Cited by 249Attention Deficit Hyperactivity DisorderNeurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

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Brain dopamine transporter levels in treatment and drug naive adults with ADHD

Volkow, Nora D., Wang, Gene-Jack, Newcorn, Jeffrey, Fowler, Joanna S., Telang, Frank, Solanto, Mary V., Logan, Jean, Wong, Christopher, Ma, Yeming, Swanson, James M., Schulz, Kurt, Pradhan, Kith·2007·NeuroImage

DOI 10.1016/j.neuroimage.2006.10.014

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Abstract

Attention deficit hyperactivity disorder (ADHD) is the most frequent psychiatric disorder in children, yet data are sparse on its pathophysiology. Particularly relevant are the dopamine transporters since these are the main targets of stimulant medications used for ADHD treatment. Though some imaging studies have shown increases in dopamine transporters in ADHD others have not and their role in the neurobiology of ADHD remains unclear. Here we investigate dopamine transporters in ADHD subjects with control of potentially confounding factors (previous medication and/or drug histories, comorbidity) and their association with clinical symptoms. Positron emission tomography and [11C]cocaine were used to measure dopamine transporters in 20 never medicated adults with ADHD and 25 controls. Dopamine transporters were lower in left caudate (13%, p < 0.05) and in left nucleus accumbens (p < 0.005) in ADHD subjects than in controls. In putamen dopamine transporters did not differ between groups but were associated with scores of inattention (Conners Adult Attention Rating Scale) both in ADHD subjects (p < 0.005) and in controls (p < 0.005). Thus, for a given transporter level the scores for inattention were on average five times greater in ADHD subjects than in controls. These results do not corroborate increases in dopamine transporters in ADHD subjects and show that in some they are reduced. It also provides evidence that dopamine transporter levels modulate attention but suggest that additional pathology (e.g., prefrontal or cingulostriatal pathways, noradrenergic neurotransmission) is necessary to account for the large differences in inattention observed between controls and ADHD subjects.

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A rating scale for depression
Hamilton, M. (1960) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.23.1.56 · Cited by 32,817
Co-Planar Stereotaxic Atlas of the Human Brain
Talairach, J., & Tournoux, P. (1988) · Medical Entomology and Zoology · Cited by 11,798
The assessment of anxiety states by rating
HAMILTON, M. (1959) · British Journal of Medical Psychology · doi:10.1111/j.2044-8341.1959.tb00467.x · Cited by 11,455
Statistical parametric maps in functional imaging: A general linear approach
Friston, K. J., Holmes, A. P., Worsley, K. J., Poline, J. ‐., Frith, C. D., & Frackowiak, R. S. J. (1994) · Human Brain Mapping · doi:10.1002/hbm.460020402 · Cited by 9,688
Co-planar stereotaxic atlas of the human brain
Laitinen, L. (1989) · Clinical Neurology and Neurosurgery · doi:10.1016/0303-8467(89)90128-5 · Cited by 7,565
Neuroscience of attention-deficit/hyperactivity disorder: the search for endophenotypes
Castellanos, F. X., & Tannock, R. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn896 · Cited by 1,827 · cited 1×
“However, other factors such as ADHD subtypes or genotypes may also affect DAT (Castellanos and Tannock, 2002; Pliszka et al., 1996).”
Background
Age-dependent decline of symptoms of attention deficit hyperactivity disorder: impact of remission definition and symptom type
Biederman, J. (2000) · American Journal of Psychiatry · doi:10.1176/appi.ajp.157.5.816 · Cited by 1,498
Graphical Analysis of Reversible Radioligand Binding from Time—Activity Measurements Applied to [ N - 11 C-Methyl]-(−)-Cocaine PET Studies in Human Subjects
Logan, J., Fowler, J. S., Volkow, N. D., Wolf, A. P., Dewey, S. L., Schlyer, D. J., MacGregor, R. R., HITZEMANN, R. J., Bendriem, B., Gatley, S. J., et al. (1990) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1990.127 · Cited by 1,481
Self-citation
Quantitative brain magnetic resonance imaging in attention-deficit hyperactivity disorder
Castellanos, F. X. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830070053009 · Cited by 1,183
a dynamic developmental theory of attention-deficit/hyperactivity disorder (adhd) predominantly hyperactive/impulsive and combined subtypes
sagvolden, T., johansen, E. B., aase, H., & russell, V. A. (2005) · Behavioral and Brain Sciences · doi:10.1017/s0140525x05000075 · Cited by 1,035
Impulsive choice induced in rats by lesions of the nucleus accumbens core
Cardinal, R. N., Pennicott, D. R., Lakmali, C., Sugathapala, Robbins, T. W., & Everitt, B. J. (2001) · Science · doi:10.1126/science.1060818 · Cited by 923
Correction for partial volume effects in PET: principle and validation.
ROUSSET, O. G., Ma, Y., & Evans, A. C. (1998) · PubMed · Cited by 919
Self-citation
Psychological heterogeneity in AD/HD—a dual pathway model of behaviour and cognition
Sonuga-Barke, E. J. S. (2002) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00432-6 · Cited by 901
Dopamine transporter occupancies in the human brain induced by therapeutic doses of oral methylphenidate
Volkow, N. D., Wang, G.-J., Fowler, J. S., Gatley, S. J., Logan, J., Ding, Y.-S., Hitzemann, R., & Pappas, N. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.10.1325 · Cited by 885
Self-citation
Volumetric MRI analysis comparing subjects having attention-deficit hyperactivity disorder with normal controls
Filipek, P. A., Semrud-Clikeman, M., Steingard, R. J., Renshaw, P. F., Kennedy, D. N., & Biederman, J. (1997) · Neurology · doi:10.1212/wnl.48.3.589 · Cited by 732
Dopamine transporter density in patients with attention deficit hyperactivity disorder
Dougherty, D. D., Bonab, A. A., Spencer, T. J., Rauch, S. L., Madras, B. K., & Fischman, A. J. (1999) · The Lancet · doi:10.1016/s0140-6736(99)04030-1 · Cited by 684
Increased striatal dopamine transporter in adult patients with attention deficit hyperactivity disorder: effects of methylphenidate as measured by single photon emission computed tomography
Krause, K.-H., Dresel, S. H., Krause, J., Kung, H. F., & Tatsch, K. (2000) · Neuroscience Letters · doi:10.1016/s0304-3940(00)01040-5 · Cited by 521
Quantitative Brain Magnetic Resonance Imaging in Girls With Attention-Deficit/Hyperactivity Disorder
Castellanos, F. X., Giedd, J. N., Berquin, P. C., Walter, J. M., Sharp, W. S., Tran, T., Vaituzis, A. C., Blumenthal, J. D., Nelson, J. E., Bastain, T. M., et al. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.3.289 · Cited by 438
Catecholamines in Attention-Deficit Hyperactivity Disorder: Current Perspectives
Pliszka, S. R., McCracken, J. T., & Maas, J. W. (1996) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199603000-00006 · Cited by 436
Comparison of the monoamine transporters from human and mouse in their sensitivities to psychostimulant drugs
Han, D. D., & Gu, H. H. (2006) · BMC Pharmacology · doi:10.1186/1471-2210-6-6 · Cited by 419
The Dopamine Transporter and Attention-Deficit/Hyperactivity Disorder
Madras, B. K., Miller, G. M., & Fischman, A. J. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.10.011 · Cited by 393
Imaging endogenous dopamine competition with [11C]raclopride in the human brain
Volkow, N. D., Wang, G., Fowler, J. S., Logan, J., Schlyer, D., Hitzemann, R., Lieberman, J., Angrist, B., Pappas, N., MacGregor, R., et al. (1994) · Synapse · doi:10.1002/syn.890160402 · Cited by 379
Self-citation
Dopamine transporters and neuronal injury
Miller, G. W., Gainetdinov, R. R., Levey, A. I., & Caron, M. G. (1999) · Trends in Pharmacological Sciences · doi:10.1016/s0165-6147(99)01379-6 · Cited by 377
Dextroamphetamine: Cognitive and Behavioral Effects in Normal Prepubertal Boys
Rapoport, J. L., Buchsbaum, M. S., Zahn, T. P., Weingartner, H., Ludlow, C., & Mikkelsen, E. J. (1978) · Science · doi:10.1126/science.341313 · Cited by 373
Critical Involvement of Dopaminergic Neurotransmission in Impulsive Decision Making
van Gaalen, M. M., van Koten, R. C., Schoffelmeer, A. N. M., & Vanderschuren, L. J. M. J. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.06.005 · Cited by 338
Dysfunctional Attentional Networks in Children with Attention Deficit/Hyperactivity Disorder: Evidence from an Event-Related Functional Magnetic Resonance Imaging Study
Konrad, K., Neufang, S., Hanisch, C., Fink, G. R., & Herpertz-Dahlmann, B. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.08.013 · Cited by 335
Functional deficits in basal ganglia of children with attention-deficit/hyperactivity disorder shown with functional magnetic resonance imaging relaxometry
Teicher, M. H., Anderson, C. M., Polcari, A. M., Glod, C. A., Maas, L. C., & Renshaw, P. F. (2000) · Nature Medicine · doi:10.1038/74737 · Cited by 317
Chronic and acute regulation of Na+/Cl–-dependent neurotransmitter transporters: drugs, substrates, presynaptic receptors, and signaling systems
Zahniser, N. R., & Doolen, S. (2001) · Pharmacology & Therapeutics · doi:10.1016/s0163-7258(01)00158-9 · Cited by 311
The Nature and Heritability of Attention-Deficit/Hyperactivity Disorder
Faraone, S. V., & Doyle, A. E. (2001) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/s1056-4993(18)30059-2 · Cited by 304
Primate cingulostriatal projection: Limbic striatal versus sensorimotor striatal input
Kunishio, K., & Haber, S. N. (1994) · The Journal of Comparative Neurology · doi:10.1002/cne.903500302 · Cited by 290
Mapping cocaine binding sites in human and baboon brain in vivo
Fowler, J. S., Volkow, N. D., Wolf, A. P., Dewey, S. L., Schlyer, D. J., MacGregor, R. R., HITZEMANN, R. J., Logan, J., Bendriem, B., Gatley, S. J., et al. (1989) · Synapse · doi:10.1002/syn.890040412 · Cited by 289
Self-citation
Evidence That Methylphenidate Enhances the Saliency of a Mathematical Task by Increasing Dopamine in the Human Brain
Volkow, N. D., Wang, G.-J., Fowler, J. S., Telang, F., Maynard, L., Logan, J., Gatley, S. J., Pappas, N., Wong, C., Vaska, P., et al. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.7.1173 · Cited by 281
Self-citation
Attention deficit hyperactivity disorder: binding of [99mTc]TRODAT-1 to the dopamine transporter before and after methylphenidate treatment
Dresel, S., Krause, J., Krause, K.-H., LaFougere, C., Brinkbäumer, K., Kung, H. F., Hahn, K., & Tatsch, K. (2000) · European Journal of Nuclear Medicine · doi:10.1007/s002590000330 · Cited by 278
Antidepressants in panic disorder: clinical and preclinical mechanisms.
Conners, C. K. (1998) · PubMed · Cited by 277
Altered Neural Substrates of Cognitive Control in Childhood ADHD: Evidence From Functional Magnetic Resonance Imaging
Vaidya, C. J., Bunge, S. A., Dudukovic, N. M., Zalecki, C. A., Elliott, G. R., & Gabrieli, J. D. E. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.9.1605 · Cited by 269
Increased dopamine transporter availability associated with the 9-repeat allele of the SLC6A3 gene.
van Dyck, C. H., Malison, R. T., Jacobsen, L. K., Seibyl, J. P., Staley, J. K., Laruelle, M. A., Baldwin, R. M., Innis, R. B., & Gelernter, J. E. (2005) · PubMed · Cited by 257
High Midbrain [ 18 F]DOPA Accumulation in Children With Attention Deficit Hyperactivity Disorder
Ernst, M., Zametkin, A. J., Matochik, J. A., Pascualvaca, D., Jons, P. H., & Cohen, R. M. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.8.1209 · Cited by 256
Sex differences in [123I]β‐CIT SPECT measures of dopamine and serotonin transporter availability in healthy smokers and nonsmokers
Staley, J. K., Krishnan‐Sarin, S., Zoghbi, S. S., Tamagnan, G. D., Fujita, M., Seibyl, J. P., Maciejewski, P. K., O’Malley, S. S., & Innis, R. B. (2001) · Synapse · doi:10.1002/syn.1084 · Cited by 247
Reduced midbrain dopamine transporter binding in male adolescents with attention-deficit/hyperactivity disorder: Association between striatal dopamine markers and motor hyperactivity
Jucaite, A., Fernell, E., Halldin, C., Forssberg, H., & Farde, L. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2004.11.009 · Cited by 236
PET Study Examining Pharmacokinetics, Detection and Likeability, and Dopamine Transporter Receptor Occupancy of Short- and Long-Acting Oral Methylphenidate
Spencer, T. J., Biederman, J., E. Ciccone, P., Madras, B. K., Dougherty, D. D., Bonab, A. A., Livni, E., Parasrampuria, D. A., & Fischman, A. J. (2006) · American Journal of Psychiatry · doi:10.1176/appi.ajp.163.3.387 · Cited by 206
Attention-deficit/hyperactivity disorder (ADHD) behaviour explained by dysfunctioning reinforcement and extinction processes
Johansen, E. B., Aase, H., Meyer, A., & Sagvolden, T. (2002) · Behavioural Brain Research · doi:10.1016/s0166-4328(01)00434-x · Cited by 195
Dopamine transporter density in the basal ganglia assessed with [123I]IPT SPET in children with attention deficit hyperactivity disorder
Cheon, K.-A. A., Ryu, Y. H., Kim, Y.-K., Namkoong, K., Kim, C., & Lee, J. E. (2003) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-002-1047-3 · Cited by 189
In Vivo Neuroreceptor Imaging in Attention-Deficit/Hyperactivity Disorder: A Focus on The Dopamine Transporter
Spencer, T. J., Biederman, J., Madras, B. K., Faraone, S. V., Dougherty, D. D., Bonab, A. A., & Fischman, A. J. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.03.036 · Cited by 185
Effects of Blood Flow on [ 11 C]Raclopride Binding in the Brain: Model Simulations and Kinetic Analysis of PET Data
Logan, J., Volkow, N. D., Fowler, J. S., Wang, G., Dewey, S. L., MacGregor, R. R., Schlyer, D. J., Gatley, S. J., Pappas, N. R., King, P. T., et al. (1994) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1994.132 · Cited by 167
Self-citation
The homozygosity for 10-repeat allele at dopamine transporter gene and dopamine transporter density in Korean children with attention deficit hyperactivity disorder: relating to treatment response to methylphenidate
Cheon, K.-A. A., Ryu, Y. H., Kim, J.-W., & Cho, D.-Y. (2004) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2004.06.004 · Cited by 162
Elevated Striatal Dopamine Transporters During Acute Cocaine Abstinence as Measured by [123I]β-CIT SPECT
Malison, R. T., Best, S. E., van Dyck, C. H., McCance, E. F., Wallace, E. A., Laruelle, M. A., Baldwin, R. M., Seibyl, J. P., Price, L. H., Kosten, T. R., et al. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.6.832 · Cited by 156
Heterogeneous subregional binding patterns of 3H-WIN 35,428 and 3H-GBR 12,935 are differentially regulated by chronic cocaine self- administration
Wilson, J., Nobrega, J., Carroll, M., Niznik, H. B., Shannak, K. S., Lac, S., Pristupa, Z. B., Dixon, L., & Kish, S. J. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-05-02966.1994 · Cited by 143
Unaltered Dopamine Transporter Availability in Adult Attention Deficit Hyperactivity Disorder
van Dyck, C. H., Quinlan, D. M., Cretella, L. M., Staley, J. K., Malison, R. T., Baldwin, R. M., Seibyl, J. P., & Innis, R. B. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.2.309 · Cited by 139
Clinical foundations of hyperactivity research
Taylor, E. A. (1998) · Behavioural Brain Research · doi:10.1016/s0166-4328(97)00165-4 · Cited by 134
The dopamine transporter proteome
Torres, G. E. (2006) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2006.03719.x · Cited by 126
Striatal Dopaminergic Abnormalities in Human Cocaine Users
Little, K. Y., Zhang, L., Desmond, T., Frey, K. A., Dalack, G. W., & Cassin, B. J. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.2.238 · Cited by 116
Putamen Lesions and the Development of Attention-Deficit/Hyperactivity Symptomatology
Max, J. E., Fox, P. T., Lancaster, J. L., Kochunov, P. V., Mathews, K. D., Manes, F. F., Robertson, B., Arndt, S. V., Robin, D. A., & Lansing, A. E. (2002) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200205000-00014 · Cited by 114
Repeated methylphenidate treatment in adolescent rats alters gene regulation in the striatum
Brandon, C. L., & Steiner, H. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02892.x · Cited by 105
Basal ganglia lesions and the theory of fronto-subcortical loops: neuropsychological findings in two patients with left caudate lesions
Benke, T., Delazer, M., Bartha, L., & Auer, A. (2003) · Neurocase · doi:10.1076/neur.9.1.70.14374 · Cited by 102
Hypothalamic-pituitary-adrenal axis function in children with attention-deficit hyperactivity disorder
Kaneko, M., Hoshino, Y., Hashimoto, S., Okano, T., & Kumashiro, H. (1993) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01066418 · Cited by 96
ADHD: increased dopamine receptor availability linked to attention deficit and low neonatal cerebral blood flow
Lou, H. C., Rosa‐Neto, P., Pryds, O. A., Karrebæk, H., Lunding, J. M. C., Cumming, P. D., & GJEDDE, A. H. (2004) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162204000313 · Cited by 90
Stimulant-like action of nicotine on striatal dopamine transporter in the brain of adults with attention deficit hyperactivity disorder
Krause, K.-H., Dresel, S. H., Krause, J., Kung, H. F., Tatsch, K., & Ackenheil, M. (2002) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145702002821 · Cited by 88
Brain Dopamine Transporter Messenger RNA and Binding Sites in Cocaine Users
Little, K. Y., McLaughlin, D. P., Zhang, L., McFinton, P. R., Dalack, G. W., Cook, E. H., Cassin, B. J., & Watson, S. J. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.9.793 · Cited by 76
Impact of ε and θ subunits on pharmacological properties of α3β1 GABAA receptors expressed in Xenopus oocytes
Ranna, M., Sinkkonen, S. T., Möykkynen, T. P., Uusi‐Oukari, M., & Korpi, E. R. (2006) · BMC Pharmacology · doi:10.1186/1471-2210-6-1 · Cited by 75
Is increased D2 receptor availability associated with response to stimulant medication in ADHD
Ilgin, N., Şenol, S., Gücüyener, K., Gökçora, N., Atavci, S., & Şener, Ş. (2001) · Developmental Medicine & Child Neurology · doi:10.1017/s0012162201001384 · Cited by 75
Involvement of Norepinephrine in the Control of Activity and Attentive Processes in Animal Models of Attention Deficit Hyperactivity Disorder
Viggiano, D., Ruocco, L. A., Arcieri, S., & Sadile, A. G. (2004) · Neural Plasticity · doi:10.1155/np.2004.133 · Cited by 71
Chronic cocaine administration is associated with behavioral sensitization and time-dependent changes in striatal dopamine transporter binding.
Koff, J. M., Shuster, L., & Miller, L. G. (1994) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)38476-4 · Cited by 65
Localization of GTP cyclohydrolase in monoaminergic but not nitric oxide-producing cells
Hwang, O., Baker, H. A., Gross, S. S., & JOH, T. H. (1998) · Synapse · doi:10.1002/(sici)1098-2396(199802)28:2 · Cited by 62
Self-citation
Striatal dopamine transporter density in drug naive patients with attention-deficit/hyperactivity disorder
Larisch, R., Sitte, W., Antke, C., Nikolaus, S., Franz, M., Tress, W., & M??ller, H.-W. (2006) · Nuclear Medicine Communications · doi:10.1097/00006231-200603000-00010 · Cited by 58
Methylphenidate‐Evoked Potentiation of Extracellular Dopamine in the Brain of Adolescents with Premature Birth: Correlation with Attentional Deficit
NETO, P. R., LOU, H., CUMMING, P., PRYDS, O., & GJEDDE, A. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb04184.x · Cited by 54
Carbon-11-cocaine binding compared at subpharmacological and pharmacological doses: a PET study.
Volkow, N. D., Fowler, J. S., Logan, J., Gatley, S. J., Dewey, S. L., MacGregor, R. R., Schlyer, D. J., Pappas, N. R., King, P., & Wang, G. (1995) · PubMed · Cited by 47
Self-citation
Sensitivity of striatal [11C]cocaine binding to decreases in synaptic dopamine
Gatley, S. J., Volkow, N. D., Fowler, J. S., Dewey, S. L., & Logan, J. (1995) · Synapse · doi:10.1002/syn.890200207 · Cited by 33
Self-citation

Flagged first, then by citations

6 of the 73 references couldn’t be matched to a known paper.

Research works printed but not linked: 3

Conners, 1998, Rating scales in attention-deficit/hyperactivity disorder: use in assessment and treatment monitoring, J. Clin. Psychiatry, 59, 24
Hesse, 2006, The striatal dopamine transporter availability is reduced in adults with attention-deficit/hyperactivity disorder, J. Nucl. Med., 47, 142
National Institutes of Health (NIH), 2000, Consensus Development Conference Statement: diagnosis and treatment of attention deficit/hyperactivity disorder (ADHD), J. Am. Acad. Child Adolesc. Psych., 39, 192

Sorted by citations

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Self-citation
Insights into the neural basis of response inhibition from cognitive and clinical neuroscience
Chambers, C. D., Garavan, H., & Bellgrove, M. A. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.08.016 · Cited by 938
European consensus statement on diagnosis and treatment of adult ADHD: The European Network Adult ADHD
Kooij, S. J., Bejerot, S., Blackwell, A., Caci, H., Casas-Brugué, M., Carpentier, P. J., Edvinsson, D., Fayyad, J., Foeken, K., Fitzgerald, M., et al. (2010) · BMC Psychiatry · doi:10.1186/1471-244x-10-67 · Cited by 928
“Fronto-striatal dysfunction and increased dopamine transporter density in the striatum have both been reported [83-86] although the finding of increased dopamine transporter density remains a controversial finding, perhaps secondary to drug treatments for ADHD [87,88].”
Evaluating Dopamine Reward Pathway in ADHD: Clinical Implications
Volkow, N. D., Wang, G.-J., Kollins, S. H., Wigal, T. L., Newcorn, J. H., Telang, F., Fowler, J. S., Zhu, W., Logan, J., Ma, Y., et al. (2009) · JAMA · doi:10.1001/jama.2009.1308 · Cited by 728
Self-citation
Updated European Consensus Statement on diagnosis and treatment of adult ADHD
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See all 249

Authors: Volkow, N. D., Wang, G.-J., Newcorn, J., Fowler, J. S., Telang, F., Solanto, M. V., Logan, J., Wong, C., Ma, Y., Swanson, J. M., Schulz, K., & Pradhan, K.
Affiliations: National Institute on Drug Abuse (US)
Brookhaven National Laboratory (US)
Mount Sinai Hospital (US)
National Institute on Alcohol Abuse and Alcoholism (US)
University of California, Irvine (US)
State University of New York (US)
Corresponding author: Volkow, Nora D.
ORCID: Volkow, Nora D.
Wang, Gene-Jack
Newcorn, Jeffrey
Solanto, Mary V.
Logan, Jean
Wong, Christopher
Swanson, James M.
Schulz, Kurt
Pradhan, Kith
Venue: NeuroImage
Publisher: Elsevier BV
Published: 2007-02
Volume: 34
Issue: 3
Pages: 1182-1190
ISSN: 1053-8119 (ISSN-L)
DOI: 10.1016/j.neuroimage.2006.10.014
OpenAlex: W2082738856
Cited by: 249
References: 73
Citations by year: 2026: 5 · 2025: 7 · 2024: 9 · 2023: 7 · 2022: 9 · 2021: 7 · 2020: 11 · 2019: 4 · 2018: 12 · 2017: 10 · 2016: 11 · 2015: 13 · 2014: 24 · 2013: 14 · 2012: 22
FWCI: 11.29
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: NeuroImage (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health
National Institute of Mental Health (MH66961-02, R01MH066961)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords: attention deficit hyperactivity disorder, dopamine transporter, caudate nucleus, nucleus accumbens, putamen, inattention, adult ADHD, neurobiology of ADHD, noradrenergic neurotransmission
MeSH terms: Adult, Central Nervous System Stimulants, Attention Deficit Disorder with Hyperactivity, Brain, Carbon Radioisotopes, Cocaine, Female, Humans, Male, Tissue Distribution, Radiopharmaceuticals, Positron-Emission Tomography, Dopamine Plasma Membrane Transport Proteins

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Brain dopamine transporter levels in treatment and drug naive adults with ADHD

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