Inhibition of mitochondrial respiratory chain in brain of rats subjected to an experimental model of depression

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 315,771 · see citing works

Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the “phosphocreatine circuit” for cellular energy homeostasis

Wallimann, T., Wyss, M., Brdiczka, D., Nicolay, K., & Eppenberger, H. M. (1992) · Biochemical Journal · doi:10.1042/bj2810021 · Cited by 2,011 · see citing works

Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant

Willner, P., Towell, A., Sampson, D., Sophokleous, S., & Muscat, R. (1987) · Psychopharmacology · doi:10.1007/bf00187257 · Cited by 1,993 · see citing works

Biochemical and molecular investigations in respiratory chain deficiencies

Rustin, P., Chrétien, D., Bourgeron, T., Gérard, B., Rötig, A., Saudubray, J., & Münnich, A. (1994) · Clinica Chimica Acta · doi:10.1016/0009-8981(94)90055-8 · Cited by 1,239 · see citing works

Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress

Prabakaran, S., SWATTON, J. E., Ryan, M. M., Huffaker, S. J., Huang, J.-J., Griffin, J. L., Wayland, M. T., Freeman, T., Dudbridge, F., Lilley, K. S., et al. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001511 · Cited by 973 · see citing works

THE CREATINE-CREATINE PHOSPHATE ENERGY SHUTTLE

Bessman, S. P., & Carpenter, C. L. (1985) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.54.070185.004151 · Cited by 759 · see citing works

Differential Inhibitory Action of Nitric Oxide and Peroxynitrite on Mitochondrial Electron Transport

Cassina, A., & Radí, R. (1996) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1996.0178 · Cited by 725 · see citing works

The mitochondrial energy transduction system and the aging process

Navarro, A., & Boveris, A. (2007) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00213.2006 · Cited by 646 · see citing works

A method for the estimation of serum creatine kinase and its use in comparing creatine kinase and aldolase activity in normal and pathological sera

Hughes, B. P. (1962) · Clinica Chimica Acta · doi:10.1016/0009-8981(62)90137-7 · Cited by 550 · see citing works

An animal model of anhedonia: attenuation of sucrose consumption and place preference conditioning by chronic unpredictable mild stress

Papp, M., Willner, P., & Muscat, R. (1991) · Psychopharmacology · doi:10.1007/bf02244188 · Cited by 542 · see citing works

Neuroimaging studies of the cerebellum: language, learning and memory

Desmond, J. E., & Fiez, J. A. (1998) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(98)01211-x · Cited by 507 · see citing works

Animal model of depression: Pharmacological sensitivity of a hedonic deficit

Katz, R. J. (1982) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(82)90053-3 · Cited by 480 · see citing works

Nitric oxide, mitochondria and neurological disease

Heales, S., Bolaños, J. P., Stewart, V. C., Brookes, P. S., Land, J. M., & Clark, J. B. (1999) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/s0005-2728(98)00168-6 · Cited by 476 · see citing works

Differential investigation of the capacity of succinate oxidation in human skeletal muscle

Fischer, J., Ruitenbeek, W., BERDEN, J. A., Trijbels, J. M. F., Veerkamp, J. H., Stadhouders, A. M., Sengers, R. C. A., & Janssen, A. J. M. (1985) · Clinica Chimica Acta · doi:10.1016/0009-8981(85)90135-4 · Cited by 471 · see citing works

Production of Reactive Oxygen Species in Brain Mitochondria: Contribution by Electron Transport Chain and Non–Electron Transport Chain Sources

Adam-Vizi, V. (2005) · Antioxidants & Redox Signaling · doi:10.1089/ars.2005.7.1140 · Cited by 439 · see citing works

Endophenotypes in the Genetic Analyses of Mental Disorders

Cannon, T. D., & Keller, M. C. (2006) · Annual Review of Clinical Psychology · doi:10.1146/annurev.clinpsy.2.022305.095232 · Cited by 399 · see citing works

Glutathione Depletion, Lipid Peroxidation and Mitochondrial Dysfunction Are Induced by Chronic Stress in Rat Brain

Madrigal, J. L. M. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00208-6 · Cited by 381 · see citing works

Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress

Prabakaran, S., SWATTON, J. E., Ryan, M. M., Huffaker, S. J., Huang, J. T.-J., Griffin, J. L., Wayland, M. T., Freeman, T., Dudbridge, F., Lilley, K. S., et al. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001532 · Cited by 375 · see citing works

Volumetric neuroimaging investigations in mood disorders: bipolar disorder versus major depressive disorder

Konarski, J. Z., McIntyre, R. S., Kennedy, S. H., Rafi‐Tari, S., Soczynska, J. K., & Ketter, T. A. (2008) · Bipolar Disorders · doi:10.1111/j.1399-5618.2008.00435.x · Cited by 297 · see citing works

Oxidative Modification of Creatine Kinase BB in Alzheimer’s Disease Brain

Aksenov, M. Y., Aksenova, M. V., Butterfield, D. A., & Markesbery, W. R. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0742520.x · Cited by 286 · see citing works

Alterations of mitochondrial function and correlations with personality traits in selected major depressive disorder patients

Gardner, A. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(02)00067-8 · Cited by 272 · see citing works

Regional Mitochondrial Respiratory Activity in Huntington's Disease Brain

Brennan, W. A., Bird, E. D., & Aprille, J. R. (1985) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1985.tb07192.x · Cited by 265 · see citing works

The cerebellum on the rise in human emotion

Schutter, D. J. L. G., & Van Honk, J. (2005) · The Cerebellum · doi:10.1080/14734220500348584 · Cited by 261 · see citing works

The Molecular Neurobiology of Depression

Shelton, R. C. (2007) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2006.12.005 · Cited by 242 · see citing works

Reversal of stress-induced anhedonia by the atypical antidepressants, fluoxetine and maprotiline

Muscat, R., Papp, M., & Willner, P. (1992) · Psychopharmacology · doi:10.1007/bf02247719 · Cited by 237 · see citing works

Is the cerebellum relevant in the circuitry of neuropsychiatric disorders?

Konarski, J. Z., McIntyre, R. S., Grupp, L. A., & Kennedy, S. H. (2005) · Journal of Psychiatry and Neuroscience · doi:10.1139/jpn.0526 · Cited by 224 · see citing works

Supramolecular Structure of the Mitochondrial Oxidative Phosphorylation System

Boekema, E. J., & Braun, H. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.r600031200 · Cited by 224 · see citing works

Review of the Literature on Major Mental Disorders in Adult Patients With Mitochondrial Diseases

Fattal, O., Budur, K., Vaughan, A. J., & Franco, K. (2006) · Psychosomatics · doi:10.1176/appi.psy.47.1.1 · Cited by 209 · see citing works

Nitric oxide inhibits creatine kinase and regulates rat heart contractile reserve.

Gross, W. L., Bak, M. I., Ingwall, J. S., Arstall, M. A., Smith, T. W., Balligand, J., & Kelly, R. A. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.11.5604 · Cited by 199 · see citing works

Repeated Restraint Stress Induces Oxidative Damage in Rat Hippocampus

Fontella, F. U., Siqueira, I. R., de Vasconcellos, A. P. S., Tabajara, Â. S., Netto, C. A., & Dalmaz, C. (2005) · Neurochemical Research · doi:10.1007/s11064-004-9691-6 · Cited by 195 · see citing works

Effects of chronic variate stress on feeding behavior and on monoamine levels in different rat brain structures

Gamaro, G. D. (2002) · Neurochemistry International · doi:10.1016/s0197-0186(02)00080-3 · Cited by 195 · see citing works

Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes

Moreira, P. I., Santos, M. S., Seiça, R. M. F., & Oliveira, C. R. (2007) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2007.01.017 · Cited by 190 · see citing works

Mitochondrial dysfunction in rat brain with agingInvolvement of complex I, reactive oxygen species and cardiolipin

Petrosillo, G., Matera, M. G., Casanova, G., Ruggiero, F. M., & Paradies, G. (2008) · Neurochemistry International · doi:10.1016/j.neuint.2008.07.001 · Cited by 172 · see citing works

Evidence for Decreased DARPP-32 in the Prefrontal Cortex of Patients With Schizophrenia

Albert, K. A., Hemmings, H. C., Adamo, A. I. B., Potkin, S. G., Akbarian, S., Sandman, C. A., Cotman, C. W., Bunney, W. E., & Greengard, P. (2002) · Archives of General Psychiatry · doi:10.1001/archpsyc.59.8.705 · Cited by 168 · see citing works

Neuroendocrinological mechanisms of actions of antidepressant drugs

Schüle, C. (2007) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01516.x · Cited by 167 · see citing works

Brain metabolism and brain disease: Is metabolic deficiency the proximate cause of Alzheimer dementia?

Blass, J. P. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.10087 · Cited by 162 · see citing works

Alzheimer's Disease: A Lesson from Mitochondrial Dysfunction

Moreira, P. I., Santos, M. S., & Oliveira, C. R. (2007) · Antioxidants and Redox Signaling · doi:10.1089/ars.2007.1703 · Cited by 150 · see citing works

Effect of Restraint Stress on Feeding Behavior of Rats

Ely, D. R., Dapper, V. D., Marasca, J. A., Correa, J. B. B., Gamaro, G. D., Xavier, M., Michalowski, M. B., Catelli, D. H., Rosat, R. M., & Ferreira, M. B. C. (1997) · Physiology & Behavior · doi:10.1016/s0031-9384(96)00450-7 · Cited by 143 · see citing works

Abnormal properties of creatine kinase in Alzheimer's disease brain: Correlation of reduced enzyme activity and active site photolabeling with aberrant cytosol-membrane partitioning

David, S. S. M., Shoemaker, M. T., & Haley, B. E. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(97)00343-4 · Cited by 141 · see citing works

Chronic variable stress and partial 5-HT denervation by parachloroamphetamine treatment in the rat: Effects on behavior and monoamine neurochemistry

Harro, J., Tõnissaar, M., Eller, M., Kask, A., & Oreland, L. (2001) · Brain Research · doi:10.1016/s0006-8993(01)02256-9 · Cited by 124 · see citing works

Neural correlates of affective processing in response to sad and angry facial stimuli in patients with major depressive disorder

Lee, B.-T., Seok, J.-H., Lee, B.-C., Cho, S. W., Yoon, B.-J., Lee, K.-U., Chae, J.-H., Choi, I.-G., & Ham, B.-J. (2008) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.12.009 · Cited by 123 · see citing works

Reduction of Hippocampal Na+, K+-ATPase Activity in Rats Subjected to an Experimental Model of Depression

Gamaro, G. D., STRECK, E. L., Matté, C., Prediger, M. E., Wyse, Â. T. D. S., & Dalmaz, C. (2003) · Neurochemical Research · doi:10.1023/a:1024988113978 · Cited by 113 · see citing works

Octamers of Mitochondrial Creatine Kinase Isoenzymes Differ in Stability and Membrane Binding

Schlattner, U., & Wallimann, T. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m001919200 · Cited by 113 · see citing works

Inhibition of the creatine kinase reaction decreases the contractile reserve of isolated rat hearts

Hamman, B. L., Bittl, J. A., Jacobus, W. E., Allen, P. D., Spencer, R. G. S., Tian, R., & Ingwall, J. S. (1995) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1995.269.3.h1030 · Cited by 109 · see citing works

Energy metabolism, stress hormones and neural recovery from cerebral ischemia/hypoxia

Schurr, A. (2002) · Neurochemistry International · doi:10.1016/s0197-0186(01)00142-5 · Cited by 86 · see citing works

Immunoelectron microscopic investigation of creatine kinase BB-isoenzyme after cerebral ischemia in gerbils

Tomimoto, H., Yamamoto, K., Homburger, H. A., & Yanagihara, T. (1993) · Acta Neuropathologica · doi:10.1007/bf00228579 · Cited by 79 · see citing works

Mitochondrial dysfunction in human pathologies

Monsalve, M. (2006) · Frontiers in bioscience · doi:10.2741/2132 · Cited by 75 · see citing works

Lipid peroxidation and total radical-trapping potential of the lungs of rats submitted to chronic and sub-chronic stress

Torres, R. L., Torres, I. L. D. S., Gamaro, G. D., Fontella, F. U., Silveira, P. P., Moreira, J. S. R., Lacerda, M., Amoretti, J. R., Rech, D. L., Dalmaz, C., et al. (2004) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2004000200004 · Cited by 69 · see citing works

Octamer Formation and Coupling of Cardiac Sarcomeric Mitochondrial Creatine Kinase Are Mediated by Charged N-terminal Residues

Khuchua, Z. A., Qin, W., Boero, J., Cheng, J. M., Payne, R. M., Saks, V. A., & Strauss, A. W. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.36.22990 · Cited by 68 · see citing works

Theory of active antidepressants: A nonsynaptic approach to the treatment of depression

Kiss, J. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.04.006 · Cited by 68 · see citing works

Chronic Lithium Treatment has Antioxidant Properties but does not Prevent Oxidative Damage Induced by Chronic Variate Stress

de Vasconcellos, A. P. S., Nieto, F., Crema, L. M., Diehl, L. A., de Almeida, L. M., Prediger, M. E., da Rocha, E. R., & Dalmaz, C. (2006) · Neurochemical Research · doi:10.1007/s11064-006-9139-2 · Cited by 63 · see citing works

The complex roles of neurosteroids in depression and anxiety disorders

Longone, P., Rupprecht, R., Manieri, G. A., Bernardi, G., Romeo, E., & Pasini, A. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.10.001 · Cited by 62 · see citing works

Brain creatine kinase activity in an animal model of mania

STRECK, E. L., Amboni, G., Scaini, G., Di‐Pietro, P. B., Rezin, G. T., Valvassori, S. S., da Luz, G., Kapczinski, F. P., & Quevedo, J. (2008) · Life Sciences · doi:10.1016/j.lfs.2007.11.026 · Cited by 59 · see citing works

Predictability of chronic intermittent stress: effects on sympathetic-adrenal medullary responses of laboratory rats

Konarska, M., Stewart, R. E., & McCarty, R. (1990) · Behavioral and Neural Biology · doi:10.1016/0163-1047(90)90458-i · Cited by 53 · see citing works

Inactivation of brain mitochondrial Lon protease by peroxynitrite precedes electron transport chain dysfunction

Stanyer, L., Jørgensen, W., Hori, O., Clark, J. B., & Heales, S. (2008) · Neurochemistry International · doi:10.1016/j.neuint.2008.06.004 · Cited by 51 · see citing works

The effect of bovine serum albumin on the membrane potential and reactive oxygen species generation in succinate-supported isolated brain mitochondria

Tretter, L., Mayer-Takacs, D., & Ádám‐Vizi, V. (2006) · Neurochemistry International · doi:10.1016/j.neuint.2006.07.010 · Cited by 48 · see citing works

Antidepressant-like effect of nicotinamide adenine dinucleotide in the forced swim test in rats

Rex, A., Schickert, R., & Fink, H. (2003) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2003.11.001 · Cited by 48 · see citing works

Crystallization of mitochondrial creatine kinase. Growing of large protein crystals and electron microscopic investigation of microcrystals consisting of octamers.

Schnyder, T., Winkler, H., Gross, H., Eppenberger, H. M., & Wallimann, T. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)67790-2 · Cited by 43 · see citing works

Acute and repeated restraint stress influences cellular damage in rat hippocampal slices exposed to oxygen and glucose deprivation

Fontella, F. U., Cimarosti, H., Crema, L. M., Thomazi, A. P., Leite, M. C., Salbego, C. G., Gonçalves, C. A., Wofchuk, S. T., Dalmaz, C., & Netto, C. A. (2005) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2005.02.026 · Cited by 42 · see citing works

Effects of chronic variable stress and antidepressant drugs on behavioral inactivity during an uncontrollable stress: Interaction between both treatments

Murua, V. S., & Molina, V. A. (1992) · Behavioral and Neural Biology · doi:10.1016/0163-1047(92)90790-b · Cited by 37 · see citing works

Effect of Chronic Stress and Mifepristone Treatment on Voltage‐Dependent Ca2+ Currents in Rat Hippocampal Dentate Gyrus

van Gemert, N. G., & Joëls, M. (2006) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2006.01472.x · Cited by 34 · see citing works

Changes in regional long-term oxidative metabolism induced by partial serotonergic denervation and chronic variable stress in rat brain

Kanarik, M., Matrov, D., Kõiv, K., Eller, M., Tõnissaar, M., & Harro, J. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.08.003 · Cited by 30 · see citing works

Decreased Creatine Kinase Activity Caused by Electroconvulsive Shock

Búrigo, M., Roza, C. A., Bassani, C., Feier, G., Dal‐Pizzol, F., Quevedo, J., & STRECK, E. L. (2006) · Neurochemical Research · doi:10.1007/s11064-006-9091-1 · Cited by 19 · see citing works

Impaired mitochondrial function in psychiatric disorders

Manji, H. K., Kato, T., Prospero, N. A. D., Ness, S. L., Beal, M. F., Krams, M., & Chen, G. (2012) · Nature reviews. Neuroscience · doi:10.1038/nrn3229 · Cited by 478 · see citing works

NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder

Alcocer-Gómez, E., de Miguel, M., Casas-Barquero, N., Núñez-Vasco, J., Sánchez-Alcazar, J. A., Fernández-Rodríguez, A., & Cordero, M. D. (2014) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2013.10.017 · Cited by 443 · see citing works

Mitochondrial Dysfunction and Psychiatric Disorders

Rezin, G. T., Amboni, G., Zugno, A. I., Quevedo, J., & STRECK, E. L. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9865-8 · Cited by 443 · see citing works

Mitochondrial allostatic load puts the 'gluc' back in glucocorticoids

Picard, M., Juster, R.-P., & McEwen, B. S. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2014.22 · Cited by 405 · see citing works

Mitochondrial Dysfunction in Depression

Bansal, Y., & Kuhad, A. (2016) · Current Neuropharmacology · doi:10.2174/1570159x14666160229114755 · Cited by 355 · see citing works

Mitochondria and Mood: Mitochondrial Dysfunction as a Key Player in the Manifestation of Depression

Allen, J., Romay-Tallón, R., Brymer, K. J., Caruncho, H. J., & Kalynchuk, L. E. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00386 · Cited by 350 · see citing works

Psychological Stress and Mitochondria: A Systematic Review

Picard, M. A., & McEwen, B. S. (2018) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000545 · Cited by 339 · see citing works

The interplay between inflammation, oxidative stress, DNA damage, DNA repair and mitochondrial dysfunction in depression

Czarny, P., Wigner, P., Galecki, P., & Sliwinski, T. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.06.036 · Cited by 310 · see citing works

Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epidemiology, mechanisms and management

Berk, M., Köhler‐Forsberg, O., Turner, M., Penninx, B. W. J. H., Wrobel, A., Firth, J., Loughman, A., Reavley, N. J., McGrath, J. J., Momen, N. C., et al. (2023) · World Psychiatry · doi:10.1002/wps.21110 · Cited by 336 · see citing works

Mitochondrial respiration in peripheral blood mononuclear cells correlates with depressive subsymptoms and severity of major depression

Karabatsiakis, A., Böck, C., Salinas-Manrique, J., Kolassa, S., Calzia, E., Dietrich, D. E., & Kolassa, I. (2014) · Translational Psychiatry · doi:10.1038/tp.2014.44 · Cited by 237 · see citing works

The Neurobiology of Depression: an Integrated Overview from Biological Theories to Clinical Evidence

Ferrari, F., & Villa, R. F. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0032-y · Cited by 186 · see citing works

Stress and corticosteroids regulate rat hippocampal mitochondrial DNA gene expression via the glucocorticoid receptor

Hunter, R. G., Seligsohn, M., Rubin, T. G., Griffiths, B. B., Ozdemir, Y., Pfaff, D. W., Datson, N. A., & McEwen, B. S. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1602185113 · Cited by 174 · see citing works

Stress-induced biological aging: A review and guide for research priorities

Polsky, L. R., Rentscher, K. E., & Carroll, J. (2022) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2022.05.016 · Cited by 181 · see citing works

The Energy Metabolism Dysfunction in Psychiatric Disorders Postmortem Brains: Focus on Proteomic Evidence

Zuccoli, G. S., Saia-Cereda, V. M., Nascimento, J. M., & Martins-de-Souza, D. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00493 · Cited by 157 · see citing works

The Role of Nutrients in Protecting Mitochondrial Function and Neurotransmitter Signaling: Implications for the Treatment of Depression, PTSD, and Suicidal Behaviors

Du, J., Zhu, M. F., Bao, H., Bai, L., Dong, Y., Xiao, C., Zhang, G. Y., Henter, I. D., Rudorfer, M. V., & Vitiello, B. (2014) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2013.876960 · Cited by 164 · see citing works

A mitochondrial bioenergetic basis of depression

Klinedinst, N. J., & Regenold, W. T. (2014) · Journal of Bioenergetics and Biomembranes · doi:10.1007/s10863-014-9584-6 · Cited by 153 · see citing works

Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation

Yang, L., Youngblood, H. A., Wu, C., & Zhang, Q. (2020) · Translational Neurodegeneration · doi:10.1186/s40035-020-00197-z · Cited by 143 · see citing works

Nrf2: An all-rounder in depression

Zuo, C., Cao, H., Song, Y., Gu, Z., Huang, Y., Yang, Y., Miao, J., Zhu, L., Chen, J., Jiang, Y., et al. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102522 · Cited by 138 · see citing works

Anti-Inflammatory, Antioxidant, and Neuroprotective Effects of Polyphenols—Polyphenols as an Element of Diet Therapy in Depressive Disorders

Winiarska‐Mieczan, A., Kwiecień, M., Jachimowicz-Rogowska, K., Donaldson, J., Tomaszewska, E., & Baranowska‐Wójcik, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24032258 · Cited by 136 · see citing works

Potential toxic effects of iron oxide nanoparticles in in vivo and in vitro experiments

Szalay, B., Tátrai, E., Nyírő, G., Vezér, T., & Dura, G. (2011) · Journal of Applied Toxicology · doi:10.1002/jat.1779 · Cited by 130 · see citing works

Corticosterone reduces brain mitochondrial function and expression of mitofusin, BDNF in depression-like rodents regardless of exercise preconditioning.

Liu, W.-N., & Zhou, C.-L. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.12.003 · Cited by 126 · see citing works

Structural and Ultrastructural Analysis of Cerebral Cortex, Cerebellum, and Hypothalamus from Diabetic Rats

Hernández-Fonseca, J. P., Rincon, J. C., Pedreáñez, A. B., Viera, N., Arcaya, J. L., Carrizo, E., & Mosquera, J. (2009) · Experimental Diabetes Research · doi:10.1155/2009/329632 · Cited by 123 · see citing works

Mitochondria and the economy of stress (mal)adaptation

Morava, É., & Kozicz, T. (2013) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.02.005 · Cited by 119 · see citing works

Changes in mitochondrial function are pivotal in neurodegenerative and psychiatric disorders: How important is BDNF ?

Markham, A., Bains, R. S., Franklin, P., & Spedding, M. (2013) · British Journal of Pharmacology · doi:10.1111/bph.12531 · Cited by 113 · see citing works

Mitochondrial respiratory chain in the colonic mucosal of patients with ulcerative colitis

Sifroni, K. G., Damiani, C. R., Stoffel, C., Cardoso, M. R., Ferreira, G. K., Jeremias, I. C., Rezin, G. T., Scaini, G., Schuck, P. F., Dal‐Pizzol, F., et al. (2010) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-010-0474-x · Cited by 111 · see citing works

Increased plasma levels of circulating cell-free mitochondrial DNA in suicide attempters: associations with HPA-axis hyperactivity

Lindqvist, D., Fernström, J., Grudet, C., Ljunggren, L., Träskman-Bendz, L., Ohlsson, L., & Westrin, Å. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.236 · Cited by 111 · see citing works

Mitochondrial respiration in blood platelets of depressive patients

Hroudová, J., Fišar, Z., Kitzlerová, E., Zvěřová, M., & Raboch, J. (2013) · Mitochondrion · doi:10.1016/j.mito.2013.05.005 · Cited by 108 · see citing works

Mitochondrial transplantation attenuates lipopolysaccharide- induced depression-like behaviors

Wang, Y., Ni, J., Gao, C., Xie, L., Zhai, L., Cui, G., & Yin, X. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.04.010 · Cited by 107 · see citing works

Effects of exercise on mitochondrial function, neuroplasticity and anxio-depressive behavior of mice

Aguiar, A. S., Stragier, E., Scheffer, D. D. L., Remor, A. P., de Oliveira, P. A., Prediger, R. D., Latini, A., Raisman‐Vozari, R., Mongeau, R., & Lanfumey, L. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.04.027 · Cited by 105 · see citing works

Oxidative Stress at the Crossroads of Aging, Stroke and Depression

Shao, A., Lin, D., Wang, L., Tu, S., Lenahan, C., & Zhang, J. (2020) · Aging and Disease · doi:10.14336/ad.2020.0225 · Cited by 101 · see citing works

Coenzyme Q10 displays antidepressant-like activity with reduction of hippocampal oxidative/nitrosative DNA damage in chronically stressed rats

Aboul-Fotouh, S. (2013) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2012.12.027 · Cited by 97 · see citing works

Mitophagy in the basolateral amygdala mediates increased anxiety induced by aversive social experience

Duan, K., Gu, Q., Petralia, R. S., Wang, Y., Panja, D., Liu, X., Lehmann, M. L., Zhu, H., Zhu, J., & Li, Z. (2021) · Neuron · doi:10.1016/j.neuron.2021.09.008 · Cited by 95 · see citing works

Emerging roles of brain metabolism in cognitive impairment and neuropsychiatric disorders

Morella, I., Brambilla, R., & Morè, L. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104892 · Cited by 96 · see citing works

Combined Metabolomics and Proteomics Analysis of Major Depression in an Animal Model: Perturbed Energy Metabolism in the Chronic Mild Stressed Rat Cerebellum

Shao, W., Chen, J., Fan, S., Lei, Y., Xu, H., Zhou, J., Cheng, P.-F., Yang, Y., Rao, C.-L., Wu, B. C., et al. (2015) · OMICS A Journal of Integrative Biology · doi:10.1089/omi.2014.0164 · Cited by 93 · see citing works

Abnormal high-energy phosphate molecule metabolism during regional brain activation in patients with bipolar disorder

Yüksel, Ç., Du, F., Ravichandran, C. T., Goldbach, J. R., Thida, T., Lin, P., Dora, B., Gelda, J., O'Connor, L., Sehovic, S., et al. (2015) · Molecular Psychiatry · doi:10.1038/mp.2015.13 · Cited by 91 · see citing works

Protective effects of resveratrol on mitochondrial function in the hippocampus improves inflammation-induced depressive-like behavior

Chen, W., Du, J.-K., Hu, X., Yu, Q., Li, D., Wang, C.-N., Zhu, X., & Liu, Y. (2017) · Physiology & Behavior · doi:10.1016/j.physbeh.2017.09.024 · Cited by 91 · see citing works

Low-Level Laser Irradiation Improves Depression-Like Behaviors in Mice

Xu, Z., Guo, X., Yong, Y., Tucker, D., Lu, Y., Xin, N., Zhang, G., Yang, L., Li, J., Du, X., et al. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-9983-2 · Cited by 87 · see citing works

Socioeconomic Deprivation, Adverse Childhood Experiences and Medical Disorders in Adulthood: Mechanisms and Associations

Morris, G., Berk, M., Maes, M. H. J., Carvalho, A. F., & Puri, B. K. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-1498-1 · Cited by 87 · see citing works

Leukocyte mitochondrial DNA (mtDNA) content is associated with depression in old women

Kim, M.-Y., Lee, J., Kang, H., Kim, E., & Lee, D. (2010) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2010.11.019 · Cited by 82 · see citing works

Mitochondria and the central nervous system: searching for a pathophysiological basis of psychiatric disorders

STRECK, E. L., Gonçalves, C. L., Furlanetto, C. B., Scaini, G., Dal‐Pizzol, F., & Quevedo, J. (2014) · Brazilian Journal of Psychiatry · doi:10.1590/1516-4446-2013-1224 · Cited by 82 · see citing works

The potential of transcranial photobiomodulation therapy for treatment of major depressive disorder

Salehpour, F., & Rasta, S. H. (2017) · Reviews in the Neurosciences · doi:10.1515/revneuro-2016-0087 · Cited by 78 · see citing works

Stress and glucocorticoid receptor regulation of mitochondrial gene expression

Lapp, H. E., Bartlett, A. A., & Hunter, R. G. (2018) · Journal of Molecular Endocrinology · doi:10.1530/jme-18-0152 · Cited by 78 · see citing works

The cerebellum under stress

Moreno-Rius, J. (2019) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2019.100774 · Cited by 75 · see citing works

Depression-like behaviors are accompanied by disrupted mitochondrial energy metabolism in chronic corticosterone-induced mice

Xie, X., Shen, Q., Yu, C., Xiao, Q., Zhou, J., Xiong, Z., Li, Z., & Fu, Z. (2020) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2020.105607 · Cited by 73 · see citing works

Connecting Dots between Mitochondrial Dysfunction and Depression

Khan, M., Baussan, Y., & Hébert-Chatelain, É. (2023) · Biomolecules · doi:10.3390/biom13040695 · Cited by 77 · see citing works

Baicalin ameliorates CUMS-induced depression-like behaviors through activating AMPK/PGC-1α pathway and enhancing NIX-mediated mitophagy in mice

Jin, X., Zhu, L., Lu, S., Li, C., Bai, M., Xu, E., Shen, J.-D., & Li, Y. (2022) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2022.175435 · Cited by 71 · see citing works

Acute administration of ketamine reverses the inhibition of mitochondrial respiratory chain induced by chronic mild stress

Rezin, G. T., Gonçalves, C. L., Daufenbach, J. F., Fraga, D. B., Santos, P. M. L., Ferreira, G. K., Hermani, F. V., Comim, C. M., Quevedo, J., & STRECK, E. L. (2009) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2009.03.010 · Cited by 71 · see citing works

Mitophagy in depression: Pathophysiology and treatment targets

Tripathi, A., Scaini, G., Barichello, T., Quevedo, J., & Pillai, A. (2021) · Mitochondrion · doi:10.1016/j.mito.2021.08.016 · Cited by 69 · see citing works

Brain responses to chronic social defeat stress: Effects on regional oxidative metabolism as a function of a hedonic trait, and gene expression in susceptible and resilient rats

Kanarik, M., O’Leary, A., Matrov, D., Kõiv, K., Sharp, T., Panksepp, J., & Harro, J. (2010) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2010.06.015 · Cited by 67 · see citing works

Linking Mitochondria to Synapses: New Insights for Stress-Related Neuropsychiatric Disorders

Jeanneteau, F. D., & Arango-Lievano, M. (2016) · Neural Plasticity · doi:10.1155/2016/3985063 · Cited by 63 · see citing works

Transcranial Photobiomodulation For The Management Of Depression: Current Perspectives

Askalsky, P., & Iosifescu, D. V. (2019) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s188906 · Cited by 63 · see citing works

The Mitochondrion as Potential Interface in Early-Life Stress Brain Programming

Hoffmann, A., & Spengler, D. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00306 · Cited by 63 · see citing works

Increased peripheral blood expression of electron transport chain genes in bipolar depression

Beech, R. D., Lowthert, L., Leffert, J. J., Mason, P. N., Taylor, M. M., Umlauf, S., Lin, A., Lee, J. Y., Maloney, K. H., Muralidharan, A., et al. (2010) · Bipolar Disorders · doi:10.1111/j.1399-5618.2010.00882.x · Cited by 62 · see citing works

Targeting Oxidative Stress, Cytokines and Serotonin Interactions Via Indoleamine 2, 3 Dioxygenase by Coenzyme Q10: Role in Suppressing Depressive Like Behavior in Rats

Abuelezz, S. A., Hendawy, N., & Magdy, Y. (2016) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-016-9712-7 · Cited by 61 · see citing works

Nicotinamide mononucleotide ameliorates the depression-like behaviors and is associated with attenuating the disruption of mitochondrial bioenergetics in depressed mice

Xie, X., Yu, C., Zhou, J., Xiao, Q., Shen, Q., Xiong, Z., Li, Z., & Fu, Z. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.11.147 · Cited by 61 · see citing works

Severe life stress, mitochondrial dysfunction, and depressive behavior: A pathophysiological and therapeutic perspective

Allen, J., Caruncho, H. J., & Kalynchuk, L. E. (2020) · Mitochondrion · doi:10.1016/j.mito.2020.11.010 · Cited by 60 · see citing works

Antidepressant Action on Mitochondrial Dysfunction in Psychiatric Disorders

Adzic, M., Brkic, Z., Bulajic, S., Mitic, M., & Radojcic, M. B. (2016) · Drug Development Research · doi:10.1002/ddr.21332 · Cited by 60 · see citing works

Sigma-1 receptor: A potential target for the development of antidepressants

Wang, Y., Xia, C., Jia, H., He, J., Lian, W., Yan, Y., Wang, W., Zhang, W., & Xu, J. (2022) · Neurochemistry International · doi:10.1016/j.neuint.2022.105390 · Cited by 57 · see citing works

Increased ratio of anti-apoptotic to pro-apoptotic Bcl2 gene-family members in lithium-responders one month after treatment initiation

Lowthert, L., Leffert, J. J., Lin, A., Umlauf, S., Maloney, K. H., Muralidharan, A., Lorberg, B. A., Mane, S., Zhao, H., Sinha, R., et al. (2012) · Biology of Mood & Anxiety Disorders · doi:10.1186/2045-5380-2-15 · Cited by 57 · see citing works

Leukocyte Mitochondrial DNA Copy Number in Blood Is Not Associated with Major Depressive Disorder in Young Adults

Hé, Y., Tang, J., Li, Z., Li, H., Liao, Y., Tang, Y., Tan, L., Chen, J., Xia, K., & Chen, X. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096869 · Cited by 56 · see citing works

Medial Forebrain Bundle Deep Brain Stimulation Reverses Anhedonic-Like Behavior in a Chronic Model of Depression: Importance of BDNF and Inflammatory Cytokines

Dandekar, M. P., Saxena, A., Scaini, G., Shin, J. H., Migut, A., Giridharan, V. V., Zhou, Y., Barichello, T., Soares, J. C., Quevedo, J., et al. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1381-5 · Cited by 56 · see citing works

Oral treatment with amitriptyline induces coenzyme Q deficiency and oxidative stress in psychiatric patients

Moreno-Fernández, A. M., Cordero, M. D., Garrido-Maraver, J., Alcocer-Gómez, E., Casas-Barquero, N., Carmona-López, M. I., Sánchez-Alcázar, J. A., & de Miguel, M. (2012) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.11.002 · Cited by 54 · see citing works

Activity of mitochondrial respiratory chain is increased by chronic administration of antidepressants

Scaini, G., Maggi, D. D., De-Nês, B. T., Gonçalves, C. L., Ferreira, G. K., Teodorak, B. P., Bez, G. D., Ferreira, G. C., Schuck, P. F., Quevedo, J., et al. (2011) · Acta Neuropsychiatrica · doi:10.1111/j.1601-5215.2011.00548.x · Cited by 53 · see citing works

Behavioral effects of nicotinic antagonist mecamylamine in a rat model of depression: prefrontal cortex level of BDNF protein and monoaminergic neurotransmitters

Aboul‐Fotouh, S. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3745-5 · Cited by 53 · see citing works

Evaluation of behavioral and neurochemical changes induced by ketamine in rats: Implications as an animal model of mania

Ghedim, F. V., Fraga, D. B., Deroza, P. F., Oliveira, M. B., Valvassori, S. S., Steckert, A. V., Budni, J., Dal‐Pizzol, F., Quevedo, J., & Zugno, A. I. (2012) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.08.010 · Cited by 53 · see citing works

Evaluation of Krebs cycle enzymes in the brain of rats after chronic administration of antidepressants

Scaini, G., Santos, P. M. L., Benedet, J., Rochi, N., Gomes, L. M., Borges, L. S., Rezin, G. T., Pezente, D. P., Quevedo, J., & STRECK, E. L. (2010) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2010.03.006 · Cited by 53 · see citing works

Molecular Mechanisms Underlying the Anti-depressant Effects of Resveratrol: a Review

de Oliveira, M. R., Chenet, A. L., Duarte, A. R., Scaini, G., & Quevedo, J. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0680-6 · Cited by 53 · see citing works

Pulsed Light Irradiation Improves Behavioral Outcome in a Rat Model of Chronic Mild Stress

Wu, X., Alberico, S. L., Moges, H., Taboada, L. H. D., Tedford, C. E., & Anders, J. J. (2012) · Lasers in Surgery and Medicine · doi:10.1002/lsm.22004 · Cited by 51 · see citing works

Protein biomarkers of susceptibility and resilience to stress in a rat model of depression

Palmfeldt, J., Henningsen, K., Eriksen, S. A., Müller, H. K., & Wiborg, O. (2016) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2016.04.001 · Cited by 49 · see citing works

Chronic variable stress impairs energy metabolism in prefrontal cortex and hippocampus of rats: prevention by chronic antioxidant treatment

Tagliari, B., Noschang, C. G., Ferreira, A. G. K., Ferrari, O. A., Feksa, L. R., Wannmacher, C. M. D., Dalmaz, C., & Wyse, Â. T. D. S. (2010) · Metabolic Brain Disease · doi:10.1007/s11011-010-9194-x · Cited by 48 · see citing works

Conditional deletion of Ndufs4 in dopaminergic neurons promotes Parkinson’s disease-like non-motor symptoms without loss of dopamine neurons

Choi, W., Kim, H.-W., Tronche, F., Palmiter, R. D., Storm, D. R., & Xia, Z. (2017) · Scientific Reports · doi:10.1038/srep44989 · Cited by 48 · see citing works

Genetic biomarkers for differential diagnosis of major depressive disorder and bipolar disorder: A systematic and critical review

Menezes, I. C., Baes, C. V. W., Lacchini, R., & Juruena, M. F. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.01.008 · Cited by 47 · see citing works

Proteomic characterization of hippocampus of chronically socially isolated rats treated with fluoxetine: Depression-like behaviour and fluoxetine mechanism of action

Perić, I., Costina, V., Stanisavljević, A., Findeisen, P., & Filipović, D. (2018) · Neuropharmacology · doi:10.1016/j.neuropharm.2018.03.034 · Cited by 47 · see citing works

Impaired mitochondrial complex I function as a candidate driver in the biological stress response and a concomitant stress-induced brain metabolic reprogramming in male mice

Emmerzaal, T. L., Preston, G. J., Geenen, B., Verweij, V. G. M., Wiesmann, M., Vasileiou, E., Grüter, F., de Groot, C., Schoorl, J., de Veer, R., et al. (2020) · Translational Psychiatry · doi:10.1038/s41398-020-0858-y · Cited by 47 · see citing works

Link between depression and cardiovascular diseases due to epigenomics and proteomics: Focus on energy metabolism

Kahl, K. G., Stapel, B., & Frieling, H. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.09.004 · Cited by 47 · see citing works

Methylene blue and its analogues as antidepressant compounds

Delport, A., Harvey, B. H., Petzer, A., & Petzer, J. P. (2017) · Metabolic Brain Disease · doi:10.1007/s11011-017-0081-6 · Cited by 46 · see citing works

Molecular correlates of mitochondrial dysfunctions in major depression: Evidence from clinical and rodent studies

Rappeneau, V., Wilmes, L., & Touma, C. (2020) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2020.103555 · Cited by 46 · see citing works

Neuroinflammation and Mitochondrial Dysfunction Link Social Stress to Depression

Hollis, F., Pope, B. S., Gorman‐Sandler, E., & Wood, S. K. (2022) · Current topics in behavioral neurosciences · doi:10.1007/7854_2021_300 · Cited by 47 · see citing works

Psychosocial experiences are associated with human brain mitochondrial biology

Trumpff, C., Monzel, A. S., Sandi, C., Menon, V., Klein, H., Fujita, M., Lee, A., Petyuk, V., Hurst, C. D., Duong, D. M., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2317673121 · Cited by 45 · see citing works

Dynamic proteomic analysis of protein expression profiles in whole brain of Balb/c mice subjected to unpredictable chronic mild stress: Implications for depressive disorders and future therapies

Liu, Y., Yang, N., Hao, W., Zhao, Q., Ying, T., Liu, S., Li, Q., Liang, Y., Wang, T., Dong, Y., et al. (2011) · Neurochemistry International · doi:10.1016/j.neuint.2011.02.019 · Cited by 45 · see citing works

Impaired Brain Energy Metabolism: Involvement in Depression and Hypothyroidism

Głombik, K., Detka, J., Kurek, A., & Budziszewska, B. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.586939 · Cited by 45 · see citing works

Synaptoproteomics of learned helpless rats involve energy metabolism and cellular remodeling pathways in depressive-like behavior and antidepressant response

Mallei, A., Giambelli, R., Gass, P., Racagni, G., Mathé, A. A., Vollmayr, B., & Popoli, M. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.12.012 · Cited by 44 · see citing works

Transcriptional profiling of mitochondria associated genes in prefrontal cortex of subjects with major depressive disorder

Wang, Q., & Dwivedi, Y. (2016) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2016.1197423 · Cited by 44 · see citing works

Mini-review: Brain energy metabolism and its role in animal models of depression, bipolar disorder, schizophrenia and autism

Kolář, D., Kletečková, L., Brožka, H., & Valeš, K. (2021) · Neuroscience Letters · doi:10.1016/j.neulet.2021.136003 · Cited by 43 · see citing works

Mapping patterns of depression-related brain regions with cytochrome oxidase histochemistry: Relevance of animal affective systems to human disorders, with a focus on resilience to adverse events

Harro, J., Kanarik, M., Matrov, D., & Panksepp, J. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.02.016 · Cited by 44 · see citing works

Sex-dependent mental illnesses and mitochondria

Shimamoto, A., & Rappeneau, V. (2017) · Schizophrenia Research · doi:10.1016/j.schres.2017.02.025 · Cited by 41 · see citing works

Exploring the mechanisms of action of the antidepressant effect of the ketogenic diet

Ricci, A. L., Idzikowski, M. A., Soares, C. N., & Brietzke, E. M. (2020) · Reviews in the Neurosciences · doi:10.1515/revneuro-2019-0073 · Cited by 42 · see citing works

Advances in understanding mechanisms and therapeutic targets to treat comorbid depression and cardiovascular disease

Pope, B. S., & Wood, S. K. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.06.031 · Cited by 41 · see citing works

Administration of Harmine and Imipramine Alters Creatine Kinase and Mitochondrial Respiratory Chain Activities in the Rat Brain

Réus, G. Z., Stringari, R. B., Gonçalves, C. L., Scaini, G., Carvalho‐Silva, M., Jeremias, G. C., Jeremias, I. C., Ferreira, G. K., STRECK, E. L., Hallak, J. E. C., et al. (2011) · Depression Research and Treatment · doi:10.1155/2012/987397 · Cited by 41 · see citing works

Treatment with tianeptine induces antidepressive-like effects and alters the neurotrophin levels, mitochondrial respiratory chain and cycle Krebs enzymes in the brain of maternally deprived adult rats

Della, F. P., Abelaira, H. M., Réus, G. Z., dos Santos, M. A. B., Tomaz, D. B., Antunes, A. R., Scaini, G., Morais, M. O. D. S., STRECK, E. L., & Quevedo, J. (2013) · Metabolic Brain Disease · doi:10.1007/s11011-012-9375-x · Cited by 40 · see citing works

The possible beneficial effects of creatine for the management of depression

Pazini, F. L., Cunha, M. P., & Rodrigues, A. L. S. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.08.029 · Cited by 44 · see citing works

Mitochondria could be a potential key mediator linking the intestinal microbiota to depression

Chen, J., & Vitetta, L. (2020) · Journal of Cellular Biochemistry · doi:10.1002/jcb.29311 · Cited by 36 · see citing works

PCSK9 Inhibition Reduces Depressive like Behavior in CUMS-Exposed Rats: Highlights on HMGB1/RAGE/TLR4 Pathway, NLRP3 Inflammasome Complex and IDO-1

Hendawy, N., Salaheldin, T. H., & Abuelezz, S. A. (2023) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-023-10060-3 · Cited by 38 · see citing works

Mitochondrial DNA copy number, damage, repair and degradation in depressive disorder

Czarny, P. L., Wigner, P., Strycharz, J., Świderska, E., Synowiec, E., Szatkowska, M., Śliwińska, A., Talarowska, M. E., Szemraj, J., Su, K., et al. (2019) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2019.1588993 · Cited by 38 · see citing works

Chronic treatment with coenzyme Q10 reverses restraint stress-induced anhedonia and enhances brain mitochondrial respiratory chain and creatine kinase activities in rats

Aboul‐Fotouh, S. (2013) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e3283654029 · Cited by 38 · see citing works

UNIVERSIDADE DO EXTREMO SUL CATARINENSE - UNESC

Saúde, U. A. D., & Rosa, J. L. N. D. (2011) · Cited by 36 · see citing works

Effect of neuropsychiatric medications on mitochondrial function: For better or for worse

Emmerzaal, T. L., Nijkamp, G., Veldić, M., Rahman, S., Andreazza, A. C., Morava, É., Rodenburg, R. J., & Kozicz, T. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.05.001 · Cited by 33 · see citing works

Effect of acute administration of ketamine and imipramine on creatine kinase activity in the brain of rats

Assis, L. C., Rezin, G. T., Comim, C. M., Valvassori, S. S., Jeremias, I. C., Zugno, A. I., Quevedo, J., & STRECK, E. L. (2009) · Brazilian Journal of Psychiatry · doi:10.1590/s1516-44462009000300010 · Cited by 34 · see citing works

The depression GWAS risk allele predicts smaller cerebellar gray matter volume and reduced SIRT1 mRNA expression in Chinese population

Liu, W., Yan, H., Zhou, D., Cai, X. M., Zhang, Y., Li, S., Li, H., Li, S., Zhou, D., Li, X., et al. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0675-3 · Cited by 34 · see citing works

The effect of chronic tianeptine administration on the brain mitochondria: direct links with an animal model of depression

Głombik, K., Stachowicz, A., Olszanecki, R., Ślusarczyk, J., Trojan, E., Lasoń, W., Kubera, M., Budziszewska, B., Spedding, M., & Basta‐Kaim, A. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-9807-4 · Cited by 32 · see citing works

Glutathione Depletion, Lipid Peroxidation and Mitochondrial Dysfunction Are Induced by Chronic Stress in Rat Brain

Madrigal, J. L. M. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00208-6 · Cited by 381 · see citing works

Chronic mild stress damages mitochondrial ultrastructure and function in mouse brain

Gong, Y. L., Chai, Y., Ding, J., Sun, X., & Hu, G. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.11.006 · Cited by 183 · see citing works

Mitochondrial Respiratory Chain Function in Major Depression

Fernström, J., Mellon, S. H., Picard, M. A., McGill, M. A., Reus, V. I., Hough, C. M., Epel, E. S., Wolkowitz, O. M., & Lindqvist, D. (2020) · Biological Psychiatry · doi:10.1016/j.biopsych.2020.02.515 · Cited by 1 · see citing works

Chronic stress induces depression-like behavior in rats through affecting brain mitochondrial function and inflammation

Wang, L., Xu, Y., Jiang, M., Wang, M., Ji, M., Xie, X., & Sheng, H. (2024) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2024.107261 · Cited by 21 · see citing works

Stable Isotope-Resolved Metabolomics Reveals the Abnormal Brain Glucose Catabolism in Depression Based on Chronic Unpredictable Mild Stress Rats

Linghu, T., Liu, S., Gao, Y., Han, Y., Tian, J., & Qin, X. (2021) · Journal of Proteome Research · doi:10.1021/acs.jproteome.1c00155 · Cited by 28 · see citing works