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Cited by 181Smoking Behavior and CessationSchizophrenia research and treatmentCardiovascular Health and Risk Factors

Healthy lifestyle habits and 10-year cardiovascular risk in schizophrenia spectrum disorders: An analysis of the impact of smoking tobacco in the CLAMORS schizophrenia cohort

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Bobes, Julio, Arango, Celso, Garcia-Garcia, Margarida, Rejas, Javier·2010·Schizophrenia Research
DOI 10.1016/j.schres.2010.02.1030
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Abstract

Aim We analysed the impact of tobacco smoking over several healthy lifestyle habits along with the impact on 10-years cardiovascular event (CVE) risk in the CLAMORS schizophrenia cohort. Methods This analysis was performed within the scope of the CLAMORS study which included consecutive outpatients meeting DSM-IV criteria for schizophrenia spectrum disorder. Beside smoking history, data on usual healthy lifestyle habits included current exercise, saturated fat sparing diet, low-caloric diet, and daily dietary fibre, salt, caffeine and alcohol consumption were recorded. The 10-year CVE risk was calculated with Framingham function. Results 1704 patients (61.1% male), 18 to 74 years were examined. Prevalence of smoking was 54.54% (95% CI: 52.16%-56.90%) significantly higher than in age and sex matched general population subjects, 31.51% (31.49%-31.52%); OR=2.61 (2.37-2.87, p<0.0001). After controlling by confounders smokers showed a 10-year CVE risk excess versus non-smokers of 2.63 (2.16-3.09), p<0.001. Smoking cessation would reduce the likely of high/very high 10-year CVE risk (above 10%) by near 90% [OR=0.10 (0.06-0.18), p<0.0001]. Also, smokers were more likely to consume alcohol daily [4.13 (3.07-5.54), p<0.0001] and caffeine [3.39 (2.72-4.23), p<0.0001] than non-smoker patients with schizophrenia, and less likely to avoid daily consumption of salt [0.58 (0.43-0.78), p<0.0001], saturated fat [0.71 (0.56-0.91), p=0.006], high fibre diet [0.67 (0.53-0.84), p=0.001], or to follow a low-caloric diet [0.63 (0.48-0.81), p<0.0001]. Smokers also were less likely to do exercise habitually [0.62 (0.48-0.82, p=0.001]. Conclusion Compared with the general population, patients with schizophrenia showed significant higher prevalence of smoking. Smokers who stop smoking would benefit by a near 90% reduction in the likely of 10-year cardiovascular event risk above 10%.

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  • A large study from Spain found that 55% of nearly 2,000 outpatients with schizophrenia were smokers.

    “A large study from Spain found that 55% of nearly 2,000 outpatients with schizophrenia were smokers (Bobes et al. 2010).”

    From Excess early mortality in schizophrenia. (2014) · cites this paper as Bobes et al. 2010

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Authors
Bobes, J., Arango, C., Garcia-Garcia, M., & Rejas, J.
Affiliations
  • Universidad de Oviedo (ES)
  • Hospital General Universitario Gregorio Marañón (ES)
  • Pfizer (Spain) (ES)
ORCID
Venue
Schizophrenia Research
Publisher
Elsevier BV
Published
2010-06
Volume
119
Issue
1-3
Pages
101-109
ISSN
0920-9964 (ISSN-L)
DOI
10.1016/j.schres.2010.02.1030
OpenAlex
W2152889938
Cited by
181
References
40
Citations by year
2026: 2 · 2025: 2 · 2024: 5 · 2023: 7 · 2022: 6 · 2021: 15 · 2020: 6 · 2019: 8 · 2018: 20 · 2017: 8 · 2016: 12 · 2015: 9 · 2014: 12 · 2013: 20 · 2012: 19
FWCI
14.93
Type
journal article
Language
en
Open access
Licence
Locations
  • Schizophrenia Research (publishedVersion)
  • PubMed (publishedVersion)
  • Consultation of the Doctoral Thesis Database (TESEO) (Ministerio de Educación, Cultura y Deporte) (submittedVersion, cc-by-nc-nd)
Topics
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
Keywords
schizophrenia spectrum disorders, smoking
MeSH terms
Cardiac Rehabilitation, Adolescent, Adult, Aged, Cardiovascular Diseases, Cross-Sectional Studies, Feeding Behavior, Female, Health Status Indicators, Health Surveys, Humans, Life Style, Male, Middle Aged, Psychotic Disorders, Risk, Schizophrenia, Schizophrenic Psychology, Smoking, Spain, Cohort Studies, Comorbidity, Case-Control Studies, Smoking Cessation, Risk Assessment, Metabolic Syndrome, Young Adult

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