Cited by 516Heart Failure Treatment and ManagementCardiovascular Function and Risk FactorsDiabetes, Cardiovascular Risks, and Lipoproteins

Diabetes mellitus, a predictor of morbidity and mortality in the Studies of Left Ventricular Dysfunction (SOLVD) Trials and Registry

Shindler, Daniel M., Kostis, John B., Yusuf, Salim, Quinones, Miguel A., Pitt, Bertram, Stewart, Dawn, Pinkett, Tamara, Ghali, Jalal K. +2 more·1996·The American Journal of Cardiology

Abstract

Diabetes is an independent predictor of morbidity and mortality in patients with symptomatic heart failure, patients with asymptomatic left ventricular dysfunction (defined as an ejection fraction of 35% or less), and in a broader registry population with less stringent entry criteria. Although the SOLVD Trials made a major clinical contribution by proving the value of enalapril, diabetes remains a significant predictor of outcome even after adjusting for treatment with enalapril.

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Crossref · 10.1016/s0002-9149(97)89163-1

Cites

22 of 22 references verified0 citation errors · 0 not checkable

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Authors
Shindler, D. M., Kostis, J. B., Yusuf, S., Quinones, M. A., Pitt, B., Stewart, D., Pinkett, T., Ghali, J. K., Wilson, A. C., & The SOLVD Investigators
Affiliations
Rutgers, The State University of New Jersey (US)
Venue
The American Journal of Cardiology
Publisher
Elsevier BV
Published
1996-05
Volume
77
Issue
11
Pages
1017-1020
ISSN
0002-9149 (ISSN-L)
OpenAlex
W2161659925
Cited by
516
References
22
Citations by year
2026: 6 · 2025: 6 · 2024: 9 · 2023: 13 · 2022: 11 · 2021: 11 · 2020: 20 · 2019: 12 · 2018: 16 · 2017: 16 · 2016: 20 · 2015: 22 · 2014: 22 · 2013: 14 · 2012: 19
FWCI
4.05
Type
journal article
Language
en
Open access
closed
Locations
  • The American Journal of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Failure Treatment and Management
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
diabetes mellitus, left ventricular dysfunction, heart failure, mortality, morbidity, SOLVD trial, enalapril, ejection fraction, prognosis
MeSH terms
Angiotensin-Converting Enzyme Inhibitors, Diabetes Mellitus, Enalapril, Female, Heart Failure, Humans, Male, Prognosis, Registries, Regression Analysis, Risk Factors, Multicenter Studies as Topic, Odds Ratio, Randomized Controlled Trials as Topic, Ventricular Dysfunction, Left, Diabetes Complications

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