Cited by 110Neurotransmitter Receptor Influence on BehaviorNicotinic Acetylcholine Receptors StudySmoking Behavior and Cessation

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Neuroadaptive changes in the mesoaccumbens dopamine system after chronic nicotine self-administration: A microdialysis study

Rahman, S., Zhang, J., Engleman, E.A., Corrigall, W.A.·2004·Neuroscience

DOI 10.1016/j.neuroscience.2004.08.010

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Abstract

There is little evidence to date to indicate if mesoaccumbens dopamine function at the neurochemical level is altered during early abstinence from chronic i.v. nicotine self-administration. Thus, a quantitative microdialysis (no-net-flux) approach was used to measure basal extracellular concentrations and extraction fractions of dopamine in the nucleus accumbens (ACB) of rats that self-administered nicotine i.v. for 25 days, as well as in rats serving as yoked comparison groups (yoked nicotine and yoked saline). After 24-48 h of the final self-administration session, there was a significant reduction in basal extracellular dopamine levels in the ACB of the self-administration group compared with the yoked saline group (1.35+/-0.15 nM versus 3.70+/-0.28 nM). The basal extracellular dopamine levels in the yoked nicotine group (1.46+/-0.20 nM) were not significantly different compared with the nicotine self-administration group. The in vivo extraction fraction of dopamine, an indirect measure of dopamine uptake, was significantly increased in the nicotine self-administration (86%) and yoked nicotine (91%) groups compared with the yoked saline group (77%). In addition, a marked reduction in the elevation of extracellular dopamine levels in the ACB occurred after a nicotine challenge as measured by conventional microdialysis in the self-administration (112% of basal) and yoked nicotine (121% of basal) groups as compared with a yoked saline (154% of basal) group. The reduced basal ACB dopamine levels in the nicotine groups during early abstinence appears to be due to increased clearance, suggesting increased dopamine uptake is occurring as a result of the chronic nicotine treatment. The reduced elevation of extracellular dopamine levels in the ACB upon nicotine challenge suggests a functional desensitization or downregulation phenomenon involving acetylcholine receptors (nicotinic nAChRs). Overall, these results provide clear evidence for a neuroadaptive change that alters dopamine transmission in the ACB during abstinence from chronic i.v. nicotine exposure.

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The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585
Drug Addiction, Dysregulation of Reward, and Allostasis
Koob, G. (2001) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00195-0 · Cited by 2,953
Specificity in the projection patterns of accumbal core and shell in the rat
Heimer, L., Zahm, D. S., Churchill, L., Kalivas, P. W., & Wohltmann, C. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90202-y · Cited by 1,219
Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs.
Pontieri, F. E., Tanda, G., Orzi, F., & Chiara, G. D. (1996) · Nature · doi:10.1038/382255a0 · Cited by 1,073
The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine
Corrigall, W. A., Franklin, K. B. J., Coen, K. M., & Clarke, P. B. S. (1992) · Psychopharmacology · doi:10.1007/bf02245149 · Cited by 829
Self-citation
Nicotine activates and desensitizes midbrain dopamine neurons
Pidoplichko, V. I., DeBiasi, M., Williams, J. T., & Dani, J. A. (1997) · Nature · doi:10.1038/37120 · Cited by 769
Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area
Corrigall, W. A., Coen, K. M., & Adamson, K. L. (1994) · Brain Research · doi:10.1016/0006-8993(94)90401-4 · Cited by 740
Role of dopamine in the behavioural actions of nicotine related to addiction
Chiara, G. D. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(00)00122-9 · Cited by 698
Dramatic decreases in brain reward function during nicotine withdrawal
Epping-Jordan, M. P., Watkins, S. S., Koob, G. F., & Markou, A. (1998) · Nature · doi:10.1038/30001 · Cited by 674
Mortality from smoking worldwide
Peto, R., Lopez, A. D., Boreham, J., Thun, M., Heath, C., & Doll, R. (1996) · British Medical Bulletin · doi:10.1093/oxfordjournals.bmb.a011519 · Cited by 638

Show all 64 references

Research works printed but not linked: 3

Balfour, 2003, The psychopharmacology of tobacco dependence, J Clin Psychiatry Monogr, 18, 12
Lonnroth, 1987, A microdialysis method allowing characterization of intracellular water space in humans, Am J Physiol, 253, E228
Marks, 1985, Time course of the effects of chronic nicotine infusion on drug responses and brain receptors, J Pharmacol Ther, 235, 619

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Authors: Rahman, S., Zhang, J., Engleman, E. A., & Corrigall, W. A.
Affiliations: Centre for Addiction and Mental Health (CA)
Indiana University Indianapolis (US)
Corresponding author: Rahman, S.
ORCID: Rahman, S.
Venue: Neuroscience
Publisher: Elsevier BV
Published: 2004-01
Volume: 129
Issue: 2
Pages: 415-424
ISSN: 0306-4522 (ISSN-L)
DOI: 10.1016/j.neuroscience.2004.08.010
OpenAlex: W2033657283
Cited by: 110
References: 64
Citations by year: 2025: 1 · 2024: 3 · 2023: 3 · 2022: 1 · 2021: 4 · 2020: 2 · 2018: 3 · 2017: 1 · 2016: 5 · 2015: 6 · 2014: 11 · 2013: 5 · 2012: 10
FWCI: 2.11
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neuroscience (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5r01da009577-06)
National Institute on Drug Abuse (DA 09577)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Nicotinic Acetylcholine Receptors Study
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
Keywords: nicotine self-administration, nicotine abstinence, nucleus accumbens, extracellular dopamine, dopamine uptake, extraction fraction, acetylcholine receptor, nicotinic receptor desensitization, neural adaptation, chronic nicotine exposure
MeSH terms: Adaptation, Physiological, Animals, Chromatography, High Pressure Liquid, Conditioning, Operant, Dopamine, Extracellular Space, Infusions, Intravenous, Male, Synaptic Transmission, Nicotine, Nucleus Accumbens, Self Administration, Substance Withdrawal Syndrome, Microdialysis, Nicotinic Agonists, Rats, Long-Evans, Rats

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Neuroadaptive changes in the mesoaccumbens dopamine system after chronic nicotine self-administration: A microdialysis study

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