The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Astaxanthin: A mechanistic review on its biological activities and health benefits
Abstract
ABSTRACT Astaxanthin (AST) is a potent lipid‐soluble keto‐carotenoid with auspicious effects on human health. It protects organisms against a wide range of diseases with excellent safety and tolerability. Various imperative biological activities in vitro and in vivo models have been suggested for AST. This review article is focused on the therapeutic potentials, biological activities and benefical health effects of AST. The pharmacological mechanisms of action of AST in the treatment and prevention of the peripheral and central nervous system diseases was also reviewed to provide new insights to researchers. Finally, we suggested a novel hypothesis for the mechanism of action of AST in neuropathic pain following spinal cord injury.
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Cites
Apoptosis: A Review of Programmed Cell Death
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EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revision
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Haematococcus astaxanthin: applications for human health and nutrition
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Astaxanthin: a review of its chemistry and applications
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Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae
Yuan, J., Peng, J., Yin, K., & Wang, J. (2011) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201000414 · Cited by 649
Cosmetic benefits of astaxanthin on humans subjects.
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Trends in use, pharmacology, and clinical applications of emerging herbal nutraceuticals
Williamson, E. M., Liu, X., & Izzo, A. A. (2020) · British Journal of Pharmacology · doi:10.1111/bph.14943 · Cited by 304
Chang, M. X., & Xiong, F. (2020) · Molecules · doi:10.3390/molecules25225342 · Cited by 268
Microalgae Encapsulation Systems for Food, Pharmaceutical and Cosmetics Applications
Vieira, M. V., Pastrana, L. M., & Fuciños, P. (2020) · Marine Drugs · doi:10.3390/md18120644 · Cited by 205
Rizvi, S. A. A., Einstein, G. P., Tulp, O. L., Sainvil, F., & Branly, R. (2022) · Biomolecules · doi:10.3390/biom12101442 · Cited by 181
“It reacts vigorously with other free radicals, depending on the polyene system length and the terminal rings [120].”
BackgroundMartínez-Álvarez, Ó., Calvo, M. M., & Gómez-Estaca, J. (2020) · Marine Drugs · doi:10.3390/md18080406 · Cited by 148
Metadata
- Authors
- Fakhri, S., Abbaszadeh, F., Dargahi, L., & Jorjani, M.
- Venue
- Pharmacological Research
- Publisher
- Elsevier BV
- Published
- 2018-10
- Volume
- 136
- Pages
- 1-20
- ISSN
- 1043-6618 (ISSN-L)
- OpenAlex
- W2885341903
- Cited by
- 461
- References
- 19
- FWCI
- 21.92
- Type
- journal article
- Language
- en
- Open access
- closed
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- Fakhri, S., Abbaszadeh, F., Dargahi, L., & Jorjani, M. (2018). Astaxanthin: A mechanistic review on its biological activities and health benefits. Pharmacological Research. https://doi.org/10.1016/j.phrs.2018.08.012
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
