen-Burgos, H. F., Galvez-Florez, J. F., Moreno, S., Kwan, A. T. H., & McIntyre, R. S. (2024) · International Clinical Psychopharmacology · doi:10.1097/yic.0000000000000543 · Cited by 4 · see citing works
Koç, D., Ince, E., San, T., Akan, P., Paketçi, A., Böber, E., Direk, N., İnal, N., & Akay, A. P. (2022) · Psychiatry Research · doi:10.1016/j.psychres.2022.114676 · Cited by 3 · see citing works
Putative Risk Biomarkers of Bipolar Disorder in At-risk Youth
Meng, X., Zhang, S., Zhou, S., Ma, Y.-T., Yu, X., & Guan, L. (2024) · Neuroscience Bulletin · doi:10.1007/s12264-024-01219-w · Cited by 2 · see citing works
Stigma Kills Psychiatric Patients and Is Now Killing Clinical Research Too
Post, R. M. (2022) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.22l14716 · Cited by 2 · see citing works
Self-citationByrne, J. F., Lång, U., Smıth, D. J., Metsälä, J., Lahti‐Pulkkinen, M., Kajantie, E., Healy, C., & Kelleher, I. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.120394 · Cited by 1 · see citing works
The structure of affective fluctuations in a non-clinical sample
Osipova, N. N., Bardenstein, L. M., Алешкина, Г. А., & Dmitrieva, E. V. (2021) · Bulletin of Siberian Medicine · doi:10.20538/1682-0363-2021-3-79-87
Stage and symptoms of bipolar disorders
Bereda, G. (2022) · Insights on the Depression and Anxiety · doi:10.29328/journal.ida.1001030
Leng, Y. (2023) · Lecture Notes in Education Psychology and Public Media · doi:10.54254/2753-7048/7/2022926
Transtorno bipolar em crianças: análise de relato de caso 2018-2023
Talassi, G. G., Albuquerque, Á. A. C. N. D., Senhorinho, B. D. M. C., Camberimba, L. D. J. B., Arouche, R. B., Waquim, S. J. B., Freitas, G. A., Ferreira, K. J. M., de Araújo, G. C. C., Matos, E. F. B., et al. (2023) · Brazilian Journal of Health Review · doi:10.34119/bjhrv6n6-283
(2025) · Elsevier eBooks · doi:10.1016/b978-3-437-21835-4.00116-5
Additional file 1 of 25 Years of the International Bipolar Collaborative Network (BCN)
Post, R. M., Altshuler, L. L., Kupka, R., McElroy, S. L., Frye, M. A., Heinz Grunze, A., Suppes, T. M., Keck, P. E., & Nolen, W. A. (2021) · Figshare · doi:10.6084/m9.figshare.14368841
Self-citationPharmacotherapy and Latent Bipolar Disorder
Gomes, F. A. (2025) · Springer eBooks · doi:10.1007/978-3-032-01297-5_16
Korean Medication Algorithm Project for Bipolar Disorder 2026: Children and Adolescents
Yang, C.-M., Bahk, W., Woo, Y. S., Jeong, J., Seo, J. S., Yoon, S. H., Jon, D., Park, S., Kim, W., Ryu, V., et al. (2026) · 신경정신의학 · doi:10.4306/jknpa.2026.65.3.219
Perspectives on the use of lithium as a therapeutic option for bipolar disorder in 2026
Post, R. M. (2026) · Expert Review of Neurotherapeutics · doi:10.1080/14737175.2026.2734453
Self-citation
- Authors
- Post, R. M., Goldstein, B. I., Birmaher, B., Findling, R. L., Frey, B. N., DelBello, M. P., & Miklowitz, D. J.
- Affiliations
- George Washington University (US)
- Sunnybrook Health Science Centre (CA)
- University of Pittsburgh (US)
- Virginia Commonwealth University (US)
- St. Joseph’s Healthcare Hamilton (CA)
- University of Cincinnati (US)
- University of California, Los Angeles (US)
- Corresponding author
- Post, Robert M.
- ORCID
- Venue
- Journal of Affective Disorders
- Publisher
- Elsevier BV
- Published
- 2020-07
- Volume
- 272
- Pages
- 508-520
- ISSN
- 0165-0327 (ISSN-L)
- PMC
- PMC8986089
- OpenAlex
- W3010067892
- Cited by
- 31
- References
- 167
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 4 · 2023: 3 · 2022: 7 · 2021: 7 · 2020: 4
- FWCI
- 0.87
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Affective Disorders (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion, cc-by-nc-nd)
- eScholarship (California Digital Library) (submittedVersion, cc-by-nc-nd)
- Funders
- Canadian Institutes of Health Research
- National Institute of Mental Health (R01MH123575, R34MH117200, R37MH085953)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Keywords
- bipolar disorder, pediatric bipolar disorder, prevention, early intervention, vulnerable children, prodromal symptoms, family history (medicine), childhood adversity, psychosocial interventions, pharmacological interventions, safety and tolerability, illness trajectory
- MeSH terms
- Bipolar Disorder, Child, Child, Preschool, Humans, Prodromal Symptoms
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
