Dietary nitrate-good or bad?
Abstract
There has now been a great deal written about inorganic nitrate in both the popular press and in scientific journals. Papers in the 1970s warned us that inorganic nitrate could theoretically be metabolised in the human body to N-nitroso compounds, many of which are undoubtedly carcinogenic. More recently there is evidence that nitrate can undergo metabolic conversion to nitrite and nitric oxide and perform a useful protective function to prevent infection, protect our stomach, improve exercise performance and prevent vascular disease.
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Recent studies have found no link between dietary nitrate and cancer.
“Consistent with this, recent studies have found no link between dietary nitrate and cancer [143,144].”
From NO-Rich Diet for Lifestyle-Related Diseases (2015) · cites this paper as [143]
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- Authors
- Gilchrist, M., Winyard, P. G., & Benjamin, N.
- Affiliations
- University of Exeter (GB)
- Corresponding author
- Gilchrist, Mark
- Venue
- Nitric Oxide
- Publisher
- Elsevier BV
- Published
- 2010-02
- Volume
- 22
- Issue
- 2
- Pages
- 104-109
- ISSN
- 1089-8603 (ISSN-L)
- OpenAlex
- W1969638214
- Cited by
- 157
- References
- 89
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 3 · 2023: 9 · 2022: 22 · 2021: 4 · 2020: 7 · 2019: 9 · 2018: 3 · 2017: 19 · 2016: 10 · 2015: 12 · 2014: 16 · 2013: 10 · 2012: 6
- FWCI
- 0.99
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nitric Oxide (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Nitric Oxide and Endothelin Effects
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Keywords
- dietary nitrate, inorganic nitrate, nitrite, N-nitroso compounds, carcinogenicity, infection control, gastroprotection, exercise performance, vascular disease prevention
- MeSH terms
- Animals, Diet, Humans, Nitrates
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