2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary
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According to the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease, there is likely no lower limit on the amount of moderate-to-vigorous physical activity at which benefits for ASCVD risk start to accrue.
“According to the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease, there is likely no lower limit on the amount of moderate-to-vigorous physical activity at which benefits for ASCVD risk start to accrue, and effort should be made to promote achievement of the minimum recommended amount of physical activity (44).”
From 2021 ACC Expert Consensus Decision Pathway on the Management of ASCVD Risk Reduction in Patients With Persistent Hypertriglyceridemia (2021) · cites this paper as [44]
The Exercise and Physical Activity recommendations (page not provided) say that some moderate- or vigorous-intensity activity below the recommended minimum can reduce ASCVD risk, and recommend aiming for at least 150 minutes of moderate or 75 minutes of vigorous activity weekly. They do not establish that there is no lower limit at which benefits begin. (LLM, conf=0.85)
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“45”
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Clinical Benefit of Cardiorenal Effects of Sodium-Glucose Cotransporter 2 Inhibitors
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REES, M. C. P., Abernethy, K., Bachmann, G. A., Bretz, S., Ceauşu, I., Durmuşoğlu, F., Erkkola, R., Fistonić, I., Gambacciani, M., Geukes, M., et al. (2022) · Maturitas · doi:10.1016/j.maturitas.2021.12.001 · Cited by 105 · see citing works
Validation of a Genome-Wide Polygenic Score for Coronary Artery Disease in South Asians
Wang, M., Menon, R., Mishra, S., Patel, A. P., Chaffin, M. D., Tanneeru, D., Deshmukh, M., Mathew, O., Apte, S., Devanboo, C. S., et al. (2020) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2020.06.024 · Cited by 103 · see citing works
Self-citationStatin Use and In‐Hospital Mortality in Patients With Diabetes Mellitus and COVID‐19
Saeed, O., Castagna, F., Agalliu, I., Xue, X., Patel, S. R., Rochlani, Y. M., Kataria, R., Vukelic, S., Sims, D. B., Alvarez, C., et al. (2020) · Journal of the American Heart Association · doi:10.1161/jaha.120.018475 · Cited by 101 · see citing works
Tobacco use disorder and cardiovascular health
Benowitz, N. L., & Liakoni, E. (2021) · Addiction · doi:10.1111/add.15703 · Cited by 105 · see citing works
Clinical utility and implementation of polygenic risk scores for predicting cardiovascular disease.
Schunkert, H., di Angelantonio, E., Inouye, M., Patel, R., Ripatti, S., Widén, E., Sanderson, S. C., Kaski, J., McEvoy, J., Vardas, P., et al. (2025) · European Heart Journal · doi:10.1093/eurheartj/ehae649 · Cited by 86 · see citing works
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“38 The reduction in the risk cut-off value resulted from reduced drug acquisition costs through patent expiry, and by accumulating evidence on long term safety.”
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Diet and Lp(a): Does Dietary Change Modify Residual Cardiovascular Risk Conferred by Lp(a)?
Enkhmaa, B., Petersen, K. H., Kris‐Etherton, P. M., & Berglund, L. (2020) · Nutrients · doi:10.3390/nu12072024 · Cited by 96 · see citing works
Coronary Atherosclerosis in an Asymptomatic U.S. Population
Nasir, K., Cainzos‐Achirica, M., Elizondo, J. V., Ali, S. S., Havistin, R., Lakshman, S., Blaha, M. J., Blankstein, R., Shapiro, M. D., Arias, L., et al. (2022) · JACC. Cardiovascular imaging · doi:10.1016/j.jcmg.2022.03.010 · Cited by 91 · see citing works
Nutritional Composition of Hass Avocado Pulp
Ford, N. A., Spagnuolo, P. A., Kraft, J., & Bauer, E. E. (2023) · Foods · doi:10.3390/foods12132516 · Cited by 90 · see citing works
GlycA: a new biomarker for systemic inflammation and cardiovascular disease (CVD) risk assessment
Ballout, R. A., & Remaley, A. T. (2020) · Journal of Laboratory and Precision Medicine · doi:10.21037/jlpm.2020.03.03 · Cited by 89 · see citing works
Platelets as therapeutic targets to prevent atherosclerosis
Nording, H., Baron, L., & Langer, H. F. (2020) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2020.05.018 · Cited by 89 · see citing works
Role of Dipeptidyl Peptidase 4 Inhibitors in Antidiabetic Treatment
Yin, R., Xu, Y., Wang, X., Yang, L., & Zhao, D. (2022) · Molecules · doi:10.3390/molecules27103055 · Cited by 95 · see citing works
Ceramide Scores Predict Cardiovascular Risk in the Community
Vasile, V. C., Meeusen, J. W., Medina‐Inojosa, J. R., Donato, L. J., Scott, C. G., Hyun, M., Vinciguerra, M., Rodeheffer, R. R., López-Jiménez, F. A., & Jaffe, A. S. (2021) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.120.315530 · Cited by 88 · see citing works
Primary Prevention of Subclinical Atherosclerosis in Young Adults: JACC Review Topic of the Week.
Devesa, A., Ibáñez, B., Malick, W., Tinuoye, E. O., Bustamante, J., Peyra, C., Rosenson, R. S., Bhatt, D., Stone, G. W., & Fuster, V. (2023) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2023.09.817 · Cited by 77 · see citing works
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Artificial intelligence in cardiac radiology
van Assen, M., Muscogiuri, G., Caruso, D., Lee, S., Laghi, A., & Cecco, C. N. D. (2020) · La radiologia medica · doi:10.1007/s11547-020-01277-w · Cited by 87 · see citing works
Cardiovascular Disease Screening in Women: Leveraging Artificial Intelligence and Digital Tools
Adedinsewo, D. A., Pollak, A. W., Phillips, S. D., Smith, T. L., Svatikova, A., Hayes, S. N., Mulvagh, S. L., Norris, C., Roger, V. L., Noseworthy, P. A., et al. (2022) · Circulation Research · doi:10.1161/circresaha.121.319876 · Cited by 92 · see citing works
Obstructive Sleep Apnea and Cardiometabolic Disease: Obesity, Hypertension, and Diabetes
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Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis via COX-1
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Lipoprotein(a): Knowns, unknowns and uncertainties
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Perone, F., Bernardi, M., Redheuil, A. B., Mafrica, D., Conte, E., Spadafora, L., Ecarnot, F., Tokgözoğlu, L. S., Santos‐Gallego, C. G., Kaiser, S., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12175563 · Cited by 78 · see citing works
NAFLD and Cardiovascular Diseases: Epidemiological, Mechanistic and Therapeutic Considerations
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Heterogeneity in statin responses explained by variation in the human gut microbiome
Wilmanski, T. M., Kornilov, S. A., Diener, C., Conomos, M. P., Lovejoy, J. C., Paola Sebastiani, B., ORWOLL, E. S., Hood, L., Price, N. D., Rappaport, N., et al. (2022) · Med · doi:10.1016/j.medj.2022.04.007 · Cited by 75 · see citing works
Reducing disparities in adverse pregnancy outcomes in the United States
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Top 10 dietary strategies for atherosclerotic cardiovascular risk reduction
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Tomson, C., Cheung, A. K., Mann, J. F. E., Chang, T. I., Cushman, W. C., Furth, S. L., Hou, F. F., Knoll, G. A., Muntner, P., Pecoits‐Filho, R., et al. (2021) · Annals of Internal Medicine · doi:10.7326/m21-0834 · Cited by 68 · see citing works
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The effect of green Mediterranean diet on cardiometabolic risk; a randomised controlled trial
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“…was de fi ned as “ ESG is inferior to LSG by more than 10% TWL, ” whereupon signi fi cant rejection of the null hypothesis with a P .05 would allow the inference that ESG was not inferior to LSG. Analysis of follow-up data from 6, 12, 24, and 36 months after each intervention was performed.”
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Differential Associations of Chronic Inflammatory Diseases With Incident Heart Failure
Prasada, S., Rivera, A. S., Nishtala, A., Pawlowski, A. E., Sinha, A., Bundy, J. D., Chadha, S. A., Ahmad, F. S., Khan, S. S., Achenbach, C. J., et al. (2020) · JACC Heart Failure · doi:10.1016/j.jchf.2019.11.013 · Cited by 64 · see citing works
Self-citation
- Authors
- Arnett, D. K., Blumenthal, R. S., Albert, M. A., Buroker, A. B., Goldberger, Z. D., Hahn, E. J., Himmelfarb, C. D., Khera, A., Lloyd-Jones, D., McEvoy, J. W., Michos, E. D., Miedema, M. D., Muñoz, D., Smith, S. C., Virani, S. S., Williams, K. A., Yeboah, J., & Ziaeian, B.
- ORCID
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2019-09
- Volume
- 74
- Issue
- 10
- Pages
- 1376-1414
- ISSN
- 0735-1097 (ISSN-L)
- PMC
- PMC8344373
- OpenAlex
- W2984766121
- Cited by
- 1,193
- References
- 286
- Citations by year
- 2026: 87 · 2025: 140 · 2024: 131 · 2023: 167 · 2022: 191 · 2021: 207 · 2020: 191 · 2019: 79
- FWCI
- 153.80
- Type
- journal article
- Language
- en
- Update notices
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- American Heart Association (17SDG33630113)
- National Institutes of Health (KL2TR001882)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Surgery › Lipoproteins and Cardiovascular Health
- Keywords
- primary prevention, cardiovascular disease, cardiovascular risk factors, cardiovascular disease prevention
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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