Animal model of depression: Pharmacological sensitivity of a hedonic deficit
Open accessAbstract
A reduction in sucrose and saccharine consumption following chronic stress is reported for the rat. This deficit may be related to consummatory deficits seen in endogenous depression. To further examine this state pharmacologically, stressed rats were treated with the antidepressant imipramine. Despite a general absence of appetitive effects (or in some cases mild anorexia) imipramine significantly restored saccharine consumption in a variety of tests. The pharmacological similarity of the deficit to the changes accompanying affective disorders further supports the potential applicability of the chronic stress model.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Computational Handbook of Statistics.
Crofts, A., Bruning, J. L., & Kintz, B. L. (1969) · Journal of the American Statistical Association · doi:10.2307/2283756 · Cited by 2,339 · see citing works
Klein, D. F. (1974) · Archives of General Psychiatry · doi:10.1001/archpsyc.1974.01760160005001 · Cited by 601 · see citing works
GUSTATORY NERVE IMPULSES IN RAT, CAT AND RABBIT
Pfaffmann, C. (1955) · Journal of Neurophysiology · doi:10.1152/jn.1955.18.5.429 · Cited by 279 · see citing works
Amitriptyline and scopolamine in an animal model of depression
Katz, R. J., & Hersh, S. I. (1981) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(81)90008-7 · Cited by 101 · see citing works
Self-citationRoth, K. A., & Katz, R. J. (1981) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(81)90006-3 · Cited by 73 · see citing works
Self-citationLiljestrand, G., & Zotterman, Y. (1954) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1954.tb01177.x · Cited by 56 · see citing works
Manic depressive syndrome: a physiologic disease.
Sh, K. (1966) · PubMed · Cited by 9 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Katz, R. J., K. A. Roth, I. A. Mefford, B. J. Carroll and J. Barchas. The chronically stressed rat--a novel animal of endog- enomorphic depression. Proc. 3rd Int. Cong. Biol. Psychiat. Stockholm, Sweden, 1981.
Cited by
Sorted by citations
Willner, P., Towell, A., Sampson, D., Sophokleous, S., & Muscat, R. (1987) · Psychopharmacology · doi:10.1007/bf00187257 · Cited by 1,993 · see citing works
Willner, P. (1997) · Psychopharmacology · doi:10.1007/s002130050456 · Cited by 1,832 · see citing works
Willner, P. (2005) · Neuropsychobiology · doi:10.1159/000087097 · Cited by 1,605 · see citing works
The validity of animal models of depression
Willner, P. (1984) · Psychopharmacology · doi:10.1007/bf00427414 · Cited by 1,415 · see citing works
Chronic mild stress-induced anhedonia: A realistic animal model of depression
Willner, P., Muscat, R., & Papp, M. (1992) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80194-0 · Cited by 1,160 · see citing works
Depression, Stress, and Anhedonia: Toward a Synthesis and Integrated Model
Pizzagalli, D. A. (2014) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050212-185606 · Cited by 1,155 · see citing works
Maier, S. F., & Watkins, L. R. (1998) · Psychological Review · doi:10.1037/0033-295x.105.1.83 · Cited by 1,130 · see citing works
The chronic mild stress (CMS) model of depression: History, evaluation and usage
Willner, P. (2017) · Neurobiology of Stress · doi:10.1016/j.ynstr.2016.08.002 · Cited by 959 · see citing works
Chronic Stress Causes Frontostriatal Reorganization and Affects Decision-Making
Dias-Ferreira, E., Sousa, J. C., Melo, I., Morgado, P., Mesquita, A. R., Cerqueira, J. J., Costa, R. M., & Sousa, N. (2009) · Science · doi:10.1126/science.1171203 · Cited by 858 · see citing works
Dopamine system dysregulation in major depressive disorders
Belujon, P., & Grace, A. A. (2017) · International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyx056 · Cited by 754 · see citing works
Prefrontal cortex and depression
Pizzagalli, D. A., & Roberts, A. C. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-021-01101-7 · Cited by 644 · see citing works
Alterations induced by gestational stress in brain morphology and behaviour of the offspring
Weinstock, M. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(01)00018-1 · Cited by 791 · see citing works
Stress-Induced Anhedonia in Mice is Associated with Deficits in Forced Swimming and Exploration
Strekalova, T. V., Spanagel, R., Bartsch, D., Henn, F. A., & Gass, P. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300532 · Cited by 564 · see citing works
Papp, M., Willner, P., & Muscat, R. (1991) · Psychopharmacology · doi:10.1007/bf02244188 · Cited by 542 · see citing works
Endotoxin produces a depressive-like episode in rats
Yirmiya, R. (1996) · Brain Research · doi:10.1016/0006-8993(95)01415-2 · Cited by 604 · see citing works
Neural Mechanisms of Stress Resilience and Vulnerability
Franklin, T. B., Saab, B. J., & Mansuy, I. M. (2012) · Neuron · doi:10.1016/j.neuron.2012.08.016 · Cited by 500 · see citing works
Leptin: A potential novel antidepressant
Lu, X.-Y., Kim, C. S., Frazer, A., & Zhang, W. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0508901103 · Cited by 446 · see citing works
Dendritic Spines in Depression: What We Learned from Animal Models
Qiao, H., Li, M.-X., Xu, C. S., Chen, H.-B., An, S.-C., & Ma, X. (2016) · Neural Plasticity · doi:10.1155/2016/8056370 · Cited by 442 · see citing works
Animal models of depression: An overview
Willner, P. (1990) · Pharmacology & Therapeutics · doi:10.1016/0163-7258(90)90076-e · Cited by 428 · see citing works
Neurobiology of chronic mild stress: parallels to major depression
Hill, M. N., Hellemans, K. G. C., Verma, P., Gorzalka, B. B., & Weinberg, J. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.07.001 · Cited by 420 · see citing works
Social model of depression in mice of C57BL/6J strain
Kudryavtseva, N. N., Bakshtanovskaya, I. V., & Koryakina, L. A. (1991) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(91)90284-9 · Cited by 404 · see citing works
Animal models of major depression and their clinical implications
Czéh, B., Fuchs, E., Wiborg, O., & Simon, M. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2015.04.004 · Cited by 375 · see citing works
Animal models of psychiatric disorders
Koob, G. F., & Zimmer, A. (2012) · Handbook of clinical neurology · doi:10.1016/b978-0-444-52002-9.00009-7 · Cited by 337 · see citing works
Stress, depression and the mesolimbic dopamine system
Cabib, S., & Puglisi‐Allegra, S. (1996) · Psychopharmacology · doi:10.1007/s002130050142 · Cited by 314 · see citing works
The leptin hypothesis of depression: a potential link between mood disorders and obesity?
Lu, X.-Y. (2007) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2007.10.010 · Cited by 303 · see citing works
Behavioral animal models of depression
Yan, H., Cao, X., Das, M. K., Zhu, X., & Gao, T. (2010) · Neuroscience Bulletin · doi:10.1007/s12264-010-0323-7 · Cited by 298 · see citing works
Animal Models of Depression: Utility for Transgenic Research
Porsolt, R. D. (2000) · Reviews in the Neurosciences · doi:10.1515/revneuro.2000.11.1.53 · Cited by 284 · see citing works
Chronic Mild Stress and Sucrose Consumption: Validity as a Model of Depression
Forbes, N., Stewart, C. A., Matthews, K., & REID, I. (1996) · Physiology & Behavior · doi:10.1016/s0031-9384(96)00305-8 · Cited by 281 · see citing works
Moreau, J., Jenck, F., Martin, J. R., Mortas, P., & Haefely, W. E. (1992) · European Neuropsychopharmacology · doi:10.1016/0924-977x(92)90035-7 · Cited by 250 · see citing works
Selecting an Appropriate Animal Model of Depression
Hao, Y., Ge, H., Sun, M., & Gao, Y. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20194827 · Cited by 247 · see citing works
Suppression of sucrose drinking by chronic mild unpredictable stress: A methodological analysis
Muscat, R., & Willner, P. (1992) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80192-7 · Cited by 231 · see citing works
Models of Depression: Unpredictable Chronic Mild Stress in Mice
Nollet, M., Guisquet, A. L., & Belzung, C. (2013) · Current Protocols in Pharmacology · doi:10.1002/0471141755.ph0565s61 · Cited by 230 · see citing works
Dang, H., Chen, Y., Liu, X., Wang, Q., Wang, L., Jia, W. W.-G., & Wang, Y. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.07.020 · Cited by 224 · see citing works
Sucrose consumption as an hedonic measure following chronic unpredictable mild stress
Matthews, K., Forbes, N., & Reid, I. (1995) · Physiology & Behavior · doi:10.1016/0031-9384(94)00286-e · Cited by 219 · see citing works
Chronic mild stress-induced anhedonia: Greater effect in a genetic rat model of depression
Puciłowski, O., Overstreet, D. H., Rezvani, A. H., & Janowsky, D. S. (1993) · Physiology & Behavior · doi:10.1016/0031-9384(93)90351-f · Cited by 216 · see citing works
Measuring behavior in mice with chronic stress depression paradigm
Strekalova, T., & Steinbusch, H. W. M. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2009.12.014 · Cited by 207 · see citing works
Behavioral effects of neuropeptides in rodent models of depression and anxiety
Rotzinger, S., Lovejoy, D. A., & Tan, L. A. (2010) · Peptides · doi:10.1016/j.peptides.2009.12.015 · Cited by 211 · see citing works
Making Sense of Rodent Models of Anhedonia
Scheggi, S., Montis, M. G. D., & Gambarana, C. (2018) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyy083 · Cited by 209 · see citing works
Animal models of depression in drug discovery: A historical perspective
McArthur, R. A., & Borsini, F. (2006) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.06.005 · Cited by 209 · see citing works
Konkle, A. T. M., Baker, S. L., Kentner, A. C., Barbagallo, L. S.-M., Merali, Z., & Bielajew, C. H. (2003) · Brain Research · doi:10.1016/j.brainres.2003.08.047 · Cited by 199 · see citing works
von Frijtag, J. C., Reijmers, L. G. J. E., van der Harst, J. E., Leus, I. E., van den Bos, R., & Spruijt, B. M. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(00)00300-4 · Cited by 201 · see citing works
Reliability of the chronic mild stress model of depression: A user survey
Willner, P. (2017) · Neurobiology of Stress · doi:10.1016/j.ynstr.2016.08.001 · Cited by 198 · see citing works
Hu, C., Luo, Y., Wang, H., Kuang, S., Liang, G., Yang, Y., Mai, S., & Yang, J. (2017) · PLoS ONE · doi:10.1371/journal.pone.0185129 · Cited by 197 · see citing works
Rezin, G. T., Cardoso, M. R., Gonçalves, C. L., Scaini, G., Fraga, D. B., Riegel, R. E., Comim, C. M., Quevedo, J., & Streck, E. L. (2008) · Neurochemistry International · doi:10.1016/j.neuint.2008.09.012 · Cited by 197 · see citing works
Zhao, Z., Wang, W., Guo, H., & Zhou, D. (2008) · Behavioural Brain Research · doi:10.1016/j.bbr.2008.06.030 · Cited by 187 · see citing works
In vivo antioxidant status: A putative target of antidepressant action
Zafir, A., Ara, A., & Banu, N. (2009) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2008.11.010 · Cited by 183 · see citing works
Adult Neurogenesis and Mental Illness
Schoenfeld, T. J., & Cameron, H. A. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.230 · Cited by 183 · see citing works
Chronic mild stress damages mitochondrial ultrastructure and function in mouse brain
Gong, Y. L., Chai, Y., Ding, J., Sun, X., & Hu, G. (2010) · Neuroscience Letters · doi:10.1016/j.neulet.2010.11.006 · Cited by 183 · see citing works
Regulation of dopamine system responsivity and its adaptive and pathological response to stress
Belujon, P., & Grace, A. A. (2015) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2014.2516 · Cited by 185 · see citing works
Neurobehavioral deficits in db/db diabetic mice
Sharma, A. N., Elased, K. M., Garrett, T. L., & Lucot, J. B. (2010) · Physiology & Behavior · doi:10.1016/j.physbeh.2010.07.002 · Cited by 180 · see citing works
Kundaković, M., Lim, S. C., Gudsnuk, K. M., & Champagne, F. A. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2013.00078 · Cited by 172 · see citing works
Update in the methodology of the chronic stress paradigm: internal control matters
Strekalova, T., Couch, Y., Kholod, N., Boyks, M., Malin, D., Leprince, P., & Steinbusch, H. M. (2011) · Behavioral and Brain Functions · doi:10.1186/1744-9081-7-9 · Cited by 163 · see citing works
How to study anxiety and depression in rodent models of chronic pain?
Kremer, M., Becker, L. J., Barrot, M., & Yalçın, İ. (2020) · European Journal of Neuroscience · doi:10.1111/ejn.14686 · Cited by 167 · see citing works
van Dijken, H. H., Mos, J., der Heyden, J. A. M. V., & Tilders, F. J. H. (1992) · Physiology & Behavior · doi:10.1016/0031-9384(92)90375-c · Cited by 162 · see citing works
Chronic mild stress affects sucrose intake and sleep in rats
Grønli, J., Murison, R. C. C., Bjorvatn, B., Sørensen, E., Portas, C. M., & Ursin, R. (2003) · Behavioural Brain Research · doi:10.1016/s0166-4328(03)00252-3 · Cited by 158 · see citing works
Animal models of depression: Parallels and correlates to severe depression in humans
Jesberger, J. A., & Richardson, J. S. (1985) · Biological Psychiatry · doi:10.1016/0006-3223(85)90156-8 · Cited by 156 · see citing works
De La Garza, R. (2005) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.03.016 · Cited by 153 · see citing works
Guo, J.-Y., Li, C.-Y., Ruan, Y.-P., Sun, M., Qi, X.-L., Zhao, B.-S., & Luo, F. (2009) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2009.03.076 · Cited by 148 · see citing works
Rodent tests of depression and anxiety: Construct validity and translational relevance
Gencturk, S., & Unal, G. (2024) · Cognitive, Affective, & Behavioral Neuroscience · doi:10.3758/s13415-024-01171-2 · Cited by 138 · see citing works
Chronic mild stress paradigm as a rat model of depression: facts, artifacts, and future perspectives
Strekalova, T. V., Liu, Y., Kiselev, D., Khairuddin, S., Chiu, J. L. Y., Lam, J., Chan, Y., Pavlov, D., Proshin, A. T., Lesch, K., et al. (2022) · Psychopharmacology · doi:10.1007/s00213-021-05982-w · Cited by 146 · see citing works
Failure to Change Exploration or Saccharin Preference In Rats Exposed to Chronic Mild Stress
Harris, R. B. S. (1997) · Physiology & Behavior · doi:10.1016/s0031-9384(97)00425-3 · Cited by 144 · see citing works
Effects of chronic social stress during lactation on maternal behavior and growth in rats
Nephew, B. C., & Bridges, R. S. (2011) · Stress · doi:10.3109/10253890.2011.605487 · Cited by 138 · see citing works
Sequeira‐Cordero, A., Salas-Bastos, A., Fornaguera, J., & Brenes, J. C. (2019) · Scientific Reports · doi:10.1038/s41598-019-53624-1 · Cited by 140 · see citing works
Chronic mild stress for modeling anhedonia
Wiborg, O. (2013) · Cell and Tissue Research · doi:10.1007/s00441-013-1664-0 · Cited by 138 · see citing works
Ethopharmacology of imipramine in the forced-swimming test: gender differences
Barros, H. M. T., & Ferigolo, M. (1998) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(98)00029-3 · Cited by 136 · see citing works
Animal models of CNS disorders
McGonigle, P. (2013) · Biochemical Pharmacology · doi:10.1016/j.bcp.2013.06.016 · Cited by 135 · see citing works
Stressor-induced anhedonia in the mesocorticolimbic system
Zacharko, R. M., & Anisman, H. (1991) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(05)80032-6 · Cited by 135 · see citing works
Strekalova, T. V., Gorenkova, N., Shunk, E., Dolgov, O., & Bartsch, D. (2006) · Behavioural Pharmacology · doi:10.1097/00008877-200605000-00008 · Cited by 130 · see citing works
Huynh, T. N., Krigbaum, A. M., Hanna, J. J., & Conrad, C. D. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.03.038 · Cited by 129 · see citing works
Lei, Y., Wang, J., Wang, D., Li, C., Liu, B., Fang, X., You, J., Guo, M., & Lu, X.-Y. (2020) · Molecular Psychiatry · doi:10.1038/s41380-019-0352-1 · Cited by 131 · see citing works
Buisman‐Pijlman, F. T. A., Wolterink, G., & van Ree, J. M. (2003) · Behavioural Brain Research · doi:10.1016/s0166-4328(02)00124-9 · Cited by 128 · see citing works
Markov, D. D. (2022) · Brain Sciences · doi:10.3390/brainsci12101287 · Cited by 125 · see citing works
Harro, J., Tõnissaar, M., Eller, M., Kask, A., & Oreland, L. (2001) · Brain Research · doi:10.1016/s0006-8993(01)02256-9 · Cited by 124 · see citing works
Dopaminergic mechanism of imipramine action in an animal model of depression
Muscat, R., Sampson, D., & Willner, P. (1990) · Biological Psychiatry · doi:10.1016/0006-3223(90)90577-o · Cited by 122 · see citing works
Ma, X., Jiang, D., Jiang, W., Wang, F., Jia, M., Wu, J., Hashimoto, K., Dang, Y., & Gao, C. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020955 · Cited by 116 · see citing works
Tejani‐Butt, S. M., Paré, W. P., & Yang, J. (1994) · Brain Research · doi:10.1016/0006-8993(94)91045-6 · Cited by 116 · see citing works
Nielsen, C. K., Arnt, J., & Sánchez, C. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(99)00110-2 · Cited by 115 · see citing works
Reversal of antidepressant action by dopamine antagonists in an animal model of depression
Sampson, D., Willner, P., & Muscat, R. (1991) · Psychopharmacology · doi:10.1007/bf02245655 · Cited by 115 · see citing works
Role of Mesolimbic Brain-Derived Neurotrophic Factor in Depression
Koo, J. W., Chaudhury, D., Han, M.-H., & Nestler, E. J. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2019.05.020 · Cited by 112 · see citing works
Animal models of pain: Diversity and benefits
Abboud, C., Duveau, A., Bouali‐Benazzouz, R., Massé, K. L., Mattar, J., Brochoire, L., Fossat, P., Boué‐Grabot, É., Hleihel, W., & Landry, M. (2020) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2020.108997 · Cited by 112 · see citing works
SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action
Oh, Y., Gao, P., Lee, K.-W., Ceglia, I., Seo, J., Zhang, X., Ahn, J., Chait, B. T., Patel, D. J., Kim, Y. D., et al. (2013) · Cell · doi:10.1016/j.cell.2013.01.014 · Cited by 112 · see citing works
Lin, Y., Liu, A., Xu, Y., Tie, L., Yu, H., & Li, X.-J. (2005) · Behavioural Brain Research · doi:10.1016/j.bbr.2005.06.034 · Cited by 108 · see citing works
Animal models of depression: pros and cons
Harro, J. (2018) · Cell and Tissue Research · doi:10.1007/s00441-018-2973-0 · Cited by 104 · see citing works
Citalopram counteracts depressive-like symptoms evoked by chronic social stress in rats
Rygula, R., Abumaria, N., Flügge, G., Hiemke, C., Fuchs, E., Rüther, E., & Havemann-Reinecke, U. (2006) · Behavioural Pharmacology · doi:10.1097/01.fbp.0000186631.53851.71 · Cited by 104 · see citing works
GABAB Receptors and Depression: Current Status
Cryan, J. F., & Slattery, D. A. (2010) · Advances in pharmacology · doi:10.1016/s1054-3589(10)58016-5 · Cited by 103 · see citing works
HPA Axis Interactions with Behavioral Systems
Packard, A. E. B., Egan, A. E., & Ulrich‐Lai, Y. M. (2016) · Comprehensive physiology · doi:10.1002/cphy.c150042 · Cited by 130 · see citing works
Binge alcohol drinking elicits persistent negative affect in mice
Lee, K. M., Coehlo, M. A., McGregor, H. A., Waltermire, R. S., & Szumlinski, K. K. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2015.05.055 · Cited by 96 · see citing works
Ethanol‐induced conditioned taste aversion in male Sprague‐Dawley rats: impact of age and stress
Anderson, R. I., Varlinskaya, E. I., & Spear, L. P. (2010) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2010.01307.x · Cited by 96 · see citing works
Mällo, T., O’Leary, A., Kõiv, K., Tõnissaar, M., Eller, M., & Harro, J. (2006) · Behavioural Brain Research · doi:10.1016/j.bbr.2006.11.022 · Cited by 98 · see citing works
Harkin, A., Houlihan, D. D., & Kelly, J. P. (2002) · Journal of Psychopharmacology · doi:10.1177/026988110201600201 · Cited by 98 · see citing works
Animal Behavioural Studies in the Evaluation of Antidepressant Drugs
Thiébot, M.-H., Martin, P., & Puech, A. J. (1992) · The British Journal of Psychiatry · doi:10.1192/s0007125000296670 · Cited by 96 · see citing works
Harro, J., Häidkind, R., Harro, M., Modiri, A., Gillberg, P., Pähkla, R., Matto, V., & Oreland, L. (1999) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(99)00043-7 · Cited by 95 · see citing works
Zurita, A., Martijena, I. D., Cuadra, G. R., Brandão, M. L., & Molina, V. A. (2000) · Behavioural Brain Research · doi:10.1016/s0166-4328(00)00302-8 · Cited by 94 · see citing works
Grundwald, N. J., & Brunton, P. J. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.08.010 · Cited by 94 · see citing works
Escorihuela, R. M., Tobeña, A., & Fernández‐Teruel, A. (1994) · Behavioural Brain Research · doi:10.1016/0166-4328(94)90157-0 · Cited by 94 · see citing works
Phillips, G. D., Howes, S. R., Whitelaw, R. B., Robbins, T. W., & Everitt, B. J. (1994) · Psychopharmacology · doi:10.1007/bf02245085 · Cited by 90 · see citing works
Behavioral and physiological effects of chronic mild stress in female rats
Baker, S. L., Kentner, A. C., Konkle, A. T. M., Barbagallo, L. S.-M., & Bielajew, C. H. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.10.019 · Cited by 91 · see citing works
Dang, H., Sun, L., Liu, X., Peng, B., Wang, Q., Jia, W. W.-G., Chen, Y., Pan, A., & Xiao, P. (2009) · Experimental Biology and Medicine · doi:10.3181/0812-rm-354 · Cited by 92 · see citing works
Lu, Y., Ho, C. S. H., McIntyre, R. S., Wang, W., & Ho, R. (2018) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2018.06.007 · Cited by 90 · see citing works
Markov, D. D., & Novosadova, E. V. (2022) · Biology · doi:10.3390/biology11111621 · Cited by 95 · see citing works
- Authors
- Katz, R. J.
- Affiliations
- University of Michigan (US)
- Corresponding author
- Katz, Richard J.
- ORCID
- Katz, Richard J.
- Venue
- Pharmacology Biochemistry and Behavior
- Publisher
- Elsevier BV
- Published
- 1982-06
- Volume
- 16
- Issue
- 6
- Pages
- 965-968
- ISSN
- 0091-3057 (ISSN-L)
- OpenAlex
- W2099660163
- Cited by
- 480
- References
- 7
- Citations by year
- 2026: 8 · 2025: 18 · 2024: 21 · 2023: 22 · 2022: 16 · 2021: 20 · 2020: 22 · 2019: 20 · 2018: 20 · 2017: 17 · 2016: 16 · 2015: 11 · 2014: 26 · 2013: 15 · 2012: 18
- FWCI
- 0.56
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Pharmacology Biochemistry and Behavior (publishedVersion)
- PubMed (publishedVersion)
- Deep Blue (University of Michigan) (submittedVersion)
- Funders
- National Institute of Mental Health
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- animal models of depression, chronic stress, sucrose intake, imipramine, antidepressant sensitivity, anorexia, mood disorders
- MeSH terms
- Animals, Depressive Disorder, Disease Models, Animal, Drinking, Eating, Humans, Imipramine, Male, Motivation, Rats, Inbred Strains, Stress, Physiological, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review