The beneficial effects of fruit polyphenols on brain aging

Free Radicals in the Physiological Control of Cell Function

Dröge, W. (2002) · Physiological Reviews · doi:10.1152/physrev.00018.2001 · Cited by 9,855 · see citing works

Aging: a theory based on free radical and radiation chemistry

Harman, D. (1956) · Journal of Gerontology · doi:10.1093/geronj/11.3.298 · Cited by 8,567 · see citing works

The Free Radical Theory of Aging Matures

BECKMAN, K. B., & AMES, B. N. (1998) · Physiological Reviews · doi:10.1152/physrev.1998.78.2.547 · Cited by 3,879 · see citing works

Neurodegenerative diseases and oxidative stress

Barnham, K. J., Masters, C. L., & Bush, A. I. (2004) · Nature Reviews Drug Discovery · doi:10.1038/nrd1330 · Cited by 3,683 · see citing works

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

Kuhn, H., Dickinson-Anson, H., & Gage, F. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-06-02027.1996 · Cited by 3,139 · see citing works

Oxidative Stress, Caloric Restriction, and Aging

Sohal, R. S., & Weindruch, R. H. (1996) · Science · doi:10.1126/science.273.5271.59 · Cited by 3,133 · see citing works

Biology of disease: free radicals and tissue injury.

Freeman, B. Α., & Jd, C. (1982) · PubMed · Cited by 3,059 · see citing works

Free radicals, antioxidants, and human disease: where are we now?

Halliwell, B. B., Gutteridge, J. M. C., & Cross, C. E. (1992) · PubMed · Cited by 2,155 · see citing works

Lipophilic and Hydrophilic Antioxidant Capacities of Common Foods in the United States

Wu, X., Beecher, G. R., Holden, J. M., Haytowitz, D. B., Gebhardt, S. E., & Prior, R. L. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf049696w · Cited by 1,738 · see citing works

Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported

Evans, D. A. (1989) · JAMA · doi:10.1001/jama.262.18.2551 · Cited by 1,627 · see citing works

Role of Free Radicals in the Neurodegenerative Diseases: Therapeutic Implications for Antioxidant Treatment

Halliwell, B. (2001) · Drugs & Aging · doi:10.2165/00002512-200118090-00004 · Cited by 1,502 · see citing works

Oxidative Stress in Neurodegenerative Diseases

Simonian, N. A., & Coyle, J. T. (1996) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pa.36.040196.000503 · Cited by 1,377 · see citing works

Oxidative stress and gene regulation

Allen, R. G., & Tresini, M. (2000) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(99)00242-7 · Cited by 1,297 · see citing works

Antioxidant Therapy: A New Pharmacological Approach in Shock, Inflammation, and Ischemia/Reperfusion Injury

Cuzzocrea, S., Riley, D. P., Caputi, A. P., & Salvemini, D. (2001) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01484-4 · Cited by 1,087 · see citing works

Neurodegenerative diseases and oxidative stress

Emerit, J., Edeas, M. A., & Bricaire, F. (2003) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2003.11.004 · Cited by 1,031 · see citing works

Reversals of age-related declines in neuronal signal transduction, cognitive, and motor behavioral deficits with blueberry, spinach, or strawberry dietary supplementation

Joseph, J. A., Shukitt-Hale, B., Denisova, N. A., Bielinski, D., Martin, A., McEwen, J. J., & Bickford, P. C. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-18-08114.1999 · Cited by 980 · see citing works

The Free Radical Theory of Aging

Harman, D. (2003) · Antioxidants and Redox Signaling · doi:10.1089/152308603770310202 · Cited by 926 · see citing works

Free radical theory of aging

Harman, D. (1992) · Mutation Research/DNAging · doi:10.1016/0921-8734(92)90030-s · Cited by 902 · see citing works

Oxidative stress in brain agingImplications for therapeutics of neurodegenerative diseases

Floyd, R. A., & Hensley, K. (2002) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00019-2 · Cited by 830 · see citing works

Antioxidants, Oxidative Stress, and Degenerative Neurological Disorders

Floyd, R. A. (1999) · Proceedings of The Society for Experimental Biology and Medicine · doi:10.1046/j.1525-1373.1999.d01-140.x · Cited by 824 · see citing works

Oxygen radicals and the nervous system

Halliwell, B. B., & Gutteridge, J. M. C. (1985) · Trends in Neurosciences · doi:10.1016/0166-2236(85)90010-4 · Cited by 822 · see citing works

Brain Regional Correspondence Between Alzheimer's Disease Histopathology and Biomarkers of Protein Oxidation

Hensley, K., Hall, N., Subramaniam, R., Cole, P., Harris, M., Aksenov, M., Aksenova, M., Gabbita, S. P., Wu, J. F., Carney, J. M., et al. (1995) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1995.65052146.x · Cited by 779 · see citing works

Flavonoids in Health and Disease

Rice-Evans, C. A., & Packer, L. (2003) · CRC Press eBooks · doi:10.1201/9780367803681 · Cited by 691 · see citing works

Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis

Drapeau, E., Mayo, W., Aurousseau, C., Moal, M. L., Piazza, P., & Abrous, D. N. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2334169100 · Cited by 657 · see citing works

Inflammation and neurodegeneration in Parkinson's disease

McGeer, P. L., & McGeer, E. G. (2004) · Parkinsonism & Related Disorders · doi:10.1016/j.parkreldis.2004.01.005 · Cited by 628 · see citing works

Glia and their cytokines in progression of neurodegeneration

Mrak, R. E., & Griffin, W. S. T. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.05.010 · Cited by 592 · see citing works

Antioxidant activities of flavonoids as bioactive components of food

Rice-Evans, C. A., & Miller, N. J. (1996) · Biochemical Society Transactions · doi:10.1042/bst0240790 · Cited by 584 · see citing works

Oxidative stress, cell cycle, and neurodegeneration

Klein, J. A., & Ackerman, S. L. (2003) · Journal of Clinical Investigation · doi:10.1172/jci18182 · Cited by 584 · see citing works

Micronutrients: oxidant/antioxidant status

Evans, P., & Halliwell, B. B. (2001) · British Journal Of Nutrition · doi:10.1079/bjn2000296 · Cited by 567 · see citing works

Ageing and the free radical theory

Wickens, A. P. (2001) · Respiration Physiology · doi:10.1016/s0034-5687(01)00313-9 · Cited by 560 · see citing works

Nitric oxide and oxygen radicals: a question of balance

Darley-Usmar, V. M., Wiseman, H., & Halliwell, B. B. (1995) · FEBS Letters · doi:10.1016/0014-5793(95)00764-z · Cited by 556 · see citing works

Flavonoids in Health and Disease

Rucker, R. B. (2004) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/79.5.891a · Cited by 555 · see citing works

Inflammation and the Degenerative Diseases of Aging

McGeer, P. L., & McGeer, E. G. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1332.007 · Cited by 519 · see citing works

Electrochemical Analysis of Protein Nitrotyrosine and Dityrosine in the Alzheimer Brain Indicates Region-Specific Accumulation

Hensley, K., Maidt, M. L., Yu, Z., Sang, H., Markesbery, W. R., & Floyd, R. A. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-20-08126.1998 · Cited by 508 · see citing works

Oxidative stress, cell cycle, and neurodegeneration

Klein, J. A., & Ackerman, S. L. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200318182 · Cited by 492 · see citing works

Role of oxidative stress and protein oxidation in the aging process1,2 1Guest Editor: Earl Stadtman 2This article is part of a series of reviews on “Oxidatively Modified Proteins in Aging and Disease.” The full list of papers may be found on the homepage of the journal.

Sohal, R. S. (2002) · Free Radical Biology and Medicine · doi:10.1016/s0891-5849(02)00856-0 · Cited by 477 · see citing works

Copper- and zinc-containing superoxide dismutase, manganese-containing superoxide dismutase, catalase, and glutathione peroxidase in normal and neoplastic human cell lines and normal human tissues.

Marklund, S. L., Westman, N. G., Lundgren, E., & Roos, G. (1982) · PubMed · Cited by 474 · see citing works

Inflammatory processes in Alzheimer's disease

McGeer, E. G., & McGeer, P. L. (2003) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/s0278-5846(03)00124-6 · Cited by 473 · see citing works

Knockout of ERK1 MAP Kinase Enhances Synaptic Plasticity in the Striatum and Facilitates Striatal-Mediated Learning and Memory

Mazzucchelli, C., Vantaggiato, C., Ciamei, A., Fasano, S., Pakhotin, P., Krezel, W., Welzl, H., Wolfer, D. P., Pagès, G., Valverde, O., et al. (2002) · Neuron · doi:10.1016/s0896-6273(02)00716-x · Cited by 456 · see citing works

Inflammation and Alzheimer's disease pathogenesis

Rogers, J., Webster, S. D., Lue, L., Brachova, L., CIVIN, W. H., Emmerling, M. R., Shivers, B. D., Walker, D. G., & McGeer, P. L. (1996) · Neurobiology of Aging · doi:10.1016/0197-4580(96)00115-7 · Cited by 441 · see citing works

Long-Term Dietary Strawberry, Spinach, or Vitamin E Supplementation Retards the Onset of Age-Related Neuronal Signal-Transduction and Cognitive Behavioral Deficits

Joseph, J. A., Shukitt‐Hale, B., Denisova, N. A., Prior, R. L., Cao, G., Martín, A., Taglialatela, G., & Bickford, P. C. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-19-08047.1998 · Cited by 432 · see citing works

Aging: Overview

Harman, D. (2001) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2001.tb05631.x · Cited by 416 · see citing works

Environmental stimulation of 129/SvJ mice causes increased cell proliferation and neurogenesis in the adult dentate gyrus

Kempermann, G., Brandon, E. P., & Gage, F. H. (1998) · Current Biology · doi:10.1016/s0960-9822(07)00377-6 · Cited by 385 · see citing works

An introduction to the free radical hypothesis in Parkinson's disease

Olanow, C. W. (1992) · Annals of Neurology · doi:10.1002/ana.410320703 · Cited by 382 · see citing works

Flavonoids and the brain: interactions at the blood–brain barrier and their physiological effects on the central nervous system

Youdim, K. A., Shukitt‐Hale, B., & Joseph, J. A. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2004.08.002 · Cited by 373 · see citing works

Reversing the deleterious effects of aging on neuronal communication and behavior: beneficial properties of fruit polyphenolic compounds

Joseph, J. A., Shukitt‐Hale, B., & Casadesús, G. (2005) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/81.1.313s · Cited by 368 · see citing works

Blueberry Supplementation Enhances Signaling and Prevents Behavioral Deficits in an Alzheimer Disease Model

Joseph, J. A., Arendash, G. W., Gordon, M. N., Diamond, D. M., Shukitt‐Hale, B., Morgan, D., & Denisova, N. A. (2003) · Nutritional Neuroscience · doi:10.1080/1028415031000111282 · Cited by 361 · see citing works

Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice

Sohal, R. S., Agarwal, S., Candas, M., Forster, M. J., & Lal, H. (1994) · Mechanisms of Ageing and Development · doi:10.1016/0047-6374(94)91595-4 · Cited by 346 · see citing works

A Necessity for MAP Kinase Activation in Mammalian Spatial Learning

Selcher, J. C., Atkins, C. M., Trzaskos, J. M., Paylor, R., & Sweatt, J. D. (1999) · Learning & Memory · doi:10.1101/lm.6.5.478 · Cited by 341 · see citing works

MAPK signaling in neurodegeneration: influences of flavonoids and of nitric oxide

Schroeter, H., BOYD, C., SPENCER, J., WILLIAMS, R., Cadenas, E., & Rice-Evans, C. A. (2002) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00075-1 · Cited by 338 · see citing works

Role of oxidative stress in neurodegeneration: recent developments in assay methods for oxidative stress and nutraceutical antioxidants

Cui, K., Luo, X., Xu, K., & Murthy, M. R. V. (2004) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2004.05.023 · Cited by 334 · see citing works

Aging and oxidative stress

Junqueira, V. B. C., Barros, S. B. D. M., Chan, S. S., Rodrigues, L., Giavarotti, L., Abud, R. L., & Deucher, G. P. (2004) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2004.02.003 · Cited by 329 · see citing works

A review of specific dietary antioxidants and the effects on biochemical mechanisms related to neurodegenerative processes

Esposito, E., Rotilio, D., DIMATTEO, V., Giulio, C. D., Cacchio, M., & Algeri, S. (2002) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00078-7 · Cited by 327 · see citing works

Modulation of Hippocampal Plasticity and Cognitive Behavior by Short-term Blueberry Supplementation in Aged Rats

Casadesús, G., Shukitt‐Hale, B., Stellwagen, H. M., Zhu, X., Lee, H., Smith, M. A., & Joseph, J. A. (2004) · Nutritional Neuroscience · doi:10.1080/10284150400020482 · Cited by 304 · see citing works

Patterns of Motor Impairment in Normal Aging, Mild Cognitive Decline, and Early Alzheimer' Disease

Kluger, A., Gianutsos, J. G., Golomb, J. B., Ferris, S. H., GEORGE, A. E., Franssen, E., & Reisberg, ‌. (1997) · The Journals of Gerontology Series B · doi:10.1093/geronb/52b.1.p28 · Cited by 304 · see citing works

Alzheimer's disease – synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts

Münch, G. W., Schinzel, R., Loske, C., Wong, A. O., Durany, N., Li, J. J., Vlassara, H., Smith, M. A., Perry, G. L., & Riederer, P. F. (1998) · Journal of Neural Transmission · doi:10.1007/s007020050069 · Cited by 302 · see citing works

Tumor Necrosis Factor Alpha-Induced Apoptosis in Human Neuronal Cells: Protection by the Antioxidant N-Acetylcysteine and the Genes bcl-2 and crmA

Talley, A. K., Dewhurst, S., Perry, S. W., Dollard, S. C., Gummuluru, S., Fine, S. M., New, D., Epstein, L. G., Gendelman, H. E., & Gelbard, H. A. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.5.2359 · Cited by 302 · see citing works

Can oxidative damage be treated nutritionally?

BERGER, M. (2005) · Clinical Nutrition · doi:10.1016/j.clnu.2004.10.003 · Cited by 276 · see citing works

Free‐Radical Theory of Aging

Harman, D. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb12069.x · Cited by 273 · see citing works

Autophagy, proteasomes, lipofuscin, and oxidative stress in the aging brain

Keller, J. N., Dimayuga, E. R., Chen, Q., Thorpe, J. A., Gee, J. R., & Ding, Q. (2004) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2004.05.003 · Cited by 271 · see citing works

Age-Related Activation of Microglia and Astrocytes: In Vitro Studies Show Persistent Phenotypes of Aging, Increased Proliferation, and Resistance to Down-Regulation

Rozovsky, I., Finch, C. E., & Morgan, T. E. (1998) · Neurobiology of Aging · doi:10.1016/s0197-4580(97)00169-3 · Cited by 254 · see citing works

Neurobehavioral aspects of antioxidants in aging

Cantuti‐Castelvetri, I., Shukitt‐Hale, B., & Joseph, J. A. (2000) · International Journal of Developmental Neuroscience · doi:10.1016/s0736-5748(00)00008-3 · Cited by 233 · see citing works

Dietary Flavonoids as Potential Neuroprotectants

Youdim, K. A., Spencer, J. P. E., Schroeter, H., & Rice-Evans, C. A. (2002) · Biological Chemistry · doi:10.1515/bc.2002.052 · Cited by 210 · see citing works

The role of complement and activated microglia in the pathogenesis of Alzheimer's disease

Eikelenboom, P., & Veerhuis, R. (1996) · Neurobiology of Aging · doi:10.1016/0197-4580(96)00108-x · Cited by 206 · see citing works

Fruit Polyphenolics and Brain Aging

Galli, R. L., Shukitt‐Hale, B., Youdim, K. A., & Joseph, J. A. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb02089.x · Cited by 199 · see citing works

Nutritional Antioxidants Mechanisms of Action, Analyses of Activities and Medical Applications

Vaya, J., & Aviram, M. (2001) · Current Medicinal Chemistry - Immunology Endocrine & Metabolic Agents · doi:10.2174/1568013013359168 · Cited by 196 · see citing works

Microglial Cell Activation in Aging and Alzheimer Disease: Partial Linkage with Neurofibrillary Tangle Burden in the Hippocampus

DIPATRE, P. L., & GELMAN, B. B. (1997) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-199702000-00004 · Cited by 157 · see citing works

Migration and synaptogenesis of cone photoreceptors in the developing mouse retina

Rich, K. A., Zhan, Y., & Blanks, J. C. (1997) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19971110)388:1 · Cited by 156 · see citing works

POOR NUTRITIONAL STATUS AND INFLAMMATION: Linking Oxidative Stress and Inflammation in Kidney Disease: Which is the Chicken and Which is the Egg?

Himmelfarb, J. (2004) · Seminars in Dialysis · doi:10.1111/j.0894-0959.2004.17605.x · Cited by 139 · see citing works

Cytokine-induced expression of vascular cell adhesion molecule-1 (VCAM-1) by astrocytes and astrocytoma cell lines.

Rosenman, S. J., Shrikant, P., Dubb, L., Benveniste, E. N., & Ransohoff, R. M. (1995) · The Journal of Immunology · doi:10.4049/jimmunol.154.4.1888 · Cited by 137 · see citing works

Cytokine production in the central nervous system

Woodroofe, M. N. (1995) · Neurology · doi:10.1212/wnl.45.6_suppl_6.s6 · Cited by 137 · see citing works

Protein kinases: which one is the memory molecule?

Micheau, J. (1999) · Cellular and Molecular Life Sciences · doi:10.1007/s000180050312 · Cited by 135 · see citing works

Age-related hippocampal changes in Bcl-2:Bax ratio, oxidative stress, redox-active iron and apoptosis associated with aluminum-induced neurodegeneration: increased susceptibility with aging.

Savory, J., Rao, J. K. S., Huang, Y., Letada, P. R., & Herman, M. M. (1999) · PubMed · Cited by 132 · see citing works

Psychomotor performance in the senescent rodent: reduction of deficits via striatal dopamine receptor up-regulation

Joseph, J. A., Bartus, R. T., Clody, D. E., Morgan, D., Finch, C. E., Beer, B., & Sesack, S. R. (1983) · Neurobiology of Aging · doi:10.1016/0197-4580(83)90008-8 · Cited by 130 · see citing works

A unifying view of ageing and disease: the double-agent theory

Lane, N. J. (2003) · Journal of Theoretical Biology · doi:10.1016/s0022-5193(03)00304-7 · Cited by 122 · see citing works

Stress-related diseases -- a potential role for nitric oxide.

Esch, T., Stefano, G. B., Fricchione, G. L., & Benson, H. (2002) · PubMed · Cited by 114 · see citing works

Inflammatory response in the elderly

Grimble, R. F. (2003) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/00075197-200301000-00005 · Cited by 105 · see citing works

Oxidative stress protection and vulnerability in aging: putative nutritional implications for intervention

Joseph, J. A., Denisova, N. A., Bielinski, D. F., Fisher, D. R., & Shukitt‐Hale, B. (2000) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(00)00128-7 · Cited by 104 · see citing works

Dose effect of oxidative stress on signal transduction in aging

Yoon, S.-O., Yun, C.-H., & Chung, A. (2002) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(02)00095-7 · Cited by 103 · see citing works

Tumor Necrosis Factor-Alpha in Normal and Diseased Brain: Conflicting Effects Via Intraneuronal Receptor Crosstalk?

Perry, S. W., Dewhurst, S., Bellizzi, M. J., & Gelbard, H. A. (2002) · Journal of NeuroVirology · doi:10.1080/13550280290101021 · Cited by 103 · see citing works

Investigations on oxidative stress and therapeutical implications in dementia

Durany, N., Münch, G. W., Michel, T. M., & Riederer, P. F. (1999) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/pl00014177 · Cited by 88 · see citing works

Drugs to Treat Age‐Related Neurodegenerative Problems The Final Frontier of Medical Science?

Bartus, R. T. (1990) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1990.tb01430.x · Cited by 87 · see citing works

Oxidative Stress in Neurodegeneration: Mechanisms and Therapeutic Perspectives

Contestabile, B. S. P. A. (2001) · Current Topics in Medicinal Chemistry · doi:10.2174/1568026013394723 · Cited by 83 · see citing works

Aging‐ and Oxygen‐induced Modifications in Brain Biochemistry and Behaviora

Carney, J. M., Smith, C. D., Carney, A. M., & Butterfield, D. A. (1994) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1994.tb21788.x · Cited by 79 · see citing works

Effects of fruits and vegetables on levels of vitamins E and C in the brain and their association with cognitive performance.

Martin-Marco, A., Cherubini, A., Andrés‐Lacueva, C., Paniagua, M. A., & Joseph, J. A. (2002) · PubMed · Cited by 77 · see citing works

Impacts of transcriptional regulation on aging and senescence

Roy, A. K., Oh, T., Rivera, O., Mubiru, J., Song, C. S., & Chatterjee, B. (2002) · Ageing Research Reviews · doi:10.1016/s1568-1637(02)00006-5 · Cited by 72 · see citing works

Membrane and Receptor Modifications of Oxidative Stress Vulnerability in Aging: Nutritional Considerations

Joseph, J. A., Denisova, N., FISHER, D., Shukitt‐Hale, B., Bickford, P. C., Prior, R. L., & Cao, G. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb09908.x · Cited by 62 · see citing works

Nutritional Neuroscience

Lieberman, H. R. (2006) · Nutrition Today · doi:10.1097/00017285-200603000-00010 · Cited by 53 · see citing works

Differential effects of protein kinase inhibitors and activators on memory formation in the 2-day-old chick

Serrano, P. A., Beniston, D. S., Oxonian, M. G., Rodriguez, W. A., Rosenzweig, M. R., & Bennett, E. L. (1994) · Behavioral and Neural Biology · doi:10.1016/s0163-1047(05)80045-7 · Cited by 50 · see citing works

Magnetic resonance microscopy of iron in the basal forebrain cholinergic structures of the aged mouse lemur

Gilissen, E., Jacobs, R. E., & Allman, J. M. (1999) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(99)00162-8 · Cited by 42 · see citing works

Inflammatory mechanisms and anti-inflammatory therapy in Alzheimer's disease

O’Banion, M. K., & Finch, C. E. (1996) · Neurobiology of Aging · doi:10.1016/0197-4580(96)00102-9 · Cited by 33 · see citing works

Topographical localization of lipofuscin pigment in the brain of the aged fat-tailed dwarf lemur(Cheirogaleus Medius) and grey lesser mouse lemur(Microcebus Murinus): Comparison to iron localization

Gilissen, E., Jacobs, R. E., McGuinness, E. R., & Allman, J. M. (1999) · American Journal of Primatology · doi:10.1002/(sici)1098-2345(199910)49:2 · Cited by 15 · see citing works

Parkinson's disease, Parkinsonism and aging

Nicita-Mauro, V., Basile, G., Mento, A., Epifanio, A., Martino, G., & Morgante, F. (2002) · Archives of Gerontology and Geriatrics · doi:10.1016/s0167-4943(02)00138-3 · Cited by 10 · see citing works

Phytocemicals in Foods and Beverages

Carey, A. N., Joseph, J. A., & Shukitt‐Hale, B. (2005) · Nutrition, brain, and behavior./Nutrition, brain and behavior · doi:10.1201/9780203564554.ch23 · Cited by 1 · see citing works

Studies on free radicals, antioxidants, and co-factors.

Rahman, K. (2007) · PubMed Central · Cited by 981 · see citing works

Dietary polyphenols: Good, bad, or indifferent for your health?

Halliwell, B. B. (2006) · Cardiovascular Research · doi:10.1016/j.cardiores.2006.10.004 · Cited by 558 · see citing works

Challenges for Research on Polyphenols from Foods in Alzheimer’s Disease: Bioavailability, Metabolism, and Cellular and Molecular Mechanisms

Singh, M., Arseneault, M., Sanderson, J. T., Murthy, V., & Ramassamy, C. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0735073 · Cited by 438 · see citing works

Mediterranean diet: The role of long-chain ω-3 fatty acids in fish; polyphenols in fruits, vegetables, cereals, coffee, tea, cacao and wine; probiotics and vitamins in prevention of stroke, age-related cognitive decline, and Alzheimer disease

Román, G. C., Jackson, R. E., Gadhia, R. R., Roman, A., & Reis, J. J. (2019) · Revue Neurologique · doi:10.1016/j.neurol.2019.08.005 · Cited by 422 · see citing works

Gene Expression and Metabolite Profiling of Developing Highbush Blueberry Fruit Indicates Transcriptional Regulation of Flavonoid Metabolism and Activation of Abscisic Acid Metabolism

Zifkin, M., Jin, A., Ozga, J. A., Zaharia, L. I., Schernthaner, J. P., Gesell, A., Abrams, S. R., Kennedy, J. A., & Constabel, C. P. (2011) · PLANT PHYSIOLOGY · doi:10.1104/pp.111.180950 · Cited by 318 · see citing works

Phytochemicals of Cranberries and Cranberry Products: Characterization, Potential Health Effects, and Processing Stability

Pappas, E. L., & Schaich, K. M. (2009) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408390802145377 · Cited by 301 · see citing works

Moderate consumption of Cabernet Sauvignon attenuates A� neuropathology in a mouse model of Alzheimer's disease

Wang, J., Ho, L., Zhao, Z., Seror, I., Humala, N., Dickstein, D. L., Thiyagarajan, M., Percival, S. S., Talcott, S. T., & Pasinetti, G. M. (2006) · The FASEB Journal · doi:10.1096/fj.06-6281com · Cited by 299 · see citing works

Curcumin inhibits aggregation of α-synuclein

Pandey, N., Strider, J., Nolan, W. C., Yan, S. X., & Galvin, J. E. (2008) · Acta Neuropathologica · doi:10.1007/s00401-007-0332-4 · Cited by 265 · see citing works

Role of Nitric Oxide Synthases in Parkinson’s Disease: A Review on the Antioxidant and Anti-inflammatory Activity of Polyphenols

Aquilano, K., Baldelli, S., Rotilio, G., & Ciriolo, M. R. (2008) · Neurochemical Research · doi:10.1007/s11064-008-9697-6 · Cited by 267 · see citing works

Neuroprotective molecular mechanisms of (−)-epigallocatechin-3-gallate: a reflective outcome of its antioxidant, iron chelating and neuritogenic properties

Weinreb, O., Amit, T., Mandel, S. A., & Youdim, M. B. H. (2009) · Genes & Nutrition · doi:10.1007/s12263-009-0143-4 · Cited by 244 · see citing works

Inhibitory effects of blueberry extract on the production of inflammatory mediators in lipopolysaccharide‐activated BV2 microglia

Lau, F. C., Bielinski, D. F., & Joseph, J. A. (2007) · Journal of Neuroscience Research · doi:10.1002/jnr.21205 · Cited by 221 · see citing works

Consumption of Grape Seed Extract Prevents Amyloid-β Deposition and Attenuates Inflammation in Brain of an Alzheimer’s Disease Mouse

Wang, Y., Thomas, P., Zhong, J., Bi, F., Kosaraju, S. L., Pollard, A., Fenech, M. F., & Zhou, X. (2009) · Neurotoxicity Research · doi:10.1007/s12640-009-9000-x · Cited by 221 · see citing works

Berberine and neurodegeneration: A review of literature

Ahmed, T., Gilani, A. H., Abdollahi, M. R., Daglia, M., Nabavi, S. F., & Nabavi, S. M. (2015) · Pharmacological Reports · doi:10.1016/j.pharep.2015.03.002 · Cited by 210 · see citing works

Purple Corn ( <i>Zea mays</i> L.) Phenolic Compounds Profile and Its Assessment as an Agent Against Oxidative Stress in Isolated Mouse Organs

Ramos-Escudero, F., Muñoz, A. M., Alvarado-Ortíz, C., Alvarado, Á., & Yáñez, J. A. (2012) · Journal of Medicinal Food · doi:10.1089/jmf.2010.0342 · Cited by 204 · see citing works

Flavonoids and cognitive function: a review of human randomized controlled trial studies and recommendations for future studies

Macready, A. L., Kennedy, O. B., Ellis, J. A., Williams, C. M., Spencer, J. P. E., & Butler, L. T. (2009) · Genes & Nutrition · doi:10.1007/s12263-009-0135-4 · Cited by 198 · see citing works

BHT Blocks NF‐κB activation and Ethanol‐Induced Brain Damage

Crews, F. T., Nixon, K., Kim, D., Joseph, J. A., Shukitt‐Hale, B., Qin, L., & Zou, J. (2006) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2006.00239.x · Cited by 184 · see citing works

Do polyphenols enter the brain and does it matter? Some theoretical and practical considerations

Schaffer, S., & Halliwell, B. (2012) · Genes &amp; Nutrition · doi:10.1007/s12263-011-0255-5 · Cited by 178 · see citing works

Evaluation of Polyphenol Anthocyanin-Enriched Extracts of Blackberry, Black Raspberry, Blueberry, Cranberry, Red Raspberry, and Strawberry for Free Radical Scavenging, Reactive Carbonyl Species Trapping, Anti-Glycation, Anti-β-Amyloid Aggregation, and Microglial Neuroprotective Effects

Ma, H., Johnson, S. L., Liu, W., DaSilva, N. A., Meschwitz, S. M., Dain, J. A., & Seeram, N. P. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19020461 · Cited by 179 · see citing works

Neuroprotective effects of berry fruits on neurodegenerative diseases

Essa, M. M., Subash, S., Al‐Adawi, S., Memon, M. A., Manivasagam, T., & Akbar, M. D. (2014) · Neural Regeneration Research · doi:10.4103/1673-5374.139483 · Cited by 172 · see citing works

Peripheral and Central Effects of Melatonin on Blood Pressure Regulation

Pecháňová, O., Paulis, L., & Šimko, F. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms151017920 · Cited by 158 · see citing works

Metabolic syndrome and the role of dietary lifestyles in Alzheimer’s disease

Pasinetti, G. M., & Eberstein, J. A. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05454.x · Cited by 157 · see citing works

The endocannabinoid system in normal and pathological brain ageing

Bilkei‐Gorzó, A. (2012) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2011.0388 · Cited by 157 · see citing works

Effects of Resveratrol and other Polyphenols on Sirt1: Relevance to Brain Function During Aging

Sarubbo, F., Esteban, S., Miralles, A., & Moranta, D. (2017) · Current Neuropharmacology · doi:10.2174/1570159x15666170703113212 · Cited by 144 · see citing works

The Contribution of Fruit and Vegetable Consumption to Human Health

Yahia, E. M. (2009) · Wiley eBooks · doi:10.1002/9780813809397.ch1 · Cited by 136 · see citing works

Neuroprotective effects of anthocyanins and their in vivo metabolites in SH-SY5Y cells

Tarozzi, A., Morroni, F., Hrelia, S., Angeloni, C., Marchesi, A., Cantelli‐Forti, G., & Hrelia, P. (2007) · Neuroscience Letters · doi:10.1016/j.neulet.2007.07.017 · Cited by 135 · see citing works

Clinical oxidation parameters of aging

Voß, P., & Siems, W. (2006) · Free Radical Research · doi:10.1080/10715760600953859 · Cited by 134 · see citing works

Antimicrobial effect of blueberry (Vaccinium corymbosum L.) extracts against the growth of Listeria monocytogenes and Salmonella Enteritidis

Shen, X., Sun, X., Xie, Q., Liu, H., Zhao, Y., Pan, Y., Hwang, C., & Wu, V. C. H. (2013) · Food Control · doi:10.1016/j.foodcont.2013.06.040 · Cited by 137 · see citing works

Reactive oxygen species, dietary restriction and neurotrophic factors in age‐related loss of myenteric neurons

Thrasivoulou, C., Soubeyre, V., Ridha, H., Giuliani, D., Giaroni, C., Michael, G. J., Saffrey, M. J., & Cowen, T. (2006) · Aging Cell · doi:10.1111/j.1474-9726.2006.00214.x · Cited by 132 · see citing works

Nutrition, Inflammation, and Cognitive Function

Wärnberǵ, J., Gómez‐Martínez, S., Romeo, J., Díaz, L. E., & Marcos, A. (2009) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2008.03985.x · Cited by 131 · see citing works

Neurological Effects of Honey: Current and Future Prospects

Rahman, M. M., Gan, S. H., & Khalil, M. I. (2014) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2014/958721 · Cited by 128 · see citing works

A blueberry-enriched diet provides cellular protection against oxidative stress and reduces a kainate-induced learning impairment in rats

Duffy, K. B., Spangler, E. L., Devan, B. D., Guo, Z., Bowker, J. L., Janas, A. M., Hagepanos, A., Minor, R. K., de Cabo, R., Mouton, P. R., et al. (2007) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2007.04.002 · Cited by 124 · see citing works

Multi-Target Mechanisms of Phytochemicals in Alzheimer’s Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation

Sharifi-Rad, J., Rapposelli, S., Sestito, S., Herrera-Bravo, J., Arancibia-Diaz, A., Salazar, L. A., Yeskaliyeva, B., Beyatli, A., Leyva-Gómez, G., González-Contreras, C., et al. (2022) · Journal of Personalized Medicine · doi:10.3390/jpm12091515 · Cited by 125 · see citing works

Dietary fatty acids in dementia and predementia syndromes: Epidemiological evidence and possible underlying mechanisms

Solfrizzi, V., Frisardi, V., Capurso, C. A., D’Introno, A., Colacicco, A. M., Vendemiale, G., Capurso, A., & Panza, F. (2009) · Ageing Research Reviews · doi:10.1016/j.arr.2009.07.005 · Cited by 120 · see citing works

Orange fibre as potential functional ingredient for dry-cured sausages

Fernández‐López, J., Viuda‐Martos, M., Sendra, E., Sayas‐Barberá, E., Navarro, C., & Pérez‐Álvarez, J. Á. (2006) · European Food Research and Technology · doi:10.1007/s00217-006-0501-z · Cited by 116 · see citing works

Peach ( Prunus Persica ): Phytochemicals and Health Benefits

Bento, C., Gonçalves, A. C., Silva, B. M., & Silva, L. R. (2020) · Food Reviews International · doi:10.1080/87559129.2020.1837861 · Cited by 121 · see citing works

Berry anthocyanins and their aglycons inhibit monoamine oxidases A and B

Dreiseitel, A., Korte, G., Schreier, P. H., Oehme, A., Locher, S., Domani, M., Hajak, G., & Sand, P. G. (2009) · Pharmacological Research · doi:10.1016/j.phrs.2009.01.014 · Cited by 104 · see citing works

Modulation of cognition and behavior in aged animals: role for antioxidant- and essential fatty acid–rich plant foods

Willis, L., Shukitt‐Hale, B., & Joseph, J. A. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.26736j · Cited by 105 · see citing works

Green synthesis of silver nanoparticles using Trapa natans extract and their anticancer activity against A431 human skin cancer cells

Saber, M. M., Mirtajani, S. B., & Karimzadeh, K. (2018) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2018.08.004 · Cited by 97 · see citing works

Activation of glutathione peroxidase via Nrf1 mediates genistein’s protection against oxidative endothelial cell injury

Hernandez-Montes, E., Pollard, S. E., Vauzour, D., Jofre‐Monseny, L., Rota, C., Rimbach, G. H., Weinberg, P. D., & Spencer, J. P. E. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.05.197 · Cited by 96 · see citing works

Reaction time and DPPH concentration influence antioxidant activity and kinetic parameters of bioactive molecules and plant extracts in the reaction with the DPPH radical

Fadda, A., Serra, M., Molinu, M. G., Azara, E., Barberis, A., & Sanna, D. (2014) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2014.06.006 · Cited by 94 · see citing works

Effects of long-term administration of a cocoa polyphenolic extract (Acticoa powder) on cognitive performances in aged rats

Bisson, J., Nejdi, A., Rozan, P., Hidalgo, S., Lalonde, R., & Messaoudi, M. (2008) · British Journal Of Nutrition · doi:10.1017/s0007114507886375 · Cited by 90 · see citing works

The Advances in Neurobiology

Ishwarya, M., & Narendhirakannan, R. T. (2016) · Advances in neurobiology · doi:10.1007/978-3-319-28383-8_15 · Cited by 91 · see citing works

Pomegranate ellagitannin-gut microbial-derived metabolites, urolithins, inhibit neuroinflammation in vitro

DaSilva, N. A., Nahar, P. P., Ma, H., Eid, A., Wei, Z., Meschwitz, S. M., Zawia, N. H., Slitt, A. L., & Seeram, N. P. (2017) · Nutritional Neuroscience · doi:10.1080/1028415x.2017.1360558 · Cited by 94 · see citing works

Dietary Berries and Ellagic Acid Diminish Estrogen-Mediated Mammary Tumorigenesis ∈ ACI rats

Aiyer, H. S., Srinivasan, C., & Gupta, R. C. (2008) · Nutrition and Cancer · doi:10.1080/01635580701624712 · Cited by 90 · see citing works

Attenuation of oxidative stress, neuroinflammation, and apoptosis by curcumin prevents cognitive deficits in rats postnatally exposed to ethanol

Tiwari, V., & Chopra, K. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2779-9 · Cited by 85 · see citing works

Neuroprotective Effects of Bikaverin on H2O2-Induced Oxidative Stress Mediated Neuronal Damage in SH-SY5Y Cell Line

Nırmaladevı, D., Venkataramana, M., Chandranayaka, S., Ramesha, A., Jameel, N. M., & Srinivas, C. (2014) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-014-0073-6 · Cited by 85 · see citing works

Metabolism, mood and cognition in aging: the importance of lifestyle and dietary intervention

Hendrickx, H., McEwen, B. S., & Ouderaa, F. V. D. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.10.005 · Cited by 83 · see citing works

Isolation, antioxidant property and protective effect on PC12 cell of the main anthocyanin in fruit of Lycium ruthenicum Murray

Tang, J., Yan, Y., Ran, L., Mi, J., Sun, Y., Lu, L., Gao, Y., Zeng, X., & Cao, Y. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.01.015 · Cited by 83 · see citing works

Omics Technologies to Enhance Plant Based Functional Foods: An Overview

Nayak, S. N., Aravind, B., Malavalli, S. S., Sukanth, B. S., Poornima, R., Bharati, P., Hefferon, K. L., Kole, C., & Puppala, N. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.742095 · Cited by 83 · see citing works

The Influence of Gut Microbiota on Neurogenesis: Evidence and Hopes

Sarubbo, F., Cavallucci, V., & Pani, G. (2022) · Cells · doi:10.3390/cells11030382 · Cited by 82 · see citing works

Superparamagnetic iron oxide nanoparticles combined with NGF and quercetin promote neuronal branching morphogenesis of PC12 cells

Katebi, S., Esmaeili, A., Ghaedi, K., & Zarrabi, A. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s191878 · Cited by 79 · see citing works

Dietary polyphenols and neurogenesis: Molecular interactions and implication for brain ageing and cognition

Sarubbo, F., Moranta, D., & Pani, G. (2018) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2018.05.011 · Cited by 77 · see citing works

Curcumin protects mouse neuroblastoma Neuro-2A cells against hydrogen-peroxide-induced oxidative stress

Zhao, X., Zhang, L., Yu, H., Sun, Z., Lin, X., Tan, C., & Lu, R. (2011) · Food Chemistry · doi:10.1016/j.foodchem.2011.04.089 · Cited by 76 · see citing works

Antioxidant and neuroprotective properties of blueberry polyphenols: a critical review

Giacalone, M., Sacco, F. D., Traupe, I., Topini, R., Forfori, F., & Giunta, F. (2011) · Nutritional Neuroscience · doi:10.1179/1476830511y.0000000007 · Cited by 75 · see citing works

Determination of Post-Harvest Biochemical Composition, Enzymatic Activities, and Oxidative Browning in 14 Apple Cultivars

Serra, S., Anthony, B. M., Sesillo, F. B., Masia, A., & Musacchi, S. (2021) · Foods · doi:10.3390/foods10010186 · Cited by 72 · see citing works

Natural Compounds and Plant Extracts as Therapeutics Against Chronic Inflammation in Alzheimer’s Disease – A Translational Perspective

Apetz, N., Münch, G. W., Govindaraghavan, S., & Gyengési, E. (2014) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527313666140917110635 · Cited by 72 · see citing works

Blueberry Supplementation Improves Memory in Middle-Aged Mice Fed a High-Fat Diet

Carey, A. N., Gomes, S. M., & Shukitt‐Hale, B. (2014) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf404565s · Cited by 71 · see citing works

Antioxidant and antiproliferative activity of polyphenols in novel high-polyphenol grape lines

Jacob, J. K., Hakimuddin, F., Paliyath, G., & Fisher, H. (2008) · Food Research International · doi:10.1016/j.foodres.2008.02.009 · Cited by 70 · see citing works

Hesperidin, a Flavone Glycoside, as Mediator of Neuronal Survival

Nones, J., Spohr, T. C. L. D. S. E., & Gomes, F. C. A. (2011) · Neurochemical Research · doi:10.1007/s11064-011-0493-3 · Cited by 69 · see citing works

Quercetin attenuates spontaneous behavior and spatial memory impairment in d-galactose–treated mice by increasing brain antioxidant capacity

Sun, S. W., Yu, H. Q., Zhang, H., Zheng, Y. L., Wang, J. J., & Luo, L. (2007) · Nutrition Research · doi:10.1016/j.nutres.2007.01.010 · Cited by 62 · see citing works

Chemical Analysis and Effect of Blueberry and Lingonberry Fruits and Leaves against Glutamate-Mediated Excitotoxicity

Vyas, P., Kalidindi, S., Chibrikova, L., Igamberdiev, A. U., & Weber, J. T. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf401158a · Cited by 70 · see citing works

Antioxidant Potential of Chestnut (Castanea sativa L.) and Almond (Prunus dulcis L.) By-products

Barreira, J. C. M., Ferreira, I. C. F. R., Oliveira, M. B. P. P., & Pereira, J. A. (2010) · Food Science and Technology International · doi:10.1177/1082013209353983 · Cited by 66 · see citing works

Effects of thymol on amyloid-β-induced impairments in hippocampal synaptic plasticity in rats fed a high-fat diet

Asadbegi, M., Komaki‬, A., Salehi, I., Yaghmaei, P., Ebrahim‐Habibi, A., Shahidi, ‬., Sarihi, A., Asl, S. S., & Golipoor, Z. (2018) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2018.01.008 · Cited by 65 · see citing works

Protective effects of blueberries (Vaccinium corymbosum L.) extract against cadmium-induced hepatotoxicity in mice

Gong, P., Chen, F., Wang, L., Wang, J., Jin, S., & Ma, Y. (2014) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2014.03.017 · Cited by 63 · see citing works

Oral Supplements of Aqueous Extract of Tomato Seeds Alleviate Motor Abnormality, Oxidative Impairments and Neurotoxicity Induced by Rotenone in Mice: Relevance to Parkinson’s Disease

Krishna, G., & ., M. (2014) · Neurochemical Research · doi:10.1007/s11064-014-1323-1 · Cited by 61 · see citing works

Biochemical deficits and cognitive decline in brain aging: Intervention by dietary supplements

Poddar, J., Pradhan, M., Ganguly, G., & Chakrabarti, S. (2018) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2018.04.002 · Cited by 62 · see citing works

Chronic green tea consumption prevents age-related changes in rat hippocampal formation

Assunção, M., Santos‐Marques, M. J., Carvalho, F. D., Lukoyanov, N., & Andrade, J. P. (2009) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.03.016 · Cited by 60 · see citing works

Attenuation of iNOS and COX2 by blueberry polyphenols is mediated through the suppression of NF-κB activation

Lau, F. C., Joseph, J. A., McDonald, J. E., & Kalt, W. (2009) · Journal of Functional Foods · doi:10.1016/j.jff.2009.05.001 · Cited by 60 · see citing works

Piceatannol attenuates hydrogen-peroxide- and peroxynitrite-induced apoptosis of PC12 cells by blocking down-regulation of Bcl-XL and activation of JNK

Kim, H. J., Lee, K. W., Kim, M.-S., & Lee, H. J. (2007) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2007.06.001 · Cited by 60 · see citing works

Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model

Park, J.-Y., Kim, Y.-H., Im, J. A., & Lee, H. (2015) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-015-0709-1 · Cited by 57 · see citing works

Inhibition of proteasome activity by anthocyanins and anthocyanidins

Dreiseitel, A., Schreier, P. H., Oehme, A., Locher, S., Rogler, G., Piberger, H., Hajak, G., & Sand, P. G. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.04.140 · Cited by 56 · see citing works

Diversity of anthocyanins and other phenolic compounds among tropical root crops from Vanuatu, South Pacific

Champagne, A., Hilbert, G., Legendre, L., & Lebot, V. (2011) · Journal of Food Composition and Analysis · doi:10.1016/j.jfca.2010.12.004 · Cited by 54 · see citing works

Chronic green tea catechins administration prevents oxidative stress-related brain aging in C57BL/6J mice

Li, Q., Zhao, H., Zhao, M., Zhang, Z., & Li, Y. (2010) · Brain Research · doi:10.1016/j.brainres.2010.07.074 · Cited by 53 · see citing works

Local Mediterranean Food Plants and Nutraceuticals

(2006) · Forum of nutrition/Bibliotheca Nutritio et dieta · doi:10.1159/isbn.978-3-318-01352-8 · Cited by 53 · see citing works

Anti-Angiogenic Functional and Medicinal Foods

Losso, J. N., Shahidi, F., & Bagchi, D. (2007) · CRC Press eBooks · doi:10.1201/9781420015584 · Cited by 53 · see citing works

Aging of the rat mesostriatal system: Differences between the nigrostriatal and the mesolimbic compartments

Cruz‐Muros, I., Afonso‐Oramas, D., Abreu, P. M., Barroso‐Chinea, P., Rodrı́guez, M., González, M. C., & González‐Hernández, T. (2006) · Experimental Neurology · doi:10.1016/j.expneurol.2006.10.004 · Cited by 52 · see citing works

Differential Protection among Fractionated Blueberry Polyphenolic Families against DA-, Aβ42- and LPS-Induced Decrements in Ca2+ Buffering in Primary Hippocampal Cells

Joseph, J. A., Shukitt‐Hale, B., Brewer, G. J., Weikel, K., Kalt, W., & Fisher, D. R. (2010) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf100144y · Cited by 51 · see citing works

Synaptic failure and adenosine triphosphate imbalance induced by amyloid‐β aggregates are prevented by blueberry‐enriched polyphenols extract

Fuentealba, J., Dibarrart, A. J., Fuentes-Fuentes, M. C., Sáez-Orellana, F., Quiñones, K., Guzmán, L., Pérez, C. I., Becerra, J., & Aguayo, L. G. (2011) · Journal of Neuroscience Research · doi:10.1002/jnr.22679 · Cited by 49 · see citing works

Brain Alterations in High Fat Diet Induced Obesity: Effects of Tart Cherry Seeds and Juice

Bonaventura, M. V. M. D., Martinelli, I., Moruzzi, M., Bonaventura, E. M. D., Giusepponi, M. E., Polidori, C., Lupidi, G., Tayebati, S. K., Amenta, F., Cifani, C., et al. (2020) · Nutrients · doi:10.3390/nu12030623 · Cited by 48 · see citing works

Green tea catechins decrease oxidative stress in surgical menopause‐induced overactive bladder in a rat model

Juan, Y., Chuang, S., Lee, Y., Long, C., Wu, T., Chang, W., Levin, R. M., Liu, K., & Huang, C. (2012) · British Journal of Urology · doi:10.1111/j.1464-410x.2012.11258.x · Cited by 47 · see citing works

Satiety in rats following blueberry extract consumption induced by appetite-suppressing mechanisms unrelated to in vitro or in vivo antioxidant capacity

Molan, A. L., Lila, M. A., & Mawson, A. J. (2007) · Food Chemistry · doi:10.1016/j.foodchem.2007.09.018 · Cited by 45 · see citing works

Hepatoprotective and Antioxidant Potential of Organic and Conventional Grape Juices in Rats Fed a High-Fat Diet

Buchner, I., Medeiros, N. D. S., Lacerda, D. D. S., Normann, C. A. B. M., Gemelli, T., Rigon, P., Wannmacher, C. M. D., Henriques, J. A. P., Dani, C., & Funchal, C. (2014) · Antioxidants · doi:10.3390/antiox3020323 · Cited by 45 · see citing works

Determination of Biochemical Composition in Peach (Prunus persica L. Batsch) Accessions Characterized by Different Flesh Color and Textural Typologies

Serra, S., Anthony, B. M., Masia, A., Giovannini, D., & Musacchi, S. (2020) · Foods · doi:10.3390/foods9101452 · Cited by 45 · see citing works

Anthocyanins: Are They Beneficial in Treating Ethanol Neurotoxicity?

Chen, G., & Luo, J. (2009) · Neurotoxicity Research · doi:10.1007/s12640-009-9083-4 · Cited by 44 · see citing works

Neurite Outgrowth and Neuroprotective Effects of Quercetin fromCaesalpinia mimosoidesLamk. on Cultured P19-Derived Neurons

Tangsaengvit, N., Kitphati, W., Tadtong, S., Bunyapraphatsara, N., & Nukoolkarn, V. S. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/838051 · Cited by 44 · see citing works

Impact of Gut Microbiota in Brain Ageing: Polyphenols as Beneficial Modulators

Sarubbo, F., Moranta, D., Tejada, S., Jiménez-García, M., & Esteban, S. (2023) · Antioxidants · doi:10.3390/antiox12040812 · Cited by 44 · see citing works

Influence of gamma irradiation in the antioxidant potential of chestnuts (Castanea sativa Mill.) fruits and skins

António, A. L., Fernandes, Â. S. F., Barreira, J. C. M., Bento, A. A., Botelho, M. L., & Ferreira, I. C. F. R. (2011) · Food and Chemical Toxicology · doi:10.1016/j.fct.2011.02.016 · Cited by 42 · see citing works

Plant polyphenols in cell-cell interaction and communication

Tarahovsky, Y. S. (2008) · Plant Signaling & Behavior · doi:10.4161/psb.3.8.6359 · Cited by 42 · see citing works

POTENTIAL OF SELECT YOGURTS FOR DIABETES AND HYPERTENSION MANAGEMENT

Apostolidis, E., Kwon, Y., & Shetty, K. (2006) · Journal of Food Biochemistry · doi:10.1111/j.1745-4514.2006.00091.x · Cited by 42 · see citing works

Synergistic effects of diet and exercise on hippocampal function in chronically stressed mice

Hutton, C. P., Déry, N., Rosa, E., Lemon, J. A., Rollo, C. D., Boreham, D. R., Fahnestock, M., deCatanzaro, D., Wojtowicz, J. M., & Becker, S. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.09.005 · Cited by 41 · see citing works

Effects of the flavonoid casticin from Brazilian Croton betulaster in cerebral cortical progenitors in vitro: Direct and indirect action through astrocytes

Spohr, T. C. L. D. S. E., Stipursky, J., Sasaki, A. C., Barbosa, P. R., Martins, V., Benjamim, C. F., Roque, N. F., Costa, S. L., & Gomes, F. C. A. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.22218 · Cited by 40 · see citing works

Beta-Cryptoxanthin, Plentiful in Japanese Mandarin Orange, Prevents Age-Related Cognitive Dysfunction and Oxidative Damage in Senescence-Accelerated Mouse Brain

Unno, K., Sugiura, M., Ogawa, K., Takabayashi, F., Toda, M., Sakuma, M., Maeda, K.-I., Fujitani, K., Miyazaki, H., Yamamoto, H., et al. (2011) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.34.311 · Cited by 39 · see citing works

Antioxidant markers based TLC-DPPH differentiation on four commercialized botanical sources of Shankhpushpi (A Medhya Rasayana): A preliminary assessment

Sethiya, N. K., Raja, M. K. M. M., & Mishra, S. (2013) · Journal of Advanced Pharmaceutical Technology amp Research · doi:10.4103/2231-4040.107497 · Cited by 40 · see citing works

The Contribution of Fruit and Vegetable Consumption to Human Health

Yahia, E. M., Celis, M. E. M., & Svendsen, M. (2017) · Wiley eBooks · doi:10.1002/9781119158042.ch1 · Cited by 43 · see citing works

A high-cholesterol diet enriched with polyphenols from Oriental plums (Prunus salicina) improves cognitive function and lowers brain cholesterol levels and neurodegenerative-related protein expression in mice

Kuo, P.-H., Lin, C.-I., Chen, Y., Chiu, W., & Lin, S. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114515000732 · Cited by 38 · see citing works

Synaptic Silencing and Plasma Membrane Dyshomeostasis Induced by Amyloid-β Peptide are Prevented by Aristotelia chilensis Enriched Extract

Fuentealba, J., Dibarrart, A. J., Sáez-Orellana, F., Fuentes-Fuentes, M. C., Oyanedel, C. N., Guzmán, J., Pérez, C. I., Becerra, J., & Aguayo, L. G. (2012) · Journal of Alzheimer s Disease · doi:10.3233/jad-2012-120229 · Cited by 37 · see citing works

Glutathione production is regulated via distinct pathways in stressed and non-stressed cortical neurons

Burdo, J. R., Schubert, D. A., & Maher, P. A. (2007) · Brain Research · doi:10.1016/j.brainres.2007.10.077 · Cited by 37 · see citing works

Flavonoids and Astrocytes Crosstalking: Implications for Brain Development and Pathology

Nones, J., Stipursky, J., Costa, S., & Gomes, F. (2010) · Neurochemical Research · doi:10.1007/s11064-010-0144-0 · Cited by 37 · see citing works

Antioxidant and Antigenotoxic Activities of Purple Grape Juice—Organic and Conventional—in Adult Rats

Dani, C., Oliboni, L. S., Umezu, F. M., Pasquali, M. A. D. B., Salvador, M. M., Moreira, J. C. F., & Henriques, J. A. P. (2009) · Journal of Medicinal Food · doi:10.1089/jmf.2008.0256 · Cited by 36 · see citing works

Pomegranate Supplementation Improves Affective and Motor Behavior in Mice after Radiation Exposure

Dulcich, M. S., & Hartman, R. E. (2013) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2013/940830 · Cited by 36 · see citing works

Blueberry Polyphenols and Neuroprotection

Giacalone, M., Sacco, F. D., Traupe, I., Pagnucci, N., Forfori, F., & Giunta, F. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-411462-3.00002-3 · Cited by 20 · see citing works

Fruit Polyphenolics and Brain Aging

Galli, R. L., Shukitt‐Hale, B., Youdim, K. A., & Joseph, J. A. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb02089.x · Cited by 199 · see citing works

Berry Fruit Supplementation and the Aging Brain

Shukitt‐Hale, B., Lau, F. C., & Joseph, J. A. (2008) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf072505f · Cited by 218 · see citing works

Blueberries and Neuronal Aging

Shukitt‐Hale, B. (2012) · Gerontology · doi:10.1159/000341101 · Cited by 44 · see citing works

Nutritional intervention in brain aging: reducing the effects of inflammation and oxidative stress.

Lau, F. C., Shukitt‐Hale, B., & Joseph, J. A. (2007) · PubMed · Cited by 100 · see citing works