Impact of major depression on chronic medical illness
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Depression and anxiety are more prevalent in people with long-term physical conditions and more than seven times more common in those with two or more chronic physical conditions.
“Depression and anxiety are more prevalent in people with long-term physical condition(s) and more than seven times more common in those with two or more chronic physical conditions [6].”
From Can support workers from AgeUK deliver an intervention to support older people with anxiety and depression? A qualitative evaluation (2019) · cites this paper as [6]
Major depressive disorder is associated with higher risk of early death from a broad set of physical disorders and from suicide.
“MDD is also associated with elevated risk of onset, persistence, and severity of a wide range of chronic physical disorders as well as with increased early mortality due to an even wider range of physical disorders and to suicide.”
From The Costs of Depression (2012) · cites this paper as [106]
Major depressive disorder is associated with significantly elevated risk of early death, partly due to high suicide risk and partly due to elevated risk of many physical disorders; it is also associated with elevated mortality risk among people with certain disorders as part of a larger pattern of associations with disorder severity.
“MDD is associated with significantly elevated risk of early death.104, 106, 119 This is true partly because people with MDD have high suicide risk,120–122 but also because depression is associated with elevated risk of the many types of disorders noted above. MDD is also associated with elevated mortality risk among people with certain kinds of disorders as part of a larger pattern of associations”
From The Costs of Depression (2012) · cites this paper as [106]
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“This compares with rates of 2% o 4% in the general population and 5% to 10% among primary are patients.(4,5) Furthermore, studies of long-term outcomes ave noted high rates of depression as far out as 10 to 20 years ostinjury.”
ResultPrevalence and impact of depression in cystic fibrosis
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STDD: Short-Term Depression Detection with Passive Sensing
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“People with depression experience not only psychological difficulties but also physical symptoms and show higher suicide rates (200% compared to general population), resulting in higher medical costs [2,3].”
BackgroundFatigue and psychiatric illness in a large community sample of persons with multiple sclerosis
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“Alternatively, depression amplifies the physical complaints of persons with a variety of chronic medical conditions [60] and may also amplify selfreported fatigue.”
BackgroundBehavior vs. introspection: refining prediction of clinical depression via smartphone sensing data
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Potentially Modifiable Factors Associated With Disability Among People With Diabetes
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“Although depression has been associated with fewer missed appointments in psychiatric clinics [13], in medical settings, depression is often associated with increased utilization [14], and depression in patients with HIV [15] and antidepressant use in patients with diabetes [10] are associated with increased missed ap…”
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Mental Disorder Comorbidity in Te Rau Hinengaro: The New Zealand Mental Health Survey
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Prevalence of symptoms of anxiety and depression in German patients with cystic fibrosis
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“…generally many are at an increased risk for lower emotional well-being (Heinze, Kruger, Reischl, Cupal, & Zimmerman, 2015), depression and anxiety (Clarke & Currie, 2009; Patten, 2001), and this may further hinder adjustment to the condition and increase symptom burden (Katon & Ciechanowski, 2002).”
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- Authors
- Katon, W., & Ciechanowski, P.
- Affiliations
- University of Washington (US)
- Corresponding author
- Katon, Wayne
- ORCID
- Ciechanowski, Paul
- Venue
- Journal of Psychosomatic Research
- Publisher
- Elsevier BV
- Published
- 2002-10
- Volume
- 53
- Issue
- 4
- Pages
- 859-863
- ISSN
- 0022-3999 (ISSN-L)
- OpenAlex
- W2046779437
- Cited by
- 485
- References
- 61
- Citations by year
- 2026: 8 · 2025: 10 · 2024: 20 · 2023: 16 · 2022: 11 · 2021: 24 · 2020: 20 · 2019: 21 · 2018: 14 · 2017: 29 · 2016: 27 · 2015: 27 · 2014: 34 · 2013: 30 · 2012: 27
- FWCI
- 1.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychosomatic Research (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institute of Mental Health (MH0-11643, MH4-1739)
- Topics
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Keywords
- major depressive disorder, chronic disease, cognitive behavioral therapy, depression relapse prevention, depression recurrence, antidepressants, follow-up duration
- MeSH terms
- Aging, Chronic Disease, Depressive Disorder, Diabetes Mellitus, Heart Diseases, Humans, Self Care, United States, Comorbidity
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