Making RISC

Origins and Mechanisms of miRNAs and siRNAs

Carthew, R. W., & Sontheimer, E. J. (2009) · Cell · doi:10.1016/j.cell.2009.01.035 · Cited by 5,023 · see citing works

Prediction of Mammalian MicroRNA Targets

Lewis, B. P., Shih, I.-H., Jones-Rhoades, M. W., Bartel, D. P., & Burge, C. B. (2003) · Cell · doi:10.1016/s0092-8674(03)01018-3 · Cited by 4,333 · see citing works

MicroRNA Targeting Specificity in Mammals: Determinants beyond Seed Pairing

Grimson, A., Farh, K. K.-H., Johnston, W. K., Garrett-Engele, P., Lim, L. P., & Bartel, D. P. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.06.017 · Cited by 3,766 · see citing works

RNA interference is mediated by 21- and 22-nucleotide RNAsPreprint

Elbashir, S. M., Lendeckel, W., & Tuschl, T. (2001) · Genes & Development · doi:10.1101/gad.862301 · Cited by 3,308 · see citing works

Biogenesis of small RNAs in animals

Kim, V. N., Han, J., & Siomi, M. C. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2632 · Cited by 3,181 · see citing works

Functional siRNAs and miRNAs exhibit strand bias

Khvorova, A., Reynolds, A., & Jayasena, S. D. (2003) · Cell · doi:10.1016/s0092-8674(03)00801-8 · Cited by 2,645 · see citing works

Principles of MicroRNA–Target Recognition

Brennecke, J., Stark, A., Russell, R. B., & Cohen, S. M. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030085 · Cited by 2,384 · see citing works

Argonaute2 is the catalytic engine of mammalian RNAi

Liu, J., Carmell, M. A., Rivas, F. V., Marsden, C. G., Thomson, J. M., Song, J.-J., Hammond, S. M., Joshua-Tor, L., & Hannon, G. J. (2004) · Science · doi:10.1126/science.1102513 · Cited by 2,353 · see citing works

Asymmetry in the Assembly of the RNAi Enzyme Complex

Schwarz, D. S., Hutvágner, G., Du, T., Xu, Z., Aronin, N., & Zamore, P. D. (2003) · Cell · doi:10.1016/s0092-8674(03)00759-1 · Cited by 2,323 · see citing works

Small silencing RNAs: an expanding universe

Ghildiyal, M., & Zamore, P. D. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2504 · Cited by 2,314 · see citing works

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

Meister, G., Landthaler, M., Patkaniowska, A., Dorsett, Y., Teng, G., & Tuschl, T. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.07.007 · Cited by 1,718 · see citing works

Specificity of microRNA target selection in translational repressionPreprint

Doench, J. G., & Sharp, P. A. (2004) · Genes & Development · doi:10.1101/gad.1184404 · Cited by 1,642 · see citing works

Molecular Basis for the Recognition of Primary microRNAs by the Drosha-DGCR8 Complex

Han, J., Lee, Y., Yeom, K., Nam, J., Heo, I., Rhee, J., Sohn, S. Y., Cho, Y., Zhang, B.-T., & Kim, V. N. (2006) · Cell · doi:10.1016/j.cell.2006.03.043 · Cited by 1,552 · see citing works

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi.

Martı̂nez, J., Patkaniowska, A., Urlaub, H., Lührmann, R., & Tuschl, T. (2002) · Cell · doi:10.1016/s0092-8674(02)00908-x · Cited by 1,550 · see citing works

Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity

Song, J., Smith, S. K., Hannon, G. J., & Joshua‐Tor, L. (2004) · Science · doi:10.1126/science.1102514 · Cited by 1,465 · see citing works

A Distinct Small RNA Pathway Silences Selfish Genetic Elements in the Germline

Vagin, V. V., Sigova, A. A., Li, C., Seitz, H., Gvozdev, V. A., & Zamore, P. D. (2006) · Science · doi:10.1126/science.1129333 · Cited by 1,342 · see citing works

Sorting of Small RNAs into Arabidopsis Argonaute Complexes Is Directed by the 5′ Terminal Nucleotide

Mi, S., Cai, T., Hu, Y., Chen, Y., Hodges, E. C., Ni, F., Wu, L., Li, S., Zhou, H., Long, C., et al. (2008) · Cell · doi:10.1016/j.cell.2008.02.034 · Cited by 1,311 · see citing works

Distinct Roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA Silencing Pathways

Lee, Y. S., Nakahara, K., Pham, J. W., Kim, K., He, Z., Sontheimer, E. J., & Carthew, R. W. (2004) · Cell · doi:10.1016/s0092-8674(04)00261-2 · Cited by 1,287 · see citing works

Human RISC Couples MicroRNA Biogenesis and Posttranscriptional Gene Silencing

Gregory, R. I., Chendrimada, T. P., Cooch, N., & Shiekhattar, R. (2005) · Cell · doi:10.1016/j.cell.2005.10.022 · Cited by 1,268 · see citing works

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencingPreprint

Kanellopoulou, C., Muljo, S. A., Kung, A. L., Ganesan, S., Drapkin, R., Jenuwein, T., Livingston, D. M., & Rajewsky, K. (2005) · Genes & Development · doi:10.1101/gad.1248505 · Cited by 1,256 · see citing works

ATP Requirements and Small Interfering RNA Structure in the RNA Interference Pathway

Nykänen, A., Haley, B., & Zamore, P. D. (2001) · Cell · doi:10.1016/s0092-8674(01)00547-5 · Cited by 1,017 · see citing works

Passenger-Strand Cleavage Facilitates Assembly of siRNA into Ago2-Containing RNAi Enzyme Complexes

Matranga, C., Tomari, Y., Shin, C., Bartel, D. P., & Zamore, P. D. (2005) · Cell · doi:10.1016/j.cell.2005.08.044 · Cited by 969 · see citing works

Perspective: machines for RNAiPreprint

Tomari, Y., & Zamore, P. D. (2005) · Genes & Development · doi:10.1101/gad.1284105 · Cited by 950 · see citing works

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathwaysPreprint

岡村, 勝., Ishizuka, A., Siomi, H., & Siomi, M. C. (2004) · Genes & Development · doi:10.1101/gad.1210204 · Cited by 833 · see citing works

Argonaute2 Cleaves the Anti-Guide Strand of siRNA during RISC Activation

Rand, T., Petersen, S., Du, F., & Wang, X. (2005) · Cell · doi:10.1016/j.cell.2005.10.020 · Cited by 784 · see citing works

Specificity of ARGONAUTE7-miR390 Interaction and Dual Functionality in TAS3 Trans-Acting siRNA Formation

Montgomery, T. A., Howell, M. D., Cuperus, J. T., Li, D., Hansen, J. E., Alexander, A. L., Chapman, E. J., Fahlgren, N., Allen, E. M., & Carrington, J. C. (2008) · Cell · doi:10.1016/j.cell.2008.02.033 · Cited by 775 · see citing works

Purified Argonaute2 and an siRNA form recombinant human RISC

Rivas, F. V., Tolia, N. H., Song, J., Aragon, J. P., Liu, J., Hannon, G. J., & Joshua‐Tor, L. (2005) · Nature Structural & Molecular Biology · doi:10.1038/nsmb918 · Cited by 760 · see citing works

R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway

Liu, Q., Rand, T., Kalidas, S., et al. (2003) · Science · doi:10.1126/science.1088710 · Cited by 705 · see citing works

Dual Role for Argonautes in MicroRNA Processing and Posttranscriptional Regulation of MicroRNA Expression

Diederichs, S., & Haber, D. A. (2007) · Cell · doi:10.1016/j.cell.2007.10.032 · Cited by 687 · see citing works

Characterization of Dicer-deficient murine embryonic stem cells

Murchison, E. P., Partridge, J. F., Tam, O. H., Cheloufi, S., & Hannon, G. J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0505479102 · Cited by 684 · see citing works

MicroRNA control of PHABULOSA in leaf development: importance of pairing to the microRNA 5′ region

Mallory, A. C., Reinhart, B. J., Jones-Rhoades, M. W., Tang, G., Zamore, P. D., Barton, M. K., & Bartel, D. P. (2004) · The EMBO Journal · doi:10.1038/sj.emboj.7600340 · Cited by 681 · see citing works

Structural basis for 5′-end-specific recognition of guide RNA by the A. fulgidus Piwi protein

Ma, J., Yuan, Y. A., Meister, G., Pei, Y., Tuschl, T., & Patel, D. J. (2005) · Nature · doi:10.1038/nature03514 · Cited by 649 · see citing works

Distinct Populations of Primary and Secondary Effectors During RNAi in C. elegans

Pak, J., & Fire, A. Z. (2006) · Science · doi:10.1126/science.1132839 · Cited by 631 · see citing works

A Protein Sensor for siRNA Asymmetry

Tomari, Y., Matranga, C. B., Haley, B., Martinez, N. J., & Zamore, P. D. (2004) · Science · doi:10.1126/science.1102755 · Cited by 601 · see citing works

Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex

Wang, Y., Juranek, S., Li, H., Sheng, G., Tuschl, T., & Patel, D. J. (2008) · Nature · doi:10.1038/nature07666 · Cited by 577 · see citing works

Normal microRNA Maturation and Germ-Line Stem Cell Maintenance Requires Loquacious, a Double-Stranded RNA-Binding Domain Protein

Förstemann, K., Tomari, Y., Du, T., Vagin, V. V., Denli, A. M., Bratu, D. P., Klattenhoff, C., Theurkauf, W. E., & Zamore, P. D. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030236 · Cited by 545 · see citing works

Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes

Wang, Y., Juranek, S., Li, H., Sheng, G., Wardle, G. S., Tuschl, T., & Patel, D. J. (2009) · Nature · doi:10.1038/nature08434 · Cited by 542 · see citing works

Structure of the guide-strand-containing argonaute silencing complex

Wang, Y., Sheng, G., Juranek, S., Tuschl, T., & Patel, D. J. (2008) · Nature · doi:10.1038/nature07315 · Cited by 531 · see citing works

Structural insights into mRNA recognition from a PIWI domain–siRNA guide complex

Parker, J. S., Roe, S. M., & Barford, D. (2005) · Nature · doi:10.1038/nature03462 · Cited by 531 · see citing works

RNAi: The Nuts and Bolts of the RISC Machine

Filipowicz, W. (2005) · Cell · doi:10.1016/j.cell.2005.06.023 · Cited by 485 · see citing works

Kinetic analysis of the RNAi enzyme complex

Haley, B., & Zamore, P. D. (2004) · Nature Structural & Molecular Biology · doi:10.1038/nsmb780 · Cited by 454 · see citing works

The Mechanism Selecting the Guide Strand from Small RNA Duplexes is Different Among Argonaute Proteins

Takeda, A., Iwasaki, S., Watanabe, T., Utsumi, M., & Watanabe, Y. (2008) · Plant and Cell Physiology · doi:10.1093/pcp/pcn043 · Cited by 444 · see citing works

Drosophila microRNAs Are Sorted into Functionally Distinct Argonaute Complexes after Production by Dicer-1

Förstemann, K., Horwich, M. D., Wee, L. M., Tomari, Y., & Zamore, P. D. (2007) · Cell · doi:10.1016/j.cell.2007.05.056 · Cited by 440 · see citing works

Processing of Pre-microRNAs by the Dicer-1–Loquacious Complex in Drosophila Cells

Saito, K., Ishizuka, A., Siomi, H., & Siomi, M. C. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030235 · Cited by 437 · see citing works

In vitro reconstitution of the human RISC-loading complex

MacRae, I. J., Ma, E., Zhou, M., Robinson, C. V., & Doudna, J. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0710869105 · Cited by 435 · see citing works

A Dicer-2-Dependent 80S Complex Cleaves Targeted mRNAs during RNAi in Drosophila

Pham, J. W., Pellino, J. L., Lee, Y. S., Carthew, R. W., & Sontheimer, E. J. (2004) · Cell · doi:10.1016/s0092-8674(04)00258-2 · Cited by 425 · see citing works

A human, ATP-independent, RISC assembly machine fueled by pre-miRNAPreprint

Maniataki, E., & Mourelatos, Z. (2005) · Genes & Development · doi:10.1101/gad.1384005 · Cited by 422 · see citing works

The Stability Constants of Metal-Adenine Nucleotide Complexes

O’Sullivan, W. J., & PERRIN, D. D. (1964) · Biochemistry · doi:10.1021/bi00889a005 · Cited by 404 · see citing works

Slicer function of Drosophila Argonautes and its involvement in RISC formationPreprint

Miyoshi, K., Tsukumo, H., Nagami, T., Siomi, H., & Siomi, M. C. (2005) · Genes & Development · doi:10.1101/gad.1370605 · Cited by 402 · see citing works

Cleavage of the siRNA passenger strand during RISC assembly in human cells

Leuschner, P. J. F., Ameres, S. L., Kueng, S., & Martı̂nez, J. (2006) · EMBO Reports · doi:10.1038/sj.embor.7400637 · Cited by 399 · see citing works

Sorting of Drosophila Small Silencing RNAs

Tomari, Y., Du, T., & Zamore, P. D. (2007) · Cell · doi:10.1016/j.cell.2007.05.057 · Cited by 383 · see citing works

ATP-dependent human RISC assembly pathways

Yoda, M., Kawamata, T., Paroo, Z., Ye, X., Iwasaki, S., Liu, Q., & Tomari, Y. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1733 · Cited by 380 · see citing works

RISC Assembly Defects in the Drosophila RNAi Mutant armitage

Tomari, Y., Du, T., Haley, B., Schwarz, D. S., Bennett, R. P., Cook, H. A., Koppetsch, B. S., Theurkauf, W. E., & Zamore, P. D. (2004) · Cell · doi:10.1016/s0092-8674(04)00218-1 · Cited by 372 · see citing works

Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

Landthaler, M., Gaidatzis, D., Rothballer, A., Chen, P., Soll, S. J., Dinic, L., Ojo, T., Hafner, M., Zavolan, M., & Tuschl, T. (2008) · RNA · doi:10.1261/rna.1351608 · Cited by 355 · see citing works

Dicer-1 and R3D1-L catalyze microRNA maturation in DrosophilaPreprint

Jiang, F., Ye, X., Liu, X., Fincher, L., Mckearin, D. M., & Liu, Q. (2005) · Genes & Development · doi:10.1101/gad.1334005 · Cited by 321 · see citing works

Sorting of <i>Drosophila</i> small silencing RNAs partitions microRNA* strands into the RNA interference pathway

Ghildiyal, M., Xu, J., Seitz, H., Weng, Z., & Zamore, P. D. (2010) · RNA · doi:10.1261/rna.1972910 · Cited by 319 · see citing works

Distinct Mechanisms for MicroRNA Strand Selection by Drosophila Argonautes

Okamura, K., Liu, N., & Lai, E. C. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.09.027 · Cited by 276 · see citing works

Structural determinants of miRNAs for RISC loading and slicer-independent unwinding

Kawamata, T., Seitz, H., & Tomari, Y. (2009) · Nature Structural &amp; Molecular Biology · doi:10.1038/nsmb.1630 · Cited by 269 · see citing works

The RNA-Induced Silencing Complex Is a Mg2+-Dependent Endonuclease

Schwarz, D. S., Tomari, Y., & Zamore, P. D. (2004) · Current Biology · doi:10.1016/j.cub.2004.03.008 · Cited by 268 · see citing works

Hierarchical Rules for Argonaute Loading in Drosophila

Czech, B., Zhou, R., Erlich, Y., Brennecke, J., Binari, R. C., Villalta, C., Gordon, A., Perrimon, N., & Hannon, G. J. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.09.028 · Cited by 257 · see citing works

C3PO, an Endoribonuclease That Promotes RNAi by Facilitating RISC Activation

Liu, Y., Ye, X., Jiang, F., Liang, C., Chen, D., Peng, J., Kinch, L. N., Grishin, N. V., & Liu, Q. (2009) · Science · doi:10.1126/science.1176325 · Cited by 251 · see citing works

Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing

Azuma-Mukai, A., Oguri, H., Mitsuyama, T., Qian, Z. R., Asai, K., Siomi, H., & Siomi, M. C. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0800334105 · Cited by 249 · see citing works

Conformational changes of transfer ribonucleic acid. Equilibrium phase diagrams

Cole, P. E., Yang, S. K., & Crothers, D. M. (1972) · Biochemistry · doi:10.1021/bi00773a024 · Cited by 232 · see citing works

In vitro analyses of the production and activity of secondary small interfering RNAs in C. elegans

Aoki, K., Moriguchi, H., Yoshioka, T., Okawa, K., & Tabara, H. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601910 · Cited by 230 · see citing works

Drosophila Argonaute1 and Argonaute2 Employ Distinct Mechanisms for Translational Repression

Iwasaki, S., Kawamata, T., & Tomari, Y. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.02.010 · Cited by 193 · see citing works

Enhancement of the Seed-Target Recognition Step in RNA Silencing by a PIWI/MID Domain Protein

Parker, J. S., Parizotto, E. A., Wang, M., Roe, S. M., & Barford, D. (2009) · Molecular Cell · doi:10.1016/j.molcel.2008.12.012 · Cited by 149 · see citing works

Expanded RNA-binding activities of mammalian Argonaute 2

Tan, G. S., Garchow, B. G., Liu, X., Yeung, J., Morris, J. P., Cuellar, T. L., McManus, M. T., & Kiriakidou, M. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp812 · Cited by 127 · see citing works

QIP, a putative exonuclease, interacts with the Neurospora Argonaute protein and facilitates conversion of duplex siRNA into single strandsPreprint

Maiti, M., Lee, H.-C., & Liu, Y. (2007) · Genes & Development · doi:10.1101/gad.1497607 · Cited by 116 · see citing works

Structural features of small RNA precursors determine Argonaute loading in Caenorhabditis elegans

Steiner, F. A., Hoogstrate, S. W., Okihara, K. L., Thijssen, K. L., Ketting, R. F., Plasterk, R. H. A., & Sijen, T. (2007) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1308 · Cited by 93 · see citing works

How to slice: snapshots of Argonaute in action

Parker, J. S. (2010) · Silence · doi:10.1186/1758-907x-1-3 · Cited by 86 · see citing works

Molecular Requirements for RNA-induced Silencing Complex Assembly in the Drosophila RNA Interference Pathway

Pham, J. W., & Sontheimer, E. J. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m509202200 · Cited by 71 · see citing works

Short Interfering RNA Strand Selection Is Independent of dsRNA Processing Polarity during RNAi in Drosophila

Preall, J. B., He, Z., Gorra, J. M., et al. (2006) · Current Biology · doi:10.1016/j.cub.2006.01.061 · Cited by 52 · see citing works

Two molecular features contribute to the Argonaute specificity for the microRNA and RNAi pathways in C. elegans

Jannot, G., Boisvert, M.-E. L., Banville, I., & Simard, M. J. (2008) · RNA · doi:10.1261/rna.901908 · Cited by 43 · see citing works

Regulation of microRNA biogenesis

Ha, M., & Kim, V. N. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3838 · Cited by 5,462 · see citing works

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

O'Brien, J., Hayder, H., Zayed, Y., & Peng, C. (2018) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00402 · Cited by 5,287 · see citing works

From guide to target: molecular insights into eukaryotic RNA-interference machinery

Ipsaro, J. J., & Joshua-Tor, L. (2015) · Nature Structural &amp; Molecular Biology · doi:10.1038/nsmb.2931 · Cited by 281 · see citing works

Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential

Yuan, M., Yang, B., Rothschild, G., Mann, J. J., Sanford, L. D., Tang, X., Huang, C., Wang, C., & Zhang, W. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01519-z · Cited by 246 · see citing works

Biogenesis and mechanisms of microRNA‐mediated gene regulation

Rani, V., & Sengar, R. S. (2022) · Biotechnology and Bioengineering · doi:10.1002/bit.28029 · Cited by 172 · see citing works

The mitochondrial genome in aging and senescence

Lauri, A., Pompilio, G., & Capogrossi, M. C. (2014) · Ageing Research Reviews · doi:10.1016/j.arr.2014.07.001 · Cited by 80 · see citing works

MicroRNAs in Extracellular Vesicles of Alzheimer’s Disease

Li, W., & Zheng, Y. (2023) · Cells · doi:10.3390/cells12101378 · Cited by 43 · see citing works

ФОРМИРОВAНИЕ ГОТОВНОСТИ БУДУЩИХ ПЕДAГОГОВ К ОРГAНИЗAЦИИ РAБОТЫ ПО РAЗВИТИЮ ВAЛЕОЛОГИЧЕСКОЙ КУЛЬТУРЫ ШКОЛЬНИКОВ

БАЗАРБАЕВА, Ә. А., Майгельдиева, Ш. М., & ЖҮНДІБАЕВА, Т. Н. (2023) · Pedagogy and Psychology · doi:10.51889/2077-6861.2023.1.30.016

Коммуникaтивно- прaгмaтический aнaлиз дипломaтических бумaг (нa основе вербaльных нот)

Кaмирдиновa, Н., & Кaлиевa, Ш. С. (2018) · DOAJ (DOAJ: Directory of Open Access Journals)

DETERMINING QUALITY REQUIREMENTS AT THE UNIVERSITIES TO IMPROVE THE QUALITY OF EDUCATION

Mustafa, N. H., Kelesbayev, D., & Alibekova, Z. D. (2018) · The Journal of Economic Research & Business Administration · doi:10.26577/be-2018-2-2141

Susquehanna Chorale Spring Concert "Roots and Wings"

Hawkins, D. (2017)

A GEOMETRIC MEAN IN THE FURUTA INEQUALITY

Fujii, M., & Nakamoto, R. (2002) · Scientiae mathematicae Japonicae · Cited by 15 · see citing works