Cited by 4,945Health Promotion and Cardiovascular PreventionCoronary Interventions and DiagnosticsClinical practice guidelines implementation

2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk

Open access
Goff, David C., Lloyd-Jones, Donald M., Bennett, Glen, Coady, Sean, D’Agostino, Ralph B., Gibbons, Raymond, Greenland, Philip, Lackland, Daniel T. +9 more·2014·Journal of the American College of Cardiology

Abstract

Harmon S. Jordan, ScD, Lev Nevo, MD, Janusz Wnek, PhD Jeffrey L. Anderson, MD, FACC, FAHA, Chair , Jonathan L. Halperin, MD, FACC, FAHA, Chair-Elect , Nancy M. Albert, PhD, CCNS, CCRN, FAHA, Biykem Bozkurt, MD, PhD, FACC, FAHA, Ralph G. Brindis, MD, MPH, MACC, Lesley H. Curtis, PhD, FAHA, David

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Registry

Crossref · 10.1016/j.jacc.2013.11.005

Cites

86 of 86 references verified0 citation errors · 0 not checkable

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  • The four traditional CVD risk factors (systolic blood pressure, LDL cholesterol, fasting glucose, and per cent body fat) are often included in routine composite CVD risk algorithms to predict future CVD in clinical practice.

    “These four traditional CVD risk factors are often included in routine composite CVD risk algorithms to predict future CVD in clinical practice.10,11,14,22”

    From Aerobic, resistance, or combined exercise training and cardiovascular risk profile in overweight or obese adults: the CardioRACE trial (2024) · cites this paper as [10]

    Section 4 (page unavailable) says the Pooled Cohort Equations predict future ASCVD risk and include systolic blood pressure. But its listed variables are total and HDL cholesterol and diabetes status—not LDL cholesterol or fasting glucose—and do not include per cent body fat. Thus the guideline supports the use of a composite clinical risk algorithm, but not the claim that these four measures are included in it. (LLM, conf=0.88)

    Experimental — accuracy not yet measured
  • Human genetic analyses of variants associated with low LDL-C, increased LDL receptors, and decreased coronary heart disease support the concept.

    “This concept is further supported by human genetic analyses of variants that have been associated with low LDL-C, increased LDL receptors, and decreased coronary heart disease.58,62,63,65”

    From Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis (2016) · cites this paper as [65]

    Section 6.2, Critical Question 2 (page not supplied), discusses cumulative exposure to cardiovascular risk factors, but not genetic variants associated with low LDL-C, increased LDL receptors, and reduced coronary heart disease. Searches for those terms in our copy found no passage addressing the claimed genetic analyses. (LLM, conf=0.76)

    Experimental — accuracy not yet measured
  • Enjoyment and satisfaction are central determinants of exercise adherence.

    “Given that enjoyment and satisfaction are central determinants of exercise adherence 291 , providing a range of exercise options, which can accommodate patient preference and goals, is the key to building sustainable and engaging exercise routines.”
  • MetS tends to be clinically under-recognized.

    “but tends to be clinically under-recognized”

    From The CardioMetabolic Health Alliance (2015) · cites this paper as [29]

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Cites

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1 of the 87 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

  1. [23]Friedman GD Cutter GR Donahue RP CARDIA: study design, recruitment, and some characteristics of the examined subjects J Clin Epidemiol 1988 41 1105 1116 3204420
  2. [63]D'Agostino RB Sr. Vasan RS Pencina MJ General cardiovascular risk profile for use in primary care: the Framingham Heart Study Circulation 2008 117 743 753 18212285

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Authors
Goff, D. C., Lloyd-Jones, D. M., Bennett, G., Coady, S., D’Agostino, R. B., Gibbons, R., Greenland, P., Lackland, D. T., Levy, D., O’Donnell, C. J., Robinson, J. G., Schwartz, J. S., Shero, S. T., Smith, S. C., Sorlie, P., Stone, N. J., & Wilson, P. W. F.
Affiliations
General Department of Preventive Medicine (VN)
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
2014-07
Volume
63
Issue
25
Pages
2935-2959
ISSN
0735-1097 (ISSN-L)
OpenAlex
W2168536722
Cited by
4,945
References
87
Citations by year
2026: 122 · 2025: 207 · 2024: 294 · 2023: 375 · 2022: 443 · 2021: 504 · 2020: 440 · 2019: 469 · 2018: 474 · 2017: 484 · 2016: 439 · 2015: 391 · 2014: 285 · 2013: 13 · 2012: 1
FWCI
383.50
Type
journal article
Language
en
Update notices
erratum (2014-07-01)
Open access
Locations
  • Journal of the American College of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institutes of Health (Z99 HL999999)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
  • Health Sciences › Medicine › Surgery › Coronary Interventions and Diagnostics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Clinical practice guidelines implementation
Keywords
cardiovascular risk assessment, cardiovascular risk, risk stratification, risk prediction
MeSH terms
American Heart Association, Blood Pressure, Cardiology, Cardiovascular Diseases, Diet, Humans, Morbidity, Risk Factors, Societies, Medical, Sodium, Dietary, United States, Risk Assessment

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