Long lasting consequences of cannabis exposure in adolescence

The adolescent brain and age-related behavioral manifestations

Spear, L. P. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(00)00014-2 · Cited by 5,433 · see citing works

A new one-trial test for neurobiological studies of memory in rats. 1: behavioral data

Ennaceur, A., & Delacour, J. (1988) · Behavioural Brain Research · doi:10.1016/0166-4328(88)90157-x · Cited by 3,223 · see citing works

Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.

Rice, D., & Barone, S. (2000) · Environmental Health Perspectives · doi:10.1289/ehp.00108s3511 · Cited by 2,944 · see citing works

Cannabinoid receptor localization in brain.

Herkenham, M., Lynn, A. B., Little, M. D., Johnson, M. R., Melvin, L. S., de Costa, B. R., & Rice, K. C. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.5.1932 · Cited by 2,321 · see citing works

Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses

Wilson, R. I., & Nicoll, R. A. (2001) · Nature · doi:10.1038/35069076 · Cited by 1,607 · see citing works

Role of Endogenous Cannabinoids in Synaptic Signaling

Freund, T. F., Katona, I., & Piomelli, D. (2003) · Physiological Reviews · doi:10.1152/physrev.00004.2003 · Cited by 1,567 · see citing works

Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study.

Arseneault, L., Cannon, M., Poulton, R., Murray, R., Caspi, A., & Moffitt, T. E. (2002) · BMJ · doi:10.1136/bmj.325.7374.1212 · Cited by 1,399 · see citing works

The many faces of CREB

Carlezon, W. A., Duman, R. S., & Nestler, E. J. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.06.005 · Cited by 1,351 · see citing works

Endocannabinoid Signaling in the Brain

Wilson, R. I., & Nicoll, R. A. (2002) · Science · doi:10.1126/science.1063545 · Cited by 1,260 · see citing works

Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus

Nibuya, M., Nestler, E., & Duman, R. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-07-02365.1996 · Cited by 1,206 · see citing works

Cannabis use and mental health in young people: cohort study.

Patton, G. C., Coffey, C., Carlin, J. B., Degenhardt, L., Lynskey, M., & Hall, W. (2002) · BMJ · doi:10.1136/bmj.325.7374.1195 · Cited by 997 · see citing works

Causal association between cannabis and psychosis: examination of the evidence

Arseneault, L., Cannon, M. D., Witton, J., & Murray, R. M. (2004) · The British Journal of Psychiatry · doi:10.1192/bjp.184.2.110 · Cited by 909 · see citing works

Critical Periods of Vulnerability for the Developing Nervous System: Evidence from Humans and Animal Models

Rice, D. C., & Barone, S. (2000) · Environmental Health Perspectives · doi:10.2307/3454543 · Cited by 712 · see citing works

Cannabis use and psychosocial adjustment in adolescence and young adulthood

Fergusson, D. M., Horwood, L. J., & Swain‐Campbell, N. (2002) · Addiction · doi:10.1046/j.1360-0443.2002.00103.x · Cited by 563 · see citing works

Presynaptic Specificity of Endocannabinoid Signaling in the Hippocampus

Wilson, R. I., Kunos, G., & Nicoll, R. A. (2001) · Neuron · doi:10.1016/s0896-6273(01)00372-5 · Cited by 543 · see citing works

Early-onset cannabis use and cognitive deficits: what is the nature of the association?

Pope, H. G., Gruber, A. J., Hudson, J. I., Cohane, G. H., Huestis, M. A., & Yurgelun-Todd, D. A. (2003) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(02)00334-4 · Cited by 541 · see citing works

cAMP Response Element-Mediated Gene Transcription Is Upregulated by Chronic Antidepressant Treatment

Thome, J., Sakai, N., Shin, K.-H., Steffen, C., Zhang, Y.-J., Impey, S., Storm, D. R., & Duman, R. S. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-11-04030.2000 · Cited by 507 · see citing works

Chronic Pubertal, but not Adult Chronic Cannabinoid Treatment Impairs Sensorimotor Gating, Recognition Memory, and the Performance in a Progressive Ratio Task in Adult Rats

Schneider, M., & Koch, M. (2003) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300225 · Cited by 425 · see citing works

Specific attentional dysfunction in adults following early start of cannabis use

Ehrenreich, H., Kunert, H. J., Moeller, M. R., Poser, W., Schilling, L., Gigerenzer, G., Hoehe, M. R., & Rinn, T. (1999) · Psychopharmacology · doi:10.1007/s002130050892 · Cited by 387 · see citing works

Sensation seeking, puberty, and nicotine, alcohol, and marijuana use in adolescence

MARTIN, C. A., KELLY, T. H., RAYENS, M. K., BROGLI, B. R., BRENZEL, A., SMITH, W. J., & OMAR, H. A. (2002) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200212000-00022 · Cited by 365 · see citing works

Chronic Δ9-Tetrahydrocannabinol During Adolescence Provokes Sex-Dependent Changes in the Emotional Profile in Adult Rats: Behavioral and Biochemical Correlates

Rubino, T., Vigano', D., Realini, N., Guidali, C., Braida, D., Capurro, V., Castiglioni, C., Cherubino, F., Romualdi, P., Candeletti, S., et al. (2008) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301664 · Cited by 345 · see citing works

Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect

Newton, S. S., Thome, J., Wallace, T. L., Shirayama, Y., Schlesinger, L., Sakai, N., Chen, J., Neve, R., Nestler, E. J., & Duman, R. S. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-24-10883.2002 · Cited by 313 · see citing works

Presence of cannabinoid binding sites in the brain from early postnatal ages

de Fonseca, F. R., Ramos, J. A., Bonnin, A., & Fernández‐Ruíz, J. (1993) · Neuroreport · doi:10.1097/00001756-199302000-00005 · Cited by 297 · see citing works

Adolescent Rats Find Repeated Δ9-THC Less Aversive Than Adult Rats but Display Greater Residual Cognitive Deficits and Changes in Hippocampal Protein Expression Following Exposure

Quinn, H. R., Matsumoto, I., Callaghan, P. D., Long, L. E., Arnold, J. C., Gunasekaran, N., Thompson, M. R., Dawson, B., Mallet, P. E., Kashem, M. A., et al. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301475 · Cited by 293 · see citing works

Chronic cannabinoid exposure produces lasting memory impairment and increased anxiety in adolescent but not adult rats

O’Shea, M., Singh, M. E., McGregor, I. S., & Mallet, P. E. (2004) · Journal of Psychopharmacology · doi:10.1177/0269881104047277 · Cited by 292 · see citing works

Adolescent Cannabis Exposure Alters Opiate Intake and Opioid Limbic Neuronal Populations in Adult Rats

Ellgren, M., Spano, S., & Hurd, Y. L. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301127 · Cited by 287 · see citing works

Cannabis and Anxiety and Depression in Young Adults

Hayatbakhsh, M. R., Najman, J. M., Jamrozik, K. D., Mamun, A. A., Alati, R., & Bor, W. (2007) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e31802dc54d · Cited by 266 · see citing works

Puberty and the onset of substance use and abuse

Patton, G. C., McMorris, B. J., Toumbourou, J. W., Hemphill, S. A., Donath, S., & Catalano, R. F. (2004) · Pediatrics · doi:10.1542/peds.2003-0626-f · Cited by 254 · see citing works

Repeated cannabinoid exposure during perinatal, adolescent or early adult ages produces similar longlasting deficits in object recognition and reduced social interaction in rats

O’Shea, M., McGregor, I. S., & Mallet, P. E. (2006) · Journal of Psychopharmacology · doi:10.1177/0269881106065188 · Cited by 230 · see citing works

Retrograde signaling by endocannabinoids

Kreitzer, A. C. (2002) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(02)00328-8 · Cited by 220 · see citing works

Relationships between frequency and quantity of marijuana use and last year proxy dependence among adolescents and adults in the United States.

Chen, K. W., Kandel, D., & Davies, M. (1997) · Drug and Alcohol Dependence · doi:10.1016/s0376-8716(97)00047-1 · Cited by 208 · see citing works

Mental health of teenagers who use cannabis

Rey, J. M., SAWYER, M. G., Raphael, B., Patton, G. C., & Lynskey, M. T. (2002) · The British Journal of Psychiatry · doi:10.1192/bjp.180.3.216 · Cited by 207 · see citing works

Chronic antidepressant treatment selectively increases expression of plasticity-related proteins in the hippocampus and medial prefrontal cortex of the rat

Sairanen, M., O’Leary, O. F., Knuuttila, J. E., & Castrén, E. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.069 · Cited by 206 · see citing works

Adolescent exposure to cannabinoids induces long-lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons.

Pistis, M., Perra, S., Pillolla, G., Melis, M., Muntoni, A. L., & Gessa, G. L. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.05.006 · Cited by 194 · see citing works

Selective Phosphorylation of Nuclear CREB by Fluoxetine is Linked to Activation of CaM Kinase IV and MAP Kinase Cascades

Tiraboschi, E., Tardito, D., Kasahara, J., Moraschi, S., Pruneri, P., Gennarelli, M., Racagni, G., & Popoli, M. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300488 · Cited by 186 · see citing works

Short-term Memory Impairment in Cannabis-Dependent Adolescents

Schwartz, R. H. (1989) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/archpedi.1989.02150220110030 · Cited by 179 · see citing works

Abnormal Expression and Functional Characteristics of Cyclic Adenosine Monophosphate Response Element Binding Protein in Postmortem Brain of Suicide Subjects

Dwivedi, Y., Rao, J. S., Rizavi, H. S., Kotowski, J., Conley, R. R., Roberts, R. C., Tamminga, C. A., & Pandey, G. N. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.3.273 · Cited by 177 · see citing works

The ontogeny of cannabinoid receptors in the brain of postnatal and aging rats

Belue, R. C., Howlett, A. C., Westlake, T. M., & Hutchings, D. E. (1995) · Neurotoxicology and Teratology · doi:10.1016/0892-0362(94)00053-g · Cited by 154 · see citing works

TESTING THE GATEWAY HYPOTHESIS

Kandel, D. B., Yamaguchi, K., & Klein, L. C. (2006) · Addiction · doi:10.1111/j.1360-0443.2006.01426.x · Cited by 153 · see citing works

Cannabinoid-Induced Presynaptic Inhibition of Glutamatergic EPSCs in Substantia Gelatinosa Neurons of the Rat Spinal Cord

Morisset, V., & Urbán, L. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.86.1.40 · Cited by 152 · see citing works

Differential effects of delta9-THC on learning in adolescent and adult rats

Cha, Y. M., White, A. M., Kuhn, C. M., Wilson, W. A., & Swartzwelder, H. S. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.03.006 · Cited by 149 · see citing works

Chronic treatment with CP 55,940 during the peri-adolescent period differentially affects the behavioural responses of male and female rats in adulthood

Fernández, J. M. B., Marín, S., Fernández, B., Marco, E. M., Rubio, M., Guaza, C., Ambrosio, E., & Viveros, M. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1550-7 · Cited by 137 · see citing works

Cannabinoids and gene expression during brain development

Fernández‐Ruíz, J., Gómez‐Ruíz, M., Hernández, M., de Miguel, R., & Ramos, J. A. (2004) · Neurotoxicity Research · doi:10.1007/bf03033314 · Cited by 110 · see citing works

Possible age‐associated bias in reporting of clinical features of drug dependence: epidemiological evidence on adolescent‐onset marijuana use

Chen, C., & Anthony, J. C. (2002) · Addiction · doi:10.1046/j.1360-0443.2003.00237.x · Cited by 110 · see citing works

Growth and pubertal milestones during adolescence in offspring prenatally exposed to cigarettes and marihuana

Fried, P. A., James, D., & Watkinson, B. (2001) · Neurotoxicology and Teratology · doi:10.1016/s0892-0362(01)00161-1 · Cited by 110 · see citing works

Sex differences in the effects of Δ9-tetrahydrocannabinol on spatial learning in adolescent and adult rats

Cha, Y. M., Jones, K. H., Kuhn, C. M., Wilson, W. A., & Swartzwelder, S. H. (2007) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e3282ee7b7e · Cited by 108 · see citing works

Augmented Acquisition of Cocaine Self-Administration and Altered Brain Glucose Metabolism in Adult Female but not Male Rats Exposed to a Cannabinoid Agonist during Adolescence

Higuera‐Matas, A., Soto‐Montenegro, M. L., Olmo, N. D., Miguéns, M., Torres, I., Vaquero, J. J., Sánchez, J. C., Garcı́a-Lecumberri, C., Desco, M., & Ambrosio, E. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301467 · Cited by 90 · see citing works

Marijuana use among adolescents

Gruber, A. J., & Pope, H. G. (2002) · Pediatric Clinics of North America · doi:10.1016/s0031-3955(01)00011-6 · Cited by 85 · see citing works

The effect of chronic peripubertal cannabinoid treatment on deficient object recognition memory in rats after neonatal mPFC lesion

SCHNEIDER, M., & Koch, M. (2006) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2006.03.009 · Cited by 71 · see citing works

Cannabinoid receptors in developing rats: detection of mRNA and receptor binding

McLaughlin, C. (1994) · Drug and Alcohol Dependence · doi:10.1016/0376-8716(94)90006-x · Cited by 56 · see citing works

Glutamatergic synaptic responses and long-term potentiation are impaired in the CA1 hippocampal area of calbindin D28k-deficient mice

Jouvenceau, A., Potier, B., Battini, R., Ferrari, S. M., Dutar, P., & Billard, J. (1999) · Synapse · doi:10.1002/(sici)1098-2396(19990901)33:3 · Cited by 52 · see citing works

Brain Development, X

Seeman, P. M. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.2.168 · Cited by 45 · see citing works

Amphetamine effects on dopamine levels and behavior following cannabinoid exposure during adolescence

Ellgren, M., Hurd, Y. L., & Franck, J. (2004) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2004.06.048 · Cited by 35 · see citing works

Developmental Vicissitudes That Promote Drug Abuse in Adolescents

Trad, P. V. (1994) · The American Journal of Drug and Alcohol Abuse · doi:10.3109/00952999409109184 · Cited by 14 · see citing works

Untitled work

(1997) · doi:10.1002/(sici)1098-2396(199707)26:3

Association Between Cannabis and Psychosis: Epidemiologic Evidence

Gage, S. H., Hickman, M., & Zammit, S. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.08.001 · Cited by 379 · see citing works

Cannabinoid and opioid interactions: implications for opiate dependence and withdrawal

Scavone, J. L., Sterling, R. C., & Van Bockstaele, E. J. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.04.034 · Cited by 209 · see citing works

Does puberty mark a transition in sensitive periods for plasticity in the associative neocortex?

Piekarski, D. J., Johnson, C. M., Boivin, J. R., Thomas, A. W., Lin, W. C., Delevich, K., M. Galarce, E., & Wilbrecht, L. (2017) · Brain Research · doi:10.1016/j.brainres.2016.08.042 · Cited by 175 · see citing works

Causal Inference in Developmental Origins of Health and Disease (DOHaD) Research

Gage, S. H., Munafò, M. R., & Davey Smith, G. (2016) · Annual Review of Psychology · doi:10.1146/annurev-psych-122414-033352 · Cited by 173 · see citing works

Considering Cannabis: The Effects of Regular Cannabis Use on Neurocognition in Adolescents and Young Adults

Lisdahl, K. M., Wright, N. E., Medina-Kirchner, C., Maple, K. E., & Shollenbarger, S. (2014) · Current Addiction Reports · doi:10.1007/s40429-014-0019-6 · Cited by 160 · see citing works

Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse

Korpi, E. R., den Hollander, B., Farooq, U., Vashchinkina, E., Rajkumar, R., Nutt, D. J., Hyytiä, P., & Dawe, G. S. (2015) · Pharmacological Reviews · doi:10.1124/pr.115.010967 · Cited by 148 · see citing works

Critical age windows for neurodevelopmental psychiatric disorders: evidence from animal models

Marco, E. M., Macrì, S., & Laviola, G. (2011) · Neurotoxicity Research · doi:10.1007/s12640-010-9205-z · Cited by 144 · see citing works

Frequent Low-Dose Δ9-Tetrahydrocannabinol in Adolescence Disrupts Microglia Homeostasis and Disables Responses to Microbial Infection and Social Stress in Young Adulthood

Lee, H.-L., Jung, K.-M., Fotio, Y., Squire, E., Palese, F., Lin, L., Torrens, A., Ahmed, F., Mabou Tagne, A., Ramirez, J., et al. (2022) · Biological Psychiatry · doi:10.1016/j.biopsych.2022.04.017 · Cited by 38 · see citing works

Comparison between delta-9-tetrahydrocannabinol and cannabis extract on resorption rate in mice.

Abel, E. L., & Dintcheff, B. A. (1986) · PubMed

Effects of delta-9-tetrahydrocannabinol on social behaviour in the laboratory mouse and rat

Cutler, M. G., & Mackintosh, J. H. (1975) · Psychopharmacology · doi:10.1007/bf00428908 · Cited by 24 · see citing works

Rapid tolerance to Δ9-tetrahydrocannabinol and cross-tolerance between ethanol and Δ9-tetrahydrocannabinol in mice

Silva, G. E. D., Morato, G. S., & Takahashi, R. N. (2001) · European Journal of Pharmacology · doi:10.1016/s0014-2999(01)01449-2 · Cited by 25 · see citing works

Influence of cannabis and delta-9-tetrahydrocannabinol on the biochemistry of the male reproductive organs

Chakravarty, I., & Ghosh, J. J. (1981) · Biochemical Pharmacology · doi:10.1016/0006-2952(81)90053-8 · Cited by 10 · see citing works

Asymmetrical effect of delta-9-tetrahydrocannabinol (THC) on striatal dopamine and behavior.

Dh, W., & Glick, S. D. (1973) · PubMed · Cited by 10 · see citing works