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Cited by 192

The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.

Spatially and temporally controlled hydrogels for tissue engineering

Open access
Leijten, Jeroen, Seo, Jungmok, Yue, Kan, Trujillo-de Santiago, Grissel, Tamayol, Ali, Ruiz-Esparza, Guillermo U., Shin, Su Ryon, Sharifi, Roholah, Noshadi, Iman, Álvarez, Mario Moisés, Zhang, Yu Shrike, Khademhosseini, Ali·2017·Materials Science and Engineering: R: Reports

Abstract

Summary Recent years have seen tremendous advances in the field of hydrogel-based biomaterials. One of the most prominent revolutions in this field has been the integration of elements or techniques that enable spatial and temporal control over hydrogels’ properties and functions. Here, we critically review the emerging progress of spatiotemporal control over biomaterial properties towards the development of functional engineered tissue constructs. Specifically, we will highlight the main advances in the spatial control of biomaterials, such as surface modification, microfabrication, photo-patterning, and three-dimensional (3D) bioprinting, as well as advances in the temporal control of biomaterials, such as controlled release of molecules, photocleaving of proteins, and controlled hydrogel degradation. We believe that the development and integration of these techniques will drive the engineering of next-generation engineered tissues.

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Crossref · 10.1016/j.mser.2017.07.001

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Metadata

Authors
Leijten, J., Seo, J., Yue, K., Trujillo-de Santiago, G., Tamayol, A., Ruiz-Esparza, G. U., Shin, S. R., Sharifi, R., Noshadi, I., Álvarez, M. M., Zhang, Y. S., & Khademhosseini, A.
Venue
Materials Science and Engineering: R: Reports
Publisher
Elsevier BV
Published
2017-09
Volume
119
Pages
1-35
ISSN
0927-796X (ISSN-L)
OpenAlex
W2736785778
Cited by
192
References
26
FWCI
6.84
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Spatially and temporally controlled hydrogels for tissue engineering. https://app.cochat.ai/papers/10.1016/j.mser.2017.07.001
The paper
Leijten, J., Seo, J., Yue, K., Trujillo-de Santiago, G., Tamayol, A., Ruiz-Esparza, G. U., Shin, S. R., Sharifi, R., Noshadi, I., Álvarez, M. M., Zhang, Y. S., & Khademhosseini, A. (2017). Spatially and temporally controlled hydrogels for tissue engineering. Materials Science and Engineering: R: Reports. https://doi.org/10.1016/j.mser.2017.07.001

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.