The Influence of CYP1A2 Genotype in the Blood Pressure Response to Caffeine Ingestion Is Affected by Physical Activity Status and Caffeine Consumption Level
Open accessAbstract
This study aimed to investigate whether the influence of CYP1A2 genotype in the blood pressure (BP) response to caffeine ingestion was affected by physical activity status and habitual caffeine consumption. Thirty-seven participants (19-50 years old) took place in the study and were categorized according to i) genotype: CYP1A2 (AA) "fast metabolizer", and CYP1A2 (AC) "slow metabolizer"; ii) physical activity level: sedentary (S) and physically active (A); and iii) caffeine consumption level: non-habitual caffeine consumer (NC) and habitual heavy caffeine consumer (C). All groups had BP assessed before (basal) and 1 hourh after (post) caffeine ingestion (6 mg·kg-1). It was observed that AC genotype individuals had increased basal-DBP and post-caffeine SBP when compared to AA individuals. Additionally, acute caffeine ingestion increased SBP only in the AC group. It was also found that physical activity only modulated the BP responses to acute caffeine ingestion in AC individuals. Furthermore, the results indicated that the habitual heavy caffeine consumers AC individuals had increased basal-DBP when compared to the AA ones. Our results suggest that the influence of CYP1A2 genotype in the basal and post-caffeine BP response to caffeine ingestion is modified by physical activity status and caffeine consumption level.
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The effect of CYP1A2 genotype on blood pressure responses is further modulated by both physical activity levels and habitual caffeine consumption.
“Studies have already demonstrated that *CYP1A2* genotype can influence blood pressure responses following caffeine intake, and this effect is further modulated by both physical activity levels and habitual caffeine consumption [97].”
From Pre-Exercise Caffeine as a Modulator of Exercise-Induced Acute Cardiometabolic Responses: A Narrative Review (2026) · cites this paper as [97]
CYP1A2 genotype can influence blood pressure responses following caffeine intake.
“Studies have already demonstrated that *CYP1A2* genotype can influence blood pressure responses following caffeine intake, and this effect is further modulated by both physical activity levels and habitual caffeine consumption [97].”
From Pre-Exercise Caffeine as a Modulator of Exercise-Induced Acute Cardiometabolic Responses: A Narrative Review (2026) · cites this paper as [97]
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Cites
Pickering, T. G., Hall, J. E., Appel, L. J., Falkner, B. E., Graves, J., Hill, M. N., Jones, D. W., Kurtz, T., Sheps, S. G., & Roccella, E. J. (2005) · Circulation · doi:10.1161/01.cir.0000154900.76284.f6 · Cited by 3,985 · see citing works
Endothelial Nitric Oxide Synthase in Vascular Disease: From Marvel to Menace
Förstermann, U., & Münzel, T. (2006) · Circulation · doi:10.1161/circulationaha.105.602532 · Cited by 1,957 · see citing works
Exercise Training for Blood Pressure: A Systematic Review and Meta‐analysis
Cornelissen, V. A., & Smart, N. A. (2013) · Journal of the American Heart Association · doi:10.1161/jaha.112.004473 · Cited by 1,683 · see citing works
Heckman, M. A., Weil, J., & de Mejı́a, E. G. (2010) · Journal of Food Science · doi:10.1111/j.1750-3841.2010.01561.x · Cited by 1,072 · see citing works
Caffeinated energy drinks a growing problem
Reissig, C. J., Strain, E. C., & Griffiths, R. R. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2008.08.001 · Cited by 1,026 · see citing works
Nitric oxide and oxidative stress in vascular disease
Förstermann, U. (2010) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-010-0808-2 · Cited by 780 · see citing works
Sachse, C., Brockmöller, J., Bauer, S., & Roots, I. (1999) · British Journal of Clinical Pharmacology · doi:10.1046/j.1365-2125.1999.00898.x · Cited by 751 · see citing works
Direct Evidence of Endothelial Oxidative Stress With Aging in Humans
Donato, A. J., Eskurza, I., Silver, A., Levy, A., Pierce, G. L., Gates, P. E., & Seals, D. R. (2007) · Circulation Research · doi:10.1161/01.res.0000269183.13937.e8 · Cited by 558 · see citing works
Coffee, CYP1A2 genotype, and risk of myocardial infarction
Cornelis, M. C., El-Sohemy, A., Kabagambe, E. K., & Campos, H. (2006) · JAMA · doi:10.1001/jama.295.10.1135 · Cited by 490 · see citing works
Coffee, caffeine and blood pressure: a critical review
Nurminen, M.-L., Niittynen, L., Korpela, R., & Vapaatalo, H. (1999) · European Journal of Clinical Nutrition · doi:10.1038/sj.ejcn.1600899 · Cited by 351 · see citing works
Stice, E. M., Yokum, S., Bohon, C., Marti, N., & Smolen, A. (2010) · NeuroImage · doi:10.1016/j.neuroimage.2010.01.081 · Cited by 333 · see citing works
The impact of coffee on health
Cano-Marquina, A., Tarín, J. J., & Cano, A. (2013) · Maturitas · doi:10.1016/j.maturitas.2013.02.002 · Cited by 332 · see citing works
Invited review: activity-induced angiogenesis
Egginton, S. (2008) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-008-0563-9 · Cited by 259 · see citing works
CYP1A2 genotype modifies the association between coffee intake and the risk of hypertension
Palatini, P., Ceolotto, G., Ragazzo, F., Dorigatti, F., Saladini, F., Papparella, I., Mos, L., Zanata, G., & Santonastaso, M. (2009) · Journal of Hypertension · doi:10.1097/hjh.0b013e32832ba850 · Cited by 230 · see citing works
Effects of Acute Administration of Caffeine on Vascular Function
Umemura, T., Ueda, K., Nishioka, K., Hidaka, T., Takemoto, H., Nakamura, S., Jitsuiki, D., Soga, J., Goto, C., Chayama, K., et al. (2006) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2006.06.058 · Cited by 189 · see citing works
Monahan, K. D., Dinenno, F. A., Tanaka, H., Clevenger, C. M., DeSouza, C. A., & Seals, D. R. (2000) · The Journal of Physiology · doi:10.1111/j.1469-7793.2000.00263.x · Cited by 185 · see citing works
The Acute Physiological and Mood Effects of Tea and Coffee
Quinlan, P. T., Lane, J., Moore, K. L., Aspen, J. M., Rycroft, J. A., & O'Brien, D. (2000) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(00)00192-1 · Cited by 182 · see citing works
Stofan, J. R., DiPietro, L., Davis, D., Kohl, H. W., & Blair, S. N. (1998) · American Journal of Public Health · doi:10.2105/ajph.88.12.1807 · Cited by 180 · see citing works
Beck, T. W., Housh, T. J., Schmidt, R. J., Johnson, G. O., Housh, D. J., Coburn, J. W., & Malek, M. H. (2006) · The Journal of Strength and Conditioning Research · doi:10.1519/18285.1 · Cited by 176 · see citing works
Caffeine Intake, Tolerance, and Withdrawal in Women: A Population-Based Twin Study
Kendler, K. S., & Prescott, C. A. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.2.223 · Cited by 125 · see citing works
Coffee Consumption and Coronary Heart Disease in Women
Willett, W. C. (1996) · JAMA · doi:10.1001/jama.1996.03530300042038 · Cited by 116 · see citing works
Ray, C. J., & Marshall, J. M. (2005) · The Journal of Physiology · doi:10.1113/jphysiol.2005.099390 · Cited by 113 · see citing works
Effects of caffeine with repeated dosing
Denaro, C. P., Brown, C. R., Jacob, P., & Benowitz, N. L. (1991) · European Journal of Clinical Pharmacology · doi:10.1007/bf00315208 · Cited by 106 · see citing works
Blood Pressure Response to Caffeine Shows Incomplete Tolerance After Short-Term Regular Consumption
Lovallo, W. R., Wilson, M. F., Vincent, A. S., Sung, B. H., McKey, B. S., & Whitsett, T. L. (2004) · Hypertension · doi:10.1161/01.hyp.0000120965.63962.93 · Cited by 105 · see citing works
Caffeine and Cardiac Arrhythmias: A Review of the Evidence
Pelchovitz, D. J., & Goldberger, J. J. (2011) · The American Journal of Medicine · doi:10.1016/j.amjmed.2010.10.017 · Cited by 94 · see citing works
Ammon, H., Bieck, P., Mandalaz, D., & Verspohl, E. (1983) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1983.tb01553.x · Cited by 86 · see citing works
GREEN, D. J., Eijsvogels, T. M. H., Bouts, Y. M., Maiorana, A., Naylor, L. H., Scholten, R. R., Spaanderman, M. E. A., Pugh, C. J. A., Sprung, V. S., Schreuder, T. H. A., et al. (2014) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00354.2014 · Cited by 86 · see citing works
Farin, F. M., Pohlman, T. H., & Omiecinski, C. J. (1994) · Toxicology and Applied Pharmacology · doi:10.1006/taap.1994.1001 · Cited by 85 · see citing works
Exercise training restores the endothelial progenitor cells number and function in hypertension
Fernandes, T. M., Nakamuta, J. S., Magalhães, F. D. C., Roque, F. R., Lavini‐Ramos, C., Schettert, I. T., Coelho, V. P. C. V., Krieger, J. E., & de Oliveira, E. M. (2012) · Journal of Hypertension · doi:10.1097/hjh.0b013e3283588d46 · Cited by 75 · see citing works
Energy drink ingredients. Contribution of caffeine and taurine to performance outcomes
Peacock, A., Martin, F. H., & Carr, A. R. (2013) · Appetite · doi:10.1016/j.appet.2012.12.021 · Cited by 72 · see citing works
Clarke, N. D., Kornilios, E., & Richardson, D. L. (2015) · Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000000945 · Cited by 71 · see citing works
Guessous, I., Dobrinas, M., Kutalik, Z., Pruijm, M., Ehret, G., Maillard, M., Bergmann, S., Beckmann, J. S., Cusi, D., Rizzi, F., et al. (2012) · Human Molecular Genetics · doi:10.1093/hmg/dds137 · Cited by 70 · see citing works
Genetic determinants of blood pressure responses to caffeine drinking
Renda, G., Zimarino, M., Antonucci, I., Tatasciore, A., Ruggieri, B., Bucciarelli, T., Prontera, T., Stuppia, L., & Caterina, R. D. (2011) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.111.018267 · Cited by 69 · see citing works
Moker, E., Bateman, L. A., Kraus, W. E., & Pescatello, L. S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0105755 · Cited by 65 · see citing works
Perera, V., Gross, A. S., & McLachlan, A. J. (2012) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.2012.139 · Cited by 64 · see citing works
Thum, T., Haverich, A., & Borlak, J. T. (2000) · The FASEB Journal · doi:10.1096/fasebj.14.5.740 · Cited by 63 · see citing works
CYP1A2 protects against reactive oxygen production in mouse liver microsomes
Shertzer, H. G., Clay, C. D., Genter, M. B., Schneider, S. N., Nebert, D. W., & Dalton, T. P. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2003.11.013 · Cited by 58 · see citing works
Effects of caffeine on baroreflex activity in humans
Mosqueda-Garcia, R., Tseng, C.-J., Biaggioni, I., Robertson, R. M., & Robertson, D. (1990) · Clinical Pharmacology and Therapeutics · doi:10.1038/clpt.1990.193 · Cited by 54 · see citing works
Genetics of coffee consumption and its stability
Laitala, V. S., Kaprio, J. A., & Silventoinen, K. (2008) · Addiction · doi:10.1111/j.1360-0443.2008.02375.x · Cited by 44 · see citing works
The Effects of Red Bull Energy Drink Compared With Caffeine on Cycling Time-Trial Performance
Quinlivan, A., Irwin, C. G., Grant, G. D., Anoopkumar-Dukie, S., Skinner, T. L., LEVERITT, M. D., & Desbrow, B. (2015) · International Journal of Sports Physiology and Performance · doi:10.1123/ijspp.2014-0481 · Cited by 43 · see citing works
Hemodynamic Mechanisms Underlying the Incomplete Tolerance to Caffeine's Pressor Effects
Farag, N. H., Vincent, A. S., McKey, B. S., Whitsett, T. L., & Lovallo, W. R. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2005.01.093 · Cited by 41 · see citing works
Changes in Gene Expression in Responders and Nonresponders to a Low-Intensity Walking Intervention
Osler, M. E., Fritz, T., Caidahl, K., Krook, A., Zierath, J. R., & Wallberg‐Henriksson, H. (2015) · Diabetes Care · doi:10.2337/dc14-2606 · Cited by 38 · see citing works
Doerner, J., Kuetting, D. L. R., Luetkens, J. A., Naehle, C. P., Dabir, D., Homsi, R., Nadal, J., Schild, H. H., & Thomas, D. K. (2014) · International journal of cardiac imaging · doi:10.1007/s10554-014-0577-7 · Cited by 36 · see citing works
Caffeine-induced endothelial cell death and the inhibition of angiogenesis
Li, H., Jin, S., Son, H.-J., Seo, J. H., & Jeong, G. (2013) · Anatomy & Cell Biology · doi:10.5115/acb.2013.46.1.57 · Cited by 33 · see citing works
McMullen, M. K., Whitehouse, J. M., Shine, G., & Towell, A. (2011) · Food & Function · doi:10.1039/c0fo00166j · Cited by 30 · see citing works
Caffeine Tolerance is Incomplete: Persistent Blood Pressure Responses in the Ambulatory Setting
FARAG, N., VINCENT, A., SUNG, B., WHITSETT, T., WILSON, M., & LOVALLO, W. (2005) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2005.03.738 · Cited by 29 · see citing works
Acute and chronic caffeine administration increases physical activity in sedentary adults
Schrader, P., Panek-Shirley, L. M., & Temple, J. L. (2013) · Nutrition Research · doi:10.1016/j.nutres.2013.04.003 · Cited by 18 · see citing works
Souza, D., Casonatto, J., Poton, R., Willardson, J., & Polito, M. (2014) · Research in Sports Medicine · doi:10.1080/15438627.2014.915832 · Cited by 16 · see citing works
Obesity and Hypertension among School-going Adolescents in Peru
Nam, E. W., Sharma, B., Kim, H. Y., Paja, D. J. V., Yoon, Y. M., Lee, S. H., Kim, E. H., Oh, C. H., Kim, Y. S., Song, C., et al. (2015) · Journal of Lifestyle Medicine · doi:10.15280/jlm.2015.5.2.60 · Cited by 16 · see citing works
Soares, R. N., Schneider, A., Valle, S. C., & Schenkel, P. C. (2016) · Journal of Caffeine Research · doi:10.1089/jcr.2016.0017 · Cited by 7 · see citing works
Self-citationThe Effect of Caffeine on Peripheral Vascular Resistance in Isolated Perfused Guinea Pig Hind Limbs
Brodmann, M., Lischnig, U., Lueger, A., Pilger, E., & Stark, G. (2003) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-200310000-00008 · Cited by 6 · see citing works
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1 of the 52 references couldn’t be matched to a known paper.
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International Society of Sports Nutrition Position Stand: Caffeine and Exercise Performance
Guest, N. S., VanDusseldorp, T. A., Nelson, M. T., Grgic, J., Schoenfeld, B. J., Jenkins, N. D. M., Arent, S. M., Antonio, J., Stout, J. R., Trexler, E. T., et al. (2021) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-020-00383-4 · Cited by 665 · see citing works
Sport Nutrigenomics: Personalized Nutrition for Athletic Performance
Guest, N. S., Horne, J. R., Vanderhout, S. M., & El‐Sohemy, A. (2019) · Frontiers in Nutrition · doi:10.3389/fnut.2019.00008 · Cited by 184 · see citing works
Zhou, A., & Hyppönen, E. (2018) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqy297 · Cited by 120 · see citing works
Risk or benefit? Side effects of caffeine supplementation in sport: a systematic review
de Souza, J. G., Coso, J. D., Fonseca, F. D. S., da Silva, B. V. C., de Souza, D. B., Gianoni, R. L. D. S., Filip-Stachnik, A., Serrão, J. C., & Claudino, J. G. (2022) · European Journal of Nutrition · doi:10.1007/s00394-022-02874-3 · Cited by 117 · see citing works
Coffee and Arterial Hypertension
Surma, S., & Oparil, S. (2021) · Current Hypertension Reports · doi:10.1007/s11906-021-01156-3 · Cited by 92 · see citing works
Impact of Genetic Variability on Physiological Responses to Caffeine in Humans: A Systematic Review
Fulton, J. L., Dinas, P. C., Carrillo, A. E., Edsall, J. R., Ryan, E. J., & Ryan, E. J. (2018) · Nutrients · doi:10.3390/nu10101373 · Cited by 70 · see citing works
Soares, R. N., George, M. A., Proctor, D. N., & Murias, J. M. (2018) · European Journal of Applied Physiology · doi:10.1007/s00421-018-3955-3 · Cited by 51 · see citing works
Self-citationNicolopoulos, K., Mulugeta, A., Zhou, A., & Hyppönen, E. (2020) · Clinical Nutrition · doi:10.1016/j.clnu.2020.03.009 · Cited by 40 · see citing works
Genetic Polymorphisms in ADORA2A and CYP1A2 Influence Caffeine’s Effect on Postprandial Glycaemia
Banks, N. F., Tomko, P. M., Colquhoun, R. J., Muddle, T. W. D., Emerson, S. R., & Jenkins, N. D. M. (2019) · Scientific Reports · doi:10.1038/s41598-019-46931-0 · Cited by 39 · see citing works
Xing, D., Yoo, C., Gonzalez, D. E., Jenkins, V. M., Nottingham, K., Dickerson, B. L., Leonard, M., Ko, J., Faries, M. B., Kephart, W. C., et al. (2021) · Nutrients · doi:10.3390/nu13124478 · Cited by 25 · see citing works
Yoshihara, T., Zaitsu, M., Shiraishi, F., Arima, H., Takahashi‐Yanaga, F., Arioka, M., Kajioka, S., & Sasaguri, T. (2019) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2019.01.006 · Cited by 21 · see citing works
Hou, C.-C., Tantoh, D. M., Lin, C.-C., Chen, P.-H., Yang, H., & Liaw, Y. (2021) · Nutrition & Metabolism · doi:10.1186/s12986-021-00605-9 · Cited by 19 · see citing works
Effect of Caffeine on Endurance Performance in Athletes May Depend on HTR2A and CYP1A2 Genotypes
Guest, N. S., Corey, P., Tyrrell, P. N., & El‐Sohemy, A. (2020) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000003665 · Cited by 19 · see citing works
Effect of Caffeine in Hypertension
Islam, R., Ahmed, M., Ullah, W., Tahir, Y. B., Gul, S., Hussain, N., Islam, H., & Anjum, M. U. (2023) · Current Problems in Cardiology · doi:10.1016/j.cpcardiol.2023.101892 · Cited by 16 · see citing works
Barati, S., Fabrizio, C., Strafella, C., Cascella, R., Caputo, V., Megalizzi, D., Peconi, C., Mela, J., Colantoni, L., Caltagirone, C., et al. (2022) · Genes · doi:10.3390/genes13081498 · Cited by 14 · see citing works
Caffeine ingestion alters central hemodynamics following aerobic exercise in middle-aged men
Harber, M. P., McCurry, A., Carlini, N., Kistler, B., & Fleenor, B. S. (2021) · European Journal of Applied Physiology · doi:10.1007/s00421-020-04521-3 · Cited by 11 · see citing works
Virgili, J., Motitis, P., Julal, G., Mavrommatis, Y., & Pilić, L. (2023) · Nutrition Bulletin · doi:10.1111/nbu.12606 · Cited by 9 · see citing works
Zheng, J., Chen, H., Yang, Q., Zhou, Z., Yang, C., Huang, J., Tu, Q., Wu, H., Qiu, P., Huang, W., et al. (2024) · Heart Rhythm · doi:10.1016/j.hrthm.2024.11.047 · Cited by 8 · see citing works
Direct-to-Consumer Genetic Testing in Korea: Current Status and Significance in Clinical Nutrition
Lee, G. Y., & Han, S. N. (2021) · Clinical Nutrition Research · doi:10.7762/cnr.2021.10.4.279 · Cited by 8 · see citing works
The Effect of Coffee Consumption on Blood Glucose Levels
BaSalamah, M., AlMghamsi, R., Altowairqi, A. S., Fouda, K., Mahrous, A., Mujahid, M., Sindi, H., & Aldairi, A. F. (2022) · Journal Of Biochemical Technology · doi:10.51847/volnukyp3c · Cited by 6 · see citing works
Coffee and health: what we still don't know
El‐Sohemy, A. (2018) · American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqy368 · Cited by 4 · see citing works
Gross, K. N., Allen, L. E., Hagele, A. M., Krieger, J. M., Sutton, P. J., Duncan, E., Mumford, P. W., Jäger, R., Purpura, M., & Kerksick, C. M. (2024) · Journal of Dietary Supplements · doi:10.1080/19390211.2024.2351222 · Cited by 3 · see citing works
Amjad, G., Saif, R., & Hussain, M. G. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.10.07.561327 · Cited by 3 · see citing works
Geng, H., Zhou, Z., Meng, L., Zhuang, M., & Zhao, Y. (2026) · Metabolites · doi:10.3390/metabo16070478 · Cited by 2 · see citing works
“Studies have already demonstrated that *CYP1A2* genotype can influence blood pressure responses following caffeine intake, and this effect is further modulated by both physical activity levels and habitual caffeine consumption [97].”
Caffeine and Cardiovascular Outcomes: Current Evidence and Clinical Perspectives
Neshat, N., Frishman, W. H., & Aronow, W. S. (2026) · Cardiology in Review · doi:10.1097/crd.0000000000001252 · Cited by 2 · see citing works
Popa, L. C., Abu-Awwad, A., Farcaş, S. S., Abu-Awwad, S.-A., & Andreescu, N. I. (2025) · Metabolites · doi:10.3390/metabo15070450 · Cited by 2 · see citing works
Kusic, D., Zajic, S. C., Gharani, N., Gordon, E. S., Schmidlen, T., Zhang, P., Gerry, N. P., & Scheinfeldt, L. (2023) · Genetics & Molecular Medicine · doi:10.33425/2689-1077.1020 · Cited by 2 · see citing works
Genetic Modifiers of Caffeine and Endurance Performance in Athletes
Guest, N. S. (2019) · TSpace (University of Toronto) · Cited by 2 · see citing works
Zart, S., Dindorf, C., & Fröhlich, M. (2024) · Scientific Journal of Sport and Performance · doi:10.55860/ennp5024 · Cited by 1 · see citing works
Zart, S., Dindorf, C., & Fröhlich, M. (2023) · Preprints.org · doi:10.20944/preprints202304.0631.v1 · Cited by 1 · see citing works
The future of genetically based nutritional and pharmacological ergogenic aids in sport
Guest, N. S., García‐Bailo, B., Eny, K. M., Joffre, S., & El‐Sohemy, A. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816193-7.00020-8
The Neural Correlates of Expectations Effects
Wicht, C. A. (2022) · doi:10.51363/unifr.sth.2022.003
Sports Nutrigenomics – Caffeine: A Review
., M. (2024) · Journal of Exercise Science and Physiotherapy · doi:10.18376/jesp/2024/v20/i2/47752
Djordjevic, N. (2025) · Royal Society of Chemistry eBooks · doi:10.1039/9781839166853-00341
Nutrigenomics and sports performance
Shivsharan, R. R., Ayyar, P. V., Akkalkote, R. S., Bhagwat, P. K., Patil, V. B., & Pillai, S. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-26761-1.00006-5
- Authors
- Soares, R. N., Schneider, A., Valle, S. C., & Schenkel, P. C.
- Affiliations
- Universidade Federal de Pelotas (BR)
- Universidade Federal do Rio Grande do Sul (BR)
- Venue
- Vascular Pharmacology
- Publisher
- Elsevier BV
- Published
- 2018-07
- Volume
- 106
- Pages
- 67-73
- ISSN
- 1537-1891 (ISSN-L)
- OpenAlex
- W2790483110
- Cited by
- 35
- References
- 52
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 4 · 2023: 5 · 2022: 4 · 2021: 5 · 2020: 3 · 2019: 5 · 2018: 4
- FWCI
- 2.74
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Vascular Pharmacology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- CAPES (99999.001395/2015-07)
- Topics
- Health Sciences › Medicine › Pharmacology › Coffee research and impacts
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacogenetics and Drug Metabolism
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Keywords
- caffeine ingestion, blood pressure response, physical activity, habitual caffeine consumption, sedentary behavior, systolic blood pressure, diastolic blood pressure, gene-environment interaction
- MeSH terms
- Pharmacogenomic Variants, Administration, Oral, Adult, Central Nervous System Stimulants, Blood Pressure, Caffeine, Capsules, Diet, Female, Humans, Male, Middle Aged, Pharmacogenetics, Phenotype, Surveys and Questionnaires, Exercise, Cytochrome P-450 CYP1A2, Young Adult, Sedentary Behavior
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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