Major Global Coronary Artery Calcium Guidelines
Open accessAbstract
This review summarizes the framework behind global guidelines of coronary artery calcium (CAC) in atherosclerotic cardiovascular disease risk assessment, for applications in both the clinical setting and preventive therapy. By comparing similarities and differences in recommendations, this review identifies most notable common features for the application of CAC presented by different cardiovascular societies across the world. Guidelines included from North America are as follows: 1) the 2019 American College of Cardiology/American Heart Association Guideline on the Primary Prevention of Cardiovascular Disease; and 2) the 2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for Prevention of Adult Cardiovascular Disease. The authors also included European guidelines: 1) the 2019 European Society for Cardiology/European Atherosclerosis Society Guidelines for the Management of Dyslipidemias; and 2) the 2016 National Institute for Health and Care Excellence Clinical Guidelines. In this comparison, the authors also discuss: 1) the Cardiac Society of Australia and New Zealand Guidelines on CAC; 2) the Chinese Society of Cardiology Guidelines; and 3) the Japanese Atherosclerosis Society Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases. Last, they include statements made by specialty societies including the National Lipid Association, Society of Cardiovascular Computed Tomography, and U.S. Preventive Services Task Force. Utilizing an…
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Plaque features such as noncalcified or partially calcified composition have been linked to greater plaque vulnerability, and proximal lesion location may be associated with larger myocardial territories at risk in the event of an acute coronary syndrome.
“Plaque features such as noncalcified or partially calcified composition have been linked to greater plaque vulnerability, and proximal lesion location may be associated with larger myocardial territories at risk in the event of an acute coronary syndrome.27”
Current US and international guidelines recommend CAC scoring to refine ASCVD risk stratification in primary prevention.
“Current US and international guidelines recommend CAC scoring to refine atherosclerotic cardiovascular disease (ASCVD) risk stratification in primary prevention.34”
From Prognostication and clinical opportunities with AI for coronary artery calcium: a scoping review (2026) · cites this paper as [4]
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- Authors
- Golub, I. S., Termeie, O. G., Kristo, S., Schroeder, L. P., Lakshmanan, S., Shafter, A. M., Hussein, L., Verghese, D., Aldana-Bitar, J., Manubolu, V. S., & Budoff, M. J.
- Affiliations
- University of California, Los Angeles (US)
- Corresponding author
- Budoff, Matthew J.
- ORCID
- Venue
- JACC: Cardiovascular Imaging
- Publisher
- Elsevier BV
- Published
- 2023-01
- Volume
- 16
- Issue
- 1
- Pages
- 98-117
- ISSN
- 1876-7591 (ISSN-L)
- 1936-878X
- OpenAlex
- W4295775510
- Cited by
- 243
- References
- 63
- Citations by year
- 2026: 77 · 2025: 86 · 2024: 52 · 2023: 27 · 2022: 1
- FWCI
- 7.06
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- JACC. Cardiovascular imaging (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Keywords
- coronary artery calcium, atherosclerotic cardiovascular disease, cardiovascular risk assessment, dyslipidemia management, primary prevention, secondary prevention, statin therapy, aspirin therapy, coronary artery calcium score, risk stratification, guideline comparison
- MeSH terms
- Adult, Calcium, Canada, Cardiovascular Diseases, Coronary Artery Disease, Humans, Predictive Value of Tests, Prospective Studies, Risk Factors, United States, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Atherosclerosis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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