Cited by 9Cardiac Arrest and ResuscitationClinical Nutrition and GastroenterologyNosocomial Infections in ICU

Early enteral nutrition in patients with out-of-hospital cardiac arrest under target temperature management was associated with a lower 7-day bacteremia rate: A post-hoc analysis of a retrospective cohort study

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Tsai, Yu-Chi, Yin, Chun-Hao, Chen, Jin-Shuen, Chen, Yao-Shen, Huang, Shih-Chung, Chen, Jui-Kuang·2024·Journal of Microbiology, Immunology and Infection

Abstract

Introduction Early enteral nutrition (EN) is a nutritional strategy for reducing the incidence of in-hospital infections. However, the benefits of early EN, under targeted temperature management (TTM) in patients with out-of-hospital cardiac arrest (OHCA), remain unclear. We aimed to evaluate the effect of early EN on the infective complications of OHCA patients who underwent TTM. Methods We retrospectively searched the clinical databases of two adult emergency tertiary referral hospitals in southern Taiwan and identified patients admitted for OHCA who underwent TTM between 2017 and 2022. The 85 enrolled patients were divided into two groups based on timing: early EN (EN within 48 h of admission) and delayed EN (EN > 48 h after admission). Clinical outcomes of 7-day infective complications between the two groups were analyzed. Results Early EN was provided to 57 (67 %) of 85 patients and delayed EN was provided to the remaining 28 (33 %) patients. No significant differences in baseline patient characteristics were observed between the two groups. In addition, no differences in clinical outcomes were observed, except that the early EN group had a lower 7-day bacteremia rate (5.3 % vs. 26.9 %, p = 0.013). Gram-negative bacteria were the major pathogen among the 7-day infective complications. Conclusion In OHCA patients treated with TTM, early EN was associated with a lower 7-day bacteremia rate. Furthermore, the application of early EN in this population was well tolerated with…

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Crossref · 10.1016/j.jmii.2023.12.007

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Authors
Tsai, Y.-C., Yin, C.-H., Chen, J.-S., Chen, Y.-S., Huang, S.-C., & Chen, J.-K.
Affiliations
  • Tri-Service General Hospital (TW)
  • National Sun Yat-sen University (TW)
  • National Yang Ming Chiao Tung University (TW)
Corresponding author
Chen, Jui-Kuang
Venue
Journal of Microbiology, Immunology and Infection
Publisher
Elsevier BV
Published
2024-04
Volume
57
Issue
2
Pages
309-319
ISSN
1684-1182 (ISSN-L)
OpenAlex
W4390457862
Cited by
9
References
38
Citations by year
2026: 5 · 2025: 3 · 2024: 1
FWCI
2.76
Type
journal article
Language
en
Open access
Locations
  • Journal of Microbiology Immunology and Infection (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Veterans Affairs Council
Topics
  • Health Sciences › Medicine › Emergency Medicine › Cardiac Arrest and Resuscitation
  • Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
  • Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Nosocomial Infections in ICU
Keywords
early enteral nutrition, out-of-hospital cardiac arrest, targeted temperature management, bacteremia, post-cardiac arrest syndrome, infection control, Gram-negative bacteria, timing of enteral feeding, post-resuscitation care
MeSH terms
Enteral Nutrition, Humans, Retrospective Studies, Temperature, Bacteremia, Out-of-Hospital Cardiac Arrest

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