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Cited by 249Intestinal and Peritoneal AdhesionsHernia repair and managementSurgical Sutures and Adhesives

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Abdominal Adhesions: Current and Novel Therapies

Ward, Brian C., Panitch, Alyssa·2011·Journal of Surgical Research
DOI 10.1016/j.jss.2009.09.015
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Abstract

An adhesion occurs when two tissues that normally freely move past each other attach via a fibrous bridge. Abdominal adhesions place a tremendous clinical and financial burden on public health. Adhesions develop after nearly every abdominal surgery, commonly causing female infertility, chronic pelvic pain, and, most frequently, small bowel obstruction. A National Hospital Discharge Survey of hospitalizations between 1998 and 2002 reported that 18.1% of hospitalizations were related to abdominal adhesions annually accounting for 948,000 days of inpatient care at an estimated cost of $1.18 billion. This review discusses the current or proposed therapies for abdominal adhesions. While many therapies for abdominal adhesions have been attempted, the need for a definitive therapy to prevent or even reduce abdominal adhesions still exists.

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Metadata

Authors
Ward, B. C., & Panitch, A.
Affiliations
Purdue University West Lafayette (US)
Corresponding author
Panitch, Alyssa
ORCID
Venue
Journal of Surgical Research
Publisher
Elsevier BV
Published
2011-01
Volume
165
Issue
1
Pages
91-111
ISSN
0022-4804 (ISSN-L)
DOI
10.1016/j.jss.2009.09.015
OpenAlex
W2122017924
Cited by
249
References
315
Citations by year
2026: 11 · 2025: 17 · 2024: 13 · 2023: 18 · 2022: 17 · 2021: 14 · 2020: 18 · 2019: 19 · 2018: 21 · 2017: 18 · 2016: 15 · 2015: 16 · 2014: 21 · 2013: 12 · 2012: 10
FWCI
1.01
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Journal of Surgical Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Heart, Lung, and Blood Institute (K25HL074968)
  • National Institute of General Medical Sciences (GM 077229, T32GM077229)
Topics
  • Health Sciences › Medicine › Surgery › Intestinal and Peritoneal Adhesions
  • Health Sciences › Medicine › Surgery › Hernia repair and management
  • Health Sciences › Medicine › Surgery › Surgical Sutures and Adhesives
Keywords
peritoneal adhesions, postoperative adhesions, adhesion prevention, small bowel obstruction, female infertility, chronic pelvic pain, abdominal surgery complications
MeSH terms
Abdomen, Tissue Adhesions, Animals, Cellulose, Oxidized, Humans, Hyaluronic Acid

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