The DOI matches its Crossref record; 86 of the 89 references it cites were found in a registry or an index.
Black sheep get the blues: A psychobiological model of social rejection and depression
Open accessAbstract
Major life events involving social rejection are strongly associated with onset of depression. To account for this relation, we propose a psychobiological model in which rejection-related stressors elicit a distinct and integrated set of cognitive, emotional, and biological changes that may evoke depression. In this model, social rejection events activate brain regions involved in processing negative affect and rejection-related distress (e.g., anterior insula, dorsal anterior cingulate cortex). They also elicit negative self-referential cognitions (e.g., "I'm undesirable," "Other people don't like me") and related self-conscious emotions (e.g., shame, humiliation). Downstream biological consequences include upregulation of the hypothalamic-pituitary-adrenal axis, sympathetic-adrenal-medullary axis, and inflammatory response. Pro-inflammatory cytokines play an important role in this process because they induce a constellation of depressotypic behaviors called sickness behaviors. Although these changes can be short-lived, sustained inflammation may occur via glucocorticoid resistance, catecholamines, sympathetic innervation of immune organs, and immune cell aging. This response also may be moderated by several factors, including prior life stress, prior depression, and genes implicated in stress reactivity.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“adverse social experiences characterized by loss or threat activate proinflammatory cytokine activity (Giletta et al. 2018, Slavich & Cole 2013) and trigger alterations in the genes regulating proinflammatory cytokine production (Slavich et al. 2010)”
From Adolescent Suicide as a Failure of Acute Stress-Response Systems. (2019) · cites this paper as Slavich et al. 2010
The cited source says what the claim attributes to it.
In the citing paper
“a primacy for interpersonal loss and social rejection life events in predicting depression emerges even when interpersonal loss events are compared to other stressors of the same severity level”
From From stress to inflammation and major depressive disorder: A social signal transduction theory of depression. (2014) · cites this paper as Slavich, O'Donovan, et al., 2010
The cited source says what the claim attributes to it.
In the citing paper
“a substantial body of evidence now exists showing that major life events involving interpersonal loss or social rejection are particularly strongly related to MDD”
From From stress to inflammation and major depressive disorder: A social signal transduction theory of depression. (2014) · cites this paper as Slavich, O'Donovan, et al., 2010
The cited source says what the claim attributes to it.
In the citing paper
“social stress-related reductions in glucocorticoid sensitivity may be one mechanism linking social threat and rejection with elevated inflammation and risk for depression”
From From stress to inflammation and major depressive disorder: A social signal transduction theory of depression. (2014) · cites this paper as Slavich, O'Donovan, et al., 2010
The cited source says what the claim attributes to it.
In the citing paper
“this theory specifies that situations involving social threat are represented neurally by brain regions such as the anterior insula and dACC, which process experiences of negative affect and rejection-related distress”
From From stress to inflammation and major depressive disorder: A social signal transduction theory of depression. (2014) · cites this paper as Slavich, O'Donovan, et al., 2010
The cited source says what the claim attributes to it.
In the citing paper
“Most center around the notion that stress triggers the release of pro-inflammatory cytokines, which access the central nervous system, eliciting neurobehavioral adjustments that manifest as depressive symptoms (3–5).”
From Clustering of depression and inflammation in adolescents previously exposed to childhood adversity (2012) · cites this paper as [5]
In the citing paper
“Social rejection is one of the strongest proximal risk factors for depression (Slavich et al., 2010)”
From Social functioning in major depressive disorder (2016) · cites this paper as Slavich et al., 2010
In the citing paper
“Recently, a polymorphism in the MOR gene has been found to influence neural and psychological responses to rejection, likely by affecting opioid receptor expression and signalling efficiency (Slavich et al., 2010).”
From Social functioning in major depressive disorder (2016) · cites this paper as Slavich et al., 2010
In the citing paper
“Insufficient validation may then trigger consequences of this need threat, such as negative affect (e.g., feeling distressed, sad, anxious, or embarrassed), and negative self-relevant cognitions (viewing oneself as less worthy, or less likable), which are known risk factors for depression (Hankin & Abramson, 2001; Masten et al., 2011; Slavich, O’Donovan, Epel, & Kemeny, 2010).”
From Getting Fewer “Likes” Than Others on Social Media Elicits Emotional Distress Among Victimized Adolescents (2020) · cites this paper as Slavich, O’Donovan, Epel, & Kemeny, 2010
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The need to belong: Desire for interpersonal attachments as a fundamental human motivation.
Baumeister, R. F., & Leary, M. R. (1995) · Psychological Bulletin · doi:10.1037//0033-2909.117.3.497 · Cited by 23,245
(1969) · Cited by 18,340
The Standard Edition of the Complete Psychological Works of Sigmund Freud
Freud, S. (1953) · Cited by 17,730
Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene
Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., et al. (2003) · Science · doi:10.1126/science.1083968 · Cited by 8,120
Sapolsky, R. M., Romero, L. M., & Munck, A. U. (2000) · Endocrine Reviews · doi:10.1210/edrv.21.1.0389 · Cited by 7,541
Sapolsky, R. M. (2000) · Endocrine Reviews · doi:10.1210/er.21.1.55 · Cited by 7,533
From inflammation to sickness and depression: when the immune system subjugates the brain
Dantzer, R., O'Connor, J. C., Freund, G. G., Johnson, R. W., & Kelley, K. W. (2008) · Nature Reviews Neuroscience · doi:10.1038/nrn2297 · Cited by 7,395
Effects of stress throughout the lifespan on the brain, behaviour and cognition
Lupien, S. J., McEwen, B. S., Gunnar, M. R., & Heim, C. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2639 · Cited by 6,256
Dickerson, S. S., & Kemeny, M. E. (2004) · Psychological Bulletin · doi:10.1037/0033-2909.130.3.355 · Cited by 5,881
Self-citationFreud, S. (1922) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-192211000-00066 · Cited by 5,444
Depression. Clinical, Experimental, and Theoretical Aspects.
(1968) · Annals of Internal Medicine · doi:10.7326/0003-4819-68-2-502 · Cited by 5,233
Selye, H. (1956) · Medical Entomology and Zoology · Cited by 5,224
Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression
Miller, A. H., Maletic, V., & Raison, C. L. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.11.029 · Cited by 3,848
Structure and function of telomeres
Blackburn, E. H. (1991) · Nature · doi:10.1038/350569a0 · Cited by 3,596
Social Origins of Depression: A Study of Psychiatric Disorder in Women.
Schnitzer, P. K., Brown, G. W., & Harris, T. (1980) · Contemporary Sociology A Journal of Reviews · doi:10.2307/2065631 · Cited by 3,053
Cytokines sing the blues: inflammation and the pathogenesis of depression
Raison, C. L., Capuron, L., & Miller, A. H. (2006) · Trends in Immunology · doi:10.1016/j.it.2005.11.006 · Cited by 3,009
Accelerated telomere shortening in response to life stress
Epel, E. S., Blackburn, E. H., Lin, J., Dhabhar, F. S., Adler, N. E., Morrow, J. D., & Cawthon, R. M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0407162101 · Cited by 3,002
Self-citationHammen, C. (2005) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.1.102803.143938 · Cited by 2,979
Attachment and Loss: Vol.3: Loss : Sadness and Depression
Bowlby, J. (1980) · Cited by 2,650
Elenkov, I. J., Wilder, R. L., Chrousos, G. P., & Vizi, E. S. (2000) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01470-4 · Cited by 2,252
Heim, C. (2000) · JAMA · doi:10.1001/jama.284.5.592 · Cited by 1,968
Social Origins of Depression: A Study of Psychiatric Disorder in Women
McDaniel, E. G. (1980) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-198009000-00013 · Cited by 1,894
Transduction of psychosocial stress into the neurobiology of recurrent affective disorder
(1992) · American Journal of Psychiatry · doi:10.1176/ajp.149.8.999 · Cited by 1,848
Risch, N., Herrell, R., Lehner, T., Liang, K.-Y., Eaves, L., Hoh, J., Griem, A., Kovacs, M., Ott, J., & Merikangas, K. R. (2009) · JAMA · doi:10.1001/jama.2009.878 · Cited by 1,655
The Evolution of the Cognitive Model of Depression and Its Neurobiological Correlates
Beck, A. T. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.08050721 · Cited by 1,537
Depression: Clinical, Experimental, and Theoretical Aspects
Friedman, S. (1968) · JAMA · doi:10.1001/jama.1968.03140130056023 · Cited by 1,125
Stressful life events, genetic liability, and onset of an episode of major depression in women
(1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.6.833 · Cited by 1,063
How stress influences the immune response
Padgett, D. A., & Glaser, R. (2003) · Trends in Immunology · doi:10.1016/s1471-4906(03)00173-x · Cited by 1,059
Gotlib, I. H., & Hammen, C. L. (2002) · Cited by 980
Kendler, K. S., Hettema, J. M., Butera, F., Gardner, C. O., & Prescott, C. A. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.8.789 · Cited by 966
A mechanism converting psychosocial stress into mononuclear cell activation
Bierhaus, A., Wolf, J., Andrassy, M., Rohleder, N., Humpert, P. M., Petrov, D., Ferstl, R., von Eynatten, M., Wendt, T., Rudofsky, G., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0438019100 · Cited by 927
Serotonin Transporter (5-HTTLPR) Genotype and Amygdala Activation: A Meta-Analysis
Munafò, M. R., Brown, S. M., & Hariri, A. R. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.08.016 · Cited by 789
Harrison, N. A., Brydon, L., Walker, C., Gray, M. A., Steptoe, A., & Critchley, H. D. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.03.015 · Cited by 756
Social regulation of gene expression in human leukocytes
Cole, S. W., Hawkley, L. C., Arevalo, J. M., Sung, C. Y., Rose, R. M., & Cacioppo, J. T. (2007) · Genome Biology · doi:10.1186/gb-2007-8-9-r189 · Cited by 745 · cited 2×
“Finally, there is evidence that aspects of social rejection, specifically social isolation (Cole et al., 2007) and interpersonal stress (Miller et al.”
Elevated inflammation levels in depressed adults with a history of childhood maltreatment
Danese, A., Moffitt, T. E., Pariante, C. M., Ambler, A., Poulton, R., & Caspi, A. (2008) · Archives of General Psychiatry · doi:10.1001/archpsyc.65.4.409 · Cited by 641 · cited 1×
“Early maltreatment also predicts elevations in inflammation in adulthood (Danese et al., 2008).”
Depression and immune function
Kiecolt-Glaser, J. K., & Glaser, R. (2002) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(02)00309-4 · Cited by 571
Cytokines and psychopathology: Lessons from interferon-α
Capuron, L., & Miller, A. H. (2004) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.02.009 · Cited by 562
HPA Axis Reactivity: A Mechanism Underlying the Associations Among 5-HTTLPR, Stress, and Depression
Gotlib, I. H., Joormann, J., Minor, K. L., & Hallmayer, J. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.10.008 · Cited by 558
Monroe, S. M., Rohde, P., Seeley, J. R., & Lewinsohn, P. M. (1999) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.108.4.606 · Cited by 546
Kessler, R. C., Birnbaum, H., Bromet, E., Hwang, I., Sampson, N., & Shahly, V. (2010) · Psychological Medicine · doi:10.1017/s0033291709990213 · Cited by 542
Life stressors as risk factors in depression.
Mazure, C. M. (1998) · Clinical Psychology: Science and Practice · doi:10.1111/j.1468-2850.1998.tb00151.x · Cited by 535
Kemeny, M. E. (2003) · Current Directions in Psychological Science · doi:10.1111/1467-8721.01246 · Cited by 519
Self-citationSimon, N. M., Smoller, J. W., McNamara, K. L., Maser, R. S., Zalta, A. K., Pollack, M. H., Nierenberg, A. A., Fava, M., & Wong, K.-K. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.02.004 · Cited by 516
Acute Threat to the Social Self: Shame, Social Self-esteem, and Cortisol Activity
Gruenewald, T. L., Kemeny, M. E., Aziz, N., & Fahey, J. L. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000143639.61693.ef · Cited by 515
Self-citationDepression: The Evolution of Powerlessness
Gilbert, P. (1992) · Medical Entomology and Zoology · Cited by 492
Uher, R., & McGuffin, P. (2010) · Molecular Psychiatry · doi:10.1038/mp.2009.123 · Cited by 424
Elenkov, I. J., Papanicolaou, D. A., Wilder, R. L., & Chrousos, G. P. (1996) · PubMed · Cited by 419
Damjanovic, A. K., Yang, Y., Glaser, R., Kiecolt‐Glaser, J. K., Nguyen, H., Laskowski, B. F., Zou, Y., Beversdorf, D. Q., & Weng, N. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.6.4249 · Cited by 413
Experiences of depression: theoretical, clinical, and research perspectives
(2004) · Choice Reviews Online · doi:10.5860/choice.42-0613 · Cited by 384
Reduced telomerase activity in human T lymphocytes exposed to cortisol
Choi, J., Fauce, S. R., & Effros, R. B. (2008) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.12.004 · Cited by 352
Mendes, W. B., Major, B., McCoy, S., & Blascovich, J. (2008) · Journal of Personality and Social Psychology · doi:10.1037/0022-3514.94.2.278 · Cited by 346
Denson, T. F., Spanovic, M., & Miller, N. (2009) · Psychological Bulletin · doi:10.1037/a0016909 · Cited by 328
Social stress induces glucocorticoid resistance in subordinate animals
Avitsur, R., Stark, J. L., & Sheridan, J. F. (2001) · Hormones and Behavior · doi:10.1006/hbeh.2001.1653 · Cited by 321
Pains and Pleasures of Social Life
Lieberman, M. D., & Eisenberger, N. I. (2009) · Science · doi:10.1126/science.1170008 · Cited by 320
Depression: the evolution of powerlessness
(1992) · Choice Reviews Online · doi:10.5860/choice.30-1785 · Cited by 318
An fMRI study of cytokine-induced depressed mood and social pain: The role of sex differences
Eisenberger, N. I., Inagaki, T. K., Rameson, L. T., Mashal, N. M., & Irwin, M. R. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.04.040 · Cited by 313
The effects of social status on biological aging as measured by white‐blood‐cell telomere length
Cherkas, L. F., Aviv, A., Valdes, A. M., Hunkin, J., Gardner, J. P., Surdulescu, G. L., Kimura, M., & Spector, T. D. (2006) · Aging Cell · doi:10.1111/j.1474-9726.2006.00222.x · Cited by 306
Social stress induces glucocorticoid resistance in macrophages
Stark, J. L., Avitsur, R., Padgett, D. A., Campbell, K. A., Beck, F. M., & Sheridan, J. F. (2001) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2001.280.6.r1799 · Cited by 295
Perturbing the organism: the biology of stressful experience
(1993) · Choice Reviews Online · doi:10.5860/choice.30-2669 · Cited by 285
Illness, Cytokines, and Depression
YIRMIYA, R., POLLAK, Y., MORAG, M., REICHENBERG, A., BARAK, O., AVITSUR, R., SHAVIT, Y., OVADIA, H., WEIDENFELD, J., MORAG, A., et al. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb05412.x · Cited by 284
Harkness, K. L., Bruce, A. E., & Lumley, M. N. (2006) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.115.4.730 · Cited by 272
Immunological effects of induced shame and guilt
Dickerson, S. S., Kemeny, M. E., Aziz, N., Kim, K. H., & Fahey, J. L. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000097338.75454.29 · Cited by 245
Self-citationGlaser, R., Robles, T. F., Sheridan, J. F., Malarkey, W. B., & Kiecolt‐Glaser, J. K. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.10.1009 · Cited by 242
Anterior Cingulate Activation and Error Processing During Interferon-Alpha Treatment
Capuron, L., Pagnoni, G., Demetrashvili, M., Woolwine, B. J., Nemeroff, C. B., Berns, G. S., & Miller, A. H. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.03.033 · Cited by 222
Dickerson, S. S., Gable, S. L., Irwin, M. R., Aziz, N., & Kemeny, M. E. (2009) · Psychological Science · doi:10.1111/j.1467-9280.2009.02437.x · Cited by 197
Self-citationMiller, G. E., Rohleder, N., & Cole, S. W. (2009) · Psychosomatic Medicine · doi:10.1097/psy.0b013e318190d7de · Cited by 197
5-HTTLPR Biases Amygdala Activity in Response to Masked Facial Expressions in Major Depression
Dannlowski, U., Ohrmann, P., Bauer, J., Deckert, J., Hohoff, C., Kugel, H., Arolt, V., Heindel, W. L., Kersting, A., Baune, B. T., et al. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301411 · Cited by 179
Telomere Length, Current Perceived Stress, and Urinary Stress Hormones in Women
Parks, C. G., Miller, D. B., McCanlies, E. C., Cawthon, R., Andrew, M. E., DeRoo, L. A., & Sandler, D. P. (2009) · Cancer Epidemiology Biomarkers & Prevention · doi:10.1158/1055-9965.epi-08-0614 · Cited by 176
Gene-Environment Interactions in Depression Research
Monroe, S. M., & Reid, M. W. (2008) · Psychological Science · doi:10.1111/j.1467-9280.2008.02181.x · Cited by 170
Characterizing life events as risk factors for depression: The role of fateful loss events.
Shrout, P. E., Link, B. G., Dohrenwend, B. P., Skodol, A. E., Stueve, A., & Mirotznik, J. (1989) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.98.4.460 · Cited by 167
O’Donovan, A., Lin, J., Dhabhar, F. S., Wolkowitz, O., Tillie, J. M., Blackburn, E., & Epel, E. (2009) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2008.11.006 · Cited by 161
Self-citationTargeted Rejection Predicts Hastened Onset of Major Depression
Slavich, G. M., Thornton, T., Torres, L. D., Monroe, S. M., & Gotlib, I. H. (2009) · Journal of Social and Clinical Psychology · doi:10.1521/jscp.2009.28.2.223 · Cited by 154
Self-citationKemeny, M. E. (2009) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2008.08.008 · Cited by 138
Self-citationBogoch, S. (1969) · Springer eBooks · doi:10.1007/978-1-4899-6323-9_29 · Cited by 128
The psychobiology of trait shame in young women: Extending the social self preservation theory.
Rohleder, N., Chen, E., Wolf, J. M., & Miller, G. E. (2008) · Health Psychology · doi:10.1037/0278-6133.27.5.523 · Cited by 124
When grief heats up: Pro-inflammatory cytokines predict regional brain activation
O'Connor, M.-F., Irwin, M. R., & Wellisch, D. K. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.05.049 · Cited by 123
Slavich, G. M., Monroe, S. M., & Gotlib, I. H. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.03.004 · Cited by 122
Self-citationMonroe, S. M., Slavich, G. M., Torres, L. D., & Gotlib, I. H. (2007) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.116.1.116 · Cited by 122
Self-citationGene-Environment Interactions: Biologically Valid Pathway or Artifact?
Rutter, M., Thapar, A., & Pickles, A. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.167 · Cited by 115
Dagarag, M. D., Evazyan, T., Rao, N. P., & Effros, R. B. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.10.6303 · Cited by 107
Wirtz, P. H., von Känel, R., Mohiyeddini, C., Emini, L., Rüdisüli, K., Groessbauer, S., & Ehlert, U. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-2586 · Cited by 98
Perturbing the organism: The biology of stressful experience
Huxtable, R. J. (1992) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(92)90103-d · Cited by 56
Severe life events predict specific patterns of change in cognitive biases in major depression
Monroe, S. M., Slavich, G. M., Torres, L. D., & Gotlib, I. H. (2007) · Psychological Medicine · doi:10.1017/s0033291707000281 · Cited by 53
Self-citationAccess to Social Support in Life and in the Laboratory
O’Donovan, A., & Hughes, B. M. (2008) · Journal of Health Psychology · doi:10.1177/1359105308095968 · Cited by 38
Self-citationDepression and early adverse experiences.
Goodman, S. H., & Brand, S. R. (2009) · Cited by 34
Final considerations and future directions
WALTERS, P. A. (2009) · Cambridge University Press eBooks · doi:10.1017/cbo9780511575204.005 · Cited by 1
Flagged first, then by citations
3 of the 89 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Slavich, G. M., & Irwin, M. R. (2014) · Psychological Bulletin · doi:10.1037/a0035302 · Cited by 2,206
Self-citationMarital quality and health: A meta-analytic review.
Robles, T. F., Slatcher, R. B., Trombello, J. M., & McGinn, M. M. (2013) · Psychological Bulletin · doi:10.1037/a0031859 · Cited by 1,764
So depression is an inflammatory disease, but where does the inflammation come from?
Berk, M., Williams, L. J., Jacka, F. N., O’Neil, A., Pasco, J. A., Moylan, S., Allen, N. B., Stuart, A. L., Hayley, A. C., Byrne, M. L., et al. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-200 · Cited by 1,423
More than a feeling: A unified view of stress measurement for population science
Epel, E. S., Crosswell, A. D., Mayer, S. E., Prather, A. A., Slavich, G. M., Puterman, E., & Mendes, W. B. (2018) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2018.03.001 · Cited by 1,077
Self-citationEisenberger, N. I. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3231 · Cited by 1,016
Metadata
- Authors
- Slavich, G. M., O’Donovan, A., Epel, E. S., & Kemeny, M. E.
- Affiliations
- University of California, San Francisco (US)
- Corresponding author
- Slavich, George M.
- Venue
- Neuroscience & Biobehavioral Reviews
- Publisher
- Elsevier BV
- Published
- 2010-09
- Volume
- 35
- Issue
- 1
- Pages
- 39-45
- ISSN
- 0149-7634 (ISSN-L)
- PMC
- PMC2926175
- OpenAlex
- W2089060681
- Cited by
- 362
- References
- 89
- Citations by year
- 2026: 15 · 2025: 16 · 2024: 37 · 2023: 30 · 2022: 35 · 2021: 28 · 2020: 34 · 2019: 18 · 2018: 20 · 2017: 22 · 2016: 27 · 2015: 18 · 2014: 13 · 2013: 16 · 2012: 20
- FWCI
- 1.35
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Neuroscience & Biobehavioral Reviews (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Institute of Mental Health (T32MH019391)
- Topics
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
- Social Sciences › Psychology › Social Psychology › Death Anxiety and Social Exclusion
- Keywords
- social rejection, depression, psychobiological model, self-conscious emotions, shame, anterior insula, dorsal anterior cingulate cortex, hypothalamic-pituitary-adrenal axis, sympathoadrenal system, inflammatory cytokines, sickness behavior, glucocorticoid resistance, immunosenescence
- MeSH terms
- Animals, Depression, Humans, Rejection, Psychology, Stress, Psychological
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
